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Zephycandidine A, the First Naturally Occurring Imidazo[1,2-f]phenanthridine Alkaloid from Zephyranthes candida, Exhibits Significant Anti-tumor and Anti-acetylcholinesterase Activities

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

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A new and rapid colorimetric determination of acetylcholinesterase activity

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A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

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N-methylhemeanthidine chloride, a novel Amaryllidaceae alkaloid, inhibits pancreatic cancer cell proliferation via down-regulating AKT activation

inferredcites →https://doi.org/10.1016/s0021-9673(01)00624-0openalex-snapshot

Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining

inferredcites →https://doi.org/10.1016/s0969-2126(99)80040-9openalex-snapshot

Structure of acetylcholinesterase complexed with E2020 (Aricept®): implications for the design of new anti-Alzheimer drugs

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Galanthamine, Plicamine, and Secoplicamine Alkaloids from Zephyranthes candida and Their Anti-acetylcholinesterase and Anti-inflammatory Activities

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Generating Conformer Ensembles Using a Multiobjective Genetic Algorithm

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Quantum Mechanical Continuum Solvation Models

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Specific Targeting of Acetylcholinesterase and Butyrylcholinesterase Recognition Sites. Rational Design of Novel, Selective, and Highly Potent Cholinesterase Inhibitors

inferredcites →https://doi.org/10.1021/jm300871xopenalex-snapshot

Structures of Human Acetylcholinesterase in Complex with Pharmacologically Important Ligands

inferredcites →https://doi.org/10.1021/jo800960wopenalex-snapshot

Structure Revision of Spiroleucettadine, a Sponge Alkaloid with a Bicyclic Core Meager in H-Atoms

inferredcites →https://doi.org/10.1021/ml400304wopenalex-snapshot

Structures of Human Acetylcholinesterase Bound to Dihydrotanshinone I and Territrem B Show Peripheral Site Flexibility

inferredcites →https://doi.org/10.1021/np3005425openalex-snapshot

Cytotoxic Alkaloids from the Whole Plants of Zephyranthes candida

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Antineoplastic Agents, 162. Zephyranthes candida

inferredcites →https://doi.org/10.1021/ol0611346openalex-snapshot

Predicting NMR Spectra by Computational Methods: Structure Revision of Hexacyclinol

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Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting shingosine kinase-1

inferredcites →https://doi.org/10.1039/b517117bopenalex-snapshot

Discovery of an imidazo-phenanthridine synthon produced in a ‘five-step one-pot reaction’ leading to a new family of heterocycles with novel physical properties

inferredcites →https://doi.org/10.1039/b718044fopenalex-snapshot

Amaryllidaceae and Sceletium alkaloids

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Amaryllidaceae and Sceletium alkaloids

inferredcites →https://doi.org/10.1073/pnas.1301814110openalex-snapshot

Free energy landscape for the binding process of Huperzine A to acetylcholinesterase

inferredcites →https://doi.org/10.1111/j.1365-2184.2012.00845.xopenalex-snapshot

Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis

inferredcites →https://doi.org/10.1136/jmg.2009.066944openalex-snapshot

Apoptosis and cancer: mutations within caspase genes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Monoterpene indole alkaloids with diverse skeletons from the stems of Rauvolfia vomitoria and their acetylcholinesterase inhibitory activities

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Highly oxygenated isoryanodane diterpenoids from the leaves of Cinnamomum cassia and their immunomodulatory activities

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Molecular Networking Accelerated Discovery of Biflavonoid Alkaloids from Cephalotaxus sinensis

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Discovery of Kalmane Diterpenoids as Potent Analgesics from the Flowers of Rhododendron dauricum

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Synthesis of Electron‐Deficient Tetrahydro‐ and Dihydroimidazo[1,2‐f]phenanthridines by Microwave‐Mediated IMDAF Reactions

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Total Syntheses of the Imidazo[1,2‐f]phenanthridine‐Containing Alkaloid Zephycandidine A

inferred← citeshttps://doi.org/10.1002/ejoc.70817openalex-snapshot

Copper‐Catalyzed Synthesis of Benzimidazole‐Fused Phenanthridines and Quinolines

inferred← citeshttps://doi.org/10.1007/978-3-642-36202-6_18-1openalex-snapshot

Amaryllidaceae Alkaloids

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One-pot synthesis of 2,3-diphenyl-6,7-dihydroimidazo[1,2-f]phenanthridin-8(5H)-ones catalyzed by CuI/l-proline

inferred← citeshttps://doi.org/10.1007/s11101-021-09790-0openalex-snapshot

The Amaryllidaceae alkaloids: an untapped source of acetylcholinesterase inhibitors

inferred← citeshttps://doi.org/10.1007/s11101-024-09931-1openalex-snapshot

Specialized metabolites of the genus Zephyranthes Herb.: a critical review on taxonomy and phytochemistry

inferred← citeshttps://doi.org/10.1016/bs.acr.2021.05.001openalex-snapshot

Acetylcholinesterase and human cancers

inferred← citeshttps://doi.org/10.1016/bs.alkal.2019.10.002openalex-snapshot

Chemodiversity, chemotaxonomy and chemoecology of Amaryllidaceae alkaloids

inferred← citeshttps://doi.org/10.1016/j.bioorg.2018.01.019openalex-snapshot

Ionic liquid-enabled synthesis, cholinesterase inhibitory activity, and molecular docking study of highly functionalized tetrasubstituted pyrrolidines

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Monoterpene indole alkaloids with acetylcholinesterase inhibitory activity from the leaves of Rauvolfia vomitoria

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Antiproliferative abietane quinone diterpenoids from the roots of Salvia deserta

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Chaetocochin J, an epipolythiodioxopiperazine alkaloid, induces apoptosis and autophagy in colorectal cancer via AMPK and PI3K/AKT/mTOR pathways

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Quinolizidine alkaloids from Sophora alopecuroides with anti-inflammatory and anti-tumor properties

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Peraksine derivatives with potential anti-inflammatory activities from the stems of Rauvolfia vomitoria

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Traceless imidate-directed oxidative decarboxylative arylation of electron-deficient aromatic rings enabled by Pd–Ag bimetallic catalysis

inferred← citeshttps://doi.org/10.1016/j.phytochem.2022.113449openalex-snapshot

Triterpenoids, steroids and other constituents from Euphorbia kansui and their anti-inflammatory and anti-tumor properties

inferred← citeshttps://doi.org/10.1016/j.phytochem.2022.113564openalex-snapshot

Structurally diverse alkaloids with nine frameworks from Zephyranthes candida and their acetylcholinesterase inhibitory and anti-inflammatory activities

inferred← citeshttps://doi.org/10.1016/j.tet.2025.134890openalex-snapshot

Progress in synthesis of imidazo-, benzoimidazo- and phenanthroimidazophenanthridine skeletons

inferred← citeshttps://doi.org/10.1016/j.tetlet.2020.151785openalex-snapshot

Synthesis of zephycandidine A from haemanthamine

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Synthesis of imidazo[1,2-f]phenanthridine derivatives under a metal- and base-free condition and their anticancer activity

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α-Glucosidase Inhibitory Activities and the Interaction Mechanism of Novel Spiro-Flavoalkaloids from YingDe Green Tea

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Structurally Diverse Diterpenoids from the Roots of Salvia deserta Based on Nine Different Skeletal Types

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.1c00062openalex-snapshot

Gelstriamine A, a Triamino Monoterpene Indole Alkaloid with a Caged 6/5/7/6/6/5 Scaffold and Analgesic Alkaloids from Gelsemium elegans Stems

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.7b00301openalex-snapshot

Acetylcholinesterase Inhibitory Alkaloids from the Whole Plants of Zephyranthes carinata

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Grayanane Diterpenoid Glucosides from the Leaves of Rhododendron micranthum and Their Bioactivities Evaluation

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Ru(II)-Catalyzed C–H Functionalization of 2-Arylbenzimidazoles with Iodonium Ylides: A Straightforward Access to Bridgehead Polycyclic N-Heterocycles

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Pd(OAc)2-Catalyzed Synthesis of Imidazo[1,2-f]phenanthridines via a Sequential Ullmann Coupling and Oxidative Coupling Dehydrogenation

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1,1′-Diarylethylene as a Key Additive for the Visible Light Synthesis of Bioactive Dihydrobenzo[a]phenanthridine Compounds

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Curtin–Hammett-Driven Intramolecular Cyclization of Heteroenyne–Allenes to Phenanthridine-Fused Quinazoliniminiums

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Tandem Palladium/Copper-Catalyzed Decarboxylative Approach to Benzoimidazo- and Imidazophenanthridine Skeletons

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Annulation of Phthalic Anhydrides with 2-Arylbenzimidazoles toward Phenanthridine-Fused Heterocycles: TBAI-Promoted Palladium Catalysis

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Synthesis of Imidazo[1,2‑ f ]phenanthridines by Recyclable Magnetic MOF-Catalyzed Coupling and Cyclization of 2‑(2-Bromoaryl)imidazoles with Cyclohexane-1,3-diones Followed by Aromatization

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Garbractin A, a Polycyclic Polyprenylated Acylphloroglucinol with a 4,11-dioxatricyclo[4.4.2.01,5]Dodecane Skeleton from Garcinia bracteata Fruits

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Flavonoids and alkaloids from the rhizomes of Zephyranthes ajax Hort. and their cytotoxicity

inferred← citeshttps://doi.org/10.1039/c8np00055gopenalex-snapshot

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inferred← citeshttps://doi.org/10.1039/d0qo00735hopenalex-snapshot

Spirodesertols A and B, two highly modified spirocyclic diterpenoids with an unprecedented 6-isopropyl-3 H -spiro[benzofuran-2,1′-cyclohexane] motif from Salvia deserta

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Palladium-catalyzed post-Ugi arylative dearomatization/Michael addition cascade towards plicamine analogues

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Alscholarines A and B, two rearranged monoterpene indole alkaloids from Alstonia scholaris

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Synthesis of π-extended imidazo[1,2- f ]phenanthridiniums: potent DNA intercalating agents

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Cytotoxic Agents in the Minor Alkaloid Groups of the Amaryllidaceae

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Tf2O-Promoted Morgan–Walls Reaction: From a Flexible Approach to Functionalized Phenanthridines and Quinazolines to the Short and Divergent Total Syntheses of Alkaloids

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ZYH005, a novel DNA intercalator, overcomes all-trans retinoic acid resistance in acute promyelocytic leukemia

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Micromorphology and anatomy of the flower of Zephyranthes candida (Amaryllidaceae)

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Determination of total phenol and total flavonoid, and antioxidant activities of chocolate leaves (Zephyranthes candida (Lindl.) Herb.)

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Natural Products Research in China From 2015 to 2016

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Sensing Magnetic Field and Intermolecular Interactions in Diamagnetic Solution Using Residual Dipolar Couplings of Zephycandidine

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Biosynthesis and Biological Activities of Newly Discovered Amaryllidaceae Alkaloids

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N-Tosylhydrazones as a versatile building block in C-C and C-N bond construction : cyclization and biological activities

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