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Fungal naphtho-γ-pyrones: Potent antibiotics for drug-resistant microbial pathogens

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/1097-0134(20010501)43:2<217::aid-prot1032>3.0.co;2-gopenalex-snapshot
Ligand-protein inverse docking and its potential use in the computer search of protein targets of a small molecule
inferredcites →https://doi.org/10.1002/cbdv.201300042openalex-snapshot
Naphtho‐γ‐pyrones from Endophyte Aspergillus niger Occurring in the Liverwort Heteroscyphus tener ( Steph .) Schiffn .
inferredcites →https://doi.org/10.1002/cmdc.201300209openalex-snapshot
Recent Advances in Inhibitors of Bacterial Fatty Acid Synthesis Type II (FASII) System Enzymes as Potential Antibacterial Agents
inferredcites →https://doi.org/10.1002/jcc.540150503openalex-snapshot
ICM—A new method for protein modeling and design: Applications to docking and structure prediction from the distorted native conformation
inferredcites →https://doi.org/10.1002/prot.10630openalex-snapshot
The extended left‐handed helix: A simple nucleic acid‐binding motif
inferredcites →https://doi.org/10.1006/jmbi.2000.4457openalex-snapshot
Refined structures of β-ketoacyl-acyl carrier protein synthase III
inferredcites →https://doi.org/10.1007/s00253-014-6295-1openalex-snapshot
Fungal naphtho-γ-pyrones—secondary metabolites of industrial interest
inferredcites →https://doi.org/10.1016/j.bbrc.2007.08.144openalex-snapshot
Cephalochromin, a FabI-directed antibacterial of microbial origin
inferredcites →https://doi.org/10.1016/j.femsle.2004.10.005openalex-snapshot
Endophytic naphthopyrone metabolites are co-inhibitors of xanthine oxidase, SW1116 cell and some microbial growths
inferredcites →https://doi.org/10.1016/j.jmb.2010.12.003openalex-snapshot
Crystal Structures of Enoyl-ACP Reductases I (FabI) and III (FabL) from B. subtilis
inferredcites →https://doi.org/10.1016/j.jmb.2012.07.012openalex-snapshot
Crystal Structures of Penicillin-Binding Protein 3 (PBP3) from Methicillin-Resistant Staphylococcus aureus in the Apo and Cefotaxime‐Bound Forms
inferredcites →https://doi.org/10.1016/j.jmgm.2011.01.002openalex-snapshot
An inverse docking approach for identifying new potential anti-cancer targets
inferredcites →https://doi.org/10.1016/j.mimet.2004.04.017openalex-snapshot
Development of a robust microtiter plate-based assay method for assessment of bioactivity
inferredcites →https://doi.org/10.1016/j.molstruc.2014.03.009openalex-snapshot
MicroScale Thermophoresis: Interaction analysis and beyond
inferredcites →https://doi.org/10.1016/j.phytochem.2006.09.038openalex-snapshot
Asperpyrone D and other metabolites of the plant-associated fungal strain Aspergillus tubingensis
inferredcites →https://doi.org/10.1016/s0040-4020(01)88792-5openalex-snapshot
New naphthopyrones from aspergillus fonsecaeus
inferredcites →https://doi.org/10.1021/jm0204035openalex-snapshot
Indole Naphthyridinones as Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK
inferredcites →https://doi.org/10.1021/jm0600545openalex-snapshot
Inhibition ofPlasmodiumfalciparumFatty Acid Biosynthesis: Evaluation of FabG, FabZ, and FabI as Drug Targets for Flavonoids
inferredcites →https://doi.org/10.1021/jm061257wopenalex-snapshot
Discovery of a Rhodanine Class of Compounds as Inhibitors of Plasmodium falciparum Enoyl-Acyl Carrier Protein Reductase
inferredcites →https://doi.org/10.1021/ml200312sopenalex-snapshot
Fungal bis-Naphthopyrones as Inhibitors of Botulinum Neurotoxin Serotype A
inferredcites →https://doi.org/10.1021/np020174popenalex-snapshot
New Dimeric Naphthopyrones from Aspergillus niger
inferredcites →https://doi.org/10.1021/np020289topenalex-snapshot
Fatty Acid Synthase Inhibitors from Plants: Isolation, Structure Elucidation, and SAR Studies
inferredcites →https://doi.org/10.1021/np5000796openalex-snapshot
New Horizons for Old Drugs and Drug Leads
inferredcites →https://doi.org/10.1038/510477aopenalex-snapshot
To the rescue of old drugs
inferredcites →https://doi.org/10.1038/ja.2007.24openalex-snapshot
Nigerasperones A~C, New Monomeric and Dimeric Naphtho-γ-pyrones from a Marine Alga-derived Endophytic Fungus Aspergillus niger EN-13
inferredcites →https://doi.org/10.1038/ja.2008.76openalex-snapshot
Selective Inhibition of Acyl-CoA:cholesterol Acyltransferase 2 Isozyme by Flavasperone and Sterigmatocystin from Aspergillus Species
inferredcites →https://doi.org/10.1038/nature04784openalex-snapshot
Platensimycin is a selective FabF inhibitor with potent antibiotic properties
inferredcites →https://doi.org/10.1038/nature12810openalex-snapshot
Trapping the dynamic acyl carrier protein in fatty acid biosynthesis
inferredcites →https://doi.org/10.1038/nature13445openalex-snapshot
Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance
inferredcites →https://doi.org/10.1056/nejmoa053783openalex-snapshot
Daptomycin versus Standard Therapy for Bacteremia and Endocarditis Caused by Staphylococcus aureus
inferredcites →https://doi.org/10.1056/nejmoa0910812openalex-snapshot
Fidaxomicin versus Vancomycin for Clostridium difficile Infection
inferredcites →https://doi.org/10.1073/pnas.1205735109openalex-snapshot
Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors
inferredcites →https://doi.org/10.1073/pnas.84.19.6611openalex-snapshot
Monte Carlo-minimization approach to the multiple-minima problem in protein folding.
inferredcites →https://doi.org/10.1074/jbc.270.22.12961openalex-snapshot
The Escherichia coli Malonyl-CoA:Acyl Carrier Protein Transacylase at 1.5-Å Resolution.
inferredcites →https://doi.org/10.1074/jbc.m114.608497openalex-snapshot
Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule
inferredcites →https://doi.org/10.1074/jbc.m805783200openalex-snapshot
Crystal Structure of Biotin Carboxylase in Complex with Substrates and Implications for Its Catalytic Mechanism
inferredcites →https://doi.org/10.1086/591861openalex-snapshot
Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections: Annual Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006–2007
inferredcites →https://doi.org/10.1086/668770openalex-snapshot
Antimicrobial-Resistant Pathogens Associated with Healthcare-Associated Infections Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009–2010
inferredcites →https://doi.org/10.1093/jac/dkr154openalex-snapshot
Identification of antimicrobial activity among FDA-approved drugs for combating Mycobacterium abscessus and Mycobacterium chelonae
inferredcites →https://doi.org/10.1093/jac/dkr578openalex-snapshot
Mycobacterium abscessus: a new antibiotic nightmare
inferredcites →https://doi.org/10.1093/jb/mvh010openalex-snapshot
Inhibitory Effects of Flavonoids on Animal Fatty Acid Synthase
inferredcites →https://doi.org/10.1107/s0907444907049852openalex-snapshot
Structure-assisted discovery of an aminothiazole derivative as a lead molecule for inhibition of bacterial fatty-acid synthesis
inferredcites →https://doi.org/10.1110/ps.051373005openalex-snapshot
The crystal structure of PfFabZ, the unique β‐hydroxyacyl‐ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum
inferredcites →https://doi.org/10.1110/ps.31002openalex-snapshot
Composites of local structure propensities: Evidence for local encoding of long-range structure
inferredcites →https://doi.org/10.1110/ps.8.11.2529openalex-snapshot
Molecular basis for triclosan activity involves a flipping loop in the active site
inferredcites →https://doi.org/10.1128/aac.01456-07openalex-snapshot
Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae
inferredcites →https://doi.org/10.1146/annurev.micro.55.1.305openalex-snapshot
Bacterial Fatty Acid Biosynthesis: Targets for Antibacterial Drug Discovery
inferredcites →https://doi.org/10.1186/2191-2858-2-6openalex-snapshot
Seven naphtho-γ-pyrones from the marine-derived fungus Alternaria alternata: structure elucidation and biological properties
inferredcites →https://doi.org/10.1248/cpb.35.4049openalex-snapshot
Absolute configurations of chaetochromin A and related bis(naphtho-.GAMMA.-pyrone) mold metabolites.
inferredcites →https://doi.org/10.2174/1389557510909030273openalex-snapshot
Linear Naphtho-γ-Pyrones: A Naturally Occurring Scaffold of Biological Importance
inferredcites →https://doi.org/10.3390/molecules19067169openalex-snapshot
Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities
inferredcites →https://doi.org/10.3390/ph4050681openalex-snapshot
Expanding the Antimalarial Drug Arsenal—Now, But How?

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112613zenodo-depositor-declared
Hypoxylonoids A−G: Isopimarane diterpene glycosides from Xylaria hypoxylon
inferred← citeshttps://doi.org/10.1002/adsc.201800874openalex-snapshot
Transition‐Metal‐Free Regioselective Construction of Diverse 3‐Carbonyl Functionalized 4‐Pyrones via Thermal Wolff‐Rearrangement of Diazodicarbonyls
inferred← citeshttps://doi.org/10.1002/cbdv.202503087openalex-snapshot
Naphtho‐γ‐pyrones From Aspergillus foetidus , an Endophytic Fungus Isolated From Gardenia jasminoides J. Ellis
inferred← citeshttps://doi.org/10.1002/jssc.201800733openalex-snapshot
Separation of five naphtho‐γ‐pyrones from Pleurotus ostreatus by high‐speed countercurrent chromatography
inferred← citeshttps://doi.org/10.1007/978-3-030-84126-3_14openalex-snapshot
Chemical Diversity in Fungi: Strategies to Mitigate Antimicrobial Resistance
inferred← citeshttps://doi.org/10.1007/978-3-319-69075-9_3openalex-snapshot
Anti-infective Compounds from Marine Organisms
inferred← citeshttps://doi.org/10.1007/978-94-007-6167-4_603-1openalex-snapshot
Fungi Ethics
inferred← citeshttps://doi.org/10.1007/978-94-024-1179-9_603openalex-snapshot
Fungi Ethics
inferred← citeshttps://doi.org/10.1007/s00253-018-9354-1openalex-snapshot
Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei
inferred← citeshttps://doi.org/10.1007/s11418-023-01696-9openalex-snapshot
Inhibition of Aβ aggregation by naphtho-γ-pyrone derivatives from a marine-derived fungus, Aspergillus sp. MPUC239
inferred← citeshttps://doi.org/10.1007/s11756-021-00697-xopenalex-snapshot
Antibiotic resistance crisis: challenges and imperatives
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2017.07.015openalex-snapshot
Fungi isolated from Madagascar shrimps - investigation of the Aspergillus niger metabolism by combined LC-MS and NMR metabolomics studies
inferred← citeshttps://doi.org/10.1016/j.micpath.2020.104066openalex-snapshot
Polyketides from marine-derived Aspergillus welwitschiae inhibit Staphylococcus aureus virulence factors and potentiate vancomycin antibacterial activity in vivo
inferred← citeshttps://doi.org/10.1016/j.molstruc.2021.131077openalex-snapshot
Synthesis, characterization, molecular structure, and computational studies on 4(1H)-pyran-4-one and its derivatives
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.0c01262openalex-snapshot
Naphtho-γ-pyrone Dimers from an Endozoic Aspergillus niger and the Effects of Coisolated Monomers in Combination with Cisplatin on a Cisplatin-Resistant A549 Cell Line
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.7b00077openalex-snapshot
Bioassay-Guided Isolation of Antibacterial Metabolites from Emericella sp. TJ29
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.9b00560openalex-snapshot
Anti-inflammatory Metabolites from Chaetomium nigricolor
inferred← citeshttps://doi.org/10.1021/acs.joc.0c02324openalex-snapshot
Synthesis of the Fungal Metabolite YWA1 and Related Constructs as Tools to Study MelLec-Mediated Immune Response to Aspergillus Infections
inferred← citeshttps://doi.org/10.1021/acs.joc.7b00056openalex-snapshot
Spiroaspertrione A, a Bridged Spirocyclic Meroterpenoid, as a Potent Potentiator of Oxacillin against Methicillin-Resistant Staphylococcus aureus from Aspergillus sp. TJ23
inferred← citeshttps://doi.org/10.1021/acschembio.4c00562openalex-snapshot
Antimicrobial Agent Trimethoprim Influences Chemical Interactions in Cystic Fibrosis Pathogens via the ham Gene Cluster
inferred← citeshttps://doi.org/10.1038/s41598-018-23817-1openalex-snapshot
Aspermerodione, a novel fungal metabolite with an unusual 2,6-dioxabicyclo[2.2.1]heptane skeleton, as an inhibitor of penicillin-binding protein 2a
inferred← citeshttps://doi.org/10.1039/c6qo00847jopenalex-snapshot
Asperspiropene A, a novel fungal metabolite as an inhibitor of cancer-associated mutant isocitrate dehydrogenase 1
inferred← citeshttps://doi.org/10.1039/c8qo01006dopenalex-snapshot
Regiospecific construction of diverse and polyfunctionalized γ-pyrone cores by indium( iii )-catalyzed annulation of diazodicarbonyls with active methylenes, 4-hydroxycoumarins, or 4-hydroxyquinolinone
inferred← citeshttps://doi.org/10.1080/14786419.2018.1481844openalex-snapshot
Asperpyrone F, a new dimeric naphtho-γ-pyrone from the edible fungus Pleurotus ostreatus
inferred← citeshttps://doi.org/10.1080/14786419.2018.1544982openalex-snapshot
Antimicrobial secondary metabolites of an endolichenic Aspergillus niger isolated from lichen thallus of Parmotrema ravum
inferred← citeshttps://doi.org/10.1080/14786419.2019.1610954openalex-snapshot
Naphto-Γ-pyrones from the marine-derived fungus Aspergillus foetidus
inferred← citeshttps://doi.org/10.1080/14786419.2020.1828407openalex-snapshot
One new piperazinedione isolated from a mangrove-derived fungus Aspergillus niger JX-5
inferred← citeshttps://doi.org/10.1080/14787210.2022.2045194openalex-snapshot
Bacteria and fungi as major bio-sources to fabricate silver nanoparticles with antibacterial activities
inferred← citeshttps://doi.org/10.1177/1934578x19860378openalex-snapshot
Penichrypyrone A: A New γ-Pyrone Derivative from the Sponge-Derived Fungus Penicillium chrysogenum LS18
inferred← citeshttps://doi.org/10.1186/s13568-023-01568-1openalex-snapshot
Antimicrobial, antiproliferative activities and molecular docking of metabolites from Alternaria alternata
inferred← citeshttps://doi.org/10.2174/1385272824666200217101400openalex-snapshot
Pyrone-derived Marine Natural Products: A Review on Isolation, Bio-activities and Synthesis
inferred← citeshttps://doi.org/10.29356/jmcs.v69i2.2213openalex-snapshot
Pyrone Biomonitored Synthesis
inferred← citeshttps://doi.org/10.3390/antibiotics9100658openalex-snapshot
Synergistic Therapies as a Promising Option for the Treatment of Antibiotic-Resistant Helicobacter pylori
inferred← citeshttps://doi.org/10.3390/biom10010029openalex-snapshot
Naphtho-Gamma-Pyrones Produced by Aspergillus tubingensis G131: New Source of Natural Nontoxic Antioxidants
inferred← citeshttps://doi.org/10.3390/biotech14040094openalex-snapshot
A Comprehensive Review of Plant and Microbial Natural Compounds as Sources of Potential Helicobacter pylori-Inhibiting Agents
inferred← citeshttps://doi.org/10.3390/md24040125openalex-snapshot
Anti-Neuroinflammatory Naphtho-γ-Pyrones from a Deep-Sea-Derived Fungus Aspergillus niger 3A00562
inferred← citeshttps://doi.org/10.3390/molecules25215058openalex-snapshot
Teratopyrones A–C, Dimeric Naphtho-γ-Pyrones and Other Metabolites from Teratosphaeria sp. AK1128, a Fungal Endophyte of Equisetum arvense
inferred← citeshttps://doi.org/10.3390/molecules27082514openalex-snapshot
Naphtho-Gamma-Pyrones (NγPs) with Obvious Cholesterol Absorption Inhibitory Activity from the Marine-Derived Fungus Aspergillus niger S-48
inferred← citeshttps://doi.org/10.3390/ph17121678openalex-snapshot
Effect of Mn(II) and Co(II) on Anti-Candida Metabolite Production by Aspergillus sp. an Endophyte Isolated from Dizygostemon riparius (Plantaginaceae)
inferred← citeshttps://doi.org/10.53730/ijhs.v5ns1.15182openalex-snapshot
Understanding antibiotic resistance: Challenges and solutions
inferred← citeshttps://doi.org/10.6084/m9.figshare.26602789openalex-snapshot
Additional file 1 of Antimicrobial, antiproliferative activities and molecular docking of metabolites from Alternaria alternata
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