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Why one-size-fits-all vaso-modulatory interventions fail to control glioma invasion: in silico insights

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Biological Waves: Single Species Models
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The 2007 WHO Classification of Tumours of the Central Nervous System
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The “go or grow” potential of gliomas is linked to the neuropeptide processing enzyme carboxypeptidase E and mediated by metabolic stress
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Hypoxia in cancer: significance and impact on clinical outcome
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Hypoxic Cell Waves Around Necrotic Cores in Glioblastoma: A Biomathematical Model and Its Therapeutic Implications
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Mechanisms of Glioma-Associated Neovascularization
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A review of mathematical models for the formation of vascular networks
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Vaso-occlusive and prothrombotic mechanisms associated with tumor hypoxia, necrosis, and accelerated growth in glioblastoma
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Spatial regulation of VEGF receptor endocytosis in angiogenesis
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Integrative mathematical oncology
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Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
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Angiogenesis in brain tumours
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The neurobiology of gliomas: from cell biology to the development of therapeutic approaches
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A neurocentric perspective on glioma invasion
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MGMT promoter methylation in malignant gliomas: ready for personalized medicine?
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Virtual brain tumours (gliomas) enhance the reality of medical imaging and highlight inadequacies of current therapy
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Variation in mitochondrial function in hypoxia-sensitive and hypoxia-tolerant human glioma cells
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A mathematical modelling tool for predicting survival of individual patients following resection of glioblastoma: a proof of principle
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Modulation of oxygen consumption rate and vascular endothelial growth factor mRNA expression in human malignant glioma cells by hypoxia
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A quantitative model for differential motility of gliomas in grey and white matter
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Investigation of the Migration/Proliferation Dichotomy and its Impact on Avascular Glioma Invasion
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Radiotherapy Plus Concomitant and Adjuvant Temozolomide for Glioblastoma
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Dynamic density functional theory of solid tumor growth: Preliminary models
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Modeling oxygen transport in surgical tissue transfer
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Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation
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Combining two strategies to improve perfusion and drug delivery in solid tumors
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Brain tissue oxygen pressure, carbon dioxide pressure and pH during ischemia
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Density-dependent quiescence in glioma invasion: instability in a simple reaction–diffusion model for the migration/proliferation dichotomy
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In silico tumor control induced via alternating immunostimulating and immunosuppressive phases
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A model to simulate tumour oxygenation and dynamic [18F]-Fmiso PET data
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Predicting the efficacy of radiotherapy in individual glioblastoma patients in vivo: a mathematical modeling approach
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Dynamics of VEGF matrix-retention in vascular network patterning
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'Go or Grow': the key to the emergence of invasion in tumour progression?
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Current status and future directions of anti-angiogenic therapy for gliomas
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The Interaction of Growth Rates and Diffusion Coefficients in a Three-dimensional Mathematical Model of Gliomas
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The Evolution of Mathematical Modeling of Glioma Proliferation and Invasion
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A method for estimating the oxygen consumption rate in multicellular tumour spheroids
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A patient-specific computational model of hypoxia-modulated radiation resistance in glioblastoma using 18 F-FMISO-PET
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Cancer therapeutic potential of combinatorial immuno- and vasomodulatory interventions
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Oedema‐based model for diffuse low‐grade gliomas: application to clinical cases under radiotherapy
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A mathematical model of glioma growth: the effect of chemotherapy on spatio‐temporal growth
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A mathematical model of glioma growth: the effect of extent of surgical resection
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Virtual glioblastoma: growth, migration and treatment in a three‐dimensional mathematical model
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Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia
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Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
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MATHEMATICAL MODELLING OF GLIOBLASTOMA TUMOUR DEVELOPMENT: A REVIEW
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The Role of Mechanical Forces in Tumor Growth and Therapy
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Transport of Molecules, Particles, and Cells in Solid Tumors
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Predictions of capillary oxygen transport in the presence of fluorocarbon additives
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Modeling the Spatial Distribution of Chronic Tumor Hypoxia: Implications for Experimental and Clinical Studies
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Tumor-dependent Kinetics of Partial Pressure of Oxygen Fluctuations during Air and Oxygen Breathing
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Pseudopalisades in Glioblastoma Are Hypoxic, Express Extracellular Matrix Proteases, and Are Formed by an Actively Migrating Cell Population
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Quantifying the Role of Angiogenesis in Malignant Progression of Gliomas: In Silico Modeling Integrates Imaging and Histology
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Increased Survival of Glioblastoma Patients Who Respond to Antiangiogenic Therapy with Elevated Blood Perfusion
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Coevolution of Solid Stress and Interstitial Fluid Pressure in Tumors During Progression: Implications for Vascular Collapse
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Hypoxia Is Important in the Biology and Aggression of Human Glial Brain Tumors
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Oscillatory dynamics in a model of vascular tumour growth - implications for chemotherapy
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Cost of Migration: Invasion of Malignant Gliomas and Implications for Treatment
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Antiangiogenics: The Potential Role of Integrating This Novel Treatment Modality With Chemoradiation for Solid Cancers
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Normalizing Tumor Microenvironment to Treat Cancer: Bench to Bedside to Biomarkers
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The Impact of Phenotypic Switching on Glioblastoma Growth and Invasion
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An Emerging Allee Effect Is Critical for Tumor Initiation and Persistence
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Model-Based Evaluation of Spontaneous Tumor Regression in Pilocytic Astrocytoma
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Estimating Dose Painting Effects in Radiotherapy: A Mathematical Model
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From Patient-Specific Mathematical Neuro-Oncology to Precision Medicine
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Modeling Tumor-Associated Edema in Gliomas during Anti-Angiogenic Therapy and Its Impact on Imageable Tumor
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A continuous model of angiogenesis: Initiation, extension, and maturation of new blood vessels modulated by vascular endothelial growth factor, angiopoietins, platelet-derived growth factor-B, and pericytes
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microRNA-451: A conditional switch controlling glioma cell proliferation and migration

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Microenvironmental Entropy Dynamics Analysis Reveals Novel Insights In Notch-Delta-Jagged Decision-Making Mechanism
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Temporally feathered intensity‐modulated radiation therapy: A planning technique to reduce normal tissue toxicity
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Cellular Automaton Modeling of Tumor Invasion
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Developmentally regulated signaling pathways in glioma invasion
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Multiscale modeling of glioma pseudopalisades: contributions from the tumor microenvironment
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Data driven modeling of pseudopalisade pattern formation
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A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression
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Antiangiogenic Therapy Efficacy Can Be Tumor-Size Dependent, as Mathematical Modeling Suggests
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Mathematical Modeling Shows That the Response of a Solid Tumor to Antiangiogenic Therapy Depends on the Type of Growth
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Mathematical Modelling of Glioblastomas Invasion within the Brain: A 3D Multi-Scale Moving-Boundary Approach
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A Novel Averaging Principle Provides Insights in the Impact of Intratumoral Heterogeneity on Tumor Progression
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Evaluation of Three Morphologically Distinct Virus-Like Particles as Nanocarriers for Convection-Enhanced Drug Delivery to Glioblastoma
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