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Activation of liver X receptor inhibits the development of pulmonary carcinomas induced by 3-methylcholanthrene and butylated hydroxytoluene in BALB/c mice

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ijc.24743openalex-snapshot

Epistatic interactions govern chemically‐induced lung tumor susceptibility and Kras mutation site in murine C57BL/6J‐ChrA/J chromosome substitution strains

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Neutrophils are required for 3‐methylcholanthrene‐initiated, butylated hydroxytoluene‐promoted lung carcinogenesis

inferredcites →https://doi.org/10.1016/0304-3835(94)03715-uopenalex-snapshot

Mutations of the Ki-ras protooncogene in 3-methylcholanthrene and urethan-induced and butylated hydroxytoluene-promoted lung tumors of strain A/J and SWR mice

inferredcites →https://doi.org/10.1016/j.cell.2004.09.032openalex-snapshot

LXR-Dependent Gene Expression Is Important for Macrophage Survival and the Innate Immune Response

inferredcites →https://doi.org/10.1016/j.cell.2014.01.038openalex-snapshot

Broad-Spectrum Therapeutic Suppression of Metastatic Melanoma through Nuclear Hormone Receptor Activation

inferredcites →https://doi.org/10.1016/j.intimp.2011.12.016openalex-snapshot

IFN-γ producing T cells contribute to the increase of myeloid derived suppressor cells in tumor-bearing mice after cyclophosphamide treatment

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Involvement of EZH2, SUV39H1, G9a and associated molecules in pathogenesis of urethane induced mouse lung tumors: Potential targets for cancer control

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Morphine analgesia suppresses tumor growth and metastasis in a mouse model of cancer pain produced by orthotopic tumor inoculation

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IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity

inferredcites →https://doi.org/10.1038/cdd.2014.117openalex-snapshot

Liver X receptor β activation induces pyroptosis of human and murine colon cancer cells

inferredcites →https://doi.org/10.1038/nm.2074openalex-snapshot

Tumor-mediated liver X receptor-α activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

inferredcites →https://doi.org/10.1042/bj20131442openalex-snapshot

Identification of interferon-γ as a new molecular target of liver X receptor

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Epithelial NF-κB activation promotes urethane-induced lung carcinogenesis

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Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice

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Peroxisome Proliferator-activated Receptor γ Activation by Ligands and Dephosphorylation Induces Proprotein Convertase Subtilisin Kexin Type 9 and Low Density Lipoprotein Receptor Expression

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Stimulation of Lipogenesis by Pharmacological Activation of the Liver X Receptor Leads to Production of Large, Triglyceride-rich Very Low Density Lipoprotein Particles

inferredcites →https://doi.org/10.1084/jem.20112738openalex-snapshot

Cancer immunoediting by the innate immune system in the absence of adaptive immunity

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Enhancing In Vivo Tumorigenicity of B16 Melanoma by Overexpressing Interferon Regulatory Factor-2: Resistance to Endogenous IFN-gamma

inferredcites →https://doi.org/10.1089/jir.1998.18.17openalex-snapshot

Orally Administered IFN-α Acts Alone and in Synergistic Combination with Intraperitoneally Administered IFN-γ to Exert an Antitumor Effect Against B16 Melanoma in Mice

inferredcites →https://doi.org/10.1093/carcin/bgp029openalex-snapshot

The oxysterol receptor LXR inhibits proliferation of human breast cancer cells

inferredcites →https://doi.org/10.1158/1535-7163.mct-13-0997openalex-snapshot

Activation of Liver X Receptors Inhibits Hedgehog Signaling, Clonogenic Growth, and Self-Renewal in Multiple Myeloma

inferredcites →https://doi.org/10.1161/atvbaha.112.250621openalex-snapshot

Liver X Receptor Activation Reduces Angiogenesis by Impairing Lipid Raft Localization and Signaling of Vascular Endothelial Growth Factor Receptor-2

inferredcites →https://doi.org/10.1161/atvbaha.114.305116openalex-snapshot

Inhibition of ERK1/2 and Activation of LXR Synergistically Reduce Atherosclerotic Lesions in ApoE-Deficient Mice

inferredcites →https://doi.org/10.1186/1743-8977-11-3openalex-snapshot

Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes

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IFN-γ production by lung NK cells is critical for the natural resistance to pulmonary metastasis of B16 melanoma in mice

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Interferon-γ: an overview of signals, mechanisms and functions

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Combined IFN-γ–Endostatin Gene Therapy and Radiotherapy Attenuates Primary Breast Tumor Growth and Lung Metastases via Enhanced CTL and NK Cell Activation and Attenuated Tumor Angiogenesis in a Murine Model

inferredcites →https://doi.org/10.3892/ijo.7.3.501openalex-snapshot

IFN-GAMMA AND B7 AS COSTIMULATORS OF ANTITUMOR IMMUNE-RESPONSES

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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A Novel Exhaled Gas Detection Model for Diagnosis and Prognosis Prediction of Colorectal Cancer

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Real‐Time Evolutionary Landscape of the Bronchial Epithelium and Corresponding Dynamic Immune Cell Alterations in Lung Squamous Cell Carcinogenesis

inferred← citeshttps://doi.org/10.1007/s10456-018-9604-yopenalex-snapshot

Time-dependent LXR/RXR pathway modulation characterizes capillary remodeling in inflammatory corneal neovascularization

inferred← citeshttps://doi.org/10.1007/s10565-024-09846-9openalex-snapshot

m6A modification mediates SLC3A2/SLC7A5 translation in 3-methylcholanthrene-induced uroepithelial transformation

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CD36 inhibition reduces non-small-cell lung cancer development through AKT-mTOR pathway

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Activation of CTU2 expression by LXR promotes the development of hepatocellular carcinoma

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Evaluation of selected antidiabetics in cardiovascular complications associated with cancer cachexia

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A holistic computational exploration of AZD7762 as a potent selective modulator of LXRα, LXRβ and FXR: An underexplored pathway in cancer therapeutics

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IFI44L as a novel epigenetic silencing tumor suppressor promotes apoptosis through JAK/STAT1 pathway during lung carcinogenesis

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Murine models of lung adenocarcinoma: Valuable tools for preclinical investigation

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Determination of volatile organic compounds in SW620 colorectal cancer cells and tumor-bearing mice

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DNA methylation and hydroxymethylation associated with gene expression regulatory network during 3-methylcholanthrene induced lung cell malignant transformation

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Profile of mRNA expression in the myometrium after intrauterine Escherichia coli injections in pigs

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Dendrogenin A drives LXR to trigger lethal autophagy in cancers

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Inhibition Role of Atherogenic Diet on Ethyl Carbamate Induced Lung Tumorigenesis in C57BL/6J Mice

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Metabolic, toxicological, chemical, and commercial perspectives on esterification of dietary polyphenols: a review

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Lipid metabolic reprograming: the unsung hero in breast cancer progression and tumor microenvironment

inferred← citeshttps://doi.org/10.1194/jlr.m084558openalex-snapshot

Activation of liver X receptor plays a central role in antiviral actions of 25-hydroxycholesterol

inferred← citeshttps://doi.org/10.21203/rs.3.rs-3710751/v1openalex-snapshot

A Novel Exhaled Gas Detection Model for Diagnosis and Prognosis Prediction of Colorectal Cancer

inferred← citeshttps://doi.org/10.3389/fcell.2024.1386102openalex-snapshot

Liver X Receptors (LXRs) in cancer-an Eagle’s view on molecular insights and therapeutic opportunities

inferred← citeshttps://doi.org/10.3389/fmed.2021.799051openalex-snapshot

Pre-transplant Transcriptional Signature in Peripheral Blood Mononuclear Cells of Acute Renal Allograft Rejection

inferred← citeshttps://doi.org/10.33899/ijvs.2020.126435.1322openalex-snapshot

Toxic effects of butylated hydroxytoluene in rats

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ER-Negative Breast Cancer Is Highly Responsive to Cholesterol Metabolite Signalling

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Targeting Liver X Receptors in Cancer Drug Discovery

inferred← citeshttps://doi.org/10.3892/ol.2017.7259openalex-snapshot

Liver X receptors as potential targets for cancer therapeutics (Review)

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Encapsulation of LXR ligand by D-Nap-GFFY hydrogel enhances anti-tumorigenic actions of LXR and removes LXR-induced lipogenesis

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