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Calmodulin kinase II inhibition protects against structural heart disease

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1 of the 51 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-21): 10.1038/35004052 (notice 2015-03-27).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1006/jmcc.1997.0508openalex-snapshot

Effects of Chronicβ-Adrenergic Receptor Stimulation in Mice

inferredcites →https://doi.org/10.1016/s0021-9258(17)31500-4openalex-snapshot

Discrimination between two sites of phosphorylation on adjacent amino acids by phosphorylation site-specific antibodies to phospholamban.

inferredcites →https://doi.org/10.1016/s0026-895x(25)14991-2openalex-snapshot

Activation of calmodulin by various metal cations as a function of ionic radius.

inferredcites →https://doi.org/10.1016/s0092-8674(00)80847-8openalex-snapshot

PKA Phosphorylation Dissociates FKBP12.6 from the Calcium Release Channel (Ryanodine Receptor)

inferredcites →https://doi.org/10.1016/s0140-6736(99)04440-2openalex-snapshot

Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in-Congestive Heart Failure (MERIT-HF)

inferredcites →https://doi.org/10.1016/s0735-1097(97)00012-0openalex-snapshot

Left Ventricular Remodeling With Carvedilol in Patients With Congestive Heart Failure Due to Ischemic Heart Disease fn1fn1This study was funded by a grant from SmithKline Beecham; however, the study was initiated, conducted, analyzed and reported by the Australia–New Zealand Heart Failure Research…

inferredcites →https://doi.org/10.1016/s0896-6273(00)80358-xopenalex-snapshot

cAMP-Dependent Regulation of Cardiac L-Type Ca2+ Channels Requires Membrane Targeting of PKA and Phosphorylation of Channel Subunits

inferredcites →https://doi.org/10.1038/35004052openalex-snapshot

Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels

inferredcites →https://doi.org/10.1038/415198aopenalex-snapshot

Cardiac excitation–contraction coupling

inferredcites →https://doi.org/10.1038/74914openalex-snapshot

Transgenic expression of green fluorescence protein can cause dilated cardiomyopathy

inferredcites →https://doi.org/10.1038/ncb0802-e203openalex-snapshot

Kinase- and phosphatase-anchoring proteins: harnessing the dynamic duo

inferredcites →https://doi.org/10.1038/nrd773openalex-snapshot

Protein kinases — the major drug targets of the twenty-first century?

inferredcites →https://doi.org/10.1042/bj20020228openalex-snapshot

Structure–function of the multifunctional Ca2+/calmodulin-dependent protein kinase II

inferredcites →https://doi.org/10.1042/bj20031043openalex-snapshot

Calcium/calmodulin-dependent protein kinase IIdelta associates with the ryanodine receptor complex and regulates channel function in rabbit heart

inferredcites →https://doi.org/10.1056/nejmra021498openalex-snapshot

Heart Failure

inferredcites →https://doi.org/10.1067/s0894-7317(03)00471-1openalex-snapshot

Temporal changes in ventricular function assessed echocardiographically in conscious and anesthetized mice

inferredcites →https://doi.org/10.1073/pnas.051449198openalex-snapshot

Calmodulin kinase is a molecular switch for cardiac excitation –contraction coupling

inferredcites →https://doi.org/10.1073/pnas.262372999openalex-snapshot

Engineered calmodulins reveal the unexpected eminence of Ca 2+ channel inactivation in controlling heart excitation

inferredcites →https://doi.org/10.1073/pnas.87.2.753openalex-snapshot

Beta-adrenergic stimulation of calcium channels occurs by potentiation of high-activity gating modes.

inferredcites →https://doi.org/10.1073/pnas.91.20.9659openalex-snapshot

Dual regulation of Ca2+/calmodulin-dependent kinase II activity by membrane voltage and by calcium influx.

inferredcites →https://doi.org/10.1074/jbc.272.49.31203openalex-snapshot

The Nuclear δB Isoform of Ca2+/Calmodulin-dependent Protein Kinase II Regulates Atrial Natriuretic Factor Gene Expression in Ventricular Myocytes

inferredcites →https://doi.org/10.1074/jbc.275.4.2532openalex-snapshot

Distinct Roles for the Helicases of TFIIH in Transcript Initiation and Promoter Escape

inferredcites →https://doi.org/10.1074/jbc.c000253200openalex-snapshot

Frequency-encoding Thr17 Phospholamban Phosphorylation Is Independent of Ser16 Phosphorylation in Cardiac Myocytes

inferredcites →https://doi.org/10.1074/jbc.c301180200openalex-snapshot

Stoichiometric Phosphorylation of Cardiac Ryanodine Receptor on Serine 2809 by Calmodulin-dependent Kinase II and Protein Kinase A

inferredcites →https://doi.org/10.1074/jbc.m004079200openalex-snapshot

A Single Site (Ser16) Phosphorylation in Phospholamban Is Sufficient in Mediating Its Maximal Cardiac Responses to β-Agonists

inferredcites →https://doi.org/10.1074/jbc.m209532200openalex-snapshot

The Nature of the Arrestin·Receptor Complex Determines the Ultimate Fate of the Internalized Receptor

inferredcites →https://doi.org/10.1085/jgp.98.2.265openalex-snapshot

Properties of L-type calcium channel gating current in isolated guinea pig ventricular myocytes.

inferredcites →https://doi.org/10.1111/j.1469-7793.2001.0201b.xopenalex-snapshot

Alterations in action potential profile enhance excitation‐contraction coupling in rat cardiac myocytes

inferredcites →https://doi.org/10.1113/jphysiol.1975.sp011026openalex-snapshot

Contractions induced by a calcium‐triggered release of calcium from the sarcoplasmic reticulum of single skinned cardiac cells.

inferredcites →https://doi.org/10.1113/jphysiol.1995.sp020944openalex-snapshot

A non‐selective cation current activated via the multifunctional Ca(2+)‐calmodulin‐dependent protein kinase in human epithelial cells.

inferredcites →https://doi.org/10.1126/science.276.5313.800openalex-snapshot

Defective Excitation-Contraction Coupling in Experimental Cardiac Hypertrophy and Heart Failure

inferredcites →https://doi.org/10.1126/science.8235594openalex-snapshot

Calcium Sparks: Elementary Events Underlying Excitation-Contraction Coupling in Heart Muscle

inferredcites →https://doi.org/10.1152/ajpheart.1994.267.3.h982openalex-snapshot

Ca-dependent facilitation of cardiac Ca current is due to Ca-calmodulin-dependent protein kinase

inferredcites →https://doi.org/10.1152/ajpheart.1998.274.3.h829openalex-snapshot

Optical mapping of atrioventricular node reveals a conduction barrier between atrial and nodal cells

inferredcites →https://doi.org/10.1152/ajplegacy.1911.28.1.64openalex-snapshot

EMOTIONAL STIMULATION OF ADRENAL SECRETION

inferredcites →https://doi.org/10.1161/01.cir.0000027583.73268.e7openalex-snapshot

Calmodulin Kinase II and Arrhythmias in a Mouse Model of Cardiac Hypertrophy

inferredcites →https://doi.org/10.1161/01.cir.0000033826.52681.37openalex-snapshot

Targeted Deletion of Angiotensin II Type 2 Receptor Caused Cardiac Rupture After Acute Myocardial Infarction

inferredcites →https://doi.org/10.1161/01.cir.103.1.140openalex-snapshot

A Ca 2+ -Dependent Transgenic Model of Cardiac Hypertrophy

inferredcites →https://doi.org/10.1161/01.cir.94.4.690openalex-snapshot

Prognostic Significance of Plasma Norepinephrine in Patients With Asymptomatic Left Ventricular Dysfunction

inferredcites →https://doi.org/10.1161/01.res.0000069685.20258.f1openalex-snapshot

Transgenic CaMKIIδ C Overexpression Uniquely Alters Cardiac Myocyte Ca 2+ Handling

inferredcites →https://doi.org/10.1161/01.res.0000069686.31472.c5openalex-snapshot

The δ C Isoform of CaMKII Is Activated in Cardiac Hypertrophy and Induces Dilated Cardiomyopathy and Heart Failure

inferredcites →https://doi.org/10.1161/01.res.0000070595.10196.cfopenalex-snapshot

Signal Transduction and Ca 2+ Signaling in Contractile Regulation Induced by Crosstalk Between Endothelin-1 and Norepinephrine in Dog Ventricular Myocardium

inferredcites →https://doi.org/10.1161/01.res.0000088785.24381.2fopenalex-snapshot

Cardiac Memory Is Associated With Decreased Levels of the Transcriptional Factor CREB Modulated by Angiotensin II and Calcium

inferredcites →https://doi.org/10.1161/01.res.0000125626.33738.e2openalex-snapshot

Ca 2+ /Calmodulin-Dependent Protein Kinase II Phosphorylation Regulates the Cardiac Ryanodine Receptor

inferredcites →https://doi.org/10.1161/01.res.61.1.70openalex-snapshot

Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure.

inferredcites →https://doi.org/10.1161/01.res.65.3.657openalex-snapshot

Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis.

inferredcites →https://doi.org/10.1161/01.res.75.5.854openalex-snapshot

Multifunctional Ca2+/calmodulin-dependent protein kinase mediates Ca(2+)-induced enhancement of the L-type Ca2+ current in rabbit ventricular myocytes.

inferredcites →https://doi.org/10.1161/01.res.84.6.713openalex-snapshot

Identification and Expression of δ-Isoforms of the Multifunctional Ca 2+ /Calmodulin-Dependent Protein Kinase in Failing and Nonfailing Human Myocardium

inferredcites →https://doi.org/10.1161/01.res.85.12.1139openalex-snapshot

Aldosterone Upregulates Ca2+Current in Adult Rat Cardiomyocytes

inferredcites →https://doi.org/10.1161/01.res.87.9.760openalex-snapshot

Sinoatrial Node Pacemaker Activity Requires Ca2+/Calmodulin-Dependent Protein Kinase II Activation

inferredcites →https://doi.org/10.1172/jci16326openalex-snapshot

Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4636708openalex-extracted

Loss Of Beta2-Adrenoceptor Triggers Ca v1.2-CaNKII-Dependent Inflammation and Fibrosis in the Heart

inferred← citeshttps://doi.org/10.1001/jamacardio.2021.0701openalex-snapshot

To Be or Not to Be a CaMKII Inhibitor?

inferred← citeshttps://doi.org/10.1001/jamacardio.2023.0983openalex-snapshot

CRISPR Editing Takes Aim at Ischemia/Reperfusion Injury

inferred← citeshttps://doi.org/10.1002/9780470561416.ch12openalex-snapshot

Calcium/Calmodulin‐Dependent Protein Kinase II (CaMKII)—Modulation of Ion Currents and Potential Role for Arrhythmias

inferred← citeshttps://doi.org/10.1002/9780470561416.ch21openalex-snapshot

Dietary Omega‐3 Fatty Acids as a Nonpharmacological Antiarrhythmic Intervention

inferred← citeshttps://doi.org/10.1002/9780470571224.pse449openalex-snapshot

Cardiology—In‐Depth Look: Kinases as Therapeutic Targets in the Heart

inferred← citeshttps://doi.org/10.1002/9780470872390.refsopenalex-snapshot

References

inferred← citeshttps://doi.org/10.1002/9781118493038.ch3openalex-snapshot

Protein Oxidation and Aging: Different Model Systems and Affecting Factors

inferred← citeshttps://doi.org/10.1002/adfm.202425206openalex-snapshot

Defect Engineering of Layered Double Hydroxide Nanosheets as Inorganic Photosensitizers for NIR‐II Photodynamic Hypertrophic Cardiomyopathy Therapy

inferred← citeshttps://doi.org/10.1002/cbdv.202200309openalex-snapshot

Cardioprotective Effect of Polymyxin‐B and Dantrolene Combination on Isoproterenol‐Induced Hypertrophic Cardiomyopathy in Rats, via Attenuation of Calmodulin‐Dependent Protein Kinase II

inferred← citeshttps://doi.org/10.1002/ctm2.70432openalex-snapshot

Reversing cardiac hypertrophy and heart failure using a cardiac targeting peptide linked to miRNA106a

inferred← citeshttps://doi.org/10.1002/ejhf.204openalex-snapshot

CaMKII Confirms its Promise in Ischaemic Heart Disease

inferred← citeshttps://doi.org/10.1002/path.4594openalex-snapshot

Deletion of low molecular weight protein tyrosine phosphatase (Acp1) protects against stress‐induced cardiomyopathy

inferred← citeshttps://doi.org/10.1002/prot.22317openalex-snapshot

Energetics of calmodulin domain interactions with the calmodulin binding domain of CaMKII

inferred← citeshttps://doi.org/10.1002/ptr.5787openalex-snapshot

Four Main Active Ingredients Derived from a Traditional Chinese Medicine Guanxin Shutong Capsule Cause Cardioprotection during Myocardial Ischemia Injury Calcium Overload Suppression

inferred← citeshttps://doi.org/10.1007/978-1-4419-9461-5_21openalex-snapshot

Targeting Signaling Pathways

inferred← citeshttps://doi.org/10.1007/978-1-4614-5203-4_24openalex-snapshot

The Role of CaM Kinase II in Cardiac Function in Health and Disease

inferred← citeshttps://doi.org/10.1007/978-1-4614-7678-8_2openalex-snapshot

Sarcoplasmic Reticulum Ca Homeostasis and Heart Failure

inferred← citeshttps://doi.org/10.1007/978-1-4614-9469-0_1openalex-snapshot

Anatomy of the Cardiovascular Apparatus

inferred← citeshttps://doi.org/10.1007/978-1-4614-9469-0_2openalex-snapshot

Anatomy of the Ventilatory Apparatus

inferred← citeshttps://doi.org/10.1007/978-1-4614-9469-0_3openalex-snapshot

Cardiovascular Physiology

inferred← citeshttps://doi.org/10.1007/978-1-4614-9469-0_4openalex-snapshot

Physiology of Ventilation

inferred← citeshttps://doi.org/10.1007/978-1-4614-9469-0_5openalex-snapshot

Medical Images and Physiological Signals

inferred← citeshttps://doi.org/10.1007/978-3-030-12457-1_21openalex-snapshot

Widespread Roles of CaMK-II in Developmental Pathways

inferred← citeshttps://doi.org/10.1007/978-3-031-08309-9_3openalex-snapshot

Stress Kinase Signaling in Cardiac Myocytes

inferred← citeshttps://doi.org/10.1007/978-3-031-33588-4_22openalex-snapshot

Calmodulin Kinase II Regulation of Heart Rhythm and Disease

inferred← citeshttps://doi.org/10.1007/978-3-642-17575-6_19openalex-snapshot

Calmodulin Kinase II Regulation of Heart Rhythm and Disease

inferred← citeshttps://doi.org/10.1007/978-3-642-37078-6_23openalex-snapshot

Physiology and Pathophysiology of Macrocirculation

inferred← citeshttps://doi.org/10.1007/978-3-642-37078-6_33openalex-snapshot

Computational Fluid Dynamics and Cerebral Aneurysms

inferred← citeshttps://doi.org/10.1007/978-3-642-37393-0_23-1openalex-snapshot

Macrocirculation

inferred← citeshttps://doi.org/10.1007/978-94-007-2888-2_30openalex-snapshot

Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) in the Heart

inferred← citeshttps://doi.org/10.1007/978-94-007-2888-2_52openalex-snapshot

Remodeling of Calcium Handling in Human Heart Failure

inferred← citeshttps://doi.org/10.1007/s00018-013-1516-9openalex-snapshot

Histone deacetylase signaling in cardioprotection

inferred← citeshttps://doi.org/10.1007/s00018-023-05037-7openalex-snapshot

JOSD2 mediates isoprenaline-induced heart failure by deubiquitinating CaMKIIδ in cardiomyocytes

inferred← citeshttps://doi.org/10.1007/s00109-006-0125-6openalex-snapshot

CaMKII, an emerging molecular driver for calcium homeostasis, arrhythmias, and cardiac dysfunction

inferred← citeshttps://doi.org/10.1007/s00109-010-0646-xopenalex-snapshot

Complex role of the HIF system in cardiovascular biology

inferred← citeshttps://doi.org/10.1007/s00109-011-0727-5openalex-snapshot

Is CaMKII a link between inflammation and hypertrophy in heart?

inferred← citeshttps://doi.org/10.1007/s00210-013-0873-0openalex-snapshot

Vitexin protects against cardiac hypertrophy via inhibiting calcineurin and CaMKII signaling pathways

inferred← citeshttps://doi.org/10.1007/s00395-013-0360-2openalex-snapshot

Novel aspects of excitation–contraction coupling in heart failure

inferred← citeshttps://doi.org/10.1007/s00395-016-0581-2openalex-snapshot

Inducible cardiomyocyte-specific deletion of CaM kinase II protects from pressure overload-induced heart failure

inferred← citeshttps://doi.org/10.1007/s00395-018-0688-8openalex-snapshot

Physiological and unappreciated roles of CaMKII in the heart

inferred← citeshttps://doi.org/10.1007/s00421-011-1994-0openalex-snapshot

Chronic CaMKII inhibition blunts the cardiac contractile response to exercise training

inferred← citeshttps://doi.org/10.1007/s00424-013-1326-9openalex-snapshot

Adult cardiac fibroblast proliferation is modulated by calcium/calmodulin-dependent protein kinase II in normal and hypertrophied hearts

inferred← citeshttps://doi.org/10.1007/s00424-014-1462-xopenalex-snapshot

Heart failure-specific changes in protein kinase signalling

inferred← citeshttps://doi.org/10.1007/s00424-014-1469-3openalex-snapshot

Ca handling during excitation–contraction coupling in heart failure

inferred← citeshttps://doi.org/10.1007/s00424-018-2122-3openalex-snapshot

The role of RyR2 oxidation in the blunted frequency-dependent facilitation of Ca2+ transient amplitude in rabbit failing myocytes

inferred← citeshttps://doi.org/10.1007/s00424-021-02533-2openalex-snapshot

Stress-driven cardiac calcium mishandling via a kinase-to-kinase crosstalk

inferred← citeshttps://doi.org/10.1007/s00441-014-1887-8openalex-snapshot

Epigenetics in cardiac development, function, and disease

inferred← citeshttps://doi.org/10.1007/s10741-015-9498-3openalex-snapshot

The role of CaMKII in diabetic heart dysfunction

inferred← citeshttps://doi.org/10.1007/s11010-013-1918-xopenalex-snapshot

Mitigation of postischemic cardiac contractile dysfunction by CaMKII inhibition: effects on programmed necrotic and apoptotic cell death

inferred← citeshttps://doi.org/10.1007/s11427-025-2939-1openalex-snapshot

Danhong Injection targets CaMKII through Dihydrotanshinone I to alleviate cardiomyocyte death and inflammation in viral myocarditis

inferred← citeshttps://doi.org/10.1007/s11626-017-0215-5openalex-snapshot

Klotho attenuates isoproterenol-induced hypertrophic response in H9C2 cells by activating Na+/K+-ATPase and inhibiting the reverse mode of Na+/Ca2+-exchanger

inferred← citeshttps://doi.org/10.1007/s11897-007-0020-7openalex-snapshot

Remodeling of excitation-contraction coupling in the heart: Inhibition of sarcoplasmic reticulum Ca2+ leak as a novel therapeutic approach

inferred← citeshttps://doi.org/10.1007/s12265-013-9503-yopenalex-snapshot

Hypertrophy Signaling Pathways in Experimental Chronic Aortic Regurgitation

inferred← citeshttps://doi.org/10.1007/s12350-015-0078-7openalex-snapshot

Large Animal Models of Ischemic Cardiomyopathy: Are They Enough to Bridge the Translational Gap?

inferred← citeshttps://doi.org/10.1007/s12471-017-0946-7openalex-snapshot

Potential new mechanisms of pro-arrhythmia in arrhythmogenic cardiomyopathy: focus on calcium sensitive pathways

inferred← citeshttps://doi.org/10.1007/s12551-020-00742-0openalex-snapshot

The molecular mechanisms associated with the physiological responses to inflammation and oxidative stress in cardiovascular diseases

inferred← citeshttps://doi.org/10.1016/b978-0-12-381510-1.00008-9openalex-snapshot

G-Protein-Coupled Receptors in the Heart

inferred← citeshttps://doi.org/10.1016/b978-0-12-384921-2.00009-4openalex-snapshot

β-Adrenergic Receptor Subtype Signaling in the Heart: from Bench to the Bedside

inferred← citeshttps://doi.org/10.1016/b978-0-12-800040-3.00003-0openalex-snapshot

Molecular Pathways in Cardiomyopathies

inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.99834-9openalex-snapshot

OBSOLETE: Cardiac Hypertrophy: Signaling and Cellular Crosstalk

inferred← citeshttps://doi.org/10.1016/b978-0-12-809657-4.99834-xopenalex-snapshot

Cardiac Hypertrophy: Signaling and Cellular Crosstalk

inferred← citeshttps://doi.org/10.1016/b978-0-323-60987-6.00006-5openalex-snapshot

Adrenergic Receptor Signaling in Heart Failure

inferred← citeshttps://doi.org/10.1016/b978-0-443-15734-9.00070-4openalex-snapshot

Cardiac Hypertrophy: Signaling and Cellular Crosstalk

inferred← citeshttps://doi.org/10.1016/b978-1-4160-3291-5.50029-9openalex-snapshot

RHYTHM DISORDERS

inferred← citeshttps://doi.org/10.1016/b978-1-4160-5895-3.10002-6openalex-snapshot

Molecular Basis for Heart Failure

inferred← citeshttps://doi.org/10.1016/b978-1-4160-5895-3.10010-5openalex-snapshot

Activation of the Adrenergic Nervous System in Heart Failure

inferred← citeshttps://doi.org/10.1016/b978-1-4557-2856-5.00037-6openalex-snapshot

CaV1.2 and β-Adrenergic Regulation of Cardiac Function

inferred← citeshttps://doi.org/10.1016/b978-1-4557-2856-5.00112-6openalex-snapshot

New Antiarrhythmic Drugs and New Concepts for Old Drugs

inferred← citeshttps://doi.org/10.1016/j.abb.2010.11.008openalex-snapshot

Kinetic mechanisms of Ca++/calmodulin dependent protein kinases

inferred← citeshttps://doi.org/10.1016/j.arr.2025.102886openalex-snapshot

Ca2+/Calmodulin-dependent protein kinase II (CaMKII)-targeted drug discovery: Challenges and strategies

inferred← citeshttps://doi.org/10.1016/j.bbadis.2013.06.008openalex-snapshot

Alterations in ryanodine receptors and related proteins in heart failure

inferred← citeshttps://doi.org/10.1016/j.bbadis.2020.165729openalex-snapshot

CaMKII and GLUT1 in heart failure and the role of gliflozins

inferred← citeshttps://doi.org/10.1016/j.bbalip.2022.159120openalex-snapshot

Ca2+/calmodulin-dependent protein kinase II inhibition reduces myocardial fatty acid uptake and oxidation after myocardial infarction

inferred← citeshttps://doi.org/10.1016/j.bbamcr.2012.08.016openalex-snapshot

Posttranslational modifications of cardiac ryanodine receptors: Ca2+ signaling and EC-coupling

inferred← citeshttps://doi.org/10.1016/j.bbamem.2007.02.010openalex-snapshot

Cardiac GPCRs: GPCR signaling in healthy and failing hearts

inferred← citeshttps://doi.org/10.1016/j.bbrc.2007.02.087openalex-snapshot

Oxidation of calmodulin alters activation and regulation of CaMKII

inferred← citeshttps://doi.org/10.1016/j.bbrc.2007.10.082openalex-snapshot

Calcium, troponin, calmodulin, S100 proteins: From myocardial basics to new therapeutic strategies

inferred← citeshttps://doi.org/10.1016/j.bbrc.2022.04.082openalex-snapshot

CaMKII inhibition protects against hyperthyroid arrhythmias and adverse myocardial remodeling

inferred← citeshttps://doi.org/10.1016/j.biopha.2020.110896openalex-snapshot

Over-expression of Kv4.3 gene reverses cardiac remodeling and transient-outward K+ current (Ito) reduction via CaMKII inhibition in myocardial infarction

inferred← citeshttps://doi.org/10.1016/j.bmcl.2017.10.040openalex-snapshot

Discovery of potent and selective inhibitors of calmodulin-dependent kinase II (CaMKII)

inferred← citeshttps://doi.org/10.1016/j.bpj.2010.08.016openalex-snapshot

Synergy between CaMKII Substrates and β-Adrenergic Signaling in Regulation of Cardiac Myocyte Ca2+ Handling

inferred← citeshttps://doi.org/10.1016/j.bpj.2011.11.3656openalex-snapshot

Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity Modulates Sinoatrial Nodal Pacemaker Cell Energetics

inferred← citeshttps://doi.org/10.1016/j.brainres.2021.147699openalex-snapshot

CaMKIIα knockout protects from ischemic neuronal cell death after resuscitation from cardiac arrest

inferred← citeshttps://doi.org/10.1016/j.cardiores.2005.08.011openalex-snapshot

Something old, something new: Changing views on the cellular mechanisms of heart failure

inferred← citeshttps://doi.org/10.1016/j.cardiores.2006.11.005openalex-snapshot

Role of Ca2+/calmodulin-dependent protein kinase (CaMK) in excitation–contraction coupling in the heart

inferred← citeshttps://doi.org/10.1016/j.cardiores.2006.12.009openalex-snapshot

Multiple downstream proarrhythmic targets for calmodulin kinase II: Moving beyond an ion channel-centric focus

inferred← citeshttps://doi.org/10.1016/j.cbpa.2022.102185openalex-snapshot

Perturbation of biological processes with small molecule kinase inhibitors

inferred← citeshttps://doi.org/10.1016/j.ceca.2010.02.001openalex-snapshot

Intracellular Ca2+ storage in health and disease: A dynamic equilibrium

inferred← citeshttps://doi.org/10.1016/j.ceca.2021.102483openalex-snapshot

Activation of transient receptor potential vanilloid 4 exacerbates myocardial ischemia-reperfusion injury via JNK-CaMKII phosphorylation pathway in isolated mice hearts

inferred← citeshttps://doi.org/10.1016/j.cell.2008.02.048openalex-snapshot

A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation

inferred← citeshttps://doi.org/10.1016/j.cell.2008.04.018openalex-snapshot

CaMKII: New Tricks for an Old Dog

inferred← citeshttps://doi.org/10.1016/j.cellsig.2021.110213openalex-snapshot

Protein phosphatase 2A in the healthy and failing heart: New insights and therapeutic opportunities

inferred← citeshttps://doi.org/10.1016/j.ddmec.2010.07.005openalex-snapshot

Ca2+/calmodulin-dependent protein kinase II in heart failure

inferred← citeshttps://doi.org/10.1016/j.ddstr.2005.08.011openalex-snapshot

Ryanodine receptors as drug targets for heart failure and cardiac arrhythmias

inferred← citeshttps://doi.org/10.1016/j.ejmech.2012.12.053openalex-snapshot

Characterization of a selective CaMKII peptide inhibitor

inferred← citeshttps://doi.org/10.1016/j.ejphar.2007.05.066openalex-snapshot

Calmodulin kinase II inhibition prevents arrhythmic activity induced by alpha and beta adrenergic agonists in rabbit pulmonary veins

inferred← citeshttps://doi.org/10.1016/j.ejphar.2023.175969openalex-snapshot

The novel peptide athycaltide-1 attenuates Ang II-induced pathological myocardial hypertrophy by reducing ROS and inhibiting the activation of CaMKII and ERK1/2

inferred← citeshttps://doi.org/10.1016/j.fsi.2021.12.054openalex-snapshot

The Eriocheir sinensis calcium/calmodulin-dependent protein kinase II activates apoptosis to resist Spiroplasma eriocheiris infection

inferred← citeshttps://doi.org/10.1016/j.hfc.2005.04.005openalex-snapshot

β-Adrenergic Receptors in Heart Failure

inferred← citeshttps://doi.org/10.1016/j.hrthm.2005.03.019openalex-snapshot

Calmodulin kinase II activity is required for normal atrioventricular nodal conduction

inferred← citeshttps://doi.org/10.1016/j.hrthm.2005.04.009openalex-snapshot

Is CaMKII a therapeutic target for ventricular rate control?

inferred← citeshttps://doi.org/10.1016/j.hrthm.2005.09.021openalex-snapshot

Neural modulation of cardiac arrhythmias and sudden cardiac death

inferred← citeshttps://doi.org/10.1016/j.hrthm.2010.07.029openalex-snapshot

Role of CaMKII in cardiovascular health, disease, and arrhythmia

inferred← citeshttps://doi.org/10.1016/j.hrthm.2010.10.001openalex-snapshot

Pinning down the CaMKII targets in the L-type Ca2+ channel: An essential step in defining CaMKII regulation

inferred← citeshttps://doi.org/10.1016/j.hrthm.2010.11.035openalex-snapshot

CaMKII regulation of phospholamban and SR Ca2+ load

inferred← citeshttps://doi.org/10.1016/j.hrthm.2011.04.027openalex-snapshot

Pathways for CaMKII activation in disease

inferred← citeshttps://doi.org/10.1016/j.hrthm.2012.08.026openalex-snapshot

CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome

inferred← citeshttps://doi.org/10.1016/j.hrthm.2012.12.016openalex-snapshot

Inhibition of CaMKII phosphorylation of RyR2 prevents inducible ventricular arrhythmias in mice with Duchenne muscular dystrophy

inferred← citeshttps://doi.org/10.1016/j.hrthm.2019.01.013openalex-snapshot

Calcium/calmodulin-dependent protein kinase II causes atrial structural remodeling associated with atrial fibrillation and heart failure

inferred← citeshttps://doi.org/10.1016/j.hrthm.2024.07.118openalex-snapshot

Ruxolitinib as a CaMKII inhibitor for treatment of cardiac arrhythmias: Applications and prospects

inferred← citeshttps://doi.org/10.1016/j.hrthm.2024.10.022openalex-snapshot

Calmodulin kinase II inhibition suppresses atrioventricular conduction by regulating intracellular Ca2+ homeostasis

inferred← citeshttps://doi.org/10.1016/j.ijcard.2013.03.069openalex-snapshot

Intravenous administration of Gr-1+CD11b+ myeloid cells increases neovascularization and improves cardiac function after heart infarction

inferred← citeshttps://doi.org/10.1016/j.ijcard.2014.11.159openalex-snapshot

Cardiac CaMKIIδ splice variants exhibit target signaling specificity and confer sex-selective arrhythmogenic actions in the ischemic-reperfused heart

inferred← citeshttps://doi.org/10.1016/j.ijcha.2019.100451openalex-snapshot

The progress and controversial of the use of beta blockers in patients with heart failure with a preserved ejection fraction

inferred← citeshttps://doi.org/10.1016/j.jacc.2014.11.028openalex-snapshot

Will Secretoneurin Be the Next Big Thing?

inferred← citeshttps://doi.org/10.1016/j.jacc.2018.01.060openalex-snapshot

Role of Stress Kinase JNK in Binge Alcohol-Evoked Atrial Arrhythmia

inferred← citeshttps://doi.org/10.1016/j.jare.2020.10.005openalex-snapshot

Calenduloside E suppresses calcium overload by promoting the interaction between L-type calcium channels and Bcl2-associated athanogene 3 to alleviate myocardial ischemia/reperfusion injury

inferred← citeshttps://doi.org/10.1016/j.jbc.2021.100893openalex-snapshot

Ca2+/calmodulin kinase II–dependent regulation of βIV-spectrin modulates cardiac fibroblast gene expression, proliferation, and contractility

inferred← citeshttps://doi.org/10.1016/j.jelectrocard.2007.05.022openalex-snapshot

Cellular basis for triggered ventricular arrhythmias that occur in the setting of compensated hypertrophy and heart failure: considerations for diagnosis and treatment

inferred← citeshttps://doi.org/10.1016/j.jep.2024.118143openalex-snapshot

Effect of traditional Chinese medicine on metabolism disturbance in ischemic heart diseases

inferred← citeshttps://doi.org/10.1016/j.jff.2018.02.030openalex-snapshot

Deciphering the multicomponent synergy mechanism from a systems pharmacology perspective: Application to Gualou Xiebai Decoction for coronary heart disease

inferred← citeshttps://doi.org/10.1016/j.jmb.2019.02.001openalex-snapshot

The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca2+/CaM

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2022.108990openalex-snapshot

Ellagic acid prevents myocardial infarction-induced left ventricular diastolic dysfunction in ovariectomized rats

inferred← citeshttps://doi.org/10.1016/j.joa.2014.04.003openalex-snapshot

Molecular mechanisms of heart failure progression associated with implantable cardioverter‐defibrillator shocks for ventricular tachyarrhythmias

inferred← citeshttps://doi.org/10.1016/j.jphs.2020.07.001openalex-snapshot

Sustained increased CaMKII phosphorylation is involved in the impaired regression of isoproterenol-induced cardiac hypertrophy in rats

inferred← citeshttps://doi.org/10.1016/j.lfs.2010.11.022openalex-snapshot

miRNAs got rhythm

inferred← citeshttps://doi.org/10.1016/j.lfs.2011.01.009openalex-snapshot

RETRACTED: Angiotensin receptor blockade improves the net balance of cardiac Ca2+ handling-related proteins in sympathetic hyperactivity-induced heart failure

inferred← citeshttps://doi.org/10.1016/j.lfs.2021.120220openalex-snapshot

NP202 treatment improves left ventricular systolic function and attenuates pathological remodelling following chronic myocardial infarction

inferred← citeshttps://doi.org/10.1016/j.lpm.2007.02.022openalex-snapshot

Approches physiopathologiques actuelles de l'insuffisance cardiaque

inferred← citeshttps://doi.org/10.1016/j.mad.2022.111758openalex-snapshot

Pathological implication of CaMKII in NF-κB pathway and SASP during cardiomyocytes senescence

inferred← citeshttps://doi.org/10.1016/j.molcel.2006.07.006openalex-snapshot

RETRACTED: L-Type Ca2+ Channel Facilitation Mediated by Phosphorylation of the β Subunit by CaMKII

inferred← citeshttps://doi.org/10.1016/j.mvr.2023.104565openalex-snapshot

Myocardial ischemia-reperfusion injury; Molecular mechanisms and prevention

inferred← citeshttps://doi.org/10.1016/j.nut.2013.05.006openalex-snapshot

Trigonelline isolated from fenugreek seed protects against isoproterenol-induced myocardial injury through down-regulation of Hsp27 and αB-crystallin

inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2008.02.003openalex-snapshot

Drugs that interact with cardiac electro-mechanics: Old and new targets for treatment

inferred← citeshttps://doi.org/10.1016/j.pharmthera.2005.04.006openalex-snapshot

Emerging concepts and therapeutic implications of β-adrenergic receptor subtype signaling

inferred← citeshttps://doi.org/10.1016/j.pharmthera.2010.04.005openalex-snapshot

Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies

inferred← citeshttps://doi.org/10.1016/j.pharmthera.2011.02.006openalex-snapshot

Two candidates at the heart of dysfunction: The ryanodine receptor and calcium/calmodulin protein kinase II as potential targets for therapeutic intervention—An in vivo perspective

inferred← citeshttps://doi.org/10.1016/j.phrs.2022.106119openalex-snapshot

Calcium dysregulation in heart diseases: Targeting calcium channels to achieve a correct calcium homeostasis

inferred← citeshttps://doi.org/10.1016/j.resuscitation.2009.06.003openalex-snapshot

Effect and mechanism of esmolol given during cardiopulmonary resuscitation in a porcine ventricular fibrillation model

inferred← citeshttps://doi.org/10.1016/j.semcdb.2006.11.012openalex-snapshot

Re-employment of developmental transcription factors in adult heart disease

inferred← citeshttps://doi.org/10.1016/j.taap.2012.10.013openalex-snapshot

Alpha B-crystallin prevents the arrhythmogenic effects of particulate matter isolated from ambient air by attenuating oxidative stress

inferred← citeshttps://doi.org/10.1016/j.tcm.2013.02.001openalex-snapshot

Compartmentalization of β-adrenergic signals in cardiomyocytes

inferred← citeshttps://doi.org/10.1016/j.tcm.2015.01.016openalex-snapshot

Calm down when the heart is stressed: Inhibiting calmodulin-dependent protein kinase II for antiarrhythmias

inferred← citeshttps://doi.org/10.1016/j.tem.2012.09.004openalex-snapshot

Aldosterone and cardiovascular disease: the heart of the matter

inferred← citeshttps://doi.org/10.1016/j.tips.2006.04.009openalex-snapshot

Subtype-specific α1- and β-adrenoceptor signaling in the heart

inferred← citeshttps://doi.org/10.1016/j.vph.2016.09.007openalex-snapshot

Role of CaMKII in Ang-II-dependent small artery remodeling

inferred← citeshttps://doi.org/10.1016/j.vph.2019.04.002openalex-snapshot

Compromised cardiovascular function in aged rats corresponds with increased expression and activity of calcium/calmodulin dependent protein kinase IIδ in aortic endothelium

inferred← citeshttps://doi.org/10.1016/j.ydbio.2009.03.024openalex-snapshot

Tbx5-mediated expression of Ca2+/calmodulin-dependent protein kinase II is necessary for zebrafish cardiac and pectoral fin morphogenesis

inferred← citeshttps://doi.org/10.1016/j.yexmp.2022.104815openalex-snapshot

Neurogranin regulates calcium-dependent cardiac hypertrophy

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2005.11.005openalex-snapshot

Suppression of dynamic Ca2+ transient responses to pacing in ventricular myocytes from mice with genetic calmodulin kinase II inhibition

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2006.08.115openalex-snapshot

Ryanodine receptors and ventricular arrhythmias: Emerging trends in mutations, mechanisms and therapies

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2006.09.005openalex-snapshot

Kinase inhibitors for cardiovascular disease

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2006.12.010openalex-snapshot

Reduced contractile response to α1-adrenergic stimulation in atria from mice with chronic cardiac calmodulin kinase II inhibition

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2007.05.004openalex-snapshot

Increased cardiomyocyte function and Ca2+ transients in mice during early congestive heart failure

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2007.09.008openalex-snapshot

Effects on recovery during acidosis in cardiac myocytes overexpressing CaMKII

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2007.10.014openalex-snapshot

Calmodulin kinase II inhibition disrupts cardiomyopathic effects of enhanced green fluorescent protein

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2008.05.011openalex-snapshot

Intracellular mechanisms of specific β-adrenoceptor antagonists involved in improved cardiac function and survival in a genetic model of heart failure

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2008.06.007openalex-snapshot

Role of activated CaMKII in abnormal calcium homeostasis and INa remodeling after myocardial infarction: Insights from mathematical modeling

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2008.09.002openalex-snapshot

With great power comes great responsibility: Using mouse genetics to study cardiac hypertrophy and failure

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2008.12.022openalex-snapshot

Local control of mitochondrial membrane potential, permeability transition pore and reactive oxygen species by calcium and calmodulin in rat ventricular myocytes

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2009.10.016openalex-snapshot

β-Adrenergic receptor signaling in the heart: Role of CaMKII

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2009.12.007openalex-snapshot

Ca2+/calmodulin-dependent protein kinase II contributes to intracellular pH recovery from acidosis via Na+/H+ exchanger activation

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2010.04.013openalex-snapshot

Na+/K+-ATPase inhibition by ouabain induces CaMKII-dependent apoptosis in adult rat cardiac myocytes

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2010.10.014openalex-snapshot

SR-targeted CaMKII inhibition improves SR Ca2+ handling, but accelerates cardiac remodeling in mice overexpressing CaMKIIδC

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2010.11.012openalex-snapshot

Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2010.12.002openalex-snapshot

Enhanced myofilament responsiveness upon β-adrenergic stimulation in post-infarct remodeled myocardium

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2011.01.012openalex-snapshot

CaMKII in myocardial hypertrophy and heart failure

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2011.07.016openalex-snapshot

CaMKII-dependent SR Ca leak contributes to doxorubicin-induced impaired Ca handling in isolated cardiac myocytes

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2011.08.010openalex-snapshot

Calcium-calmodulin dependent protein kinase II (CaMKII): A main signal responsible for early reperfusion arrhythmias

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2012.01.021openalex-snapshot

MyD88 mediated inflammatory signaling leads to CaMKII oxidation, cardiac hypertrophy and death after myocardial infarction

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2012.06.019openalex-snapshot

CaMKII effects on inotropic but not lusitropic force frequency responses require phospholamban

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2012.11.011openalex-snapshot

X-ROS signaling in the heart and skeletal muscle: Stretch-dependent local ROS regulates [Ca2+]i

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2013.02.014openalex-snapshot

While systolic cardiomyocyte function is preserved, diastolic myocyte function and recovery from acidosis are impaired in CaMKIIδ-KO mice

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2014.02.004openalex-snapshot

CaMKII oxidative activation and the pathogenesis of cardiac disease

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2014.03.001openalex-snapshot

Reactive oxygen species and excitation–contraction coupling in the context of cardiac pathology

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2015.06.007openalex-snapshot

CaMKIIδ mediates β-adrenergic effects on RyR2 phosphorylation and SR Ca2+ leak and the pathophysiological response to chronic β-adrenergic stimulation

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2015.10.014openalex-snapshot

Oxidant stress promotes disease by activating CaMKII

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2017.06.010openalex-snapshot

Role of CaMKII in free fatty acid/hyperlipidemia-induced cardiac remodeling both in vitro and in vivo

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2017.08.014openalex-snapshot

Nitric oxide and CaMKII: Critical steps in the cardiac contractile response To IGF-1 and swim training

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2018.03.020openalex-snapshot

The novel CaMKII inhibitor GS-680 reduces diastolic SR Ca leak and prevents CaMKII-dependent pro-arrhythmic activity

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2019.12.002openalex-snapshot

Ca2+/calmodulin-dependent protein kinase II is essential in hyperacute pressure overload

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2020.09.007openalex-snapshot

CaMKII exacerbates heart failure progression by activating class I HDACs

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2021.01.008openalex-snapshot

Computational modeling approaches to cAMP/PKA signaling in cardiomyocytes

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2023.10.003openalex-snapshot

CaMKII, ‘jack of all trades’ in inflammation during cardiac ischemia/reperfusion injury

inferred← citeshttps://doi.org/10.1016/s0167-7306(06)41012-7openalex-snapshot

Ryanodine receptor structure, function and pathophysiology

inferred← citeshttps://doi.org/10.1016/s1054-3589(10)59001-xopenalex-snapshot

The Ryanodine Receptor in Cardiac Physiology and Disease

inferred← citeshttps://doi.org/10.1016/s1063-5823(10)66005-xopenalex-snapshot

Regulation of Ryanodine Receptor Ion Channels Through Posttranslational Modifications

inferred← citeshttps://doi.org/10.1017/s0033583506004227openalex-snapshot

Computational biology in the study of cardiac ion channels and cell electrophysiology

inferred← citeshttps://doi.org/10.1021/pr1008702openalex-snapshot

Identification of CaMKII Phosphorylation Sites in Connexin43 by High-Resolution Mass Spectrometry

inferred← citeshttps://doi.org/10.1038/aps.2010.6openalex-snapshot

Protective action of tetramethylpyrazine phosphate against dilated cardiomyopathy in cTnTR141W transgenic mice

inferred← citeshttps://doi.org/10.1038/bjp.2008.127openalex-snapshot

Negative regulation of multifunctional Ca2+/calmodulin‐dependent protein kinases: physiological and pharmacological significance of protein phosphatases

inferred← citeshttps://doi.org/10.1038/emboj.2011.40openalex-snapshot

Conformational changes underlying calcium/calmodulin‐dependent protein kinase II activation

inferred← citeshttps://doi.org/10.1038/hr.2013.42openalex-snapshot

The main target for inhibiting mineralocorticoid receptor-mediated signaling in cardiovascular diseases

inferred← citeshttps://doi.org/10.1038/nature06798openalex-snapshot

Tackling heart failure in the twenty-first century

inferred← citeshttps://doi.org/10.1038/nature06799openalex-snapshot

A genetic framework for improving arrhythmia therapy

inferred← citeshttps://doi.org/10.1038/nature11444openalex-snapshot

CaMKII determines mitochondrial stress responses in heart

inferred← citeshttps://doi.org/10.1038/ncb0311-184openalex-snapshot

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

inferred← citeshttps://doi.org/10.1038/ncomms13189openalex-snapshot

CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation

inferred← citeshttps://doi.org/10.1038/ncpcardio0585openalex-snapshot

Disease mechanisms and emerging therapies: protein kinases and their inhibitors in myocardial disease

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