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Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/bf00437479openalex-snapshot
A systems approach to cancer therapy
inferredcites →https://doi.org/10.1016/s0140-6736(03)13603-3openalex-snapshot
Antiangiogenesis drug promising for metastatic colorectal cancer
inferredcites →https://doi.org/10.1038/35025220openalex-snapshot
Angiogenesis in cancer and other diseases
inferredcites →https://doi.org/10.1038/nm0603-669openalex-snapshot
The biology of VEGF and its receptors
inferredcites →https://doi.org/10.1038/nm0603-685openalex-snapshot
Molecular regulation of vessel maturation
inferredcites →https://doi.org/10.1038/nm0901-987openalex-snapshot
Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
inferredcites →https://doi.org/10.1038/nrc905openalex-snapshot
Clinical translation of angiogenesis inhibitors
inferredcites →https://doi.org/10.1038/nrc925openalex-snapshot
Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy?
inferredcites →https://doi.org/10.1038/sj.bjc.6601005openalex-snapshot
Effect of antivascular endothelial growth factor treatment on the intratumoral uptake of CPT-11
inferredcites →https://doi.org/10.1056/nejmoa021491openalex-snapshot
A Randomized Trial of Bevacizumab, an Anti–Vascular Endothelial Growth Factor Antibody, for Metastatic Renal Cancer
inferredcites →https://doi.org/10.1073/pnas.93.25.14765openalex-snapshot
Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody
inferredcites →https://doi.org/10.1182/blood.v97.11.3658openalex-snapshot
Resting and activated endothelial cells are increased in the peripheral blood of cancer patients
inferredcites →https://doi.org/10.1200/jco.2002.10.088openalex-snapshot
Vascular Permeability Factor/Vascular Endothelial Growth Factor: A Critical Cytokine in Tumor Angiogenesis and a Potential Target for Diagnosis and Therapy
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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The VEGF and HER2 Expressions as Prognostic Factors in Osteosarcoma Patients
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Phase 2 study of carboplatin, irinotecan, and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy
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Phase 2 trial of concurrent bevacizumab and transhepatic arterial chemoembolization in patients with unresectable hepatocellular carcinoma
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Phase 2 study of S‐1 and carboplatin plus bevacizumab followed by maintenance S‐1 and bevacizumab for chemotherapy‐naive patients with advanced nonsquamous non–small cell lung cancer
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NRG Oncology / RTOG 0921: A phase 2 study of postoperative intensity‐modulated radiotherapy with concurrent cisplatin and bevacizumab followed by carboplatin and paclitaxel for patients with endometrial cancer
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Development of antibody-based therapeutics for oncology indications
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Phase II study of bevacizumab in combination with docetaxel and radiation in locally advanced squamous cell carcinoma of the head and neck
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Adeno-associated virus-mediated expression of apolipoprotein (a) kringles suppresses hepatocellular carcinoma growth in mice
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Antihepatoma activity of chaetocin due to deregulated splicing of hypoxia-inducible factor 1α pre-mRNA in mice and in vitro
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Vascular density in colorectal liver metastases increases after removal of the primary tumor in human cancer patients
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Anginex synergizes with radiation therapy to inhibit tumor growth by radiosensitizing endothelial cells
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Metalloproteinases and their inhibitors in tumor angiogenesis
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Molecular determinants of response to RTK‐targeting agents in nonsmall cell lung cancer
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Outgrowth of human liver metastases after resection of the primary colorectal tumor: A shift in the balance between apoptosis and proliferation
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Inhibition of carcinoma cell‐derived VEGF reduces inflammatory characteristics in xenograft carcinoma
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Experimental anti‐angiogenesis causes upregulation of genes associated with poor survival in glioblastoma
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Combined targeting of interleukin‐6 and vascular endothelial growth factor potently inhibits glioma growth and invasiveness
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Emergence of potential biomarkers of response to anti‐angiogenic anti‐tumour agents
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Influence of soluble or matrix-bound isoforms of vascular endothelial growth factor-A on tumor response to vascular-targeted strategies
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Microvessel density and endothelial cell proliferation levels in colorectal liver metastases from patients given neo‐adjuvant cytotoxic chemotherapy and bevacizumab
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Gr-1+CD11b+ myeloid-derived suppressor cells: Formidable partners in tumor metastasis
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Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize
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Tumor Vasculature Is Regulated by FGF/FGFR Signaling‐Mediated Angiogenesis and Bone Marrow‐Derived Cell Recruitment: This Mechanism Is Inhibited by SSR128129E, the First Allosteric Antagonist of FGFRs
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Roles of apelin/APJ system in cancer: Biomarker, predictor, and emerging therapeutic target
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ベバシズマブを含む化学療法中の直腸癌患者に発症したA群β溶連菌による壊死性筋膜炎の1例(A case of group A beta streptococcal necrotizing fasciitis in a patient with rectal cancer underwent chemotherapy including bevacizumab)
inferred← citeshttps://doi.org/10.1002/jso.20254openalex-snapshot
Apoptotic and anti-angiogenic strategies in liver and gastrointestinal malignancies
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Radiation and chemoradiation therapy for esophageal adenocarcinoma
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Re: The risk of developing metastatic disease in colorectal cancer is related to CD105-positive vessel count, by Romani AA, Borghetti AF, Del Rio P, et al.
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Antiangiogenic antibody improves melanoma detection by fluorescently labeled therapeutic antibodies
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Effects of radiation on tumor vasculature
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Targeting Tumor Stroma: Current Challenges and Future Directions
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Angiogenesis as a strategic target for prostate cancer therapy
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Comparison of quantitative parameters in cervix cancer measured by dynamic contrast–enhanced MRI and CT
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Noncompartmental kinetic analysis of DCE‐MRI data from malignant tumors: Application to glioblastoma treated with bevacizumab
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Multimodality treatment of osteosarcoma: Radiation in a high‐risk cohort
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Modeling and predicting optimal treatment scheduling between the antiangiogenic drug sunitinib and irinotecan in preclinical settings
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Modulation of Tumor Vasculature Network: Key Strategies
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Application of nanotechnology for enhancing photodynamic therapy via ameliorating, neglecting, or exploiting tumor hypoxia
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Role of fibroblast growth factor signaling in vascular formation and maintenance: orchestrating signaling networks as an integrated system
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Minimally Invasive Biomarkers for Therapy Monitoring
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Neue Therapiekonzepte mit molekularen Strategien
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Integration of Biological Therapies in Locally Advanced Non-Small-Cell Lung Cancer
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Applications in Rectal and Anal Cancer
inferred← citeshttps://doi.org/10.1007/3-540-35662-2_20openalex-snapshot
Applications to Gynecological Cancers
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Clinical Principles and Applications of Chemoirradiation
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Mechanobiological Modelling of Angiogenesis: Impact on Tissue Engineering and Bone Regeneration
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Chemotherapy in Rectal Cancer
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Advancement of Antiangiogenic and Vascular Disrupting Agents Combined with Radiation
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Preclinical Models of Regional Lymph Node Tumor Metastasis
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Novel Approaches in Chemoradiation for Localized Pancreas Cancer
inferred← citeshttps://doi.org/10.1007/978-0-387-71518-6_21openalex-snapshot
Contribution of Endothelial Progenitor Cells to the Angiogenic Process
inferred← citeshttps://doi.org/10.1007/978-0-387-71518-6_24openalex-snapshot
Normalization of Tumor Vasculature and Microenvironment
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Surrogates for Clinical Development
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Combination of Antiangiogenic Therapy with Other Anticancer Therapies
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Immunotherapy of Angiogenesis with DNA Vaccines
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Challenges of Antiangiogenic Therapy of Tumors
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Monoclonal Antibodies as Therapeutic Agents
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Vascular Endothelial Growth Factor Inhibitors in Colon Cancer
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Quantitative Assessment of Colorectal Cancer Perfusion: Perfusion Computed Tomography and Dynamic Contrast Enhanced Magnetic Resonance Imaging
inferred← citeshttps://doi.org/10.1007/978-1-4020-9545-0_22openalex-snapshot
Chemoradiation for Rectal Cancer
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Pharmaceutical Perspectives of Cancer Therapeutics: Current Therapeutic Uses of Monoclonal Antibodies
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Non-Surgical Treatment of Pulmonary and Extra-pulmonary Metastases
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Antiangiogenic Strategies for the Treatment of Gliomas
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Memory T-Cell Responses and Survival in Human Cancer: Remember to Stay Alive
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Contrast Ultrasound in Imaging Tumor Angiogenesis
inferred← citeshttps://doi.org/10.1007/978-1-4419-6744-2_10openalex-snapshot
Clinical Advances by the MGH Department of Radiation Oncology
inferred← citeshttps://doi.org/10.1007/978-1-4419-6744-2_8openalex-snapshot
Radiation Biology of Tumor and Normal Tissues
inferred← citeshttps://doi.org/10.1007/978-1-4419-7358-0_11openalex-snapshot
Imaging Studies in Anticancer Drug Development
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Targeted Therapeutics in Cancer Treatment
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Pharmacodynamic Studies in Early Phase Drug Development
inferred← citeshttps://doi.org/10.1007/978-1-4614-0052-3_14openalex-snapshot
Blood Perfusion in Solid Tumor with “Normalized” Microvasculature
inferred← citeshttps://doi.org/10.1007/978-1-4614-0052-3_9openalex-snapshot
Modeling Structural and Functional Adaptation of Tumor Vessel Networks During Antiangiogenic Therapy
inferred← citeshttps://doi.org/10.1007/978-1-4614-1445-2_3openalex-snapshot
Insights into the Regulation of Tumor Dormancy by Angiogenesis in Experimental Tumors
inferred← citeshttps://doi.org/10.1007/978-1-4614-3235-7_7openalex-snapshot
Lymph and Lymphatic Capillaries in Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4614-4178-6_5openalex-snapshot
Modeling Tumor Blood Vessel Dynamics
inferred← citeshttps://doi.org/10.1007/978-1-4614-6176-0_4openalex-snapshot
Impact of Genetic Targets on Cancer Therapy: Hepatocellular Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4614-7876-8_9openalex-snapshot
Pressure Gradients in Solid Tumors
inferred← citeshttps://doi.org/10.1007/978-1-4939-1176-9_15openalex-snapshot
Angiogenesis Inhibition in Castration-Resistant Prostate Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4939-1622-1_11openalex-snapshot
Anti-VEGF and VEGFR Monoclonal Antibodies in RCC
inferred← citeshttps://doi.org/10.1007/978-1-4939-2047-1_14openalex-snapshot
Targeted Therapy in Gastrointestinal Stromal Tumors
inferred← citeshttps://doi.org/10.1007/978-1-59745-172-7_23openalex-snapshot
Current Status of Colorectal Cancer Therapy
inferred← citeshttps://doi.org/10.1007/978-1-59745-184-0_15openalex-snapshot
Normalization of Tumor Vasculature and Microenvironment
inferred← citeshttps://doi.org/10.1007/978-1-59745-184-0_22openalex-snapshot
Antiangiogenesis Agents in Colorectal Cancer
inferred← citeshttps://doi.org/10.1007/978-1-59745-184-0_29openalex-snapshot
Prognostic and Predictive Significance of Surrogate Biomarkers of Angiogenesis
inferred← citeshttps://doi.org/10.1007/978-1-59745-184-0_30openalex-snapshot
Endpoints for the Determination of Efficacy of Antiangiogenic Agents in Clinical Trials
inferred← citeshttps://doi.org/10.1007/978-1-59745-184-0_31openalex-snapshot
The Role of Imaging in the Clinical Development of Antiangiogenic Agents
inferred← citeshttps://doi.org/10.1007/978-1-59745-184-0_4openalex-snapshot
Tumor Endothelial Cell Abnormalities
inferred← citeshttps://doi.org/10.1007/978-1-59745-215-1_5openalex-snapshot
Integration of Antiangiogenic Strategies Into Colorectal Cancer Treatment
inferred← citeshttps://doi.org/10.1007/978-1-59745-222-9_20openalex-snapshot
Problems, Side Effects, and Disappointments in Clinical Cancer Gene Therapy
inferred← citeshttps://doi.org/10.1007/978-1-59745-241-0_2openalex-snapshot
Angiogenic Signalling Pathways
inferred← citeshttps://doi.org/10.1007/978-1-59745-337-0_16openalex-snapshot
Antibody Therapy of Cancer
inferred← citeshttps://doi.org/10.1007/978-1-59745-337-0_7openalex-snapshot
Molecular Targeting of Colorectal Cancer
inferred← citeshttps://doi.org/10.1007/978-1-59745-337-0_8openalex-snapshot
Molecular Targeting in Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.1007/978-1-59745-341-7openalex-snapshot
In Vivo Imaging of Cancer Therapy
inferred← citeshttps://doi.org/10.1007/978-1-59745-341-7_2openalex-snapshot
Preclinical Models of Tumor Growth and Response
inferred← citeshttps://doi.org/10.1007/978-1-59745-341-7_6openalex-snapshot
Computed Tomography Measurements of Perfusion in Cancer Therapy
inferred← citeshttps://doi.org/10.1007/978-1-59745-412-4_20openalex-snapshot
Neurological Complications of Primary Brain Tumors
inferred← citeshttps://doi.org/10.1007/978-1-59745-474-2_18openalex-snapshot
Non-Peptidic Mimetics as Cancer-Sensitizing Agents
inferred← citeshttps://doi.org/10.1007/978-1-60327-044-1_15openalex-snapshot
Future Directions: New Targets
inferred← citeshttps://doi.org/10.1007/978-1-60327-424-1_6openalex-snapshot
Targeted Therapy in Colorectal Cancer
inferred← citeshttps://doi.org/10.1007/978-1-60761-416-6_2openalex-snapshot
Multidrug Resistance in Oncology and Beyond: From Imaging of Drug Efflux Pumps to Cellular Drug Targets
inferred← citeshttps://doi.org/10.1007/978-1-60761-567-5_10openalex-snapshot
Chemotherapy: Concurrent Delivery with Radiation Therapy
inferred← citeshttps://doi.org/10.1007/978-1-60761-567-5_13openalex-snapshot
Radiation Therapy: Adjuvant vs. Neoadjuvant Therapy
inferred← citeshttps://doi.org/10.1007/978-1-62703-586-6_5openalex-snapshot
Polyclonal and Monoclonal Antibodies in Clinic
inferred← citeshttps://doi.org/10.1007/978-1-84628-919-4_8openalex-snapshot
Control of Interstitial Fluid Homeostasis: Roles of Growth Factors and Integrins
inferred← citeshttps://doi.org/10.1007/978-1-84628-947-7_5openalex-snapshot
Systemic Therapy for Non-operable Colorectal Cancer Metastases
inferred← citeshttps://doi.org/10.1007/978-1-84882-756-1_4openalex-snapshot
Chemotherapy Trials for Colorectal Cancer in Advanced Disease: What’s the Current Hypothesis?
inferred← citeshttps://doi.org/10.1007/978-2-287-71655-3_11openalex-snapshot
Optimisation de la stratégie antiangiogénique: association à la radiothérapie
inferred← citeshttps://doi.org/10.1007/978-2-287-71655-3_3openalex-snapshot
Anticorps anti-VEGF: toxicité et modalités ďadministration
inferred← citeshttps://doi.org/10.1007/978-2-8178-0466-8_13openalex-snapshot
Tumor Angiogenesis and Lymphangiogenesis: Microenvironmental Soil for Tumor Progression and Metastatic Dissemination
inferred← citeshttps://doi.org/10.1007/978-2-8178-0527-6_15openalex-snapshot
Indications et gestion des effets secondaires
inferred← citeshttps://doi.org/10.1007/978-2-8178-0527-6_20openalex-snapshot
Biomarqueurs prédictifs d’efficacité
inferred← citeshttps://doi.org/10.1007/978-3-030-23765-3_1openalex-snapshot
Current Development of Monoclonal Antibodies in Cancer Therapy
inferred← citeshttps://doi.org/10.1007/978-3-030-98950-7_2openalex-snapshot
Tissue-Based Biomarkers of Tumor-Vascular Interactions
inferred← citeshttps://doi.org/10.1007/978-3-031-19616-4_10openalex-snapshot
The Role of Pericytes in Tumor Angiogenesis
inferred← citeshttps://doi.org/10.1007/978-3-031-99609-2_13openalex-snapshot
Tumor Microcirculation: Abnormalities and Normalization
inferred← citeshttps://doi.org/10.1007/978-3-319-13896-1_6openalex-snapshot
Conversion and Neoadjuvant Therapies
inferred← citeshttps://doi.org/10.1007/978-3-319-16555-4_9openalex-snapshot
Exploring the Tumor Microenvironment with Nanoparticles
inferred← citeshttps://doi.org/10.1007/978-3-319-17903-2_22openalex-snapshot
Toxicity Management of Renal Cell Cancer Patients on Targeted Therapies
inferred← citeshttps://doi.org/10.1007/978-3-319-21030-8_2openalex-snapshot
Cellular Plasticity, Cancer Stem Cells and Metastasis
inferred← citeshttps://doi.org/10.1007/978-3-319-25670-2_9openalex-snapshot
Different Approaches for Anticancer/Antitumor Therapy
inferred← citeshttps://doi.org/10.1007/978-3-319-31215-6_12-1openalex-snapshot
Cytotoxics and Anti-Angiogenics: Metronomic Therapies
inferred← citeshttps://doi.org/10.1007/978-3-319-31215-6_16-1openalex-snapshot
Anti-angiogenic Targeting in Metastatic Colorectal Cancer Therapy
inferred← citeshttps://doi.org/10.1007/978-3-319-31215-6_3-1openalex-snapshot
The Role of the VEGF Signaling Pathway in Tumor Angiogenesis
inferred← citeshttps://doi.org/10.1007/978-3-319-31215-6_46-1openalex-snapshot
Benefits and Pitfalls of Tumor Vessel Normalization
inferred← citeshttps://doi.org/10.1007/978-3-319-31215-6_7-1openalex-snapshot
Imaging Tumor Angiogenesis
inferred← citeshttps://doi.org/10.1007/978-3-319-33673-2_12openalex-snapshot
Cytotoxics and Anti-angiogenics: Metronomic Therapies
inferred← citeshttps://doi.org/10.1007/978-3-319-33673-2_16openalex-snapshot
Anti-angiogenic Targeting in Metastatic Colorectal Cancer Therapy
inferred← citeshttps://doi.org/10.1007/978-3-319-33673-2_3openalex-snapshot
The Role of the VEGF Signaling Pathway in Tumor Angiogenesis
inferred← citeshttps://doi.org/10.1007/978-3-319-33673-2_46openalex-snapshot
Benefits and Pitfalls of Tumor Vessel Normalization
inferred← citeshttps://doi.org/10.1007/978-3-319-33673-2_7openalex-snapshot
Imaging Tumor Angiogenesis
inferred← citeshttps://doi.org/10.1007/978-3-319-39147-2_3openalex-snapshot
Tissue-Based Biomarkers of Tumor-Vascular Interactions
inferred← citeshttps://doi.org/10.1007/978-3-319-42934-2openalex-snapshot
Current Strategies in Cancer Gene Therapy
inferred← citeshttps://doi.org/10.1007/978-3-319-43217-5_36openalex-snapshot
Should Biological Targeted Agents be Combined with Preoperative Chemoradiation in Rectal Cancer? An Update
inferred← citeshttps://doi.org/10.1007/978-3-319-48824-0_10openalex-snapshot
The Role of the Neuropilins in Tumour Angiogenesis and Tumour Progression
inferred← citeshttps://doi.org/10.1007/978-3-319-55957-5_10openalex-snapshot
Rectal Cancer That Responds to Radiotherapy
inferred← citeshttps://doi.org/10.1007/978-3-319-61115-0_9openalex-snapshot
Therapeutic Implications of Angiogenesis in Cancer
inferred← citeshttps://doi.org/10.1007/978-3-319-94174-5_3openalex-snapshot
Bio-nano: Theranostic at Cellular Level
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