On the public citation graph

p53 and E2f: partners in life and death

0 signed · 607 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/0092-8674(95)90412-3openalex-snapshot

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

inferredcites →https://doi.org/10.1016/0092-8674(95)90513-8openalex-snapshot

A novel form of Epstein-Barr virus latency in normal B cells in vivo

inferredcites →https://doi.org/10.1016/j.ceb.2007.10.006openalex-snapshot

Life and death decisions by the E2F transcription factors

inferredcites →https://doi.org/10.1016/j.devcel.2005.08.015openalex-snapshot

Drosophila E2F1 Has Context-Specific Pro- and Antiapoptotic Properties during Development

inferredcites →https://doi.org/10.1016/j.devcel.2007.10.017openalex-snapshot

Synergistic Function of E2F7 and E2F8 Is Essential for Cell Survival and Embryonic Development

inferredcites →https://doi.org/10.1016/j.molcel.2005.10.017openalex-snapshot

MDM2 Promotes Proteasome-Dependent Ubiquitin-Independent Degradation of Retinoblastoma Protein

inferredcites →https://doi.org/10.1016/j.molcel.2007.05.017openalex-snapshot

Transcriptional Activation of miR-34a Contributes to p53-Mediated Apoptosis

inferredcites →https://doi.org/10.1016/j.molcel.2007.11.036openalex-snapshot

Skp2 Suppresses p53-Dependent Apoptosis by Inhibiting p300

inferredcites →https://doi.org/10.1016/j.molcel.2008.08.031openalex-snapshot

Mdm2 Regulates p53 mRNA Translation through Inhibitory Interactions with Ribosomal Protein L26

inferredcites →https://doi.org/10.1016/j.molmed.2006.02.002openalex-snapshot

E2F1-induced apoptosis: turning killers into therapeutics

inferredcites →https://doi.org/10.1016/j.molmed.2007.03.002openalex-snapshot

Classic and novel roles of p53: prospects for anticancer therapy

inferredcites →https://doi.org/10.1016/j.tcb.2008.08.003openalex-snapshot

E2F – at the crossroads of life and death

inferredcites →https://doi.org/10.1016/j.tibs.2008.08.001openalex-snapshot

The ups and downs of SIRT1

inferredcites →https://doi.org/10.1016/j.virol.2008.09.034openalex-snapshot

The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53

inferredcites →https://doi.org/10.1016/s0021-9258(19)84043-7openalex-snapshot

E2F1 Modulates p38 MAPK Phosphorylation via Transcriptional Regulation of ASK1 and Wip1

inferredcites →https://doi.org/10.1016/s0092-8674(00)00073-8openalex-snapshot

p53AIP1, a Potential Mediator of p53-Dependent Apoptosis, and Its Regulation by Ser-46-Phosphorylated p53

inferredcites →https://doi.org/10.1016/s0092-8674(00)80452-3openalex-snapshot

Tumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19

inferredcites →https://doi.org/10.1016/s0092-8674(01)00524-4openalex-snapshot

Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

inferredcites →https://doi.org/10.1016/s0092-8674(02)00734-1openalex-snapshot

A Senescence Program Controlled by p53 and p16INK4a Contributes to the Outcome of Cancer Therapy

inferredcites →https://doi.org/10.1016/s0959-437x(02)00013-8openalex-snapshot

Tumor suppression by Ink4a–Arf: progress and puzzles

inferredcites →https://doi.org/10.1016/s0960-9822(00)00002-6openalex-snapshot

Tumor spectrum analysis in p53-mutant mice

inferredcites →https://doi.org/10.1016/s0960-9822(01)00659-5openalex-snapshot

ARF Is Not Required for Apoptosis in Rb Mutant Mouse Embryos

inferredcites →https://doi.org/10.1016/s1044-579x(02)00099-8openalex-snapshot

The p53–Mdm2 module and the ubiquitin system

inferredcites →https://doi.org/10.1016/s1097-2765(00)80274-9openalex-snapshot

Mutation of E2f-1 Suppresses Apoptosis and Inappropriate S Phase Entry and Extends Survival of Rb-Deficient Mouse Embryos

inferredcites →https://doi.org/10.1016/s1097-2765(00)80309-3openalex-snapshot

RB Regulates the Stability and the Apoptotic Function of p53 via MDM2

inferredcites →https://doi.org/10.1016/s1097-2765(01)00214-3openalex-snapshot

PUMA, a Novel Proapoptotic Gene, Is Induced by p53

inferredcites →https://doi.org/10.1016/s1097-2765(01)00367-7openalex-snapshot

ASPP Proteins Specifically Stimulate the Apoptotic Function of p53

inferredcites →https://doi.org/10.1016/s1535-6108(02)00085-5openalex-snapshot

E2F transcriptional repressor complexes are critical downstream targets of p19ARF/p53-induced proliferative arrest

inferredcites →https://doi.org/10.1016/s1535-6108(02)00102-2openalex-snapshot

The RB and p53 pathways in cancer

inferredcites →https://doi.org/10.1038/25867openalex-snapshot

p14ARF links the tumour suppressors RB and p53

inferredcites →https://doi.org/10.1038/35036608openalex-snapshot

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation

inferredcites →https://doi.org/10.1038/35036614openalex-snapshot

Role for the p53 homologue p73 in E2F-1-induced apoptosis

inferredcites →https://doi.org/10.1038/35078527openalex-snapshot

Apaf-1 is a transcriptional target for E2F and p53

inferredcites →https://doi.org/10.1038/35096061openalex-snapshot

The INK4a/ARF network in tumour suppression

inferredcites →https://doi.org/10.1038/35106593openalex-snapshot

The E2F1–3 transcription factors are essential for cellular proliferation

inferredcites →https://doi.org/10.1038/356215a0openalex-snapshot

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

inferredcites →https://doi.org/10.1038/375691a0openalex-snapshot

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

inferredcites →https://doi.org/10.1038/375694a0openalex-snapshot

Interaction between the retinoblastoma protein and the oncoprotein MDM2

inferredcites →https://doi.org/10.1038/416560aopenalex-snapshot

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

inferredcites →https://doi.org/10.1038/82617openalex-snapshot

Role of the p53-homologue p73 in E2F1-induced apoptosis

inferredcites →https://doi.org/10.1038/8991openalex-snapshot

Nucleolar Arf sequesters Mdm2 and activates p53

inferredcites →https://doi.org/10.1038/msb.2008.65openalex-snapshot

p53‐repressed miRNAs are involved with E2F in a feed‐forward loop promoting proliferation

inferredcites →https://doi.org/10.1038/nature01116openalex-snapshot

The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response

inferredcites →https://doi.org/10.1038/nature01120openalex-snapshot

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

inferredcites →https://doi.org/10.1038/nature05939openalex-snapshot

A microRNA component of the p53 tumour suppressor network

inferredcites →https://doi.org/10.1038/ncb1123openalex-snapshot

Mitochondrial p53 activates Bak and causes disruption of a Bak–Mcl1 complex

inferredcites →https://doi.org/10.1038/ncb1468openalex-snapshot

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

inferredcites →https://doi.org/10.1038/ncb1730openalex-snapshot

Regulation of autophagy by cytoplasmic p53

inferredcites →https://doi.org/10.1038/ncb868openalex-snapshot

Direct coupling of the cell cycle and cell death machinery by E2F

inferredcites →https://doi.org/10.1038/ncb974openalex-snapshot

Chk2 activates E2F-1 in response to DNA damage

inferredcites →https://doi.org/10.1038/ncb998openalex-snapshot

Differential regulation of E2F1 apoptotic target genes in response to DNA damage

inferredcites →https://doi.org/10.1038/ng0498-360openalex-snapshot

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/−) mice

inferredcites →https://doi.org/10.1038/nrc864openalex-snapshot

Live or let die: the cell's response to p53

inferredcites →https://doi.org/10.1038/nrg2102openalex-snapshot

Network motifs: theory and experimental approaches

inferredcites →https://doi.org/10.1038/nrm2451openalex-snapshot

A complex barcode underlies the heterogeneous response of p53 to stress

inferredcites →https://doi.org/10.1038/nsmb1306openalex-snapshot

The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP

inferredcites →https://doi.org/10.1038/onc.2008.117openalex-snapshot

E2F1 regulates autophagy and the transcription of autophagy genes

inferredcites →https://doi.org/10.1038/onc.2008.164openalex-snapshot

E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines

inferredcites →https://doi.org/10.1038/sj.cdd.4401536openalex-snapshot

Apoptosis-stimulating protein of p53-2 (ASPP2/53BP2L) is an E2F target gene

inferredcites →https://doi.org/10.1038/sj.cdd.4401562openalex-snapshot

ASPP1 and ASPP2 are new transcriptional targets of E2F

inferredcites →https://doi.org/10.1038/sj.cdd.4401575openalex-snapshot

Novel link between E2F and p53: proapoptotic cofactors of p53 are transcriptionally upregulated by E2F

inferredcites →https://doi.org/10.1038/sj.cdd.4401912openalex-snapshot

Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4

inferredcites →https://doi.org/10.1038/sj.cdd.4402108openalex-snapshot

p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death

inferredcites →https://doi.org/10.1038/sj.emboj.7600735openalex-snapshot

Cell cycle‐dependent nuclear retention of p53 by E2F1 requires phosphorylation of p53 at Ser315

inferredcites →https://doi.org/10.1038/sj.emboj.7600836openalex-snapshot

Distinct E2F‐mediated transcriptional program regulates p14 ARF gene expression

inferredcites →https://doi.org/10.1038/sj.emboj.7601825openalex-snapshot

The candidate tumor suppressor BTG3 is a transcriptional target of p53 that inhibits E2F1

inferredcites →https://doi.org/10.1038/sj.onc.1201666openalex-snapshot

Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development

inferredcites →https://doi.org/10.1038/sj.onc.1203540openalex-snapshot

Stress signals induce transcriptionally inactive E2F-1 independently of p53 and Rb

inferredcites →https://doi.org/10.1038/sj.onc.1204067openalex-snapshot

Negative regulation of bcl-2 expression by p53 in hematopoietic cells

inferredcites →https://doi.org/10.1038/sj.onc.1204220openalex-snapshot

Human ARF binds E2F1 and inhibits its transcriptional activity

inferredcites →https://doi.org/10.1038/sj.onc.1204892openalex-snapshot

Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1

inferredcites →https://doi.org/10.1038/sj.onc.1205157openalex-snapshot

Direct repression of the Mcl-1 promoter by E2F1

inferredcites →https://doi.org/10.1038/sj.onc.1205524openalex-snapshot

p14ARF regulates E2F activity

inferredcites →https://doi.org/10.1038/sj.onc.1206144openalex-snapshot

ATM is a target for positive regulation by E2F-1

inferredcites →https://doi.org/10.1038/sj.onc.1206845openalex-snapshot

Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53

inferredcites →https://doi.org/10.1038/sj.onc.1207274openalex-snapshot

Amplification and overexpression of E2F3 in human bladder cancer

inferredcites →https://doi.org/10.1038/sj.onc.1207571openalex-snapshot

Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle

inferredcites →https://doi.org/10.1038/sj.onc.1207749openalex-snapshot

E2F3 amplification and overexpression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer

inferredcites →https://doi.org/10.1038/sj.onc.1207800openalex-snapshot

Transcription factor E2F3 overexpressed in prostate cancer independently predicts clinical outcome

inferredcites →https://doi.org/10.1038/sj.onc.1208612openalex-snapshot

The E2F transcriptional network: old acquaintances with new faces

inferredcites →https://doi.org/10.1038/sj.onc.1208619openalex-snapshot

Pocket proteins and cell cycle control

inferredcites →https://doi.org/10.1038/sj.onc.1208814openalex-snapshot

Stabilization of E2F1 protein by MDM2 through the E2F1 ubiquitination pathway

inferredcites →https://doi.org/10.1038/sj.onc.1209286openalex-snapshot

F-box protein Skp2: a novel transcriptional target of E2F

inferredcites →https://doi.org/10.1038/sj.onc.1209946openalex-snapshot

E2F3 is the main target gene of the 6p22 amplicon with high specificity for human bladder cancer

inferredcites →https://doi.org/10.1038/sj.onc.1210136openalex-snapshot

Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1

inferredcites →https://doi.org/10.1038/sj.onc.1210293openalex-snapshot

MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells

inferredcites →https://doi.org/10.1038/sj.onc.1210294openalex-snapshot

Transcription regulation by mutant p53

inferredcites →https://doi.org/10.1073/pnas.0502857102openalex-snapshot

The coordinate regulation of the p53 and mTOR pathways in cells

inferredcites →https://doi.org/10.1073/pnas.0707351104openalex-snapshot

Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells

inferredcites →https://doi.org/10.1073/pnas.081061398openalex-snapshot

p19ARF targets certain E2F species for degradation

inferredcites →https://doi.org/10.1073/pnas.201208798openalex-snapshot

Expression of bbc3 , a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals

inferredcites →https://doi.org/10.1073/pnas.91.9.3602openalex-snapshot

p53 and E2F-1 cooperate to mediate apoptosis.

inferredcites →https://doi.org/10.1073/pnas.95.15.8858openalex-snapshot

Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53

inferredcites →https://doi.org/10.1073/pnas.95.20.11945openalex-snapshot

pRB plays an essential role in cell cycle arrest induced by DNA damage

inferredcites →https://doi.org/10.1074/jbc.m005101200openalex-snapshot

p130/E2F4 Binds to and Represses the cdc2 Promoter in Response to p53

inferredcites →https://doi.org/10.1074/jbc.m210327200openalex-snapshot

E2F Mediates Sustained G2 Arrest and Down-regulation of Stathmin and AIM-1 Expression in Response to Genotoxic Stress

inferredcites →https://doi.org/10.1074/jbc.m312866200openalex-snapshot

Up-regulation of Bcl-2 Homology 3 (BH3)-only Proteins by E2F1 Mediates Apoptosis

inferredcites →https://doi.org/10.1074/jbc.m400376200openalex-snapshot

The Proapoptotic Gene SIVA Is a Direct Transcriptional Target for the Tumor Suppressors p53 and E2F1

inferredcites →https://doi.org/10.1074/jbc.m402403200openalex-snapshot

Specific Role for p300/CREB-binding Protein-associated Factor Activity in E2F1 Stabilization in Response to DNA Damage

inferredcites →https://doi.org/10.1074/jbc.m406062200openalex-snapshot

The Central Acidic Domain of MDM2 Is Critical in Inhibition of Retinoblastoma-mediated Suppression of E2F and Cell Growth

inferredcites →https://doi.org/10.1074/jbc.m604152200openalex-snapshot

Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 Is Essential for G1/S Progression and Cellular Transformation

inferredcites →https://doi.org/10.1093/emboj/21.10.2383openalex-snapshot

Human SIR2 deacetylates p53 and antagonizes PML/p53‐induced cellular senescence

inferredcites →https://doi.org/10.1101/gad.1196704openalex-snapshot

Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics

inferredcites →https://doi.org/10.1101/gad.1221004openalex-snapshot

p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2

inferredcites →https://doi.org/10.1101/gad.14.3.278openalex-snapshot

Chk2/hCds1 functions as a DNA damage checkpoint in G1by stabilizing p53

inferredcites →https://doi.org/10.1101/gad.14.6.690openalex-snapshot

E2f3 is critical for normal cellular proliferation

inferredcites →https://doi.org/10.1101/gad.843200openalex-snapshot

Targeted disruption of the three Rb-related genes leads to loss of G 1 control and immortalization

inferredcites →https://doi.org/10.1101/gad.847700openalex-snapshot

Ablation of the Retinoblastoma gene family deregulates G1 control causing immortalization and increased cell turnover under growth-restricting conditions

inferredcites →https://doi.org/10.1101/gad.858801openalex-snapshot

E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos

inferredcites →https://doi.org/10.1126/science.1101731openalex-snapshot

Nutrient Availability Regulates SIRT1 Through a Forkhead-Dependent Pathway

inferredcites →https://doi.org/10.1126/science.281.5383.1674openalex-snapshot

Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage

inferredcites →https://doi.org/10.1126/science.281.5383.1677openalex-snapshot

Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

inferredcites →https://doi.org/10.1126/science.288.5468.1053openalex-snapshot

Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis

inferredcites →https://doi.org/10.1128/mcb.02147-05openalex-snapshot

E2f1, E2f2, and E2f3 Control E2F Target Expression and Cellular Proliferation via a p53-Dependent Negative Feedback Loop

inferredcites →https://doi.org/10.1128/mcb.02246-06openalex-snapshot

BNIP3 Is an RB/E2F Target Gene Required for Hypoxia-Induced Autophagy

inferredcites →https://doi.org/10.1128/mcb.18.11.6457openalex-snapshot

The Human ARF Cell Cycle Regulatory Gene Promoter Is a CpG Island Which Can Be Silenced by DNA Methylation and Down-Regulated by Wild-Type p53

inferredcites →https://doi.org/10.1128/mcb.19.5.3704openalex-snapshot

Transcription Factor E2F-1 Is Upregulated in Response to DNA Damage in a Manner Analogous to That of p53

inferredcites →https://doi.org/10.1128/mcb.20.12.4210-4223.2000openalex-snapshot

p53 Regulation of G 2 Checkpoint Is Retinoblastoma Protein Dependent

inferredcites →https://doi.org/10.1128/mcb.20.6.2186-2197.2000openalex-snapshot

Apoptotic and Growth-Promoting Activity of E2F Modulated by MDM2

inferredcites →https://doi.org/10.1128/mcb.22.1.370-377.2002openalex-snapshot

p19ARF Is Dispensable for Oncogenic Stress-Induced p53-Mediated Apoptosis and Tumor Suppression In Vivo

inferredcites →https://doi.org/10.1128/mcb.22.1.78-93.2002openalex-snapshot

Novel Function of the Cyclin A Binding Site of E2F in Regulating p53-Induced Apoptosis in Response to DNA Damage

inferredcites →https://doi.org/10.1128/mcb.22.15.5281-5295.2002openalex-snapshot

PIN1 Is an E2F Target Gene Essential for Neu/Ras-Induced Transformation of Mammary Epithelial Cells

inferredcites →https://doi.org/10.1128/mcb.22.15.5308-5318.2002openalex-snapshot

E2F1 Induces Phosphorylation of p53 That Is Coincident with p53 Accumulation and Apoptosis

inferredcites →https://doi.org/10.1128/mcb.22.5.1360-1368.2002openalex-snapshot

ARF Differentially Modulates Apoptosis Induced by E2F1 and Myc

inferredcites →https://doi.org/10.1128/mcb.24.7.2968-2977.2004openalex-snapshot

Apoptosis Associated with Deregulated E2F Activity Is Dependent on E2F1 and Atm/Nbs1/Chk2

inferredcites →https://doi.org/10.1128/mcb.4.9.1689openalex-snapshot

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

inferredcites →https://doi.org/10.1158/0008-5472.can-06-2178openalex-snapshot

Retinoblastoma Pathway Defects Show Differential Ability to Activate the Constitutive DNA Damage Response in Human Tumorigenesis

inferredcites →https://doi.org/10.1158/1541-7786.203.2.4openalex-snapshot

E2F1 Uses the ATM Signaling Pathway to Induce p53 and Chk2 Phosphorylation and Apoptosis

inferredcites →https://doi.org/10.2174/1566524010606070731openalex-snapshot

Putting the Oncogenic and Tumor Suppressive Activities of E2F into Context

inferredcites →https://doi.org/10.2174/1566524010606070739openalex-snapshot

Distinct and Overlapping Roles for E2F Family Members in Transcription, Proliferation and Apoptosis

inferredcites →https://doi.org/10.3892/ijo_00000267openalex-snapshot

The MDM2 antagonist nutlin-3 sensitizes p53-null neuroblastoma cells to doxorubicin via E2F1 and TAp73

inferredcites →https://doi.org/10.4161/cc.4.7.1784openalex-snapshot

Regulation of E2F-1 after DNA Damage by p300-Mediated Acetylation and Ubiquitination

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.5281/zenodo.4381012openalex-extracted

DETERMINATION OF GENOTОXIC EFFECTS OF SOME FOOD ADDITIVES ON SOME HUMAN CANCER CELLS BY FLOW CYTOMETRY ANALYSIS

inferred← citeshttps://doi.org/10.1002/9781118005743.ch1openalex-snapshot

Epigenetic Modulation of Cell Cycle: An Overview

inferred← citeshttps://doi.org/10.1002/9781118140574.ch16openalex-snapshot

Dioxin Activated AHR and Cancer in Laboratory Animals

inferred← citeshttps://doi.org/10.1002/advs.202104491openalex-snapshot

Genetic Aberrations and Interaction of NEK2 and TP53 Accelerate Aggressiveness of Multiple Myeloma

inferred← citeshttps://doi.org/10.1002/advs.202204599openalex-snapshot

LncRNA LIMp27 Regulates the DNA Damage Response through p27 in p53‐Defective Cancer Cells

inferred← citeshttps://doi.org/10.1002/cbf.1818openalex-snapshot

Acute loss of DP1, but not DP2, induces p53 mRNA and augments p21Waf1/Cip1 and senescence

inferred← citeshttps://doi.org/10.1002/embj.201386917openalex-snapshot

Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging

inferred← citeshttps://doi.org/10.1002/gcc.22395openalex-snapshot

Characterizing Genetic Transitions of Copy Number Alterations and Allelic Imbalances in Oral Tongue Carcinoma Metastasis

inferred← citeshttps://doi.org/10.1002/gcc.22703openalex-snapshot

CINSARC signature as a prognostic marker for clinical outcome in sarcomas and beyond

inferred← citeshttps://doi.org/10.1002/hed.25057openalex-snapshot

Comprehensive review of genetic factors contributing to head and neck squamous cell carcinoma development in low‐risk, nontraditional patients

inferred← citeshttps://doi.org/10.1002/ijc.26501openalex-snapshot

The JmjC domain‐containing histone demethylase KDM3A is a positive regulator of the G 1 /S transition in cancer cells via transcriptional regulation of the HOXA1 gene

inferred← citeshttps://doi.org/10.1002/jcb.24194openalex-snapshot

E2F1‐dependent pathways are involved in amonafide analogue 7‐d‐induced DNA damage, G2/M arrest, and apoptosis in p53‐deficient K562 cells

inferred← citeshttps://doi.org/10.1002/jcb.29324openalex-snapshot

Resistance of human primary mesenchymal stem cells to cytotoxic effects of nutlin‐3 in vitro

inferred← citeshttps://doi.org/10.1002/jcp.24076openalex-snapshot

Nanog regulates molecules involved in stemness and cell cycle‐signaling pathway for maintenance of pluripotency of P19 embryonal carcinoma stem cells

inferred← citeshttps://doi.org/10.1002/jcp.24821openalex-snapshot

miR‐203 Is a Direct Transcriptional Target of E2F1 and Causes G1 Arrest in Esophageal Cancer Cells

inferred← citeshttps://doi.org/10.1002/jcp.25336openalex-snapshot

PERK Integrates Oncogenic Signaling and Cell Survival During Cancer Development

inferred← citeshttps://doi.org/10.1002/jcp.27798openalex-snapshot

The effects of Nutlin‐3 on morphology, cellular proliferation, and apoptosis in rat primary mesenchymal stem cells

inferred← citeshttps://doi.org/10.1002/jcp.28051openalex-snapshot

Loss of ENT1 increases cell proliferation in the annulus fibrosus of the intervertebral disc

inferred← citeshttps://doi.org/10.1002/jnr.23060openalex-snapshot

Expression pattern of ataxia telangiectasia mutated (ATM), p53, Akt, and glycogen synthase kinase‐3β in the striatum of rats treated with 3‐nitropropionic acid

inferred← citeshttps://doi.org/10.1002/mc.21882openalex-snapshot

Combined effects of E2F1 and E2F2 polymorphisms on risk and early onset of squamous cell carcinoma of the head and neck

inferred← citeshttps://doi.org/10.1002/mc.22576openalex-snapshot

A functional variant at the miRNA binding site in E2F1 gene is associated with risk and tumor HPV16 status of oropharynx squamous cell carcinoma

inferred← citeshttps://doi.org/10.1002/mc.22595openalex-snapshot

E2F transcription factor 2 variants as predictive biomarkers for recurrence risk in patients with squamous cell carcinoma of the oropharynx

inferred← citeshttps://doi.org/10.1002/path.2783openalex-snapshot

Regulation of tissue‐ and stimulus‐specific cell fate decisions by p53 in vivo

inferred← citeshttps://doi.org/10.1002/path.4321openalex-snapshot

Effects of TP53 mutational status on gene expression patterns across 10 human cancer types

inferred← citeshttps://doi.org/10.1002/path.4402openalex-snapshot

A genetically engineered mouse model developing rapid progressive pancreatic ductal adenocarcinoma

inferred← citeshttps://doi.org/10.1002/path.5347openalex-snapshot

BTK inhibitors synergise with 5‐FU to treat drug‐resistant TP53‐null colon cancers

inferred← citeshttps://doi.org/10.1002/path.6295openalex-snapshot

Identification of Ppy ‐lineage cells as a novel origin of pancreatic ductal adenocarcinoma

inferred← citeshttps://doi.org/10.1007/978-1-0716-0301-7_4openalex-snapshot

MSTD for Detecting Topological Domains from 3D Genomic Maps

inferred← citeshttps://doi.org/10.1007/978-1-4614-3685-0_27openalex-snapshot

Prerequisite Genetic Traits for Metastasis

inferred← citeshttps://doi.org/10.1007/978-1-4614-9557-4_5openalex-snapshot

DNA Damage Caused by Oral Malodorous Compounds in Periodontal Cells In Vitro: Novel Carcinogenic Pathway

inferred← citeshttps://doi.org/10.1007/978-1-4939-0888-2_10openalex-snapshot

Cell Cycle Regulation During Viral Infection

inferred← citeshttps://doi.org/10.1007/978-1-61779-407-0_9openalex-snapshot

Targeting Apoptotic Pathways in Melanoma

inferred← citeshttps://doi.org/10.1007/978-3-319-52354-5_2openalex-snapshot

HSP90-Stabilized MIF in Oncogenesis and Cell Growth Control

inferred← citeshttps://doi.org/10.1007/978-4-431-55873-6_18openalex-snapshot

Molecular Insights into the Regulation of Apoptosis and Cellular Senescence and Their Implications for Cancer

inferred← citeshttps://doi.org/10.1007/978-94-007-5590-1openalex-snapshot

MicroRNA Cancer Regulation: Advanced Concepts, Bioinformatics and Systems Biology Tools

inferred← citeshttps://doi.org/10.1007/978-94-007-5590-1_8openalex-snapshot

The E2F1-miRNA Cancer Progression Network

inferred← citeshttps://doi.org/10.1007/978-94-017-9211-0_12openalex-snapshot

MDM2 Overexpression, Activation of Signaling Networks, and Cell Proliferation

inferred← citeshttps://doi.org/10.1007/978-94-024-1577-3_3openalex-snapshot

MicroRNA Function of Some Life Process in the Gene Network

inferred← citeshttps://doi.org/10.1007/978-981-15-1067-0_9openalex-snapshot

MicroRNAs in Cancer: From Diagnosis to Therapeutics

inferred← citeshttps://doi.org/10.1007/s00018-011-0666-xopenalex-snapshot

S-phase-coupled apoptosis in tumor suppression

inferred← citeshttps://doi.org/10.1007/s00109-011-0775-xopenalex-snapshot

MiR-106a inhibits glioma cell growth by targeting E2F1 independent of p53 status

inferred← citeshttps://doi.org/10.1007/s00717-009-0360-7openalex-snapshot

Genetik des Aderhautmelanoms

inferred← citeshttps://doi.org/10.1007/s10068-017-0252-6openalex-snapshot

Inhibitory effect of vitamin C on intrinsic aging in human dermal fibroblasts and hairless mice

inferred← citeshttps://doi.org/10.1007/s10495-010-0456-1openalex-snapshot

Regulating the genome surveillance system: miRNAs and the p53 super family

inferred← citeshttps://doi.org/10.1007/s10495-013-0850-6openalex-snapshot

AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts

inferred← citeshttps://doi.org/10.1007/s10495-015-1143-zopenalex-snapshot

Multifaceted role of prohibitin in cell survival and apoptosis

inferred← citeshttps://doi.org/10.1007/s10522-017-9698-4openalex-snapshot

Molecular connections of obesity and aging: a focus on adipose protein 53 and retinoblastoma protein

inferred← citeshttps://doi.org/10.1007/s10555-024-10226-2openalex-snapshot

TRIM-endous functional network of tripartite motif 29 (TRIM29) in cancer progression and beyond

inferred← citeshttps://doi.org/10.1007/s10571-017-0563-4openalex-snapshot

Ameliorating Effect of Osteopontin on H2O2-Induced Apoptosis of Human Oligodendrocyte Progenitor Cells

inferred← citeshttps://doi.org/10.1007/s10637-012-9882-yopenalex-snapshot

The non-genotoxic activator of the p53 pathway Nutlin-3 shifts the balance between E2F7 and E2F1 transcription factors in leukemic cells

inferred← citeshttps://doi.org/10.1007/s11010-012-1310-2openalex-snapshot

Apigenin induces apoptosis via extrinsic pathway, inducing p53 and inhibiting STAT3 and NFκB signaling in HER2-overexpressing breast cancer cells

inferred← citeshttps://doi.org/10.1007/s11010-016-2796-9openalex-snapshot

The PI3K/Akt/mTOR pathway regulates the replicative senescence of human VSMCs

inferred← citeshttps://doi.org/10.1007/s11010-024-05063-4openalex-snapshot

The E2F family: a ray of dawn in cardiomyopathy

inferred← citeshttps://doi.org/10.1007/s11033-026-12179-xopenalex-snapshot

Pro-apoptotic and cell cycle-modulating effects of lobaric and rhizocarpic acids in human leukemic cell lines

inferred← citeshttps://doi.org/10.1007/s11064-015-1642-xopenalex-snapshot

Astroglial U87 Cells Protect Neuronal SH-SY5Y Cells from Indirect Effect of Radiation by Reducing DNA Damage and Inhibiting Fas Mediated Apoptotic Pathway in Coculture System

inferred← citeshttps://doi.org/10.1007/s12017-021-08667-xopenalex-snapshot

Receptor-Interacting Protein 140 Enhanced Temozolomide-Induced Cellular Apoptosis Through Regulation of E2F1 in Human Glioma Cell Lines

inferred← citeshttps://doi.org/10.1007/s12032-013-0653-1openalex-snapshot

Triple-negative breast cancer: new perspectives for novel therapies

inferred← citeshttps://doi.org/10.1007/s12253-017-0215-5openalex-snapshot

Nutlin-3, an Antagonist of MDM2, Enhances the Radiosensitivity of Esophageal Squamous Cancer with Wild-Type p53

inferred← citeshttps://doi.org/10.1007/s12640-011-9277-4openalex-snapshot

Role of Cell Cycle Re-Entry in Neurons: A Common Apoptotic Mechanism of Neuronal Cell Death

inferred← citeshttps://doi.org/10.1007/s13277-013-1359-xopenalex-snapshot

Association between TP53 Arg72Pro polymorphism and thyroid carcinoma risk

inferred← citeshttps://doi.org/10.1007/s13277-014-2744-9openalex-snapshot

Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells

inferred← citeshttps://doi.org/10.1007/s13277-015-3938-5openalex-snapshot

Combined analysis identifies six genes correlated with augmented malignancy from non-small cell to small cell lung cancer

inferred← citeshttps://doi.org/10.1007/s13752-025-00498-4openalex-snapshot

The Coordination of Pathways in Metazoans: An Integrated Framework

inferred← citeshttps://doi.org/10.1007/s13770-024-00660-2openalex-snapshot

Rapamycin Attenuates H2O2-Induced Oxidative Stress-Related Senescence in Human Skin Fibroblasts

inferred← citeshttps://doi.org/10.1016/b978-0-12-407173-5.00004-2openalex-snapshot

The Transcription Factor FOXM1 (Forkhead box M1)

inferred← citeshttps://doi.org/10.1016/b978-0-323-47674-4.00089-xopenalex-snapshot

Sarcomas of Bone

inferred← citeshttps://doi.org/10.1016/b978-1-4557-2865-7.00092-8openalex-snapshot

Sarcomas of Bone

inferred← citeshttps://doi.org/10.1016/b978-1-4557-4066-6.00003-2openalex-snapshot

Tumor Suppressor Genes

inferred← citeshttps://doi.org/10.1016/bs.acr.2017.06.001openalex-snapshot

The Enigma of miRNA Regulation in Cancer

inferred← citeshttps://doi.org/10.1016/bs.apcsb.2016.10.003openalex-snapshot

Transcription Factors in Breast Cancer—Lessons From Recent Genomic Analyses and Therapeutic Implications

inferred← citeshttps://doi.org/10.1016/bs.ctdb.2018.10.006openalex-snapshot

Transcriptional networks orchestrating programmed cell death during plant development

inferred← citeshttps://doi.org/10.1016/j.aspetd.2025.100002openalex-snapshot

NEK2 inhibition alleviates lipopolysaccharide-induced endothelial injury

inferred← citeshttps://doi.org/10.1016/j.bbagrm.2014.09.015openalex-snapshot

Transcriptional activation of PRMT5 by NF-Y is required for cell growth and negatively regulated by the PKC/c-Fos signaling in prostate cancer cells

inferred← citeshttps://doi.org/10.1016/j.bbalip.2016.09.009openalex-snapshot

Stearoyl CoA desaturase-1: New insights into a central regulator of cancer metabolism

inferred← citeshttps://doi.org/10.1016/j.bbamcr.2021.118953openalex-snapshot

Regulation of p53 and NF-κB transactivation activities by DGKζ in catalytic activity-dependent and -independent manners

inferred← citeshttps://doi.org/10.1016/j.bbapap.2013.05.007openalex-snapshot

Hybrid modeling of the crosstalk between signaling and transcriptional networks using ordinary differential equations and multi-valued logic

inferred← citeshttps://doi.org/10.1016/j.bbapap.2013.06.022openalex-snapshot

Dynamic analysis of the combinatorial regulation involving transcription factors and microRNAs in cell fate decisions

inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.08.040openalex-snapshot

Loss of circadian protein TIMELESS accelerates the progression of cellular senescence

inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.11.103openalex-snapshot

Valproic acid suppresses Warburg effect and tumor progression in neuroblastoma

inferred← citeshttps://doi.org/10.1016/j.bbrc.2023.04.092openalex-snapshot

The TFDP1 gene coding for DP1, the heterodimeric partner of the transcription factor E2F, is a target of deregulated E2F

inferred← citeshttps://doi.org/10.1016/j.biocel.2010.12.013openalex-snapshot

Single-walled carbon nanotube induction of rat aortic endothelial cell apoptosis: Reactive oxygen species are involved in the mitochondrial pathway

inferred← citeshttps://doi.org/10.1016/j.biocel.2012.06.034openalex-snapshot

Ei24-deficiency attenuates protein kinase Cα signaling and skin carcinogenesis in mice

inferred← citeshttps://doi.org/10.1016/j.canlet.2013.09.010openalex-snapshot

Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides

inferred← citeshttps://doi.org/10.1016/j.canlet.2015.04.015openalex-snapshot

The regulation of radiosensitivity by p53 and its acetylation

inferred← citeshttps://doi.org/10.1016/j.canlet.2022.215870openalex-snapshot

Novel insights into RB1 mutation

inferred← citeshttps://doi.org/10.1016/j.ccr.2011.04.017openalex-snapshot

Mad2 Is a Critical Mediator of the Chromosome Instability Observed upon Rb and p53 Pathway Inhibition

inferred← citeshttps://doi.org/10.1016/j.ccr.2012.07.014openalex-snapshot

Integrative Analysis Reveals an Outcome-Associated and Targetable Pattern of p53 and Cell Cycle Deregulation in Diffuse Large B Cell Lymphoma

inferred← citeshttps://doi.org/10.1016/j.ceb.2010.07.013openalex-snapshot

Oncogene-induced senescence: the bright and dark side of the response

inferred← citeshttps://doi.org/10.1016/j.cell.2011.12.027openalex-snapshot

Mitochondrial Stress Engages E2F1 Apoptotic Signaling to Cause Deafness

inferred← citeshttps://doi.org/10.1016/j.cell.2020.09.062openalex-snapshot

M. tuberculosis Reprograms Hematopoietic Stem Cells to Limit Myelopoiesis and Impair Trained Immunity

inferred← citeshttps://doi.org/10.1016/j.cell.2023.06.022openalex-snapshot

Modeling epigenetic lesions that cause gliomas

inferred← citeshttps://doi.org/10.1016/j.cell.2023.07.004openalex-snapshot

Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer

inferred← citeshttps://doi.org/10.1016/j.cellimm.2026.105063openalex-snapshot

Thymidine induces macrophage M1 polarization in radiation-induced-lung-injury by ATF3/p38 pathway

inferred← citeshttps://doi.org/10.1016/j.cellsig.2010.09.003openalex-snapshot

E2F1 inhibits MDM2 expression in a p53-dependent manner

inferred← citeshttps://doi.org/10.1016/j.cellsig.2011.08.022openalex-snapshot

Going out of the brain: Non-nervous system physiological and pathological functions of Cdk5

inferred← citeshttps://doi.org/10.1016/j.cellsig.2016.11.016openalex-snapshot

COMMD9 promotes TFDP1/E2F1 transcriptional activity via interaction with TFDP1 in non-small cell lung cancer

inferred← citeshttps://doi.org/10.1016/j.celrep.2019.07.001openalex-snapshot

Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas

inferred← citeshttps://doi.org/10.1016/j.chom.2014.10.005openalex-snapshot

A Noncanonical Role for the CKI-RB-E2F Cell-Cycle Signaling Pathway in Plant Effector-Triggered Immunity

inferred← citeshttps://doi.org/10.1016/j.chom.2015.10.001openalex-snapshot

Cell-Cycle Regulators and Cell Death in Immunity

inferred← citeshttps://doi.org/10.1016/j.compbiomed.2016.08.004openalex-snapshot

Identification of informative genes and pathways using an improved penalized support vector machine with a weighting scheme

inferred← citeshttps://doi.org/10.1016/j.critrevonc.2015.08.006openalex-snapshot

TP53 dysfunction in diffuse large B-cell lymphoma

inferred← citeshttps://doi.org/10.1016/j.critrevonc.2015.08.019openalex-snapshot

Critical review about MDM2 in cancer: Possible role in malignant mesothelioma and implications for treatment

inferred← citeshttps://doi.org/10.1016/j.csbj.2025.07.023openalex-snapshot

Anticancer effects and mechanisms of Pulsatilla chinensis , Bupleurum chinense and Polyporus umbellatus on human lung carcinoma and hepatoma cells

inferred← citeshttps://doi.org/10.1016/j.devcel.2013.10.002openalex-snapshot

Loss of dE2F Compromises Mitochondrial Function

inferred← citeshttps://doi.org/10.1016/j.diff.2020.02.001openalex-snapshot

The RB gene family controls the maturation state of the EndoC-βH2 human pancreatic β-cells

inferred← citeshttps://doi.org/10.1016/j.dnarep.2012.11.002openalex-snapshot

Cell-cycle and DNA damage regulation of the DNA mismatch repair protein Msh2 occurs at the transcriptional and post-transcriptional level

inferred← citeshttps://doi.org/10.1016/j.drup.2010.06.001openalex-snapshot

Translating DNA damage into cancer cell death—A roadmap for E2F1 apoptotic signalling and opportunities for new drug combinations to overcome chemoresistance

inferred← citeshttps://doi.org/10.1016/j.drup.2010.11.001openalex-snapshot

New frontiers in the treatment of liposarcoma, a therapeutically resistant malignant cohort

inferred← citeshttps://doi.org/10.1016/j.drup.2012.01.004openalex-snapshot

Starvation, detoxification, and multidrug resistance in cancer therapy

inferred← citeshttps://doi.org/10.1016/j.ebiom.2016.10.026openalex-snapshot

H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer

inferred← citeshttps://doi.org/10.1016/j.ejcb.2016.06.007openalex-snapshot

Causes and consequences of nuclear envelope alterations in tumour progression

inferred← citeshttps://doi.org/10.1016/j.ejphar.2024.177218openalex-snapshot

Deciphering TGF-β1's role in drug resistance and leveraging plant bioactives for cancer therapy

inferred← citeshttps://doi.org/10.1016/j.exer.2022.109205openalex-snapshot

Localization of phosphatidylinositol phosphate 5 kinase γ, phospholipase β3 and diacylglycerol kinase ζ in corneal epithelium in comparison with conjunctival epithelium of mice

inferred← citeshttps://doi.org/10.1016/j.febslet.2013.08.009openalex-snapshot

E2F1 activates p53 transcription through its distal site and participates in apoptosis induction in HPV‐positive cells

inferred← citeshttps://doi.org/10.1016/j.febslet.2014.01.040openalex-snapshot

VRK1 interacts with p53 forming a basal complex that is activated by UV‐induced DNA damage

inferred← citeshttps://doi.org/10.1016/j.febslet.2014.10.005openalex-snapshot

Zinc finger protein ZBTB20 promotes cell proliferation in non‐small cell lung cancer through repression of FoxO1

inferred← citeshttps://doi.org/10.1016/j.fertnstert.2014.09.021openalex-snapshot

Genomic and genetic variation in E2F transcription factor-1 in men with nonobstructive azoospermia

inferred← citeshttps://doi.org/10.1016/j.gendis.2020.07.003openalex-snapshot

Tumor suppressor p53 cross-talks with TRIM family proteins

inferred← citeshttps://doi.org/10.1016/j.gene.2014.09.052openalex-snapshot

miR-15/16 complex targets p70S6 kinase1 and controls cell proliferation in MDA-MB-231 breast cancer cells

inferred← citeshttps://doi.org/10.1016/j.gene.2025.149365openalex-snapshot

Exploring the dual role of SIVA1 in cancer biology

inferred← citeshttps://doi.org/10.1016/j.genrep.2018.06.012openalex-snapshot

Functions and epigenetic aspects of miR-15/16: Possible future cancer therapeutics

inferred← citeshttps://doi.org/10.1016/j.genrep.2019.100476openalex-snapshot

E2F1 gene variant rs2071054 is a risk factor for head and neck and cervical cancers: A pilot study

inferred← citeshttps://doi.org/10.1016/j.genrep.2020.100815openalex-snapshot

Enhanced transcription activity of histone acetyltransferase HBO1 after genotoxic stress

inferred← citeshttps://doi.org/10.1016/j.genrep.2023.101750openalex-snapshot

Hydroxytyrosol's effect on the expression of apoptosis and oxidative stress related genes in BE (2)-C neuroblastoma cell line

inferred← citeshttps://doi.org/10.1016/j.hermed.2024.100974openalex-snapshot

The Effect of Nigella sativa Linn. Extract on E2F1 Expression and Apoptosis in Retinoblastoma Y79 Cells

inferred← citeshttps://doi.org/10.1016/j.isci.2024.111118openalex-snapshot

Drosophila p53 tumor suppressor directly activates conserved asymmetric stem cell division regulators

inferred← citeshttps://doi.org/10.1016/j.jbc.2026.113590openalex-snapshot

EAG1 channel is a central regulator of tumor growth and metastasis in A549 non-small cell lung cancer cells

inferred← citeshttps://doi.org/10.1016/j.jbior.2013.08.007openalex-snapshot

DGKζ under stress conditions: “To be nuclear or cytoplasmic, that is the question”

inferred← citeshttps://doi.org/10.1016/j.jbior.2015.09.009openalex-snapshot

Reciprocal regulation of p53 and NF-κB by diacylglycerol kinase ζ

inferred← citeshttps://doi.org/10.1016/j.jbior.2017.09.010openalex-snapshot

DGKζ ablation engenders upregulation of p53 level in the spleen upon whole-body ionizing radiation

inferred← citeshttps://doi.org/10.1016/j.jep.2023.116815openalex-snapshot

Study on the material basis and action mechanisms of sophora davidii (Franch.) skeels flower extract in the treatment of non-small cell lung cancer

inferred← citeshttps://doi.org/10.1016/j.jgo.2013.09.001openalex-snapshot

Evaluating the physiological reserves of older patients with cancer: The value of potential biomarkers of aging?

inferred← citeshttps://doi.org/10.1016/j.jtho.2019.01.028openalex-snapshot

Checkpoint Kinase 1 Inhibition Enhances Cisplatin Cytotoxicity and Overcomes Cisplatin Resistance in SCLC by Promoting Mitotic Cell Death

inferred← citeshttps://doi.org/10.1016/j.juro.2015.04.090openalex-snapshot

A Murine Model of K-RAS and β-Catenin Induced Renal Tumors Expresses High Levels of E2F1 and Resembles Human Wilms Tumor

inferred← citeshttps://doi.org/10.1016/j.lfs.2014.01.063openalex-snapshot

The roles of p53R2 in cancer progression based on the new function of mutant p53 and cytoplasmic p21

inferred← citeshttps://doi.org/10.1016/j.mcn.2022.103780openalex-snapshot

Interleukin-4 activates divergent cell-intrinsic signals to regulate retinal cell proliferation induced by classical growth factors

inferred← citeshttps://doi.org/10.1016/j.molmed.2012.10.009openalex-snapshot

E2F1 apoptosis counterattacked: evil strikes back

inferred← citeshttps://doi.org/10.1016/j.molonc.2012.03.003openalex-snapshot

Oncosuppressive role of p53‐induced miR‐205 in triple negative breast cancer

inferred← citeshttps://doi.org/10.1016/j.molonc.2012.09.006openalex-snapshot

MicroRNA and cancer

inferred← citeshttps://doi.org/10.1016/j.mrfmmm.2015.01.006openalex-snapshot

An epigenomic role of Fe65 in the cellular response to DNA damage

inferred← citeshttps://doi.org/10.1016/j.neo.2017.07.005openalex-snapshot

Effect of HPV E6/E7 siRNA with Chemotherapeutic Agents on the Regulation of TP53/E2F Dynamic Behavior for Cell Fate Decisions

inferred← citeshttps://doi.org/10.1016/j.neulet.2015.10.031openalex-snapshot

Caspase-dependent degradation of MDMx/MDM4 cell cycle regulatory protein in amyloid β-induced neuronal damage

inferred← citeshttps://doi.org/10.1016/j.neuropharm.2012.04.033openalex-snapshot

Vascular endothelial growth factor regulates adult hippocampal cell proliferation through MEK/ERK- and PI3K/Akt-dependent signaling

inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2015.08.017openalex-snapshot

Dynamics of P53 in response to DNA damage: Mathematical modeling and perspective

inferred← citeshttps://doi.org/10.1016/j.pep.2019.05.011openalex-snapshot

Expression and purification of the recombinant full-length retinoblastoma protein and characterisation of its interaction with the oncoprotein HDM2

inferred← citeshttps://doi.org/10.1016/j.resp.2011.11.006openalex-snapshot

Carotid body growth during chronic postnatal hyperoxia

inferred← citeshttps://doi.org/10.1016/j.semcancer.2016.08.008openalex-snapshot

Smyd3-associated regulatory pathways in cancer

inferred← citeshttps://doi.org/10.1016/j.semcdb.2019.07.015openalex-snapshot

Integrated stress response in hepatitis C promotes Nrf2-related chaperone-mediated autophagy: A novel mechanism for host-microbe survival and HCC development in liver cirrhosis

inferred← citeshttps://doi.org/10.1016/j.semradonc.2010.05.007openalex-snapshot

The E2F1/Rb and p53/MDM2 Pathways in DNA Repair and Apoptosis: Understanding the Crosstalk to Develop Novel Strategies for Prostate Cancer Radiotherapy

inferred← citeshttps://doi.org/10.1016/j.tcb.2020.05.002openalex-snapshot

Complex Cartography: Regulation of E2F Transcription Factors by Cyclin F and Ubiquitin

inferred← citeshttps://doi.org/10.1016/j.tplants.2016.04.008openalex-snapshot

The SnRK1 Energy Sensor in Plant Biotic Interactions

inferred← citeshttps://doi.org/10.1016/j.tplants.2019.02.003openalex-snapshot

Revisiting the Female Germline and Its Expanding Toolbox

inferred← citeshttps://doi.org/10.1016/j.tranon.2024.102259openalex-snapshot

Acetylation of E2F1 at K125 facilitates cell apoptosis under serum stress

inferred← citeshttps://doi.org/10.1016/j.xcrm.2025.101966openalex-snapshot

KRASG12D-driven pentose phosphate pathway remodeling imparts a targetable vulnerability synergizing with MRTX1133 for durable remissions in PDAC

inferred← citeshttps://doi.org/10.1016/j.ymeth.2014.02.009openalex-snapshot

Generation of knockout mice using engineered nucleases

inferred← citeshttps://doi.org/10.1038/aps.2014.106openalex-snapshot

Nutlin-3-induced redistribution of chromatin-bound IFI16 in human hepatocellular carcinoma cells in vitro is associated with p53 activation

inferred← citeshttps://doi.org/10.1038/cdd.2009.188openalex-snapshot

E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis

inferred← citeshttps://doi.org/10.1038/cdd.2012.155openalex-snapshot

A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis

inferred← citeshttps://doi.org/10.1038/cdd.2012.89openalex-snapshot

Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis

inferred← citeshttps://doi.org/10.1038/cdd.2013.102openalex-snapshot

Evidence for a novel anti-apoptotic pathway in human keratinocytes involving the aryl hydrocarbon receptor, E2F1, and checkpoint kinase 1

inferred← citeshttps://doi.org/10.1038/cdd.2013.51openalex-snapshot

Interplay between p53 and VEGF: how to prevent the guardian from becoming a villain

inferred← citeshttps://doi.org/10.1038/cdd.2013.6openalex-snapshot

pRb/E2F-1-mediated caspase-dependent induction of Noxa amplifies the apoptotic effects of the Bcl-2/Bcl-xL inhibitor ABT-737

inferred← citeshttps://doi.org/10.1038/cdd.2014.108openalex-snapshot

KMTase Set7/9 is a critical regulator of E2F1 activity upon genotoxic stress

inferred← citeshttps://doi.org/10.1038/cdd.2014.146openalex-snapshot

Regulation of E2F1-induced apoptosis by poly(ADP-ribosyl)ation

inferred← citeshttps://doi.org/10.1038/cddis.2012.142openalex-snapshot

The retinoblastoma protein (Rb) as an anti-apoptotic factor: expression of Rb is required for the anti-apoptotic function of BAG-1 protein in colorectal tumour cells

inferred← citeshttps://doi.org/10.1038/cddis.2013.548openalex-snapshot

Clinical update on cancer: molecular oncology of head and neck cancer

inferred← citeshttps://doi.org/10.1038/leu.2015.71openalex-snapshot

Second generation tyrosine kinase inhibitors prevent disease progression in high-risk (high CIP2A) chronic myeloid leukaemia patients

inferred← citeshttps://doi.org/10.1038/msb.2012.37openalex-snapshot

Inferring transcriptional and microRNA‐mediated regulatory programs in glioblastoma

inferred← citeshttps://doi.org/10.1038/mt.2013.193openalex-snapshot

Transduction of Fetal Mice With a Feline Lentiviral Vector Induces Liver Tumors Which Exhibit an E2F Activation Signature

inferred← citeshttps://doi.org/10.1038/nrc2731openalex-snapshot

20 years studying p53 functions in genetically engineered mice

inferred← citeshttps://doi.org/10.1038/nrd4553openalex-snapshot

Exploiting replicative stress to treat cancer

inferred← citeshttps://doi.org/10.1038/nrm3716openalex-snapshot

The return of the nucleus: transcriptional and epigenetic control of autophagy

inferred← citeshttps://doi.org/10.1038/onc.2010.355openalex-snapshot

Suppression of cell-cycle progression by Jun dimerization protein-2 (JDP2) involves downregulation of cyclin-A2

inferred← citeshttps://doi.org/10.1038/onc.2010.442openalex-snapshot

p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb–Hdm2 interaction and apoptosis

inferred← citeshttps://doi.org/10.1038/onc.2011.277openalex-snapshot

E2F1-dependent oncogenic addiction of melanoma cells to MDM2

inferred← citeshttps://doi.org/10.1038/onc.2011.463openalex-snapshot

Prolyl isomerase Pin1 stabilizes and activates orphan nuclear receptor TR3 to promote mitogenesis

inferred← citeshttps://doi.org/10.1038/onc.2013.316openalex-snapshot

Pleiotropic effect of somatic mutations in the E2F subunit DP-1 gene in human cancer

inferred← citeshttps://doi.org/10.1038/onc.2015.510openalex-snapshot

HTLV-1 bZIP factor protein targets the Rb/E2F-1 pathway to promote proliferation and apoptosis of primary CD4+ T cells

inferred← citeshttps://doi.org/10.1038/onc.2016.242openalex-snapshot

microRNAs with AAGUGC seed motif constitute an integral part of an oncogenic signaling network

inferred← citeshttps://doi.org/10.1038/onc.2016.251openalex-snapshot

Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer

inferred← citeshttps://doi.org/10.1038/onc.2016.502openalex-snapshot

Census and evaluation of p53 target genes

inferred← citeshttps://doi.org/10.1038/s41388-018-0331-zopenalex-snapshot

Artemisitene suppresses tumorigenesis by inducing DNA damage through deregulating c-Myc-topoisomerase pathway

inferred← citeshttps://doi.org/10.1038/s41388-025-03519-5openalex-snapshot

MUC1-C auto-regulatory complex with EBNA1 is responsible for latent Epstein-Barr virus-associated gastric cancer progression

inferred← citeshttps://doi.org/10.1038/s41389-025-00546-5openalex-snapshot

CENPF (+) cancer cells promote malignant progression of early-stage TP53 mutant lung adenocarcinoma

inferred← citeshttps://doi.org/10.1038/s41419-018-1156-yopenalex-snapshot

Comparing effects of CDK inhibition and E2F1/2 ablation on neuronal cell death pathways in vitro and after traumatic brain injury

inferred← citeshttps://doi.org/10.1038/s41420-024-02119-8openalex-snapshot

A testis-specific lncRNA functions as a post-transcriptional regulator of MDM2 and stimulates apoptosis of testicular germ cell tumor cells

inferred← citeshttps://doi.org/10.1038/s41467-023-37340-zopenalex-snapshot

An actin filament branching surveillance system regulates cell cycle progression, cytokinesis and primary ciliogenesis

inferred← citeshttps://doi.org/10.1038/s41467-023-39958-5openalex-snapshot

Multi-omics analysis of human mesenchymal stem cells shows cell aging that alters immunomodulatory activity through the downregulation of PD-L1

inferred← citeshttps://doi.org/10.1038/s41467-024-55660-6openalex-snapshot

YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution

inferred← citeshttps://doi.org/10.1038/s41598-017-10087-6openalex-snapshot

RETRACTED ARTICLE: Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture

inferred← citeshttps://doi.org/10.1038/s41598-018-26860-0openalex-snapshot

Differential requirement for dimerization partner DP between E2F-dependent activation of tumor suppressor and growth-related genes

inferred← citeshttps://doi.org/10.1038/s41598-021-95009-3openalex-snapshot

The role of epigenetic modifications, long-range contacts, enhancers and topologically associating domains in the regulation of glioma grade-specific genes

inferred← citeshttps://doi.org/10.1038/s41598-021-95165-6openalex-snapshot

A CpG island promoter drives the CXXC5 gene expression

inferred← citeshttps://doi.org/10.1038/s41598-021-97265-9openalex-snapshot

Retraction Note: Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture

inferred← citeshttps://doi.org/10.1038/s41598-022-25427-4openalex-snapshot

MDMX elevation by a novel Mdmx–p53 interaction inhibitor mitigates neuronal damage after ischemic stroke

inferred← citeshttps://doi.org/10.1038/s41598-025-91791-6openalex-snapshot

A Nanostring gene expression approach identifies aggressive clinical behavior related genes in dedifferentiated liposarcoma

inferred← citeshttps://doi.org/10.1038/srep03105openalex-snapshot

Requirement for phosphorylation of P53 at Ser312 in suppression of chemical carcinogenesis

inferred← citeshttps://doi.org/10.1039/c3an01409fopenalex-snapshot

Association rule mining of cellular responses induced by metal and metal oxide nanoparticles

inferred← citeshttps://doi.org/10.1039/c5mb00468copenalex-snapshot

A systematic approach to prioritize drug targets using machine learning, a molecular descriptor-based classification model, and high-throughput screening of plant derived molecules: a case study in oral cancer

inferred← citeshttps://doi.org/10.1051/medsci/2012283017openalex-snapshot

La sénescence cellulaire

showing the first 200 of 475 · page through all 475

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.