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Domain-specific interactions between MLN8237 and human serum albumin estimated by STD and WaterLOGSY NMR, ITC, spectroscopic, and docking techniques

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cbic.201300613openalex-snapshot
Long Residence Times Revealed by Aurora A Kinase‐Targeting Fluorescent Probes Derived from Inhibitors MLN8237 and VX‐689
inferredcites →https://doi.org/10.1002/cncr.23371openalex-snapshot
Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions
inferredcites →https://doi.org/10.1007/s40268-015-0114-8openalex-snapshot
Effect of Food on the Pharmacokinetics of the Investigational Aurora A Kinase Inhibitor Alisertib (MLN8237) in Patients with Advanced Solid Tumors
inferredcites →https://doi.org/10.1016/j.abb.2016.07.016openalex-snapshot
Interaction of lafutidine in binding to human serum albumin in gastric ulcer therapy: STD-NMR, WaterLOGSY-NMR, NMR relaxation times, Tr-NOESY, molecule docking, and spectroscopic studies
inferredcites →https://doi.org/10.1016/j.bcp.2011.01.017openalex-snapshot
Aurora inhibitor MLN8237 in combination with docetaxel enhances apoptosis and anti-tumor activity in mantle cell lymphoma
inferredcites →https://doi.org/10.1016/j.bioorg.2016.04.002openalex-snapshot
Binding mechanism of trans-N-caffeoyltyramine and human serum albumin: Investigation by multi-spectroscopy and docking simulation
inferredcites →https://doi.org/10.1016/j.bmc.2010.08.052openalex-snapshot
A combined spectroscopic and crystallographic approach to probing drug–human serum albumin interactions
inferredcites →https://doi.org/10.1016/j.colsurfb.2014.09.044openalex-snapshot
Interaction of 5-fluoro-5′-deoxyuridine with human serum albumin under physiological and non-physiological condition: A biophysical investigation
inferredcites →https://doi.org/10.1016/j.ejmech.2015.02.025openalex-snapshot
Comparison between loureirin A and cochinchinenin C on the interaction with human serum albumin
inferredcites →https://doi.org/10.1016/j.foodchem.2015.01.133openalex-snapshot
β-Carotene and astaxanthin with human and bovine serum albumins
inferredcites →https://doi.org/10.1016/j.ica.2014.03.002openalex-snapshot
DNA/protein interaction and cytotoxicity of palladium(II) complexes of thiocarboxamide ligands
inferredcites →https://doi.org/10.1016/j.ijbiomac.2015.03.052openalex-snapshot
Spectroscopy study and co-administration effect on the interaction of mycophenolic acid and human serum albumin
inferredcites →https://doi.org/10.1016/j.jlumin.2015.07.016openalex-snapshot
Biophysical study on the interaction between two palladium(II) complexes and human serum albumin by Multispectroscopic methods
inferredcites →https://doi.org/10.1016/j.jmb.2005.07.075openalex-snapshot
Structural Basis of the Drug-binding Specificity of Human Serum Albumin
inferredcites →https://doi.org/10.1016/j.jpba.2013.01.002openalex-snapshot
Alkyl chain dependent interactions of ligands with bovine serum albumin
inferredcites →https://doi.org/10.1016/j.jphotobiol.2016.02.009openalex-snapshot
Interplay of multiple interaction forces: Binding of tyrosine kinase inhibitor nintedanib with human serum albumin
inferredcites →https://doi.org/10.1016/j.jsb.2006.08.015openalex-snapshot
Effect of human serum albumin on drug metabolism: Structural evidence of esterase activity of human serum albumin
inferredcites →https://doi.org/10.1016/j.jsb.2010.10.004openalex-snapshot
Structural basis of binding of fluorescent, site-specific dansylated amino acids to human serum albumin
inferredcites →https://doi.org/10.1016/j.molstruc.2014.11.020openalex-snapshot
Probing the binding of procyanidin B3 to human serum albumin by isothermal titration calorimetry
inferredcites →https://doi.org/10.1016/j.saa.2015.07.051openalex-snapshot
Caffeine and sulfadiazine interact differently with human serum albumin: A combined fluorescence and molecular docking study
inferredcites →https://doi.org/10.1016/j.saa.2016.02.015openalex-snapshot
Exploring the interaction between Salvia miltiorrhiza and human serum albumin: Insights from herb–drug interaction reports, computational analysis and experimental studies
inferredcites →https://doi.org/10.1016/j.talanta.2014.06.060openalex-snapshot
Molecular interactions between some non-steroidal anti-inflammatory drugs (NSAID׳s) and bovine (BSA) or human (HSA) serum albumin estimated by means of isothermal titration calorimetry (ITC) and frontal analysis capillary electrophoresis (FA/CE)
inferredcites →https://doi.org/10.1016/s0015-7368(71)70633-1openalex-snapshot
The Nature and Evidential Value of the Luminescence of Automobile Engine Oils and Related Materials
inferredcites →https://doi.org/10.1016/s0065-3233(08)60640-3openalex-snapshot
Structure of Serum Albumin
inferredcites →https://doi.org/10.1021/bi00514a017openalex-snapshot
Thermodynamics of protein association reactions: forces contributing to stability
inferredcites →https://doi.org/10.1021/ja990706xopenalex-snapshot
Detecting Binding Affinity to Immobilized Receptor Proteins in Compound Libraries by HR-MAS STD NMR
inferredcites →https://doi.org/10.1038/physci231064a0openalex-snapshot
Synchronized Excitation of Fluorescence Emission Spectra
inferredcites →https://doi.org/10.1039/an9840900191openalex-snapshot
Recent developments in fluorescence and chemiluminescence analysis. Plenary lecture
inferredcites →https://doi.org/10.1039/b919952gopenalex-snapshot
A multitechnique study of europium decatungstate and human serum albumin molecular interaction
inferredcites →https://doi.org/10.1039/c4cp03534hopenalex-snapshot
Epitope mapping of imidazolium cations in ionic liquid–protein interactions unveils the balance between hydrophobicity and electrostatics towards protein destabilisation
inferredcites →https://doi.org/10.1039/c4cp05734aopenalex-snapshot
Interaction of different prototropic species of an anticancer drug ellipticine with HSA and IgG proteins: multispectroscopic and molecular modeling studies
inferredcites →https://doi.org/10.1039/c5md00231aopenalex-snapshot
Evaluation of binding competition and group epitopes of acetylcholinesterase inhibitors by STD NMR, Tr-NOESY, DOSY and molecular docking: an old approach but new findings
inferredcites →https://doi.org/10.1039/c5nj01902hopenalex-snapshot
Supramolecular catalysis by β-cyclodextrin for the synthesis of kojic acid derivatives in water
inferredcites →https://doi.org/10.1039/c5nj02003dopenalex-snapshot
In vitro investigation of the interaction between the hepatitis C virus drug sofosbuvir and human serum albumin through 1 H NMR, molecular docking, and spectroscopic analyses
inferredcites →https://doi.org/10.1039/c5ra01457copenalex-snapshot
Human serum albumin-specific recognition of the natural herbal extract of Stryphnodendron polyphyllum through STD NMR, hyphenations and docking simulation studies
inferredcites →https://doi.org/10.1080/07391102.2015.1075905openalex-snapshot
Insights into the binding of thiosemicarbazone derivatives with human serum albumin: spectroscopy and molecular modelling studies
inferredcites →https://doi.org/10.1111/j.1582-4934.2010.01218.xopenalex-snapshot
The novel Aurora A kinase inhibitor MLN8237 is active in resistant chronic myeloid leukaemia and significantly increases the efficacy of nilotinib
inferredcites →https://doi.org/10.1158/1078-0432.ccr-12-0571openalex-snapshot
Phase I Pharmacokinetic/Pharmacodynamic Study of MLN8237, an Investigational, Oral, Selective Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
inferredcites →https://doi.org/10.1158/1078-0432.ccr-12-0589openalex-snapshot
Phase I Study of Aurora A Kinase Inhibitor MLN8237 in Advanced Solid Tumors: Safety, Pharmacokinetics, Pharmacodynamics, and Bioavailability of Two Oral Formulations
inferredcites →https://doi.org/10.1186/1479-5876-9-100openalex-snapshot
Aurora Kinase A expression is associated with lung cancer histological-subtypes and with tumor de-differentiation
inferredcites →https://doi.org/10.15171/apb.2016.031openalex-snapshot
Interactions Between Sirolimus and Anti-Inflammatory Drugs: Competitive Binding for Human Serum Albumin
inferredcites →https://doi.org/10.2147/dddt.s74197openalex-snapshot
Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway
inferredcites →https://doi.org/10.2174/1872312807666131229122359openalex-snapshot
Preclinical Drug Metabolism and Pharmacokinetics, and Prediction of Human Pharmacokinetics and Efficacious Dose of the Investigational Aurora A Kinase Inhibitor Alisertib (MLN8237)

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1002/mrc.70052openalex-snapshot
Solvent‐Based NMR Approaches for the Assessment of Molecular Interactions: A Review of Current Practices
inferred← citeshttps://doi.org/10.1007/s00216-021-03700-1openalex-snapshot
Lysine reactivity profiling reveals molecular insights into human serum albumin–small-molecule drug interactions
inferred← citeshttps://doi.org/10.1016/bs.mie.2018.08.020openalex-snapshot
Protein–Small Molecule Interactions by WaterLOGSY
inferred← citeshttps://doi.org/10.1016/j.abb.2018.06.005openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.abb.2019.108123openalex-snapshot
Warfarin increases thermal resistance of albumin through stabilization of the protein lobe that includes its binding site
inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.01.064openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.foodchem.2018.02.105openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.molstruc.2023.136694openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.molstruc.2023.136737openalex-snapshot
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inferred← citeshttps://doi.org/10.1039/c7ra12890hopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/c8nj05486jopenalex-snapshot
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inferred← citeshttps://doi.org/10.1080/07391102.2018.1449667openalex-snapshot
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Elucidating the molecular interaction of serum albumin with nizatidine and the role of β-cyclodextrin: multi-spectroscopic and computational approach
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Interaction of Mitoxantrone-Loaded Cholesterol Modified Pullulan Nanoparticles with Human Serum Albumin and Effect on Drug Release
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