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A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1007/s00438-014-0885-6openalex-snapshot
Meta-analysis of genome-wide association study of homeostasis model assessment β cell function and insulin resistance in an East Asian population and the European results
inferred← citeshttps://doi.org/10.1007/s00438-019-01552-0openalex-snapshot
Heterogeneous impact of type 2 diabetes mellitus-related genetic variants on gestational glycemic traits: review and future research needs
inferred← citeshttps://doi.org/10.1007/s00439-014-1525-2openalex-snapshot
Differential positive selection of malaria resistance genes in three indigenous populations of Peninsular Malaysia
inferred← citeshttps://doi.org/10.1007/s00592-017-0987-9openalex-snapshot
Exploring single nucleotide polymorphisms previously related to obesity and metabolic traits in pediatric-onset type 2 diabetes
inferred← citeshttps://doi.org/10.1007/s00592-023-02230-9openalex-snapshot
Association between a polygenic lipodystrophy genetic risk score and diabetes risk in the high prevalence Maltese population
inferred← citeshttps://doi.org/10.1007/s10157-024-02566-8openalex-snapshot
Causality between diabetes and membranous nephropathy: Mendelian randomization
inferred← citeshttps://doi.org/10.1007/s10528-012-9552-yopenalex-snapshot
Influence of Adiponectin and Resistin Gene Polymorphisms on Quantitative Traits Related to Metabolic Syndrome Among Malay, Chinese, and Indian Men in Malaysia
inferred← citeshttps://doi.org/10.1007/s10654-017-0290-7openalex-snapshot
Epidemiology in Germany—general development and personal experience
inferred← citeshttps://doi.org/10.1007/s11239-019-01855-4openalex-snapshot
The pleiotropic effect of rs7903146 on type 2 diabetes and ischemic stroke: a family-based study in a Chinese population
inferred← citeshttps://doi.org/10.1007/s11250-022-03057-2openalex-snapshot
Association between host genetics of sheep and the rumen microbial composition
inferred← citeshttps://doi.org/10.1007/s11695-019-03964-8openalex-snapshot
Metabolically Healthy Obesity and Bariatric Surgery
inferred← citeshttps://doi.org/10.1007/s11886-014-0502-7openalex-snapshot
Functional Genomics of the 9p21.3 Locus for Atherosclerosis: Clarity or Confusion?
inferred← citeshttps://doi.org/10.1007/s11886-016-0755-4openalex-snapshot
Genetics of Insulin Resistance and the Metabolic Syndrome
inferred← citeshttps://doi.org/10.1007/s11892-012-0360-xopenalex-snapshot
Maternal/Fetal Determinants of Insulin Resistance in Women During Pregnancy and in Offspring Over Life
inferred← citeshttps://doi.org/10.1007/s11892-012-0361-9openalex-snapshot
Epigenetics of Insulin Resistance: An Emerging Field in Translational Medicine
inferred← citeshttps://doi.org/10.1007/s11892-014-0477-1openalex-snapshot
Nutrigenetics: Bridging Two Worlds to Understand Type 2 Diabetes
inferred← citeshttps://doi.org/10.1007/s11892-014-0551-8openalex-snapshot
Insights into the Genetic Susceptibility to Type 2 Diabetes from Genome-Wide Association Studies of Glycaemic Traits
inferred← citeshttps://doi.org/10.1007/s11892-015-0648-8openalex-snapshot
Insights into the Genetic Susceptibility to Type 2 Diabetes from Genome-Wide Association Studies of Obesity-Related Traits
inferred← citeshttps://doi.org/10.1007/s11892-015-0651-0openalex-snapshot
Genetics of Type 2 Diabetes in African Americans
inferred← citeshttps://doi.org/10.1007/s11892-016-0758-yopenalex-snapshot
Putting the Genome in Context: Gene-Environment Interactions in Type 2 Diabetes
inferred← citeshttps://doi.org/10.1007/s11892-017-0908-xopenalex-snapshot
Mechanisms of Type 2 Diabetes Risk Loci
inferred← citeshttps://doi.org/10.1007/s11892-018-1009-1openalex-snapshot
Prioritising Risk Factors for Type 2 Diabetes: Causal Inference through Genetic Approaches
inferred← citeshttps://doi.org/10.1007/s11892-019-1230-6openalex-snapshot
Pancreatic Islet Transcriptional Enhancers and Diabetes
inferred← citeshttps://doi.org/10.1007/s11892-020-01355-3openalex-snapshot
Genetic Studies of Gestational Diabetes and Glucose Metabolism in Pregnancy
inferred← citeshttps://doi.org/10.1007/s12020-024-03766-8openalex-snapshot
Shared genetic architecture between periodontal disease and type 2 diabetes: a large scale genome-wide cross-trait analysis
inferred← citeshttps://doi.org/10.1007/s12170-013-0368-zopenalex-snapshot
Current Insights into the Joint Genetic Basis of Type 2 Diabetes and Coronary Heart Disease
inferred← citeshttps://doi.org/10.1007/s12170-014-0418-1openalex-snapshot
Endogenous Production of Long-Chain Polyunsaturated Fatty Acids and Metabolic Disease Risk
inferred← citeshttps://doi.org/10.1007/s12529-017-9639-2openalex-snapshot
Fasting Glucose and the Risk of Depressive Symptoms: Instrumental-Variable Regression in the Cardiovascular Risk in Young Finns Study
inferred← citeshttps://doi.org/10.1007/s12672-025-02177-zopenalex-snapshot
Assessing the effect of modifiable risk factors on hepatocellular carcinoma: evidence from a bidirectional Mendelian randomization analysis
inferred← citeshttps://doi.org/10.1007/s12672-025-02237-4openalex-snapshot
Mendelian randomization study on the causal relationships among fasting blood glucose, plasma proteins, and squamous cell lung cancer
inferred← citeshttps://doi.org/10.1007/s12672-025-02760-4openalex-snapshot
Assessing the influence of metabolic syndrome on thyroid cancer: insights from a Mendelian randomization approach
inferred← citeshttps://doi.org/10.1007/s13668-014-0100-8openalex-snapshot
Gene-Lifestyle Interactions in Complex Diseases: Design and Description of the GLACIER and VIKING Studies
inferred← citeshttps://doi.org/10.1007/s13679-013-0086-3openalex-snapshot
Findings from the Quebec Family Study on the Etiology of Obesity: Genetics and Environmental Highlights
inferred← citeshttps://doi.org/10.1007/s40520-015-0370-zopenalex-snapshot
A Chromosome 13 locus is associated with male-specific mortality in mice
inferred← citeshttps://doi.org/10.1016/b978-0-12-799961-6.00006-8openalex-snapshot
Discovery of High-Density Lipoprotein Gene Targets from Classical Genetics to Genome-Wide Association Studies
inferred← citeshttps://doi.org/10.1016/b978-0-12-802928-2.00029-1openalex-snapshot
Genetics and Diabetes
inferred← citeshttps://doi.org/10.1016/b978-0-12-811060-7.00017-6openalex-snapshot
The Role of Epigenetic Modifications in Cardiometabolic Diseases
inferred← citeshttps://doi.org/10.1016/b978-0-12-812626-4.00009-7openalex-snapshot
The Role of Pharmacogenomics in Diabetes
inferred← citeshttps://doi.org/10.1016/b978-0-12-814259-2.00012-1openalex-snapshot
Chromatin landscape and epigenetic biomarkers for clinical diagnosis and prognosis of type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.1016/b978-0-323-29738-7.00031-9openalex-snapshot
Type 2 Diabetes Mellitus
inferred← citeshttps://doi.org/10.1016/b978-0-323-58131-8.00001-xopenalex-snapshot
A Summary of Recent Updates on the Genetic Determinants of Depression
inferred← citeshttps://doi.org/10.1016/b978-0-323-99892-5.00020-7openalex-snapshot
iPSCs in insulin resistance, type 2 diabetes, and the metabolic syndrome
inferred← citeshttps://doi.org/10.1016/b978-0-443-11985-9.00015-9openalex-snapshot
Genetics of Type 2 Diabetes
inferred← citeshttps://doi.org/10.1016/b978-1-4377-0324-5.00031-6openalex-snapshot
Type 2 Diabetes Mellitus
inferred← citeshttps://doi.org/10.1016/bs.adgen.2024.03.001openalex-snapshot
Host genetics and nutrition
inferred← citeshttps://doi.org/10.1016/j.ajhg.2014.03.004openalex-snapshot
Joint Analysis of Functional Genomic Data and Genome-wide Association Studies of 18 Human Traits
inferred← citeshttps://doi.org/10.1016/j.ajhg.2014.12.021openalex-snapshot
Adjusting for Heritable Covariates Can Bias Effect Estimates in Genome-Wide Association Studies
inferred← citeshttps://doi.org/10.1016/j.ajhg.2016.05.006openalex-snapshot
Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin
inferred← citeshttps://doi.org/10.1016/j.ajhg.2016.07.001openalex-snapshot
Adiposity-Dependent Regulatory Effects on Multi-tissue Transcriptomes
inferred← citeshttps://doi.org/10.1016/j.ajhg.2017.01.027openalex-snapshot
Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits
inferred← citeshttps://doi.org/10.1016/j.ajhg.2017.11.001openalex-snapshot
A Powerful Approach to Estimating Annotation-Stratified Genetic Covariance via GWAS Summary Statistics
inferred← citeshttps://doi.org/10.1016/j.ajhg.2018.01.015openalex-snapshot
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
inferred← citeshttps://doi.org/10.1016/j.ajhg.2018.03.026openalex-snapshot
FUN-LDA: A Latent Dirichlet Allocation Model for Predicting Tissue-Specific Functional Effects of Noncoding Variation: Methods and Applications
inferred← citeshttps://doi.org/10.1016/j.ajhg.2018.12.001openalex-snapshot
Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits
inferred← citeshttps://doi.org/10.1016/j.ajhg.2019.05.002openalex-snapshot
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology
inferred← citeshttps://doi.org/10.1016/j.ajhg.2021.02.008openalex-snapshot
Mendelian pathway analysis of laboratory traits reveals distinct roles for ciliary subcompartments in common disease pathogenesis
inferred← citeshttps://doi.org/10.1016/j.ajhg.2024.03.014openalex-snapshot
A new test for trait mean and variance detects unreported loci for blood-pressure variation
inferred← citeshttps://doi.org/10.1016/j.ajhg.2025.11.006openalex-snapshot
Improving polygenic risk prediction performance by integrating electronic health records through phenotype embedding
inferred← citeshttps://doi.org/10.1016/j.annepidem.2016.03.001openalex-snapshot
Increased cardiovascular risks associated with familial inbreeding: a population-based study of adolescent cohort
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2013.03.037openalex-snapshot
Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2014.10.005openalex-snapshot
Joint effect of insulin signaling genes on all-cause mortality
inferred← citeshttps://doi.org/10.1016/j.bbadis.2014.04.025openalex-snapshot
Systems genetics: From GWAS to disease pathways
inferred← citeshttps://doi.org/10.1016/j.bcp.2012.09.019openalex-snapshot
High-carbohydrate diets induce hepatic insulin resistance to protect the liver from substrate overload
inferred← citeshttps://doi.org/10.1016/j.bcp.2014.08.002openalex-snapshot
Zinc: An underappreciated modulatory factor of brain function
inferred← citeshttps://doi.org/10.1016/j.bpsgos.2021.06.005openalex-snapshot
Genetic Liability to Cannabis Use Disorder and COVID-19 Hospitalization
inferred← citeshttps://doi.org/10.1016/j.bpsgos.2025.100678openalex-snapshot
Exploring the Genetic Overlap Between Metabolic Traits and Anorexia Nervosa
inferred← citeshttps://doi.org/10.1016/j.canlet.2012.09.017openalex-snapshot
Cancer genetics and genomics of human FOX family genes
inferred← citeshttps://doi.org/10.1016/j.cell.2016.09.037openalex-snapshot
Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters
inferred← citeshttps://doi.org/10.1016/j.cell.2021.10.024openalex-snapshot
A single-cell atlas of chromatin accessibility in the human genome
inferred← citeshttps://doi.org/10.1016/j.cellsig.2015.01.003openalex-snapshot
Insulin-induced cell division is controlled by the adaptor Grb14 in a Chfr-dependent manner
inferred← citeshttps://doi.org/10.1016/j.celrep.2016.05.056openalex-snapshot
FOXN3 Regulates Hepatic Glucose Utilization
inferred← citeshttps://doi.org/10.1016/j.celrep.2018.06.039openalex-snapshot
A Hepatocyte FOXN3-α Cell Glucagon Axis Regulates Fasting Glucose
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.08.066openalex-snapshot
The Protein Phosphatase 1 Complex Is a Direct Target of AKT that Links Insulin Signaling to Hepatic Glycogen Deposition
inferred← citeshttps://doi.org/10.1016/j.celrep.2026.118042openalex-snapshot
Transcriptional and epigenomic analysis of insulin sensitivity in human adipocytes
inferred← citeshttps://doi.org/10.1016/j.cels.2016.10.004openalex-snapshot
Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome
inferred← citeshttps://doi.org/10.1016/j.clnu.2020.09.018openalex-snapshot
Impact of urinary sodium on cardiovascular disease and risk factors: A 2 sample Mendelian randomization study
inferred← citeshttps://doi.org/10.1016/j.cmet.2013.05.002openalex-snapshot
RETRACTED: The Cancer-Associated FGFR4-G388R Polymorphism Enhances Pancreatic Insulin Secretion and Modifies the Risk of Diabetes
inferred← citeshttps://doi.org/10.1016/j.cmet.2015.01.009openalex-snapshot
LRP5 Regulates Human Body Fat Distribution by Modulating Adipose Progenitor Biology in a Dose- and Depot-Specific Fashion
inferred← citeshttps://doi.org/10.1016/j.cmet.2016.04.002openalex-snapshot
Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function
inferred← citeshttps://doi.org/10.1016/j.cmet.2017.04.009openalex-snapshot
FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans
inferred← citeshttps://doi.org/10.1016/j.cmet.2021.01.001openalex-snapshot
A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density
inferred← citeshttps://doi.org/10.1016/j.coph.2017.08.007openalex-snapshot
Catching new targets in metabolic disease with a zebrafish
inferred← citeshttps://doi.org/10.1016/j.ddmec.2013.05.003openalex-snapshot
The genetic influence on body fat distribution
inferred← citeshttps://doi.org/10.1016/j.diabres.2017.02.013openalex-snapshot
Replication of newly identified type 2 diabetes susceptible loci in Northwest Indian population
inferred← citeshttps://doi.org/10.1016/j.dsx.2022.102675openalex-snapshot
Genetic predisposition to gestational diabetes mellitus in the Kazakh population
inferred← citeshttps://doi.org/10.1016/j.ebiom.2018.07.037openalex-snapshot
Glucose and Insulin-Related Traits, Type 2 Diabetes and Risk of Schizophrenia: A Mendelian Randomization Study
inferred← citeshttps://doi.org/10.1016/j.ebiom.2019.02.021openalex-snapshot
Evaluation of GDF15 as a therapeutic target of cardiometabolic diseases in human: A Mendelian randomization study
inferred← citeshttps://doi.org/10.1016/j.ebiom.2019.03.051openalex-snapshot
A biologically-informed polygenic score identifies endophenotypes and clinical conditions associated with the insulin receptor function on specific brain regions
inferred← citeshttps://doi.org/10.1016/j.ebiom.2020.103062openalex-snapshot
Meta-analysis investigating the role of interleukin-6 mediated inflammation in type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.envint.2016.04.032openalex-snapshot
Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score
inferred← citeshttps://doi.org/10.1016/j.exger.2014.03.022openalex-snapshot
mtDNA mutations in human aging and longevity: Controversies and new perspectives opened by high-throughput technologies
inferred← citeshttps://doi.org/10.1016/j.exphem.2017.07.007openalex-snapshot
Genetic risk of prediabetes and diabetes development in chronic myeloid leukemia patients treated with nilotinib
inferred← citeshttps://doi.org/10.1016/j.gdata.2015.12.001openalex-snapshot
Transcriptomics in type 2 diabetes: Bridging the gap between genotype and phenotype
inferred← citeshttps://doi.org/10.1016/j.gde.2018.02.002openalex-snapshot
Genetic syndromes of severe insulin resistance
inferred← citeshttps://doi.org/10.1016/j.gendis.2025.101972openalex-snapshot
FOXA2 in islet biology: Orchestrating pancreatic development and glucose homeostasis
inferred← citeshttps://doi.org/10.1016/j.gene.2020.144722openalex-snapshot
Genetics of type 2 diabetes and coronary artery disease and their associations with twelve cardiometabolic traits in the United Arab Emirates population
inferred← citeshttps://doi.org/10.1016/j.ijcard.2016.04.079openalex-snapshot
Alpha2A adrenergic receptor genetic variation contributes to hyperglycemia after myocardial infarction
inferred← citeshttps://doi.org/10.1016/j.jacc.2019.08.1055openalex-snapshot
Genome-Wide Assessment for Resting Heart Rate and Shared Genetics With Cardiometabolic Traits and Type 2 Diabetes
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2026.142905openalex-snapshot
Genome-wide interactions with cadmium exposure in dysglycemia: Populational effects and molecular insights
inferred← citeshttps://doi.org/10.1016/j.jhep.2020.03.006openalex-snapshot
Causal relationships between NAFLD, T2D and obesity have implications for disease subphenotyping
inferred← citeshttps://doi.org/10.1016/j.jlr.2026.101013openalex-snapshot
LYPLAL1 rare loss-of-function variants in humans and deletion in human hepatoma cells protect against MASLD
inferred← citeshttps://doi.org/10.1016/j.jmb.2015.07.003openalex-snapshot
Post-Transcriptional Regulation of Renalase Gene by miR-29 and miR-146 MicroRNAs: Implications for Cardiometabolic Disorders
inferred← citeshttps://doi.org/10.1016/j.joca.2012.08.007openalex-snapshot
Osteoarthritis year 2012 in review: genetics and genomics
inferred← citeshttps://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107392openalex-snapshot
Candidate genes related to acute cerebral circulatory disorders in Preeclampsia in the Kazakh Population
inferred← citeshttps://doi.org/10.1016/j.livsci.2022.105048openalex-snapshot
Estimates of heritability and candidate genes for primal cuts and dressing percentage in Santa Ines sheep
inferred← citeshttps://doi.org/10.1016/j.metabol.2018.02.008openalex-snapshot
Metabolic syndrome and uric acid nephrolithiasis: insulin resistance in focus
inferred← citeshttps://doi.org/10.1016/j.metabol.2021.154892openalex-snapshot
Insulin resistance and insulin sensitizing agents
inferred← citeshttps://doi.org/10.1016/j.metabol.2024.156112openalex-snapshot
Shared genetic architecture of type 2 diabetes with muscle mass and function and frailty reveals comorbidity etiology and pleiotropic druggable targets
inferred← citeshttps://doi.org/10.1016/j.molmet.2018.10.006openalex-snapshot
An in vivo screen for neuronal genes involved in obesity identifies Diacylglycerol kinase as a regulator of insulin secretion
inferred← citeshttps://doi.org/10.1016/j.molmet.2019.03.001openalex-snapshot
Discovering metabolic disease gene interactions by correlated effects on cellular morphology
inferred← citeshttps://doi.org/10.1016/j.molmet.2020.101041openalex-snapshot
Regulation of inflammation in diabetes: From genetics to epigenomics evidence
inferred← citeshttps://doi.org/10.1016/j.molmet.2021.101388openalex-snapshot
Targeting the cytoplasmic polyadenylation element-binding protein CPEB4 protects against diet-induced obesity and microbiome dysbiosis
inferred← citeshttps://doi.org/10.1016/j.numecd.2013.05.001openalex-snapshot
The SH2B1 obesity locus and abnormal glucose homeostasis: Lack of evidence for association from a meta-analysis in individuals of European ancestry
inferred← citeshttps://doi.org/10.1016/j.numecd.2016.04.002openalex-snapshot
The role of global and regional DNA methylation and histone modifications in glycemic traits and type 2 diabetes: A systematic review
inferred← citeshttps://doi.org/10.1016/j.numecd.2017.10.012openalex-snapshot
Interrelationship of the rs7903146 TCF7L2 gene variant with measures of glucose metabolism and adiposity: The NEO study
inferred← citeshttps://doi.org/10.1016/j.numecd.2023.01.011openalex-snapshot
Genetic prediction of age at menarche, age at natural menopause and type 2 diabetes: A Mendelian randomization study
inferred← citeshttps://doi.org/10.1016/j.nutres.2023.08.008openalex-snapshot
Influence of polymorphisms in IRS1, IRS2, MC3R, and MC4R on metabolic and inflammatory status and food intake in Brazilian adults: An exploratory pilot study
inferred← citeshttps://doi.org/10.1016/j.pharma.2012.07.001openalex-snapshot
Diabésité et maladies cardiovasculaires : nouveaux médiateurs et nouvelles cibles
inferred← citeshttps://doi.org/10.1016/j.schres.2017.10.033openalex-snapshot
Genetically determined schizophrenia is not associated with impaired glucose homeostasis
inferred← citeshttps://doi.org/10.1016/j.taap.2018.03.034openalex-snapshot
Arsenic-gene interactions and beta-cell function in the Strong Heart Family Study
inferred← citeshttps://doi.org/10.1016/j.tips.2015.04.010openalex-snapshot
Targeting SREBPs for treatment of the metabolic syndrome
inferred← citeshttps://doi.org/10.1016/j.toxrep.2020.09.011openalex-snapshot
Acetylator Genotype-Dependent Dyslipidemia in Rats Congenic for N-Acetyltransferase 2
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