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Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway

https://doi.org/10.1038/onc.2009.335
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/978-0-387-74039-3_1openalex-snapshot
Overview of Resistance to Systemic Therapy in Patients with Breast Cancer
inferredcites →https://doi.org/10.1007/978-1-4615-5873-6_5openalex-snapshot
A temporal and biochemical link between growth factor-activated MAP kinases, cyclin D1 induction and cell cycle entry
inferredcites →https://doi.org/10.1007/s10495-005-3275-zopenalex-snapshot
Induction of apoptosis in prostate tumor PC-3 cells and inhibition of xenograft prostate tumor growth by the vanilloid capsaicin
inferredcites →https://doi.org/10.1016/j.bbrc.2006.12.179openalex-snapshot
Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: How vanilloids cause non-vanilloid receptor mediated cell death
inferredcites →https://doi.org/10.1016/j.ccr.2006.07.015openalex-snapshot
Co-opted integrin signaling in ErbB2-induced mammary tumor progression
inferredcites →https://doi.org/10.1016/j.lfs.2005.07.019openalex-snapshot
Apoptosis induction by dohevanil, a DHA substitutive analog of capsaicin, in MCF-7 cells
inferredcites →https://doi.org/10.1016/s0027-9684(15)31344-4openalex-snapshot
Higher Incidence of Aggressive Breast Cancers in African-American Women: A Review
inferredcites →https://doi.org/10.1016/s0304-3835(01)00426-8openalex-snapshot
Capsaicin-induced apoptosis in SK-Hep-1 hepatocarcinoma cells involves Bcl-2 downregulation and caspase-3 activation
inferredcites →https://doi.org/10.1016/s0960-0760(02)00251-0openalex-snapshot
A mechanism of drug resistance to tamoxifen in breast cancer
inferredcites →https://doi.org/10.1038/onc.2008.207openalex-snapshot
HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
inferredcites →https://doi.org/10.1038/sj.onc.1201228openalex-snapshot
Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway
inferredcites →https://doi.org/10.1038/sj.onc.1204082openalex-snapshot
The EGF receptor family as targets for cancer therapy
inferredcites →https://doi.org/10.1038/sj.onc.1204541openalex-snapshot
Temporal and quantitative regulation of mitogen-activated protein kinase (MAPK) modulates cell motility and invasion
inferredcites →https://doi.org/10.1038/sj.onc.1206779openalex-snapshot
Biologic and therapeutic role of HER2 in cancer
inferredcites →https://doi.org/10.1073/pnas.92.6.1831openalex-snapshot
Capsaicin inhibits preferentially the NADH oxidase and growth of transformed cells in culture.
inferredcites →https://doi.org/10.1080/10915810601117943openalex-snapshot
2006 American College of Toxicology Distinguished Service Award Lecture: Has Quantitative Risk Assessment Been of Benefit to the Science of Toxicology?
inferredcites →https://doi.org/10.1089/1096620041938713openalex-snapshot
Capsaicin, a Spicy Component of Hot Pepper, Induces Apoptosis by Activation of the Peroxisome Proliferator-Activated Receptor γ in HT-29 Human Colon Cancer Cells
inferredcites →https://doi.org/10.1093/jn/133.11.3785sopenalex-snapshot
Nutritional Approaches to Late Toxicities of Adjuvant Chemotherapy in Breast Cancer Survivors
inferredcites →https://doi.org/10.1093/jnci/92.5.418openalex-snapshot
A Ligand of Peroxisome Proliferator-Activated Receptor gamma, Retinoids, and Prevention of Preneoplastic Mammary Lesions
inferredcites →https://doi.org/10.1093/jnci/93.14.1103openalex-snapshot
Induction of Atypical Ductal Hyperplasia in Mouse Mammary Gland Organ Culture
inferredcites →https://doi.org/10.1093/jnci/94.17.1281openalex-snapshot
Examining the Role of Mitochondrial Respiration in Vanilloid-Induced Apoptosis
inferredcites →https://doi.org/10.1093/jnci/95.12.896openalex-snapshot
Vitamin D2 Analog 19-nor-1,25-Dihydroxyvitamin D2: Antitumor Activity Against Leukemia, Myeloma, and Colon Cancer Cells
inferredcites →https://doi.org/10.1111/j.1749-6632.1999.tb08734.xopenalex-snapshot
Update from Asia: Asian Studies on Cancer Chemoprevention
inferredcites →https://doi.org/10.1158/0008-5472.650.65.2openalex-snapshot
Endogenous Anti-HER2 Antibodies Block HER2 Phosphorylation and Signaling through Extracellular Signal-Regulated Kinase
inferredcites →https://doi.org/10.1158/0008-5472.can-03-1670openalex-snapshot
Induction of Apoptosis in Leukemic Cells by Homovanillic Acid Derivative, Capsaicin, through Oxidative Stress
inferredcites →https://doi.org/10.1158/0008-5472.can-04-0396openalex-snapshot
Involvement of Ras Activation in Human Breast Cancer Cell Signaling, Invasion, and Anoikis
inferredcites →https://doi.org/10.1158/0008-5472.can-05-0087openalex-snapshot
Capsaicin, a Component of Red Peppers, Inhibits the Growth of Androgen-Independent, p53 Mutant Prostate Cancer Cells
inferredcites →https://doi.org/10.1158/1078-0432.ccr-05-1554openalex-snapshot
The Epidermal Growth Factor Receptor Pathway: A Model for Targeted Therapy
inferredcites →https://doi.org/10.1158/1078-0432.ccr-08-0581openalex-snapshot
Acquired Resistance to Small Molecule ErbB2 Tyrosine Kinase Inhibitors
inferredcites →https://doi.org/10.1172/jci119309openalex-snapshot
Hyperexpression of mitogen-activated protein kinase in human breast cancer.
inferredcites →https://doi.org/10.1186/bcr2103openalex-snapshot
Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas
inferredcites →https://doi.org/10.1200/jco.2003.01.504openalex-snapshot
Status of Epidermal Growth Factor Receptor Antagonists in the Biology and Treatment of Cancer
inferredcites →https://doi.org/10.3109/10408448209003371openalex-snapshot
Capsaicin — A Literature Survey
inferredcites →https://doi.org/10.3748/wjg.v11.i40.6254openalex-snapshot
Capsaicin-induced cell death in a human gastric adenocarcinoma cell line

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Synthesis and Evaluation of the Biological Properties of Novel Boron-Containing Capsaicin Derivatives on Human Cancer Cell Lines
inferred← citeshttps://doi.org/10.1002/9781394270576.ch2openalex-snapshot
Antioxidants in Cancer Prevention
inferred← citeshttps://doi.org/10.1002/ardp.201400233openalex-snapshot
Novel Capsaicin Analogues as Potential Anticancer Agents: Synthesis, Biological Evaluation, and In Silico Approach
inferred← citeshttps://doi.org/10.1002/fft2.70135openalex-snapshot
Natural Products Targeting the EGFR/HER2 Axis in Tumorigenesis: Interpretation of Molecular Mechanisms and Recent Insights Into Synergistic Strategies for Cancer Therapy
inferred← citeshttps://doi.org/10.1002/ptr.8107openalex-snapshot
Capsaicin: A chili pepper bioactive phytocompound with a potential role in suppressing cancer development and progression
inferred← citeshttps://doi.org/10.1007/978-1-4614-5836-4_94openalex-snapshot
TRPV1 Activators (“Vanilloids”) as Neurotoxins
inferred← citeshttps://doi.org/10.1007/978-1-4939-7018-6_15openalex-snapshot
Fermented Vegetables
inferred← citeshttps://doi.org/10.1007/978-3-0348-0828-6_8openalex-snapshot
The Potential Antitumor Effects of Capsaicin
inferred← citeshttps://doi.org/10.1007/978-3-319-05161-1_19openalex-snapshot
TRP Modulation by Natural Compounds
inferred← citeshttps://doi.org/10.1007/978-94-007-0526-5_1openalex-snapshot
An Overview of Anticancer Herbal Medicines
inferred← citeshttps://doi.org/10.1007/978-94-007-4575-9openalex-snapshot
Natural compounds as inducers of cell death
inferred← citeshttps://doi.org/10.1007/978-94-007-4575-9_8openalex-snapshot
Induction of Apoptosis by Polyphenolic Compounds in Cancer Cells
inferred← citeshttps://doi.org/10.1007/978-94-007-5628-1_31openalex-snapshot
Capsicum frutescens
inferred← citeshttps://doi.org/10.1007/978-94-007-6317-3_1openalex-snapshot
Role of Capsaicin in Cancer Prevention
inferred← citeshttps://doi.org/10.1007/978-94-007-6317-3_2openalex-snapshot
Role of Death Receptors Belonging to the TNF Family in Capsaicin-Induced Apoptosis of Tumor Cells
inferred← citeshttps://doi.org/10.1007/978-94-007-6317-3_4openalex-snapshot
Capsaicin and the Urinary Bladder
inferred← citeshttps://doi.org/10.1007/978-94-007-6317-3_5openalex-snapshot
Inhibition of Pancreatitis and Carcinogenesis by Capsaicin
inferred← citeshttps://doi.org/10.1007/978-981-15-2361-8_14openalex-snapshot
Capsaicin and Its Potential Anticancer Mechanisms of Action
inferred← citeshttps://doi.org/10.1007/978-981-15-2361-8_15openalex-snapshot
Biosynthesis, Genetic Regulation and Therapeutic Potential of Capsaicinoids
inferred← citeshttps://doi.org/10.1007/978-981-15-5917-4_16openalex-snapshot
Capsicum chinense Jacq.: Ethnobotany, Bioactivity and Future Prospects
inferred← citeshttps://doi.org/10.1007/978-981-16-2210-6_53openalex-snapshot
Tourism, Health Promoting Food Domain and Technology Applications: Individual’s Genes Reservoir, Environmental Change and Food in Natural Health Context
inferred← citeshttps://doi.org/10.1007/978-981-19-3728-6_27openalex-snapshot
Capsicums and Chilies: An Introduction
inferred← citeshttps://doi.org/10.1007/978-981-99-7779-6_15openalex-snapshot
Pharmacological Applications of Capsaicin in the Treatment of Diseases
inferred← citeshttps://doi.org/10.1007/978-981-99-7779-6_16openalex-snapshot
Clinical Pharmacology of Capsaicin, Its Synthetic and Semisynthetic Analogues
inferred← citeshttps://doi.org/10.1007/978-981-99-7779-6_20openalex-snapshot
Exploring the Potential of Capsaicin in Cancer Therapy: In Vitro and In Vivo Effects and Their Mechanism of Action
inferred← citeshttps://doi.org/10.1007/978-981-99-7779-6_8openalex-snapshot
Biotechnological Approaches for Enhanced Production of Capsaicin
inferred← citeshttps://doi.org/10.1007/s10495-014-1007-yopenalex-snapshot
Capsaicin induces apoptosis in human small cell lung cancer via the TRPV6 receptor and the calpain pathway
inferred← citeshttps://doi.org/10.1007/s10571-015-0254-yopenalex-snapshot
Role of Autophagy in Capsaicin-Induced Apoptosis in U251 Glioma Cells
inferred← citeshttps://doi.org/10.1007/s10637-012-9849-zopenalex-snapshot
Tumor regression with a combination of drugs interfering with the tumor metabolism: efficacy of hydroxycitrate, lipoic acid and capsaicin
inferred← citeshttps://doi.org/10.1007/s11101-024-09957-5openalex-snapshot
Medicinal plants cultivated in Egypt with anticancer potential; a systematic review
inferred← citeshttps://doi.org/10.1007/s11523-014-0339-4openalex-snapshot
Targeting epidermal growth factor receptors and downstream signaling pathways in cancer by phytochemicals
inferred← citeshttps://doi.org/10.1007/s12328-011-0227-8openalex-snapshot
Chemoprevention against hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1007/s13277-015-3441-zopenalex-snapshot
RPF151, a novel capsaicin-like analogue: in vitro studies and in vivo preclinical antitumor evaluation in a breast cancer model
inferred← citeshttps://doi.org/10.1007/s40203-026-00753-xopenalex-snapshot
Bioinformatics-based identification of capsaicin target genes associated with trastuzumab resistance in HER2-positive breast cancer: in silico and qRT-PCR validation studies
inferred← citeshttps://doi.org/10.1016/b978-0-12-804305-9.00004-xopenalex-snapshot
Potential of nanotechnology in nutraceuticals delivery for the prevention and treatment of cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-819666-3.00002-xopenalex-snapshot
Natural product–based nanomedicine: polymeric nanoparticles as delivery cargoes of food bioactives and nutraceuticals for anticancer purposes
inferred← citeshttps://doi.org/10.1016/b978-0-12-821710-8.00013-8openalex-snapshot
Spice up your food for cancer prevention: Cancer chemo-prevention by natural compounds from common dietary spices
inferred← citeshttps://doi.org/10.1016/bs.acr.2024.05.005openalex-snapshot
Anti-cancer activity of capsaicin and its analogs in gynecological cancers
inferred← citeshttps://doi.org/10.1016/bs.pmbts.2017.07.008openalex-snapshot
Complementary and Alternative Medicine and Breast Cancer
inferred← citeshttps://doi.org/10.1016/j.ab.2017.07.023openalex-snapshot
Electrochemical detection of interaction between capsaicin and nucleic acids in comparison to agarose gel electrophoresis
inferred← citeshttps://doi.org/10.1016/j.bcp.2025.116828openalex-snapshot
Potential of capsaicin as a combinatorial agent to overcome chemoresistance and to improve outcomes of cancer therapy
inferred← citeshttps://doi.org/10.1016/j.bioorg.2020.104518openalex-snapshot
Synthesis of N-2(5H)-furanonyl sulfonyl hydrazone derivatives and their biological evaluation in vitro and in vivo activity against MCF-7 breast cancer cells
inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.105031openalex-snapshot
1,3,4-oxadiazole conjugates of capsaicin as potent NorA efflux pump inhibitors of Staphylococcus aureus
inferred← citeshttps://doi.org/10.1016/j.biopha.2017.07.075openalex-snapshot
Regulation of microRNA using promising dietary phytochemicals: Possible preventive and treatment option of malignant mesothelioma
inferred← citeshttps://doi.org/10.1016/j.biopha.2017.11.124openalex-snapshot
Research progress of capsaicin responses to various pharmacological challenges
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.113760openalex-snapshot
Phytotherapeutic applications of alkaloids in treating breast cancer
inferred← citeshttps://doi.org/10.1016/j.bmc.2018.04.031openalex-snapshot
Design, synthesis and biological evaluation of novel hydrogen sulfide releasing capsaicin derivatives
inferred← citeshttps://doi.org/10.1016/j.canlet.2023.216079openalex-snapshot
Prognostic significance of natural products against multidrug tumor resistance
inferred← citeshttps://doi.org/10.1016/j.cbi.2022.110043openalex-snapshot
Capsaicin inhibits the migration, invasion and EMT of renal cancer cells by inducing AMPK/mTOR-mediated autophagy
inferred← citeshttps://doi.org/10.1016/j.cpt.2024.07.003openalex-snapshot
Spices and culinary herbs for the prevention and treatment of breast cancer: A comprehensive review with mechanistic insights
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2016.02.008openalex-snapshot
Endocrine therapy in post-menopausal women with metastatic breast cancer: From literature and guidelines to clinical practice
inferred← citeshttps://doi.org/10.1016/j.cyto.2011.03.010openalex-snapshot
The vanilloid capsaicin induces IL-6 secretion in prostate PC-3 cancer cells
inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.111579openalex-snapshot
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile
inferred← citeshttps://doi.org/10.1016/j.ejphar.2010.09.074openalex-snapshot
Recent advances in the study on capsaicinoids and capsinoids
inferred← citeshttps://doi.org/10.1016/j.ejphar.2018.03.007openalex-snapshot
Potential phytocompounds for developing breast cancer therapeutics: Nature’s healing touch
inferred← citeshttps://doi.org/10.1016/j.eti.2017.02.006openalex-snapshot
Capsaicinoids are silent estrogens, a class of estrogenic chemicals without cell-proliferation activity
inferred← citeshttps://doi.org/10.1016/j.hermed.2024.100882openalex-snapshot
Capsaicin Ameliorates Chemotherapy Response via Cancer Hallmarks Modulation: An Overview of its Synergic Potential
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2019.12.058openalex-snapshot
Incorporation of Zataria multiflora essential oil into chitosan biopolymer nanoparticles: A nanoemulsion based delivery system to improve the in-vitro efficacy, stability and anticancer activity of ZEO against breast cancer cells
inferred← citeshttps://doi.org/10.1016/j.jconrel.2014.09.027openalex-snapshot
Bioavailability of capsaicin and its implications for drug delivery
inferred← citeshttps://doi.org/10.1016/j.jep.2018.08.019openalex-snapshot
Hepatoprotective effects of green Capsicum annum against ethanol induced oxidative stress, inflammation and apoptosis in rats
inferred← citeshttps://doi.org/10.1016/j.jff.2016.11.008openalex-snapshot
Use of potential dietary phytochemicals to target miRNA: Promising option for breast cancer prevention and treatment?
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2010.09.008openalex-snapshot
Bidirectional signaling of mammary epithelium and stroma: implications for breast cancer—preventive actions of dietary factors
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2011.03.009openalex-snapshot
Capsaicin represses transcriptional activity of β-catenin in human colorectal cancer cells
inferred← citeshttps://doi.org/10.1016/j.jorganchem.2013.05.033openalex-snapshot
Organotin polymers as anticancer and antiviral agents
inferred← citeshttps://doi.org/10.1016/j.mehy.2016.10.017openalex-snapshot
Chemosensitization role of fulvestrant in combination with chemotherapy in postmenopausal hormone receptor positive and human epidermal growth factor negative metastatic breast cancer
inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.140326openalex-snapshot
Capsaicinoids and cytotoxic activity in Capsicum annuum var. conoides
inferred← citeshttps://doi.org/10.1016/j.mrgentox.2015.02.003openalex-snapshot
Capsaicin-induced genotoxic stress does not promote apoptosis in A549 human lung and DU145 prostate cancer cells
inferred← citeshttps://doi.org/10.1016/j.phrs.2020.105164openalex-snapshot
Natural tyrosine kinase inhibitors acting on the epidermal growth factor receptor: Their relevance for cancer therapy
inferred← citeshttps://doi.org/10.1016/j.phrs.2021.105566openalex-snapshot
Capsaicin on stem cell proliferation and fate determination - a novel perspective
inferred← citeshttps://doi.org/10.1016/j.phymed.2020.153227openalex-snapshot
Breast Tumor Microenvironment: Emerging target of therapeutic phytochemicals
inferred← citeshttps://doi.org/10.1016/j.rechem.2024.101493openalex-snapshot
Synthesis and evaluation of the biological properties of boron-containing and boron-omitted capsaicin derivatives on human cancer cell lines
inferred← citeshttps://doi.org/10.1016/j.semcancer.2017.07.002openalex-snapshot
Regulation of cell signaling pathways by dietary agents for cancer prevention and treatment
inferred← citeshttps://doi.org/10.1016/j.semcancer.2019.12.010openalex-snapshot
Repurposing of plant alkaloids for cancer therapy: Pharmacology and toxicology
inferred← citeshttps://doi.org/10.1016/j.taap.2012.11.029openalex-snapshot
RPF101, a new capsaicin-like analogue, disrupts the microtubule network accompanied by arrest in the G2/M phase, inducing apoptosis and mitotic catastrophe in the MCF-7 breast cancer cells
inferred← citeshttps://doi.org/10.1016/j.taap.2018.09.025openalex-snapshot
TRPV1 mediates capsaicin-stimulated metabolic activity but not cell death or inhibition of interleukin-1β release in human THP-1 monocytes
inferred← citeshttps://doi.org/10.1016/j.toxlet.2014.04.007openalex-snapshot
An exploration of the estrogen receptor transcription activity of capsaicin analogues via an integrated approach based on in silico prediction and in vitro assays
inferred← citeshttps://doi.org/10.1016/j.yexcr.2019.04.007openalex-snapshot
Targeting the unfolded protein response in head and neck and oral cavity cancers
inferred← citeshttps://doi.org/10.1017/s0021859615000714openalex-snapshot
Effects of arbuscular mycorrhizal fungi onCapsicumspp.
inferred← citeshttps://doi.org/10.1021/acs.jafc.6b01095openalex-snapshot
Development of Organogel-Derived Capsaicin Nanoemulsion with Improved Bioaccessibility and Reduced Gastric Mucosa Irritation
inferred← citeshttps://doi.org/10.1021/acs.jafc.9b04016openalex-snapshot
Capsaicin Ameliorates the Redox Imbalance and Glucose Metabolism Disorder in an Insulin-Resistance Model via Circadian Clock-Related Mechanisms
inferred← citeshttps://doi.org/10.1021/acs.nanolett.7b05292openalex-snapshot
Semiconducting Photothermal Nanoagonist for Remote-Controlled Specific Cancer Therapy
inferred← citeshttps://doi.org/10.1021/acsmedchemlett.1c00304openalex-snapshot
Apoptosis Inducing 1,3,4-Oxadiazole Conjugates of Capsaicin: Their In Vitro Antiproliferative and In Silico Studies
inferred← citeshttps://doi.org/10.1021/je1011136openalex-snapshot
Measurement and Correlation for the Solubilities of Dihydrocapsaicin inn-Heptane,n-Hexane,n-Pentane, Ethyl Acetate, Acetone, Ethanol, and Water
inferred← citeshttps://doi.org/10.1038/s41417-023-00690-3openalex-snapshot
Arvanil induces ferroptosis of hepatocellular carcinoma by binding to MICU1
inferred← citeshttps://doi.org/10.1038/s41598-023-40933-9openalex-snapshot
Capsaicin binds the N-terminus of Hsp90, induces lysosomal degradation of Hsp70, and enhances the anti-tumor effects of 17-AAG (Tanespimycin)
inferred← citeshttps://doi.org/10.1039/c4an01834fopenalex-snapshot
High throughput absorbance spectra of cancerous cells: a microscopic investigation of spectral artifacts
inferred← citeshttps://doi.org/10.1039/c5cs00916bopenalex-snapshot
Natural product modulators of transient receptor potential (TRP) channels as potential anti-cancer agents
inferred← citeshttps://doi.org/10.1039/d4nr04454aopenalex-snapshot
Capsaicin-induced Ca 2+ overload and ablation of TRPV1-expressing axonal terminals for comfortable tumor immunotherapy
inferred← citeshttps://doi.org/10.1055/a-2309-5581openalex-snapshot
A Comprehensive Review of Capsaicin and Its Role in Cancer Prevention and Treatment
inferred← citeshttps://doi.org/10.1080/01635581.2011.523497openalex-snapshot
Tumor Cell Growth Inhibition Is Correlated With Levels of Capsaicin Present in Hot Peppers
inferred← citeshttps://doi.org/10.1080/01635581.2012.630551openalex-snapshot
Cancer Cell Signaling Pathways Targeted by Spice-Derived Nutraceuticals
inferred← citeshttps://doi.org/10.1080/07352689.2019.1682791openalex-snapshot
The Hot and the Colorful: Understanding the Metabolism, Genetics and Evolution of Consumer Preferred Metabolic Traits in Pepper and Related Species
inferred← citeshttps://doi.org/10.1080/10408398.2020.1855413openalex-snapshot
The potential role of dietary plant ingredients against mammary cancer: a comprehensive review
inferred← citeshttps://doi.org/10.1080/10408398.2021.1884840openalex-snapshot
Extraction, purification, bioactivity and pharmacological effects of capsaicin: a review
inferred← citeshttps://doi.org/10.1080/13102818.2020.1749527openalex-snapshot
Medicinal plants with anti-mutagenic potential
inferred← citeshttps://doi.org/10.1080/14786419.2023.2251167openalex-snapshot
Antitumor and chemopreventive role of major phytochemicals against breast cancer development
inferred← citeshttps://doi.org/10.1080/15287394.2010.511572openalex-snapshot
Capsaicin Impairs Proliferation of Neural Progenitor Cells and Hippocampal Neurogenesis in Young Mice
inferred← citeshttps://doi.org/10.1080/15384047.2016.1235654openalex-snapshot
Capsaicin reactivates hMOF in gastric cancer cells and induces cell growth inhibition
inferred← citeshttps://doi.org/10.1088/1361-6528/abc57eopenalex-snapshot
Capsaicin-loaded solid lipid nanoparticles: design, biodistribution, in silico modeling and in vitro cytotoxicity evaluation
inferred← citeshttps://doi.org/10.1089/cbr.2017.2186openalex-snapshot
Development of 68 Ga-SCN-DOTA-Capsaicin as an Imaging Agent Targeting Apoptosis and Cell Cycle Arrest in Breast Cancer
inferred← citeshttps://doi.org/10.1093/carcin/bgae032openalex-snapshot
Capsaicin enhances cisplatin-induced anti-metastasis of nasopharyngeal carcinoma by inhibiting EMT and ERK signaling via serpin family B member 2
inferred← citeshttps://doi.org/10.1093/carcin/bgr191openalex-snapshot
Inhibition of chronic pancreatitis and pancreatic intraepithelial neoplasia (PanIN) by capsaicin in LSL-KrasG12D/Pdx1-Cre mice
inferred← citeshttps://doi.org/10.1093/jjco/hyad194openalex-snapshot
Transient receptor potential cation channel subfamily V member 1 (TRPV1) targeted PET imaging
inferred← citeshttps://doi.org/10.1093/toxsci/kfs163openalex-snapshot
Phthalates Stimulate the Epithelial to Mesenchymal TransitionThrough an HDAC6-Dependent Mechanism in Human BreastEpithelial Stem Cells
inferred← citeshttps://doi.org/10.1097/nt.0b013e3182076ff2openalex-snapshot
Red Pepper
inferred← citeshttps://doi.org/10.1111/1759-7714.14834openalex-snapshot
Sauchinone inhibits breast cancer cell proliferation through regulating microRNA ‐148a‐3p/ HER ‐2 axis
inferred← citeshttps://doi.org/10.1111/jcpt.13039openalex-snapshot
Application of capsaicin as a potential new therapeutic drug in human cancers
inferred← citeshttps://doi.org/10.1124/jpet.111.188706openalex-snapshot
Blocking Epidermal Growth Factor Receptor Activation by 3,3′-Diindolylmethane Suppresses Ovarian Tumor Growth In Vitro and In Vivo
inferred← citeshttps://doi.org/10.1155/2019/9051542openalex-snapshot
ROS-Mediated Cancer Cell Killing through Dietary Phytochemicals
inferred← citeshttps://doi.org/10.11606/d.9.2014.tde-28042014-145554openalex-snapshot
Planejamento e síntese de análogos da capsaicina e avaliação da atividade antitumoral
inferred← citeshttps://doi.org/10.11606/d.9.2014.tde-29102014-153643openalex-snapshot
Candidatos a novos agentes antineoplásicos: síntese e avaliação da atividade antitumoral de análogos sulfonatos e sulfonamídicos da capsaicina
inferred← citeshttps://doi.org/10.11606/d.9.2019.tde-11032019-113728openalex-snapshot
Potenciais candidatos a novos agentes antineoplásicos: síntese e avaliação da atividade antitumoral de análogos ureídicos e tioureidicos da capsaicina
inferred← citeshttps://doi.org/10.1177/0192623312444471openalex-snapshot
A Comprehensive Review of the Carcinogenic and Anticarcinogenic Potential of Capsaicin
inferred← citeshttps://doi.org/10.1177/1087057114549147openalex-snapshot
Progesterone Receptor Chaperone Complex–Based High-Throughput Screening Assay: Identification of Capsaicin as an Inhibitor of the Hsp90 Machine
inferred← citeshttps://doi.org/10.1179/1351000214y.0000000113openalex-snapshot
Oxidant-based anticancer activity of a novel synthetic analogue of capsaicin, capsaicin epoxide
inferred← citeshttps://doi.org/10.1186/1472-6882-13-46openalex-snapshot
Capsaicin induces cell cycle arrest and apoptosis in human KB cancer cells
inferred← citeshttps://doi.org/10.1186/s41544-019-0017-xopenalex-snapshot
Co-targeting of EGFR by co-expressed miRNA-193a-3p/−5p in lung cancer
inferred← citeshttps://doi.org/10.13040/ijpsr.0975-8232.7(3).882-89openalex-snapshot
inferred← citeshttps://doi.org/10.1371/journal.pone.0010243openalex-snapshot
Capsaicin Displays Anti-Proliferative Activity against Human Small Cell Lung Cancer in Cell Culture and Nude Mice Models via the E2F Pathway
inferred← citeshttps://doi.org/10.1371/journal.pone.0020151openalex-snapshot
Role of Mitochondrial Electron Transport Chain Complexes in Capsaicin Mediated Oxidative Stress Leading to Apoptosis in Pancreatic Cancer Cells
inferred← citeshttps://doi.org/10.1371/journal.pone.0043577openalex-snapshot
Inhibition of EGFR-AKT Axis Results in the Suppression of Ovarian Tumors In Vitro and in Preclinical Mouse Model
inferred← citeshttps://doi.org/10.1371/journal.pone.0099743openalex-snapshot
Capsaicin-Induced Activation of p53-SMAR1 Auto-Regulatory Loop Down-Regulates VEGF in Non-Small Cell Lung Cancer to Restrain Angiogenesis
inferred← citeshttps://doi.org/10.1371/journal.pone.0350841openalex-snapshot
Identification of potential key genes that respond to capsaicin treatment in ER-positive breast cancer: An integrated analysis
inferred← citeshttps://doi.org/10.14715/cmb/2020.66.6.18openalex-snapshot
Lowered Cyclin E levels increase the efficiency and the specificity of capsaicin against cancerous cells of mesothelium
inferred← citeshttps://doi.org/10.14744/ejmi.2020.17680openalex-snapshot
Effects of Fenugreek Extract on Total Antioxidant/Oxidant Status at Ehrlich Ascites Tumor Bearing Mice
inferred← citeshttps://doi.org/10.15430/jcp.2014.19.4.253openalex-snapshot
Cancer Preventive Potential of Kimchi Lactic Acid Bacteria (Weissella cibaria, Lactobacillus plantarum)
inferred← citeshttps://doi.org/10.15430/jcp.2015.20.4.223openalex-snapshot
Natural Products for Chemoprevention of Breast Cancer
inferred← citeshttps://doi.org/10.17756/jfcn.2016-025openalex-snapshot
Anti-Tumorigenic Effects of Capsaicin in Colon Cancer
inferred← citeshttps://doi.org/10.2147/dddt.s269901openalex-snapshot
Capsaicin Inhibits Proliferation and Induces Apoptosis in Breast Cancer by Down-Regulating FBI-1-Mediated NF-κB Pathway
inferred← citeshttps://doi.org/10.2174/0109298673310050240821054652openalex-snapshot
Natural and Synthetic Capsaicin Analogues: A Comprehensive Review of Biological Effects and Synthetic Pathways
inferred← citeshttps://doi.org/10.2174/0115680266275768231027100120openalex-snapshot
Natural Plant Products Mediated Prevention of Cancer Facilitated through Immune Suppression of Treg Cells
inferred← citeshttps://doi.org/10.2174/0115734072331654241211032635openalex-snapshot
Therapeutic Potential of Alkaloids to Combat Breast Cancer: A Mechanistic Overview
inferred← citeshttps://doi.org/10.2174/011874091x328840250131070747openalex-snapshot
The Apoptotic and Antioxidant Effects of Capsaicin on Colorectal Cancer Cell Lines
inferred← citeshttps://doi.org/10.2174/1386207325666220726164712openalex-snapshot
Naturally Occurring Compounds as Potential Inhibitors of Epidermal Growth Factor Receptors (EGFRs)
inferred← citeshttps://doi.org/10.2174/1568009615666141229152256openalex-snapshot
Phytochemicals for Breast Cancer Therapy: Current Status and Future Implications
inferred← citeshttps://doi.org/10.2174/15680266113139990150openalex-snapshot
Mitochondria: A Promising Target for Anticancer Alkaloids
inferred← citeshttps://doi.org/10.2174/1573394715666181129101502openalex-snapshot
Recent Advances of Novel Therapeutic Agents from Botanicals for Prevention and Therapy of Breast Cancer: An Updated Review
inferred← citeshttps://doi.org/10.22159/ajpcr.2018.v11i6.24322openalex-snapshot
MALAYSIAN MEDICINAL PLANTS’ POTENTIAL FOR BREAST CANCER THERAPY
inferred← citeshttps://doi.org/10.22159/ajpcr.2022.v15i7.44405openalex-snapshot
THERAPEUTIC PROPERTIES OF CAPSAICIN: A MEDICINALLY IMPORTANT BIO-ACTIVE CONSTITUENT OF CHILLI PEPPER
inferred← citeshttps://doi.org/10.25004/ijpsdr.2011.030402openalex-snapshot
AN OVERVIEW ABOUT VERSATILE MOLECULE CAPSAICIN
inferred← citeshttps://doi.org/10.25258/ijddt.v5i2.8869openalex-snapshot
Evaluation of Biocompatibility of Capsaicin-Loaded Dendrimers on Zebrafish Embryos
inferred← citeshttps://doi.org/10.2527/jas.2013-6496openalex-snapshot
Effects of capsicum oleoresin, garlic botanical, and turmeric oleoresin on gene expression profile of ileal mucosa in weaned pigs1
inferred← citeshttps://doi.org/10.25959/23205209openalex-snapshot
The Effects of vanilloid-like agents on platelet aggregation
inferred← citeshttps://doi.org/10.30564/jor.v3i2.3649openalex-snapshot
Paracelsus Paradox and Drug Repurposing for Cancer
inferred← citeshttps://doi.org/10.3109/10715762.2016.1173689openalex-snapshot
Inhibiting ROS-STAT3-dependent autophagy enhanced capsaicin–induced apoptosis in human hepatocellular carcinoma cells
inferred← citeshttps://doi.org/10.33808/clinexphealthsci.1218885openalex-snapshot
The Relationship Between Capsaicin in Chili Pepper and Cancer: A Comprehensive Insight
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1277243openalex-snapshot
Harnessing the power of traditional Chinese medicine monomers and compound prescriptions to boost cancer immunotherapy
inferred← citeshttps://doi.org/10.3389/fonc.2019.00083openalex-snapshot
Capsaicin Induces Apoptosis in KSHV-Positive Primary Effusion Lymphoma by Suppressing ERK and p38 MAPK Signaling and IL-6 Expression
inferred← citeshttps://doi.org/10.3389/fphar.2022.989575openalex-snapshot
A state-of-the-art review on LSD1 and its inhibitors in breast cancer: Molecular mechanisms and therapeutic significance
inferred← citeshttps://doi.org/10.3389/fphys.2021.715469openalex-snapshot
Capsaicin Attenuates Lipopolysaccharide-Induced Inflammation and Barrier Dysfunction in Intestinal Porcine Epithelial Cell Line-J2
inferred← citeshttps://doi.org/10.3389/fpls.2026.1823752openalex-snapshot
Spicy genes: mapping quantitative genomic regions and candidate genes for capsaicinoid and capsinoid biosynthesis in pepper
inferred← citeshttps://doi.org/10.3390/agriculture11020181openalex-snapshot
Fertilization Management Improves the Yield and Capsaicinoid Content of Chili Peppers
inferred← citeshttps://doi.org/10.3390/biology14020194openalex-snapshot
Modulation of Wnt/Beta-Catenin Pathway by Major Dietary Phytochemicals Against Breast Cancer Development
inferred← citeshttps://doi.org/10.3390/cancers10100346openalex-snapshot
The “Yin and Yang” of Natural Compounds in Anticancer Therapy of Triple-Negative Breast Cancers
inferred← citeshttps://doi.org/10.3390/cells8101275openalex-snapshot
Capsaicin Targets tNOX (ENOX2) to Inhibit G1 Cyclin/CDK Complex, as Assessed by the Cellular Thermal Shift Assay (CETSA)
inferred← citeshttps://doi.org/10.3390/cimb47070498openalex-snapshot
The Role of Plant-Derived Natural Products as a Regulator of the Tyrosine Kinase Pathway in the Management of Lung Cancer
inferred← citeshttps://doi.org/10.3390/ijms18071343openalex-snapshot
Capsaicin Induces Autophagy and Apoptosis in Human Nasopharyngeal Carcinoma Cells by Downregulating the PI3K/AKT/mTOR Pathway
inferred← citeshttps://doi.org/10.3390/ijms232214152openalex-snapshot
Phytochemical Targeting of Mitochondria for Breast Cancer Chemoprevention, Therapy, and Sensitization
inferred← citeshttps://doi.org/10.3390/ijms26115257openalex-snapshot
Lysine Acetyltransferase 8: A Target for Natural Compounds in Cancer Therapy
inferred← citeshttps://doi.org/10.3390/ijms262412079openalex-snapshot
A Narrative Review on the Antitumoral Effects of Selected Mediterranean Plant Products from Southern Italy
inferred← citeshttps://doi.org/10.3390/ijms27198435openalex-snapshot
Capsaicin Induces G2/M Cell-Cycle Arrest and Impairs Autophagy in Caco-2 Cells: An Exploratory Study
inferred← citeshttps://doi.org/10.3390/molecules21070844openalex-snapshot
Capsaicin: Current Understanding of Its Mechanisms and Therapy of Pain and Other Pre-Clinical and Clinical Uses
inferred← citeshttps://doi.org/10.3390/molecules21080931openalex-snapshot
Capsaicin: From Plants to a Cancer-Suppressing Agent
inferred← citeshttps://doi.org/10.3390/molecules21080966openalex-snapshot
Harnessing the Therapeutic Potential of Capsaicin and Its Analogues in Pain and Other Diseases
inferred← citeshttps://doi.org/10.3390/molecules26061521openalex-snapshot
Peppers: A “Hot” Natural Source for Antitumor Compounds
inferred← citeshttps://doi.org/10.3390/molecules27092669openalex-snapshot
Cannabis sativa CBD Extract Shows Promising Antibacterial Activity against Salmonella typhimurium and S. newington
inferred← citeshttps://doi.org/10.3390/nano12173075openalex-snapshot
Curcumin and Capsaicin-Loaded Ag-Modified Mesoporous Silica Carriers: A New Alternative in Skin Treatment
inferred← citeshttps://doi.org/10.3390/nu12113537openalex-snapshot
The Potential Role of Nutraceuticals as an Adjuvant in Breast Cancer Patients to Prevent Hair Loss Induced by Endocrine Therapy
inferred← citeshttps://doi.org/10.3390/nu16213758openalex-snapshot
Capsaicin Exerts Antitumor Activity in Mesothelioma Cells
inferred← citeshttps://doi.org/10.3390/nu8030156openalex-snapshot
Dietary Natural Products for Prevention and Treatment of Liver Cancer
inferred← citeshttps://doi.org/10.3390/nu8080495openalex-snapshot
Spices for Prevention and Treatment of Cancers
inferred← citeshttps://doi.org/10.3390/nu9070728openalex-snapshot
Dietary Natural Products for Prevention and Treatment of Breast Cancer
inferred← citeshttps://doi.org/10.36468/pharmaceutical-sciences.598openalex-snapshot
Development and Characterization of a Phospholipid Complex for Effective Delivery of Capsaicin
inferred← citeshttps://doi.org/10.3724/abbs.2024068openalex-snapshot
Function and mechanism of action of the TRPV1 channel in the development of triple-negative breast cancer
inferred← citeshttps://doi.org/10.3892/mmr.2013.1849openalex-snapshot
Capsaicin induces apoptosis and modulates MAPK signaling in human gastric cancer cells
inferred← citeshttps://doi.org/10.3892/mmr.2016.5784openalex-snapshot
Capsaicin and dihydrocapsaicin induce apoptosis in human glioma cells via ROS and Ca2+-mediated mitochondrial pathway
inferred← citeshttps://doi.org/10.3892/or.2017.5960openalex-snapshot
Capsaicin inhibits proliferation and induces apoptosis in osteosarcoma cell lines via the mitogen-activated protein kinase pathway
inferred← citeshttps://doi.org/10.3906/biy-1409-60openalex-snapshot
Histone deacetylase inhibitory activity of hydroxycapsaicin, a synthetic derivative of capsaicin, and its cytotoxic effects against human colon cancer cell lines
inferred← citeshttps://doi.org/10.4103/2221-1691.290133openalex-snapshot
In vitro antioxidant and anti-cancer activities and phytochemical analysis of Commelina benghalensis L. root extracts
inferred← citeshttps://doi.org/10.4155/fmc.13.46openalex-snapshot
Hot Peppers for a Healthier Future: Boron-Containing Capsaicinoids
inferred← citeshttps://doi.org/10.4172/2167-0501.1000205openalex-snapshot
Phytochemical Screening, Antioxidant Activities and In Vitro Anticancer Potential of Egyptian Capsicum Spp.
inferred← citeshttps://doi.org/10.46332/aemj.1592791openalex-snapshot
Kapsaisin Endoplazmik Stres Yoluyla Endometrial Kanser Hücrelerinde Apoptozu İndükler ve Antiproliferatif Etkileri Tetikler
inferred← citeshttps://doi.org/10.48175/ijarsct-18301openalex-snapshot
Formulation and Evaluation of Logenzes for Anticoagulantion
inferred← citeshttps://doi.org/10.5101/nbe.v13i4.p433-445openalex-snapshot
Capsaicin Nanoparticles as Therapeutic Agents against Gliomas
inferred← citeshttps://doi.org/10.52711/0974-360x.2021.00653openalex-snapshot
Phytochemical analysis, Antimicrobial and Antioxidant assay of Bhut Jolokia pepper
inferred← citeshttps://doi.org/10.53811/ijtcmr.1433242openalex-snapshot
Investigation of Antitumor Activity of Fenugreek Paste Extracts
inferred← citeshttps://doi.org/10.5772/24833openalex-snapshot
Ionic Channels in the Therapy of Malignant Glioma
inferred← citeshttps://doi.org/10.5772/intechopen.104906openalex-snapshot
Pharmacological Properties and Health Benefits of Capsicum Species: A Comprehensive Review
inferred← citeshttps://doi.org/10.5772/intechopen.98137openalex-snapshot
Capsicum - Current Trends and Perspectives
inferred← citeshttps://doi.org/10.5958/0974-4479.2021.00017.4openalex-snapshot
Ghost Pepper (Capsicum chinense Jacq.) - A Reservoir Plant for Therapeutic Applications: An Overview
inferred← citeshttps://doi.org/10.64898/2026.05.27.728130openalex-snapshot
Differential Induction of Cancer Cell Death by Root, Leaf, and Flower Extract derived from Kalanchoe pinnata
inferred← citeshttps://doi.org/10.7150/thno.45191openalex-snapshot
Therapeutic potential of targeting MKK3-p38 axis with Capsaicin for Nasopharyngeal Carcinoma
inferred← citeshttps://doi.org/10.7324/japs.2024.175359openalex-snapshot
A review on phytochemical and pharmacological potential of Bhut Jolokia (a cultivar of Capsicum chinense Jacq.)
inferred← citeshttps://doi.org/10.83056/mmu.32479050openalex-snapshot
Capsaicinoids – a potential role for weight management
inferred← citeshttps://doi.org/10.9734/jcti/2023/v13i3235openalex-snapshot
Breast Cancer: Classification, Risk Factors, Current Diagnostic Procedures and Therapeutics
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