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An osteopontin splice variant induces anchorage independence in human breast cancer cells

https://doi.org/10.1038/sj.onc.1209248

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Antibodies to different peptides in osteopontin reveal complexities in the various secreted forms

inferredcites →https://doi.org/10.1006/bbrc.1998.9306openalex-snapshot

Detection of Mouse Osteopontin by Western Blotting

inferredcites →https://doi.org/10.1006/cimm.2001.1800openalex-snapshot

Costimulation by Extracellular Matrix Proteins Determines the Response to TCR Ligation

inferredcites →https://doi.org/10.1006/excr.1998.4029openalex-snapshot

The LCC15-MB Human Breast Cancer Cell Line Expresses Osteopontin and Exhibits an Invasive and Metastatic Phenotype

inferredcites →https://doi.org/10.1007/s001090000138openalex-snapshot

Stress response genes: the genes that make cancer metastasize

inferredcites →https://doi.org/10.1016/0092-8674(91)90403-lopenalex-snapshot

A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells

inferredcites →https://doi.org/10.1016/0140-6736(92)93077-zopenalex-snapshot

Significance of CD44 gene products for cancer diagnosis and disease evaluation

inferredcites →https://doi.org/10.1016/0169-6009(91)90071-7openalex-snapshot

Differential regulation of the 55 and 44 kDa forms of secreted phosphoprotein 1 (SPP-1, osteopontin) in normal and transformed rat bone cells by osteotropic hormones, growth factors and a tumor promoter

inferredcites →https://doi.org/10.1016/0888-7543(90)90191-vopenalex-snapshot

cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN)

inferredcites →https://doi.org/10.1016/1074-7613(95)90144-2openalex-snapshot

A signaling pathway coupled to T cell receptor ligation by MMTV superantigen leading to transient activation and programmed cell death

inferredcites →https://doi.org/10.1016/j.taap.2003.09.002openalex-snapshot

Expression of genes in the TGF-β signaling pathway is significantly deregulated in smooth muscle cells from aorta of aryl hydrocarbon receptor knockout mice

inferredcites →https://doi.org/10.1016/s0021-9258(17)42407-0openalex-snapshot

Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in mouse kidney epithelial cells.

inferredcites →https://doi.org/10.1016/s0021-9258(18)82107-xopenalex-snapshot

Comparative analysis of two alternative first exons reported for the mouse osteopontin gene

inferredcites →https://doi.org/10.1016/s0361-9230(00)00379-8openalex-snapshot

Molecular mechanisms of tumor dissemination in primary and metastatic brain cancers

inferredcites →https://doi.org/10.1038/sj.onc.1200993openalex-snapshot

Isolation of and effector for metastasis-inducing DNAs from a human metastatic carcinoma cell line

inferredcites →https://doi.org/10.1038/sj.onc.1202799openalex-snapshot

Osteopontin induces increased invasiveness and plasminogen activator expression of human mammary epithelial cells

inferredcites →https://doi.org/10.1038/sj.onc.1204358openalex-snapshot

Regulatory region of metastasis-inducing DNA is the binding site for T cell factor-4

inferredcites →https://doi.org/10.1046/j.1432-1033.2003.03574.xopenalex-snapshot

Phosphorylation of NF‐κB proteins by cyclic GMP‐dependent kinase

inferredcites →https://doi.org/10.1074/jbc.274.51.36328openalex-snapshot

The Integrin α9β1 Binds to a Novel Recognition Sequence (SVVYGLR) in the Thrombin-cleaved Amino-terminal Fragment of Osteopontin

inferredcites →https://doi.org/10.1074/jbc.m109028200openalex-snapshot

Tumor-derived Osteopontin Is Soluble, Not Matrix Associated

inferredcites →https://doi.org/10.1093/bioinformatics/btf877openalex-snapshot

Identifying differentially expressed genes using false discovery rate controlling procedures

inferredcites →https://doi.org/10.1093/nar/17.8.3306openalex-snapshot

The cDNA and derived amino acid sequence for human osteopontin

inferredcites →https://doi.org/10.1097/00000658-199510000-00007openalex-snapshot

Restoration of CD44H Expression in Colon Carcinomas Reduces Tumorigenicity

inferredcites →https://doi.org/10.1111/j.1749-6632.1995.tb44625.xopenalex-snapshot

Osteopontin‐Induced Modifications of Cellular Functionsa

inferredcites →https://doi.org/10.1111/j.1749-6632.1996.tb52678.xopenalex-snapshot

IL‐12‐Engineered Dendritic Cells Serve as Effective Tumor Vaccine Adjuvants in Vivoa

inferredcites →https://doi.org/10.1111/j.1749-6632.1996.tb52683.xopenalex-snapshot

Tumor Cells Transfected with B7‐1 and Interleukin‐12 cDNA Induce Protective Immunity

inferredcites →https://doi.org/10.1111/j.2517-6161.1995.tb02031.xopenalex-snapshot

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

inferredcites →https://doi.org/10.1114/1.1497383openalex-snapshot

Homotypic Interactions of Soluble and Immobilized Osteopontin

inferredcites →https://doi.org/10.1126/science.271.5248.509openalex-snapshot

Receptor-Ligand Interaction Between CD44 and Osteopontin (Eta-1)

inferredcites →https://doi.org/10.1126/science.287.5454.860openalex-snapshot

Eta-1 (Osteopontin): An Early Component of Type-1 (Cell-Mediated) Immunity

inferredcites →https://doi.org/10.1128/jvi.53.3.841-850.1985openalex-snapshot

Altered processing of a major secreted phosphoprotein correlates with tumorigenicity in Rous sarcoma virus-transformed mammalian cells

inferredcites →https://doi.org/10.1128/mcb.23.18.6507-6519.2003openalex-snapshot

Growth Factor Signaling Induces Metastasis Genes in Transformed Cells: Molecular Connection between Akt Kinase and Osteopontin in Breast Cancer

inferredcites →https://doi.org/10.1186/gb-2003-4-10-r70openalex-snapshot

Identifying biological themes within lists of genes with EASE

inferredcites →https://doi.org/10.1186/gb-2003-4-6-p4openalex-snapshot

Identifying biological themes within lists of genes with EASE

inferredcites →https://doi.org/10.1189/jlb.68.4.495openalex-snapshot

Osteopontin augments CD3-mediated interferon-γ and CD40 ligand expression by T cells, which results in IL-12 production from peripheral blood mononuclear cells

inferredcites →https://doi.org/10.1189/jlb.72.4.752openalex-snapshot

Phosphorylation-dependent interaction of osteopontin with its receptors regulates macrophage migration and activation

inferredcites →https://doi.org/10.1201/9781482298185openalex-snapshot

Inflammatory Cells and Mediators in CNS Disease

inferredcites →https://doi.org/10.1242/jcs.111.9.1165openalex-snapshot

Osteopontin is a ligand for the α4β1 integrin

inferredcites →https://doi.org/10.1385/ct:4:1:47openalex-snapshot

Different global gene expression profiles in benzo[a]pyrene-and dioxin-treated vascular smooth muscle cells of AHR-knockout and wild-type mice

inferredcites →https://doi.org/10.2144/04365st02openalex-snapshot

Microarray results improve significantly as hybridization approaches equilibrium

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Specifically modified osteopontin in rheumatoid arthritis fibroblast‐like synoviocytes supports interaction with B cells and enhances production of interleukin‐6

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Tumor-derived microparticles induce bone marrow-derived cell mobilization and tumor homing: A process regulated by osteopontin

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Metabolism in cancer metastasis

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Osteopontin overexpression in breast cancer: Knowledge gained and possible implications for clinical management

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The osteopontin-c splice junction is important for anchorage-independent growth

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Plasma osteopontin in comparison with bone markers as indicator of bone metastasis and survival outcome in patients with prostate cancer

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Both osteopontin‐c and osteopontin‐b splicing isoforms exert pro‐tumorigenic roles in prostate cancer cells

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Osteopontin Signaling in Shaping Tumor Microenvironment Conducive to Malignant Progression

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Role of Osteopontin in Tumor Microenvironment: A New Paradigm in Cancer Therapy

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Introduction of a new critical p value correction method for statistical significance analysis of metabonomics data

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CRISPR/Cas9 mediated knocking out of OPN gene enhances radiosensitivity in MDA-MB-231 breast cancer cell line

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Differential osteopontin expression in human osteoblasts derived from iliac crest and alveolar bone and its role in early stages of angiogenesis

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Interactions between breast cancer cells and bone marrow derived cells in vitro define a role for osteopontin in affecting breast cancer cell migration

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Intracellular osteopontin (iOPN) and immunity

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Intranasal Delivery of RGD Motif-Containing Osteopontin Icosamer Confers Neuroprotection in the Postischemic Brain via αvβ3 Integrin Binding

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Pre- and post-translational regulation of osteopontin in cancer

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Osteopontin splice variants expression is involved on docetaxel resistance in PC3 prostate cancer cells

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Bone niche and bone metastases

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Osteopontin Promotes the Invasive Growth of Melanoma Cells by Activating Integrin αvβ3 and Down-Regulating Tetraspanin CD9

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Osteopontin – A multi-modal marker and mediator in atherosclerotic vascular disease

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CRISPR-based therapeutic targeting of signaling pathways in breast cancer

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Osteopontin splice variants and polymorphisms in cancer progression and prognosis

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SPP1 as a central mediator in the tumor microenvironment: Orchestrating cellular crosstalk, immune evasion, and therapy resistance

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Tumorigenic properties of alternative osteopontin isoforms in mesothelioma

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Prognostic values of osteopontin-c, E-cadherin and β-catenin in breast cancer

inferred← citeshttps://doi.org/10.1016/j.canlet.2008.04.030openalex-snapshot

Molecular mechanisms of metastasis

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Human osteopontin splicing isoforms: Known roles, potential clinical applications and activated signaling pathways

inferred← citeshttps://doi.org/10.1016/j.canlet.2013.10.008openalex-snapshot

Osteopontin-a alters glucose homeostasis in anchorage-independent breast cancer cells

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RNA binding proteins: Linking mechanotransduction and tumor metastasis

inferred← citeshttps://doi.org/10.1016/j.critrevonc.2013.08.013openalex-snapshot

Bone sialoprotein and osteopontin in bone metastasis of osteotropic cancers

inferred← citeshttps://doi.org/10.1016/j.cytogfr.2008.08.001openalex-snapshot

Osteopontin: Role in immune regulation and stress responses

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Protein deregulation associated with breast cancer metastasis

inferred← citeshttps://doi.org/10.1016/j.gene.2016.09.031openalex-snapshot

microRNAs target SRSF7 splicing factor to modulate the expression of osteopontin splice variants in renal cancer cells

inferred← citeshttps://doi.org/10.1016/j.heliyon.2022.e12359openalex-snapshot

Serum protein profiling of lung, pancreatic, and colorectal cancers reveals alcohol consumption-mediated disruptions in early-stage cancer detection

inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e21055openalex-snapshot

Role of osteopontin in cancer development and treatment

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Association of increased osteopontin and splice variant-c mRNA expression with HER2 and triple-negative/basal-like breast carcinomas subtypes and recurrence

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Suppression of tumor growth in xenograft model mice by small interfering RNA targeting osteopontin delivery using biocompatible poly(amino ester)

inferred← citeshttps://doi.org/10.1016/j.leukres.2012.02.016openalex-snapshot

Interleukin-6, osteopontin and Raf/MEK/ERK signaling modulate the sensitivity of human myeloma cells to alkylphosphocholines

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Osteopontin-c is overexpressed in KMT2A-AFF1 positive pediatric B-cell lymphoblastic leukemia when compared to those with ETV6-RUNX1”

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Role of osteopontin in the pathophysiology of cancer

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The alternative matrisome: Alternative splicing of ECM proteins in development, homeostasis and tumor progression

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Small Integrin binding Ligand N-linked Glycoproteins, prostate-specific antigen and time to prostate cancer diagnosis

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Expression and localization of osteopontin, homing cell adhesion molecule/CD44, and integrin αvβ3 in pleomorphic adenoma, polymorphous low-grade adenocarcinoma, and adenoid cystic carcinoma

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Osteopontin and breast cancer metastasis: Possible role of genistein on the regulation of osteopontin

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The crucial role of SPP1 in osteoporosis, osteoarthritis, and cancer

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Expression of a prometastatic splice variant of osteopontin, OPNC, in human pancreatic ductal adenocarcinoma

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Alterations in gene expression in cultured human cells after acute exposure to uranium salt: Involvement of a mineralization regulator

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Expression analysis of osteopontin mRNA splice variants in prostate cancer and benign prostatic hyperplasia

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Basic science (April 2006)

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The Metastasis-Associated Extracellular Matrix Protein Osteopontin Forms Transient Structure in Ligand Interaction Sites

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Nuclear osteopontin-c is a prognostic breast cancer marker

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Influence of osteopontin expression on the metastatic growth of CC531 rat colorectal carcinoma cells in rat liver

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Osteopontin splice variants expressed by breast tumors regulate monocyte activation via MCP-1 and TGF-β1

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Proangiogenic functions of an RGD-SLAY-containing osteopontin icosamer peptide in HUVECs and in the postischemic brain

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Immune microenvironment of gliomas

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BMI1 cooperates with H-RAS to induce an aggressive breast cancer phenotype with brain metastases

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Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion

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Breast cancer risk in premalignant lesions: osteopontin splice variants indicate prognosis

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Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasing osteopontin and Stat3 signaling

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Alternative splicing variant of the hypoxia marker carbonic anhydrase IX expressed independently of hypoxia and tumour phenotype

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An osteopontin fragment is essential for tumor cell invasion in hepatocellular carcinoma

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Enhanced OXPHOS, glutaminolysis and β-oxidation constitute the metastatic phenotype of melanoma cells

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Osteopontin Undergoes Polymerization in Vivo and Gains Chemotactic Activity for Neutrophils Mediated by Integrin α9β1

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Verifying expressed transcript variants by detecting and assembling stretches of consecutive exons

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Expression pattern of osteopontin splice variants and its functions on cell apoptosis and invasion in glioma cells

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Thrombospondin 1 binding to calreticulin‐LRP1 signals resistance to anoikis

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Functional Heterogeneity of Osteopontin Isoforms in Non-small Cell Lung Cancer

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The effect of in vitro photodynamic therapy on increase of osteopontin and heat shock protein 70 expression in squamous cell and colon carcinoma

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Intravital Förster resonance energy transfer imaging reveals osteopontin‐mediated polymorphonuclear leukocyte activation by tumor cell emboli

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Expression pattern of osteopontin isoforms in malignant melanoma cell lines

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Osteopontin expression in healing wounds of horses and in human keloids

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Osteopontin/secreted phosphoprotein‐1 harnesses glial‐, immune‐, and neuronal cell ligand‐receptor interactions to sense and regulate acute and chronic neuroinflammation

inferred← citeshttps://doi.org/10.1111/j.1349-7006.2010.01561.xopenalex-snapshot

Osteopontin can act as an effector for a germline mutation of BRCA1 in malignant transformation of breast cancer‐related cells

inferred← citeshttps://doi.org/10.1111/j.1471-4159.2007.04858.xopenalex-snapshot

A novel biological function for CD44 in axon growth of retinal ganglion cells identified by a bioinformatics approach

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Down‐regulation of osteopontin attenuates breast tumour progression in vivo

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Spheroid‐forming subpopulation of breast cancer cells demonstrates vasculogenic mimicry via hsa‐miR‐299–5p regulated de novo expression of osteopontin

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Role of the metastasis‐promoting protein osteopontin in the tumour microenvironment

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Osteopontin splice variant as a potential marker for metastatic disease in pancreatic adenocarcinoma

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WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape

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Prognostic Value of Osteopontin Splice Variant-c Expression in Breast Cancers: A Meta-Analysis

inferred← citeshttps://doi.org/10.1155/2016/7675437openalex-snapshot

Osteopontin Bridging Innate and Adaptive Immunity in Autoimmune Diseases

inferred← citeshttps://doi.org/10.1158/1541-7786.mcr-10-0463openalex-snapshot

Osteopontin-c Splicing Isoform Contributes to Ovarian Cancer Progression

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Elevated tumor and serum levels of the hypoxia-associated protein osteopontin are associated with prognosis for soft tissue sarcoma patients

inferred← citeshttps://doi.org/10.1186/1471-2407-12-131openalex-snapshot

Prognostic impact of mRNA levels of osteopontin splice variants in soft tissue sarcoma patients

inferred← citeshttps://doi.org/10.1186/1471-2407-8-38openalex-snapshot

Development of fragment-specific osteopontin antibodies and ELISA for quantification in human metastatic breast cancer

inferred← citeshttps://doi.org/10.1186/2193-1801-2-110openalex-snapshot

RNA blood levels of osteopontin splice variants are cancer markers

inferred← citeshttps://doi.org/10.1186/2251-6581-13-13openalex-snapshot

Tertiary structure prediction and identification of druggable pocket in the cancer biomarker – Osteopontin-c

inferred← citeshttps://doi.org/10.1186/bcr2199openalex-snapshot

Osteopontin: a new role for a familiar actor

inferred← citeshttps://doi.org/10.1186/s12859-015-0827-2openalex-snapshot

PC-TraFF: identification of potentially collaborating transcription factors using pointwise mutual information

inferred← citeshttps://doi.org/10.1186/s12885-023-10854-xopenalex-snapshot

Meta-analysis of Osteopontin splice variants in cancer

inferred← citeshttps://doi.org/10.1186/s12943-023-01744-8openalex-snapshot

Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments

inferred← citeshttps://doi.org/10.1186/s12964-023-01183-4openalex-snapshot

Anoikis resistance––protagonists of breast cancer cells survive and metastasize after ECM detachment

inferred← citeshttps://doi.org/10.1186/s12974-014-0197-0openalex-snapshot

The effect of osteopontin and osteopontin-derived peptides on preterm brain injury

inferred← citeshttps://doi.org/10.1186/s13058-022-01561-9openalex-snapshot

Breast cancer risk in papilloma patients: Osteopontin splice variants indicate prognosis

inferred← citeshttps://doi.org/10.1186/s13104-022-06179-wopenalex-snapshot

Expression of osteopontin-5 splice variant in the mouse primary and metastatic breast cancer cells

inferred← citeshttps://doi.org/10.1210/en.2007-1312openalex-snapshot

Osteopontin Expression in Human and Murine Obesity: Extensive Local Up-Regulation in Adipose Tissue but Minimal Systemic Alterations

inferred← citeshttps://doi.org/10.1309/ajcp6f2vndamsulaopenalex-snapshot

Osteopontin Regulates VEGFA and ICAM-1 mRNA Expression in Breast Carcinoma

inferred← citeshttps://doi.org/10.1371/journal.pone.0009633openalex-snapshot

The RGD Domain of Human Osteopontin Promotes Tumor Growth and Metastasis through Activation of Survival Pathways

inferred← citeshttps://doi.org/10.1371/journal.pone.0029629openalex-snapshot

Pseudomonas aeruginosa PilY1 Binds Integrin in an RGD- and Calcium-Dependent Manner

inferred← citeshttps://doi.org/10.1371/journal.pone.0056533openalex-snapshot

Expression of Osteopontin in Patients with Thyroid Dysfunction

inferred← citeshttps://doi.org/10.1371/journal.pone.0105675openalex-snapshot

Energy Metabolism during Anchorage-Independence. Induction by Osteopontin-c

inferred← citeshttps://doi.org/10.1371/journal.pone.0160412openalex-snapshot

Osteopontin Fragments with Intact Thrombin-Sensitive Site Circulate in Cervical Cancer Patients

inferred← citeshttps://doi.org/10.1371/journal.pone.0297695openalex-snapshot

TIM3 activates the ERK1/2 pathway to promote invasion and migration of thyroid tumors

inferred← citeshttps://doi.org/10.1515/bmc-2016-0004openalex-snapshot

Embracing the complexity of matricellular proteins: the functional and clinical significance of splice variation

inferred← citeshttps://doi.org/10.1517/14728222.11.1.81openalex-snapshot

Osteopontin: an emerging therapeutic target for anticancer therapy

inferred← citeshttps://doi.org/10.1517/14728222.2011.594438openalex-snapshot

Osteopontin: a potentially important therapeutic target in cancer

inferred← citeshttps://doi.org/10.1517/14728222.2014.925447openalex-snapshot

Osteopontin as a therapeutic target for cancer

inferred← citeshttps://doi.org/10.1530/eje-15-0577openalex-snapshot

Osteopontin expression is correlated with differentiation and good prognosis in medullary thyroid carcinoma

inferred← citeshttps://doi.org/10.15407/exp-oncology.2024.04.333openalex-snapshot

Expression Patterns of Matricellular Proteins in Metastatic Breast Cancer at the Background of Metabolic Syndrome

inferred← citeshttps://doi.org/10.1593/neo.121164openalex-snapshot

Vitamin D Metabolism and Effects on Pluripotency Genes and Cell Differentiation in Testicular Germ Cell Tumors In Vitro and In Vivo

inferred← citeshttps://doi.org/10.1593/neo.81622openalex-snapshot

Inhibition of Breast Cancer Metastasis and Angiogenesis by Antiosteopontin Single-Chain Fv-Fc Fusion Protein

inferred← citeshttps://doi.org/10.18632/oncotarget.10468openalex-snapshot

Osteopontin-a splice variant is overexpressed in papillary thyroid carcinoma and modulates invasive behavior

inferred← citeshttps://doi.org/10.18632/oncotarget.10865openalex-snapshot

Integrin β3 and CD44 levels determine the effects of the OPN-a splicing variant on lung cancer cell growth

inferred← citeshttps://doi.org/10.18632/oncotarget.22240openalex-snapshot

A core program of gene expression characterizes cancer metastases

inferred← citeshttps://doi.org/10.18632/oncotarget.28402openalex-snapshot

Crossroads: the role of biomarkers in the management of lumps in the breast

inferred← citeshttps://doi.org/10.18632/oncotarget.28540openalex-snapshot

Osteopontin induces mitochondrial biogenesis in deadherent cancer cells

inferred← citeshttps://doi.org/10.18632/oncotarget.4161openalex-snapshot

Osteopontin (OPN/SPP1) isoforms collectively enhance tumor cell invasion and dissemination in esophageal adenocarcinoma

inferred← citeshttps://doi.org/10.21203/rs.3.rs-5410549/v1openalex-snapshot

Tumour-derived secreted phosphoprotein 1/SPP1 via activation of microglia contributes to the formation of the breast cancer brain metastatic niche

inferred← citeshttps://doi.org/10.2174/1566523214666141127094033openalex-snapshot

The Potential of the Human Osteopontin Promoter and Single-Nucleotide Polymorphisms for Targeted Cancer Gene Therapy

inferred← citeshttps://doi.org/10.2174/156652410791065381openalex-snapshot

Osteopontin: An Effector and an Effect of Tumor Metastasis

inferred← citeshttps://doi.org/10.22034/apjcp.2017.18.6.1707openalex-snapshot

Osteopontin b and c isoforms: Molecular Candidates Associated with Leukemic Stem Cell Chemoresistance in Acute Myeloid Leukemia

inferred← citeshttps://doi.org/10.2741/2747openalex-snapshot

Pre-mRNA splicing aberrations and cancer

inferred← citeshttps://doi.org/10.2741/3009openalex-snapshot

Osteopontin as a target for cancer therapy

inferred← citeshttps://doi.org/10.31083/j.fbl2811287openalex-snapshot

Anoikis Patterns in Cervical Cancer: Identification of Subgroups and Construction of a Novel Risk Model for Predicting Prognosis and Immune Response

inferred← citeshttps://doi.org/10.3109/1354750x.2011.643485openalex-snapshot

Identification and quantification of osteopontin splice variants in the plasma of lung cancer patients using immunoaffinity capture and targeted mass spectrometry

inferred← citeshttps://doi.org/10.3168/jds.2011-4750openalex-snapshot

Proteomic analysis and immunodetection of the bovine milk osteopontin isoforms

inferred← citeshttps://doi.org/10.3389/fimmu.2021.722170openalex-snapshot

Periostin in Allergy and Inflammation

inferred← citeshttps://doi.org/10.3389/fimmu.2023.1340634openalex-snapshot

Extracellular matrix remodeling in the tumor immunity

inferred← citeshttps://doi.org/10.3389/fmolb.2020.565383openalex-snapshot

The Significance of Secreted Phosphoprotein 1 in Multiple Human Cancers

inferred← citeshttps://doi.org/10.3389/fonc.2016.00257openalex-snapshot

Time and Circumstances: Cancer Cell Metabolism at Various Stages of Disease Progression

inferred← citeshttps://doi.org/10.3389/fonc.2021.765329openalex-snapshot

Alterations of Ion Homeostasis in Cancer Metastasis: Implications for Treatment

inferred← citeshttps://doi.org/10.3389/pore.2022.1610608openalex-snapshot

Gene Expression Patterns of Osteopontin Isoforms and Integrins in Malignant Melanoma

inferred← citeshttps://doi.org/10.3390/biom11060813openalex-snapshot

Structural Constraint of Osteopontin Facilitates Efficient Binding to CD44

inferred← citeshttps://doi.org/10.3390/biomedicines12010031openalex-snapshot

Preliminary Study of the Relationship between Osteopontin and Relapsed Hodgkin’s Lymphoma

inferred← citeshttps://doi.org/10.3390/cancers12113379openalex-snapshot

Osteopontin: A Key Regulator of Tumor Progression and Immunomodulation

inferred← citeshttps://doi.org/10.3390/cancers13051006openalex-snapshot

Osteopontin Blockade Immunotherapy Increases Cytotoxic T Lymphocyte Lytic Activity and Suppresses Colon Tumor Progression

inferred← citeshttps://doi.org/10.3390/cells10071820openalex-snapshot

Distinctive Prognostic Value and Cellular Functions of Osteopontin Splice Variants in Human Gastric Cancer

inferred← citeshttps://doi.org/10.3390/cells8080815openalex-snapshot

Osteopontin as a Link between Inflammation and Cancer: The Thorax in the Spotlight

inferred← citeshttps://doi.org/10.3390/ijms19092557openalex-snapshot

The Phylogeny of Osteopontin—Analysis of the Protein Sequence

inferred← citeshttps://doi.org/10.3390/ijms19102990openalex-snapshot

OPNa Overexpression Is Associated with Matrix Calcification in Thyroid Cancer Cell Lines

inferred← citeshttps://doi.org/10.3390/ijms232315328openalex-snapshot

Osteopontin Splicing Isoforms Contribute to Endometriotic Proliferation, Migration, and Epithelial-Mesenchymal Transition in Endometrial Epithelial Cells

inferred← citeshttps://doi.org/10.3390/vaccines8040748openalex-snapshot

The Roles of Osteopontin in the Pathogenesis of West Nile Encephalitis

inferred← citeshttps://doi.org/10.3748/wjg.v18.i26.3389openalex-snapshot

Osteopontin increases hepatocellular carcinoma cell growth in a CD44 dependant manner

inferred← citeshttps://doi.org/10.3748/wjg.v20.i36.13088openalex-snapshot

Osteopontin is an important mediator of alcoholic liver diseaseviahepatic stellate cell activation

inferred← citeshttps://doi.org/10.3892/ijmm.2017.2964openalex-snapshot

Human osteopontin: Potential clinical applications in cancer (Review)

inferred← citeshttps://doi.org/10.3892/ijo.2014.2393openalex-snapshot

Osteopontin promotes the progression of gastric cancer through the NF-κB pathway regulated by the MAPK and PI3K

inferred← citeshttps://doi.org/10.3892/ijo.32.6.1285openalex-snapshot

DLC1 suppresses distant dissemination of human hepatocellular carcinoma cells in nude mice through reduction of RhoA GTPase activity, actin cytoskeletal disruption and down-regulation of genes involved in metastasis

inferred← citeshttps://doi.org/10.3892/ijo_00000458openalex-snapshot

Osteopontin splice variants differentially modulate the migratory activity of hepatocellular carcinoma cell lines

inferred← citeshttps://doi.org/10.3892/ijo_32_6_1285openalex-snapshot

inferred← citeshttps://doi.org/10.3892/mmr.2011.679openalex-snapshot

Down-regulation of osteopontin expression by RNA interference affects cell proliferation and chemotherapy sensitivity of breast cancer MDA-MB-231 cells

inferred← citeshttps://doi.org/10.3892/ol.2015.2939openalex-snapshot

Osteopontin-c mediates the upregulation of androgen responsive genes in LNCaP cells through PI3K/Akt and androgen receptor signaling

inferred← citeshttps://doi.org/10.3892/ol.2019.9896openalex-snapshot

Correlation of OPN gene expression with proliferation and apoptosis of ovarian cancer cells and prognosis of patients

inferred← citeshttps://doi.org/10.3892/or.2013.2632openalex-snapshot

An osteopontin promoter polymorphism is associated with aggressiveness in breast cancer

inferred← citeshttps://doi.org/10.3892/or.2018.6768openalex-snapshot

Anti‑osteopontin autoantibodies in various types of cancer

inferred← citeshttps://doi.org/10.4161/cbt.10.1.12452openalex-snapshot

Matricellular proteins osteopontin and osteonectin/SPARC in pancreatic carcinoma

inferred← citeshttps://doi.org/10.4161/isl.1.1.8629openalex-snapshot

Expression and regulation of osteopontin in type 1 diabetes

inferred← citeshttps://doi.org/10.53846/goediss-7595openalex-snapshot

Information theoretical approaches for the identification of potentially cooperating transcription factors

inferred← citeshttps://doi.org/10.5772/21115openalex-snapshot

Therapeutic Targeting of Osteopontin in Breast Cancer Cells

inferred← citeshttps://doi.org/10.6083/m4cf9n3bopenalex-snapshot

Development of novel therapeutics for stroke : preclinical investigations of osteopontin and 3-iodothyronamine.

inferred← citeshttps://doi.org/10.6084/m9.figshare.21251666openalex-snapshot

Additional file 1 of Breast cancer risk in papilloma patients: Osteopontin splice variants indicate prognosis

inferred← citeshttps://doi.org/10.6084/m9.figshare.22688733openalex-snapshot

Additional file 1 of Meta-analysis of Osteopontin splice variants in cancer

inferred← citeshttps://doi.org/10.7150/ijbs.5280openalex-snapshot

Osteopontin Splice Variants Differentially Exert Clinicopathological Features and Biological Functions in Gastric Cancer

inferred← citeshttps://doi.org/10.7150/jca.8925openalex-snapshot

Far Beyond the Usual Biomarkers in Breast Cancer: A Review

inferred← citeshttps://doi.org/10.7150/jca.91798openalex-snapshot

Programmed cell death-index (PCDi) as a prognostic biomarker and predictor of drug sensitivity in cervical cancer: a machine learning-based analysis of mRNA signatures

inferred← citeshttps://doi.org/10.7282/t30c4w05openalex-snapshot

Models for investigating functional roles of osteopontin

inferred← citeshttps://doi.org/10.7282/t3gf0txzopenalex-snapshot

Osteopontin and cell adhesion: role of post-translational modifications and the C-terminal region

inferred← citeshttps://doi.org/10.7314/apjcp.2013.14.12.7315openalex-snapshot

Overexpressed Ostepontin-c as a Potential Biomarker for Esophageal Squamous Cell Carcinoma

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