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Polydatin protects the respiratory system from PM2.5 exposure

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Polydatin, A Natural Precursor of Resveratrol, Induces β-Defensin Production and Reduces Inflammatory Response

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Development of mesoporous silica-based nanoparticles with controlled release capability for cancer therapy

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Redox activity of airborne particulate matter at different sites in the Los Angeles Basin

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Peak expiratory flow, breath rate and blood pressure in adults with changes in particulate matter air pollution during the Beijing Olympics: A panel study

inferredcites →https://doi.org/10.1016/j.fct.2014.07.022openalex-snapshot

Protective effect of polydatin, a natural precursor of resveratrol, against cisplatin-induced toxicity in rats

inferredcites →https://doi.org/10.1016/j.jchromb.2010.11.012openalex-snapshot

Investigation of piceid metabolites in rat by liquid chromatography tandem mass spectrometry

inferredcites →https://doi.org/10.1016/j.jpba.2005.08.027openalex-snapshot

HPLC determination of polydatin in rat biological matrices: Application to pharmacokinetic studies

inferredcites →https://doi.org/10.1016/j.tibs.2008.12.008openalex-snapshot

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

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Short term inhalation toxicity of a liquid aerosol of glutaraldehyde-coated CdS/Cd(OH)2 core shell quantum dots in rats

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China tackles the health effects of air pollution

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The death toll from air-pollution sources

inferredcites →https://doi.org/10.1038/jes.2013.25openalex-snapshot

Airway inflammation and oxidative potential of air pollutant particles in a pediatric asthma panel

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Downregulation of specific miRNAs in hyperdiploid multiple myeloma mimics the oncogenic effect of IgH translocations occurring in the non-hyperdiploid subtype

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Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice

inferredcites →https://doi.org/10.1038/nrcardio.2015.152openalex-snapshot

Environmental factors in cardiovascular disease

inferredcites →https://doi.org/10.1038/nrd2060openalex-snapshot

Therapeutic potential of resveratrol: the in vivo evidence

inferredcites →https://doi.org/10.1038/srep16936openalex-snapshot

The preferential accumulation of heavy metals in different tissues following frequent respiratory exposure to PM2.5 in rats

inferredcites →https://doi.org/10.1039/c3cs35405aopenalex-snapshot

Synthesis of mesoporous silica nanoparticles

inferredcites →https://doi.org/10.1097/ede.0b013e31824cbd6dopenalex-snapshot

Ambient Particulate Matter and Lung Function Growth in Chinese Children

inferredcites →https://doi.org/10.1126/science.1108752openalex-snapshot

Air Pollution-Related Illness: Effects of Particles

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Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis

inferredcites →https://doi.org/10.1136/oemed-2014-102303openalex-snapshot

Associations between three specific a-cellular measures of the oxidative potential of particulate matter and markers of acute airway and nasal inflammation in healthy volunteers

inferredcites →https://doi.org/10.1152/ajpcell.00529.2009openalex-snapshot

Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues

inferredcites →https://doi.org/10.1152/ajplung.00287.2014openalex-snapshot

Airway epithelial cell PPARγ modulates cigarette smoke-induced chemokine expression and emphysema susceptibility in mice

inferredcites →https://doi.org/10.1155/2013/354087openalex-snapshot

Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1

inferredcites →https://doi.org/10.1155/2015/729017openalex-snapshot

Polydatin Inhibits Formation of Macrophage-Derived Foam Cells

inferredcites →https://doi.org/10.1155/2016/9394150openalex-snapshot

Polydatin Protects Bone Marrow Stem Cells against Oxidative Injury: Involvement of Nrf 2/ARE Pathways

inferredcites →https://doi.org/10.1164/rccm.201308-1414ocopenalex-snapshot

Short-Term Exposure to Air Pollution and Lung Function in the Framingham Heart Study

inferredcites →https://doi.org/10.1164/rccm.201410-1875ocopenalex-snapshot

Long-Term Exposure to Traffic Emissions and Fine Particulate Matter and Lung Function Decline in the Framingham Heart Study

inferredcites →https://doi.org/10.1165/rcmb.2010-0220rtopenalex-snapshot

Lung Injury and Cancer

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Combustion-derived flame generated ultrafine soot generates reactive oxygen species and activates Nrf2 antioxidants differently in neonatal and adult rat lungs

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Carbon nanoparticles induce ceramide- and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally-induced lung inflammation

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Ambient PM2.5 and risk of emergency room visits for myocardial infarction: impact of regional PM2.5 oxidative potential: a case-crossover study

inferredcites →https://doi.org/10.1186/s12989-014-0073-1openalex-snapshot

Reduced pulmonary function and increased pro-inflammatory cytokines in nanoscale carbon black-exposed workers

inferredcites →https://doi.org/10.1186/s12989-015-0079-3openalex-snapshot

Translational toxicology in setting occupational exposure limits for dusts and hazard classification – a critical evaluation of a recent approach to translate dust overload findings from rats to humans

inferredcites →https://doi.org/10.1289/ehp.001081063openalex-snapshot

Distribution of Particulate Matter and Tissue Remodeling in the Human Lung

inferredcites →https://doi.org/10.1289/ehp.0800319openalex-snapshot

The Adjuvant Effect of Ambient Particulate Matter Is Closely Reflected by the Particulate Oxidant Potential

inferredcites →https://doi.org/10.1371/journal.pone.0052454openalex-snapshot

Sphingolipids as New Biomarkers for Assessment of Delayed-Type Hypersensitivity and Response to Triptolide

inferredcites →https://doi.org/10.3109/08958378.2011.632787openalex-snapshot

Regional particle size dependent deposition of inhaled aerosols in rats and mice

inferredcites →https://doi.org/10.3389/fphys.2015.00294openalex-snapshot

Fine particulate matter in acute exacerbation of COPD

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Short-Term Effects of Fine Particulate Matter and Temperature on Lung Function among Healthy College Students in Wuhan, China

inferredcites →https://doi.org/10.4049/jimmunol.1101380openalex-snapshot

Suppression of the NF-κB Pathway by Diesel Exhaust Particles Impairs Human Antimycobacterial Immunity

inferredcites →https://doi.org/10.4049/jimmunol.173.5.3467openalex-snapshot

Nrf2 Is a Key Transcription Factor That Regulates Antioxidant Defense in Macrophages and Epithelial Cells: Protecting against the Proinflammatory and Oxidizing Effects of Diesel Exhaust Chemicals

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4046779openalex-extracted

Radiation Protection Effect of Polydatin on Radon Exposure Injury of Epithelial Cells and Miceradiation Protection Effect of Polydatin on Radon Exposure Injury of Epithelial Cells and Mice

inferred← citeshttps://doi.org/10.1002/cbin.70145openalex-snapshot

Polydatin as a Multifunctional Anticancer Agent: Cellular Mechanisms, Therapeutic Potential and Future Clinical Perspectives

inferred← citeshttps://doi.org/10.1002/ptr.7306openalex-snapshot

Old dog, new tricks: Polydatin as a multitarget agent for current diseases

inferred← citeshttps://doi.org/10.1002/smll.202000845openalex-snapshot

Ovarian Dysfunction Induced by Chronic Whole‐Body PM2.5 Exposure

inferred← citeshttps://doi.org/10.1007/978-3-030-72385-9_5openalex-snapshot

Ventilative Cooling and Air Pollutants

inferred← citeshttps://doi.org/10.1007/s11101-018-9574-0openalex-snapshot

Recent advances in chemistry, therapeutic properties and sources of polydatin

inferred← citeshttps://doi.org/10.1007/s12038-019-9858-6openalex-snapshot

PM2.5 affects establishment of immune tolerance in newborn mice by reducing PD-L1 expression

inferred← citeshttps://doi.org/10.1007/s12257-022-0286-3openalex-snapshot

The Inhibitory Functions of Sparstolonin B against Ambient Fine Particulate Matter Induced Lung Injury

inferred← citeshttps://doi.org/10.1007/s13659-020-00271-zopenalex-snapshot

The upshot of Polyphenolic compounds on immunity amid COVID-19 pandemic and other emerging communicable diseases: An appraisal

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2017.05.152openalex-snapshot

Inhibition of miR-32 activity promoted EMT induced by PM2.5 exposure through the modulation of the Smad1-mediated signaling pathways in lung cancer cells

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2019.03.028openalex-snapshot

The effects of cooking oil fumes-derived PM2.5 on blood vessel formation through ROS-mediated NLRP3 inflammasome pathway in human umbilical vein endothelial cells

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2020.110878openalex-snapshot

Amelioration of PM2.5-induced lung toxicity in rats by nutritional supplementation with biochanin A

inferred← citeshttps://doi.org/10.1016/j.envres.2020.109230openalex-snapshot

Inhibitory functions of maslinic acid on particulate matter-induced lung injury through TLR4-mTOR-autophagy pathways

inferred← citeshttps://doi.org/10.1016/j.fitote.2020.104724openalex-snapshot

Inhibitory functions of cardamonin against particulate matter-induced lung injury through TLR2,4-mTOR-autophagy pathways

inferred← citeshttps://doi.org/10.1016/j.jep.2019.112126openalex-snapshot

An animal research and a chemical composition analysis of a Chinese prescription for pulmonary fibrosis: Yangfei Huoxue Decoction

inferred← citeshttps://doi.org/10.1016/j.jpha.2025.101451openalex-snapshot

Polydatin for treating spinal cord injury: Multiple mechanisms and challenges

inferred← citeshttps://doi.org/10.1016/j.phymed.2021.153912openalex-snapshot

Astragaloside IV pre-treatment attenuates PM2.5-induced lung injury in rats: Impact on autophagy, apoptosis and inflammation

inferred← citeshttps://doi.org/10.1016/j.scs.2018.07.011openalex-snapshot

Impact of PM2.5 in indoor urban environments: A review

inferred← citeshttps://doi.org/10.1016/j.taap.2019.01.013openalex-snapshot

Protective effects of polydatin against sulfur mustard-induced hepatic injury

inferred← citeshttps://doi.org/10.1016/s1875-5364(18)30054-2openalex-snapshot

Label-free quantitative proteomics reveals fibrinopeptide B and heparin cofactor II as potential serum biomarkers in respiratory syncytial virus-infected mice treated with Qingfei oral liquid formula

inferred← citeshttps://doi.org/10.1021/acsbiomaterials.0c00221openalex-snapshot

Assessment of Air Pollutant PM2.5 Pulmonary Exposure Using a 3D Lung-on-Chip Model

inferred← citeshttps://doi.org/10.1038/s41598-019-47872-4openalex-snapshot

Kefir peptides alleviate particulate matter <4 μm (PM4.0)-induced pulmonary inflammation by inhibiting the NF-κB pathway using luciferase transgenic mice

inferred← citeshttps://doi.org/10.1039/c9fo01382bopenalex-snapshot

Biochanin A protects against PM 2.5 -induced acute pulmonary cell injury by interacting with the target protein MEK5

inferred← citeshttps://doi.org/10.1080/09603123.2019.1652252openalex-snapshot

Inhibitory effects of cudratricusxanthone O on particulate matter-induced pulmonary injury

inferred← citeshttps://doi.org/10.1080/09603123.2022.2102156openalex-snapshot

Jujuboside B post-treatment attenuates PM 2.5 -induced lung injury in mice

inferred← citeshttps://doi.org/10.1080/15287394.2019.1646174openalex-snapshot

Inhibitory effects of compounds isolated from Dioscorea batatas Decne peel on particulate matter-induced pulmonary injury in mice

inferred← citeshttps://doi.org/10.1097/md.0000000000036918openalex-snapshot

Preliminary study on molecular mechanism of COVID-19 intervention by Polygonum cuspidatum through computer bioinformatics

inferred← citeshttps://doi.org/10.1109/tgrs.2021.3064191openalex-snapshot

Ultrahigh-Resolution (250 m) Regional Surface PM2.5 Concentrations Derived First From MODIS Measurements

inferred← citeshttps://doi.org/10.1111/jcmm.13848openalex-snapshot

Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats

inferred← citeshttps://doi.org/10.1111/jcmm.17937openalex-snapshot

Polydatin alleviates bleomycin‐induced pulmonary fibrosis and alters the gut microbiota in a mouse model

inferred← citeshttps://doi.org/10.1155/2022/4714914openalex-snapshot

Impact of Phytochemicals on PPAR Receptors: Implications for Disease Treatments

inferred← citeshttps://doi.org/10.11606/t.5.2023.tde-18092023-162400openalex-snapshot

Efeitos do resveratrol no pulmão de camundongos idosos expostos à exaustão do motor a diesel

inferred← citeshttps://doi.org/10.1177/15593258231172271openalex-snapshot

Radiation Protection of Polydatin Against Radon Exposure Injury of Epithelial Cells and Mice

inferred← citeshttps://doi.org/10.14218/fim.2022.00030openalex-snapshot

Interventional Effects of Grape Skin Extract against Lung Injury Induced by Artificial Fine Particulate Matter in a Rat Model

inferred← citeshttps://doi.org/10.26554/ijems.2020.4.3.85-89openalex-snapshot

Effects of Spirulina platensis extract on serum Malondialdehyde (MDA) levels and differential leukocyte count on motor vehicle exhaust emissions exposure (in vivo study on Wistar rats)

inferred← citeshttps://doi.org/10.3389/fphar.2026.1752467openalex-snapshot

Polydatin in respiratory diseases: multi-target mechanisms and therapeutic potential

inferred← citeshttps://doi.org/10.3390/biom11071048openalex-snapshot

Interference of Polydatin/Resveratrol in the ACE2:Spike Recognition during COVID-19 Infection. A Focus on Their Potential Mechanism of Action through Computational and Biochemical Assays

inferred← citeshttps://doi.org/10.3390/ijms20010055openalex-snapshot

Protective Effect of Colla corii asini against Lung Injuries Induced by Intratracheal Instillation of Artificial Fine Particles in Rats

inferred← citeshttps://doi.org/10.3390/ijms21041462openalex-snapshot

Biapenem as a Novel Insight into Drug Repositioning against Particulate Matter-Induced Lung Injury

inferred← citeshttps://doi.org/10.3390/ijms232213948openalex-snapshot

Cirsilineol Treatment Attenuates PM2.5-Induced Lung Injury in Mice

inferred← citeshttps://doi.org/10.3390/ijms24054979openalex-snapshot

Therapeutic Effects of Cornuside on Particulate Matter–Induced Lung Injury

inferred← citeshttps://doi.org/10.3390/math10162878openalex-snapshot

Bayesian Aerosol Retrieval-Based PM2.5 Estimation through Hierarchical Gaussian Process Models

inferred← citeshttps://doi.org/10.3390/nu11112792openalex-snapshot

Polydatin Inhibits NLRP3 Inflammasome in Dry Eye Disease by Attenuating Oxidative Stress and Inhibiting the NF-κB Pathway

inferred← citeshttps://doi.org/10.3390/toxics13040236openalex-snapshot

Synergistic Toxicity of Fine Particulate Matter and Ozone and Their Underlying Mechanisms

inferred← citeshttps://doi.org/10.3892/etm.2020.9190openalex-snapshot

Polydatin prevents bleomycin‑induced pulmonary fibrosis by inhibiting the TGF‑β/Smad/ERK signaling pathway

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