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Genetic insights into the morphogenesis of inner ear hair cells
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What this work says Outgoing claims: the papers this work cites, builds on, or argues with.
inferred cites → https://doi.org/10.1002/cm.10092 openalex-snapshot Transient expression of the t‐isoform of plastins/fimbrin in the stereocilia of developing auditory hair cells
inferred cites → https://doi.org/10.1002/cne.10944 openalex-snapshot Correlation of expression of the actin filament‐bundling protein espin with stereociliary bundle formation in the developing inner ear
inferred cites → https://doi.org/10.1002/cne.903250208 openalex-snapshot Distribution of the 275 kD hair cell antigen and cell surface specialisations on auditory and vestibular hair bundles in the chicken inner ear
inferred cites → https://doi.org/10.1038/78140 openalex-snapshot A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse
inferred cites → https://doi.org/10.1038/79171 openalex-snapshot A defect in harmonin, a PDZ domain-containing protein expressed in the inner ear sensory hair cells, underlies Usher syndrome type 1C
inferred cites → https://doi.org/10.1038/79178 openalex-snapshot A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the Usher type 1C gene
inferred cites → https://doi.org/10.1038/83660 openalex-snapshot Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D
inferred cites → https://doi.org/10.1038/83667 openalex-snapshot Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D
inferred cites → https://doi.org/10.1038/83837 openalex-snapshot The mouse Ames waltzer hearing-loss mutant is caused by mutation of Pcdh15, a novel protocadherin gene
inferred cites → https://doi.org/10.1038/ng1208 openalex-snapshot Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31
inferred cites → https://doi.org/10.1038/ng1295-369 openalex-snapshot The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells
inferred cites → https://doi.org/10.1038/nn1089 openalex-snapshot Fast adaptation of mechanoelectrical transducer channels in mammalian cochlear hair cells
inferred cites → https://doi.org/10.1073/pnas.2334417100 openalex-snapshot Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundle
inferred cites → https://doi.org/10.1083/jcb.112.4.641 openalex-snapshot Three different actin filament assemblies occur in every hair cell: each contains a specific actin crosslinking protein.
inferred cites → https://doi.org/10.1083/jcb.143.1.121 openalex-snapshot Why Are Two Different Cross-linkers Necessary for Actin Bundle Formation In Vivo and What Does Each Cross-link Contribute?
inferred cites → https://doi.org/10.1083/jcb.95.1.249 openalex-snapshot Interactions between actin filaments and between actin filaments and membranes in quick-frozen and deeply etched hair cells of the chick ear.
inferred cites → https://doi.org/10.1083/jcb.96.3.822 openalex-snapshot Actin filaments, stereocilia, and hair cells of the bird cochlea. II. Packing of actin filaments in the stereocilia and in the cuticular plate and what happens to the organization when the stereocilia are bent.
inferred cites → https://doi.org/10.1086/316954 openalex-snapshot Usher Syndrome 1D and Nonsyndromic Autosomal Recessive Deafness DFNB12 Are Caused by Allelic Mutations of the Novel Cadherin-Like Gene CDH23
inferred cites → https://doi.org/10.1086/323156 openalex-snapshot MYO6, the Human Homologue of the Gene Responsible for Deafness in Snell’s Waltzer Mice, Is Mutated in Autosomal Dominant Nonsyndromic Hearing Loss
inferred cites → https://doi.org/10.1086/379286 openalex-snapshot Mutations in the γ-Actin Gene (ACTG1) Are Associated with Dominant Progressive Deafness (DFNA20/26)
inferred cites → https://doi.org/10.1093/emboj/cdf689 openalex-snapshot Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle
inferred cites → https://doi.org/10.1093/hmg/12.5.463 openalex-snapshot Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin
inferred cites → https://doi.org/10.1093/hmg/ddg358 openalex-snapshot PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23
inferred cites → https://doi.org/10.1121/1.381496 openalex-snapshot Postnatal development in the acoustic system of the house mouse in the light of developing masked thresholds
inferred cites → https://doi.org/10.1136/jmg.2003.011973 openalex-snapshot Novel association of hypertrophic cardiomyopathy, sensorineural deafness, and a mutation in unconventional myosin VI ( MYO6 )
inferred cites → https://doi.org/10.1242/dev.00448 openalex-snapshot Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea
inferred cites → https://doi.org/10.1242/dev.116.1.213 openalex-snapshot Actin filaments, stereocilia and hair cells of the bird cochlea VI. How the number and arrangement of stereocilia are determined
inferred cites → https://doi.org/10.1242/dev.129.10.2495 openalex-snapshot The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination
What points at this work Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred ← cites https://doi.org/10.1002/ajmg.a.34391 openalex-snapshot Genome‐wide SNP genotyping identifies the Stereocilin (STRC) gene as a major contributor to pediatric bilateral sensorineural hearing impairment
inferred ← cites https://doi.org/10.1002/cm.21159 openalex-snapshot CLIC5 stabilizes membrane‐actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI
inferred ← cites https://doi.org/10.1002/cne.22001 openalex-snapshot Patterns of expression of Bardet‐Biedl syndrome proteins in the mammalian cochlea suggest noncentrosomal functions
inferred ← cites https://doi.org/10.1002/cne.22456 openalex-snapshot Asymmetric distribution of cadherin 23 and protocadherin 15 in the kinocilial links of avian sensory hair cells
inferred ← cites https://doi.org/10.1002/dvdy.21324 openalex-snapshot Apical and lateral cell protrusions interconnect epithelial cells in live Drosophila wing imaginal discs
inferred ← cites https://doi.org/10.1002/dvdy.21598 openalex-snapshot Morphogenesis of the node and notochord: The cellular basis for the establishment and maintenance of left–right asymmetry in the mouse
inferred ← cites https://doi.org/10.1002/jcp.31003 openalex-snapshot RBM24 is required for mouse hair cell development through regulating pre‐mRNA alternative splicing and mRNA stability
inferred ← cites https://doi.org/10.1002/jez.b.21055 openalex-snapshot Evolutionary origins of vertebrate placodes: insights from developmental studies and from comparisons with other deuterostomes
inferred ← cites https://doi.org/10.1016/j.ajhg.2009.07.017 openalex-snapshot Mutations in LOXHD1, an Evolutionarily Conserved Stereociliary Protein, Disrupt Hair Cell Function in Mice and Cause Progressive Hearing Loss in Humans
inferred ← cites https://doi.org/10.1016/j.jbc.2026.113402 openalex-snapshot Hearing loss associated with CDC42 in mice and humans (Takenouchi–Kosaki syndrome): CDC42 and RHOQ synergistically function in cochlear hair cells
inferred ← cites https://doi.org/10.1016/j.ydbio.2005.12.021 openalex-snapshot Differential expression of espin isoforms during epithelial morphogenesis, stereociliogenesis and postnatal maturation in the developing inner ear
inferred ← cites https://doi.org/10.1038/ncb1219 openalex-snapshot Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia
inferred ← cites https://doi.org/10.1038/ncomms7873 openalex-snapshot Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear
inferred ← cites https://doi.org/10.1038/ng1644 openalex-snapshot Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
inferred ← cites https://doi.org/10.1086/499164 openalex-snapshot Mutations in TRIOBP, Which Encodes a Putative Cytoskeletal-Organizing Protein, Are Associated with Nonsyndromic Recessive Deafness
inferred ← cites https://doi.org/10.1093/hmg/ddi490 openalex-snapshot The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1
inferred ← cites https://doi.org/10.1093/hmg/ddr503 openalex-snapshot Whirlin interacts with espin and modulates its actin-regulatory function: an insight into the mechanism of Usher syndrome type II
inferred ← cites https://doi.org/10.1093/hmg/ddv398 openalex-snapshot Individual USH2 proteins make distinct contributions to the ankle link complex during development of the mouse cochlear stereociliary bundle
inferred ← cites https://doi.org/10.1101/2023.07.09.545606 openalex-snapshot Calcium and Integrin-binding protein 2 (CIB2) controls force sensitivity of the mechanotransducer channels in cochlear outer hair cells
inferred ← cites https://doi.org/10.1101/2024.09.24.614849 openalex-snapshot Rfx3 controls outer hair cell differentiation, maintenance, and hair bundle formation by regulating the expression of Insm1, Ikzf2 , and Triobp genes
inferred ← cites https://doi.org/10.1111/gtc.12131 openalex-snapshot Caprice/ MISP is a novel F ‐actin bundling protein critical for actin‐based cytoskeletal reorganizations
inferred ← cites https://doi.org/10.1111/jfb.12398 openalex-snapshot Identification of a gene set to evaluate the potential effects of loud sounds from seismic surveys on the ears of fishes: a study with Salmo salar
inferred ← cites https://doi.org/10.1167/iovs.06-0108 openalex-snapshot Ames Waltzer Deaf Mice Have Reduced Electroretinogram Amplitudes and Complex Alternative Splicing of Pcdh15 Transcripts
inferred ← cites https://doi.org/10.1172/jci60981 openalex-snapshot Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis
inferred ← cites https://doi.org/10.1177/1179547619871907 openalex-snapshot Report of a Novel Splicing Mutation in the MYO15A Gene in a Patient With Sensorineural Hearing Loss and Spectrum of the MYO15A Mutations
inferred ← cites https://doi.org/10.1242/dev.045138 openalex-snapshot Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape
inferred ← cites https://doi.org/10.1242/jcs.02424 openalex-snapshot PHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIa
inferred ← cites https://doi.org/10.1242/jcs.02636 openalex-snapshot Usher I syndrome: unravelling the mechanisms that underlie the cohesion of the growing hair bundle in inner ear sensory cells
inferred ← cites https://doi.org/10.1242/jcs.099242 openalex-snapshot Myosin VIIA regulates microvillus morphogenesis and interacts with cadherin Cad99C in Drosophila oogenesis
inferred ← cites https://doi.org/10.1266/ggs.16-00041 openalex-snapshot A novel missense variant in the DIAPH1 gene in a Korean family with autosomal dominant nonsyndromic hearing loss
inferred ← cites https://doi.org/10.13023/etd.2018.321 openalex-snapshot Myosin-XVa is Key Molecule in Establishing the Architecture of Mechanosensory Stereocilia Bundles of the Inner Ear Hair Cells
inferred ← cites https://doi.org/10.13023/etd.2020.410 openalex-snapshot REMODELING IN THE ACTIN CORE OF THE AUDITORY HAIR CELL STEREOCILIA AS A NOVEL COMPONENT OF TEMPORARY NOISE-INDUCED HEARING LOSS
inferred ← cites https://doi.org/10.13028/pfss-gf44 openalex-snapshot Identification and Characterization of Components of the Intraflagellar transport (IFT) Machinery: a Dissertation
inferred ← cites https://doi.org/10.1369/0022155419841013 openalex-snapshot Rho-kinase and PKCα Inhibition Induces Primary Cilia Elongation and Alters the Behavior of Undifferentiated and Differentiated Temperature-sensitive Mouse Cochlear Cells
inferred ← cites https://doi.org/10.1371/journal.pgen.1002032 openalex-snapshot Roles of the Espin Actin-Bundling Proteins in the Morphogenesis and Stabilization of Hair Cell Stereocilia Revealed in CBA/CaJ Congenic Jerker Mice
inferred ← cites https://doi.org/10.1371/journal.pone.0036074 openalex-snapshot Mutations of the Mouse ELMO Domain Containing 1 Gene (Elmod1) Link Small GTPase Signaling to Actin Cytoskeleton Dynamics in Hair Cell Stereocilia
inferred ← cites https://doi.org/10.1534/genetics.106.057372 openalex-snapshot Multiple Quantitative Trait Loci Modify Cochlear Hair Cell Degeneration in the Beethoven (Tmc1Bth) Mouse Model of Progressive Hearing Loss DFNA36
inferred ← cites https://doi.org/10.3390/ijms13078171 openalex-snapshot Proteomic Analysis of the Organ of Corti Using Nanoscale Liquid Chromatography Coupled with Tandem Mass Spectrometry
inferred ← cites https://doi.org/10.3791/2965 openalex-snapshot Investigating Outer Hair Cell Motility with a Combination of External Alternating Electrical Field Stimulation and High-speed Image Analysis
inferred ← cites https://doi.org/10.3892/ijmm.2014.1634 openalex-snapshot Myosin light chain kinase regulates hearing in mice by influencing the F-actin cytoskeleton of outer hair cells and cochleae
inferred ← cites https://doi.org/10.3892/mmr.2014.1953 openalex-snapshot Inhibition of Myo6 gene expression by co-expression of a mutant of transcription factor POU4F3 (BRN-3C) in hair cells
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