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Kynurenines in the CNS: recent advances and new questions

https://doi.org/10.1038/nrd3793
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inferredcites →https://doi.org/10.1002/ardp.201000016openalex-snapshot
Synthesis and Pharmacological Evaluation of Some 4‐Oxo‐quinoline‐2‐carboxylic Acid Derivatives as Anti‐inflammatory and Analgesic Agents
inferredcites →https://doi.org/10.1002/biot.200600001openalex-snapshot
Inhibitors of human indoleamine 2,3‐dioxygenase identified with a target‐based screen in yeast
inferredcites →https://doi.org/10.1002/chin.199435294openalex-snapshot
ChemInform Abstract: Evaluation of Substituted β‐Carbolines as Noncompetitive Indolamine 2,3‐Dioxygenase Inhibitors.
inferredcites →https://doi.org/10.1002/chin.199820156openalex-snapshot
ChemInform Abstract: Synthesis and Biochemical Evaluation of N‐(4‐Phenylthiazol‐2‐yl)benzenesulfonamides as High‐Affinity Inhibitors of Kynurenine 3‐Hydroxylase.
inferredcites →https://doi.org/10.1006/exnr.1999.7284openalex-snapshot
In Situ Produced 7-Chlorokynurenate Provides Protection against Quinolinate- and Malonate-Induced Neurotoxicity in the Rat Striatum
inferredcites →https://doi.org/10.1006/exnr.2002.7973openalex-snapshot
Effect of 3-Nitropropionic Acid on Kynurenine Aminotransferase in the Rat Brain
inferredcites →https://doi.org/10.1006/phrs.1998.0362openalex-snapshot
THE ANALGESIC EFFECTS OF TRYPTOPHAN AND ITS METABOLITES IN THE RAT
inferredcites →https://doi.org/10.1007/978-1-4615-0135-0_71openalex-snapshot
Modulation of the Kynurine Pathway of Tryptophan Metabolism in Search for Neuroprotective Agents. Focus on Kynurenine-3-Hydroxylase
inferredcites →https://doi.org/10.1007/978-1-4615-4709-9_19openalex-snapshot
Degradation of Tryptophan in Neurodegenerative Disorders
inferredcites →https://doi.org/10.1007/bf00173584openalex-snapshot
Excitatory amino acid receptors in rat locus coeruleus
inferredcites →https://doi.org/10.1007/bf00869773openalex-snapshot
Interleukin-2, soluble interleukin-2-receptor, neopterin,l-tryptophan and ?2-microglobulin levels in CSF and serum of patients with relapsing-remitting or chronic-progressive multiple sclerosis
inferredcites →https://doi.org/10.1007/s00109-007-0229-7openalex-snapshot
IDO expression in the brain: a double-edged sword
inferredcites →https://doi.org/10.1007/s00210-011-0605-2openalex-snapshot
Different inhibitory effects of kynurenic acid and a novel kynurenic acid analogue on tumour necrosis factor-α (TNF-α) production by mononuclear cells, HMGB1 production by monocytes and HNP1-3 secretion by neutrophils
inferredcites →https://doi.org/10.1007/s00262-008-0513-6openalex-snapshot
IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism
inferredcites →https://doi.org/10.1007/s00702-006-0545-zopenalex-snapshot
Kynurenine in combination with probenecid mitigates the stimulation-induced increase of c-fos immunoreactivity of the rat caudal trigeminal nucleus in an experimental migraine model
inferredcites →https://doi.org/10.1007/s00702-007-0667-yopenalex-snapshot
Astrocytic activation in relation to inflammatory markers during clinical exacerbation of relapsing-remitting multiple sclerosis
inferredcites →https://doi.org/10.1007/s00702-008-0052-5openalex-snapshot
The Janus-face kynurenic acid
inferredcites →https://doi.org/10.1007/s00702-009-0346-2openalex-snapshot
A novel kynurenic acid analogue: a comparison with kynurenic acid. An in vitro electrophysiological study
inferredcites →https://doi.org/10.1007/s00702-010-0573-6openalex-snapshot
Neuroprotective effects of a novel kynurenic acid analogue in a transgenic mouse model of Huntington’s disease
inferredcites →https://doi.org/10.1007/s00702-011-0665-yopenalex-snapshot
Kynurenines and headache
inferredcites →https://doi.org/10.1007/s00702-011-0681-yopenalex-snapshot
The kynurenine system and immunoregulation
inferredcites →https://doi.org/10.1007/s00702-011-0755-xopenalex-snapshot
A novel kynurenic acid analog (SZR104) inhibits pentylenetetrazole-induced epileptiform seizures. An electrophysiological study
inferredcites →https://doi.org/10.1007/s007020050029openalex-snapshot
Tryptophan degradation and immune activation in Alzheimer's disease
inferredcites →https://doi.org/10.1007/s007020050149openalex-snapshot
Kynurenine metabolism in Alzheimer's disease
inferredcites →https://doi.org/10.1007/s007020200014openalex-snapshot
Increased neopterin production and tryptophan degradation in advanced Parkinson's disease.
inferredcites →https://doi.org/10.1007/s11010-007-9635-yopenalex-snapshot
Differential immunosuppressive effect of indoleamine 2,3-dioxygenase (IDO) on primary human CD4+ and CD8+ T cells
inferredcites →https://doi.org/10.1007/s12640-009-9129-7openalex-snapshot
The Kynurenine Pathway and Inflammation in Amyotrophic Lateral Sclerosis
inferredcites →https://doi.org/10.1016/0003-9861(84)90579-4openalex-snapshot
Inhibition of indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase by β-carboline and indole derivatives
inferredcites →https://doi.org/10.1016/0006-2952(91)90279-eopenalex-snapshot
4-Halo-3-hydroxyanthranilic acids: Potent competitive inhibitors of 3-hydroxy-anthranilic acid oxygenase in vitro
inferredcites →https://doi.org/10.1016/0006-8993(89)90901-3openalex-snapshot
Regulation of striatal serotonin release by the lateral habenula-dorsal raphe pathway in the rat as demonstrated by in vivo microdialysis: role of excitatory amino acids and GABA
inferredcites →https://doi.org/10.1016/0006-8993(91)90065-4openalex-snapshot
Evidence for glutamic acid as a possible neurotransmitter between the mesencephalic nucleus cuneiformis and the medullary nucleus raphe magnus in the lightly anesthetized rat
inferredcites →https://doi.org/10.1016/0022-510x(92)90191-mopenalex-snapshot
Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex
inferredcites →https://doi.org/10.1016/0022-510x(94)00280-2openalex-snapshot
Dysfunction of brain kynurenic acid metabolism in Huntington's disease: focus on kynurenine aminotransferases
inferredcites →https://doi.org/10.1016/0028-3908(95)00145-xopenalex-snapshot
Systemic dl-Kynurenine and probenecid pretreatment attenuates quinolinic acid-induced neurotoxicity in rats
inferredcites →https://doi.org/10.1016/0304-3940(92)90749-wopenalex-snapshot
Increased brain concentrations of a neurotoxin, 3-hydroxykynurenine, in Huntington's disease
inferredcites →https://doi.org/10.1016/0304-3940(93)90796-nopenalex-snapshot
MK-801, an receptor antagonist, blocks quinolinic acid-induced lipid peroxidation in rat corpus striatum
inferredcites →https://doi.org/10.1016/0304-3940(95)11324-popenalex-snapshot
Frontal cortex indoleamine-2,3-dioxygenase activity is increased in HIV-1-associated dementia
inferredcites →https://doi.org/10.1016/0306-4522(94)90227-5openalex-snapshot
Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities
inferredcites →https://doi.org/10.1016/0387-7604(95)00065-jopenalex-snapshot
Studies on cerebrospinal fluid kynurenic acid concentrations in epileptic children
inferredcites →https://doi.org/10.1016/0887-8994(91)90023-eopenalex-snapshot
Studies on CSF tryptophan metabolism in infantile spasms
inferredcites →https://doi.org/10.1016/0887-8994(91)90028-jopenalex-snapshot
Changes in CSF neurotransmitters in infantile spasms
inferredcites →https://doi.org/10.1016/0887-8994(94)90060-4openalex-snapshot
Kynurenic acid is decreased in cerebrospinal fluid of patients with infantile spasms
inferredcites →https://doi.org/10.1016/0960-894x(95)00255-ropenalex-snapshot
Synthesis and activity of enantiopure (S) (m-nitrobenzoyl) alanine, potent kynurenine-3-hydroxylase inhibitor
inferredcites →https://doi.org/10.1016/j.bbapap.2011.07.023openalex-snapshot
Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors
inferredcites →https://doi.org/10.1016/j.bbr.2010.02.041openalex-snapshot
Protective effect of systemic l-kynurenine and probenecid administration on behavioural and morphological alterations induced by toxic soluble amyloid beta (25–35) in rat hippocampus
inferredcites →https://doi.org/10.1016/j.bbrc.2010.06.091openalex-snapshot
Expression of functional GPR35 in human iNKT cells
inferredcites →https://doi.org/10.1016/j.bmc.2010.12.032openalex-snapshot
Indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors
inferredcites →https://doi.org/10.1016/j.bmc.2011.10.068openalex-snapshot
Novel indoleamine 2,3-dioxygenase-1 inhibitors from a multistep in silico screen
inferredcites →https://doi.org/10.1016/j.bmcl.2006.10.033openalex-snapshot
Kynurenic acid amides as novel NR2B selective NMDA receptor antagonists
inferredcites →https://doi.org/10.1016/j.bmcl.2010.07.025openalex-snapshot
S-Benzylisothiourea derivatives as small-molecule inhibitors of indoleamine-2,3-dioxygenase
inferredcites →https://doi.org/10.1016/j.brainres.2004.01.004openalex-snapshot
Cortical spreading depression augments kynurenate levels and reduces malonate toxicity in the rat cortex
inferredcites →https://doi.org/10.1016/j.brainres.2005.04.081openalex-snapshot
Antiallodynic effects of NMDA glycineB antagonists in neuropathic pain: Possible peripheral mechanisms
inferredcites →https://doi.org/10.1016/j.brainresbull.2007.12.001openalex-snapshot
The pentylenetetrazole-induced activity in the hippocampus can be inhibited by the conversion of l-kynurenine to kynurenic acid: An in vitro study
inferredcites →https://doi.org/10.1016/j.cell.2011.05.020openalex-snapshot
Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration
inferredcites →https://doi.org/10.1016/j.cub.2011.04.028openalex-snapshot
The Kynurenine Pathway Modulates Neurodegeneration in a Drosophila Model of Huntington's Disease
inferredcites →https://doi.org/10.1016/j.ddstr.2006.09.005openalex-snapshot
Anti-inflammatory strategies for the treatment of multiple sclerosis – tryptophan catabolites may hold the key
inferredcites →https://doi.org/10.1016/j.ejcb.2008.03.003openalex-snapshot
Kynurenic acid attenuates MPP+-induced dopaminergic neuronal cell death via a Bax-mediated mitochondrial pathway
inferredcites →https://doi.org/10.1016/j.ejmech.2010.05.057openalex-snapshot
Identification of potent virtual leads to design novel indoleamine 2,3-dioxygenase inhibitors: Pharmacophore modeling and molecular docking studies
inferredcites →https://doi.org/10.1016/j.ejphar.2005.02.043openalex-snapshot
Systemically administered glucosamine-kynurenic acid, but not pure kynurenic acid, is effective in decreasing the evoked activity in area CA1 of the rat hippocampus
inferredcites →https://doi.org/10.1016/j.ejphar.2006.05.015openalex-snapshot
Enhancement of brain kynurenic acid production by anticonvulsants—Novel mechanism of antiepileptic activity?
inferredcites →https://doi.org/10.1016/j.ejphar.2007.02.029openalex-snapshot
Neuroprotective effect of L-kynurenine sulfate administered before focal cerebral ischemia in mice and global cerebral ischemia in gerbils
inferredcites →https://doi.org/10.1016/j.ejphar.2011.05.069openalex-snapshot
Neuroprotection with a new kynurenic acid analog in the four-vessel occlusion model of ischemia
inferredcites →https://doi.org/10.1016/j.expneurol.2003.12.001openalex-snapshot
Kynurenine aminotransferase in the supratentorial dura mater of the rat: effect of stimulation of the trigeminal ganglion
inferredcites →https://doi.org/10.1016/j.expneurol.2005.07.004openalex-snapshot
Endogenous kynurenate controls the vulnerability of striatal neurons to quinolinate: Implications for Huntington's disease
inferredcites →https://doi.org/10.1016/j.expneurol.2008.10.018openalex-snapshot
Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2007.12.003openalex-snapshot
Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage
inferredcites →https://doi.org/10.1016/j.gene.2007.04.010openalex-snapshot
Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice
inferredcites →https://doi.org/10.1016/j.lfs.2008.02.014openalex-snapshot
Neuroprotection achieved in the ischaemic rat cortex with l-kynurenine sulphate
inferredcites →https://doi.org/10.1016/j.nbd.2004.07.006openalex-snapshot
Neostriatal and cortical quinolinate levels are increased in early grade Huntington's disease
inferredcites →https://doi.org/10.1016/j.nbd.2006.02.011openalex-snapshot
Elevated brain 3-hydroxykynurenine and quinolinate levels in Huntington disease mice
inferredcites →https://doi.org/10.1016/j.nbd.2008.07.013openalex-snapshot
Kynurenine diminishes the ischemia-induced histological and electrophysiological deficits in the rat hippocampus
inferredcites →https://doi.org/10.1016/j.neuint.2006.08.012openalex-snapshot
Decreased serum and red blood cell kynurenic acid levels in Alzheimer's disease
inferredcites →https://doi.org/10.1016/j.neulet.2006.03.051openalex-snapshot
Kynurenic acid has a dual action on AMPA receptor responses
inferredcites →https://doi.org/10.1016/j.neulet.2007.03.007openalex-snapshot
Prevention of electrical stimulation-induced increase of c-fos immunoreaction in the caudal trigeminal nucleus by kynurenine combined with probenecid
inferredcites →https://doi.org/10.1016/j.neures.2008.04.009openalex-snapshot
The kynurenate analog SZR-72 prevents the nitroglycerol-induced increase of c-fos immunoreactivity in the rat caudal trigeminal nucleus: Comparative studies of the effects of SZR-72 and kynurenic acid
inferredcites →https://doi.org/10.1016/j.neuropharm.2004.06.007openalex-snapshot
Kynurenine administered together with probenecid markedly inhibits pentylenetetrazol-induced seizures. An electrophysiological and behavioural study
inferredcites →https://doi.org/10.1016/j.neuropharm.2009.06.033openalex-snapshot
l-kynurenine combined with probenecid and the novel synthetic kynurenic acid derivative attenuate nitroglycerin-induced nNOS in the rat caudal trigeminal nucleus
inferredcites →https://doi.org/10.1016/j.neuroscience.2004.04.043openalex-snapshot
Decreased expression of kynurenine aminotransferase-I (KAT-I) in the substantia nigra of mice after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment
inferredcites →https://doi.org/10.1016/j.ntt.2010.10.002openalex-snapshot
Protective effect of l-kynurenine and probenecid on 6-hydroxydopamine-induced striatal toxicity in rats: Implications of modulating kynurenate as a protective strategy
inferredcites →https://doi.org/10.1016/j.ntt.2011.07.002openalex-snapshot
On the antioxidant properties of kynurenic acid: Free radical scavenging activity and inhibition of oxidative stress
inferredcites →https://doi.org/10.1016/j.nurt.2007.01.008openalex-snapshot
Familial Hemiplegic Migraine
inferredcites →https://doi.org/10.1016/j.steroids.2004.05.019openalex-snapshot
Antigen-specific T cell functions are suppressed over the estrogen-dendritic cell-indoleamine 2,3-dioxygenase axis
inferredcites →https://doi.org/10.1016/s0006-2952(03)00464-7openalex-snapshot
Inhibition of indoleamine 2,3-dioxygenase activity in IFN-γ stimulated astroglioma cells decreases intracellular NAD levels
inferredcites →https://doi.org/10.1016/s0006-8993(00)01962-4openalex-snapshot
Systemically administered d-glucose conjugates of 7-chlorokynurenic acid are centrally available and exert anticonvulsant activity in rodents
inferredcites →https://doi.org/10.1016/s0006-8993(01)02017-0openalex-snapshot
Oligodendrocyte killing by quinolinic acid in vitro
inferredcites →https://doi.org/10.1016/s0014-2999(00)00024-8openalex-snapshot
Systemic administration of 4-chlorokynurenine prevents quinolinate neurotoxicity in the rat hippocampus
inferredcites →https://doi.org/10.1016/s0014-2999(96)00613-9openalex-snapshot
(R,S)-3,4-dichlorobenzoylalanine (FCE 28833A) causes a large and persistent increase in brain kynurenic acid levels in rats
inferredcites →https://doi.org/10.1016/s0140-6736(08)60918-6openalex-snapshot
Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
inferredcites →https://doi.org/10.1016/s0165-5728(02)00176-5openalex-snapshot
Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitis
inferredcites →https://doi.org/10.1016/s0165-6147(00)01451-6openalex-snapshot
Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection
inferredcites →https://doi.org/10.1016/s0223-5234(99)00220-2openalex-snapshot
Synthesis and QSAR of substituted 3-hydroxyanthranilic acid derivatives as inhibitors of 3-hydroxyanthranilic acid dioxygenase (3-HAO)
inferredcites →https://doi.org/10.1016/s0278-5846(98)00070-0openalex-snapshot
Comparison of intrastriatal injections of quinolinic acid and 3-nitropropionic acid for use in animal models of Huntington's disease
inferredcites →https://doi.org/10.1016/s0304-3940(00)00956-3openalex-snapshot
Early kynurenergic impairment in Huntington's Disease and in a transgenic animal model
inferredcites →https://doi.org/10.1016/s0304-3940(02)00710-3openalex-snapshot
Decreased level of kynurenic acid in cerebrospinal fluid of relapsing-onset multiple sclerosis patients
inferredcites →https://doi.org/10.1016/s0304-3940(02)00735-8openalex-snapshot
1-Methyl-4-phenylpyridinium and 3-nitropropionic acid diminish cortical synthesis of kynurenic acid via interference with kynurenine aminotransferases in rats
inferredcites →https://doi.org/10.1016/s0306-4522(00)00504-2openalex-snapshot
Kynurenine 3-mono-oxygenase activity and neurotoxic kynurenine metabolites increase in the spinal cord of rats with experimental allergic encephalomyelitis
inferredcites →https://doi.org/10.1016/s0306-4522(96)00655-0openalex-snapshot
Protection against quinolinic acid-mediated excitotoxicity in nigrostriatal dopaminergic neurons by endogenous kynurenic acid
inferredcites →https://doi.org/10.1016/s0896-6273(02)00615-3openalex-snapshot
Increased Sensitivity to N-Methyl-D-Aspartate Receptor-Mediated Excitotoxicity in a Mouse Model of Huntington's Disease
inferredcites →https://doi.org/10.1016/s0960-894x(01)00758-2openalex-snapshot
2-Amino-4-[3′-hydroxyphenyl]-4-hydroxybutanoic acid; A potent inhibitor of rat and recombinant human kynureninase
inferredcites →https://doi.org/10.1016/s0960-894x(97)10209-8openalex-snapshot
S-Aryl cysteine S,S-dioxides as inhibitors of mammalian kynureninase
inferredcites →https://doi.org/10.1016/s0968-0896(00)00318-7openalex-snapshot
A comparative study on the inhibition of human and bacterial kynureninase by novel bicyclic kynurenine analogues
inferredcites →https://doi.org/10.1017/s0029665111003193openalex-snapshot
Vitamin D, invariant natural killer T-cells and experimental autoimmune disease
inferredcites →https://doi.org/10.1021/bi901546eopenalex-snapshot
The Selenazal Drug Ebselen Potently Inhibits Indoleamine 2,3-Dioxygenase by Targeting Enzyme Cysteine Residues
inferredcites →https://doi.org/10.1021/ja00057a007openalex-snapshot
S-Aryl-L-cysteine S,S-dioxides: design, synthesis, and evaluation of a new class of inhibitors of kynureninase
inferredcites →https://doi.org/10.1021/jm00031a015openalex-snapshot
Modulation of the Kynurenine Pathway in Search for New Neuroprotective Agents.Synthesis and Preliminary Evaluation of (m-Nitrobenzoyl)alanine, a Potent Inhibitor of Kynurenine-3-hydroxylase
inferredcites →https://doi.org/10.1021/jm0508888openalex-snapshot
Structure−Activity Study of Brassinin Derivatives as Indoleamine 2,3-Dioxygenase Inhibitors
inferredcites →https://doi.org/10.1021/jm300260vopenalex-snapshot
Rational Design of 4-Aryl-1,2,3-Triazoles for Indoleamine 2,3-Dioxygenase 1 Inhibition
inferredcites →https://doi.org/10.1021/jm7014155openalex-snapshot
Indoleamine 2,3-Dioxygenase Is the Anticancer Target for a Novel Series of Potent Naphthoquinone-Based Inhibitors
inferredcites →https://doi.org/10.1021/jm800143hopenalex-snapshot
Synthesis of Indoleamine 2,3-Dioxygenase Inhibitory Analogues of the Sponge Alkaloid Exiguamine A
inferredcites →https://doi.org/10.1021/jm800512zopenalex-snapshot
Structure Based Development of Phenylimidazole-Derived Inhibitors of Indoleamine 2,3-Dioxygenase
inferredcites →https://doi.org/10.1021/jm8010806openalex-snapshot
Crystal Structure of theHomo sapiensKynureninase-3-Hydroxyhippuric Acid Inhibitor Complex: Insights into the Molecular Basis Of Kynureninase Substrate Specificity
inferredcites →https://doi.org/10.1021/jm900518fopenalex-snapshot
Discovery of Potent Competitive Inhibitors of Indoleamine 2,3-Dioxygenase with in Vivo Pharmacodynamic Activity and Efficacy in a Mouse Melanoma Model
inferredcites →https://doi.org/10.1021/jm9014718openalex-snapshot
Rational Design of Indoleamine 2,3-Dioxygenase Inhibitors
inferredcites →https://doi.org/10.1021/jm970467topenalex-snapshot
Synthesis and Biochemical Evaluation ofN-(4-Phenylthiazol-2-yl)benzenesulfonamides as High-Affinity Inhibitors of Kynurenine 3-Hydroxylase
inferredcites →https://doi.org/10.1021/np060111xopenalex-snapshot
Indoleamine 2,3-Dioxygenase Inhibitors from the Northeastern Pacific Marine Hydroid Garveia annulata
inferredcites →https://doi.org/10.1021/ol900972jopenalex-snapshot
Plectosphaeroic Acids A, B, and C, Indoleamine 2,3-Dioxygenase Inhibitors Produced in Culture by a Marine Isolate of the Fungus Plectosphaerella cucumerina
inferredcites →https://doi.org/10.1023/a:1022482604276openalex-snapshot
Blood-Brain Barrier Carrier-Mediated Transport and Brain Metabolism of Amino Acids
inferredcites →https://doi.org/10.1034/j.1600-0404.2003.00076.xopenalex-snapshot
Endogenous protectant kynurenic acid in amyotrophic lateral sclerosis
inferredcites →https://doi.org/10.1038/321168a0openalex-snapshot
Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid
inferredcites →https://doi.org/10.1038/ejhg.2011.48openalex-snapshot
Meta-analysis of genome-wide association for migraine in six population-based European cohorts
inferredcites →https://doi.org/10.1038/jcbfm.1992.57openalex-snapshot
Neuroprotective Effects of L-Kynurenine on Hypoxia—Ischemia and NMDA Lesions in Neonatal Rats
inferredcites →https://doi.org/10.1038/nature10491openalex-snapshot
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
inferredcites →https://doi.org/10.1038/nchembio.107openalex-snapshot
Biomimetic synthesis of the IDO inhibitors exiguamine A and B
inferredcites →https://doi.org/10.1038/ng.652openalex-snapshot
Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1
inferredcites →https://doi.org/10.1038/ng.856openalex-snapshot
Genome-wide association study reveals three susceptibility loci for common migraine in the general population
inferredcites →https://doi.org/10.1038/ng1542openalex-snapshot
A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease
inferredcites →https://doi.org/10.1038/ni.2077openalex-snapshot
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells
inferredcites →https://doi.org/10.1038/nm.2056openalex-snapshot
Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin
inferredcites →https://doi.org/10.1038/nm.2092openalex-snapshot
Kynurenine is an endothelium-derived relaxing factor produced during inflammation
inferredcites →https://doi.org/10.1038/nm1196openalex-snapshot
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
inferredcites →https://doi.org/10.1038/nn835openalex-snapshot
Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
inferredcites →https://doi.org/10.1038/nrn3257openalex-snapshot
Kynurenines in the mammalian brain: when physiology meets pathology
inferredcites →https://doi.org/10.1038/sj.bjp.0701834openalex-snapshot
Modulation of striatal quinolinate neurotoxicity by elevation of endogenous brain kynurenic acid
inferredcites →https://doi.org/10.1038/sj.bjp.0704842openalex-snapshot
Nitric oxide synthase inhibitors can antagonize neurogenic and calcitonin gene‐related peptide induced dilation of dural meningeal vessels
inferredcites →https://doi.org/10.1038/sj.cdd.4401073openalex-snapshot
T cell apoptosis by tryptophan catabolism
inferredcites →https://doi.org/10.1038/sj.onc.1210939openalex-snapshot
A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2,3-dioxygenase
inferredcites →https://doi.org/10.1039/b208910fopenalex-snapshot
Differential effects of bromination on substrates and inhibitors of kynureninase from Pseudomonas fluorescens
inferredcites →https://doi.org/10.1042/bj2910011openalex-snapshot
4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-γ-stimulated monocytes (THP-1 cells)
inferredcites →https://doi.org/10.1046/j.0022-3042.2002.00805.xopenalex-snapshot
Direct evidence that release‐stimulating α7* nicotinic cholinergic receptors are localized on human and rat brain glutamatergic axon terminals
inferredcites →https://doi.org/10.1046/j.1365-2567.2002.01526.xopenalex-snapshot
Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division
inferredcites →https://doi.org/10.1046/j.1468-2982.1995.015002132.xopenalex-snapshot
Platelet and Plasma Levels of Glutamate and Glutamine in Migraine With and Without Aura
inferredcites →https://doi.org/10.1046/j.1471-4159.1995.64031192.xopenalex-snapshot
Neurotoxin Quinolinic Acid Is Selectively Elevated in Spinal Cords of Rats with Experimental Allergic Encephalomyelitis
inferredcites →https://doi.org/10.1046/j.1471-4159.1996.66030996.xopenalex-snapshot
Regulation of the Kynurenine Metabolic Pathway by Interferon‐γ in Murine Cloned Macrophages and Microglial Cells
inferredcites →https://doi.org/10.1046/j.1471-4159.1999.0721125.xopenalex-snapshot
Effects of Mitochondria and O‐Methoxybenzoylalanine on 3‐Hydroxyanthranilic Acid Dioxygenase Activity and Quinolinic Acid Synthesis
inferredcites →https://doi.org/10.1046/j.1471-4159.1999.0730750.xopenalex-snapshot
The Non‐NMDA Glutamate Receptor Antagonists 6‐Cyano‐7‐Nitroquinoxaline‐2,3‐dione and 2,3‐Dihydroxy‐6‐Nitro‐7‐Sulfamoylbenzo(f)quinoxaline, but Not NMDA Antagonists, Block the Intrastriatal Neurotoxic Effect of MPP+
inferredcites →https://doi.org/10.1056/nejmoa1014656openalex-snapshot
Randomized Trial of Oral Teriflunomide for Relapsing Multiple Sclerosis
inferredcites →https://doi.org/10.1056/nejmoa1104318openalex-snapshot
Placebo-Controlled Trial of Oral Laquinimod for Multiple Sclerosis
inferredcites →https://doi.org/10.1073/pnas.85.11.4079openalex-snapshot
3-Hydroxyanthranilate oxygenase activity is increased in the brains of Huntington disease victims.
inferredcites →https://doi.org/10.1073/pnas.85.17.6547openalex-snapshot
7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex.
inferredcites →https://doi.org/10.1074/jbc.m603503200openalex-snapshot
Kynurenic Acid as a Ligand for Orphan G Protein-coupled Receptor GPR35
inferredcites →https://doi.org/10.1084/jem.189.9.1363openalex-snapshot
Inhibition of T Cell Proliferation by Macrophage Tryptophan Catabolism
inferredcites →https://doi.org/10.1084/jem.20020052openalex-snapshot
Inhibition of Allogeneic T Cell Proliferation by Indoleamine 2,3-Dioxygenase–expressing Dendritic Cells
inferredcites →https://doi.org/10.1084/jem.20020121openalex-snapshot
Tryptophan-derived Catabolites Are Responsible for Inhibition of T and Natural Killer Cell Proliferation Induced by Indoleamine 2,3-Dioxygenase
inferredcites →https://doi.org/10.1089/107999001317205231openalex-snapshot
IFN- β 1b Induces Kynurenine Pathway Metabolism in Human Macrophages: Potential Implications for Multiple Sclerosis Treatment
inferredcites →https://doi.org/10.1093/brain/115.5.1249openalex-snapshot
QUINOLINIC ACID AND KYNURENINE PATHWAY METABOLISM IN INFLAMMATORY AND NON-INFLAMMATORY NEUROLOGICAL DISEASE
inferredcites →https://doi.org/10.1093/intimm/dxh003openalex-snapshot
Therapeutic potential of IFN- -modified dendritic cells in acute and chronic experimental allergic encephalomyelitis
inferredcites →https://doi.org/10.1093/intimm/dxh140openalex-snapshot
Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase
inferredcites →https://doi.org/10.1093/intimm/dxh271openalex-snapshot
A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation
inferredcites →https://doi.org/10.1093/oxfordjournals.jbchem.a132635openalex-snapshot
The Mechanism of Kynurenine Hydrolysis Catalyzed by Kynureninase
inferredcites →https://doi.org/10.1096/fj.04-3228fjeopenalex-snapshot
Indolamine 2,3‐dioxygenase is expressed in the CNS and down‐regulates autoimmune inflammation
inferredcites →https://doi.org/10.1097/00001756-200312190-00005openalex-snapshot
Aβ1-42 induces production of quinolinic acid by human macrophages and microglia
inferredcites →https://doi.org/10.1097/00004647-199907000-00007openalex-snapshot
Kynurenine Hydroxylase Inhibitors Reduce Ischemic Brain Damage: Studies with ( m -Nitrobenzoyl)-Alanine (mNBA) and 3,4-Dimethoxy-[-N-4-(Nitrophenyl)Thiazol-2YL]-Benzenesulfonamide (Ro 61-8048) in Models of Focal or Global Brain Ischemia
inferredcites →https://doi.org/10.1097/00005344-200309000-00012openalex-snapshot
Effect of Systemic Administration of L-Kynurenine on Corticocerebral Blood Flow under Normal and Ischemic Conditions of the Brain in Conscious Rabbits
inferredcites →https://doi.org/10.1097/01.mjt.0000208272.42379.aaopenalex-snapshot
Recurrent Headache as the Main Symptom of Acquired Cerebral Toxoplasmosis in Nonhuman Immunodeficiency Virus-infected Subjects With no Lymphadenopathy
inferredcites →https://doi.org/10.1097/maj.0b013e31819f8cacopenalex-snapshot
Is Toxoplasma gondii a Causal Agent in Migraine?
inferredcites →https://doi.org/10.1111/j.1365-2567.2007.02655.xopenalex-snapshot
Innate immunity modulates autoimmunity: type 1 interferon‐β treatment in multiple sclerosis promotes growth and function of regulatory invariant natural killer T cells through dendritic cell maturation
inferredcites →https://doi.org/10.1111/j.1365-2982.2007.00989.xopenalex-snapshot
Kynurenic acid inhibits intestinal hypermotility and xanthine oxidase activity during experimental colon obstruction in dogs
inferredcites →https://doi.org/10.1111/j.1365-2982.2009.01390.xopenalex-snapshot
N-Methyl-d-aspartate receptor antagonism decreases motility and inflammatory activation in the early phase of acute experimental colitis in the rat
inferredcites →https://doi.org/10.1111/j.1365-2990.2005.00655.xopenalex-snapshot
Indoleamine 2,3 dioxygenase and quinolinic acid Immunoreactivity in Alzheimer's disease hippocampus
inferredcites →https://doi.org/10.1111/j.1432-1033.1996.0460u.xopenalex-snapshot
Isolation and Expression of a cDNA Clone Encoding Human Kynureninase
inferredcites →https://doi.org/10.1111/j.1432-1033.2004.04446.xopenalex-snapshot
pH dependence, substrate specificity and inhibition of human kynurenine aminotransferase I
inferredcites →https://doi.org/10.1111/j.1432-2277.2004.00031.xopenalex-snapshot
Studying the immunosuppressive role of indoleamine 2,3-dioxygenase: tryptophan metabolites suppress rat allogeneic T-cell responses in vitro and in vivo
inferredcites →https://doi.org/10.1111/j.1460-9568.2007.05838.xopenalex-snapshot
Altered kynurenine metabolism correlates with infarct volume in stroke
inferredcites →https://doi.org/10.1111/j.1468-1331.2005.01041.xopenalex-snapshot
Interferon‐β affects the tryptophan metabolism in multiple sclerosis patients
inferredcites →https://doi.org/10.1111/j.1468-2982.2004.00750.xopenalex-snapshot
Cerebrospinal Fluid Glutamate Levels in Chronic Migraine
inferredcites →https://doi.org/10.1111/j.1471-4159.1978.tb07815.xopenalex-snapshot
SYNTHESIS AND METABOLISM OF l ‐KYNURENINE IN RAT BRAIN
inferredcites →https://doi.org/10.1111/j.1471-4159.1990.tb03143.xopenalex-snapshot
Kynurenine Pathway Measurements in Huntington's Disease Striatum: Evidence for Reduced Formation of Kynurenic Acid
inferredcites →https://doi.org/10.1111/j.1471-4159.1991.tb03460.xopenalex-snapshot
Blood–Brain Barrier Transport of Kynurenines: Implications for Brain Synthesis and Metabolism
inferredcites →https://doi.org/10.1111/j.1471-4159.1993.tb05836.xopenalex-snapshot
Mechanism of Delayed Increases in Kynurenine Pathway Metabolism in Damaged Brain Regions Following Transient Cerebral Ischemia
inferredcites →https://doi.org/10.1111/j.1471-4159.2005.03070.xopenalex-snapshot
Tryptophan metabolism and oxidative stress in patients with Huntington's disease
inferredcites →https://doi.org/10.1111/j.1471-4159.2010.06675.xopenalex-snapshot
Dysfunctional kynurenine pathway metabolism in the R6/2 mouse model of Huntington’s disease
inferredcites →https://doi.org/10.1111/j.1471-4159.2010.07159.xopenalex-snapshot
Characterization of the kynurenine pathway in NSC‐34 cell line: implications for amyotrophic lateral sclerosis
inferredcites →https://doi.org/10.1111/j.1476-5381.1991.tb12274.xopenalex-snapshot
A comparison of excitotoxic lesions of the basal forebrain by kainate, quinolinate, ibotenate, N‐methyl‐ d ‐aspartate or quisqualate, and the effects on toxicity of 2‐amino‐5‐phosphonovaleric acid and kynurenic acid in the rat
inferredcites →https://doi.org/10.1111/j.1526-4610.2009.01574.xopenalex-snapshot
Kynurenate Derivative Attenuates the Nitroglycerin‐Induced CamKIIα and CGRP Expression Changes
inferredcites →https://doi.org/10.1111/j.1528-1157.1994.tb02428.xopenalex-snapshot
Kynurenine Pathway Metabolites in Cerebrospinal Fluid and Serum in Complex Partial Seizures
inferredcites →https://doi.org/10.1111/j.1600-0404.2005.00442.xopenalex-snapshot
Kynurenine metabolism in multiple sclerosis
inferredcites →https://doi.org/10.1111/j.1742-4658.2012.08485.xopenalex-snapshot
Quinolinic acid, the inescapable neurotoxin
inferredcites →https://doi.org/10.1124/jpet.110.177386openalex-snapshot
Age Dependency of Inhibition of α7 Nicotinic Receptors and Tonically Active N-Methyl-d-aspartate Receptors by Endogenously Produced Kynurenic Acid in the Brain
inferredcites →https://doi.org/10.1126/science.1117634openalex-snapshot
Treatment of Autoimmune Neuroinflammation with a Synthetic Tryptophan Metabolite
inferredcites →https://doi.org/10.1128/iai.70.2.779-786.2002openalex-snapshot
l -Tryptophan- l -Kynurenine Pathway Metabolism Accelerated by Toxoplasma gondii Infection Is Abolished in Gamma Interferon-Gene-Deficient Mice: Cross-Regulation between Inducible Nitric Oxide Synthase and Indoleamine-2,3-Dioxygenase
inferredcites →https://doi.org/10.1136/jnnp.42.7.640openalex-snapshot
Plasma and cerebrospinal fluid tryptophan in multiple sclerosis and degenerative diseases.
inferredcites →https://doi.org/10.1152/jn.00466.2004openalex-snapshot
Protective Effect of Ifenprodil Against Spreading Depression in the Mouse Entorhinal Cortex
inferredcites →https://doi.org/10.1158/0008-5472.can-06-2925openalex-snapshot
Inhibition of Indoleamine 2,3-Dioxygenase in Dendritic Cells by Stereoisomers of 1-Methyl-Tryptophan Correlates with Antitumor Responses
inferredcites →https://doi.org/10.1158/0008-5472.can-07-1872openalex-snapshot
Novel Tryptophan Catabolic Enzyme IDO2 Is the Preferred Biochemical Target of the Antitumor Indoleamine 2,3-Dioxygenase Inhibitory Compound d -1-Methyl-Tryptophan
inferredcites →https://doi.org/10.1158/1535-7163.mct-09-0628openalex-snapshot
Hydroxyamidine Inhibitors of Indoleamine-2,3-dioxygenase Potently Suppress Systemic Tryptophan Catabolism and the Growth of IDO-Expressing Tumors
inferredcites →https://doi.org/10.1177/1352458512436594openalex-snapshot
Long-term follow-up of a phase 2 study of oral teriflunomide in relapsing multiple sclerosis: safety and efficacy results up to 8.5 years
inferredcites →https://doi.org/10.1177/1352458512450354openalex-snapshot
Pre-specified subgroup analyses of a placebo-controlled phase III trial (TEMSO) of oral teriflunomide in relapsing multiple sclerosis
inferredcites →https://doi.org/10.1177/38.12.1701457openalex-snapshot
Relationship of glutamate and aspartate to the periaqueductal gray-raphe magnus projection: analysis using immunocytochemistry and microdialysis.
inferredcites →https://doi.org/10.1182/blood-2005-04-1403openalex-snapshot
Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis
inferredcites →https://doi.org/10.1182/blood-2006-03-006700openalex-snapshot
The tryptophan catabolite l-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function
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A potential role for the gut microbiome in substance use disorders
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Astrocytic and neuronal localization of kynurenine aminotransferase-2 in the adult mouse brain
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The diabetic brain and cognition
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IDO and TDO as a potential therapeutic target in different types of depression
inferred← citeshttps://doi.org/10.1007/s11011-025-01548-3openalex-snapshot
Impact of neuroinflammation on brain glutamate and dopamine signalling in schizophrenia: an update
inferred← citeshttps://doi.org/10.1007/s11033-023-08859-7openalex-snapshot
Kynurenine pathway and its role in neurologic, psychiatric, and inflammatory bowel diseases
inferred← citeshttps://doi.org/10.1007/s11064-020-03144-6openalex-snapshot
Involvement of Indoleamine-2,3-Dioxygenase and Kynurenine Pathway in Experimental Autoimmune Encephalomyelitis in Mice
inferred← citeshttps://doi.org/10.1007/s11064-021-03274-5openalex-snapshot
Epilepsy Associated Depression: An Update on Current Scenario, Suggested Mechanisms, and Opportunities
inferred← citeshttps://doi.org/10.1007/s11095-017-2333-xopenalex-snapshot
Access to the CNS: Biomarker Strategies for Dopaminergic Treatments
inferred← citeshttps://doi.org/10.1007/s11306-017-1288-6openalex-snapshot
Tryptophan metabolism along the kynurenine and serotonin pathways reveals substantial differences in colon and rectal cancer
inferred← citeshttps://doi.org/10.1007/s11306-019-1605-3openalex-snapshot
Urinary metabolomics reveals kynurenine pathway perturbation in newborns with transposition of great arteries after surgical repair
inferred← citeshttps://doi.org/10.1007/s11307-016-1024-zopenalex-snapshot
Improved Radiosynthesis and Biological Evaluations of L- and D-1-[18F]Fluoroethyl-Tryptophan for PET Imaging of IDO-Mediated Kynurenine Pathway of Tryptophan Metabolism
inferred← citeshttps://doi.org/10.1007/s11307-019-01327-4openalex-snapshot
Evaluation of l-1-[18F]Fluoroethyl-Tryptophan for PET Imaging of Cancer
inferred← citeshttps://doi.org/10.1007/s11332-021-00853-5openalex-snapshot
Regular resistance training as a strategy to improve aging-related immune activation
inferred← citeshttps://doi.org/10.1007/s11357-024-01110-6openalex-snapshot
Resistance exercise effects on hippocampus subfield volumes and biomarkers of neuroplasticity and neuroinflammation in older adults with low and high risk of mild cognitive impairment: a randomized controlled trial
inferred← citeshttps://doi.org/10.1007/s11357-025-01636-3openalex-snapshot
Kynurenine pathway dysregulation in cognitive impairment and dementia: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1007/s11481-020-09976-xopenalex-snapshot
Kynurenic Acid Protects Against Reactive Glial-associated Reductions in the Complexity of Primary Cortical Neurons
inferred← citeshttps://doi.org/10.1007/s11739-015-1208-6openalex-snapshot
Fathoming the kynurenine pathway in migraine: why understanding the enzymatic cascades is still critically important
inferred← citeshttps://doi.org/10.1007/s11883-025-01304-zopenalex-snapshot
Recent Advances and Perspectives of Metabolomics-Based Investigations in Coronary Heart Disease
inferred← citeshttps://doi.org/10.1007/s12035-025-05538-5openalex-snapshot
Production, Mechanisms, and Therapeutic Strategies of Tryptophan Metabolites in CNS Diseases
inferred← citeshttps://doi.org/10.1007/s13204-022-02698-xopenalex-snapshot
Advances in nanotechnology versus stem cell therapy for the theranostics of multiple sclerosis disease
inferred← citeshttps://doi.org/10.1007/s13311-018-0616-5openalex-snapshot
Glutamate and Its Receptors as Therapeutic Targets for Migraine
inferred← citeshttps://doi.org/10.1007/s40495-019-00208-2openalex-snapshot
Neuropathology of Kynurenine Pathway of Tryptophan Metabolism
inferred← citeshttps://doi.org/10.1007/s41981-020-00088-4openalex-snapshot
Novel feasibilities for preparation of serum albumin-based core-shell nanoparticles in flow conditions
inferred← citeshttps://doi.org/10.1007/s43440-020-00067-5openalex-snapshot
Antidepressant-like effects of kynurenic acid in a modified forced swim test
inferred← citeshttps://doi.org/10.1016/b978-0-12-800981-9.00025-0openalex-snapshot
Astrocytes as Pharmacological Targets in the Treatment of Schizophrenia
inferred← citeshttps://doi.org/10.1016/b978-0-12-802928-2.00038-2openalex-snapshot
Gut Microbial Metabolism in Health and Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-823453-2.00013-8openalex-snapshot
Gut-brain axis
inferred← citeshttps://doi.org/10.1016/b978-0-323-35214-7.00170-0openalex-snapshot
Pathophysiology of Neonatal Bacterial Meningitis
inferred← citeshttps://doi.org/10.1016/b978-0-323-95650-5.00048-3openalex-snapshot
The kynurenine pathway and role in mental health of post-COVID-19 patients
inferred← citeshttps://doi.org/10.1016/bs.ant.2025.04.001openalex-snapshot
Natural compounds as an alternative to counteract the neurotoxic effects of quinolinic acid
inferred← citeshttps://doi.org/10.1016/bs.apha.2016.01.005openalex-snapshot
Kynurenines and Glutamate
inferred← citeshttps://doi.org/10.1016/j.ab.2019.03.005openalex-snapshot
HPLC method for the assessment of tryptophan metabolism utilizing separate internal standard for each detector
inferred← citeshttps://doi.org/10.1016/j.abb.2020.108702openalex-snapshot
Advantages of brain penetrating inhibitors of kynurenine-3-monooxygenase for treatment of neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.ajcnut.2023.08.003openalex-snapshot
Longitudinal associations of macronutrient and micronutrient intake with plasma kynurenines in colorectal cancer survivors up to 12 months posttreatment
inferred← citeshttps://doi.org/10.1016/j.aninu.2024.03.005openalex-snapshot
Tryptophan metabolism and piglet diarrhea: Where we stand and the challenges ahead
inferred← citeshttps://doi.org/10.1016/j.apradiso.2019.109022openalex-snapshot
Automated production of 1-(2-[18F]fluoroethyl)-l-tryptophan for imaging of tryptophan metabolism
inferred← citeshttps://doi.org/10.1016/j.apsb.2021.01.018openalex-snapshot
AncPhore: A versatile tool for anchor pharmacophore steered drug discovery with applications in discovery of new inhibitors targeting metallo-β-lactamases and indoleamine/tryptophan 2,3-dioxygenases
inferred← citeshttps://doi.org/10.1016/j.autrev.2025.103975openalex-snapshot
The metabolic landscape of connective tissue diseases: Applications and discoveries in metabolomics research
inferred← citeshttps://doi.org/10.1016/j.bbadis.2013.05.002openalex-snapshot
Hyperuricemia influences tryptophan metabolism via inhibition of multidrug resistance protein 4 (MRP4) and breast cancer resistance protein (BCRP)
inferred← citeshttps://doi.org/10.1016/j.bbadis.2022.166509openalex-snapshot
Kynurenine-3-monooxygenase expression is activated in the pancreatic endocrine cells by diabetes and its blockade improves glucose-stimulated insulin secretion
inferred← citeshttps://doi.org/10.1016/j.bbapap.2016.06.014openalex-snapshot
NAD + metabolism: Bioenergetics, signaling and manipulation for therapy
inferred← citeshttps://doi.org/10.1016/j.bbcan.2024.189183openalex-snapshot
Pancreatic ductal adenocarcinoma cells reshape the immune microenvironment: Molecular mechanisms and therapeutic targets
inferred← citeshttps://doi.org/10.1016/j.bbi.2015.01.013openalex-snapshot
Peripheral indoleamine 2,3-dioxygenase 1 is required for comorbid depression-like behavior but does not contribute to neuropathic pain in mice
inferred← citeshttps://doi.org/10.1016/j.bbi.2015.07.016openalex-snapshot
Cerebrospinal fluid kynurenines in multiple sclerosis; relation to disease course and neurocognitive symptoms
inferred← citeshttps://doi.org/10.1016/j.bbi.2015.11.011openalex-snapshot
Microglial dysfunction connects depression and Alzheimer’s disease
inferred← citeshttps://doi.org/10.1016/j.bbi.2015.12.020openalex-snapshot
Mouse chronic social stress increases blood and brain kynurenine pathway activity and fear behaviour: Both effects are reversed by inhibition of indoleamine 2,3-dioxygenase
inferred← citeshttps://doi.org/10.1016/j.bbi.2019.10.005openalex-snapshot
Tryptophan metabolite concentrations in depressed patients before and after electroconvulsive therapy
inferred← citeshttps://doi.org/10.1016/j.bbi.2021.04.020openalex-snapshot
Toward a neuroprotective shift: Eight weeks of high intensity interval training reduces the neurotoxic kynurenine activity concurrently to impulsivity in emotionally impulsive humans – A randomized controlled trial
inferred← citeshttps://doi.org/10.1016/j.bbi.2023.04.015openalex-snapshot
Correlations between kynurenines in plasma and CSF, and their relation to markers of Alzheimer’s disease pathology
inferred← citeshttps://doi.org/10.1016/j.bbih.2026.101175openalex-snapshot
Quinolinic acid as trigger/biomarker of dysosmia/dysgeusia in patients with acute coronavirus disease 2019: A retrospective case-control study
inferred← citeshttps://doi.org/10.1016/j.bbmt.2014.06.008openalex-snapshot
B7 Costimulation and Intracellular Indoleamine 2,3-Dioxygenase Expression in Umbilical Cord Blood and Adult Peripheral Blood
inferred← citeshttps://doi.org/10.1016/j.bbr.2014.05.018openalex-snapshot
The kynurenine pathway contributes to long-term neuropsychological changes in experimental pneumococcal meningitis
inferred← citeshttps://doi.org/10.1016/j.bbr.2014.07.027openalex-snapshot
Serotonin, tryptophan metabolism and the brain-gut-microbiome axis
inferred← citeshttps://doi.org/10.1016/j.bbr.2020.112516openalex-snapshot
Physical exercise rectifies CUMS-induced aberrant regional homogeneity in mice accompanied by the adjustment of skeletal muscle PGC-1a/IDO1 signals and hippocampal function
inferred← citeshttps://doi.org/10.1016/j.bbr.2022.114237openalex-snapshot
The prevalence and the effect of interferon -γ in the comorbidity of rheumatoid arthritis and depression
inferred← citeshttps://doi.org/10.1016/j.bbr.2025.115782openalex-snapshot
The impact of a high-fat diet (HFD) on mouse behavior, neurotransmitters, inflammation, and gut-brain axis metabolism under hypoxic conditions
inferred← citeshttps://doi.org/10.1016/j.bcp.2014.12.009openalex-snapshot
Functional G-protein-coupled receptor 35 is expressed by neurons in the CA1 field of the hippocampus
inferred← citeshttps://doi.org/10.1016/j.bcp.2020.113926openalex-snapshot
PCC0208009, an indirect IDO1 inhibitor, alleviates neuropathic pain and co-morbidities by regulating synaptic plasticity of ACC and amygdala
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116034openalex-snapshot
Mitochondrial targets in hyperammonemia: Addressing urea cycle function to improve drug therapies
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.113040openalex-snapshot
Perivascular brown adipocytes-derived kynurenic acid relaxes blood vessel via endothelium PI3K-Akt-eNOS pathway
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.113257openalex-snapshot
Analog of kynurenic acid decreases tau pathology by modulating astrogliosis in rat model for tauopathy
inferred← citeshttps://doi.org/10.1016/j.bios.2016.11.010openalex-snapshot
Development of screen-printed tryptophan-kynurenine immunosensor for in vitro assay of kynurenine-mediated immunosuppression effect of cancer cells on activated T-cells
inferred← citeshttps://doi.org/10.1016/j.bmcl.2018.07.034openalex-snapshot
Cyclic analogue of S-benzylisothiourea that suppresses kynurenine production without inhibiting indoleamine 2,3-dioxygenase activity
inferred← citeshttps://doi.org/10.1016/j.bmcl.2020.127060openalex-snapshot
Discovery of sulfonamides and 9-oxo-2,8-diazaspiro[5,5]undecane-2-carboxamides as human kynurenine aminotransferase 2 (KAT2) inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2026.130596openalex-snapshot
Design, synthesis and anti-Parkinson's disease bioactivity evaluation of isoquinoline derivatives as potent IDO1/TDO dual inhibitors
inferred← citeshttps://doi.org/10.1016/j.braindev.2025.104359openalex-snapshot
Tryptophan metabolism in children with migraine: The role of kynurenine pathway
inferred← citeshttps://doi.org/10.1016/j.brainres.2018.05.031openalex-snapshot
The cerebral protective effect and mechanism of action of vitamin B6 adjuvant ceftriaxone in experimental pneumococcal meningitis
inferred← citeshttps://doi.org/10.1016/j.brainres.2024.149415openalex-snapshot
Kynurenine pathway dysregulation as a mechanistic link between cognitive impairment and brain damage: Implications for multiple sclerosis
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2015.02.001openalex-snapshot
The inimitable kynurenic acid: The roles of different ionotropic receptors in the action of kynurenic acid at a spinal level
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2018.12.014openalex-snapshot
Investigating KYNA production and kynurenergic manipulation on acute mouse brain slice preparations
inferred← citeshttps://doi.org/10.1016/j.carbpol.2019.115168openalex-snapshot
Evaluation of solubility enhancement, antioxidant activity, and cytotoxicity studies of kynurenic acid loaded cyclodextrin nanosponge
inferred← citeshttps://doi.org/10.1016/j.cellsig.2024.111565openalex-snapshot
Kynureninase induce cuproptosis resistance in gastric cancer progression through downregulating lipotic acid synthetase mediated non-canonical mechanism
inferred← citeshttps://doi.org/10.1016/j.chroma.2016.02.009openalex-snapshot
Stable isotope dilution ultra-high performance liquid chromatography–tandem mass spectrometry quantitative profiling of tryptophan-related neuroactive substances in human serum and cerebrospinal fluid
inferred← citeshttps://doi.org/10.1016/j.chroma.2020.461775openalex-snapshot
Simultaneous determination of 30 neurologically and metabolically important molecules: A sensitive and selective way to measure tyrosine and tryptophan pathway metabolites and other biomarkers in human serum and cerebrospinal fluid
inferred← citeshttps://doi.org/10.1016/j.chroma.2021.462305openalex-snapshot
On-line screening of indoleamine 2,3-dioxygenase 1 inhibitors by partial filling capillary electrophoresis combined with rapid polarity switching
inferred← citeshttps://doi.org/10.1016/j.clineuro.2016.09.006openalex-snapshot
Prion diseases: New considerations
inferred← citeshttps://doi.org/10.1016/j.clnu.2018.04.010openalex-snapshot
Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: A randomized clinical trial
inferred← citeshttps://doi.org/10.1016/j.cmet.2018.01.004openalex-snapshot
Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation
inferred← citeshttps://doi.org/10.1016/j.cmet.2019.09.001openalex-snapshot
NAD+ in Brain Aging and Neurodegenerative Disorders
inferred← citeshttps://doi.org/10.1016/j.cmet.2023.06.004openalex-snapshot
Tryptophan metabolism in health and disease
inferred← citeshttps://doi.org/10.1016/j.cnp.2019.01.004openalex-snapshot
Mechanisms of neurobehavioral abnormalities in multiple sclerosis: Contributions from neural and immune components
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2014.10.046openalex-snapshot
Determination of binding capacity and adsorption enthalpy between Human Glutamate Receptor (GluR1) peptide fragments and kynurenic acid by surface plasmon resonance experiments
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2015.04.044openalex-snapshot
Determination of binding capacity and adsorption enthalpy between Human Glutamate Receptor (GluR1) peptide fragments and kynurenic acid by surface plasmon resonance experiments. Part 2: Interaction of GluR1270–300 with KYNA
inferred← citeshttps://doi.org/10.1016/j.coph.2016.06.008openalex-snapshot
Psychological side effects of immune therapies: symptoms and pathomechanism
inferred← citeshttps://doi.org/10.1016/j.drudis.2015.11.001openalex-snapshot
Kynurenine-3-monooxygenase: a review of structure, mechanism, and inhibitors
inferred← citeshttps://doi.org/10.1016/j.ebiom.2021.103734openalex-snapshot
Kynurenine induces T cell fat catabolism and has limited suppressive effects in vivo
inferred← citeshttps://doi.org/10.1016/j.ejcb.2024.151418openalex-snapshot
Neuroimmune modulation by tryptophan derivatives in neurological and inflammatory disorders
inferred← citeshttps://doi.org/10.1016/j.ejmech.2014.06.078openalex-snapshot
Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors
inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.08.013openalex-snapshot
Design, synthesis and biological evaluation of novel naphthoquinone derivatives as IDO1 inhibitors
inferred← citeshttps://doi.org/10.1016/j.ejps.2016.02.012openalex-snapshot
Targeting of the kynurenic acid across the blood–brain barrier by core-shell nanoparticles
inferred← citeshttps://doi.org/10.1016/j.ejps.2026.107674openalex-snapshot
An integrated experimental–computational platform for evaluating blood–brain barrier permeability of novel kynurenic acid derivatives
inferred← citeshttps://doi.org/10.1016/j.exger.2019.110793openalex-snapshot
Clinical insights into the kynurenine pathway in age-related diseases
inferred← citeshttps://doi.org/10.1016/j.expneurol.2013.08.007openalex-snapshot
The absence of indoleamine 2,3-dioxygenase expression protects against NMDA receptor-mediated excitotoxicity in mouse brain
inferred← citeshttps://doi.org/10.1016/j.fct.2018.04.042openalex-snapshot
Putrescine as indicator of manganese neurotoxicity: Dose-response study in human SH-SY5Y cells
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2014.06.003openalex-snapshot
Scavenging of reactive oxygen species by tryptophan metabolites helps Pseudomonas aeruginosa escape neutrophil killing
inferred← citeshttps://doi.org/10.1016/j.gene.2020.144434openalex-snapshot
Organ-differential responses to ethanol and kynurenic acid, a component of alcoholic beverages in gene transcription
inferred← citeshttps://doi.org/10.1016/j.heliyon.2021.e06124openalex-snapshot
Cuprizone markedly decreases kynurenic acid levels in the rodent brain tissue and plasma
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.131995openalex-snapshot
Structural characterization and improves cognitive disorder in ageing mice of a glucomannan from Dendrobium huoshanense
inferred← citeshttps://doi.org/10.1016/j.ijcard.2015.03.413openalex-snapshot
Kynurenines as predictors of acute coronary events in the Hordaland Health Study
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113651openalex-snapshot
The tryptophan metabolite kynurenic acid ameliorates septic colonic injury through activation of the PPARγ signaling pathway
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.115769openalex-snapshot
Tryptophan metabolism alteration is associated with rapidly progressive interstitial lung disease of anti-MDA5+ dermatomyositis
inferred← citeshttps://doi.org/10.1016/j.isci.2019.07.019openalex-snapshot
Bright Green Biofluorescence in Sharks Derives from Bromo-Kynurenine Metabolism
inferred← citeshttps://doi.org/10.1016/j.jaci.2015.09.055openalex-snapshot
The tryptophan metabolism enzyme L-kynureninase is a novel inflammatory factor in psoriasis and other inflammatory diseases
inferred← citeshttps://doi.org/10.1016/j.jalz.2017.04.009openalex-snapshot
Association of amine biomarkers with incident dementia and Alzheimer's disease in the Framingham Study
inferred← citeshttps://doi.org/10.1016/j.jchromb.2017.04.010openalex-snapshot
Simultaneous determination of tryptophan and 8 metabolites in human plasma by liquid chromatography/tandem mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.jchromb.2019.02.021openalex-snapshot
LC-MS/MS-based quantification of tryptophan metabolites and neurotransmitters in the serum and brain of mice
inferred← citeshttps://doi.org/10.1016/j.jchromb.2026.124993openalex-snapshot
Elucidating the molecular basis of Salvia miltiorrhiza Salvianolic acids and Tanshinones in treating ischemic stroke: A multidimensional strategy of in vivo Chemomics, targeted network pharmacology, and metabolomics
inferred← citeshttps://doi.org/10.1016/j.jgr.2024.12.002openalex-snapshot
Ginsenoside Rg1 exerts antidepressant effect by regulating hepatic kynurenine metabolism through promoting the interaction between HNF4α and PGC1α
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.136965openalex-snapshot
Neurotoxic effects of citronellol induced by the conversion of kynurenine to 3-hydroxykynurenine
inferred← citeshttps://doi.org/10.1016/j.jneuroim.2018.03.007openalex-snapshot
HIV, prospective memory, and cerebrospinal fluid concentrations of quinolinic acid and phosphorylated Tau
inferred← citeshttps://doi.org/10.1016/j.jns.2017.02.053openalex-snapshot
Kynurenic acid and its analogue can alter the opioid receptor G-protein signaling after acute treatment via NMDA receptor in rat cortex and striatum
inferred← citeshttps://doi.org/10.1016/j.jns.2023.120819openalex-snapshot
The role of the kynurenine pathway in cognitive functioning after stroke: A prospective clinical study
inferred← citeshttps://doi.org/10.1016/j.jns.2025.123522openalex-snapshot
The kynurenine pathway and markers of neurodegeneration and cerebral small vessel disease: The Maastricht Study
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2023.109282openalex-snapshot
DSS-induced acute colitis causes dysregulated tryptophan metabolism in brain: an involvement of gut microbiota
inferred← citeshttps://doi.org/10.1016/j.jocn.2013.08.020openalex-snapshot
Serum indoleamine 2,3-dioxygenase and kynurenine aminotransferase enzyme activity in patients with ischemic stroke
inferred← citeshttps://doi.org/10.1016/j.jpba.2015.08.026openalex-snapshot
Quantitative analysis of phenylalanine, tyrosine, tryptophan and kynurenine in rat model for tauopathies by ultra-high performance liquid chromatography with fluorescence and mass spectrometry detection
inferred← citeshttps://doi.org/10.1016/j.jpba.2019.113018openalex-snapshot
Development, validation and application of LC–MS/MS method for quantification of amino acids, kynurenine and serotonin in human plasma
inferred← citeshttps://doi.org/10.1016/j.jpba.2020.113246openalex-snapshot
A validated UHPLC-MS method for tryptophan metabolites: Application in the diagnosis of multiple sclerosis
inferred← citeshttps://doi.org/10.1016/j.jvs.2017.09.029openalex-snapshot
Plasma microbiome-modulated indole- and phenyl-derived metabolites associate with advanced atherosclerosis and postoperative outcomes
inferred← citeshttps://doi.org/10.1016/j.mad.2021.111567openalex-snapshot
Preclinical and clinical evidence of NAD+ precursors in health, disease, and ageing
inferred← citeshttps://doi.org/10.1016/j.mad.2023.111890openalex-snapshot
Relation of the kynurenine pathway with normal age: A systematic review
inferred← citeshttps://doi.org/10.1016/j.molmed.2021.07.006openalex-snapshot
The kynurenine pathway in chronic diseases: a compensatory mechanism or a driving force?
inferred← citeshttps://doi.org/10.1016/j.msard.2022.103667openalex-snapshot
Association between microglial activation and serum kynurenine pathway metabolites in multiple sclerosis patients
inferred← citeshttps://doi.org/10.1016/j.mvr.2017.05.006openalex-snapshot
Systemic administration of l -kynurenine sulfate induces cerebral hypoperfusion transients in adult C57Bl/6 mice
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2023.105065openalex-snapshot
Myokines may target accelerated cognitive aging in people with spinal cord injury: A systematic and topical review
inferred← citeshttps://doi.org/10.1016/j.neuint.2020.104752openalex-snapshot
Long-term systemic administration of kynurenic acid brain region specifically elevates the abundance of functional CB1 receptors in rats
inferred← citeshttps://doi.org/10.1016/j.neuint.2020.104771openalex-snapshot
Peripheral and cerebral abnormalities of the tryptophan metabolism in the depression-like rats induced by chronic unpredicted mild stress
inferred← citeshttps://doi.org/10.1016/j.neuint.2020.104920openalex-snapshot
Species-specific neuronal localization of kynurenine aminotransferase-2 in the mouse cerebellum
inferred← citeshttps://doi.org/10.1016/j.neulet.2013.08.028openalex-snapshot
Paradox effects of kynurenines on LTP induction in the Wistar rat. An in vivo study
inferred← citeshttps://doi.org/10.1016/j.neulet.2025.138220openalex-snapshot
Age-dependent changes in NMDA-induced excitotoxicity and neuromodulatory effects of kynurenic acid and its analogue in mouse brain slices
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2013.02.006openalex-snapshot
The neuroprotector kynurenic acid increases neuronal cell survival through neprilysin induction
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2015.12.004openalex-snapshot
Stress-related regulation of the kynurenine pathway: Relevance to neuropsychiatric and degenerative disorders
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