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Vancomycin susceptibility in methicillin-resistant Staphylococcus aureus is mediated by YycHI activation of the WalRK essential two-component regulatory system
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1006/mpat.1996.0099openalex-snapshot
PhoP/Q regulated genes inSalmonella typhi: identification of melittin sensitive mutants
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Site-directed mutagenesis by overlap extension using the polymerase chain reaction
inferredcites →https://doi.org/10.1016/j.dnarep.2013.02.002openalex-snapshot
Evidence that YycJ is a novel 5′–3′ double-stranded DNA exonuclease acting in Bacillus anthracis mismatch repair
inferredcites →https://doi.org/10.1016/j.ijmm.2007.02.002openalex-snapshot
Role of insertion elements and yycFG in the development of decreased susceptibility to vancomycin in Staphylococcus aureus
inferredcites →https://doi.org/10.1016/j.mib.2005.02.011openalex-snapshot
PII signal transduction proteins: sensors of α-ketoglutarate that regulate nitrogen metabolism
inferredcites →https://doi.org/10.1016/j.plasmid.2005.05.005openalex-snapshot
Allelic replacement in Staphylococcus aureus with inducible counter-selection
inferredcites →https://doi.org/10.1038/nmeth.1226openalex-snapshot
Mapping and quantifying mammalian transcriptomes by RNA-Seq
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Antimicrobial peptides from platelets
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Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing
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An essential sensor histidine kinase controlled by transmembrane helix interactions with its auxiliary proteins
inferredcites →https://doi.org/10.1073/pnas.95.10.5752openalex-snapshot
A bacterial two-hybrid system based on a reconstituted signal transduction pathway
inferredcites →https://doi.org/10.1086/345476openalex-snapshot
Comparison of Mortality Associated with Methicillin‐Resistant and Methicillin‐Susceptible Staphylococcus aureus Bacteremia: A Meta‐analysis
inferredcites →https://doi.org/10.1086/381093openalex-snapshot
Clinical Features Associated with Bacteremia Due to Heterogeneous Vancomycin‐IntermediateStaphylococcus aureus
inferredcites →https://doi.org/10.1086/381202openalex-snapshot
Treatment Outcomes for Serious Infections Caused by Methicillin‐Resistant Staphylococcus aureus with Reduced Vancomycin Susceptibility
inferredcites →https://doi.org/10.1086/524667openalex-snapshot
Influence of Vancomycin Minimum Inhibitory Concentration on the Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia
inferredcites →https://doi.org/10.1093/cid/cir473openalex-snapshot
The Interface Between Antibiotic Resistance and Virulence in Staphylococcus aureus and Its Impact Upon Clinical Outcomes
inferredcites →https://doi.org/10.1093/cid/cir935openalex-snapshot
The Clinical Significance of Vancomycin Minimum Inhibitory Concentration in Staphylococcus aureus Infections: A Systematic Review and Meta-analysis
inferredcites →https://doi.org/10.1093/infdis/jis252openalex-snapshot
Serine/Threonine Phosphatase Stp1 Contributes to Reduced Susceptibility to Vancomycin and Virulence in Staphylococcus aureus
inferredcites →https://doi.org/10.1093/jac/47.4.399openalex-snapshot
A modified population analysis profile (PAP) method to detect hetero-resistance to vancomycin in Staphylococcus aureus in a UK hospital
inferredcites →https://doi.org/10.1093/jac/dkq050openalex-snapshot
Predictors of persistent methicillin-resistant Staphylococcus aureus bacteraemia in patients treated with vancomycin
inferredcites →https://doi.org/10.1101/gr.124321.111openalex-snapshot
Differential expression in RNA-seq: A matter of depth
inferredcites →https://doi.org/10.1111/j.1365-2958.2008.06308.xopenalex-snapshot
A sensor histidine kinase co‐ordinates cell wall architecture with cell division in Bacillus subtilis
inferredcites →https://doi.org/10.1111/j.1365-2958.2008.06483.xopenalex-snapshot
A matter of life and death: cell wall homeostasis and the WalKR (YycGF) essential signal transduction pathway
inferredcites →https://doi.org/10.1111/j.1365-2958.2012.08198.xopenalex-snapshot
The auxiliary protein complex SaePQ activates the phosphatase activity of sensor kinase SaeS in the SaeRS two‐component system of S taphylococcus aureus
inferredcites →https://doi.org/10.1128/aac.00279-13openalex-snapshot
Decreased Vancomycin Susceptibility in Staphylococcus aureus Caused by IS 256 Tempering of WalKR Expression
inferredcites →https://doi.org/10.1128/aac.00380-13openalex-snapshot
Clinical Outcomes in Patients with Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Bloodstream Infection
inferredcites →https://doi.org/10.1128/aac.00437-10openalex-snapshot
An RpoB Mutation Confers Dual Heteroresistance to Daptomycin and Vancomycin in Staphylococcus aureus
inferredcites →https://doi.org/10.1128/aac.01173-08openalex-snapshot
Contribution of vraSR and graSR Point Mutations to Vancomycin Resistance in Vancomycin-Intermediate Staphylococcus aureus
inferredcites →https://doi.org/10.1128/aac.01563-10openalex-snapshot
walK and clpP Mutations Confer Reduced Vancomycin Susceptibility in Staphylococcus aureus
inferredcites →https://doi.org/10.1128/aac.01613-07openalex-snapshot
Genomic Analysis Reveals a Point Mutation in the Two-Component Sensor Gene graS That Leads to Intermediate Vancomycin Resistance in Clinical Staphylococcus aureus
inferredcites →https://doi.org/10.1128/aac.05770-11openalex-snapshot
A Mutation in the PP2C Phosphatase Gene in a Staphylococcus aureus USA300 Clinical Isolate with Reduced Susceptibility to Vancomycin and Daptomycin
inferredcites →https://doi.org/10.1128/cmr.00042-09openalex-snapshot
Reduced Vancomycin Susceptibility in Staphylococcus aureus , Including Vancomycin-Intermediate and Heterogeneous Vancomycin-Intermediate Strains: Resistance Mechanisms, Laboratory Detection, and Clinical Implications
inferredcites →https://doi.org/10.1128/iai.00195-12openalex-snapshot
The WalKR System Controls Major Staphylococcal Virulence Genes and Is Involved in Triggering the Host Inflammatory Response
inferredcites →https://doi.org/10.1128/iai.70.7.3389-3395.2002openalex-snapshot
Overproduction of Type 8 Capsular Polysaccharide AugmentsStaphylococcus aureusVirulence
inferredcites →https://doi.org/10.1128/jb.00645-07openalex-snapshot
New Insights into the WalK/WalR (YycG/YycF) Essential Signal Transduction Pathway Reveal a Major Role in Controlling Cell Wall Metabolism and Biofilm Formation inStaphylococcus aureus
inferredcites →https://doi.org/10.1128/jb.01936-06openalex-snapshot
YycH and YycI Interact To Regulate the Essential YycFG Two-Component System in Bacillus subtilis
inferredcites →https://doi.org/10.1128/jb.158.2.513-516.1984openalex-snapshot
Low-affinity penicillin-binding protein associated with beta-lactam resistance in Staphylococcus aureus
inferredcites →https://doi.org/10.1128/jb.186.4.1175-1181.2004openalex-snapshot
Identification of Genes Controlled by the Essential YycG/YycF Two-Component System ofStaphylococcus aureus
inferredcites →https://doi.org/10.1128/jb.188.3.1120-1133.2006openalex-snapshot
Overexpression of Genes of the Cell Wall Stimulon in Clinical Isolates ofStaphylococcus aureusExhibiting Vancomycin-Intermediate-S. aureus-Type Resistance to Vancomycin
inferredcites →https://doi.org/10.1128/mbio.00277-11openalex-snapshot
Transforming the Untransformable: Application of Direct Transformation To Manipulate Genetically Staphylococcus aureus and Staphylococcus epidermidis
inferredcites →https://doi.org/10.1186/1471-2180-8-39openalex-snapshot
Different bacterial gene expression patterns and attenuated host immune responses are associated with the evolution of low-level vancomycin resistance during persistent methicillin-resistant Staphylococcus aureus bacteraemia
inferredcites →https://doi.org/10.1371/journal.pone.0017054openalex-snapshot
Peptidoglycan Crosslinking Relaxation Plays an Important Role in Staphylococcus aureus WalKR-Dependent Cell Viability
inferredcites →https://doi.org/10.1371/journal.pone.0030403openalex-snapshot
Purification and Activity Testing of the Full-Length YycFGHI Proteins of Staphylococcus aureus
inferredcites →https://doi.org/10.1371/journal.ppat.1002359openalex-snapshot
Evolution of Multidrug Resistance during Staphylococcus aureus Infection Involves Mutation of the Essential Two Component Regulator WalKR
inferredcites →https://doi.org/10.1371/journal.ppat.1002505openalex-snapshot
Genetic Pathway in Acquisition and Loss of Vancomycin Resistance in a Methicillin Resistant Staphylococcus aureus (MRSA) Strain of Clonal Type USA300
inferredcites →https://doi.org/10.1385/0-89603-310-4:209openalex-snapshot
Electrotransformation of Staphylococci
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Comprehensive Analysis of Antimicrobial Resistance, Biofilm Formation and Virulence Factors of Staphylococci Isolated from Bovine Mastitis
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Characterization of methicillin-resistant Staphylococcus aureus through genomics approach
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Nano-based intervention against methicillin-resistant Staphylococcus aureus
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New strategies for targeting and treatment of multi-drug resistant Staphylococcus aureus
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Comprehensive analysis of antimicrobial resistance, biofilm formation and virulence factors of staphylococci isolated from bovine mastitis
inferred← citeshttps://doi.org/10.1016/j.jbc.2022.102473openalex-snapshot
A defect in cell wall recycling confers antibiotic resistance and sensitivity in Staphylococcus aureus
inferred← citeshttps://doi.org/10.1016/j.jgar.2020.06.010openalex-snapshot
Relationship between virulence factors and antimicrobial resistance in Staphylococcus aureus from bovine mastitis
inferred← citeshttps://doi.org/10.1016/j.jiph.2026.103267openalex-snapshot
Prevalence and management of vancomycin non-susceptible Staphylococcus aureus: A narrative review
inferred← citeshttps://doi.org/10.1016/j.micpath.2021.105119openalex-snapshot
Five major two components systems of Staphylococcus aureus for adaptation in diverse hostile environment
inferred← citeshttps://doi.org/10.1016/j.sjbs.2023.103604openalex-snapshot
Antimicrobial resistance in methicillin-resistant staphylococcus aureus
inferred← citeshttps://doi.org/10.1038/s41467-019-10932-4openalex-snapshot
Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus
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A multi-hospital, clinician-initiated bacterial genomics programme to investigate treatment failure in severe Staphylococcus aureus infections
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Environmental conditions dictate differential evolution of vancomycin resistance in Staphylococcus aureus
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Synthesis and antibacterial profiling of novel pyrimidine-sulfonyl chlorides: a new class of antimicrobials targeting multidrug-resistant bacterial strains
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Revealing 29 sets of independently modulated genes in Staphylococcus aureus , their regulators, and role in key physiological response
inferred← citeshttps://doi.org/10.1080/09168451.2018.1444466openalex-snapshot
Essentiality and function of WalK/WalR two-component system: the past, present, and future of research*
inferred← citeshttps://doi.org/10.1080/17460913.2025.2574640openalex-snapshot
Synergistic drug strategy against mastitis-associated MRSA strains
inferred← citeshttps://doi.org/10.1093/infdis/jiz571openalex-snapshot
In-Host Evolution of Daptomycin Resistance and Heteroresistance in Methicillin-Resistant Staphylococcus aureus Strains From Three Endocarditis Patients
inferred← citeshttps://doi.org/10.1099/mic.0.001096openalex-snapshot
The MpsB protein contributes to both the toxicity and immune evasion capacity of Staphylococcus aureus
inferred← citeshttps://doi.org/10.1101/2023.02.27.530350openalex-snapshot
The two-component regulator WalKR provides an essential link between cell wall homeostasis with DNA replication in Staphylococcus aureus
inferred← citeshttps://doi.org/10.1101/2023.10.23.23297384openalex-snapshot
A multi-hospital, clinician-initiated bacterial genomics program to investigate treatment failure in severe Staphylococcus aureus infections
inferred← citeshttps://doi.org/10.1111/mmi.13751openalex-snapshot
Non‐canonical activation of histidine kinase KdpD by phosphotransferase protein PtsN through interaction with the transmitter domain
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Phenotypic and genetic stepwise changes in Staphylococcus aureus during in vitro adaptive laboratory evolution under the selective pressure of tigecycline
inferred← citeshttps://doi.org/10.1128/aac.00893-23openalex-snapshot
AgrA directly binds to the promoter of vraSR and downregulates its expression in Staphylococcus aureus
inferred← citeshttps://doi.org/10.1128/mbio.02262-23openalex-snapshot
The two-component system WalKR provides an essential link between cell wall homeostasis and DNA replication in Staphylococcus aureus
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Evolutionary trajectories of β-lactam resistance in Enterococcus faecalis strains
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Mutation in the Two-Component System Regulator YycH Leads to Daptomycin Tolerance in Methicillin-Resistant Staphylococcus aureus upon Evolution with a Population Bottleneck
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Cervimycin-Resistant Staphylococcus aureus Strains Display Vancomycin-Intermediate Resistant Phenotypes
inferred← citeshttps://doi.org/10.1186/s13018-018-1055-zopenalex-snapshot
Staphylococcus aureus biofilm organization modulated by YycFG two-component regulatory pathway
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Characterization of genetic changes associated with daptomycin nonsusceptibility in Staphylococcus aureus
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Comprehensive Analysis of Antimicrobial Resistance, Biofilm Formation and Virulence Factors of Staphylococci Isolated from Bovine Mastitis
inferred← citeshttps://doi.org/10.3389/fmicb.2016.02163openalex-snapshot
Novel Mutation Sites in the Development of Vancomycin- Intermediate Resistance in Staphylococcus aureus
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Identification of Genes Controlled by the Essential YycFG Two-Component System Reveals a Role for Biofilm Modulation in Staphylococcus epidermidis
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Evolution of Multi-Resistance to Vancomycin, Daptomycin, and Linezolid in Methicillin-Resistant Staphylococcus aureus Causing Persistent Bacteremia
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The Role of Staphylococcus aureus YycFG in Gene Regulation, Biofilm Organization and Drug Resistance
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Overcoming Methicillin-Resistance Staphylococcus aureus (MRSA) Using Antimicrobial Peptides-Silver Nanoparticles
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Comparative Genomics Identifies Novel Genetic Changes Associated with Oxacillin, Vancomycin and Daptomycin Susceptibility in ST100 Methicillin-Resistant Staphylococcus aureus
inferred← citeshttps://doi.org/10.3390/antibiotics12020402openalex-snapshot
Overview of Virulence and Antibiotic Resistance in Campylobacter spp. Livestock Isolates
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Adaptive Laboratory Evolution of Staphylococcus aureus Resistance to Vancomycin and Daptomycin: Mutation Patterns and Cross-Resistance
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Selective Bacteriocins: A Promising Treatment for Staphylococcus aureus Skin Infections Reveals Insights into Resistant Mutants, Vancomycin Resistance, and Cell Wall Alterations
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