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Is NF-κB a good target for cancer therapy? Hopes and pitfalls
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Immunodeficiency of alymphoplasia mice (aly/aly)in vivo: structural defect of secondary lymphoid organs and functional B cell defect
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The inhibitors of apoptosis (IAPs) as cancer targets
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The Anti-Death Machinery in IKK/NF-κB Signaling
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A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor
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The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins
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Deregulated NF-κB activity in haematological malignancies
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The alternative NF-κB pathway from biochemistry to biology: Pitfalls and promises for future drug development
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Cytokines and signal transduction
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The malignant clone and the bone-marrow environment
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Smoldering and polarized inflammation in the initiation and promotion of malignant disease
inferredcites →https://doi.org/10.1016/j.ccr.2007.07.003openalex-snapshot
Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma
inferredcites →https://doi.org/10.1016/j.ccr.2007.07.004openalex-snapshot
Frequent Engagement of the Classical and Alternative NF-κB Pathways by Diverse Genetic Abnormalities in Multiple Myeloma
inferredcites →https://doi.org/10.1016/j.ceb.2003.10.005openalex-snapshot
Dying for NF-κB? Control of cell death by transcriptional regulation of the apoptotic machinery
inferredcites →https://doi.org/10.1016/j.cell.2004.07.013openalex-snapshot
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
inferredcites →https://doi.org/10.1016/j.cell.2006.05.030openalex-snapshot
Identification and Validation of Oncogenes in Liver Cancer Using an Integrative Oncogenomic Approach
inferredcites →https://doi.org/10.1016/j.cell.2007.07.009openalex-snapshot
NF-κB Is a Negative Regulator of IL-1β Secretion as Revealed by Genetic and Pharmacological Inhibition of IKKβ
inferredcites →https://doi.org/10.1016/j.cell.2007.10.030openalex-snapshot
IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis
inferredcites →https://doi.org/10.1016/j.cell.2007.10.037openalex-snapshot
IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis
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State of the art therapy in multiple myeloma and future perspectives
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160 years of multiple myeloma: Progress and challenges
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Receptor-Specific Signaling for Both the Alternative and the Canonical NF-κB Activation Pathways by NF-κB-Inducing Kinase
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TRAF2 and TRAF3 Signal Adapters Act Cooperatively to Control the Maturation and Survival Signals Delivered to B Cells by the BAFF Receptor
inferredcites →https://doi.org/10.1016/j.it.2004.03.008openalex-snapshot
The two NF-κB activation pathways and their role in innate and adaptive immunity
inferredcites →https://doi.org/10.1016/j.yexcr.2007.10.021openalex-snapshot
Interactions of myeloma cells with osteoclasts promote tumour expansion and bone degradation through activation of a complex signalling network and upregulation of cathepsin K, matrix metalloproteinases (MMPs) and urokinase plasminogen activator (uPA)
inferredcites →https://doi.org/10.1016/s0092-8674(00)00008-8openalex-snapshot
Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition
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Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins
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The Hallmarks of Cancer
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Missing Pieces in the NF-κB Puzzle
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Signal transduction by tumor necrosis factor and its relatives
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The Lymphotoxin-β Receptor Induces Different Patterns of Gene Expression via Two NF-κB Pathways
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NF-κB-Inducing Kinase Regulates the Processing of NF-κB2 p100
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Global action against cancer
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STI571 (Gleevec™) as a paradigm for cancer therapy
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Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity
inferredcites →https://doi.org/10.1038/385540a0openalex-snapshot
MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1
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Herceptin acts as an anti-angiogenic cocktail
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TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2
inferredcites →https://doi.org/10.1038/8780openalex-snapshot
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-κb-inducing kinase
inferredcites →https://doi.org/10.1038/nature02924openalex-snapshot
NF-κB functions as a tumour promoter in inflammation-associated cancer
inferredcites →https://doi.org/10.1038/nature03491openalex-snapshot
IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation
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Nuclear factor-κB in cancer development and progression
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Characterizing the cancer genome in lung adenocarcinoma
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From signatures to models: understanding cancer using microarrays
inferredcites →https://doi.org/10.1038/ni.1678openalex-snapshot
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling
inferredcites →https://doi.org/10.1038/ni842openalex-snapshot
BAFF-induced NEMO-independent processing of NF-κB2 in maturing B cells
inferredcites →https://doi.org/10.1038/nrc1588openalex-snapshot
Nuclear factor-κB inhibitors as sensitizers to anticancer drugs
inferredcites →https://doi.org/10.1038/nrd1279openalex-snapshot
The IKK NF-κB system: a treasure trove for drug development
inferredcites →https://doi.org/10.1038/nri1703openalex-snapshot
NF-κB: linking inflammation and immunity to cancer development and progression
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Bone marrow endothelial cells increase the invasiveness of human multiple myeloma cells through upregulation of MMP-9: evidence for a role of hepatocyte growth factor
inferredcites →https://doi.org/10.1038/sj.onc.1204623openalex-snapshot
The role of tumor necrosis factor α in the pathophysiology of human multiple myeloma: therapeutic applications
inferredcites →https://doi.org/10.1038/sj.onc.1206315openalex-snapshot
Cell adhesion-mediated drug resistance (CAM-DR) is associated with activation of NF-κB (RelB/p50) in myeloma cells
inferredcites →https://doi.org/10.1038/sj.onc.1209938openalex-snapshot
Current insights into the regulation of programmed cell death by NF-κB
inferredcites →https://doi.org/10.1038/sj.onc.1209942openalex-snapshot
Nuclear factor-κB and inhibitor of κB kinase pathways in oncogenic initiation and progression
inferredcites →https://doi.org/10.1046/j.1365-2141.2001.03102.xopenalex-snapshot
Analysis of expression of nuclear factor κB (NF‐κB) in multiple myeloma: downregulation of NF‐κB induces apoptosis
inferredcites →https://doi.org/10.1053/j.seminoncol.2006.04.013openalex-snapshot
Targeting Loss-of-Function Mutations in Tumor-Suppressor Genes as a Strategy for Development of Cancer Therapeutic Agents
inferredcites →https://doi.org/10.1056/nejm200103153441101openalex-snapshot
Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2
inferredcites →https://doi.org/10.1073/pnas.0805186105openalex-snapshot
NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells
inferredcites →https://doi.org/10.1073/pnas.93.24.13973openalex-snapshot
The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
inferredcites →https://doi.org/10.1074/jbc.m100938200openalex-snapshot
Inhibition of NF-κB Activity by Thalidomide through Suppression of IκB Kinase Activity
inferredcites →https://doi.org/10.1074/jbc.m200360200openalex-snapshot
NF-κB as a Therapeutic Target in Multiple Myeloma
inferredcites →https://doi.org/10.1074/jbc.m300106200openalex-snapshot
RelB/p50 Dimers Are Differentially Regulated by Tumor Necrosis Factor-α and Lymphotoxin-β Receptor Activation
inferredcites →https://doi.org/10.1074/jbc.m403286200openalex-snapshot
Regulation of the NF-κB-inducing Kinase by Tumor Necrosis Factor Receptor-associated Factor 3-induced Degradation
inferredcites →https://doi.org/10.1074/jbc.m610271200openalex-snapshot
Specificity of TRAF3 in Its Negative Regulation of the Noncanonical NF-κB Pathway
inferredcites →https://doi.org/10.1084/jem.20061166openalex-snapshot
Rescue of TRAF3-null mice by p100 NF-κB deficiency
inferredcites →https://doi.org/10.1093/bioinformatics/btl298openalex-snapshot
A supervised approach for identifying discriminating genotype patterns and its application to breast cancer data
inferredcites →https://doi.org/10.1093/bioinformatics/btm033openalex-snapshot
Disease-specific genomic analysis: identifying the signature of pathologic biology
inferredcites →https://doi.org/10.1093/emboj/cdf542openalex-snapshot
CD40 regulates the processing of NF‐κB2 p100 to p52
inferredcites →https://doi.org/10.1097/00062752-200207000-00011openalex-snapshot
Molecular diagnosis of lymphoid malignancies by gene expression profiling
inferredcites →https://doi.org/10.1101/gr.1349003openalex-snapshot
Representational Oligonucleotide Microarray Analysis: A High-Resolution Method to Detect Genome Copy Number Variation
inferredcites →https://doi.org/10.1111/j.1365-2141.2004.04941.xopenalex-snapshot
Phase 2 study of arsenic trioxide in patients with relapsed or refractory multiple myeloma
inferredcites →https://doi.org/10.1111/j.1365-2141.2007.06629.xopenalex-snapshot
Targeting NF‐κB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth
inferredcites →https://doi.org/10.1111/j.1365-2141.2008.07303.xopenalex-snapshot
The relationship between quality of response and clinical benefit for patients treated on the bortezomib arm of the international, randomized, phase 3 APEX trial in relapsed multiple myeloma
inferredcites →https://doi.org/10.1126/science.1058453openalex-snapshot
Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice
inferredcites →https://doi.org/10.1126/science.1098231openalex-snapshot
A Small Molecule Smac Mimic Potentiates TRAIL- and TNFα-Mediated Cell Death
inferredcites →https://doi.org/10.1126/science.1145720openalex-snapshot
The Genomic Landscapes of Human Breast and Colorectal Cancers
inferredcites →https://doi.org/10.1126/science.1157340openalex-snapshot
Essential Cytoplasmic Translocation of a Cytokine Receptor–Assembled Signaling Complex
inferredcites →https://doi.org/10.1126/science.281.5383.1680openalex-snapshot
NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation
inferredcites →https://doi.org/10.1126/science.288.5467.874openalex-snapshot
Ubiquitin Protein Ligase Activity of IAPs and Their Degradation in Proteasomes in Response to Apoptotic Stimuli
inferredcites →https://doi.org/10.1128/mcb.25.8.3348-3356.2005openalex-snapshot
Posttranscriptional Downregulation of c-IAP2 by the Ubiquitin Protein Ligase c-IAP1 In Vivo
inferredcites →https://doi.org/10.1128/mcb.26.2.699-708.2006openalex-snapshot
Inhibitor of Apoptosis Protein cIAP2 Is Essential for Lipopolysaccharide-Induced Macrophage Survival
inferredcites →https://doi.org/10.1146/annurev.immunol.16.1.225openalex-snapshot
NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses
inferredcites →https://doi.org/10.1158/1078-0432.ccr-04-1936openalex-snapshot
Growth Inhibition of Multiple Myeloma Cells by a Novel IκB Kinase Inhibitor
inferredcites →https://doi.org/10.1158/1078-0432.ccr-05-2501openalex-snapshot
MLN120B, a Novel IκB Kinase β Inhibitor, Blocks Multiple Myeloma Cell Growth In vitro and In vivo
inferredcites →https://doi.org/10.1172/jci26322openalex-snapshot
IKK/NF- B signaling: balancing life and death - a new approach to cancer therapy
inferredcites →https://doi.org/10.1172/jci31537openalex-snapshot
A cytokine-mediated link between innate immunity, inflammation, and cancer
inferredcites →https://doi.org/10.1182/blood-2002-05-1320openalex-snapshot
Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor–κB and IκBα kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis
inferredcites →https://doi.org/10.1182/blood-2002-06-1768openalex-snapshot
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications
inferredcites →https://doi.org/10.1182/blood-2003-09-3037openalex-snapshot
Interruption of the NF-κB pathway by Bay 11-7082 promotes UCN-01-mediated mitochondrial dysfunction and apoptosis in human multiple myeloma cells
inferredcites →https://doi.org/10.1182/blood-2006-04-015149openalex-snapshot
Targeting mitochondrial factor Smac/DIABLO as therapy for multiple myeloma (MM)
inferredcites →https://doi.org/10.1182/blood-2006-07-025809openalex-snapshot
Aberrant NF-κB signaling in lymphoma: mechanisms, consequences, and therapeutic implications
inferredcites →https://doi.org/10.1182/blood-2006-07-027458openalex-snapshot
SDX-308, a nonsteroidal anti-inflammatory agent, inhibits NF-κB activity, resulting in strong inhibition of osteoclast formation/activity and multiple myeloma cell growth
inferredcites →https://doi.org/10.1182/blood-2006-09-044974openalex-snapshot
Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib
inferredcites →https://doi.org/10.1182/blood.v87.3.1104.bloodjournal8731104openalex-snapshot
Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa B
inferredcites →https://doi.org/10.1182/blood.v99.11.4079openalex-snapshot
Biologic sequelae of nuclear factor–κB blockade in multiple myeloma: therapeutic applications
inferredcites →https://doi.org/10.1186/bcr1637openalex-snapshot
Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas
inferredcites →https://doi.org/10.3324/haematol.11199openalex-snapshot
Nuclear factor B as a target for new drug development in myeloid malignancies
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Abnormal Immune Function of Hemopoietic Cells from Alymphoplasia ( aly ) Mice, a Natural Strain with Mutant NF-κB-Inducing Kinase
inferredcites →https://doi.org/10.4049/jimmunol.173.4.2245openalex-snapshot
TNF Family Member B Cell-Activating Factor (BAFF) Receptor-Dependent and -Independent Roles for BAFF in B Cell Physiology
inferredcites →https://doi.org/10.4049/jimmunol.173.4.2331openalex-snapshot
B Cell-Activating Factor Belonging to the TNF Family Acts through Separate Receptors to Support B Cell Survival and T Cell-Independent Antibody Formation
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1007/978-1-0716-1669-7_3openalex-snapshot
Immunohistochemical Analysis of Expression, Phosphorylation, and Nuclear Translocation of NF-κB Proteins in Human Tissues
inferred← citeshttps://doi.org/10.1007/978-1-4419-1513-9_6openalex-snapshot
Role of NF-κB Inhibitors in HIV-Related Malignancies
inferred← citeshttps://doi.org/10.1007/978-1-4419-7219-4_5openalex-snapshot
The Angiogenic Switch: Role of Immune Cells
inferred← citeshttps://doi.org/10.1007/978-1-4419-7554-6_6openalex-snapshot
Endothelial Cell Tumor Prevention with Berry Extracts: Clinical Problems, Molecular Mechanisms and Therapeutic Opportunities
inferred← citeshttps://doi.org/10.1007/978-1-4614-0254-1_9openalex-snapshot
Cancer Stem Cells, Models of Study and Implications of Therapy Resistance Mechanisms
inferred← citeshttps://doi.org/10.1007/978-1-4614-4009-3_5openalex-snapshot
Systems Biology of Cell Death in Hepatocytes
inferred← citeshttps://doi.org/10.1007/978-1-4614-4666-8_10openalex-snapshot
Targeting the BAFF/APRIL Cytokine Network in Multiple Myeloma
inferred← citeshttps://doi.org/10.1007/978-1-4614-8039-6_6openalex-snapshot
Nuclear Factors Linking Cancer and Inflammation
inferred← citeshttps://doi.org/10.1007/978-2-8178-0028-8_13openalex-snapshot
Les récepteurs toll-like, l’interleukine 1 et le NFκB
inferred← citeshttps://doi.org/10.1007/978-3-030-16073-9_12openalex-snapshot
Nutrition, Immunity, and Cancer
inferred← citeshttps://doi.org/10.1007/978-3-031-21317-5_5openalex-snapshot
CTNNA1, a New HDGC Gene: Inactivating Mechanisms and Driven Phenotypes
inferred← citeshttps://doi.org/10.1007/978-3-031-62672-2_31openalex-snapshot
Effect of Heavy Metals on Non-muscle Invasive Bladder Cancer and Its Relation to TLR Signaling Pathway
inferred← citeshttps://doi.org/10.1007/978-3-031-63681-3_5openalex-snapshot
The Anticarcinogenic Properties of Brassica Vegetables
inferred← citeshttps://doi.org/10.1007/978-3-319-14340-8_12openalex-snapshot
Toll-Like Receptors, Interleukin 1 and NFκB
inferred← citeshttps://doi.org/10.1007/978-3-319-19144-7_9openalex-snapshot
Sesquiterpenes from Essential Oils with Promising Antitumor Properties
inferred← citeshttps://doi.org/10.1007/978-3-319-21030-8_3openalex-snapshot
Cytokine Networks and Cancer Stem Cells
inferred← citeshttps://doi.org/10.1007/978-3-319-27647-2_10openalex-snapshot
The Unfolded Protein Response as a Therapeutic Target for Head and Neck Squamous Cell Carcinoma
inferred← citeshttps://doi.org/10.1007/978-3-642-12780-9_20openalex-snapshot
New Agents for Patients with Hodgkin Lymphoma
inferred← citeshttps://doi.org/10.1007/978-3-642-38007-5_8openalex-snapshot
Anti-Inflammatory and Anticancer Drugs from Nature
inferred← citeshttps://doi.org/10.1007/978-90-481-9531-2_9openalex-snapshot
Functional Impacts of Signal Integration: Regulation of Inflammation-Related Transcription Factors by Heterotrimeric G Proteins
inferred← citeshttps://doi.org/10.1007/978-94-007-5028-9_10openalex-snapshot
Hodgkin Lymphoma: From Molecular Pathogenesis to Targeted Therapy
inferred← citeshttps://doi.org/10.1007/978-94-007-6211-4_12openalex-snapshot
The Regulation of the JNK Cascade and Programmed Cell Death by NF-κB: Mechanisms and Functions
inferred← citeshttps://doi.org/10.1007/978-94-007-6443-9_1openalex-snapshot
Effect of Dietary Resveratrol in the Treatment of Cancer
inferred← citeshttps://doi.org/10.1007/978-981-10-1498-7_12openalex-snapshot
Noncoding RNAs Regulating NF-κB Signaling
inferred← citeshttps://doi.org/10.1007/978-981-10-6020-5_7openalex-snapshot
Targeting Stemness: Implications for Precision Medicine in Breast Cancer
inferred← citeshttps://doi.org/10.1007/978-981-10-8548-2_15openalex-snapshot
Anticancer Properties of Curcumin and Its Efficacy for Treating Central Nervous System Neoplasms
inferred← citeshttps://doi.org/10.1007/978-981-15-2361-8_18openalex-snapshot
Pharmacological Properties of Essential Oil Constituents and their Mechanisms of Action
inferred← citeshttps://doi.org/10.1007/978-981-97-3014-8_6openalex-snapshot
Role of Grapefruit Seed and Its Secondary Metabolites in Prevention and Treatment of Carcinoma
inferred← citeshttps://doi.org/10.1007/s00005-011-0131-4openalex-snapshot
Targeting NF-κB and HIF-1 Pathways for the Treatment of Cancer: Part I
inferred← citeshttps://doi.org/10.1007/s00005-011-0132-3openalex-snapshot
Targeting NF-κB and HIF-1 Pathways for the Treatment of Cancer: Part II
inferred← citeshttps://doi.org/10.1007/s00005-013-0235-0openalex-snapshot
Mitochondria as Oxidative Signaling Organelles in T-cell Activation: Physiological Role and Pathological Implications
inferred← citeshttps://doi.org/10.1007/s00005-013-0263-9openalex-snapshot
The Role of Glycogen Synthase Kinase 3-β in Immunity and Cell Cycle: Implications in Esophageal Cancer
inferred← citeshttps://doi.org/10.1007/s00018-010-0510-8openalex-snapshot
The multi-targeted kinase inhibitor sorafenib inhibits human cytomegalovirus replication
inferred← citeshttps://doi.org/10.1007/s00018-010-0568-3openalex-snapshot
Viperin mRNA is a novel target for the human RNase MRP/RNase P endoribonuclease
inferred← citeshttps://doi.org/10.1007/s00018-012-1177-0openalex-snapshot
Hsp90 regulation of mitochondrial protein folding: from organelle integrity to cellular homeostasis
inferred← citeshttps://doi.org/10.1007/s00018-013-1545-4openalex-snapshot
NF-κB pathways in hematological malignancies
inferred← citeshttps://doi.org/10.1007/s00018-020-03479-xopenalex-snapshot
Targets for protection and mitigation of radiation injury
inferred← citeshttps://doi.org/10.1007/s00018-023-05098-8openalex-snapshot
Targeting the NF-κB pathway as a potential regulator of immune checkpoints in cancer immunotherapy
inferred← citeshttps://doi.org/10.1007/s00044-010-9409-zopenalex-snapshot
Inhibitory effects on nuclear factor κB of the Vietnamese freshwater cyanobacteria
inferred← citeshttps://doi.org/10.1007/s00109-009-0532-6openalex-snapshot
Benzyl isothiocyanate exhibits anti-inflammatory effects in murine macrophages and in mouse skin
inferred← citeshttps://doi.org/10.1007/s00210-024-03592-9openalex-snapshot
The potential role of targeting the leptin receptor as a treatment for breast cancer in the context of hyperleptinemia: a literature review
inferred← citeshttps://doi.org/10.1007/s00210-026-05611-3openalex-snapshot
Synergistic targeting of NF-κB by cinnamic and p-coumaric acids: computational and DPPH radical scavenging assessment
inferred← citeshttps://doi.org/10.1007/s00262-012-1301-xopenalex-snapshot
EGCG targeting efficacy of NF-κB downstream gene products is dictated by the monocytic/macrophagic differentiation status of promyelocytic leukemia cells
inferred← citeshttps://doi.org/10.1007/s00280-020-04115-yopenalex-snapshot
Chemosensitization by 4-hydroxyphenyl retinamide-induced NF-κB inhibition in acute myeloid leukemia cells
inferred← citeshttps://doi.org/10.1007/s00428-013-1372-xopenalex-snapshot
Nuclear factor-κB activation in primary lymphoma of bone
inferred← citeshttps://doi.org/10.1007/s00432-012-1254-7openalex-snapshot
Guggulsterone enhances antitumor activity of gemcitabine in gallbladder cancer cells through suppression of NF-κB
inferred← citeshttps://doi.org/10.1007/s00438-026-02450-yopenalex-snapshot
FAM72A is associated with lung cancer proliferation and migration via the NF‑κB signaling pathway
inferred← citeshttps://doi.org/10.1007/s00441-011-1264-9openalex-snapshot
How the concentration of insulin affects the development of preantral follicles in goats
inferred← citeshttps://doi.org/10.1007/s10238-018-0504-7openalex-snapshot
Synergistic effect of TRAIL and irradiation in elimination of glioblastoma stem-like cells
inferred← citeshttps://doi.org/10.1007/s10534-014-9804-xopenalex-snapshot
The role of selenoprotein W in inflammatory injury in chicken immune tissues and cultured splenic lymphocyte
inferred← citeshttps://doi.org/10.1007/s10549-017-4149-0openalex-snapshot
Opposing roles of Nfkb2 gene products p100 and p52 in the regulation of breast cancer stem cells
inferred← citeshttps://doi.org/10.1007/s10555-010-9262-zopenalex-snapshot
Stem cell marker olfactomedin 4: critical appraisal of its characteristics and role in tumorigenesis
inferred← citeshttps://doi.org/10.1007/s10555-024-10226-2openalex-snapshot
TRIM-endous functional network of tripartite motif 29 (TRIM29) in cancer progression and beyond
inferred← citeshttps://doi.org/10.1007/s10637-013-0016-yopenalex-snapshot
Ketoprofen-loaded polymeric nanocapsules selectively inhibit cancer cell growth in vitro and in preclinical model of glioblastoma multiforme
inferred← citeshttps://doi.org/10.1007/s10637-014-0185-3openalex-snapshot
The marine natural product microsclerodermin A is a novel inhibitor of the nuclear factor kappa B and induces apoptosis in pancreatic cancer cells
inferred← citeshttps://doi.org/10.1007/s10637-021-01137-yopenalex-snapshot
Network pharmacology of triptolide in cancer cells: implications for transcription factor binding
inferred← citeshttps://doi.org/10.1007/s10753-011-9346-0openalex-snapshot
Parthenolide, a Sesquiterpene Lactone, Expresses Multiple Anti-cancer and Anti-inflammatory Activities
inferred← citeshttps://doi.org/10.1007/s10753-021-01458-3openalex-snapshot
MicroRNA: Could It Play a Role in Bovine Endometritis?
inferred← citeshttps://doi.org/10.1007/s10911-019-09431-5openalex-snapshot
BRCA1 Attenuates Progesterone Effects on Proliferation and NFκB Activation in Normal Human Mammary Epithelial Cells
inferred← citeshttps://doi.org/10.1007/s10930-017-9696-zopenalex-snapshot
Phosphorylation: Implications in Cancer
inferred← citeshttps://doi.org/10.1007/s11010-013-1639-1openalex-snapshot
Small interfering RNA targeting Rac1 sensitizes colon cancer to dihydroartemisinin-induced cell cycle arrest and inhibited cell migration by suppressing NFκB activity
inferred← citeshttps://doi.org/10.1007/s11010-017-3234-3openalex-snapshot
Lipopolysaccharide stimulates endogenous β-glucuronidase via PKC/NF-κB/c-myc signaling cascade: a possible factor in hepatolithiasis formation
inferred← citeshttps://doi.org/10.1007/s11060-010-0516-yopenalex-snapshot
Sensitization to TRAIL-induced apoptosis in human neuroblastoma SK-N-AS cells by NF-κB inhibitors is dependent on reactive oxygen species (ROS)
inferred← citeshttps://doi.org/10.1007/s11060-014-1474-6openalex-snapshot
The proteomic response in glioblastoma in young patients
inferred← citeshttps://doi.org/10.1007/s11064-012-0827-9openalex-snapshot
Therapeutic Efficacy of Silibinin on Human Neuroblastoma Cells: Akt and NF-κB Expressions May Play an Important Role in Silibinin-Induced Response
inferred← citeshttps://doi.org/10.1007/s11064-017-2355-0openalex-snapshot
Proteasome Stress Triggers Death of SH-SY5Y and T98G Cells via Different Cellular Mechanisms
inferred← citeshttps://doi.org/10.1007/s11101-013-9287-3openalex-snapshot
Suppression of essential pro-inflammatory signaling pathways by natural agents for the therapy of Multiple Myeloma
inferred← citeshttps://doi.org/10.1007/s11418-021-01526-wopenalex-snapshot
Inhibition of cell-intrinsic NF-κB activity and metastatic abilities of breast cancer by aloe-emodin and emodic-acid isolated from Asphodelus microcarpus
inferred← citeshttps://doi.org/10.1007/s11864-023-01101-3openalex-snapshot
Recurrent/Metastatic Nasopharyngeal Carcinoma Treatment from Present to Future: Where Are We and Where Are We Heading?
inferred← citeshttps://doi.org/10.1007/s11864-025-01295-8openalex-snapshot
Impact of Genetic Polymorphisms on Treatment Outcomes of Proteasome Inhibitors and Immunomodulatory Drugs in Multiple Myeloma
inferred← citeshttps://doi.org/10.1007/s11906-017-0740-3openalex-snapshot
Androgens and Hypertension in Men and Women: a Unifying View
inferred← citeshttps://doi.org/10.1007/s12013-014-0352-3openalex-snapshot
Efficacy of Arsenic Trioxide in the Treatment of Malignant Pleural Effusion Caused by Pleural Metastasis of Lung Cancer
inferred← citeshttps://doi.org/10.1007/s12013-024-01440-4openalex-snapshot
Chemical Implications of apo-8, 6’ Carotendial versus Intact Lycopene on Mechanism of Enhanced Cell-cell Communication and Apoptosis Induction in Breast Cancer Cells
inferred← citeshttps://doi.org/10.1007/s12032-009-9294-9openalex-snapshot
Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-κB-mediated induction of XIAP, cIAP2, BCL-XL and survivin
inferred← citeshttps://doi.org/10.1007/s12032-023-02275-4openalex-snapshot
A therapeutical insight into the correlation between circRNAs and signaling pathways involved in cancer pathogenesis
inferred← citeshttps://doi.org/10.1007/s12032-026-03308-4openalex-snapshot
Decoy oligonucleotide technology in cancer therapy: molecular mechanisms, challenges, and translational potential
inferred← citeshttps://doi.org/10.1007/s12035-015-9320-1openalex-snapshot
Withania somnifera Suppresses Tumor Growth of Intracranial Allograft of Glioma Cells
inferred← citeshttps://doi.org/10.1007/s12253-012-9519-7openalex-snapshot
The Plasmodium Circumsporozoite Protein, a Novel NF-κB Inhibitor, Suppresses the Growth of SW480
inferred← citeshttps://doi.org/10.1007/s12257-024-00088-4openalex-snapshot
Dual-drug-loaded MSCs-derived exosomal vesicles inhibit endometrial cancer cell proliferation by promoting apoptosis through the migration and invasion of Rac1/NF-κB/MMP2 signalling pathway
inferred← citeshttps://doi.org/10.1007/s12263-009-0133-6openalex-snapshot
Diet-induced obesity increases NF-κB signaling in reporter mice
inferred← citeshttps://doi.org/10.1007/s12272-013-0319-8openalex-snapshot
Co-culture with NK-92MI cells enhanced the anti-cancer effect of bee venom on NSCLC cells by inactivation of NF-κB
inferred← citeshttps://doi.org/10.1007/s12272-021-01317-7openalex-snapshot
LncRNA AIRN influences the proliferation and apoptosis of hepatocellular carcinoma cells by regulating STAT1 ubiquitination
inferred← citeshttps://doi.org/10.1007/s12282-021-01224-1openalex-snapshot
A transposon screen identifies enhancement of NF-κB pathway as a mechanism of resistance to eribulin
inferred← citeshttps://doi.org/10.1007/s12672-026-04947-9openalex-snapshot
Multidimensional single-cell analysis of the molecular characteristics and functional pathways of Regulatory T cells in the microenvironment of HR+ breast cancer
inferred← citeshttps://doi.org/10.1007/s13105-015-0440-xopenalex-snapshot
KPNβ1 promotes palmitate-induced insulin resistance via NF-κB signaling in hepatocytes
inferred← citeshttps://doi.org/10.1007/s13193-015-0451-7openalex-snapshot
Cancer Stem Cells: Formidable Allies of Cancer
inferred← citeshttps://doi.org/10.1007/s13273-013-0031-2openalex-snapshot
The extract of Tamarindus indica L. suppresses IKKβ activity and NF-κB-dependent lymphoblastoid cell line survival
inferred← citeshttps://doi.org/10.1007/s13277-014-1659-9openalex-snapshot
Gene set enrichment analysis of the NF-κB/Snail/YY1/RKIP circuitry in multiple myeloma
inferred← citeshttps://doi.org/10.1007/s13277-015-3575-zopenalex-snapshot
MST-312 induces G2/M cell cycle arrest and apoptosis in APL cells through inhibition of telomerase activity and suppression of NF-κB pathway
inferred← citeshttps://doi.org/10.1007/s13277-016-4973-6openalex-snapshot
In vitro evaluation of antitumoral efficacy of catalase in combination with traditional chemotherapeutic drugs against human lung adenocarcinoma cells
inferred← citeshttps://doi.org/10.1007/s13277-016-5205-9openalex-snapshot
miR-101 sensitizes K562 cell line to imatinib through Jak2 downregulation and inhibition of NF-κB target genes
inferred← citeshttps://doi.org/10.1007/s13277-016-5288-3openalex-snapshot
PTK7 regulates radioresistance through nuclear factor-kappa B in esophageal squamous cell carcinoma
inferred← citeshttps://doi.org/10.1007/s13402-018-0376-6openalex-snapshot
Organ-specific metastasis of breast cancer: molecular and cellular mechanisms underlying lung metastasis
inferred← citeshttps://doi.org/10.1007/s42770-020-00391-1openalex-snapshot
The frequency of high-risk human papillomavirus types, HPV16 lineages, and their relationship with p16INK4a and NF-κB expression in head and neck squamous cell carcinomas in Southwestern Iran
inferred← citeshttps://doi.org/10.1016/b978-0-08-100596-5.22724-8openalex-snapshot
The Influence of Nutrients and Bioactive Compounds on the Expression of microRNAs Related to Inflammation and Chronic Diseases
inferred← citeshttps://doi.org/10.1016/b978-0-12-378630-2.00335-2openalex-snapshot
Nuclear Factor Kappa B
inferred← citeshttps://doi.org/10.1016/b978-0-12-407190-2.00016-2openalex-snapshot
FOXM1 (Forkhead box M1) in Tumorigenesis
inferred← citeshttps://doi.org/10.1016/b978-0-12-811022-5.00014-0openalex-snapshot
Noncoding RNA Alterations in Cancer Molecular Pathways
inferred← citeshttps://doi.org/10.1016/b978-0-12-817661-0.00006-8openalex-snapshot
Curcumin and Genistein Enhance the Sensitivity of Pancreatic Cancer to Chemotherapy
inferred← citeshttps://doi.org/10.1016/b978-0-12-819178-1.00017-4openalex-snapshot
MicroRNAs and inflammation biomarkers in obesity
inferred← citeshttps://doi.org/10.1016/b978-0-12-819612-0.00019-5openalex-snapshot
Therapeutic targeting of SNAIL, RKIP, and YY1 in tumor metastasis and drug resistance
inferred← citeshttps://doi.org/10.1016/b978-0-12-819937-4.00009-1openalex-snapshot
Rac1b: An emerging therapeutic target for chemoresistance in colorectal cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-823482-2.00017-0openalex-snapshot
Glucosinolates and their bioactive metabolites as functional compounds modulating inflammation
inferred← citeshttps://doi.org/10.1016/b978-0-323-42863-7.00013-xopenalex-snapshot
Nanotechnology for cancer therapy
inferred← citeshttps://doi.org/10.1016/b978-0-323-99883-3.00015-9openalex-snapshot
Cancer and apoptosis
inferred← citeshttps://doi.org/10.1016/b978-0-443-13209-4.00018-0openalex-snapshot
Cancer stem cells—Challenges for cancer therapies
inferred← citeshttps://doi.org/10.1016/b978-0-443-13342-8.00009-0openalex-snapshot
Therapeutic potential for coxib-nitric oxide releasing hybrids in cancer treatment
inferred← citeshttps://doi.org/10.1016/b978-0-443-13821-8.00008-1openalex-snapshot
Antigenotoxic and antitumor properties of polyphenols
inferred← citeshttps://doi.org/10.1016/b978-1-4377-0974-2.00033-6openalex-snapshot
Leukocytic Disorders
inferred← citeshttps://doi.org/10.1016/bs.acc.2015.12.003openalex-snapshot
Apoptosis Markers in Breast Cancer Therapy
inferred← citeshttps://doi.org/10.1016/bs.alkal.2024.03.001openalex-snapshot
Structural variety and pharmacological potential of naphthylisoquinoline alkaloids
inferred← citeshttps://doi.org/10.1016/bs.apcsb.2016.11.006openalex-snapshot
Targeting IKK and NF-κB for Therapy
inferred← citeshttps://doi.org/10.1016/bs.enz.2015.06.002openalex-snapshot
Mechanism of the Anticancer Effect of Lycopene (Tetraterpenoids)
inferred← citeshttps://doi.org/10.1016/bs.ircmb.2020.10.006openalex-snapshot
The many-sided contributions of NF-κB to T-cell biology in health and disease
inferred← citeshttps://doi.org/10.1016/j.ab.2010.02.020openalex-snapshot
Surface plasmon resonance analysis of nuclear factor-κB protein interactions with the sesquiterpene lactone helenalin
inferred← citeshttps://doi.org/10.1016/j.actbio.2016.06.031openalex-snapshot
Functionalized cell nucleus-penetrating peptide combined with doxorubicin for synergistic treatment of glioma
inferred← citeshttps://doi.org/10.1016/j.acuro.2010.08.002openalex-snapshot
Antígeno prostático específico y NF-kB en patología prostática: relación con la malignidad
inferred← citeshttps://doi.org/10.1016/j.addr.2015.10.019openalex-snapshot
“Combo” nanomedicine: Co-delivery of multi-modal therapeutics for efficient, targeted, and safe cancer therapy
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2024.741116openalex-snapshot
ChCaspase-1 cleaves ChGasdermin-E, inducing pyroptosis, and participates in the bacterial defence of the oyster Crassostrea hongkongensis
inferred← citeshttps://doi.org/10.1016/j.bbagen.2012.10.024openalex-snapshot
Effects of celastrol on human cervical cancer cells as revealed by ion-trap gas chromatography–mass spectrometry based metabolic profiling
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2011.08.007openalex-snapshot
TRAP-1, the mitochondrial Hsp90
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2017.06.021openalex-snapshot
NAP1L1 regulates NF-κB signaling pathway acting on anti-apoptotic Mcl-1 gene expression
inferred← citeshttps://doi.org/10.1016/j.bbcan.2010.01.002openalex-snapshot
Targeting transcription factor NF-κB to overcome chemoresistance and radioresistance in cancer therapy
inferred← citeshttps://doi.org/10.1016/j.bbcan.2021.188578openalex-snapshot
The interaction of SET and protein phosphatase 2A as target for cancer therapy
inferred← citeshttps://doi.org/10.1016/j.bbrc.2011.07.090openalex-snapshot
Protein kinase Cη activates NF-κB in response to camptothecin-induced DNA damage
inferred← citeshttps://doi.org/10.1016/j.bbrc.2011.10.050openalex-snapshot
Novel regulatory role for Kaposi’s sarcoma-associated herpesvirus-encoded vFLIP in chemosensitization to bleomycin
inferred← citeshttps://doi.org/10.1016/j.bbrc.2014.09.022openalex-snapshot
Nuclear factor-κB is a common upstream signal for growth differentiation factor-5 expression in brown adipocytes exposed to pro-inflammatory cytokines and palmitate
inferred← citeshttps://doi.org/10.1016/j.bbrc.2014.10.023openalex-snapshot
RBP-J-interacting and tubulin-associated protein induces apoptosis and cell cycle arrest in human hepatocellular carcinoma by activating the p53–Fbxw7 pathway
inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.08.052openalex-snapshot
ABCB5 promotes melanoma metastasis through enhancing NF-κB p65 protein stability
inferred← citeshttps://doi.org/10.1016/j.bbrep.2026.102548openalex-snapshot
NF-κB signaling pathway mediates the anti-tumor effect of Ginsenoside Rg1 in glioblastoma
inferred← citeshttps://doi.org/10.1016/j.bcp.2009.05.009openalex-snapshot
The inhibition of TNF-α-induced NF-κB activation by marine natural products
inferred← citeshttps://doi.org/10.1016/j.bcp.2009.09.027openalex-snapshot
Heteronemin, a spongean sesterterpene, inhibits TNFα-induced NF-κB activation through proteasome inhibition and induces apoptotic cell death
inferred← citeshttps://doi.org/10.1016/j.bcp.2010.10.014openalex-snapshot
NFκB inhibitors induce cell death in glioblastomas
inferred← citeshttps://doi.org/10.1016/j.bcp.2011.05.029openalex-snapshot
Helenalin bypasses Bcl-2-mediated cell death resistance by inhibiting NF-κB and promoting reactive oxygen species generation
inferred← citeshttps://doi.org/10.1016/j.bcp.2011.07.083openalex-snapshot
Direct inhibition of NF-κB activation by peptide targeting the NOA ubiquitin binding domain of NEMO
inferred← citeshttps://doi.org/10.1016/j.bcp.2015.12.016openalex-snapshot
The protein kinase IKKepsilon contributes to tumour growth and tumour pain in a melanoma model
inferred← citeshttps://doi.org/10.1016/j.biocel.2009.06.010openalex-snapshot
Apoptosis signaling in cancer stem cells
inferred← citeshttps://doi.org/10.1016/j.biocel.2012.08.002openalex-snapshot
Cancer: NF-κB regulates energy metabolism
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2010.08.080openalex-snapshot
Post-formulation peptide drug loading of nanostructures for metered control of NF-κB signaling
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2015.09.037openalex-snapshot
Nanomedicine-mediated cancer stem cell therapy
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2021.120961openalex-snapshot
Chitin-derived polymer deacetylation regulates mitochondrial reactive oxygen species dependent cGAS-STING and NLRP3 inflammasome activation
inferred← citeshttps://doi.org/10.1016/j.bioorg.2018.09.006openalex-snapshot
The azatryptophan-based fluorescent platform for in vitro rapid screening of inhibitors disrupting IKKβ-NEMO interaction
inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.104973openalex-snapshot
Design, synthesis and in vivo anticancer activity of novel parthenolide and micheliolide derivatives as NF-κB and STAT3 inhibitors
inferred← citeshttps://doi.org/10.1016/j.biopha.2016.12.055openalex-snapshot
AMD3100 combined with triptolide inhibit proliferation, invasion and metastasis and induce apoptosis of human U2OS osteosarcoma cells
inferred← citeshttps://doi.org/10.1016/j.biopha.2017.02.038openalex-snapshot
Ginsenoside Rg3 promotes cytotoxicity of Paclitaxel through inhibiting NF-κB signaling and regulating Bax/Bcl-2 expression on triple-negative breast cancer
inferred← citeshttps://doi.org/10.1016/j.biopha.2017.08.127openalex-snapshot
Triptolide suppresses growth and hormone secretion in murine pituitary corticotroph tumor cells via NF-kappaB signaling pathway
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