On the public citation graph

Differentiation fate of a stem-like CD4 T cell controls immunity to cancer

https://doi.org/10.1038/s41586-024-08076-7

0 signed · 111 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ijc.25429openalex-snapshot

Regulatory T cells in tumor immunity

inferredcites →https://doi.org/10.1016/j.cell.2016.12.022openalex-snapshot

Systemic Immunity Is Required for Effective Cancer Immunotherapy

inferredcites →https://doi.org/10.1016/j.cell.2017.07.024openalex-snapshot

Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade

inferredcites →https://doi.org/10.1016/j.cell.2019.02.005openalex-snapshot

Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity

inferredcites →https://doi.org/10.1016/j.cell.2021.04.048openalex-snapshot

Integrated analysis of multimodal single-cell data

inferredcites →https://doi.org/10.1016/j.cell.2021.11.007openalex-snapshot

Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses

inferredcites →https://doi.org/10.1016/j.cell.2023.03.006openalex-snapshot

Immune checkpoint therapy—current perspectives and future directions

inferredcites →https://doi.org/10.1016/j.crmeth.2022.100200openalex-snapshot

Interactive, integrated analysis of single-cell transcriptomic and phylogenetic data with PhyloVision

inferredcites →https://doi.org/10.1016/j.immuni.2009.05.001openalex-snapshot

Plasticity of CD4+ T Cell Lineage Differentiation

inferredcites →https://doi.org/10.1016/j.immuni.2018.12.021openalex-snapshot

Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy

inferredcites →https://doi.org/10.1016/j.immuni.2022.05.003openalex-snapshot

BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen

inferredcites →https://doi.org/10.1016/j.immuni.2022.12.002openalex-snapshot

CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor

inferredcites →https://doi.org/10.1038/nature04444openalex-snapshot

Restoring function in exhausted CD8 T cells during chronic viral infection

inferredcites →https://doi.org/10.1038/nature14011openalex-snapshot

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

inferredcites →https://doi.org/10.1038/nature19330openalex-snapshot

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy

inferredcites →https://doi.org/10.1038/ni.3331openalex-snapshot

CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors

inferredcites →https://doi.org/10.1038/ni1428openalex-snapshot

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

inferredcites →https://doi.org/10.1038/nmeth.3364openalex-snapshot

MiXCR: software for comprehensive adaptive immunity profiling

inferredcites →https://doi.org/10.1038/s41422-018-0011-0openalex-snapshot

A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy

inferredcites →https://doi.org/10.1038/s41467-018-04524-xopenalex-snapshot

Induction of anergic or regulatory tumor-specific CD4+ T cells in the tumor-draining lymph node

inferredcites →https://doi.org/10.1038/s41577-018-0044-0openalex-snapshot

CD4+ T cell help in cancer immunology and immunotherapy

inferredcites →https://doi.org/10.1038/s41586-019-1244-xopenalex-snapshot

Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation

inferredcites →https://doi.org/10.1038/s41586-019-1326-9openalex-snapshot

TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection

inferredcites →https://doi.org/10.1038/s41586-019-1836-5openalex-snapshot

An intra-tumoral niche maintains and differentiates stem-like CD8 T cells

inferredcites →https://doi.org/10.1038/s41586-021-03862-zopenalex-snapshot

Functional HPV-specific PD-1+ stem-like CD8 T cells in head and neck cancer

inferredcites →https://doi.org/10.1038/s41586-021-04248-xopenalex-snapshot

An autoimmune stem-like CD8 T cell population drives type 1 diabetes

inferredcites →https://doi.org/10.1038/s41586-022-04916-6openalex-snapshot

Immune tolerance of food is mediated by layers of CD4+ T cell dysfunction

inferredcites →https://doi.org/10.1038/s41590-023-01682-zopenalex-snapshot

CD4+ T cell immunity is dependent on an intrinsic stem-like program

inferredcites →https://doi.org/10.1038/s41590-024-01803-2openalex-snapshot

TCF1–LEF1 co-expression identifies a multipotent progenitor cell (TH2-MPP) across human allergic diseases

inferredcites →https://doi.org/10.1038/s41591-023-02345-0openalex-snapshot

Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma

inferredcites →https://doi.org/10.1038/s41592-019-0667-5openalex-snapshot

NicheNet: modeling intercellular communication by linking ligands to target genes

inferredcites →https://doi.org/10.1038/s43018-022-00338-5openalex-snapshot

The interaction of CD4+ helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response

inferredcites →https://doi.org/10.1038/s43018-023-00521-2openalex-snapshot

CD4+ T cells in cancer

inferredcites →https://doi.org/10.1084/jem.20061852openalex-snapshot

Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease

inferredcites →https://doi.org/10.1084/jem.20130579openalex-snapshot

Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma

inferredcites →https://doi.org/10.1084/jem.20141518openalex-snapshot

ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis

inferredcites →https://doi.org/10.1084/jem.20172335openalex-snapshot

Effector CD4 T cells with progenitor potential mediate chronic intestinal inflammation

inferredcites →https://doi.org/10.1084/jem.20180684openalex-snapshot

High-dimensional single cell analysis identifies stem-like cytotoxic CD8+ T cells infiltrating human tumors

inferredcites →https://doi.org/10.1084/jem.20210749openalex-snapshot

In vivo labeling reveals continuous trafficking of TCF-1+ T cells between tumor and lymphoid tissue

inferredcites →https://doi.org/10.1093/nar/gkz365openalex-snapshot

CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing

inferredcites →https://doi.org/10.1126/science.1129139openalex-snapshot

Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome

inferredcites →https://doi.org/10.1126/science.1203486openalex-snapshot

Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion

inferredcites →https://doi.org/10.1126/sciimmunol.abg7836openalex-snapshot

A reservoir of stem-like CD8 + T cells in the tumor-draining lymph node preserves the ongoing antitumor immune response

inferredcites →https://doi.org/10.1128/jvi.68.12.8056-8063.1994openalex-snapshot

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

inferredcites →https://doi.org/10.1146/annurev-immunol-030409-101212openalex-snapshot

Differentiation of Effector CD4 T Cell Populations

inferredcites →https://doi.org/10.1159/000444256openalex-snapshot

Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis

inferredcites →https://doi.org/10.1159/000453569openalex-snapshot

PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.5126088openalex-extracted

Antigen-Specific Profiling Identifies T-bet-Expressing Melanoma-Specific CD8 T Cells Associated with Pathologic Response to Neoadjuvant Anti-PD-1

inferred← citeshttps://doi.org/10.1002/adhm.202503771openalex-snapshot

Engineered Immunoagonist Non‐Coding RNA (incRNA) Activates Dual TLR Pathways for Cancer Immunotherapy

inferred← citeshttps://doi.org/10.1002/advs.202508692openalex-snapshot

Insights into the Mechanisms of Immune‐Checkpoint Inhibitors Gained from Spatiotemporal Dynamics of the Tumor Microenvironment

inferred← citeshttps://doi.org/10.1002/brb3.70811openalex-snapshot

The Mediation of Circulating Inflammatory Proteins in the Causal Pathway From Immune Cells to Delirium

inferred← citeshttps://doi.org/10.1002/pros.70102openalex-snapshot

Deciphering Resistance: Beyond the Androgen Paradigm; Report From the 2025 Coffey‐Holden Prostate Cancer Academy Meeting

inferred← citeshttps://doi.org/10.1007/978-981-95-9598-3_13openalex-snapshot

Immune Evasion Mechanisms of H. pylori

inferred← citeshttps://doi.org/10.1007/s00240-025-01830-0openalex-snapshot

Unraveling the gut–immune–kidney axis in kidney stone disease: a two-step Mendelian randomization investigation

inferred← citeshttps://doi.org/10.1007/s10856-025-06986-0openalex-snapshot

Evaluation of cellular immune response and biosafety of SV40 virus-like particle in tumor immunotherapy

inferred← citeshttps://doi.org/10.1016/bs.mcb.2026.02.025openalex-snapshot

In vitro expansion of stem-like memory T cells via D-mannose supplementation

inferred← citeshttps://doi.org/10.1016/j.ccell.2025.02.021openalex-snapshot

An innovative ALA-CART platform exhibits high efficacy against cancers

inferred← citeshttps://doi.org/10.1016/j.ccell.2025.12.004openalex-snapshot

Antigen-specific profiling identifies T-bet+ melanoma-specific CD8+ T cells associated with response to neoadjuvant PD-1 blockade

inferred← citeshttps://doi.org/10.1016/j.ccell.2026.05.007openalex-snapshot

Hypoxia shapes both therapeutic response and resistance in metastatic clear cell renal cell carcinoma

inferred← citeshttps://doi.org/10.1016/j.celrep.2026.117296openalex-snapshot

Requirements for development of T helper 1 and T follicular helper cells from a common precursor

inferred← citeshttps://doi.org/10.1016/j.chembiol.2026.02.011openalex-snapshot

Oxidizing to optimize stemness and antitumor immunity

inferred← citeshttps://doi.org/10.1016/j.imlet.2026.107143openalex-snapshot

Molecular requirements of pathogenic Th2 cell differentiation in allergic airway disease

inferred← citeshttps://doi.org/10.1016/j.immuni.2026.03.008openalex-snapshot

Acute and chronic infections drive distinct trajectories in human memory CD4+ T cell formation

inferred← citeshttps://doi.org/10.1016/j.immuni.2026.06.001openalex-snapshot

Stem-like precursors of exhausted Th cells upheld by a Tox-Myb-Eomes transcriptional hierarchy propagate Th cell responses in chronic infection

inferred← citeshttps://doi.org/10.1016/j.immuni.2026.06.017openalex-snapshot

CD4+ T cells persist with their Eomes

inferred← citeshttps://doi.org/10.1016/j.jddst.2026.108423openalex-snapshot

Clinical-oriented strategies in intraperitoneal therapy: Drug delivery systems for precision treatment of peritoneal metastases

inferred← citeshttps://doi.org/10.1016/j.phymed.2025.157198openalex-snapshot

Yuzhi Zhixue Granules regulate the JAK/STAT pathway to affect T-cell differentiation in the colon of ulcerative colitis

inferred← citeshttps://doi.org/10.1016/j.stem.2025.12.010openalex-snapshot

Tunable differentiation of human CD4+ and CD8+ T cells from pluripotent stem cells

inferred← citeshttps://doi.org/10.1016/j.tcb.2025.06.004openalex-snapshot

Stem-like cells at the center of CD4 T cell differentiation

inferred← citeshttps://doi.org/10.1016/j.trecan.2025.09.004openalex-snapshot

Reprogramming T cell stemness against cancer

inferred← citeshttps://doi.org/10.1016/j.ymthe.2025.09.047openalex-snapshot

BiTE-secreting T cells rationally combine with PD-1 blockade and vaccine boosting to reshape antitumor immunity in ovarian cancer

inferred← citeshttps://doi.org/10.1038/s41392-026-02858-3openalex-snapshot

Tumor-draining lymph nodes shape the tumor microenvironment through enrichment of tumor-reactive effector-exhausted CD8+ T cells

inferred← citeshttps://doi.org/10.1038/s41401-026-01845-2openalex-snapshot

Targeting BCL9/BCL9L enhances CD4+ T cell-mediated Th1 antitumor immunity through activation of STAT1/STAT4 signaling

inferred← citeshttps://doi.org/10.1038/s41418-025-01490-yopenalex-snapshot

SIRT7 regulates T-cell antitumor immunity through modulation BCAA and fatty acid metabolism

inferred← citeshttps://doi.org/10.1038/s41423-025-01321-7openalex-snapshot

Beyond T-cell subsets: stemness and adaptation redefining immunity and immunotherapy

inferred← citeshttps://doi.org/10.1038/s41467-025-59341-wopenalex-snapshot

Mature tertiary lymphoid structures evoke intra-tumoral T and B cell responses via progenitor exhausted CD4+ T cells in head and neck cancer

inferred← citeshttps://doi.org/10.1038/s41467-025-65048-9openalex-snapshot

β-adrenergic signaling blockade attenuates metastasis through activation of cytotoxic CD4 T cells

inferred← citeshttps://doi.org/10.1038/s41467-026-69671-yopenalex-snapshot

High efficiency CRISPR knock-in demonstrates that TCF1 is insufficient to reverse T cell exhaustion

inferred← citeshttps://doi.org/10.1038/s41467-026-74255-xopenalex-snapshot

Dynamic immune profiling predicts response to radiation plus anti-PD-1 therapy in oligometastatic renal cell carcinoma

inferred← citeshttps://doi.org/10.1038/s41586-026-11066-6openalex-snapshot

A preinvasive regulatory T cell axis for lung cancer interception

inferred← citeshttps://doi.org/10.1038/s41590-026-02451-4openalex-snapshot

Tissue-specific clonal selection and differentiation of CD4⁺ T cells during infection

inferred← citeshttps://doi.org/10.1038/s41590-026-02453-2openalex-snapshot

TOX drives CD4+ TH1 effector function, antitumor immunity and autoimmune pathology

inferred← citeshttps://doi.org/10.1038/s42256-025-01081-zopenalex-snapshot

Mapping T helper cell targets with deep learning

inferred← citeshttps://doi.org/10.1073/pnas.2522928123openalex-snapshot

Stepwise differentiation from precursor intermediates and distinct Th1 checkpoints promote CD4 Th1 cell differentiation during chronic viral infection

inferred← citeshttps://doi.org/10.1084/jem.20241417openalex-snapshot

CD4+ T cell dysfunction in cancer

inferred← citeshttps://doi.org/10.1101/2024.12.31.630523openalex-snapshot

Acquisition of discrete immune suppressive barriers contributes to the initiation and progression of preinvasive to invasive human lung cancer

inferred← citeshttps://doi.org/10.1101/2025.04.11.648467openalex-snapshot

Tissue-wide profiling of human lungs reveals spatial sequestration of macrophages in tuberculosis

inferred← citeshttps://doi.org/10.1101/2025.08.22.671704openalex-snapshot

CD4 memory T cells orchestrate therapy-responsive immune niches in colorectal cancer liver metastases

inferred← citeshttps://doi.org/10.1101/2025.08.25.672130openalex-snapshot

Tissue-specific clonal selection and differentiation of CD4⁺ T cells during infection

inferred← citeshttps://doi.org/10.1101/2025.09.17.674622openalex-snapshot

Common origin for effector and regulatory follicular and tissue-Adapted CD4+ T cells in Non-Small Cell Lung Cancer

inferred← citeshttps://doi.org/10.1111/jcmm.71235openalex-snapshot

Immune Landscape and Tumour Heterogeneity in Ovarian Cancer: Insights From Single‐Cell RNA Sequencing

inferred← citeshttps://doi.org/10.1126/sciadv.ady6423openalex-snapshot

A distinct subset of stem-cell memory is poised for the cytotoxicity program in CD4 + T cells in humans

inferred← citeshttps://doi.org/10.1126/sciadv.aeg2679openalex-snapshot

H3.3 chaperone Hira primes the effector program and function of regulatory T cells

inferred← citeshttps://doi.org/10.1126/science.ads7910openalex-snapshot

CD4 + T cells impair tumor growth through IL-3 and TNF-dependent vascular damage

inferred← citeshttps://doi.org/10.1126/sciimmunol.adz4302openalex-snapshot

T reg cells promote immunotherapy-induced immune evasion by restraining CD4 T cell control of MHC-I–deficient metastatic pancreatic cancer

inferred← citeshttps://doi.org/10.1126/sciimmunol.aec3133openalex-snapshot

Single-cell TCR mapping reveals spatially coordinated T cell states in head and neck cancer

inferred← citeshttps://doi.org/10.1136/gutjnl-2025-337038openalex-snapshot

SPP1 + macrophages facilitate the differentiation and maturation of regulatory T cells in tumour-draining lymph nodes of colorectal cancer

inferred← citeshttps://doi.org/10.1136/jitc-2025-011859openalex-snapshot

Plasticity of tumor cell immunogenicity: is it druggable?

inferred← citeshttps://doi.org/10.1136/jitc-2025-013636openalex-snapshot

Specific depletion of TIGIT high CD226 − clonally expanded intratumoral Tregs defines safe and effective TIGIT targeting

inferred← citeshttps://doi.org/10.1136/jitc-2025-014620openalex-snapshot

FAP-CD40 and PD1-IL2v combination therapy reprograms immunologically cold tumors through de novo intratumoral T cell-dendritic cell clusters

inferred← citeshttps://doi.org/10.1158/2326-6066.cir-25-0256openalex-snapshot

Removal of Interstitial Hyaluronan Facilitates Subcutaneous Administration and Lymphatic Delivery of Anti-CTLA4 and Improves Antitumor Efficacy

inferred← citeshttps://doi.org/10.1186/s12893-026-03908-xopenalex-snapshot

Predicting PPOI secondary to laparoscopic radical resection of rectal cancer combined with lobaplatin hyperthermic intraperitoneal chemotherapy: a multi-center study

inferred← citeshttps://doi.org/10.1186/s13287-026-04994-7openalex-snapshot

Preclinical efficacy of combination therapy with allogeneic induced pluripotent stem cell-derived invariant natural killer T and α-galactosylceramide-pulsed antigen-presenting cells

inferred← citeshttps://doi.org/10.3389/fgene.2025.1588941openalex-snapshot

Reduced T-Cell stemness underlies Th17 expansion and graft dysfunction in kidney transplant recipients

inferred← citeshttps://doi.org/10.3389/fimmu.2026.1777816openalex-snapshot

Harnessing the immune system: future directions in cancer immunotherapy

inferred← citeshttps://doi.org/10.3389/fimmu.2026.1853163openalex-snapshot

Stem-like CD4 T cells in tumors: an emerging framework for antitumor immunity

inferred← citeshttps://doi.org/10.3390/ijms26052311openalex-snapshot

Characterization of Exhausted T Cell Signatures in Pan-Cancer Settings

inferred← citeshttps://doi.org/10.3390/ph19081284openalex-snapshot

Single-Cell RNA Sequencing Reveals T-Cell Metabolic Activation and SGPL1 as a Candidate Predictor of PD-1 Resistance in Urothelial Carcinoma

inferred← citeshttps://doi.org/10.37349/etat.2025.1002315openalex-snapshot

Harnessing the power of tumor-draining lymph nodes: unveiling predictive biomarkers for immune checkpoint inhibitor

inferred← citeshttps://doi.org/10.64898/2026.01.13.699214openalex-snapshot

Prime-Target neoantigen vaccination unleashes unprecedented T cell immunity within “cold” immunosuppressive tumors

inferred← citeshttps://doi.org/10.64898/2026.06.04.730068openalex-snapshot

Immune repertoire profiling reveals extensive clonal expansion of T and B cells in CXCL9-rich niches in sinonasal cancer

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.