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A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1006/geno.1994.1016openalex-snapshot
Cloning of the cDNA Encoding Human Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) and Mapping of the TIMP3 Gene to Chromosome 22
inferredcites →https://doi.org/10.1006/mthe.2002.0606openalex-snapshot
Antitumor Activity and Bystander Effect of Adenovirally Delivered Tissue Inhibitor of Metalloproteinases-3
inferredcites →https://doi.org/10.1006/mvre.1994.1003openalex-snapshot
Quantitation of Angiogenesis and Antiangiogenesis in the Chick Embryo Chorioallantoic Membrane
inferredcites →https://doi.org/10.1007/bf02234786openalex-snapshot
Tissue inhibitor of metalloproteinase-3 is a basement membrane-associated protein that is significantly decreased in human colorectal cancer
inferredcites →https://doi.org/10.1007/bf03401579openalex-snapshot
The Tissue Inhibitor of Metalloproteinases-3 Gene in Breast Carcinoma: Identification of Multiple Polyadenylation Sites and a Stromal Pattern of Expression
inferredcites →https://doi.org/10.1007/pl00008707openalex-snapshot
A novel splice site mutation in the tissue inhibitor of the metalloproteinases-3 gene in Sorsby’s fundus dystrophy with unusual clinical features
inferredcites →https://doi.org/10.1016/0006-291x(92)90483-2openalex-snapshot
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
inferredcites →https://doi.org/10.1016/0076-6879(95)48032-3openalex-snapshot
[30] Tissue inhibitors of matrix metalloendopeptidases
inferredcites →https://doi.org/10.1016/0092-8674(93)90573-9openalex-snapshot
High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
inferredcites →https://doi.org/10.1016/s0002-9440(10)65138-3openalex-snapshot
Polarized Vascular Endothelial Growth Factor Secretion by Human Retinal Pigment Epithelium and Localization of Vascular Endothelial Growth Factor Receptors on the Inner Choriocapillaris
inferredcites →https://doi.org/10.1016/s0021-9258(18)41928-xopenalex-snapshot
A new inhibitor of metalloproteinases from chicken: ChIMP-3. A third member of the TIMP family.
inferredcites →https://doi.org/10.1016/s0021-9258(18)47116-5openalex-snapshot
Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.
inferredcites →https://doi.org/10.1016/s0021-9258(19)61475-4openalex-snapshot
A Novel Tissue Inhibitor of Metalloproteinases-3 Mutation Reveals a Common Molecular Phenotype in Sorsby's Fundus Dystrophy
inferredcites →https://doi.org/10.1016/s0092-8674(00)00139-2openalex-snapshot
MMP-9 Supplied by Bone Marrow–Derived Cells Contributes to Skin Carcinogenesis
inferredcites →https://doi.org/10.1016/s0092-8674(00)80283-4openalex-snapshot
A Requirement for Flk1 in Primitive and Definitive Hematopoiesis and Vasculogenesis
inferredcites →https://doi.org/10.1016/s0092-8674(00)81768-7openalex-snapshot
Matrix Metalloproteinases Regulate Neovascularization by Acting as Pericellular Fibrinolysins
inferredcites →https://doi.org/10.1016/s1055-3207(18)30071-1openalex-snapshot
The Role of Matrix Metalloproteinases in Tumor Invasion, Metastasis, and Angiogenesis
inferredcites →https://doi.org/10.1038/35036374openalex-snapshot
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
inferredcites →https://doi.org/10.1038/376062a0openalex-snapshot
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
inferredcites →https://doi.org/10.1038/376066a0openalex-snapshot
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
inferredcites →https://doi.org/10.1038/bjc.1997.285openalex-snapshot
TIMP-3 mRNA expression is regionally increased in moderately and poorly differentiated colorectal adenocarcinoma
inferredcites →https://doi.org/10.1038/ng1294-352openalex-snapshot
Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy
inferredcites →https://doi.org/10.1038/sj.bjc.6690217openalex-snapshot
Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3
inferredcites →https://doi.org/10.1042/bst025147sopenalex-snapshot
Matrix metalloproteinase and tissue inhibitor of metalloproteinase regulation of the invasive potential of a metastatic renal cell line
inferredcites →https://doi.org/10.1073/pnas.90.16.7533openalex-snapshot
Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium.
inferredcites →https://doi.org/10.1074/jbc.270.33.19312openalex-snapshot
Molecular Cloning of Mouse Tissue Inhibitor of Metalloproteinases-3 and Its Promoter
inferredcites →https://doi.org/10.1074/jbc.273.27.16778openalex-snapshot
Localization of the Functional Domains of Human Tissue Inhibitor of Metalloproteinases-3 and the Effects of a Sorsby's Fundus Dystrophy Mutation
inferredcites →https://doi.org/10.1074/jbc.m007929200openalex-snapshot
Localization of the Death Domain of Tissue Inhibitor of Metalloproteinase-3 to the N Terminus
inferredcites →https://doi.org/10.1074/jbc.m008157200openalex-snapshot
Tissue Inhibitor of Metalloproteinases-2 (TIMP-2) Suppresses TKR-Growth Factor Signaling Independent of Metalloproteinase Inhibition
inferredcites →https://doi.org/10.1074/jbc.m909677199openalex-snapshot
A Novel TIMP-3 Mutation Reveals a Common Molecular Phenotype in Sorsby's Fundus Dystrophy
inferredcites →https://doi.org/10.1093/carcin/17.9.1805openalex-snapshot
Suppression of in vivo tumor growth and induction of suspension cell death by tissue inhibitor of metalloproteinases (TIMP)-3
inferredcites →https://doi.org/10.1111/j.1699-0463.1999.tb01521.xopenalex-snapshot
Matrix‐degrading proteases and angiogenesis during development and tumor formation
inferredcites →https://doi.org/10.1126/science.1312256openalex-snapshot
The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor
inferredcites →https://doi.org/10.1136/bjo.82.11.1329openalex-snapshot
Accumulation of tissue inhibitor of metalloproteinases-3 in human eyes with Sorsby's fundus dystrophy or retinitis pigmentosa
inferredcites →https://doi.org/10.1139/o96-090openalex-snapshot
A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth
inferredcites →https://doi.org/10.1159/000468622openalex-snapshot
Angiogenesis: A Paradigm for Balanced Extracellular Proteolysis during Cell Migration and Morphogenesis
inferredcites →https://doi.org/10.1172/jci1584openalex-snapshot
Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis.
inferredcites →https://doi.org/10.1177/002215549804600403openalex-snapshot
Human TIMP-3 Is Expressed During Fetal Development, Hair Growth Cycle, and Cancer Progression
inferredcites →https://doi.org/10.1182/blood.v100.9.3361openalex-snapshot
Enforced expression of tissue inhibitor of matrix metalloproteinase-3 affects functional capillary morphogenesis and inhibits tumor growth in a murine tumor model
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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An Epigenetically Derived Monoclonal Origin for Recurrent Respiratory Papillomatosis
inferred← citeshttps://doi.org/10.1002/1873-3468.13556openalex-snapshot
Thermodynamic profiles of the interactions of suramin, chondroitin sulfate, and pentosan polysulfate with the inhibitory domain of TIMP ‐3
inferred← citeshttps://doi.org/10.1002/1878-0261.12796openalex-snapshot
CircFNDC3B sequestrates miR‐937‐5p to derepress TIMP3 and inhibit colorectal cancer progression
inferred← citeshttps://doi.org/10.1002/9780470015902.a0028558openalex-snapshot
Molecular Genetics of Sorsby Fundus Dystrophy
inferred← citeshttps://doi.org/10.1002/9780470669891.ch4openalex-snapshot
Matrix Metalloproteinases and their Inhibitors – Friend or Foe
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Metalloproteinases, the Endothelium, and Atherosclerosis
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Capillary Network‐Like Organization of Endothelial Cells in PEGDA Scaffolds Encoded with Angiogenic Signals via Triple Helical Hybridization
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Cartilage‐Mimicking Hybrid Avascular Hydrogel Scaffold for Stable Auricular Cartilage Regeneration in Microtia Reconstruction
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In Situ Deployment of Engineered Extracellular Vesicles into the Tumor Niche via Myeloid‐Derived Suppressor Cells
inferred← citeshttps://doi.org/10.1002/adma.200900608openalex-snapshot
In vivo Engineering of Tissues: Biological Considerations, Challenges, Strategies, and Future Directions
inferred← citeshttps://doi.org/10.1002/biof.1542openalex-snapshot
The role of epigenetic changes in preeclampsia
inferred← citeshttps://doi.org/10.1002/biof.2016openalex-snapshot
Pax‐8: Molecular biology, pathophysiology, and potential pathogenesis
inferred← citeshttps://doi.org/10.1002/bjs.6108openalex-snapshot
Antiangiogenic therapy and surgical practice
inferred← citeshttps://doi.org/10.1002/cncr.21657openalex-snapshot
CpG island hypermethylation in progression of esophageal and gastric cancer
inferred← citeshttps://doi.org/10.1002/ctm2.636openalex-snapshot
Novel insights into exosomal circular RNAs: Redefining intercellular communication in cancer biology
inferred← citeshttps://doi.org/10.1002/emmm.201201475openalex-snapshot
Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay
inferred← citeshttps://doi.org/10.1002/glia.20169openalex-snapshot
Multiple roles for MMPs and TIMPs in cerebral ischemia
inferred← citeshttps://doi.org/10.1002/ijc.20798openalex-snapshot
Identification and validation of novel ERBB2 (HER2, NEU) targets including genes involved in angiogenesis
inferred← citeshttps://doi.org/10.1002/ijc.20945openalex-snapshot
Metalloproteinases and their inhibitors in tumor angiogenesis
inferred← citeshttps://doi.org/10.1002/ijc.22110openalex-snapshot
Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer
inferred← citeshttps://doi.org/10.1002/ijc.24405openalex-snapshot
Polymorphisms in tissue inhibitors of metalloproteinases‐2 and ‐3 and breast cancer susceptibility and survival
inferred← citeshttps://doi.org/10.1002/ijc.24859openalex-snapshot
Stromal cell‐derived CSF‐1 blockade prolongs xenograft survival of CSF‐1‐negative neuroblastoma
inferred← citeshttps://doi.org/10.1002/ijc.24901openalex-snapshot
Snail is critical for tumor growth and metastasis of ovarian carcinoma
inferred← citeshttps://doi.org/10.1002/ijc.25404openalex-snapshot
TIMP‐3 promotes apoptosis in nonadherent small cell lung carcinoma cells lacking functional death receptor pathway
inferred← citeshttps://doi.org/10.1002/ijgo.14552openalex-snapshot
Circulating levels of tissue inhibitor of metalloproteinase 3, a protein with inhibitory effects on angiogenesis, are increased in pre‐eclampsia
inferred← citeshttps://doi.org/10.1002/jbmr.4396openalex-snapshot
Only the Co-Transcriptional Activity of β-Catenin Is Required for the Local Regulatory Effects in Hypertrophic Chondrocytes on Developmental Bone Modeling
inferred← citeshttps://doi.org/10.1002/jcb.21127openalex-snapshot
TIMP‐1 regulates cell proliferation by interacting with the ninth zinc finger domain of PLZF
inferred← citeshttps://doi.org/10.1002/jcp.20228openalex-snapshot
TGF‐β‐induced expression of tissue inhibitor of metalloproteinases‐3 gene in chondrocytes is mediated by extracellular signal‐regulated kinase pathway and Sp1 transcription factor
inferred← citeshttps://doi.org/10.1002/jcp.21526openalex-snapshot
Shear stress‐induced Ets‐1 modulates protease inhibitor expression in microvascular endothelial cells
inferred← citeshttps://doi.org/10.1002/jnr.10836openalex-snapshot
The TIMPs tango with MMPs and more in the central nervous system
inferred← citeshttps://doi.org/10.1002/jnr.24317openalex-snapshot
Sorsby fundus dystrophy:Insights from the past and looking to the future
inferred← citeshttps://doi.org/10.1002/jor.20219openalex-snapshot
Denervation alters mRNA levels of repair-associated genes in a rabbit medial collateral ligament injury model
inferred← citeshttps://doi.org/10.1002/jso.20663openalex-snapshot
Expression of tissue inhibitor of metalloproteinase‐3 (TIMP‐3) and its prognostic significance in resected non‐small cell lung cancer
inferred← citeshttps://doi.org/10.1002/jso.21462openalex-snapshot
Metalloproteinases and their regulators in colorectal cancer
inferred← citeshttps://doi.org/10.1002/path.1527openalex-snapshot
Vascular endothelial growth factor (VEGF) induces matrix metalloproteinase expression in immortalized chondrocytes
inferred← citeshttps://doi.org/10.1002/path.1528openalex-snapshot
Tissue inhibitors of metalloproteinase expression in human breast cancer: TIMP‐3 is associated with adjuvant endocrine therapy success
inferred← citeshttps://doi.org/10.1002/path.1548openalex-snapshot
TIMP‐3 and endocrine therapy of breast cancer: an apoptosis connection emerges
inferred← citeshttps://doi.org/10.1002/path.5506openalex-snapshot
In vitro stem cell modelling demonstrates a proof‐of‐concept for excess functional mutant TIMP3 as the cause of S orsby f undus d ystrophy
inferred← citeshttps://doi.org/10.1002/ptr.7942openalex-snapshot
Enterolactone and Trabectedin Suppress Epithelial Ovarian Cancer Synergistically Via Upregulating Thbs1
inferred← citeshttps://doi.org/10.1002/tsm2.280openalex-snapshot
Tendon blood flow, angiogenesis, and tendinopathy pathogenesis
inferred← citeshttps://doi.org/10.1007/0-387-22825-x_11openalex-snapshot
Turmoil in the Cardiac Myocyte: Acute Intracellular Activation of Matrix Metalloproteinases
inferred← citeshttps://doi.org/10.1007/3-540-26977-0_7openalex-snapshot
Experimental Models of Macular Degeneration
inferred← citeshttps://doi.org/10.1007/3-540-36028-x_6openalex-snapshot
Principles and Therapeutic Implications of Angiogenesis, Vasculogenesis and Arteriogenesis
inferred← citeshttps://doi.org/10.1007/3-7643-7311-3_18openalex-snapshot
Signal transduction in angiogenesis
inferred← citeshttps://doi.org/10.1007/978-0-387-69057-5_20openalex-snapshot
TIMPs: Extracellular Modifiers in Cancer Development
inferred← citeshttps://doi.org/10.1007/978-0-387-71518-6_5openalex-snapshot
Matrix Metalloproteinases and Their Endogenous Inhibitors
inferred← citeshttps://doi.org/10.1007/978-1-4419-1707-2_8openalex-snapshot
Well-Differentiated Papillary Thyroid Carcinoma
inferred← citeshttps://doi.org/10.1007/978-1-4419-7835-6_2openalex-snapshot
Molecular Control of Vascular Tube Morphogenesis and Stabilization: Regulation by Extracellular Matrix, Matrix Metalloproteinases, and Endothelial Cell–Pericyte Interactions
inferred← citeshttps://doi.org/10.1007/978-1-4614-0631-0_34openalex-snapshot
A Review and Update on the Molecular Basis of Pathogenesis of Sorsby Fundus Dystrophy
inferred← citeshttps://doi.org/10.1007/978-1-4614-5711-4_10openalex-snapshot
Cross-Talk Between MSCs and Their Environments
inferred← citeshttps://doi.org/10.1007/978-1-4614-5930-9_25openalex-snapshot
Tissue Inhibitor of Matrix Metalloproteinases in the Pathogenesis of Heart Failure Syndromes
inferred← citeshttps://doi.org/10.1007/978-1-4614-9099-9_16openalex-snapshot
Regulation of Proteolysis in Vascular Remodeling
inferred← citeshttps://doi.org/10.1007/978-1-59745-047-8_11openalex-snapshot
Vascular Endothelial Growth Factor and Retinal Diseases
inferred← citeshttps://doi.org/10.1007/978-1-59745-047-8_15openalex-snapshot
Regulation of Ocular Angiogenesis by Matrix Proteases and Tissue Inhibitors of Metalloproteinases
inferred← citeshttps://doi.org/10.1007/978-1-60327-299-5_2openalex-snapshot
Mouse Models of MMP and TIMP Function
inferred← citeshttps://doi.org/10.1007/978-1-61779-606-7_25openalex-snapshot
Dysfunction of Circulating Endothelial Progenitor Cells in Diabetic Retinopathy
inferred← citeshttps://doi.org/10.1007/978-2-8178-0466-8_8openalex-snapshot
Hypoxia and Extracellular Matrix Remodeling
inferred← citeshttps://doi.org/10.1007/978-3-030-59558-6_4openalex-snapshot
The Genomic Landscape of Meningiomas
inferred← citeshttps://doi.org/10.1007/978-3-031-19616-4_4openalex-snapshot
Collagens and Collagen-Degrading Enzymes in the Regulation of Angiogenesis
inferred← citeshttps://doi.org/10.1007/978-3-031-75937-6_6openalex-snapshot
Marker-Assisted Selection and Genetic Improvement of Industrial Crops
inferred← citeshttps://doi.org/10.1007/978-3-032-12705-1_8openalex-snapshot
Metabolic Mayhem in the Tumor Microenvironment: Can Mesenchymal Stromal Cells Restore Order?
inferred← citeshttps://doi.org/10.1007/978-3-319-33234-5_1openalex-snapshot
Tendonitis, Tendinosis, or Tendinopathy?
inferred← citeshttps://doi.org/10.1007/978-3-319-56133-2_1openalex-snapshot
Anatomy and Pathophysiology of Retinal Pigment Epithelial Detachment
inferred← citeshttps://doi.org/10.1007/978-3-319-57153-9_3openalex-snapshot
Stem Cell Therapy for Neurovascular and Traumatic Brain Diseases
inferred← citeshttps://doi.org/10.1007/978-3-319-57943-6_3openalex-snapshot
Peri-operative Shift in Angiogenesis-Related Factors in Breast Cancer Patients
inferred← citeshttps://doi.org/10.1007/978-3-319-76711-6_7openalex-snapshot
Mimetic Hierarchical Approaches for Osteochondral Tissue Engineering
inferred← citeshttps://doi.org/10.1007/978-3-319-99319-5_1openalex-snapshot
Molecular Control of Capillary Tube Morphogenesis and Maturation Through Endothelial Cell-Pericyte Interactions: Regulation by Small GTPase-Mediated Signaling, Kinase Cascades, Extracellular Matrix Remodeling, and Defined Growth Factors
inferred← citeshttps://doi.org/10.1007/978-3-540-29542-6_3openalex-snapshot
Retinal Angiogenesis and Growth Factors
inferred← citeshttps://doi.org/10.1007/978-3-642-16861-1_1openalex-snapshot
Matrix Metalloproteinases and Their Inhibitors in Turnover and Degradation of Extracellular Matrix
inferred← citeshttps://doi.org/10.1007/978-3-642-30856-7_9openalex-snapshot
ECM Remodeling in Angiogenesis
inferred← citeshttps://doi.org/10.1007/978-3-7643-8585-9_3openalex-snapshot
Role of matrix metalloproteases in pulmonary fibrosis
inferred← citeshttps://doi.org/10.1007/978-981-10-3162-5_3openalex-snapshot
Complex Mechanisms of Matrix Metalloproteinases Involvement in Endometrial Physiology and Pathology—An Update
inferred← citeshttps://doi.org/10.1007/978-981-10-6141-7_5openalex-snapshot
Endogenous Proteases in Tumoral Progression
inferred← citeshttps://doi.org/10.1007/978-981-16-7337-5_14openalex-snapshot
Other Macular Dystrophies 2
inferred← citeshttps://doi.org/10.1007/978-981-99-1529-3_3openalex-snapshot
MicroRNAs and Long Non-coding RNAs as Key Targets
inferred← citeshttps://doi.org/10.1007/s00018-005-4523-7openalex-snapshot
Biomedicine and diseases: the Klippel-Trenaunay syndrome, vascular anomalies and vascular morphogenesis
inferred← citeshttps://doi.org/10.1007/s00018-011-0763-xopenalex-snapshot
Matrix metalloproteinases in tumorigenesis: an evolving paradigm
inferred← citeshttps://doi.org/10.1007/s00018-013-1457-3openalex-snapshot
Cytokine functions of TIMP-1
inferred← citeshttps://doi.org/10.1007/s00018-021-04105-0openalex-snapshot
The essential anti-angiogenic strategies in cartilage engineering and osteoarthritic cartilage repair
inferred← citeshttps://doi.org/10.1007/s00125-007-0768-zopenalex-snapshot
Oxidised, glycated LDL selectively influences tissue inhibitor of metalloproteinase-3 gene expression and protein production in human retinal capillary pericytes
inferred← citeshttps://doi.org/10.1007/s00424-020-02432-yopenalex-snapshot
MiR-221-3p regulates the microvascular dysfunction in diabetic retinopathy by targeting TIMP3
inferred← citeshttps://doi.org/10.1007/s00432-010-0782-2openalex-snapshot
Expression of metalloproteases and their inhibitors by tumor and stromal cells in ductal carcinoma in situ of the breast and their relationship with microinvasive events
inferred← citeshttps://doi.org/10.1007/s00441-005-0123-yopenalex-snapshot
Differential regulation of TIMP-1, -2, and -3 mRNA and protein expressions during mouse incisor development
inferred← citeshttps://doi.org/10.1007/s00441-012-1410-zopenalex-snapshot
Matrix metalloproteinases and epidermal wound repair
inferred← citeshttps://doi.org/10.1007/s00508-025-02532-8openalex-snapshot
Markers for the angiogenic potential of fat grafts
inferred← citeshttps://doi.org/10.1007/s00592-013-0478-6openalex-snapshot
Expression of tissue inhibitor of metalloprotease 3 is reduced in ischemic but not neuropathic ulcers from patients with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.1007/s00705-013-1783-7openalex-snapshot
Matrix metalloproteinases and their tissue inhibitors in serum and cerebrospinal fluid of children with Japanese encephalitis virus infection
inferred← citeshttps://doi.org/10.1007/s10126-017-9757-5openalex-snapshot
Genome-Wide Association Study Reveals Multiple Novel QTL Associated with Low Oxygen Tolerance in Hybrid Catfish
inferred← citeshttps://doi.org/10.1007/s10142-024-01296-0openalex-snapshot
Identification of TIMPs signatures in Randall plaque from single-cell RNA sequencing (scRNA-Seq) analysis
inferred← citeshttps://doi.org/10.1007/s10456-007-9075-zopenalex-snapshot
Transcriptome analysis of endothelial cell gene expression induced by growth on matrigel matrices: identification and characterization of MAGP-2 and lumican as novel regulators of angiogenesis
inferred← citeshttps://doi.org/10.1007/s10456-013-9385-2openalex-snapshot
Differential TIMP3 expression affects tumor progression and angiogenesis in melanomas through regulation of directionally persistent endothelial cell migration
inferred← citeshttps://doi.org/10.1007/s10456-013-9389-yopenalex-snapshot
A peptide derived from TIMP-3 inhibits multiple angiogenic growth factor receptors and tumour growth and inflammatory arthritis in mice
inferred← citeshttps://doi.org/10.1007/s10456-017-9551-zopenalex-snapshot
Epigenetic approach for angiostatic therapy: promising combinations for cancer treatment
inferred← citeshttps://doi.org/10.1007/s10495-014-1076-yopenalex-snapshot
Tissue inhibitor of metalloproteinase-3 (TIMP3) promotes endothelial apoptosis via a caspase-independent mechanism
inferred← citeshttps://doi.org/10.1007/s10555-006-7893-xopenalex-snapshot
Novel functions of TIMPs in cell signaling
inferred← citeshttps://doi.org/10.1007/s10555-007-9105-8openalex-snapshot
The tumor microenvironment: regulation by MMP-independent effects of tissue inhibitor of metalloproteinases-2
inferred← citeshttps://doi.org/10.1007/s10555-010-9253-0openalex-snapshot
DNA methylation or histone modification status in metastasis and angiogenesis-related genes: a new hypothesis on usage of DNMT inhibitors and S-adenosylmethionine for genome stability
inferred← citeshttps://doi.org/10.1007/s10555-012-9387-3openalex-snapshot
EZH2 inhibition: targeting the crossroad of tumor invasion and angiogenesis
inferred← citeshttps://doi.org/10.1007/s10555-019-09812-6openalex-snapshot
Functional disparities within the TIMP family in cancer: hints from molecular divergence
inferred← citeshttps://doi.org/10.1007/s10585-019-10017-yopenalex-snapshot
Tissue inhibitor of matrix metalloproteinase-3 has both anti-metastatic and anti-tumourigenic properties
inferred← citeshttps://doi.org/10.1007/s10741-011-9266-yopenalex-snapshot
Tissue inhibitor of metalloproteinases (TIMPs) in heart failure
inferred← citeshttps://doi.org/10.1007/s10815-015-0529-8openalex-snapshot
Contribution of TIMP3 polymorphisms to the development of preeclampsia in Han Chinese women
inferred← citeshttps://doi.org/10.1007/s11033-022-07559-yopenalex-snapshot
The novel histone deacetylase inhibitor pracinostat suppresses the malignant phenotype in human glioma
inferred← citeshttps://doi.org/10.1007/s11033-025-10250-7openalex-snapshot
Aberrant DNA methylation of EDNRB, MGMT and TIMP3 gene promoters in saliva of head and neck carcinoma patients as a diagnostic tool
inferred← citeshttps://doi.org/10.1007/s11033-025-10721-xopenalex-snapshot
Epigenetic silencing of the tumor suppressor TIMP-3 gene in upstream CpG islands in thyroid neoplasms: a cross-sectional study with systematic review
inferred← citeshttps://doi.org/10.1007/s11060-006-9309-8openalex-snapshot
Frequent but borderline methylation of p16 INK4a and TIMP3 in medulloblastoma and sPNET revealed by quantitative analyses
inferred← citeshttps://doi.org/10.1007/s11239-020-02329-8openalex-snapshot
Extracellular matrix collagen biomarkers levels in patients with chronic thromboembolic pulmonary hypertension
inferred← citeshttps://doi.org/10.1007/s12031-015-0698-zopenalex-snapshot
The Clinical Utility of TIMP3 Expression in ACTH-Secreting Pituitary Tumor
inferred← citeshttps://doi.org/10.1007/s12094-022-02829-4openalex-snapshot
CircRNAs: promising factors for regulating angiogenesis in colorectal cancer
inferred← citeshttps://doi.org/10.1007/s12156-010-0035-2openalex-snapshot
From the endometrium physiology to a comprehensive strategy for the discovery of ovarian cancer biomarkers
inferred← citeshttps://doi.org/10.1007/s13277-014-2955-0openalex-snapshot
Knockdown of the AKT3 (PKBγ), PI3KCA, and VEGFR2 genes by RNA interference suppresses glioblastoma multiforme T98G cells invasiveness in vitro
inferred← citeshttps://doi.org/10.1007/s13277-014-3017-3openalex-snapshot
MiR-221/222 promote human glioma cell invasion and angiogenesis by targeting TIMP2
inferred← citeshttps://doi.org/10.1007/s40291-016-0186-3openalex-snapshot
miR-21 Might be Involved in Breast Cancer Promotion and Invasion Rather than in Initial Events of Breast Cancer Development
inferred← citeshttps://doi.org/10.1007/s40291-016-0230-3openalex-snapshot
Changes in miR-221/222 Levels in Invasive and In Situ Carcinomas of the Breast: Differences in Association with Estrogen Receptor and TIMP3 Expression Levels
inferred← citeshttps://doi.org/10.1016/b978-0-12-375709-8.00032-0openalex-snapshot
Cancer Epigenetics
inferred← citeshttps://doi.org/10.1016/b978-0-12-386041-5.00003-0openalex-snapshot
Molecular Basis for Endothelial Lumen Formation and Tubulogenesis During Vasculogenesis and Angiogenic Sprouting
inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.99828-3openalex-snapshot
OBSOLETE: Cardiac Fibroblast
inferred← citeshttps://doi.org/10.1016/b978-0-12-802385-3.00006-1openalex-snapshot
Vasculogenesis and Angiogenesis
inferred← citeshttps://doi.org/10.1016/b978-0-12-802734-9.00032-9openalex-snapshot
Engineering Vascular Niche for Bone Tissue Regeneration
inferred← citeshttps://doi.org/10.1016/b978-0-12-803239-8.00026-0openalex-snapshot
Epigenetic Control in Human Normal Follicular Thyroid Cells and in Thyroid Carcinoma
inferred← citeshttps://doi.org/10.1016/b978-0-12-809657-4.99828-4openalex-snapshot
Cardiac Fibroblast
inferred← citeshttps://doi.org/10.1016/b978-0-323-04332-8.00084-6openalex-snapshot
Macular Dystrophies
inferred← citeshttps://doi.org/10.1016/b978-0-443-30098-1.00004-5openalex-snapshot
Matrix metalloproteinases and uveal melanoma
inferred← citeshttps://doi.org/10.1016/b978-1-4557-0737-9.00020-5openalex-snapshot
Structure, Function, and Pathology of Bruch's Membrane
inferred← citeshttps://doi.org/10.1016/b978-1-4557-0737-9.00042-4openalex-snapshot
Macular Dystrophies
inferred← citeshttps://doi.org/10.1016/bs.enz.2026.05.001openalex-snapshot
Tissue inhibitors of metalloproteinases (TIMPs)
inferred← citeshttps://doi.org/10.1016/bs.ircmb.2023.04.002openalex-snapshot
Novel insights into DNA methylation-based epigenetic regulation of breast tumor angiogenesis
inferred← citeshttps://doi.org/10.1016/bs.pmbts.2017.01.001openalex-snapshot
The Balance Between Metalloproteinases and TIMPs
inferred← citeshttps://doi.org/10.1016/bs.pmbts.2017.05.001openalex-snapshot
Matrix Metalloproteinases in Bone Resorption, Remodeling, and Repair
inferred← citeshttps://doi.org/10.1016/j.aanat.2005.06.008openalex-snapshot
The influence of biomechanical parameters on the expression of VEGF and endostatin in the bone and joint system
inferred← citeshttps://doi.org/10.1016/j.actbio.2016.08.030openalex-snapshot
Structural and functional insights into the interaction of sulfated glycosaminoglycans with tissue inhibitor of metalloproteinase-3 – A possible regulatory role on extracellular matrix homeostasis
inferred← citeshttps://doi.org/10.1016/j.actbio.2018.03.012openalex-snapshot
3D-printed IFN-γ-loading calcium silicate-β-tricalcium phosphate scaffold sequentially activates M1 and M2 polarization of macrophages to promote vascularization of tissue engineering bone
inferred← citeshttps://doi.org/10.1016/j.actbio.2022.08.060openalex-snapshot
Matrix produced by diseased cardiac fibroblasts affects early myotube formation and function
inferred← citeshttps://doi.org/10.1016/j.addr.2016.11.003openalex-snapshot
Gene delivery nanoparticles to modulate angiogenesis
inferred← citeshttps://doi.org/10.1016/j.ajo.2006.06.003openalex-snapshot
A Novel His158Arg Mutation in TIMP3 Causes a Late-Onset Form of Sorsby Fundus Dystrophy
inferred← citeshttps://doi.org/10.1016/j.ajo.2008.03.024openalex-snapshot
Clinical Course and Treatment Outcomes of Sorsby Fundus Dystrophy
inferred← citeshttps://doi.org/10.1016/j.ajpath.2011.07.035openalex-snapshot
Endogenous Angiogenesis Inhibitor Blocks Tumor Growth via Direct and Indirect Effects on Tumor Microenvironment
inferred← citeshttps://doi.org/10.1016/j.ajpath.2011.09.008openalex-snapshot
An Alternate Perspective on the Roles of TIMPs and MMPs in Pathology
inferred← citeshttps://doi.org/10.1016/j.ajpath.2013.05.010openalex-snapshot
Integrin α7 Binds Tissue Inhibitor of Metalloproteinase 3 to Suppress Growth of Prostate Cancer Cells
inferred← citeshttps://doi.org/10.1016/j.amjsurg.2003.07.023openalex-snapshot
Altered expression of vascular endothelial growth factor and its receptors in normal saphenous vein and in arterialized and stenotic vein grafts
inferred← citeshttps://doi.org/10.1016/j.apmt.2021.101213openalex-snapshot
Dynamic flow enables long‐term maintenance of 3‐D vascularized human skin models
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2013.01.024openalex-snapshot
The role of ADAM17 in metabolic inflammation
inferred← citeshttps://doi.org/10.1016/j.bbadis.2016.07.011openalex-snapshot
Chronic venous disease – Part II: Proteolytic biomarkers in wound healing
inferred← citeshttps://doi.org/10.1016/j.bbadis.2024.167087openalex-snapshot
TIMP3/Wnt axis regulates gliosis of Müller glia
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2010.01.003openalex-snapshot
The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity
inferred← citeshttps://doi.org/10.1016/j.bbcan.2005.03.001openalex-snapshot
Gelatinase-mediated migration and invasion of cancer cells
inferred← citeshttps://doi.org/10.1016/j.bbcan.2006.07.003openalex-snapshot
Dual targeting of epigenetic therapy in cancer
inferred← citeshttps://doi.org/10.1016/j.bbi.2023.08.005openalex-snapshot
Single-cell analysis of dorsal root ganglia reveals metalloproteinase signaling in satellite glial cells and pain
inferred← citeshttps://doi.org/10.1016/j.bbrc.2004.08.219openalex-snapshot
Insulin-like growth factor-1 contributes to neovascularization in age-related macular degeneration
inferred← citeshttps://doi.org/10.1016/j.bbrc.2004.09.011openalex-snapshot
Effects of IL-1β on gene expression in human rheumatoid synovial fibroblasts
inferred← citeshttps://doi.org/10.1016/j.bbrc.2005.11.146openalex-snapshot
Immune suppressor factor confers stromal cell line with enhanced supporting activity for hematopoietic stem cells
inferred← citeshttps://doi.org/10.1016/j.bbrc.2006.04.083openalex-snapshot
Modulation of angiogenesis by tissue inhibitor of metalloproteinase-4
inferred← citeshttps://doi.org/10.1016/j.bbrc.2006.05.044openalex-snapshot
TIMP-2 promotes cell spreading and adhesion via upregulation of Rap1 signaling
inferred← citeshttps://doi.org/10.1016/j.bbrc.2007.02.038openalex-snapshot
Augmentation of vascular permeability of VEGF is enhanced by KDR-binding proteins
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2026.02.010openalex-snapshot
Glycosaminoglycan-functionalized hydrogels for sustained delivery of tissue inhibitor of metalloproteinase-3 mediating matrix metalloprotease inhibition and extracellular matrix stabilization
inferred← citeshttps://doi.org/10.1016/j.biocel.2007.10.024openalex-snapshot
Metalloproteinases and their inhibitors: Regulators of wound healing
inferred← citeshttps://doi.org/10.1016/j.biocel.2011.08.012openalex-snapshot
Targeting angiogenesis with compounds from the extracellular matrix
inferred← citeshttps://doi.org/10.1016/j.biochi.2004.07.012openalex-snapshot
Membrane type-matrix metalloproteinases and tumor progression
inferred← citeshttps://doi.org/10.1016/j.biochi.2004.09.022openalex-snapshot
Beneficial and detrimental influences of tissue inhibitor of metalloproteinase-1 (TIMP-1) in tumor progression
inferred← citeshttps://doi.org/10.1016/j.biomag.2013.06.003openalex-snapshot
Metalloproteinases and eye diseases
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2011.10.042openalex-snapshot
Glycosaminoglycan (GAG) binding surfaces for characterizing GAG-protein interactions
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2014.02.012openalex-snapshot
The role of macrophage phenotype in vascularization of tissue engineering scaffolds
inferred← citeshttps://doi.org/10.1016/j.biopha.2021.111681openalex-snapshot
Anti-neoplastic and demethylating activity of a newly synthetized flavanone-derived compound in Renal Cell Carcinoma cell lines
inferred← citeshttps://doi.org/10.1016/j.bonr.2020.100715openalex-snapshot
Concerted actions by MMPs, ADAMTS and serine proteases during remodeling of the cartilage callus into bone during osseointegration of hip implants
inferred← citeshttps://doi.org/10.1016/j.cancergen.2019.08.006openalex-snapshot
Potential of epigenetic events in human thyroid cancer
inferred← citeshttps://doi.org/10.1016/j.canlet.2010.01.021openalex-snapshot
Inhibition of angiogenesis by the BTB domain of promyelocytic leukemia zinc finger protein
inferred← citeshttps://doi.org/10.1016/j.canlet.2013.10.037openalex-snapshot
TIMP-2-derived 18-mer peptide inhibits endothelial cell proliferation and migration through cAMP/PKA-dependent mechanism
inferred← citeshttps://doi.org/10.1016/j.canlet.2015.09.021openalex-snapshot
Marmesin is a novel angiogenesis inhibitor: Regulatory effect and molecular mechanism on endothelial cell fate and angiogenesis
inferred← citeshttps://doi.org/10.1016/j.carbpol.2020.117308openalex-snapshot
The anti-cancer effects and mechanisms of lactic acid bacteria exopolysaccharides in vitro: A review
inferred← citeshttps://doi.org/10.1016/j.cardiores.2007.05.006openalex-snapshot
Endothelial nitric oxide synthase promotes neonatal cardiomyocyte proliferation by inhibiting tissue inhibitor of metalloproteinase-3 expression
inferred← citeshttps://doi.org/10.1016/j.cej.2026.172567openalex-snapshot
Phthalocyanine-based prodrug with H₂S-triggered domino cascade for photodynamic and multiple-mechanism synergistic anti-metastatic therapy
inferred← citeshttps://doi.org/10.1016/j.cell.2017.06.035openalex-snapshot
Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis
inferred← citeshttps://doi.org/10.1016/j.clbc.2016.05.007openalex-snapshot
Expression and Clinical Significance of Metalloproteases and Their Inhibitors by Endothelial Cells From Invasive Breast Carcinomas
inferred← citeshttps://doi.org/10.1016/j.ddmod.2011.03.004openalex-snapshot
Angiogenesis and proteinases: influence on vascular morphogenesis, stabilization and regression
inferred← citeshttps://doi.org/10.1016/j.devcel.2009.01.013openalex-snapshot
Cellular and Molecular Mechanisms of Vascular Lumen Formation
inferred← citeshttps://doi.org/10.1016/j.devcel.2018.01.018openalex-snapshot
Pericyte ALK5/TIMP3 Axis Contributes to Endothelial Morphogenesis in the Developing Brain
inferred← citeshttps://doi.org/10.1016/j.ebiom.2021.103634openalex-snapshot
Primary head and neck tumour-derived fibroblasts promote lymphangiogenesis in a lymphatic organotypic co-culture model
inferred← citeshttps://doi.org/10.1016/j.ejca.2010.01.009openalex-snapshot
Loss of expression of TIMP3 in clear cell renal cell carcinoma
inferred← citeshttps://doi.org/10.1016/j.ejca.2015.09.014openalex-snapshot
Association of TIMP3 expression with vessel density, macrophage infiltration and prognosis in human malignant melanoma
inferred← citeshttps://doi.org/10.1016/j.ejca.2016.06.020openalex-snapshot
Tissue inhibitor of metalloproteinase-3 (TIMP3) expression decreases during melanoma progression and inhibits melanoma cell migration
inferred← citeshttps://doi.org/10.1016/j.ejphar.2020.173591openalex-snapshot
The anti-inflammatory protein MCPIP1 inhibits the development of ccRCC by maintaining high levels of tumour suppressors
inferred← citeshttps://doi.org/10.1016/j.envres.2024.120214openalex-snapshot
Alterations in the placental proteome in association with the presence of black carbon particles: A discovery study
inferred← citeshttps://doi.org/10.1016/j.exer.2010.05.012openalex-snapshot
Impaired function of circulating CD34+ CD45− cells in patients with proliferative diabetic retinopathy
inferred← citeshttps://doi.org/10.1016/j.exer.2017.08.014openalex-snapshot
Sorsby fundus dystrophy – A review of pathology and disease mechanisms
inferred← citeshttps://doi.org/10.1016/j.exer.2017.11.006openalex-snapshot
miR-365 promotes diabetic retinopathy through inhibiting Timp3 and increasing oxidative stress
inferred← citeshttps://doi.org/10.1016/j.exer.2020.108363openalex-snapshot
Corneal neovascularization
inferred← citeshttps://doi.org/10.1016/j.exphem.2013.04.010openalex-snapshot
The tissue inhibitor of metalloproteinases-1 improves migration and adhesion of hematopoietic stem and progenitor cells
inferred← citeshttps://doi.org/10.1016/j.expneurol.2026.115935openalex-snapshot
Mesenchymal stem cell-derived secretome in traumatic brain injury: Stage-specific paracrine mechanisms and translational challenges
inferred← citeshttps://doi.org/10.1016/j.fas.2014.02.010openalex-snapshot
The pathogenesis of Achilles tendinopathy: A systematic review
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2013.02.018openalex-snapshot
Genetic variation in tissue inhibitors of metalloproteinases as a risk factor for idiopathic recurrent spontaneous abortion
inferred← citeshttps://doi.org/10.1016/j.fmre.2023.12.015openalex-snapshot
Macrophage regulation in vascularization upon regeneration and repair of tissue injury and engineered organ transplantation
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2005.03.033openalex-snapshot
Matrix metalloproteinases and free radicals in cerebral ischemia
inferred← citeshttps://doi.org/10.1016/j.gene.2013.06.087openalex-snapshot
Impact of MMP-3 and TIMP-3 gene polymorphisms on prostate cancer susceptibility in North Indian cohort
inferred← citeshttps://doi.org/10.1016/j.gene.2020.144700openalex-snapshot
Associations of IL6 rs1800795, BLK rs13277113, TIMP3 rs9621532, IL1RL1 rs1041973 and IL1RAP rs4624606 single gene polymorphisms with laryngeal squamous cell carcinoma
inferred← citeshttps://doi.org/10.1016/j.ijcard.2015.01.091openalex-snapshot
Cardiac tissue inhibitor of matrix metalloprotease 4 dictates cardiomyocyte contractility and differentiation of embryonic stem cells into cardiomyocytes: Road to therapy
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