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Glymphatic solute transport does not require bulk flow

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/aic.690330902openalex-snapshot
Hindered transport of large molecules in liquid‐filled pores
inferredcites →https://doi.org/10.1002/glia.20990openalex-snapshot
The perivascular astroglial sheath provides a complete covering of the brain microvessels: An electron microscopic 3D reconstruction
inferredcites →https://doi.org/10.1007/978-1-4614-4989-8_50openalex-snapshot
3D Analysis of Intracortical Microvasculature During Chronic Hypoxia in Mouse Brains
inferredcites →https://doi.org/10.1007/978-3-642-76894-1_9openalex-snapshot
Secretion and Bulk Flow of Interstitial Fluid
inferredcites →https://doi.org/10.1007/s00401-013-1145-2openalex-snapshot
Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer’s disease mouse models
inferredcites →https://doi.org/10.1007/s10439-011-0346-xopenalex-snapshot
The Effect of Pulsatile Flow on Intrathecal Drug Delivery in the Spinal Canal
inferredcites →https://doi.org/10.1016/0006-8993(85)91383-6openalex-snapshot
Evidence for a ‘Paravascular’ fluid circulation in the mammalian central nervous system, provided by the rapid distribution of tracer protein throughout the brain from the subarachnoid space
inferredcites →https://doi.org/10.1016/j.jbiomech.2006.05.031openalex-snapshot
Computational investigation of subject-specific cerebrospinal fluid flow in the third ventricle and aqueduct of Sylvius
inferredcites →https://doi.org/10.1016/j.jtbi.2005.07.005openalex-snapshot
Mechanisms to explain the reverse perivascular transport of solutes out of the brain
inferredcites →https://doi.org/10.1016/j.jtbi.2011.01.014openalex-snapshot
Fluid mechanics in the perivascular space
inferredcites →https://doi.org/10.1038/72256openalex-snapshot
Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke
inferredcites →https://doi.org/10.1038/srep15024openalex-snapshot
How astrocyte networks may contribute to cerebral metabolite clearance
inferredcites →https://doi.org/10.1042/cs20040251openalex-snapshot
Repeatability of non-invasive measurement of intracerebral pulse wave velocity using transcranial Doppler
inferredcites →https://doi.org/10.1073/pnas.0437946100openalex-snapshot
An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain
inferredcites →https://doi.org/10.1073/pnas.0509425103openalex-snapshot
In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space
inferredcites →https://doi.org/10.1080/10255840310001606116openalex-snapshot
Arterial Pulsation-driven Cerebrospinal Fluid Flow in the Perivascular Space: A Computational Model
inferredcites →https://doi.org/10.1085/jgp.201210883openalex-snapshot
Aquaporin-4–dependent K+ and water transport modeled in brain extracellular space following neuroexcitation
inferredcites →https://doi.org/10.1088/0034-4885/64/7/202openalex-snapshot
Diffusion and related transport mechanisms in brain tissue
inferredcites →https://doi.org/10.1111/bpa.12159openalex-snapshot
Failure of Perivascular Drainage of β‐amyloid in Cerebral Amyloid Angiopathy
inferredcites →https://doi.org/10.1111/j.1365-2990.2007.00926.xopenalex-snapshot
Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology
inferredcites →https://doi.org/10.1115/1.2768376openalex-snapshot
Mixing and Modes of Mass Transfer in the Third Cerebral Ventricle: A Computational Analysis
inferredcites →https://doi.org/10.1115/1.4003544openalex-snapshot
Approximation of Transient 1D Conduction in a Finite Domain Using Parametric Fractional Derivatives
inferredcites →https://doi.org/10.1126/science.1241224openalex-snapshot
Sleep Drives Metabolite Clearance from the Adult Brain
inferredcites →https://doi.org/10.1126/scitranslmed.3003748openalex-snapshot
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β
inferredcites →https://doi.org/10.1152/physrev.00027.2007openalex-snapshot
Diffusion in Brain Extracellular Space
inferredcites →https://doi.org/10.1172/jci103732openalex-snapshot
Factors Influencing the Concentration Gradient of Protein in Cerebrospinal Fluid12
inferredcites →https://doi.org/10.1177/016173460702900301openalex-snapshot
A Novel Noninvasive Technique for Pulse-Wave Imaging and Characterization of Clinically-Significant Vascular Mechanical Properties In Vivo
inferredcites →https://doi.org/10.1186/2045-8118-11-26openalex-snapshot
Mechanisms of fluid movement into, through and out of the brain: evaluation of the evidence
inferredcites →https://doi.org/10.1201/b11450openalex-snapshot
Astrocytes
inferredcites →https://doi.org/10.1212/wnl.26.1.1openalex-snapshot
Spinal descent of cerebrospinal fluid in man
inferredcites →https://doi.org/10.1259/bjr/66206791openalex-snapshot
Cerebrospinal fluid flow imaging by using phase-contrast MR technique
inferredcites →https://doi.org/10.1523/jneurosci.0257-08.2008openalex-snapshot
Aquaporin-4-Deficient Mice Have Increased Extracellular Space without Tortuosity Change
inferredcites →https://doi.org/10.1523/jneurosci.1592-13.2013openalex-snapshot
Cerebral Arterial Pulsation Drives Paravascular CSF–Interstitial Fluid Exchange in the Murine Brain
inferredcites →https://doi.org/10.1523/jneurosci.2294-04.2004openalex-snapshot
In VivoMeasurement of Brain Extracellular Space Diffusion by Cortical Surface Photobleaching
inferredcites →https://doi.org/10.1523/jneurosci.3287-09.2009openalex-snapshot
Correlations of Neuronal and Microvascular Densities in Murine Cortex Revealed by Direct Counting and Colocalization of Nuclei and Vessels
inferredcites →https://doi.org/10.3233/jad-142976openalex-snapshot
Is Vasomotion in Cerebral Arteries Impaired in Alzheimer’s Disease?
inferredcites →https://doi.org/10.3389/fnagi.2014.00251openalex-snapshot
The Cerebrovascular Basement Membrane: Role in the Clearance of β-amyloid and Cerebral Amyloid Angiopathy

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4570985openalex-extracted
A Framework for Detailed Numerical Simulation of Patient-Specific Cerebrospinal Fluid Flow for Relevant Clinical Applications
inferred← citeshttps://doi.org/10.1002/advs.202501502openalex-snapshot
Contrast Agent Clearance Dynamics and Diffusion in the Mouse Brain After Ventricular Administration
inferred← citeshttps://doi.org/10.1002/advs.202510684openalex-snapshot
Computational Fluid Dynamic Model Prediction of Enhanced Glymphatic Clearance in Response to Focused Ultrasound‐Mediated Blood‐Brain Barrier Opening
inferred← citeshttps://doi.org/10.1002/alz.70212openalex-snapshot
Imaging brain fluid dynamics and waste clearance involving perivascular spaces in cerebral small vessel disease
inferred← citeshttps://doi.org/10.1002/cnm.3412openalex-snapshot
Fast uncertainty quantification of tracer distribution in the brain interstitial fluid with multilevel and quasi Monte Carlo
inferred← citeshttps://doi.org/10.1002/exp.20250264openalex-snapshot
Arterial Perivascular Space‐Mediated Solute Transport in the Mouse Brain
inferred← citeshttps://doi.org/10.1002/glia.23138openalex-snapshot
Human and mouse cortical astrocytes differ in aquaporin-4 polarization toward microvessels
inferred← citeshttps://doi.org/10.1002/glia.23604openalex-snapshot
Aquaporin‐4‐independent volume dynamics of astroglial endfeet during cortical spreading depression
inferred← citeshttps://doi.org/10.1002/jmri.26892openalex-snapshot
Glymphatic imaging using MRI
inferred← citeshttps://doi.org/10.1002/jmri.28759openalex-snapshot
Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 “ ISMRM Imaging Neurofluids Study group” Workshop in Rome
inferred← citeshttps://doi.org/10.1002/jmri.29040openalex-snapshot
Glymphatic Imaging in Pediatrics
inferred← citeshttps://doi.org/10.1002/jnr.24082openalex-snapshot
A transcriptome‐based assessment of the astrocytic dystrophin‐associated complex in the developing human brain
inferred← citeshttps://doi.org/10.1002/nbm.5029openalex-snapshot
Cerebrospinal fluid turnover as a driver of brain clearance
inferred← citeshttps://doi.org/10.1002/nbm.70282openalex-snapshot
Exploring the Role of Vascular Factors and Tissue Properties in Pulsatile Brain Deformation
inferred← citeshttps://doi.org/10.1007/164_2017_37openalex-snapshot
Metabolite Clearance During Wakefulness and Sleep
inferred← citeshttps://doi.org/10.1007/978-1-4939-8709-2_3openalex-snapshot
Meningeal Immunity, Drainage, and Tertiary Lymphoid Structure Formation
inferred← citeshttps://doi.org/10.1007/978-3-030-04996-6_9openalex-snapshot
Modelling of Cerebrospinal Fluid Flow by Computational Fluid Dynamics
inferred← citeshttps://doi.org/10.1007/978-3-031-05946-9_6openalex-snapshot
Brain Interstitial Structure Revealed Through Diffusive Spread of Molecules
inferred← citeshttps://doi.org/10.1007/978-3-031-39558-1_7openalex-snapshot
Cerebrospinal and Interstitial Fluids: Production, Outflow, and Circulation
inferred← citeshttps://doi.org/10.1007/978-3-031-39558-1_8openalex-snapshot
Emerging Insights into the Interstitial Distribution of Neuraxial Therapeutics via the Cerebrospinal Fluid Compartment
inferred← citeshttps://doi.org/10.1007/978-3-031-92598-6_4openalex-snapshot
Cerebrospinal Fluid
inferred← citeshttps://doi.org/10.1007/978-3-032-00679-0_8openalex-snapshot
Two-compartment modeling of tracer transport in the brain
inferred← citeshttps://doi.org/10.1007/978-3-319-67798-9_6openalex-snapshot
Brain Interstitial Structure Revealed Through Diffusive Spread of Molecules
inferred← citeshttps://doi.org/10.1007/s00018-024-05277-1openalex-snapshot
Is CAA a perivascular brain clearance disease? A discussion of the evidence to date and outlook for future studies
inferred← citeshttps://doi.org/10.1007/s00109-018-1634-9openalex-snapshot
Brain drains: new insights into brain clearance pathways from lymphatic biology
inferred← citeshttps://doi.org/10.1007/s00234-021-02718-7openalex-snapshot
Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology
inferred← citeshttps://doi.org/10.1007/s00285-024-02092-xopenalex-snapshot
Flow in temporally and spatially varying porous media: a model for transport of interstitial fluid in the brain
inferred← citeshttps://doi.org/10.1007/s00285-024-02154-0openalex-snapshot
Directional flow in perivascular networks: mixed finite elements for reduced-dimensional models on graphs
inferred← citeshttps://doi.org/10.1007/s00348-023-03719-3openalex-snapshot
Image analysis techniques for in vivo quantification of cerebrospinal fluid flow
inferred← citeshttps://doi.org/10.1007/s00401-018-1812-4openalex-snapshot
The role of brain barriers in fluid movement in the CNS: is there a ‘glymphatic’ system?
inferred← citeshttps://doi.org/10.1007/s00401-018-1916-xopenalex-snapshot
Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain
inferred← citeshttps://doi.org/10.1007/s00466-024-02471-7openalex-snapshot
Modelling and simulation of anisotropic growth in brain tumours through poroelasticity: A study of ventricular compression and therapeutic protocols
inferred← citeshttps://doi.org/10.1007/s10237-019-01253-yopenalex-snapshot
Computational modelling of fluid and solute transport in the brain
inferred← citeshttps://doi.org/10.1007/s10237-021-01474-0openalex-snapshot
Phase offset between arterial pulsations and subarachnoid space pressure fluctuations are unlikely to drive periarterial cerebrospinal fluid flow
inferred← citeshttps://doi.org/10.1007/s10237-022-01602-4openalex-snapshot
Coupling solid and fluid stresses with brain tumour growth and white matter tract deformations in a neuroimaging-informed model
inferred← citeshttps://doi.org/10.1007/s11095-022-03175-4openalex-snapshot
A Semi-Physiological Three-Compartment Model Describes Brain Uptake Clearance and Efflux of Sucrose and Mannitol after IV Injection in Awake Mice
inferred← citeshttps://doi.org/10.1007/s11940-024-00811-9openalex-snapshot
Treatment of Obstructive Sleep Apnea in patients with Alzheimer’s Disease: role of Continuous Positive Airway Pressure therapy
inferred← citeshttps://doi.org/10.1007/s13139-020-00665-4openalex-snapshot
Brain Glymphatic/Lymphatic Imaging by MRI and PET
inferred← citeshttps://doi.org/10.1016/b978-0-12-805353-9.00067-xopenalex-snapshot
Cerebrospinal Fluid Dynamics and Intrathecal Delivery
inferred← citeshttps://doi.org/10.1016/b978-0-12-822963-7.00236-xopenalex-snapshot
Sleep and the glymphatic system
inferred← citeshttps://doi.org/10.1016/b978-0-323-93273-8.00003-1openalex-snapshot
Cerebrospinal Fluid
inferred← citeshttps://doi.org/10.1016/b978-0-443-22273-3.00029-8openalex-snapshot
Fluid management in neurocritical care patients
inferred← citeshttps://doi.org/10.1016/j.addr.2021.03.002openalex-snapshot
Harnessing cerebrospinal fluid circulation for drug delivery to brain tissues
inferred← citeshttps://doi.org/10.1016/j.addr.2022.114338openalex-snapshot
Intrathecal delivery and its applications in leptomeningeal disease
inferred← citeshttps://doi.org/10.1016/j.brainres.2018.02.017openalex-snapshot
Cerebral microvascular abnormalities in patients with idiopathic intracranial hypertension
inferred← citeshttps://doi.org/10.1016/j.cell.2024.11.027openalex-snapshot
Norepinephrine-mediated slow vasomotion drives glymphatic clearance during sleep
inferred← citeshttps://doi.org/10.1016/j.chaos.2023.114334openalex-snapshot
A machine learning method to explore the glymphatic system via poroelastodynamics
inferred← citeshttps://doi.org/10.1016/j.cma.2023.116449openalex-snapshot
Image-guided subject-specific modeling of glymphatic transport and amyloid deposition
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2019.07.029openalex-snapshot
Alcohol promotes waste clearance in the CNS via brain vascular reactivity
inferred← citeshttps://doi.org/10.1016/j.isci.2022.104258openalex-snapshot
A network model of glymphatic flow under different experimentally-motivated parametric scenarios
inferred← citeshttps://doi.org/10.1016/j.isci.2022.104987openalex-snapshot
The glymphatic system: Current understanding and modeling
inferred← citeshttps://doi.org/10.1016/j.jbiomech.2019.04.030openalex-snapshot
The effects of variation in the arterial pulse waveform on perivascular flow
inferred← citeshttps://doi.org/10.1016/j.jbiomech.2021.110278openalex-snapshot
Mechanisms of tracer transport in cerebral perivascular spaces
inferred← citeshttps://doi.org/10.1016/j.jconrel.2018.08.006openalex-snapshot
Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose-response, and mechanisms of delivery
inferred← citeshttps://doi.org/10.1016/j.jmr.2018.12.009openalex-snapshot
Phase contrast MRI of creeping flows using stimulated echo
inferred← citeshttps://doi.org/10.1016/j.jtbi.2021.110709openalex-snapshot
Cerebrospinal fluid flow driven by arterial pulsations in axisymmetric perivascular spaces: Analogy with Taylor’s swimming sheet
inferred← citeshttps://doi.org/10.1016/j.jtbi.2022.111103openalex-snapshot
Perivascular pumping in the mouse brain: Improved boundary conditions reconcile theory, simulation, and experiment
inferred← citeshttps://doi.org/10.1016/j.lfs.2018.03.057openalex-snapshot
Characterizing the glymphatic influx by utilizing intracisternal infusion of fluorescently conjugated cadaverine
inferred← citeshttps://doi.org/10.1016/j.mri.2018.11.007openalex-snapshot
Isotropically weighted intravoxel incoherent motion brain imaging at 7T
inferred← citeshttps://doi.org/10.1016/j.mri.2023.01.003openalex-snapshot
Abnormalities in cardiac-induced brain tissue deformations are now detectable with MRI: A case-report of a patient who underwent craniotomy after trauma
inferred← citeshttps://doi.org/10.1016/j.mric.2021.01.002openalex-snapshot
Neurofluid as Assessed by Diffusion-Weighted Imaging
inferred← citeshttps://doi.org/10.1016/j.msard.2024.105456openalex-snapshot
The glymphatic system and multiple sclerosis: An evolving connection
inferred← citeshttps://doi.org/10.1016/j.nbd.2018.07.017openalex-snapshot
Protein biomarkers of epileptogenicity after traumatic brain injury
inferred← citeshttps://doi.org/10.1016/j.nbd.2022.105750openalex-snapshot
Cerebral small vessel disease alters neurovascular unit regulation of microcirculation integrity involved in vascular cognitive impairment
inferred← citeshttps://doi.org/10.1016/j.nbd.2022.105986openalex-snapshot
Fluid dynamics in aging-related dementias
inferred← citeshttps://doi.org/10.1016/j.nbd.2025.106791openalex-snapshot
New perspectives on the glymphatic system and the relationship between glymphatic system and neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.nbd.2025.106877openalex-snapshot
Vascular and glymphatic dysfunction as drivers of cognitive impairment in Alzheimer's disease: Insights from computational approaches
inferred← citeshttps://doi.org/10.1016/j.nbd.2026.107515openalex-snapshot
The Glymphatic system: A key mechanism linking sleep to brain health and diseases
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2026.106819openalex-snapshot
AQP4-mediated glymphatic clearance: Sleep, neurodegeneration, and the translational gap
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2019.116466openalex-snapshot
Validating faster DENSE measurements of cardiac-induced brain tissue expansion as a potential tool for investigating cerebral microvascular pulsations
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2020.116581openalex-snapshot
Cardiac and respiration-induced brain deformations in humans quantified with high-field MRI
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2021.118078openalex-snapshot
Strain Tensor Imaging: Cardiac-induced brain tissue deformation in humans quantified with high-field MRI
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2022.119329openalex-snapshot
Imaging perivascular space structure and function using brain MRI
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2025.121490openalex-snapshot
Synchronous assessment of CSF and cerebral arteriovenous flow interactions across ultra-low, low, respiratory, and cardiac frequencies using real-time phase-contrast MRI
inferred← citeshttps://doi.org/10.1016/j.neuron.2018.09.022openalex-snapshot
The Meningeal Lymphatic System: A New Player in Neurophysiology
inferred← citeshttps://doi.org/10.1016/j.neuron.2019.10.033openalex-snapshot
Vasomotion as a Driving Force for Paravascular Clearance in the Awake Mouse Brain
inferred← citeshttps://doi.org/10.1016/j.neuron.2025.10.036openalex-snapshot
Resolving the mysteries of brain clearance and immune surveillance
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2019.06.032openalex-snapshot
The Movement of Cerebrospinal Fluid and Its Relationship with Substances Behavior in Cerebrospinal and Interstitial Fluid
inferred← citeshttps://doi.org/10.1016/j.pneurobio.2017.05.002openalex-snapshot
Where are we? The anatomy of the murine cortical meninges revisited for intravital imaging, immunology, and clearance of waste from the brain
inferred← citeshttps://doi.org/10.1016/j.tins.2020.04.003openalex-snapshot
The Brain’s Glymphatic System: Current Controversies
inferred← citeshttps://doi.org/10.1016/j.wneu.2017.12.101openalex-snapshot
Gadobutrol and the End of the Tap Test
inferred← citeshttps://doi.org/10.1016/j.wneu.2024.07.062openalex-snapshot
The Glymphatic System and Subarachnoid Lymphatic-Like Membrane: Recent Developments in Cerebrospinal Fluid Research
inferred← citeshttps://doi.org/10.1017/jfm.2021.277openalex-snapshot
Peristaltic pumping in thin non-axisymmetric annular tubes
inferred← citeshttps://doi.org/10.1017/jfm.2026.11573openalex-snapshot
Enhanced Taylor–Aris dispersion in slender pulsatile annular channels: implications for perivascular solute transport
inferred← citeshttps://doi.org/10.1017/jfm.2026.12046openalex-snapshot
Oscillatory flow and steady streaming of cerebrospinal fluid in cranial subarachnoid space
inferred← citeshttps://doi.org/10.1021/acs.bioconjchem.8b00548openalex-snapshot
Passive Immunotherapies for Central Nervous System Disorders: Current Delivery Challenges and New Approaches
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.4c00026openalex-snapshot
Quantifying the Lymphatic Transport of Model Therapeutics from the Brain in Rats
inferred← citeshttps://doi.org/10.1038/ni.3666openalex-snapshot
The movers and shapers in immune privilege of the CNS
inferred← citeshttps://doi.org/10.1038/nrneurol.2017.188openalex-snapshot
Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
inferred← citeshttps://doi.org/10.1038/s41380-025-03126-6openalex-snapshot
Perceiving traumatic brain injury from glymphatic system
inferred← citeshttps://doi.org/10.1038/s41380-026-03750-wopenalex-snapshot
The glymphatic system in sleep: a nexus of waste clearance, brain homeostasis, and disease intervention
inferred← citeshttps://doi.org/10.1038/s41467-018-07318-3openalex-snapshot
Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension
inferred← citeshttps://doi.org/10.1038/s41467-023-36643-5openalex-snapshot
Sleep cycle-dependent vascular dynamics in male mice and the predicted effects on perivascular cerebrospinal fluid flow and solute transport
inferred← citeshttps://doi.org/10.1038/s41573-022-00500-9openalex-snapshot
The glymphatic system: implications for drugs for central nervous system diseases
inferred← citeshttps://doi.org/10.1038/s41582-020-0312-zopenalex-snapshot
Perivascular spaces in the brain: anatomy, physiology and pathology
inferred← citeshttps://doi.org/10.1038/s41583-021-00454-8openalex-snapshot
Molecular mechanisms of brain water transport
inferred← citeshttps://doi.org/10.1038/s41593-024-01638-yopenalex-snapshot
Brain clearance is reduced during sleep and anesthesia
inferred← citeshttps://doi.org/10.1038/s41593-025-01898-2openalex-snapshot
Reply to: A curious concept of CNS clearance
inferred← citeshttps://doi.org/10.1038/s41597-026-06564-1openalex-snapshot
Human brain MRI data of intrathecally injected tracer evolution over 72 hours for data-integrated simulations
inferred← citeshttps://doi.org/10.1038/s41598-017-06748-1openalex-snapshot
Hydro-dynamic Solute Transport under Two-Phase Flow Conditions
inferred← citeshttps://doi.org/10.1038/s41598-017-13455-4openalex-snapshot
The ultrastructure of spinal cord perivascular spaces: Implications for the circulation of cerebrospinal fluid
inferred← citeshttps://doi.org/10.1038/s41598-019-44938-1openalex-snapshot
MRI of Whole Rat Brain Perivascular Network Reveals Role for Ventricles in Brain Waste Clearance
inferred← citeshttps://doi.org/10.1038/s41598-020-59045-9openalex-snapshot
Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System
inferred← citeshttps://doi.org/10.1038/s41598-020-66042-5openalex-snapshot
Apparent diffusion coefficient estimates based on 24 hours tracer movement support glymphatic transport in human cerebral cortex
inferred← citeshttps://doi.org/10.1038/s41598-020-66887-wopenalex-snapshot
Arterial pulsations drive oscillatory flow of CSF but not directional pumping
inferred← citeshttps://doi.org/10.1038/s41598-020-77787-4openalex-snapshot
Peristaltic flow in the glymphatic system
inferred← citeshttps://doi.org/10.1038/s41598-021-83951-1openalex-snapshot
Dispersion as a waste-clearance mechanism in flow through penetrating perivascular spaces in the brain
inferred← citeshttps://doi.org/10.1038/s41598-021-95306-xopenalex-snapshot
Brain solute transport is more rapid in periarterial than perivenous spaces
inferred← citeshttps://doi.org/10.1038/s41598-022-15034-8openalex-snapshot
Immediate impact of yogic breathing on pulsatile cerebrospinal fluid dynamics
inferred← citeshttps://doi.org/10.1038/s41598-022-15109-6openalex-snapshot
Cortical waste clearance in normal and restricted sleep with potential runaway tau buildup in Alzheimer’s disease
inferred← citeshttps://doi.org/10.1038/s41598-022-19157-wopenalex-snapshot
Investigating molecular transport in the human brain from MRI with physics-informed neural networks
inferred← citeshttps://doi.org/10.1038/s41598-023-34850-0openalex-snapshot
Perivascular network segmentations derived from high-field MRI and their implications for perivascular and parenchymal mass transport in the rat brain
inferred← citeshttps://doi.org/10.1038/s41598-025-97631-xopenalex-snapshot
Arterial pulsations and transmantle pressure synergetically drive glymphatic flow
inferred← citeshttps://doi.org/10.1038/s42003-022-03037-0openalex-snapshot
Importance of CSF-based Aβ clearance with age in humans increases with declining efficacy of blood-brain barrier/proteolytic pathways
inferred← citeshttps://doi.org/10.1039/d3bm00027copenalex-snapshot
Solute transport in the brain tissue: what are the key biophysical parameters tying in vivo and in vitro studies together?
inferred← citeshttps://doi.org/10.1042/cs20160381openalex-snapshot
Perivascular spaces, glymphatic dysfunction, and small vessel disease
inferred← citeshttps://doi.org/10.1051/medsci/2018309openalex-snapshot
Système lymphatique et cerveau
inferred← citeshttps://doi.org/10.1063/5.0160334openalex-snapshot
The directional flow generated by peristalsis in perivascular networks—Theoretical and numerical reduced-order descriptions
inferred← citeshttps://doi.org/10.1073/pnas.1706942114openalex-snapshot
Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow
inferred← citeshttps://doi.org/10.1073/pnas.1914017117openalex-snapshot
Imaging the effect of the circadian light–dark cycle on the glymphatic system in awake rats
inferred← citeshttps://doi.org/10.1073/pnas.2105328118openalex-snapshot
On the microstructural origin of brain white matter hydraulic permeability
inferred← citeshttps://doi.org/10.1084/jem.20171406openalex-snapshot
Alzheimer’s disease: A matter of blood–brain barrier dysfunction?
inferred← citeshttps://doi.org/10.1084/jem.20172031openalex-snapshot
The amazing brain drain
inferred← citeshttps://doi.org/10.1093/brain/awx191openalex-snapshot
Glymphatic MRI in idiopathic normal pressure hydrocephalus
inferred← citeshttps://doi.org/10.1093/cvr/cvy113openalex-snapshot
Understanding the role of the perivascular space in cerebral small vessel disease
inferred← citeshttps://doi.org/10.1093/oxfordhb/9780197602751.013.60openalex-snapshot
Brain Clearance, Sleep, and Circadian Rhythms
inferred← citeshttps://doi.org/10.1093/pnasnexus/pgae548openalex-snapshot
Fluid flow and amyloid transport and aggregation in the brain interstitial space
inferred← citeshttps://doi.org/10.1096/fj.201700999openalex-snapshot
The “glymphatic” mechanism for solute clearance in Alzheimer's disease: game changer or unproven speculation?
inferred← citeshttps://doi.org/10.1097/rli.0000000000001120openalex-snapshot
Decoding Brain Development and Aging
inferred← citeshttps://doi.org/10.1098/rsfs.2024.0044openalex-snapshot
In vivo magnetic resonance imaging of the interstitial pressure gradients (pgMRI) using a pulsatile poroelastic computational model
inferred← citeshttps://doi.org/10.1098/rsfs.2024.0058openalex-snapshot
The pulsing brain: state of the art and an interdisciplinary perspective
inferred← citeshttps://doi.org/10.1098/rsif.2019.0572openalex-snapshot
Fluid dynamics of cerebrospinal fluid flow in perivascular spaces
inferred← citeshttps://doi.org/10.1098/rsif.2020.0593openalex-snapshot
Surface periarterial spaces of the mouse brain are open, not porous
inferred← citeshttps://doi.org/10.1098/rsif.2021.0812openalex-snapshot
A hydraulic resistance model for interstitial fluid flow in the brain
inferred← citeshttps://doi.org/10.1098/rsif.2022.0321openalex-snapshot
Effect of cilia-induced surface velocity on cerebrospinal fluid exchange in the lateral ventricles
inferred← citeshttps://doi.org/10.1098/rsif.2023.0288openalex-snapshot
Perivascular pumping of cerebrospinal fluid in the brain with a valve mechanism
inferred← citeshttps://doi.org/10.1101/2020.07.02.183608openalex-snapshot
Realistic boundary conditions for perivascular pumping in the mouse brain reconcile theory, simulation, and experiment
inferred← citeshttps://doi.org/10.1101/2021.03.29.437406openalex-snapshot
Coupling between cerebrovascular oscillations and CSF flow fluctuation during wakefulness: An fMRI study
inferred← citeshttps://doi.org/10.1101/2022.07.14.500017openalex-snapshot
Sleep cycle-dependent vascular dynamics enhance perivascular cerebrospinal fluid flow and solute transport
inferred← citeshttps://doi.org/10.1101/2025.01.30.635680openalex-snapshot
In-silico molecular enrichment and clearance of the human intracranial space
inferred← citeshttps://doi.org/10.1101/2025.03.21.644478openalex-snapshot
Hyperspectral Sensing for High-Throughput Screening of Boron Tolerance in Grapevines
inferred← citeshttps://doi.org/10.1101/2025.03.22.643151openalex-snapshot
Decoding Brain Interstitial Transport In Vivo: A Fully Validated Bottom-Up Mechanistic Prediction Framework
inferred← citeshttps://doi.org/10.1101/2025.04.02.646802openalex-snapshot
A new framework for analyzing mass transport in cortical brain tissue at <10 nm resolution
inferred← citeshttps://doi.org/10.1101/2025.07.23.25331971openalex-snapshot
Human brain MRI data of CSF tracer evolution over 72h for data-integrated simulations
inferred← citeshttps://doi.org/10.1103/m9ys-76scopenalex-snapshot
Brain pulsations enhance cerebrospinal fluid flow in perivascular spaces
inferred← citeshttps://doi.org/10.1103/physrevfluids.6.070501openalex-snapshot
Brain cerebrospinal fluid flow
inferred← citeshttps://doi.org/10.1109/icbme57741.2022.10053012openalex-snapshot
Develop a numerical model of the Glymphatic system to investigate the flow patterns and transport processes
inferred← citeshttps://doi.org/10.1109/jstqe.2020.3045834openalex-snapshot
Biophotonic Strategies of Measurement and Stimulation of the Cranial and the Extracranial Lymphatic Drainage Function
inferred← citeshttps://doi.org/10.1111/pcn.13557openalex-snapshot
Gray matter reserve determines glymphatic system function in young‐onset Alzheimer's disease: Evidenced by DTI‐ALPS and compared with age‐matched controls
inferred← citeshttps://doi.org/10.1113/ep087424openalex-snapshot
Paravascular spaces: entry to or exit from the brain?
inferred← citeshttps://doi.org/10.1113/jp275105openalex-snapshot
Intrathecal antibody distribution in the rat brain: surface diffusion, perivascular transport and osmotic enhancement of delivery
inferred← citeshttps://doi.org/10.1113/jp277635openalex-snapshot
CrossTalk proposal: The glymphatic system supports convective exchange of cerebrospinal fluid and brain interstitial fluid that is mediated by perivascular aquaporin‐4
inferred← citeshttps://doi.org/10.1115/1.4065556openalex-snapshot
How Irregular Geometry and Flow Waveform Affect Pulsating Arterial Mass Transfer
inferred← citeshttps://doi.org/10.1126/science.aax5440openalex-snapshot
Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep
inferred← citeshttps://doi.org/10.1134/s0022093023010015openalex-snapshot
Lymphatic Drainage System of the Brain: a New Player in Neuroscience
inferred← citeshttps://doi.org/10.1140/epjp/s13360-021-01700-9openalex-snapshot
Toward label-free imaging of brain vasculature: frame-by-frame spatial adaptive filtration and adaptive PIV approaches
inferred← citeshttps://doi.org/10.1146/annurev-fluid-120720-011638openalex-snapshot
Cerebrospinal Fluid Flow
inferred← citeshttps://doi.org/10.1148/radiol.2021202043openalex-snapshot
Current Concepts in Intracranial Interstitial Fluid Transport and the Glymphatic System: Part I—Anatomy and Physiology
inferred← citeshttps://doi.org/10.1152/physiol.00015.2022openalex-snapshot
Physiology of Glymphatic Solute Transport and Waste Clearance from the Brain
inferred← citeshttps://doi.org/10.1152/physrev.00031.2020openalex-snapshot
Fluid transport in the brain
inferred← citeshttps://doi.org/10.1152/physrev.00050.2017openalex-snapshot
Blood-Brain Barrier: From Physiology to Disease and Back
inferred← citeshttps://doi.org/10.1159/000486955openalex-snapshot
Associations of Pulse and Blood Pressure with Hippocampal Volume by APOE and Cognitive Phenotype: The Alzheimer’s Disease Neuroimaging Initiative (ADNI)
inferred← citeshttps://doi.org/10.1159/000490349openalex-snapshot
The Glymphatic System and Waste Clearance with Brain Aging: A Review
inferred← citeshttps://doi.org/10.1172/jci.insight.121537openalex-snapshot
Brain-wide glymphatic enhancement and clearance in humans assessed with MRI
inferred← citeshttps://doi.org/10.1172/jci90603openalex-snapshot
Understanding the functions and relationships of the glymphatic system and meningeal lymphatics
inferred← citeshttps://doi.org/10.1177/0271678x17737984openalex-snapshot
Paravascular spaces at the brain surface: Low resistance pathways for cerebrospinal fluid flow
inferred← citeshttps://doi.org/10.1177/0271678x18754732openalex-snapshot
Reduced spinal cord parenchymal cerebrospinal fluid circulation in experimental autoimmune encephalomyelitis
inferred← citeshttps://doi.org/10.1177/0271678x20910302openalex-snapshot
Assessment of vascular stiffness in the internal carotid artery proximal to the carotid canal in Alzheimer’s disease using pulse wave velocity from low rank reconstructed 4D flow MRI
inferred← citeshttps://doi.org/10.1177/0271678x20985946openalex-snapshot
Understanding the brain uptake and permeability of small molecules through the BBB: A technical overview
inferred← citeshttps://doi.org/10.1177/0271678x21992462openalex-snapshot
Cerebrovascular phenotypes in mouse models of Alzheimer’s disease
inferred← citeshttps://doi.org/10.1177/0271678x221074639openalex-snapshot
Coupling between cerebrovascular oscillations and CSF flow fluctuations during wakefulness: An fMRI study
inferred← citeshttps://doi.org/10.1177/0271678x261454165openalex-snapshot
A perivascular perspective on the immune impacts in cerebral amyloid angiopathy
inferred← citeshttps://doi.org/10.1177/1073858417691030openalex-snapshot
The Glymphatic Pathway: Waste Removal from the CNS via Cerebrospinal Fluid Transport
inferred← citeshttps://doi.org/10.1177/1073858418775027openalex-snapshot
Fluid Dynamics Inside the Brain Barrier: Current Concept of Interstitial Flow, Glymphatic Flow, and Cerebrospinal Fluid Circulation in the Brain
inferred← citeshttps://doi.org/10.1177/27325016231226301openalex-snapshot
The Anatomy and Physiology of the Glymphatic System and Its Role in Craniectomies and Syndrome of the Trephined
inferred← citeshttps://doi.org/10.1186/s10194-024-01741-2openalex-snapshot
The glymphatic system in migraine and other headaches
inferred← citeshttps://doi.org/10.1186/s12987-017-0052-7openalex-snapshot
Brain barriers and brain fluid research in 2016: advances, challenges and controversies
inferred← citeshttps://doi.org/10.1186/s12987-017-0063-4openalex-snapshot
Barrier dysfunction or drainage reduction: differentiating causes of CSF protein increase
inferred← citeshttps://doi.org/10.1186/s12987-018-0098-1openalex-snapshot
Fluid outflow in the rat spinal cord: the role of perivascular and paravascular pathways
inferred← citeshttps://doi.org/10.1186/s12987-018-0103-8openalex-snapshot
Is bulk flow plausible in perivascular, paravascular and paravenous channels?
inferred← citeshttps://doi.org/10.1186/s12987-018-0105-6openalex-snapshot
Pulsatile flow drivers in brain parenchyma and perivascular spaces: a resistance network model study
inferred← citeshttps://doi.org/10.1186/s12987-018-0113-6openalex-snapshot
Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood–brain barrier
inferred← citeshttps://doi.org/10.1186/s12987-019-0126-9openalex-snapshot
Analysis of convective and diffusive transport in the brain interstitium
inferred← citeshttps://doi.org/10.1186/s12987-019-0127-8openalex-snapshot
Effect of extradural constriction on CSF flow in rat spinal cord
inferred← citeshttps://doi.org/10.1186/s12987-019-0129-6openalex-snapshot
Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases
inferred← citeshttps://doi.org/10.1186/s12987-019-0132-yopenalex-snapshot
Dispersion in porous media in oscillatory flow between flat plates: applications to intrathecal, periarterial and paraarterial solute transport in the central nervous system
inferred← citeshttps://doi.org/10.1186/s12987-019-0140-yopenalex-snapshot
Hydraulic resistance of periarterial spaces in the brain
inferred← citeshttps://doi.org/10.1186/s12987-019-0152-7openalex-snapshot
Uncertainty quantification of parenchymal tracer distribution using random diffusion and convective velocity fields
inferred← citeshttps://doi.org/10.1186/s12987-020-00189-1openalex-snapshot
Intracranial pressure elevation alters CSF clearance pathways
inferred← citeshttps://doi.org/10.1186/s12987-020-00214-3openalex-snapshot
Functional hyperemia drives fluid exchange in the paravascular space
inferred← citeshttps://doi.org/10.1186/s12987-021-00279-8openalex-snapshot
Tachycardia and hypertension enhance tracer efflux from the spinal cord
inferred← citeshttps://doi.org/10.1186/s12987-021-00282-zopenalex-snapshot
The glymphatic hypothesis: the theory and the evidence
inferred← citeshttps://doi.org/10.1186/s12987-021-00290-zopenalex-snapshot
Quantitative analysis of macroscopic solute transport in the murine brain
inferred← citeshttps://doi.org/10.1186/s12987-022-00326-yopenalex-snapshot
Arterial vasodilation drives convective fluid flow in the brain: a poroelastic model
inferred← citeshttps://doi.org/10.1186/s12987-023-00443-2openalex-snapshot
Disentangling the impact of cerebrospinal fluid formation and neuronal activity on solute clearance from the brain
inferred← citeshttps://doi.org/10.1186/s12987-023-00445-0openalex-snapshot
Pulsatile cerebral paraarterial flow by peristalsis, pressure and directional resistance
inferred← citeshttps://doi.org/10.1186/s12987-024-00518-8openalex-snapshot
Large-scale in-silico analysis of CSF dynamics within the subarachnoid space of the optic nerve
inferred← citeshttps://doi.org/10.1186/s12987-024-00612-xopenalex-snapshot
Transmantle pressure under the influence of free breathing: non-invasive quantification of the aqueduct pressure gradient in healthy adults
inferred← citeshttps://doi.org/10.1186/s12987-025-00668-3openalex-snapshot
Perivascular interactions and tissue properties modulate directional glymphatic transport in the brain
inferred← citeshttps://doi.org/10.1186/s12987-025-00676-3openalex-snapshot
Are diurnal variations in glymphatic clearance driven by circadian regulation of Aquaporin-4 expression?
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