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H-NS cooperative binding to high-affinity sites in a regulatory element results in transcriptional silencing

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/bf00055322openalex-snapshot
How is osmotic regulation of transcription of the Escherichia coli proU operon achieved?
inferredcites →https://doi.org/10.1007/bf00260648openalex-snapshot
Systematic characterization of curved DNA segments randomly cloned from Escherichia coli and their functional significance
inferredcites →https://doi.org/10.1007/bf00290685openalex-snapshot
Molecular analysis of the Escherichia coli has gene encoding a DNA-binding protein, which preferentially recognizes curved DNA sequences
inferredcites →https://doi.org/10.1016/0076-6879(86)30011-9openalex-snapshot
[9] Quantitative DNase footprint titration: A method for studying protein-DNA interactions
inferredcites →https://doi.org/10.1016/0092-8674(88)90470-9openalex-snapshot
A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli
inferredcites →https://doi.org/10.1016/0092-8674(90)90458-qopenalex-snapshot
Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria
inferredcites →https://doi.org/10.1016/0092-8674(92)90354-fopenalex-snapshot
The chromatin-associated protein H-NS interacts with curved DNA to influence DNA topology and gene expression
inferredcites →https://doi.org/10.1016/0378-1119(89)90358-2openalex-snapshot
Site-directed mutagenesis by overlap extension using the polymerase chain reaction
inferredcites →https://doi.org/10.1016/j.ijmm.2006.02.017openalex-snapshot
Concert of regulators to switch on LEE expression in enterohemorrhagic Escherichia coli O157:H7: Interplay between Ler, GrlA, HNS and RpoS
inferredcites →https://doi.org/10.1016/j.jmb.2005.10.034openalex-snapshot
Environmental Control of the In vivo Oligomerization of Nucleoid Protein H-NS
inferredcites →https://doi.org/10.1016/s0021-9258(17)37411-2openalex-snapshot
Interactions of the nucleoid-associated DNA-binding protein H-NS with the regulatory region of the osmotically controlled proU operon of Escherichia coli.
inferredcites →https://doi.org/10.1016/s0300-9084(00)01213-xopenalex-snapshot
Structural basis for preferential binding of H-NS to curved DNA
inferredcites →https://doi.org/10.1021/bi00467a024openalex-snapshot
Sequence determinants for H1 binding on Escherichia coli lac and gal promoters
inferredcites →https://doi.org/10.1038/344682a0openalex-snapshot
Transcriptional silencing and thermoregulation of gene expression in Escherichia coli
inferredcites →https://doi.org/10.1038/nature05283openalex-snapshot
Bacterial chromatin organization by H-NS protein unravelled using dual DNA manipulation
inferredcites →https://doi.org/10.1038/sj.emboj.7600754openalex-snapshot
Nature and mechanism of the in vivo oligomerization of nucleoid protein H‐NS
inferredcites →https://doi.org/10.1038/sj.embor.7400729openalex-snapshot
Homeostatic regulation of supercoiling sensitivity coordinates transcription of the bacterial genome
inferredcites →https://doi.org/10.1042/bj20050143openalex-snapshot
Architecture of bacterial replication initiation complexes: orisomes from four unrelated bacteria
inferredcites →https://doi.org/10.1042/bj20050453openalex-snapshot
H-NS is a part of a thermally controlled mechanism for bacterial gene regulation
inferredcites →https://doi.org/10.1046/j.1365-2958.1997.3151679.xopenalex-snapshot
H‐NS: a modulator of environmentally regulated gene expression
inferredcites →https://doi.org/10.1046/j.1365-2958.2000.02087.xopenalex-snapshot
Suppression of FNR‐dependent transcription activation at the Escherichia coli nir promoter by Fis, IHF and H‐NS: modulation of transcription initiation by a complex nucleo‐protein assembly
inferredcites →https://doi.org/10.1046/j.1365-2958.2001.02706.xopenalex-snapshot
A molecular mechanism for the repression of transcription by the H‐NS protein
inferredcites →https://doi.org/10.1046/j.1365-2958.2003.03848.xopenalex-snapshot
ThevirFpromoter inShigella: more than just a curved DNA stretch
inferredcites →https://doi.org/10.1073/pnas.89.7.3140openalex-snapshot
A transcriptional silencer downstream of the promoter in the osmotically controlled proU operon of Salmonella typhimurium.
inferredcites →https://doi.org/10.1074/jbc.275.16.12123openalex-snapshot
The Downstream Regulatory Element of the proU Operon of Salmonella typhimurium Inhibits Open Complex Formation by RNA Polymerase at a Distance
inferredcites →https://doi.org/10.1074/jbc.m206037200openalex-snapshot
The Degree of Oligomerization of the H-NS Nucleoid Structuring Protein Is Related to Specific Binding to DNA
inferredcites →https://doi.org/10.1093/dnares/dsl009openalex-snapshot
Escherichia coli Histone-Like Protein H-NS Preferentially Binds to Horizontally Acquired DNA in Association with RNA Polymerase
inferredcites →https://doi.org/10.1093/emboj/16.12.3655openalex-snapshot
FIS activates sequential steps during transcription initiation at a stable RNA promoter
inferredcites →https://doi.org/10.1093/emboj/16.7.1795openalex-snapshot
The oligomeric structure of nucleoid protein H‐NS is necessary for recognition of intrinsically curved DNA and for DNA bending
inferredcites →https://doi.org/10.1093/nar/12.13.5321openalex-snapshot
Hla, anE. coliDNA-binding protein which accumulates in stationary phase, strongly compacts DNAin vitro
inferredcites →https://doi.org/10.1093/nar/24.12.2422openalex-snapshot
Silencing of the Escherichia Coli bgl Promoter: Effects of Template Supercoiling and Cell Extracts on Promoter Activity in vitro
inferredcites →https://doi.org/10.1093/nar/29.24.5107openalex-snapshot
An architectural role of the Escherichia coli chromatin protein FIS in organising DNA
inferredcites →https://doi.org/10.1093/nar/gkl542openalex-snapshot
Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome
inferredcites →https://doi.org/10.1101/gad.1316305openalex-snapshot
DNA looping-mediated repression by histone-like protein H-NS: specific requirement of Eσ70 as a cofactor for looping
inferredcites →https://doi.org/10.1111/j.1365-2958.2004.04467.xopenalex-snapshot
Building a bacterial orisome: emergence of new regulatory features for replication origin unwinding
inferredcites →https://doi.org/10.1111/j.1365-2958.2005.04567.xopenalex-snapshot
SspA is required for acid resistance in stationary phase by downregulation of H‐NS in Escherichia coli
inferredcites →https://doi.org/10.1111/j.1365-2958.2005.04598.xopenalex-snapshot
The role of nucleoid‐associated proteins in the organization and compaction of bacterial chromatin
inferredcites →https://doi.org/10.1111/j.1365-2958.2005.04799.xopenalex-snapshot
A genetic selection for supercoiling mutants of Escherichia coli reveals proteins implicated in chromosome structure
inferredcites →https://doi.org/10.1111/j.1365-2958.2005.04873.xopenalex-snapshot
LRP and H‐NS – cooperative partners for transcription regulation at Escherichia coli rRNA promoters
inferredcites →https://doi.org/10.1126/science.1128794openalex-snapshot
Selective Silencing of Foreign DNA with Low GC Content by the H-NS Protein in Salmonella
inferredcites →https://doi.org/10.1128/jb.173.23.7481-7490.1991openalex-snapshot
Multiple mechanisms contribute to osmotic inducibility of proU operon expression in Escherichia coli: demonstration of two osmoresponsive promoters and of a negative regulatory element within the first structural gene
inferredcites →https://doi.org/10.1128/jb.176.20.6324-6333.1994openalex-snapshot
The accumulation of glutamate is necessary for optimal growth of Salmonella typhimurium in media of high osmolality but not induction of the proU operon
inferredcites →https://doi.org/10.1128/jb.177.15.4508-4513.1995openalex-snapshot
Fine-structure deletion analysis of the transcriptional silencer of the proU operon of Salmonella typhimurium
inferredcites →https://doi.org/10.1128/jb.178.14.4176-4181.1996openalex-snapshot
Effects of H-NS and potassium glutamate on sigmaS- and sigma70-directed transcription in vitro from osmotically regulated P1 and P2 promoters of proU in Escherichia coli
inferredcites →https://doi.org/10.1128/jb.178.15.4335-4343.1996openalex-snapshot
Probing the structure, function, and interactions of the Escherichia coli H-NS and StpA proteins by using dominant negative derivatives
inferredcites →https://doi.org/10.1128/jb.181.20.6361-6370.1999openalex-snapshot
Growth Phase-Dependent Variation in Protein Composition of the Escherichia coli Nucleoid
inferredcites →https://doi.org/10.1128/jb.183.11.3515-3520.2001openalex-snapshot
Improvement in K+-Limited Growth Rate Associated with Expression of the N-Terminal Fragment of One Subunit (KdpA) of the Multisubunit Kdp Transporter inEscherichia coli
inferredcites →https://doi.org/10.1128/jb.183.22.6543-6550.2001openalex-snapshot
In Vivo Expression from the RpoS-Dependent P1 Promoter of the Osmotically Regulated proU Operon in Escherichia coli and Salmonella enterica Serovar Typhimurium: Activation by rho and hns Mutations and by Cold Stress
inferredcites →https://doi.org/10.1128/jb.187.5.1845-1848.2005openalex-snapshot
DNA Bridging: a Property Shared among H-NS-Like Proteins
inferredcites →https://doi.org/10.1128/jb.187.6.2038-2049.2005openalex-snapshot
CpxR/OmpR Interplay Regulates Curli Gene Expression in Response to Osmolarity inEscherichia coli
inferredcites →https://doi.org/10.1128/mr.53.1.121-147.1989openalex-snapshot
Physiological and genetic responses of bacteria to osmotic stress
inferredcites →https://doi.org/10.1271/bbb.58.1097openalex-snapshot
Importance of Stereospecific Positioning of the Upstreamcis-Acting DNA Element Containing a Curved DNA Structure for the Functioning of theEscherichia coli pro VPromoter
inferredcites →https://doi.org/10.1371/journal.ppat.0020081openalex-snapshot
H-NS Mediates the Silencing of Laterally Acquired Genes in Bacteria
inferredcites →https://doi.org/10.1529/biophysj.105.078774openalex-snapshot
Sequence-Dependent Basepair Opening in DNA Double Helix

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1002/2211-5463.12348openalex-snapshot
A putative curved DNA region upstream of rcsA in Escherichia coli plays a key role in transcriptional regulation by H‐ NS
inferred← citeshttps://doi.org/10.1002/9781119309697.refopenalex-snapshot
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Integration of syntactic and semantic properties of the DNA code reveals chromosomes as thermodynamic machines converting energy into information
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H-NS binding to evpB and evpC and repressing T6SS expression in fish pathogen Edwardsiella piscicida
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Comparative analysis of Aliivibrio logei luxR1 and luxR2 genes regulation in Escherichia coli cells
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A Mutational Study of Cnu Reveals Attractive Forces between Cnu and H-NS
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Identification of high-specificity H-NS binding site in LEE5 promoter of enteropathogenic Esherichia coli (EPEC)
inferred← citeshttps://doi.org/10.1007/s12551-016-0205-yopenalex-snapshot
DNA supercoiling is a fundamental regulatory principle in the control of bacterial gene expression
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The regulatory role of DNA supercoiling in nucleoprotein complex assembly and genetic activity
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DNA supercoiling is a fundamental regulatory principle in the control of bacterial gene expression
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The Impact of Gene Silencing on Horizontal Gene Transfer and Bacterial Evolution
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Cooperative effects on the compaction of DNA fragments by the nucleoid protein H-NS and the crowding agent PEG probed by Magnetic Tweezers
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Protein-Mediated Molecular Bridging: A Key Mechanism in Biopolymer Organization
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A Model of H-NS Mediated Compaction of Bacterial DNA
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H-NS Regulates Gene Expression and Compacts the Nucleoid: Insights from Single-Molecule Experiments
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Role of Salt Valency in the Switch of H-NS Proteins between DNA-Bridging and DNA-Stiffening Modes
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“Anticipated” nucleosome positioning pattern in prokaryotes
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In vitro studies of DNA condensation by bridging protein in a crowding environment
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DNA Sequence-Directed Cooperation between Nucleoid-Associated Proteins
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Bacterial H-NS contacts DNA at the same irregularly spaced sites in both bridged and hemi-sequestered linear filaments
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On the Origin of the Selectivity of Plasmidic H-NS towards Horizontally Acquired DNA: Linking H-NS Oligomerization and Cooperative DNA Binding
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Structural Studies on the M. tuberculosis Nucleoid-associated-Protein, NapA, Indicates DNA Bridging Mechanism
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Modeling feedback loops in the H-NS-mediated regulation of the Escherichia coli bgl operon
inferred← citeshttps://doi.org/10.1016/j.mib.2008.02.011openalex-snapshot
New insights into transcriptional regulation by H-NS
inferred← citeshttps://doi.org/10.1016/j.mib.2011.01.003openalex-snapshot
Pervasive regulation of nucleoid structure and function by nucleoid-associated proteins
inferred← citeshttps://doi.org/10.1016/j.mib.2011.12.014openalex-snapshot
Silencing of foreign DNA in bacteria
inferred← citeshttps://doi.org/10.1016/j.mib.2015.01.009openalex-snapshot
H-NS and RNA polymerase: a love–hate relationship?
inferred← citeshttps://doi.org/10.1016/j.micinf.2016.02.001openalex-snapshot
New insights about excisable pathogenicity islands in Salmonella and their contribution to virulence
inferred← citeshttps://doi.org/10.1016/j.micpath.2016.06.003openalex-snapshot
Transcription of exsD is repressed directly by H-NS in Vibrio parahaemolyticus
inferred← citeshttps://doi.org/10.1016/j.micres.2016.07.008openalex-snapshot
The DNA–mimic antirestriction proteins ArdA ColIB-P9, Arn T4, and Ocr T7 as activators of H-NS-dependent gene transcription
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DNA sequence-specific dimeric bisbenzimidazoles DBP(n) and DBPA(n) as inhibitors of H-NS silencing in bacterial cells
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Phosphorylation of the prokaryotic histone-like protein H-NS modulates bacterial virulence in Salmonella Typhimurium
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H-NS-like nucleoid-associated proteins, mobile genetic elements and horizontal gene transfer in bacteria
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Nucleoid-associated proteins encoded on plasmids: Occurrence and mode of function
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Characterization of Acr2, an H-NS-like protein encoded on A/C2-type plasmids
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Regulation of pel genes, major virulence factors in the plant pathogen bacterium Dickeya dadantii, is mediated by cooperative binding of the nucleoid-associated protein H-NS
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H-NS: an overarching regulator of the Vibrio cholerae life cycle
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Building bridges within the bacterial chromosome
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Success in incorporating horizontally transferred genes: the H-NS protein
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Use of DNA Length Variation to Detect Periodicities in Positively Cooperative, Nonspecific Binding
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Adaptation of DNA to Protein Binding Revealed by Spectroscopy and Molecular Simulation
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The High-Precision Solution Structure of Yersinia Modulating Protein YmoA Provides Insight into Interaction with H-NS
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Evolutionary expansion of a regulatory network by counter-silencing
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Horizontally acquired AT-rich genes in Escherichia coli cause toxicity by sequestering RNA polymerase
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The environmentally-regulated interplay between local three-dimensional chromatin organisation and transcription of proVWX in E. coli
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Transcription-driven DNA supercoiling counteracts H-NS-mediated gene silencing in bacterial chromatin
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Overexpression of the third H-NS paralogue H-NS2 compensates fitness loss in hns mutants of the enteroaggregative Escherichia coli strain 042
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Nucleoprotein filament formation is the structural basis for bacterial protein H-NS gene silencing
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Intrinsic In vivo Modulators: Negative Supercoiling and the Constituents of the Bacterial Nucleoid
inferred← citeshttps://doi.org/10.1039/b907227fopenalex-snapshot
Nucleosome positioning—what do we really know?
inferred← citeshttps://doi.org/10.1039/c2sm25789kopenalex-snapshot
Electrostatics of DNA compaction in viruses, bacteria and eukaryotes: functional insights and evolutionary perspective
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Bacterial nucleoid structure probed by active drag and resistive pulse sensing
inferred← citeshttps://doi.org/10.1039/c3sm51214bopenalex-snapshot
Effect of H-NS on the elongation and compaction of single DNA molecules in a nanospace
inferred← citeshttps://doi.org/10.1039/c5sm03076eopenalex-snapshot
Structure of the H-NS–DNA nucleoprotein complex
inferred← citeshttps://doi.org/10.1042/bj20120876openalex-snapshot
Temperature-dependence of the DnaA–DNA interaction and its effect on the autoregulation of dnaA expression
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DNA thermodynamics shape chromosome organization and topology
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Structure and function of bacterial H-NS protein
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Bacterial pathogen gene regulation: a DNA-structure-centred view of a protein-dominated domain
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Structure of PlcR: Insights into virulence regulation and evolution of quorum sensing in Gram-positive bacteria
inferred← citeshttps://doi.org/10.1073/pnas.0808215105openalex-snapshot
H-NS family members function coordinately in an opportunistic pathogen
inferred← citeshttps://doi.org/10.1073/pnas.0913551107openalex-snapshot
Lsr2 is a nucleoid-associated protein that targets AT-rich sequences and virulence genes in Mycobacterium tuberculosis
inferred← citeshttps://doi.org/10.1073/pnas.1006966107openalex-snapshot
H-NS forms a superhelical protein scaffold for DNA condensation
inferred← citeshttps://doi.org/10.1073/pnas.1102544108openalex-snapshot
Structural basis for recognition of AT-rich DNA by unrelated xenogeneic silencing proteins
inferred← citeshttps://doi.org/10.1073/pnas.1322033111openalex-snapshot
DNA looping-dependent autorepression of LEE1 P1 promoters by Ler in enteropathogenic Escherichia coli (EPEC)
inferred← citeshttps://doi.org/10.1073/pnas.1716721114openalex-snapshot
Charged residues in the H-NS linker drive DNA binding and gene silencing in single cells
inferred← citeshttps://doi.org/10.1073/pnas.2203011119openalex-snapshot
Pervasive transcription enhances the accessibility of H-NS–silenced promoters and generates bistability in Salmonella virulence gene expression
inferred← citeshttps://doi.org/10.1074/jbc.m109.044313openalex-snapshot
Sequence-specific Recognition of DNA by the C-terminal Domain of Nucleoid-associated Protein H-NS
inferred← citeshttps://doi.org/10.1074/jbc.m111.266619openalex-snapshot
SlyA Protein Activates fimB Gene Expression and Type 1 Fimbriation in Escherichia coli K-12
inferred← citeshttps://doi.org/10.1074/jbc.m113.455378openalex-snapshot
Structural Insights into the Regulation of Foreign Genes in Salmonella by the Hha/H-NS Complex
inferred← citeshttps://doi.org/10.1074/jbc.m114.590851openalex-snapshot
The T4 Phage DNA Mimic Protein Arn Inhibits the DNA Binding Activity of the Bacterial Histone-like Protein H-NS
inferred← citeshttps://doi.org/10.1074/jbc.m114.626705openalex-snapshot
Transcriptional Repressor TrmBL2 from Thermococcus kodakarensis Forms Filamentous Nucleoprotein Structures and Competes with Histones for DNA Binding in a Salt- and DNA Supercoiling-dependent Manner
inferred← citeshttps://doi.org/10.1074/jbc.m117.780239openalex-snapshot
Spatial organization of DNA sequences directs the assembly of bacterial chromatin by a nucleoid-associated protein
inferred← citeshttps://doi.org/10.1074/jbc.m702753200openalex-snapshot
Repression by Binding of H-NS within the Transcription Unit
inferred← citeshttps://doi.org/10.1074/jbc.m709843200openalex-snapshot
Overcoming H-NS-mediated Transcriptional Silencing of Horizontally Acquired Genes by the PhoP and SlyA Proteins in Salmonella enterica
inferred← citeshttps://doi.org/10.1080/073911010010524942openalex-snapshot
The DNA Sequence-dependence of Nucleosome Positioningin vivoandin vitro
inferred← citeshttps://doi.org/10.1080/10409230802528488openalex-snapshot
The Major Architects of Chromatin: Architectural Proteins in Bacteria, Archaea and Eukaryotes
inferred← citeshttps://doi.org/10.1091/mbc.e10-08-0668openalex-snapshot
Histone and TK0471/TrmBL2 form a novel heterogeneous genome architecture in the hyperthermophilic archaeonThermococcus kodakarensis
inferred← citeshttps://doi.org/10.1093/dnares/dst008openalex-snapshot
Functions of the Hha and YdgT Proteins in Transcriptional Silencing by the Nucleoid Proteins, H-NS and StpA, in Escherichia coli
inferred← citeshttps://doi.org/10.1093/femsle/fnu049openalex-snapshot
IHF is a trans-acting factor implicated in the regulation of the proU P2 promoter
inferred← citeshttps://doi.org/10.1093/femsle/fnx021openalex-snapshot
Characterization of the regulatory function of the H-NS protein in the benthic bacterium Shewanella piezotolerans WP3 under cold conditions
inferred← citeshttps://doi.org/10.1093/femsre/fuab032openalex-snapshot
Hierarchy of transcription factor network in Escherichia coli K-12: H-NS-mediated silencing and Anti-silencing by global regulators
inferred← citeshttps://doi.org/10.1093/molbev/msab136openalex-snapshot
Xenogeneic Silencing and Bacterial Genome Evolution: Mechanisms for DNA Recognition Imply Multifaceted Roles of Xenogeneic Silencers
inferred← citeshttps://doi.org/10.1093/nar/gkab137openalex-snapshot
Xenogeneic silencing relies on temperature-dependent phosphorylation of the host H-NS protein in Shewanella
inferred← citeshttps://doi.org/10.1093/nar/gkad088openalex-snapshot
Localized modulation of DNA supercoiling, triggered by the Shigella anti-silencer VirB, is sufficient to relieve H-NS-mediated silencing
inferred← citeshttps://doi.org/10.1093/nar/gkad1014openalex-snapshot
Decoding dissociation of sequence-specific protein–DNA complexes with non-equilibrium simulations
inferred← citeshttps://doi.org/10.1093/nar/gkad370openalex-snapshot
Attenuation of a DNA cruciform by a conserved regulator directs T3SS1 mediated virulence in Vibrio parahaemolyticus
inferred← citeshttps://doi.org/10.1093/nar/gkad495openalex-snapshot
Widespread CRISPR-derived RNA regulatory elements in CRISPR-Cas systems
inferred← citeshttps://doi.org/10.1093/nar/gkae090openalex-snapshot
Molecular and thermodynamic determinants of self-assembly and hetero-oligomerization in the enterobacterial thermo-osmo-regulatory protein H-NS
inferred← citeshttps://doi.org/10.1093/nar/gkae459openalex-snapshot
Structure of the E. coli nucleoid-associated protein YejK reveals a novel DNA binding clamp
inferred← citeshttps://doi.org/10.1093/nar/gkaf928openalex-snapshot
Abundant bacterial nucleoid-associated protein H-NS limits plasmid transfer through mechanical modification of DNA
inferred← citeshttps://doi.org/10.1093/nar/gkm1162openalex-snapshot
Lsr2 of Mycobacterium tuberculosis is a DNA-bridging protein
inferred← citeshttps://doi.org/10.1093/nar/gkm712openalex-snapshot
High-affinity DNA binding sites for H-NS provide a molecular basis for selective silencing within proteobacterial genomes
inferred← citeshttps://doi.org/10.1093/nar/gkp574openalex-snapshot
A translational signature for nucleosome positioning in vivo
inferred← citeshttps://doi.org/10.1093/nar/gkp672openalex-snapshot
H-NS binds with high affinity to the Tn10 transpososome and promotes transpososome stabilization
inferred← citeshttps://doi.org/10.1093/nar/gkq064openalex-snapshot
Mycobacterium tuberculosis nucleoid-associated DNA-binding protein H-NS binds with high-affinity to the Holliday junction and inhibits strand exchange promoted by RecA protein
inferred← citeshttps://doi.org/10.1093/nar/gkq934openalex-snapshot
Direct and indirect effects of H-NS and Fis on global gene expression control in Escherichia coli
inferred← citeshttps://doi.org/10.1093/nar/gks014openalex-snapshot
The nucleoid-associated proteins H-NS and FIS modulate the DNA supercoiling response of the pel genes, the major virulence factors in the plant pathogen bacterium Dickeya dadantii
inferred← citeshttps://doi.org/10.1093/nar/gkt325openalex-snapshot
Genome conformation capture reveals that the Escherichia coli chromosome is organized by replication and transcription
inferred← citeshttps://doi.org/10.1093/nar/gkt748openalex-snapshot
Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
inferred← citeshttps://doi.org/10.1093/nar/gku1052openalex-snapshot
Time-resolved assembly of a nucleoprotein complex between Shigella flexneri virF promoter and its transcriptional repressor H-NS
inferred← citeshttps://doi.org/10.1093/nar/gky1299openalex-snapshot
H-NS uses an autoinhibitory conformational switch for environment-controlled gene silencing
inferred← citeshttps://doi.org/10.1093/nar/gky826openalex-snapshot
A single molecule analysis of H-NS uncouples DNA binding affinity from DNA specificity
inferred← citeshttps://doi.org/10.1093/nar/gkz1089openalex-snapshot
Global H-NS counter-silencing by LuxR activates quorum sensing gene expression
inferred← citeshttps://doi.org/10.1093/nar/gkz1226openalex-snapshot
Structural basis for osmotic regulation of the DNA binding properties of H-NS proteins
inferred← citeshttps://doi.org/10.1098/rsob.190223openalex-snapshot
The architects of bacterial DNA bridges: a structurally and functionally conserved family of proteins
inferred← citeshttps://doi.org/10.1099/mic.0.000780openalex-snapshot
Direct inhibition of transcription in vitro by the isolated N-terminal domain of the Escherichia coli nucleoid-associated protein H-NS and by its paralogue Hha
inferred← citeshttps://doi.org/10.1099/mic.0.028597-0openalex-snapshot
The DNA static curvature has a role in the regulation of the ompS1 porin gene in Salmonella enterica serovar Typhi
inferred← citeshttps://doi.org/10.1099/mic.0.2008/018408-0openalex-snapshot
Effect of upstream curvature and transcription factors H-NS and LRP on the efficiency of Escherichia coli rRNA promoters P1 and P2 – a phasing analysis
inferred← citeshttps://doi.org/10.1099/mic.0.2008/020693-0openalex-snapshot
Anti-silencing: overcoming H-NS-mediated repression of transcription in Gram-negative enteric bacteria
inferred← citeshttps://doi.org/10.1099/mic.0.2008/023382-0openalex-snapshot
Ler interdomain linker is essential for anti-silencing activity in enteropathogenic Escherichia coli
inferred← citeshttps://doi.org/10.1101/2023.03.03.530964openalex-snapshot
Widespread CRISPR repeat-like RNA regulatory elements in CRISPR-Cas systems
inferred← citeshttps://doi.org/10.1101/2023.10.26.564199openalex-snapshot
Transcription-driven DNA supercoiling activates bacterial chromatin at a distance
inferred← citeshttps://doi.org/10.1101/gad.1883510openalex-snapshot
A divalent switch drives H-NS/DNA-binding conformations between stiffening and bridging modes
inferred← citeshttps://doi.org/10.1101/gad.234336.113openalex-snapshot
Widespread suppression of intragenic transcription initiation by H-NS
inferred← citeshttps://doi.org/10.1101/gad.290312.116openalex-snapshot
Colocalization of distant chromosomal loci in space in E. coli: a bacterial nucleolus
inferred← citeshttps://doi.org/10.1111/febs.12297openalex-snapshot
Protein oligomers studied by solid‐state NMR – the case of the full‐length nucleoid‐associated protein histone‐like nucleoid structuring protein
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2007.05907.xopenalex-snapshot
The RovA regulons of Yersinia enterocolitica and Yersinia pestis are distinct: evidence that many RovA‐regulated genes were acquired more recently than the core genome
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2007.05916.xopenalex-snapshot
Expression of the Fis protein is sustained in late‐exponential‐ and stationary‐phase cultures of Salmonella enterica serovar Typhimurium grown in the absence of aeration
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2007.05958.xopenalex-snapshot
LeuO antagonizes H‐NS and StpA‐dependent repression in Salmonella enterica ompS1
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2008.06253.xopenalex-snapshot
Selective repression by Fis and H‐NS at the Escherichia coli dps promoter
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2008.06266.xopenalex-snapshot
Fine‐tuned growth phase control of dps, encoding a DNA protection protein, by FIS and H‐NS
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2009.06754.xopenalex-snapshot
Investigation of the self‐association and hetero‐association interactions of H‐NS and StpA from Enterobacteria
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2010.07073.xopenalex-snapshot
Identification and characterization of E. coli CRISPR‐cas promoters and their silencing by H‐NS
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2010.07173.xopenalex-snapshot
Genome‐wide analysis of the H‐NS and Sfh regulatory networks in Salmonella Typhimurium identifies a plasmid‐encoded transcription silencing mechanism
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2010.07185.xopenalex-snapshot
DnaA-ATP acts as a molecular switch to control levels of ribonucleotide reductase expression in Escherichia coli
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2010.07315.xopenalex-snapshot
H‐NS‐mediated repression of CRISPR‐based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2010.07378.xopenalex-snapshot
High-order oligomerization is required for the function of the H-NS family member MvaT in Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2011.07818.xopenalex-snapshot
Novel roles of LeuO in transcription regulation of E. coli genome: antagonistic interplay with the universal silencer H-NS
inferred← citeshttps://doi.org/10.1111/j.1574-6976.2008.00155.xopenalex-snapshot
DNA bridging and antibridging: a role for bacterial nucleoid-associated proteins in regulating the expression of laterally acquired genes
inferred← citeshttps://doi.org/10.1111/lam.12316openalex-snapshot
A new target for the old regulator: H-NS suppress T6SS secretory protein EvpP, the major virulence factor in the fish pathogen Edwardsiella tarda
inferred← citeshttps://doi.org/10.1111/mmi.12012openalex-snapshot
Gene silencing by H‐NS from distal DNA site
inferred← citeshttps://doi.org/10.1111/mmi.12554openalex-snapshot
YmoA negatively controls the expression of insecticidal genes in Y ersinia enterocolitica
inferred← citeshttps://doi.org/10.1111/mmi.13919openalex-snapshot
The curli regulator CsgD mediates stationary phase counter‐silencing of csgBA in Salmonella Typhimurium
inferred← citeshttps://doi.org/10.1111/mmi.13926openalex-snapshot
Interference of transcription across H‐NS binding sites and repression by H‐NS
inferred← citeshttps://doi.org/10.1111/mmi.13932openalex-snapshot
Insights into transcriptional silencing and anti‐silencing in Shigella flexneri: a detailed molecular analysis of the icsP virulence locus
inferred← citeshttps://doi.org/10.1111/mmi.15062openalex-snapshot
Three‐dimensional chromosome re‐modelling: The integral mechanism of transcription regulation in bacteria
inferred← citeshttps://doi.org/10.1111/mmi.15283openalex-snapshot
Bacterial chromatin proteins, transcription, and DNA topology: Inseparable partners in the control of gene expression
inferred← citeshttps://doi.org/10.1111/mmi.70036openalex-snapshot
DNA Binding by BosR Controls RpoS ‐Dependent and ‐Independent Gene Expression in Borrelia burgdorferi
inferred← citeshttps://doi.org/10.1128/9781555816841.ch9openalex-snapshot
Osmotic Stress
inferred← citeshttps://doi.org/10.1128/9781555819217.ch29openalex-snapshot
Transposons Tn10 and Tn5
inferred← citeshttps://doi.org/10.1128/aem.00297-16openalex-snapshot
The Histone-Like Nucleoid Structuring Protein (H-NS) Is a Negative Regulator of the Lateral Flagellar System in the Deep-Sea Bacterium Shewanella piezotolerans WP3
inferred← citeshttps://doi.org/10.1128/aem.02114-14openalex-snapshot
The Intimin-Like Protein FdeC Is Regulated by H-NS and Temperature in Enterohemorrhagic Escherichia coli
inferred← citeshttps://doi.org/10.1128/ecosalplus.2.6openalex-snapshot
The Nucleoid: an Overview
inferred← citeshttps://doi.org/10.1128/ecosalplus.5.4.5openalex-snapshot
Osmotic Stress
inferred← citeshttps://doi.org/10.1128/ecosalplus.esp-0001-2022openalex-snapshot
Spatio-temporal organization of the E. coli chromosome from base to cellular length scales
inferred← citeshttps://doi.org/10.1128/iai.00096-10openalex-snapshot
Taming the Elephant: Salmonella Biology, Pathogenesis, and Prevention
inferred← citeshttps://doi.org/10.1128/iai.00198-15openalex-snapshot
H-NS Silencing of the Salmonella Pathogenicity Island 6-Encoded Type VI Secretion System Limits Salmonella enterica Serovar Typhimurium Interbacterial Killing
inferred← citeshttps://doi.org/10.1128/iai.01302-15openalex-snapshot
Regulation of Expression of Uropathogenic Escherichia coli Nonfimbrial Adhesin TosA by PapB Homolog TosR in Conjunction with H-NS and Lrp
inferred← citeshttps://doi.org/10.1128/jb.00054-19openalex-snapshot
H-NS Family Members MvaT and MvaU Regulate the Pseudomonas aeruginosa Type III Secretion System
inferred← citeshttps://doi.org/10.1128/jb.00072-20openalex-snapshot
The Antiactivator of Type III Secretion, OspD1, Is Transcriptionally Regulated by VirB and H-NS from Remote Sequences in Shigella flexneri
inferred← citeshttps://doi.org/10.1128/jb.00089-08openalex-snapshot
Integration Host Factor Positively Regulates Virulence Gene Expression in Vibrio cholerae
inferred← citeshttps://doi.org/10.1128/jb.00137-22openalex-snapshot
The AraC/XylS Protein MxiE and Its Coregulator IpgC Control a Negative Feedback Loop in the Transcriptional Cascade That Regulates Type III Secretion in Shigella flexneri
inferred← citeshttps://doi.org/10.1128/jb.00187-21openalex-snapshot
H-NS and ToxT Inversely Control Cholera Toxin Production by Binding to Overlapping DNA Sequences
inferred← citeshttps://doi.org/10.1128/jb.00212-13openalex-snapshot
Characterization of the ospZ Promoter in Shigella flexneri and Its Regulation by VirB and H-NS
inferred← citeshttps://doi.org/10.1128/jb.00308-21openalex-snapshot
Long-Distance Effects of H-NS Binding in the Control of hilD Expression in the Salmonella SPI1 Locus
inferred← citeshttps://doi.org/10.1128/jb.00469-19openalex-snapshot
Growth Phase-Dependent Chromosome Condensation and Heat-Stable Nucleoid-Structuring Protein Redistribution in Escherichia coli under Osmotic Stress
inferred← citeshttps://doi.org/10.1128/jb.00531-10openalex-snapshot
H-NS Silences gfp , the Green Fluorescent Protein Gene: gfp TCD Is a Genetically Remastered gfp Gene with Reduced Susceptibility to H-NS-Mediated Transcription Silencing and with Enhanced Translation
inferred← citeshttps://doi.org/10.1128/jb.00733-08openalex-snapshot
Lsr2 of Mycobacterium Represents a Novel Class of H-NS-Like Proteins
inferred← citeshttps://doi.org/10.1128/jb.00932-12openalex-snapshot
Basis for the Essentiality of H-NS Family Members in Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1128/jb.01343-09openalex-snapshot
H-NS Binding and Repression of the ctx Promoter in Vibrio cholerae
inferred← citeshttps://doi.org/10.1128/jb.01388-07openalex-snapshot
The Leucine-Responsive Regulatory Protein, Lrp, Activates Transcription of thefimOperon inSalmonella entericaSerovar Typhimurium via thefimZRegulatory Gene
inferred← citeshttps://doi.org/10.1128/jb.01388-08openalex-snapshot
Regulation of Expression of the Region 3 Promoter of theEscherichia coliK5 Capsule Gene Cluster Involves H-NS, SlyA, and a Large 5′ Untranslated Region
inferred← citeshttps://doi.org/10.1128/jb.01447-07openalex-snapshot
Regulation of the yjjQ - bglJ Operon, Encoding LuxR-Type Transcription Factors, and the Divergent yjjP Gene by H-NS and LeuO
inferred← citeshttps://doi.org/10.1128/jb.01513-09openalex-snapshot
Regulation of pga Operon Expression and Biofilm Formation in Actinobacillus pleuropneumoniae by σ E and H-NS
inferred← citeshttps://doi.org/10.1128/jb.02081-12openalex-snapshot
Regulation of Lipid Biosynthesis, Sliding Motility, and Biofilm Formation by a Membrane-Anchored Nucleoid-Associated Protein of Mycobacterium tuberculosis
inferred← citeshttps://doi.org/10.1128/jb.05557-11openalex-snapshot
Rational Design of an Artificial Genetic Switch: Co-Option of the H-NS-Repressed proU Operon by the VirB Virulence Master Regulator
inferred← citeshttps://doi.org/10.1128/jb.06812-11openalex-snapshot
CovR Alleviates Transcriptional Silencing by a Nucleoid-Associated Histone-Like Protein in Streptococcus mutans
inferred← citeshttps://doi.org/10.1128/mbio.00773-17openalex-snapshot
Bacterial-Chromatin Structural Proteins Regulate the Bimodal Expression of the Locus of Enterocyte Effacement (LEE) Pathogenicity Island in Enteropathogenic Escherichia coli
inferred← citeshttps://doi.org/10.1128/mbio.01226-19openalex-snapshot
The Symmetrical Wave Pattern of Base-Pair Substitution Rates across the Escherichia coli Chromosome Has Multiple Causes
inferred← citeshttps://doi.org/10.1128/mbio.01519-23openalex-snapshot
VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities
inferred← citeshttps://doi.org/10.1128/microbiolspec.mdna3-0002-2014openalex-snapshot
Transposons Tn 10 and Tn 5
inferred← citeshttps://doi.org/10.1128/mmbr.00027-10openalex-snapshot
The Accessory Genome of Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1128/msystems.01142-21openalex-snapshot
Global Chromosome Topology and the Two-Component Systems in Concerted Manner Regulate Transcription in Streptomyces
inferred← citeshttps://doi.org/10.1134/s1022795417020065openalex-snapshot
Histone-like protein H-NS as a negative regulator of quorum sensing systems in gram-negative bacteria
inferred← citeshttps://doi.org/10.1146/annurev-biochem-072911-172315openalex-snapshot
CRISPR-Mediated Adaptive Immune Systems in Bacteria and Archaea
inferred← citeshttps://doi.org/10.1146/annurev-micro-033021-113232openalex-snapshot
Multiscale Dynamic Structuring of Bacterial Chromosomes
inferred← citeshttps://doi.org/10.1146/annurev-micro-102215-095301openalex-snapshot
Xenogeneic Silencing and Its Impact on Bacterial Genomes
inferred← citeshttps://doi.org/10.1146/annurev.genet.42.110807.091653openalex-snapshot
The Organization of the Bacterial Genome
inferred← citeshttps://doi.org/10.1159/000368850openalex-snapshot
Function of Nucleoid-Associated Proteins in Chromosome Structuring and Transcriptional Regulation
inferred← citeshttps://doi.org/10.1159/000368851openalex-snapshot
Genomic Looping: A Key Principle of Chromatin Organization
inferred← citeshttps://doi.org/10.1186/1759-8753-3-7openalex-snapshot
Identification of basepairs within Tn5 termini that are critical sfor H-NS binding to the transpososome and regulation of Tn5 transposition
inferred← citeshttps://doi.org/10.1271/bbb.100841openalex-snapshot
Oligomerization and DNA-Binding Capacity of Pmr, a Histone-Like Protein H1 (H-NS) Family Protein Encoded on IncP-7 Carbazole-Degradative Plasmid pCAR1
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1006845openalex-snapshot
Predicting the mechanism and rate of H-NS binding to AT-rich DNA
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