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The Conserved Arginine in Rho-GTPase-Activating Protein Is Essential for Efficient Catalysis but Not for Complex Formation with Rho·GDP and Aluminum Fluoride
Compensatory and Long-Range Changes in Picosecond–Nanosecond Main-Chain Dynamics upon Complex Formation: 15N Relaxation Analysis of the Free and Bound States of the Ubiquitin-like Domain of Human Plexin-B1 and the Small GTPase Rac1
BNIP-Sα induces cell rounding and apoptosis by displacing p50RhoGAP and facilitating RhoA activation via its unique motifs in the BNIP-2 and Cdc42GAP homology domain
Mechanistic Insights into Specificity, Activity, and Regulatory Elements of the Regulator of G-protein Signaling (RGS)-containing Rho-specific Guanine Nucleotide Exchange Factors (GEFs) p115, PDZ-RhoGEF (PRG), and Leukemia-associated RhoGEF (LARG)
Gain-of-function p.F28S variant in RAC3 disrupts neuronal differentiation, migration and axonogenesis during cortical development, leading to neurodevelopmental disorder
Pancytopenia, Recurrent Infection, Poor Wound Healing, Heterotopia of the Brain Probably Associated with A Candidate Novel de Novo CDC42 Gene Defect: Expanding the Molecular and Phenotypic Spectrum
Développement de méthodologies innovantes pour la caractérisation d’interfaces protéine-protéine et la conception d’inhibiteurs spécifiques : exploration de l’interface protéique de RhoA /ArhGEF1
Extraction of active RhoGTPases by RhoGDI regulates spatiotemporal patterning of RhoGTPases
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