On the public citation graph
Senescence and aging: the critical roles of p53
0 signed · 1074 inferred · view as graph
Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/s00018-008-8119-xopenalex-snapshot
p63 in epithelial development
inferredcites →https://doi.org/10.1007/s12035-011-8172-6openalex-snapshot
p73: A Multifunctional Protein in Neurobiology
inferredcites →https://doi.org/10.1016/0014-4827(65)90211-9openalex-snapshot
The limited in vitro lifetime of human diploid cell strains
inferredcites →https://doi.org/10.1016/j.bbrc.2005.03.156openalex-snapshot
p73 induces apoptosis by different mechanisms
inferredcites →https://doi.org/10.1016/j.ccr.2005.02.019openalex-snapshot
Tumor predisposition in mice mutant for p63 and p73: Evidence for broader tumor suppressor functions for the p53 family
inferredcites →https://doi.org/10.1016/j.ccr.2006.06.001openalex-snapshot
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
inferredcites →https://doi.org/10.1016/j.ccr.2007.02.026openalex-snapshot
Short Telomeres Limit Tumor Progression In Vivo by Inducing Senescence
inferredcites →https://doi.org/10.1016/j.ccr.2008.06.002openalex-snapshot
A Prostatic Intraepithelial Neoplasia-Dependent p27Kip1 Checkpoint Induces Senescence and Inhibits Cell Proliferation and Cancer Progression
inferredcites →https://doi.org/10.1016/j.ccr.2008.09.001openalex-snapshot
Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice
inferredcites →https://doi.org/10.1016/j.ccr.2011.12.020openalex-snapshot
Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib
inferredcites →https://doi.org/10.1016/j.ceb.2009.12.001openalex-snapshot
Autophagy regulation by p53
inferredcites →https://doi.org/10.1016/j.cell.2005.02.001openalex-snapshot
Mitochondria, Oxidants, and Aging
inferredcites →https://doi.org/10.1016/j.cell.2005.02.003openalex-snapshot
Senescent Cells, Tumor Suppression, and Organismal Aging: Good Citizens, Bad Neighbors
inferredcites →https://doi.org/10.1016/j.cell.2006.11.050openalex-snapshot
PRAK Is Essential for ras-Induced Senescence and Tumor Suppression
inferredcites →https://doi.org/10.1016/j.cell.2007.02.045openalex-snapshot
p63 Is Essential for the Proliferative Potential of Stem Cells in Stratified Epithelia
inferredcites →https://doi.org/10.1016/j.cell.2008.06.028openalex-snapshot
p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
inferredcites →https://doi.org/10.1016/j.cell.2008.10.025openalex-snapshot
SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging
inferredcites →https://doi.org/10.1016/j.cell.2009.04.037openalex-snapshot
Blinded by the Light: The Growing Complexity of p53
inferredcites →https://doi.org/10.1016/j.cell.2009.07.034openalex-snapshot
4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila
inferredcites →https://doi.org/10.1016/j.cell.2011.02.013openalex-snapshot
Hallmarks of Cancer: The Next Generation
inferredcites →https://doi.org/10.1016/j.cell.2012.04.026openalex-snapshot
Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence
inferredcites →https://doi.org/10.1016/j.cmet.2008.08.014openalex-snapshot
SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice
inferredcites →https://doi.org/10.1016/j.cmet.2010.05.001openalex-snapshot
With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging
inferredcites →https://doi.org/10.1016/j.cmet.2010.11.004openalex-snapshot
Targeted Expression of Catalase to Mitochondria Prevents Age-Associated Reductions in Mitochondrial Function and Insulin Resistance
inferredcites →https://doi.org/10.1016/j.cmet.2010.11.007openalex-snapshot
Nuclear Receptor Corepressor SMRT Regulates Mitochondrial Oxidative Metabolism and Mediates Aging-Related Metabolic Deterioration
inferredcites →https://doi.org/10.1016/j.cmet.2012.09.006openalex-snapshot
TAp63 Is a Master Transcriptional Regulator of Lipid and Glucose Metabolism
inferredcites →https://doi.org/10.1016/j.cub.2004.03.059openalex-snapshot
Regulation of Lifespan in Drosophila by Modulation of Genes in the TOR Signaling Pathway
inferredcites →https://doi.org/10.1016/j.cub.2010.10.029openalex-snapshot
TAp73 Acts via the bHLH Hey2 to Promote Long-Term Maintenance of Neural Precursors
inferredcites →https://doi.org/10.1016/j.exger.2004.06.025openalex-snapshot
Ink4a/Arf links senescence and aging
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2008.11.008openalex-snapshot
The wanderings of a free radical
inferredcites →https://doi.org/10.1016/j.molcel.2007.06.036openalex-snapshot
p73 Suppresses Polyploidy and Aneuploidy in the Absence of Functional p53
inferredcites →https://doi.org/10.1016/j.neuron.2008.07.021openalex-snapshot
p73 Regulates Neurodegeneration and Phospho-Tau Accumulation during Aging and Alzheimer's Disease
inferredcites →https://doi.org/10.1016/j.semcancer.2008.11.005openalex-snapshot
Homeostatic functions of the p53 tumor suppressor: Regulation of energy metabolism and antioxidant defense
inferredcites →https://doi.org/10.1016/j.stem.2009.04.003openalex-snapshot
TAp63 Prevents Premature Aging by Promoting Adult Stem Cell Maintenance
inferredcites →https://doi.org/10.1016/j.stem.2010.12.009openalex-snapshot
ΔNp63α Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis
inferredcites →https://doi.org/10.1016/j.yexcr.2008.01.011openalex-snapshot
Free radicals and senescence
inferredcites →https://doi.org/10.1016/j.yjmcc.2007.08.008openalex-snapshot
Sirt1 modulates premature senescence-like phenotype in human endothelial cells
inferredcites →https://doi.org/10.1016/s0092-8674(00)80580-2openalex-snapshot
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
inferredcites →https://doi.org/10.1016/s0092-8674(00)80762-xopenalex-snapshot
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
inferredcites →https://doi.org/10.1016/s0092-8674(01)00524-4openalex-snapshot
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
inferredcites →https://doi.org/10.1016/s0092-8674(01)00527-xopenalex-snapshot
hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase
inferredcites →https://doi.org/10.1016/s0092-8674(01)80006-4openalex-snapshot
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
inferredcites →https://doi.org/10.1016/s0140-6736(89)92145-4openalex-snapshot
MITOCHONDRIAL DNA MUTATIONS AS AN IMPORTANT CONTRIBUTOR TO AGEING AND DEGENERATIVE DISEASES
inferredcites →https://doi.org/10.1016/s0959-8049(97)00062-2openalex-snapshot
A survey of telomerase activity in human cancer
inferredcites →https://doi.org/10.1016/s0960-9822(98)70137-xopenalex-snapshot
Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts
inferredcites →https://doi.org/10.1038/19531openalex-snapshot
p63 is a p53 homologue required for limb and epidermal morphogenesis
inferredcites →https://doi.org/10.1038/19539openalex-snapshot
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
inferredcites →https://doi.org/10.1038/21690openalex-snapshot
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
inferredcites →https://doi.org/10.1038/21697openalex-snapshot
Interaction of c-Abl and p73α and their collaboration to induce apoptosis
inferredcites →https://doi.org/10.1038/21704openalex-snapshot
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
inferredcites →https://doi.org/10.1038/33345openalex-snapshot
Essential role of mouse telomerase in highly proliferative organs
inferredcites →https://doi.org/10.1038/35003607openalex-snapshot
p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
inferredcites →https://doi.org/10.1038/35018127openalex-snapshot
PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
inferredcites →https://doi.org/10.1038/35065638openalex-snapshot
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
inferredcites →https://doi.org/10.1038/356215a0openalex-snapshot
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
inferredcites →https://doi.org/10.1038/377552a0openalex-snapshot
Radiation-induced cell cycle arrest compromised by p21 deficiency
inferredcites →https://doi.org/10.1038/cdd.2008.139openalex-snapshot
Autophagy in aging, disease and death: the true identity of a cell death impostor
inferredcites →https://doi.org/10.1038/cdd.2008.69openalex-snapshot
miR-203 represses ‘stemness’ by repressing ΔNp63
inferredcites →https://doi.org/10.1038/cdd.2010.101openalex-snapshot
SUMO-modified nuclear cyclin D1 bypasses Ras-induced senescence
inferredcites →https://doi.org/10.1038/cdd.2010.104openalex-snapshot
Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy
inferredcites →https://doi.org/10.1038/cdd.2010.106openalex-snapshot
A positive role for c-Abl in Atm and Atr activation in DNA damage response
inferredcites →https://doi.org/10.1038/cdd.2010.115openalex-snapshot
Negative regulation of autophagy
inferredcites →https://doi.org/10.1038/cdd.2010.131openalex-snapshot
p73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis
inferredcites →https://doi.org/10.1038/cdd.2010.132openalex-snapshot
c-Abl tyrosine kinase in the DNA damage response: cell death and more
inferredcites →https://doi.org/10.1038/cdd.2010.139openalex-snapshot
PTEN status switches cell fate between premature senescence and apoptosis in glioma exposed to ionizing radiation
inferredcites →https://doi.org/10.1038/cdd.2010.159openalex-snapshot
ΔNp63 is an ectodermal gatekeeper of epidermal morphogenesis
inferredcites →https://doi.org/10.1038/cdd.2010.164openalex-snapshot
MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival
inferredcites →https://doi.org/10.1038/cdd.2010.174openalex-snapshot
Therapeutic targets in cancer cell metabolism and death
inferredcites →https://doi.org/10.1038/cdd.2010.177openalex-snapshot
Mortalin–p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy
inferredcites →https://doi.org/10.1038/cdd.2010.178openalex-snapshot
p73 is critical for the persistence of memory
inferredcites →https://doi.org/10.1038/cdd.2010.191openalex-snapshot
The Beclin 1 network regulates autophagy and apoptosis
inferredcites →https://doi.org/10.1038/cdd.2010.35openalex-snapshot
p53-family proteins and their regulators: hubs and spokes in tumor suppression
inferredcites →https://doi.org/10.1038/cdd.2010.77openalex-snapshot
SIRT1 stabilizes PML promoting its sumoylation
inferredcites →https://doi.org/10.1038/cdd.2010.93openalex-snapshot
Specific disintegration of complex II succinate:ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction
inferredcites →https://doi.org/10.1038/cdd.2011.12openalex-snapshot
Roles of HAUSP-mediated p53 regulation in central nervous system development
inferredcites →https://doi.org/10.1038/cdd.2011.120openalex-snapshot
Biological functions of p53 isoforms through evolution: lessons from animal and cellular models
inferredcites →https://doi.org/10.1038/cdd.2011.143openalex-snapshot
A set of miRNAs participates in the cellular senescence program in human diploid fibroblasts
inferredcites →https://doi.org/10.1038/cdd.2011.173openalex-snapshot
MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs
inferredcites →https://doi.org/10.1038/cdd.2011.181openalex-snapshot
Regulation of skin aging and heart development by TAp63
inferredcites →https://doi.org/10.1038/cdd.2011.182openalex-snapshot
Chk2 mediates RITA-induced apoptosis
inferredcites →https://doi.org/10.1038/cdd.2011.33openalex-snapshot
Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death
inferredcites →https://doi.org/10.1038/cdd.2011.42openalex-snapshot
miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition
inferredcites →https://doi.org/10.1038/cdd.2011.43openalex-snapshot
Role of autophagy in disease resistance and hypersensitive response-associated cell death
inferredcites →https://doi.org/10.1038/cdd.2011.45openalex-snapshot
Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX
inferredcites →https://doi.org/10.1038/cdd.2011.57openalex-snapshot
E3 ubiquitin ligase Hades negatively regulates the exonuclear function of p53
inferredcites →https://doi.org/10.1038/cdd.2011.65openalex-snapshot
Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics, and neuronal synaptic damage in neurodegenerative diseases
inferredcites →https://doi.org/10.1038/cdd.2011.71openalex-snapshot
SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis
inferredcites →https://doi.org/10.1038/cdd.2011.73openalex-snapshot
ΔNp63α regulates keratinocyte proliferation by controlling PTEN expression and localization
inferredcites →https://doi.org/10.1038/cdd.2011.81openalex-snapshot
p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53
inferredcites →https://doi.org/10.1038/cdd.2012.102openalex-snapshot
The critical role of catalase in prooxidant and antioxidant function of p53
inferredcites →https://doi.org/10.1038/cdd.2012.113openalex-snapshot
Induction of autophagy and senescence by knockdown of ROC1 E3 ubiquitin ligase to suppress the growth of liver cancer cells
inferredcites →https://doi.org/10.1038/cdd.2012.117openalex-snapshot
Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging
inferredcites →https://doi.org/10.1038/cdd.2012.123openalex-snapshot
TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses
inferredcites →https://doi.org/10.1038/cdd.2012.13openalex-snapshot
Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice
inferredcites →https://doi.org/10.1038/cdd.2012.20openalex-snapshot
STAT3 can serve as a hit in the process of malignant transformation of primary cells
inferredcites →https://doi.org/10.1038/cdd.2012.62openalex-snapshot
SIRT3 protects from hypoxia and staurosporine-mediated cell death by maintaining mitochondrial membrane potential and intracellular pH
inferredcites →https://doi.org/10.1038/cdd.2012.81openalex-snapshot
The pathways of mitophagy for quality control and clearance of mitochondria
inferredcites →https://doi.org/10.1038/cddis.2010.67openalex-snapshot
Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells
inferredcites →https://doi.org/10.1038/cddis.2011.112openalex-snapshot
Neurodegenerative processes in Huntington's disease
inferredcites →https://doi.org/10.1038/cddis.2011.117openalex-snapshot
A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics
inferredcites →https://doi.org/10.1038/cddis.2011.12openalex-snapshot
The role of reactive oxygen species and autophagy in safingol-induced cell death
inferredcites →https://doi.org/10.1038/cddis.2011.122openalex-snapshot
Role of the promyelocytic leukaemia protein in cell death regulation
inferredcites →https://doi.org/10.1038/cddis.2011.128openalex-snapshot
Oxygen matters: tissue culture oxygen levels affect mitochondrial function and structure as well as responses to HIV viroproteins
inferredcites →https://doi.org/10.1038/cddis.2011.139openalex-snapshot
Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells
inferredcites →https://doi.org/10.1038/cddis.2011.141openalex-snapshot
Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer
inferredcites →https://doi.org/10.1038/cddis.2011.33openalex-snapshot
Disruption of the MDM2–p53 interaction strongly potentiates p53-dependent apoptosis in cisplatin-resistant human testicular carcinoma cells via the Fas/FasL pathway
inferredcites →https://doi.org/10.1038/cddis.2011.36openalex-snapshot
Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism
inferredcites →https://doi.org/10.1038/cddis.2011.39openalex-snapshot
Blockade of Hsp90 by 17AAG antagonizes MDMX and synergizes with Nutlin to induce p53-mediated apoptosis in solid tumors
inferredcites →https://doi.org/10.1038/cddis.2011.42openalex-snapshot
Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1
inferredcites →https://doi.org/10.1038/cddis.2011.45openalex-snapshot
NF-Y joins E2Fs, p53 and other stress transcription factors at the apoptosis table
inferredcites →https://doi.org/10.1038/cddis.2011.48openalex-snapshot
Reciprocal influence of the p53 and the hypoxic pathways
inferredcites →https://doi.org/10.1038/cddis.2011.56openalex-snapshot
Enhancement of autophagy is a potential modality for tumors refractory to radiotherapy
inferredcites →https://doi.org/10.1038/cddis.2011.69openalex-snapshot
Reactive oxygen species initiate luminal but not basal cell death in cultured human mammary alveolar structures: a potential regulator of involution
inferredcites →https://doi.org/10.1038/cddis.2011.70openalex-snapshot
Mechanism of cell death resulting from DNA interstrand cross-linking in mammalian cells
inferredcites →https://doi.org/10.1038/cddis.2011.76openalex-snapshot
Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32
inferredcites →https://doi.org/10.1038/cddis.2011.86openalex-snapshot
Metformin inhibits melanoma development through autophagy and apoptosis mechanisms
inferredcites →https://doi.org/10.1038/cddis.2011.96openalex-snapshot
Hydrogen peroxide: a Jekyll and Hyde signalling molecule
inferredcites →https://doi.org/10.1038/cddis.2012.10openalex-snapshot
Inhibition of Casein kinase-2 induces p53-dependent cell cycle arrest and sensitizes glioblastoma cells to tumor necrosis factor (TNFα)-induced apoptosis through SIRT1 inhibition
inferredcites →https://doi.org/10.1038/cddis.2012.111openalex-snapshot
Apoptosis and autophagy have opposite roles on imatinib-induced K562 leukemia cell senescence
inferredcites →https://doi.org/10.1038/cddis.2012.13openalex-snapshot
Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy
inferredcites →https://doi.org/10.1038/cddis.2012.139openalex-snapshot
Spermidine promotes stress resistance in Drosophila melanogaster through autophagy-dependent and -independent pathways
inferredcites →https://doi.org/10.1038/cddis.2012.140openalex-snapshot
Proliferation and tissue remodeling in cancer: the hallmarks revisited
inferredcites →https://doi.org/10.1038/cddis.2012.15openalex-snapshot
Re-oxygenation causes hypoxic tumor regression through restoration of p53 wild-type conformation and post-translational modifications
inferredcites →https://doi.org/10.1038/cddis.2012.27openalex-snapshot
Regulation of p73 activity by post-translational modifications
inferredcites →https://doi.org/10.1038/cddis.2012.35openalex-snapshot
Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents
inferredcites →https://doi.org/10.1038/nature01764openalex-snapshot
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
inferredcites →https://doi.org/10.1038/nature03354openalex-snapshot
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
inferredcites →https://doi.org/10.1038/nature05327openalex-snapshot
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
inferredcites →https://doi.org/10.1038/nature05337openalex-snapshot
p63 protects the female germ line during meiotic arrest
inferredcites →https://doi.org/10.1038/nature05529openalex-snapshot
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
inferredcites →https://doi.org/10.1038/nature05541openalex-snapshot
Restoration of p53 function leads to tumour regression in vivo
inferredcites →https://doi.org/10.1038/nature05949openalex-snapshot
Delayed ageing through damage protection by the Arf/p53 pathway
inferredcites →https://doi.org/10.1038/nature06322openalex-snapshot
mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex
inferredcites →https://doi.org/10.1038/nature06642openalex-snapshot
A skin microRNA promotes differentiation by repressing ‘stemness’
inferredcites →https://doi.org/10.1038/nature08040openalex-snapshot
Bmi1 regulates mitochondrial function and the DNA damage response pathway
inferredcites →https://doi.org/10.1038/nature08221openalex-snapshot
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
inferredcites →https://doi.org/10.1038/nature08619openalex-snapshot
Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila
inferredcites →https://doi.org/10.1038/nature09526openalex-snapshot
Selective activation of p53-mediated tumour suppression in high-grade tumours
inferredcites →https://doi.org/10.1038/nature09535openalex-snapshot
Stage-specific sensitivity to p53 restoration during lung cancer progression
inferredcites →https://doi.org/10.1038/nature09787openalex-snapshot
Telomere dysfunction induces metabolic and mitochondrial compromise
inferredcites →https://doi.org/10.1038/nature10296openalex-snapshot
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
inferredcites →https://doi.org/10.1038/nature10600openalex-snapshot
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
inferredcites →https://doi.org/10.1038/ncb1024openalex-snapshot
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts
inferredcites →https://doi.org/10.1038/ncb1634openalex-snapshot
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
inferredcites →https://doi.org/10.1038/ncb1730openalex-snapshot
Regulation of autophagy by cytoplasmic p53
inferredcites →https://doi.org/10.1038/ncb1975openalex-snapshot
Induction of autophagy by spermidine promotes longevity
inferredcites →https://doi.org/10.1038/ncb1988openalex-snapshot
TAp63 induces senescence and suppresses tumorigenesis in vivo
inferredcites →https://doi.org/10.1038/ncb2100openalex-snapshot
Puma is required for p53-induced depletion of adult stem cells
inferredcites →https://doi.org/10.1038/ncomms1001openalex-snapshot
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
inferredcites →https://doi.org/10.1038/ng0695-175openalex-snapshot
A subset of p53-deficient embryos exhibit exencephaly
inferredcites →https://doi.org/10.1038/nm.2033openalex-snapshot
Inhibition of the c-Abl–TAp63 pathway protects mouse oocytes from chemotherapy-induced death
inferredcites →https://doi.org/10.1038/nm1042openalex-snapshot
The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis
inferredcites →https://doi.org/10.1038/nrc2012openalex-snapshot
Regulating the p53 pathway: in vitro hypotheses, in vivo veritas
inferredcites →https://doi.org/10.1038/nrc2440openalex-snapshot
Living on a break: cellular senescence as a DNA-damage response
inferredcites →https://doi.org/10.1038/nrc2562openalex-snapshot
How does SIRT1 affect metabolism, senescence and cancer?
inferredcites →https://doi.org/10.1038/nrc2763openalex-snapshot
Awakening guardian angels: drugging the p53 pathway
inferredcites →https://doi.org/10.1038/nrc2772openalex-snapshot
Senescence in tumours: evidence from mice and humans
inferredcites →https://doi.org/10.1038/nrm2233openalex-snapshot
Cellular senescence: when bad things happen to good cells
inferredcites →https://doi.org/10.1038/nrm2245openalex-snapshot
Autophagy: from phenomenology to molecular understanding in less than a decade
inferredcites →https://doi.org/10.1038/nrm3025openalex-snapshot
mTOR: from growth signal integration to cancer, diabetes and ageing
inferredcites →https://doi.org/10.1038/nrm3086openalex-snapshot
The p53 family: guardians of maternal reproduction
inferredcites →https://doi.org/10.1038/nrm3293openalex-snapshot
Sirtuins as regulators of metabolism and healthspan
inferredcites →https://doi.org/10.1038/nrm3352openalex-snapshot
Axis of ageing: telomeres, p53 and mitochondria
inferredcites →https://doi.org/10.1038/onc.2010.188openalex-snapshot
Pharmacological reactivation of mutant p53: from protein structure to the cancer patient
inferredcites →https://doi.org/10.1038/onc.2010.285openalex-snapshot
The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB–P53 pathways
inferredcites →https://doi.org/10.1038/onc.2010.419openalex-snapshot
The p16INK4A tumor suppressor regulates cellular oxidative stress
inferredcites →https://doi.org/10.1038/onc.2010.457openalex-snapshot
Negative regulation of the tumor suppressor p53 gene by microRNAs
inferredcites →https://doi.org/10.1038/onc.2010.492openalex-snapshot
NRF2, cancer and calorie restriction
inferredcites →https://doi.org/10.1038/onc.2010.520openalex-snapshot
Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence
inferredcites →https://doi.org/10.1038/onc.2010.539openalex-snapshot
Genome-wide shRNA screen reveals increased mitochondrial dependence upon mTORC2 addiction
inferredcites →https://doi.org/10.1038/onc.2010.603openalex-snapshot
Targeting the Akt/mTOR pathway in Brca1-deficient cancers
inferredcites →https://doi.org/10.1038/onc.2010.614openalex-snapshot
p16Ink4a overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors
inferredcites →https://doi.org/10.1038/onc.2010.630openalex-snapshot
The long and winding road to rational treatment of cancer associated with LKB1/AMPK/TSC/mTORC1 signaling
inferredcites →https://doi.org/10.1038/onc.2011.135openalex-snapshot
Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional
inferredcites →https://doi.org/10.1038/onc.2011.220openalex-snapshot
The autophagy conundrum in cancer: influence of tumorigenic metabolic reprogramming
inferredcites →https://doi.org/10.1038/onc.2011.270openalex-snapshot
MYCN sensitizes neuroblastoma to the MDM2-p53 antagonists Nutlin-3 and MI-63
inferredcites →https://doi.org/10.1038/onc.2011.277openalex-snapshot
E2F1-dependent oncogenic addiction of melanoma cells to MDM2
inferredcites →https://doi.org/10.1038/onc.2011.295openalex-snapshot
The autophagic paradox in cancer therapy
inferredcites →https://doi.org/10.1038/onc.2011.309openalex-snapshot
Synergistic growth inhibition based on small-molecule p53 activation as treatment for intraocular melanoma
inferredcites →https://doi.org/10.1038/onc.2011.327openalex-snapshot
ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence
inferredcites →https://doi.org/10.1038/onc.2011.34openalex-snapshot
Transcriptional regulation of cellular senescence
inferredcites →https://doi.org/10.1038/onc.2011.350openalex-snapshot
Cellular features of senescence during the evolution of human and murine ductal pancreatic cancer
inferredcites →https://doi.org/10.1038/onc.2011.394openalex-snapshot
AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy
inferredcites →https://doi.org/10.1038/onc.2011.45openalex-snapshot
Epigenetic regulation of aging stem cells
inferredcites →https://doi.org/10.1038/onc.2011.74openalex-snapshot
Blockade of the NFκB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo
inferredcites →https://doi.org/10.1038/onc.2012.111openalex-snapshot
The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells
inferredcites →https://doi.org/10.1038/onc.2012.252openalex-snapshot
Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells
inferredcites →https://doi.org/10.1038/onc.2012.312openalex-snapshot
RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth
inferredcites →https://doi.org/10.1038/onc.2012.338openalex-snapshot
The mTOR inhibitor rapamycin opposes carcinogenic changes to epidermal Akt1/PKBα isoform signaling
inferredcites →https://doi.org/10.1038/onc.2012.45openalex-snapshot
Carcinogen-specific mutational and epigenetic alterations in INK4A, INK4B and p53 tumour-suppressor genes drive induced senescence bypass in normal diploid mammalian cells
inferredcites →https://doi.org/10.1038/onc.2012.47openalex-snapshot
Critical role of arachidonic acid-activated mTOR signaling in breast carcinogenesis and angiogenesis
inferredcites →https://doi.org/10.1038/sj.cdd.4401921openalex-snapshot
Strategies for therapeutic targeting of the p53 pathway in cancer
inferredcites →https://doi.org/10.1038/sj.cdd.4401926openalex-snapshot
Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice
showing the first 200 of 287 · page through all 287
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4630998openalex-extracted
Mesoporous Bioactive Glass Scaffolds Delivering BMSCs Osteoinductive EVs lncRNA Promote Senescent Bone Defect Repair by Targeting the miR-1843a-5p/mob3a/YAP Axis
inferred← citeshttps://doi.org/10.1002/9780470015902.a0025372openalex-snapshot
Cancer and the Ageing Process
inferred← citeshttps://doi.org/10.1002/adfm.202107990openalex-snapshot
Targeted Therapeutics Delivery by Exploiting Biophysical Properties of Senescent Cells
inferred← citeshttps://doi.org/10.1002/adfm.202514253openalex-snapshot
Neodymium‐Modified Molybdenum Blue Nanoclusters Alleviate Polycystic Ovary Syndrome via Radical Scavenging
inferred← citeshttps://doi.org/10.1002/advs.202307319openalex-snapshot
Morusin Alleviates Aortic Valve Calcification by Inhibiting Valve Interstitial Cell Senescence Through Ccnd1/Trim25/Nrf2 Axis
inferred← citeshttps://doi.org/10.1002/advs.202414682openalex-snapshot
Nuclear Translocation of S100A9 Triggers Senescence of Human Amnion Fibroblasts by De‐Repressing LINE1 Via Heterochromatin Erosion at Parturition
inferred← citeshttps://doi.org/10.1002/advs.76740openalex-snapshot
Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation
inferred← citeshttps://doi.org/10.1002/ame2.70165openalex-snapshot
Gorab deficiency in skin dermis accelerates aging and is associated with dysregulation of RCHY1 ‐mediated P53 ubiquitination
inferred← citeshttps://doi.org/10.1002/art.41213openalex-snapshot
Role of Low‐Density Lipoprotein in Early Vascular Aging Associated With Systemic Lupus Erythematosus
inferred← citeshttps://doi.org/10.1002/biof.1624openalex-snapshot
6‐Phosphogluconate dehydrogenase fuels multiple aspects of cancer cells: From cancer initiation to metastasis and chemoresistance
inferred← citeshttps://doi.org/10.1002/cph4.70041openalex-snapshot
The Role of p53‐Mediated Cellular Senescence in Idiopathic Pulmonary Fibrosis
inferred← citeshttps://doi.org/10.1002/cphy.c190017openalex-snapshot
Oxidative Stress in Pulmonary Fibrosis
inferred← citeshttps://doi.org/10.1002/dvdy.672openalex-snapshot
wnt10a is required for zebrafish median fin fold maintenance and adult unpaired fin metamorphosis
inferred← citeshttps://doi.org/10.1002/fsn3.72241openalex-snapshot
Phillyrin Alleviates Memory Impairment in D‐Galactose‐Induced Aged Mice by Suppressing Hippocampal Neuroinflammation via the TLR4 / NF ‐ κB Signaling Pathway
inferred← citeshttps://doi.org/10.1002/hed.24129openalex-snapshot
Down‐regulation of malic enzyme 1 and 2: Sensitizing head and neck squamous cell carcinoma cells to therapy‐induced senescence
inferred← citeshttps://doi.org/10.1002/ijc.30070openalex-snapshot
Hyperthermia adds to trabectedin effectiveness and thermal enhancement is associated with BRCA2 degradation and impairment of DNA homologous recombination repair
inferred← citeshttps://doi.org/10.1002/ijc.32709openalex-snapshot
Effects of the antifungal agent ciclopirox in HPV‐positive cancer cells: Repression of viral E6/E7 oncogene expression and induction of senescence and apoptosis
inferred← citeshttps://doi.org/10.1002/iub.1335openalex-snapshot
Tumour suppressors and cellular senescence
inferred← citeshttps://doi.org/10.1002/iub.1930openalex-snapshot
Malic enzyme 2 as a potential therapeutic drug target for cancer
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2020.tb00120.xopenalex-snapshot
Oxidative Stress in Pulmonary Fibrosis
inferred← citeshttps://doi.org/10.1002/jbt.70065openalex-snapshot
Autophagy in the Cellular Consequences of Tobacco Smoking: Insights into Senescence
inferred← citeshttps://doi.org/10.1002/jcb.26763openalex-snapshot
Retracted : MicroRNA‐183 induces epithelial‐mesenchymal transition and promotes endometrial cancer cell migration and invasion in by targeting CPEB1
inferred← citeshttps://doi.org/10.1002/jcp.24574openalex-snapshot
Non‐Cell Autonomous or Secretory Tumor Suppression
inferred← citeshttps://doi.org/10.1002/jcp.25807openalex-snapshot
Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha‐galactosidase A (GLA) enzymes
inferred← citeshttps://doi.org/10.1002/jcp.26601openalex-snapshot
Thiostrepton degrades mutant p53 by eliciting an autophagic response in SW480 cells
inferred← citeshttps://doi.org/10.1002/jemt.24147openalex-snapshot
Emerging roles of circRNAs in mice kidney with aging
inferred← citeshttps://doi.org/10.1002/mc.22627openalex-snapshot
p16INK4A enhances the transcriptional and the apoptotic functions of p53 through DNA‐dependent interaction
inferred← citeshttps://doi.org/10.1002/mc.70022openalex-snapshot
Inhibition of Growth and Survival of Head and Neck Cancer Cells by Silibinin Involves the Down‐Regulation of Erk1/2, AKT and STAT3 Signaling
inferred← citeshttps://doi.org/10.1002/mco2.29openalex-snapshot
Transgenic zebrafish for modeling hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1002/mco2.475openalex-snapshot
AMPK‐upregulated microRNA‐708 plays as a suppressor of cellular senescence and aging via downregulating disabled‐2 and mTORC1 activation
inferred← citeshttps://doi.org/10.1002/mco2.70261openalex-snapshot
Tet Methylcytosine Dioxygenase 3 Promotes Cardiovascular Senescence by DNA 5‐Hydroxymethylcytosine‐Mediated Sp1 Transcription Factor Expression
inferred← citeshttps://doi.org/10.1002/path.4478openalex-snapshot
UBTD1 induces cellular senescence through an UBTD1 –Mdm2/p53 positive feedback loop
inferred← citeshttps://doi.org/10.1002/ptr.7142openalex-snapshot
The p53/p21/p16 and PI3K /Akt signaling pathways are involved in the ameliorative effects of maltol on D‐galactose‐induced liver and kidney aging and injury
inferred← citeshttps://doi.org/10.1002/ptr.7290openalex-snapshot
A mechanistic insight into the biological activities of urolithins as gut microbial metabolites of ellagitannins
inferred← citeshttps://doi.org/10.1002/rmv.1823openalex-snapshot
Signaling pathways in HPV‐associated cancers and therapeutic implications
inferred← citeshttps://doi.org/10.1002/rmv.70195openalex-snapshot
Oncoviruses at the Crossroads of Ageing and Cancer: Molecular Mechanisms and Key Signalling Pathways
inferred← citeshttps://doi.org/10.1002/tox.22847openalex-snapshot
Protective effects of galangin against H2O2‐induced aging via the IGF‐1 signaling pathway in human dermal fibroblasts
inferred← citeshttps://doi.org/10.1002/tox.23155openalex-snapshot
p16 loss facilitate hydroquinone‐induced malignant transformation of TK6 cells through promoting cell proliferation and accelerating the cell cycle progression
inferred← citeshttps://doi.org/10.1002/wrna.1297openalex-snapshot
Noncoding RNA control of cellular senescence
inferred← citeshttps://doi.org/10.1007/978-3-030-44903-2_6openalex-snapshot
Targeted Senolytic Strategies Based on the Senescent Surfaceome
inferred← citeshttps://doi.org/10.1007/978-3-030-55035-6_16openalex-snapshot
Is Adipose Tissue the Fountain of Youth? The Impact of Adipose Stem Cell Aging on Metabolic Homeostasis, Longevity, and Cell-Based Therapies
inferred← citeshttps://doi.org/10.1007/978-3-030-58532-7_16openalex-snapshot
Cell Proliferation, Survival, Necrosis and Apoptosis
inferred← citeshttps://doi.org/10.1007/978-3-319-16015-3_9openalex-snapshot
The Biology of Immortality
inferred← citeshttps://doi.org/10.1007/978-3-319-23246-1_3openalex-snapshot
The Impact of Aging on Cancer Progression and Treatment
inferred← citeshttps://doi.org/10.1007/978-4-431-55873-6_18openalex-snapshot
Molecular Insights into the Regulation of Apoptosis and Cellular Senescence and Their Implications for Cancer
inferred← citeshttps://doi.org/10.1007/978-94-017-9211-0_2openalex-snapshot
Alterations of p63 and p73 in Human Cancers
inferred← citeshttps://doi.org/10.1007/978-981-32-9005-1_21openalex-snapshot
The Biology of Aging and Cancer: A Complex Association
inferred← citeshttps://doi.org/10.1007/978-981-96-1041-9_6openalex-snapshot
Cellular Senescence and Stem Cell Exhaustion: Implications for Aging and Regeneration
inferred← citeshttps://doi.org/10.1007/s00011-026-02378-4openalex-snapshot
PP4 deficiency drives airway epithelial senescence via the PERK-eIF2α-ATF4-p21 axis in severe asthma
inferred← citeshttps://doi.org/10.1007/s00018-021-04025-zopenalex-snapshot
Microgravity and space radiation inhibit autophagy in human capillary endothelial cells, through either opposite or synergistic effects on specific molecular pathways
inferred← citeshttps://doi.org/10.1007/s00018-023-04950-1openalex-snapshot
Loss of fragile WWOX gene leads to senescence escape and genome instability
inferred← citeshttps://doi.org/10.1007/s00018-023-04964-9openalex-snapshot
Intracellular FGF1 protects cells from apoptosis through direct interaction with p53
inferred← citeshttps://doi.org/10.1007/s00109-014-1182-xopenalex-snapshot
Histone demethylase Jumonji D3 (JMJD3/KDM6B) at the nexus of epigenetic regulation of inflammation and the aging process
inferred← citeshttps://doi.org/10.1007/s00109-022-02187-2openalex-snapshot
Deciphering therapeutic options for neurodegenerative diseases: insights from SIRT1
inferred← citeshttps://doi.org/10.1007/s00393-022-01260-yopenalex-snapshot
Der Rolle der DNA-Schadensantwort bei granulomatösen Erkrankungen
inferred← citeshttps://doi.org/10.1007/s00395-019-0760-zopenalex-snapshot
Molecular pathways involved in the cardioprotective effects of intravenous statin administration during ischemia
inferred← citeshttps://doi.org/10.1007/s00411-019-00825-xopenalex-snapshot
DNA damage response in peripheral mouse blood leukocytes in vivo after variable, low-dose rate exposure
inferred← citeshttps://doi.org/10.1007/s00417-023-06160-8openalex-snapshot
TRIM25 inhibition attenuates inflammation, senescence, and oxidative stress in microvascular endothelial cells induced by hyperglycemia
inferred← citeshttps://doi.org/10.1007/s00520-016-3254-7openalex-snapshot
Mechanisms of skin aging induced by EGFR inhibitors
inferred← citeshttps://doi.org/10.1007/s10266-021-00630-3openalex-snapshot
An in vitro senescence model of gingival epithelial cell induced by hydrogen peroxide treatment
inferred← citeshttps://doi.org/10.1007/s10522-017-9698-4openalex-snapshot
Molecular connections of obesity and aging: a focus on adipose protein 53 and retinoblastoma protein
inferred← citeshttps://doi.org/10.1007/s10522-019-09841-2openalex-snapshot
IL-6 deficiency attenuates p53 protein accumulation in aged male mouse hippocampus
inferred← citeshttps://doi.org/10.1007/s10522-022-09997-4openalex-snapshot
An evaluation of aging measures: from biomarkers to clocks
inferred← citeshttps://doi.org/10.1007/s10522-024-10162-2openalex-snapshot
Nicotinamide mononucleotide suppresses cellular senescence and increases aquaporin 5 expression in the submandibular gland of aged male mice to ameliorate aging-related dry mouth
inferred← citeshttps://doi.org/10.1007/s10522-024-10164-0openalex-snapshot
GDF15/MIC-1: a stress-induced immunosuppressive factor which promotes the aging process
inferred← citeshttps://doi.org/10.1007/s10534-020-00269-7openalex-snapshot
Antiproliferative activity exerted by tricyclohexylphosphanegold(I) n-mercaptobenzoate against MCF-7 and A2780 cell lines: the role of p53 signaling pathways
inferred← citeshttps://doi.org/10.1007/s10876-021-02152-yopenalex-snapshot
Senolytic Effect of Cerium Oxide Nanoparticles (CeO2 NPs) by Attenuating p38/NF-кB, and p53/p21 Signaling Pathways
inferred← citeshttps://doi.org/10.1007/s11010-025-05355-3openalex-snapshot
Balancing senescence and apoptosis: therapeutic insights into aging and cancer
inferred← citeshttps://doi.org/10.1007/s11010-026-05593-zopenalex-snapshot
P2Y12-AMPKα2 signaling contributes to cardiomyocyte senescence in doxorubicin-induced heart failure
inferred← citeshttps://doi.org/10.1007/s11011-022-00937-2openalex-snapshot
Paeoniflorin ameliorates cognitive impairment in Parkinson’s disease via JNK/p53 signaling
inferred← citeshttps://doi.org/10.1007/s11033-021-06898-6openalex-snapshot
Hormetic effect of low doses of rapamycin triggers anti-aging cascades in WRL-68 cells by modulating an mTOR-mitochondria cross-talk
inferred← citeshttps://doi.org/10.1007/s11357-021-00344-yopenalex-snapshot
Deletion of Nrip1 delays skin aging by reducing adipose-derived mesenchymal stem cells (ADMSCs) senescence, and maintaining ADMSCs quiescence
inferred← citeshttps://doi.org/10.1007/s11357-021-00460-9openalex-snapshot
Divergent regulation of lncRNA expression by ischemia in adult and aging mice
inferred← citeshttps://doi.org/10.1007/s11357-024-01089-0openalex-snapshot
Senolytic treatment fails to improve ovarian reserve or fertility in female mice
inferred← citeshttps://doi.org/10.1007/s11897-021-00519-wopenalex-snapshot
The Interplay Between Autophagy and Senescence in Anthracycline Cardiotoxicity
inferred← citeshttps://doi.org/10.1007/s12011-023-04021-3openalex-snapshot
Ginkgo Biloba Extract Can Antagonize Subchronic Arsenite Exposure-Induced Hepatocyte Senescence by Inhibiting Oxidative Damage and Inflammation in Rats
inferred← citeshttps://doi.org/10.1007/s12012-021-09704-8openalex-snapshot
Metoprolol Protects Against Arginine Vasopressin-Induced Cellular Senescence in H9C2 Cardiomyocytes by Regulating the Sirt1/p53/p21 Axis
inferred← citeshttps://doi.org/10.1007/s12015-020-10095-6openalex-snapshot
MicroRNA Profiling in Mesenchymal Stromal Cells: the Tissue Source as the Missing Piece in the Puzzle of Ageing
inferred← citeshttps://doi.org/10.1007/s12015-024-10790-8openalex-snapshot
Effects of Replicative Senescence of Human Chorionic MSCs on their EV-miRNA Profile
inferred← citeshttps://doi.org/10.1007/s12035-019-01800-9openalex-snapshot
Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis
inferred← citeshttps://doi.org/10.1007/s12035-019-1500-yopenalex-snapshot
Systematic Review of miRNA as Biomarkers in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1007/s12094-019-02236-2openalex-snapshot
Li–Fraumeni syndrome heterogeneity
inferred← citeshttps://doi.org/10.1007/s12672-025-03893-2openalex-snapshot
Unveiling oncogene-induced senescence: a new frontier in prostate cancer prognosis and therapy
inferred← citeshttps://doi.org/10.1007/s13238-019-0653-9openalex-snapshot
JMJD3 in the regulation of human diseases
inferred← citeshttps://doi.org/10.1007/s13402-016-0311-7openalex-snapshot
CDKN2A-p53 mediated antitumor effect of Lupeol in head and neck cancer
inferred← citeshttps://doi.org/10.1007/s13402-019-00452-0openalex-snapshot
Interplay between HSF1 and p53 signaling pathways in cancer initiation and progression: non-oncogene and oncogene addiction
inferred← citeshttps://doi.org/10.1007/s40618-020-01255-zopenalex-snapshot
Molecular basis of ageing in chronic metabolic diseases
inferred← citeshttps://doi.org/10.1007/s40778-018-0128-6openalex-snapshot
Signaling Pathways Regulating Hematopoietic Stem Cell and Progenitor Aging
inferred← citeshttps://doi.org/10.1007/s44337-025-00502-7openalex-snapshot
The dual role of cellular senescence in tumor occurrence and development
inferred← citeshttps://doi.org/10.1016/b978-0-12-396971-2.00009-9openalex-snapshot
The Circadian Clock in Cancer Development and Therapy
inferred← citeshttps://doi.org/10.1016/b978-0-12-800957-4.00018-7openalex-snapshot
Epigenetics and Aging
inferred← citeshttps://doi.org/10.1016/b978-0-12-803239-8.00016-8openalex-snapshot
Epigenetics of Skin Disorders
inferred← citeshttps://doi.org/10.1016/b978-0-12-813087-2.00011-7openalex-snapshot
Machine-Learning Approach for Ribonucleic Acid Primary and Secondary Structure Prediction from Images
inferred← citeshttps://doi.org/10.1016/b978-0-12-823928-5.00011-6openalex-snapshot
Epigenetics of skin disorders
inferred← citeshttps://doi.org/10.1016/b978-0-323-90965-5.00010-6openalex-snapshot
Structure and function of the cell
inferred← citeshttps://doi.org/10.1016/b978-0-323-91617-2.00010-9openalex-snapshot
Senescence in aging
inferred← citeshttps://doi.org/10.1016/b978-0-443-15500-0.00016-5openalex-snapshot
Age-related disease: Cancer, telomerase, and cell aging
inferred← citeshttps://doi.org/10.1016/b978-0-443-33978-3.00003-4openalex-snapshot
Multifaceted role of selenium in mitigating ageing via epigenetic and antioxidative regulations
inferred← citeshttps://doi.org/10.1016/bs.apcsb.2018.09.004openalex-snapshot
Inflammatory response and its relation to sphingolipid metabolism proteins: Chaperones as potential indirect anti-inflammatory agents
inferred← citeshttps://doi.org/10.1016/bs.apha.2025.01.019openalex-snapshot
Cellular senescence and senotherapeutics in cardiovascular diseases
inferred← citeshttps://doi.org/10.1016/j.abb.2014.02.008openalex-snapshot
Methionine sulfoxide reductase B3 deficiency inhibits cell growth through the activation of p53–p21 and p27 pathways
inferred← citeshttps://doi.org/10.1016/j.abb.2014.08.017openalex-snapshot
Nicotinamide N-methyltransferase enhances the capacity of tumorigenesis associated with the promotion of cell cycle progression in human colorectal cancer cells
inferred← citeshttps://doi.org/10.1016/j.actbio.2024.01.044openalex-snapshot
Mesoporous bioactive glass scaffolds for the delivery of bone marrow stem cell-derived osteoinductive extracellular vesicles lncRNA promote senescent bone defect repair by targeting the miR-1843a-5p/Mob3a/YAP axis
inferred← citeshttps://doi.org/10.1016/j.ajpath.2016.08.004openalex-snapshot
Choroidal Involution Is Associated with a Progressive Degeneration of the Outer Retinal Function in a Model of Retinopathy of Prematurity
inferred← citeshttps://doi.org/10.1016/j.archger.2021.104461openalex-snapshot
Global Single Clustering of Phenotype-Associated Human Aging Genes in the Co-Expression and Physical Interaction Networks: An OMIM-Based Investigative Review.
inferred← citeshttps://doi.org/10.1016/j.arr.2018.06.003openalex-snapshot
Nrf2: Molecular and epigenetic regulation during aging
inferred← citeshttps://doi.org/10.1016/j.arr.2020.101036openalex-snapshot
Biomarkers, oxidative stress and autophagy in skin aging
inferred← citeshttps://doi.org/10.1016/j.arr.2024.102502openalex-snapshot
Targeting senescent cells in atherosclerosis: Pathways to novel therapies
inferred← citeshttps://doi.org/10.1016/j.arr.2024.102503openalex-snapshot
Senoinflammation as the underlying mechanism of aging and its modulation by calorie restriction
inferred← citeshttps://doi.org/10.1016/j.bbabio.2022.148949openalex-snapshot
Inner mitochondrial membrane structure and fusion dynamics are altered in senescent human iPSC-derived and primary rat cardiomyocytes
inferred← citeshttps://doi.org/10.1016/j.bbadis.2013.12.015openalex-snapshot
p53 and mitochondrial function in neurons
inferred← citeshttps://doi.org/10.1016/j.bbadis.2016.07.005openalex-snapshot
Aberrant protein phosphorylation in Alzheimer disease brain disturbs pro-survival and cell death pathways
inferred← citeshttps://doi.org/10.1016/j.bbadis.2018.01.018openalex-snapshot
Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2014.10.003openalex-snapshot
Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2014.12.006openalex-snapshot
The type 2 inositol 1,4,5-trisphosphate receptor, emerging functions for an intriguing Ca2+-release channel
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2016.06.008openalex-snapshot
Prostaglandin EP2 receptor signaling protects human trabecular meshwork cells from apoptosis induced by ER stress through down-regulation of p53
inferred← citeshttps://doi.org/10.1016/j.bbamem.2019.183061openalex-snapshot
Nanomechanical insights: Amyloid beta oligomer-induced senescent brain endothelial cells
inferred← citeshttps://doi.org/10.1016/j.bbcan.2017.08.001openalex-snapshot
p53 stability is regulated by diverse deubiquitinating enzymes
inferred← citeshttps://doi.org/10.1016/j.bbcan.2018.06.001openalex-snapshot
Control of metabolism by p53 – Cancer and beyond
inferred← citeshttps://doi.org/10.1016/j.bbcan.2021.188662openalex-snapshot
The potential roles of p53 signaling reactivation in pancreatic cancer therapy
inferred← citeshttps://doi.org/10.1016/j.bbi.2023.12.030openalex-snapshot
Role of astrocyte senescence regulated by the non– canonical autophagy in the neuroinflammation associated to cerebral malaria
inferred← citeshttps://doi.org/10.1016/j.bbrc.2020.05.083openalex-snapshot
Atg5-mediated autophagy controls apoptosis/anoikis via p53/Rb pathway in naked mole-rat fibroblasts
inferred← citeshttps://doi.org/10.1016/j.bbrc.2020.09.096openalex-snapshot
Isoparvifuran isolated from Dalbergia odorifera attenuates H2O2-induced senescence of BJ cells through SIRT1 activation and AKT/mTOR pathway inhibition
inferred← citeshttps://doi.org/10.1016/j.bbrc.2021.09.020openalex-snapshot
Insights on the disruption of the complex between human positive coactivator 4 and p53 by small molecules
inferred← citeshttps://doi.org/10.1016/j.bbrc.2023.05.098openalex-snapshot
BTG2 acts as an inducer of muscle stem cell senescence
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.151506openalex-snapshot
Comparative analysis of transcriptomic profiles of mesenchymal stem cells at the onset of senescence and after exposure to acute exogenous oxidative stress
inferred← citeshttps://doi.org/10.1016/j.bcp.2021.114651openalex-snapshot
p53 regulated senescence mechanism and role of its modulators in age-related disorders
inferred← citeshttps://doi.org/10.1016/j.bcp.2022.115159openalex-snapshot
Trabectedin suppresses escape from therapy-induced senescence in tumor cells by interfering with glutamine metabolism
inferred← citeshttps://doi.org/10.1016/j.biocel.2015.12.010openalex-snapshot
Absence of AMPKα2 accelerates cellular senescence via p16 induction in mouse embryonic fibroblasts
inferred← citeshttps://doi.org/10.1016/j.biocel.2016.03.018openalex-snapshot
Loss of interactions between p53 and survivin gene in mesenchymal stem cells after spontaneous transformation in vitro
inferred← citeshttps://doi.org/10.1016/j.biocel.2017.09.005openalex-snapshot
A progressive reduction in autophagic capacity contributes to induction of replicative senescence in Hs68 cells
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2014.08.034openalex-snapshot
Delayed animal aging through the recovery of stem cell senescence by platelet rich plasma
inferred← citeshttps://doi.org/10.1016/j.biopha.2019.108669openalex-snapshot
Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2019.04.007openalex-snapshot
Anti-cancer effects of polyphenols via targeting p53 signaling pathway: updates and future directions
inferred← citeshttps://doi.org/10.1016/j.bmc.2024.118053openalex-snapshot
Exploring the antiproliferative and proapoptotic activities of new pyridopyrimidine derivatives and their analogs
inferred← citeshttps://doi.org/10.1016/j.canlet.2018.04.009openalex-snapshot
Par-4-dependent p53 up-regulation plays a critical role in thymoquinone-induced cellular senescence in human malignant glioma cells
inferred← citeshttps://doi.org/10.1016/j.canlet.2021.11.025openalex-snapshot
Identification of a novel catalytic inhibitor of topoisomerase II alpha that engages distinct mechanisms in p53wt or p53−/− cells to trigger G2/M arrest and senescence
inferred← citeshttps://doi.org/10.1016/j.canlet.2023.216075openalex-snapshot
IGF2BP1-mediated N6-methyladenosine modification promotes intrahepatic cholangiocarcinoma progression
inferred← citeshttps://doi.org/10.1016/j.cellsig.2017.02.011openalex-snapshot
Ovarian tumor domain-containing protein 1 deubiquitinates and stabilizes p53
inferred← citeshttps://doi.org/10.1016/j.cellsig.2020.109850openalex-snapshot
Dysregulation of lysophospholipid signaling by p53 in malignant cells and the tumor microenvironment
inferred← citeshttps://doi.org/10.1016/j.coisb.2024.100533openalex-snapshot
From regulation of cell fate decisions towards patient-specific treatments, insights from mechanistic models of signalling pathways
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2020.111004openalex-snapshot
A Novel Biochemical Study of Anti-Ageing Potential of Eucalyptus Camaldulensis Bark Waste Standardized Extract and Silver Nanoparticles
inferred← citeshttps://doi.org/10.1016/j.csbj.2021.07.002openalex-snapshot
Exploiting the molecular basis of age and gender differences in outcomes of SARS-CoV-2 infections
inferred← citeshttps://doi.org/10.1016/j.ctarc.2021.100399openalex-snapshot
The emerging role of cellular senescence in complications of COVID-19
inferred← citeshttps://doi.org/10.1016/j.ctro.2017.10.004openalex-snapshot
Increasing genomic instability during cancer therapy in a patient with Li-Fraumeni syndrome
inferred← citeshttps://doi.org/10.1016/j.ctrv.2018.09.004openalex-snapshot
Restoring guardianship of the genome: Anticancer drug strategies to reverse oncogenic mutant p53 misfolding
inferred← citeshttps://doi.org/10.1016/j.devcel.2017.01.012openalex-snapshot
Large-Scale Analysis of CRISPR/Cas9 Cell-Cycle Knockouts Reveals the Diversity of p53-Dependent Responses to Cell-Cycle Defects
inferred← citeshttps://doi.org/10.1016/j.dnarep.2019.05.004openalex-snapshot
Crosstalk between P53 and DNA damage response in ageing
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2022.114098openalex-snapshot
Sirtuin-1 attenuates cadmium-induced renal cell senescence through p53 deacetylation
inferred← citeshttps://doi.org/10.1016/j.ejphar.2022.174977openalex-snapshot
Sirtuin 7 serves as a promising therapeutic target for cardiorenal diseases
inferred← citeshttps://doi.org/10.1016/j.ejphar.2024.176959openalex-snapshot
β-Hydroxybutyrate alleviates brain aging through the MTA1 pathway in D-galactose injured mice
inferred← citeshttps://doi.org/10.1016/j.ejphar.2024.176961openalex-snapshot
The role of cardiomyocyte senescence in cardiovascular diseases: A molecular biology update
inferred← citeshttps://doi.org/10.1016/j.envpol.2025.126972openalex-snapshot
Nanoplastics: An emerging environmental concern in age-related diseases
inferred← citeshttps://doi.org/10.1016/j.etap.2018.03.014openalex-snapshot
IGFBP-3 plays an important role in senescence as an aging marker
inferred← citeshttps://doi.org/10.1016/j.exer.2019.05.016openalex-snapshot
Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula
inferred← citeshttps://doi.org/10.1016/j.exger.2017.08.001openalex-snapshot
Interaction between mTOR pathway inhibition and autophagy induction attenuates adriamycin-induced vascular smooth muscle cell senescence through decreased expressions of p53/p21/p16
inferred← citeshttps://doi.org/10.1016/j.exger.2018.05.018openalex-snapshot
Influence of aging in the modulation of epigenetic biomarkers of carcinogenesis after exposure to air pollution
inferred← citeshttps://doi.org/10.1016/j.exger.2019.110741openalex-snapshot
Biomarkers for vascular ageing in aorta tissues and blood samples
inferred← citeshttps://doi.org/10.1016/j.exger.2021.111406openalex-snapshot
Sargahydroquinoic acid (SHQA) suppresses cellular senescence through Akt/mTOR signaling pathway
inferred← citeshttps://doi.org/10.1016/j.exger.2024.112391openalex-snapshot
p53 accelerates endothelial cell senescence in diabetic retinopathy by enhancing FoxO3a ubiquitylation and degradation via UBE2L6
inferred← citeshttps://doi.org/10.1016/j.explore.2021.11.007openalex-snapshot
Effects of intentionally treated water on the growth of mesenchymal stem cells: An exploratory study
inferred← citeshttps://doi.org/10.1016/j.fbio.2022.102164openalex-snapshot
Bioactive coumarin-derivative esculetin decreases hepatic stellate cell activation via induction of cellular senescence via the PI3K-Akt-GSK3β pathway
inferred← citeshttps://doi.org/10.1016/j.fbio.2025.108062openalex-snapshot
A novel polysaccharide with a triple-helical structure from Lonicera japonica Thunb.: Characterization and anti-aging effects
inferred← citeshttps://doi.org/10.1016/j.fct.2023.113981openalex-snapshot
γ-Oryzanol ameliorates fine dust-induced premature endothelial senescence and dysfunction via attenuating oxidative stress
inferred← citeshttps://doi.org/10.1016/j.fct.2023.114030openalex-snapshot
Oxidative stress-affected ACSL1 hydroxymethylation triggered benzene hematopoietic toxicity by inflammation and senescence
inferred← citeshttps://doi.org/10.1016/j.febslet.2014.09.043openalex-snapshot
A switch‐like dynamic mechanism for the initiation of replicative senescence
inferred← citeshttps://doi.org/10.1016/j.foodchem.2026.151390openalex-snapshot
Molecular mechanism of SIRT1 activation by polymethoxyflavonoids derived from citrus peels
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2017.04.019openalex-snapshot
Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.11.006openalex-snapshot
N-acetylcysteine ameliorates cisplatin-induced renal senescence and renal interstitial fibrosis through sirtuin1 activation and p53 deacetylation
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2020.02.017openalex-snapshot
CR6 interacting factor 1 deficiency induces premature senescence via SIRT3 inhibition in endothelial cells
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2021.07.025openalex-snapshot
Iron deficiency exacerbates cisplatin- or rhabdomyolysis-induced acute kidney injury through promoting iron-catalyzed oxidative damage
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2024.01.044openalex-snapshot
Targeting ERS-mitophagy in hippocampal neurons to explore the improvement of memory by tea polyphenols in aged type 2 diabetic rats
inferred← citeshttps://doi.org/10.1016/j.gene.2023.147675openalex-snapshot
P53 regulates CCAAT/Enhancer binding protein β gene expression
inferred← citeshttps://doi.org/10.1016/j.gpb.2022.06.001openalex-snapshot
Identification of Age-Associated Proteins and Functional Alterations in Human Retinal Pigment Epithelium
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e27478openalex-snapshot
Metformin alleviates junctional epithelium senescence via the AMPK/SIRT1/autophagy pathway in periodontitis induced by hyperglycemia
inferred← citeshttps://doi.org/10.1016/j.heliyon.2025.e42113openalex-snapshot
Molecular evidence of the inhibitory potential of melatonin against sodium arsenite toxicity
inferred← citeshttps://doi.org/10.1016/j.heliyon.2026.e44567openalex-snapshot
Cytotoxic activity of pyrimethanil on human testicular teratocarcinoma NT2/D1 cells
inferred← citeshttps://doi.org/10.1016/j.humgen.2026.201544openalex-snapshot
Cross-disease systems biology reveals shared gene regulatory networks and biomarker candidates in prostate cancer, Alzheimer's, and Parkinson's disease
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2022.09.209openalex-snapshot
Interactome battling of lncRNA CCDC144NL-AS1: Its role in the emergence and ferocity of cancer and beyond
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.139216openalex-snapshot
Structural characterization and anti-aging activity investigation of a polysaccharide from Anemarrhena asphodeloides Bge
inferred← citeshttps://doi.org/10.1016/j.jbiomech.2015.10.030openalex-snapshot
Mechanical cytoprotection: A review of cytoskeleton-protection approaches for cells
inferred← citeshttps://doi.org/10.1016/j.jchromb.2018.12.002openalex-snapshot
DoE to improve supercoiled p53-pDNA purification by O-phospho-l-tyrosine chromatography
inferred← citeshttps://doi.org/10.1016/j.jcis.2017.01.115openalex-snapshot
Curcumin-functionalized silk biomaterials for anti-aging utility
inferred← citeshttps://doi.org/10.1016/j.jconrel.2024.02.047openalex-snapshot
Fibroblast function recovery through rejuvenation effect of nanovesicles extracted from human adipose-derived stem cells irradiated with red light
inferred← citeshttps://doi.org/10.1016/j.jcyt.2014.08.005openalex-snapshot
X-ray and ultraviolet C irradiation–induced γ-H2AX and p53 formation in normal human periosteal cells in vitro: markers for quality control in cell therapy
inferred← citeshttps://doi.org/10.1016/j.jddst.2025.107400openalex-snapshot
Chrysin matodextrin cationized guar complex nanoparticles modulates lung aging induced by D-galactose in mice: Forkhead box proteins impact in cell longevity and apoptosis
inferred← citeshttps://doi.org/10.1016/j.jep.2025.120604openalex-snapshot
Typhae pollen attenuates atherosclerosis by enhancing vascular endothelium function and lipid metabolism
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2022.128366openalex-snapshot
Metabolic and DNA checkpoints for the enhancement of Al tolerance
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.135583openalex-snapshot
Identification of sanguinarine as a novel antagonist for perfluorooctanoate/perfluorooctane sulfonate-induced senescence of hepatocytes: An integrated computational and experimental analysis
inferred← citeshttps://doi.org/10.1016/j.jtemb.2014.07.010openalex-snapshot
Silencing of the Menkes copper-transporting ATPase (Atp7a) gene increases cyclin D1 protein expression and impairs proliferation of rat intestinal epithelial (IEC-6) cells
inferred← citeshttps://doi.org/10.1016/j.mad.2015.01.002openalex-snapshot
Comparison of telomere length between population-specific mitochondrial haplogroups among different age groups in a Latvian population
inferred← citeshttps://doi.org/10.1016/j.mad.2016.05.003openalex-snapshot
Vascular ageing and endothelial cell senescence: Molecular mechanisms of physiology and diseases
inferred← citeshttps://doi.org/10.1016/j.mad.2016.05.004openalex-snapshot
Role of NOX2 in mediating doxorubicin-induced senescence in human endothelial progenitor cells
inferred← citeshttps://doi.org/10.1016/j.mad.2016.05.006openalex-snapshot
DNA damage in the oligodendrocyte lineage and its role in brain aging
inferred← citeshttps://doi.org/10.1016/j.mad.2019.04.006openalex-snapshot
Oxidative stress-induced senescence markedly increases disc cell bioenergetics
inferred← citeshttps://doi.org/10.1016/j.mad.2021.111478openalex-snapshot
The biological relevance of pigment epithelium-derived factor on the path from aging to age-related disease
inferred← citeshttps://doi.org/10.1016/j.mad.2024.111936openalex-snapshot
SuperAgers and centenarians, dynamics of healthy ageing with cognitive resilience
showing the first 200 of 787 · page through all 787
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.