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Genetic effects influencing risk for major depressive disorder in China and Europe

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/gepi.20630openalex-snapshot
Transethnic meta‐analysis of genomewide association studies
inferredcites →https://doi.org/10.1016/j.ajhg.2013.07.007openalex-snapshot
Additive Genetic Variation in Schizophrenia Risk Is Shared by Populations of African and European Descent
inferredcites →https://doi.org/10.1016/j.ajhg.2016.05.001openalex-snapshot
Transethnic Genetic-Correlation Estimates from Summary Statistics
inferredcites →https://doi.org/10.1016/j.biopsych.2010.07.010openalex-snapshot
Genome-Wide Association Study of Schizophrenia in a Japanese Population
inferredcites →https://doi.org/10.1016/j.biopsych.2012.09.033openalex-snapshot
A Genome-Wide Association Study of Depressive Symptoms
inferredcites →https://doi.org/10.1016/j.biopsych.2016.05.010openalex-snapshot
Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
inferredcites →https://doi.org/10.1016/j.neuron.2014.01.027openalex-snapshot
The Genetics of Major Depression
inferredcites →https://doi.org/10.1038/mp.2010.109openalex-snapshot
Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned
inferredcites →https://doi.org/10.1038/mp.2011.94openalex-snapshot
Don't give up on GWAS
inferredcites →https://doi.org/10.1038/mp.2012.21openalex-snapshot
A mega-analysis of genome-wide association studies for major depressive disorder
inferredcites →https://doi.org/10.1038/mp.2014.107openalex-snapshot
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption
inferredcites →https://doi.org/10.1038/nature04226openalex-snapshot
A haplotype map of the human genome
inferredcites →https://doi.org/10.1038/nature08185openalex-snapshot
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
inferredcites →https://doi.org/10.1038/nature11632openalex-snapshot
An integrated map of genetic variation from 1,092 human genomes
inferredcites →https://doi.org/10.1038/nature13595openalex-snapshot
Biological insights from 108 schizophrenia-associated genetic loci
inferredcites →https://doi.org/10.1038/nature14659openalex-snapshot
Sparse whole-genome sequencing identifies two loci for major depressive disorder
inferredcites →https://doi.org/10.1038/ncomms5613openalex-snapshot
Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A
inferredcites →https://doi.org/10.1038/ncomms6890openalex-snapshot
Biological interpretation of genome-wide association studies using predicted gene functions
inferredcites →https://doi.org/10.1038/ncomms7534openalex-snapshot
Human gephyrin is encompassed within giant functional noncoding yin–yang sequences
inferredcites →https://doi.org/10.1038/ncomms7916openalex-snapshot
Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility
inferredcites →https://doi.org/10.1038/ng.2897openalex-snapshot
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
inferredcites →https://doi.org/10.1038/ng.3173openalex-snapshot
Gene expression analysis identifies global gene dosage sensitivity in cancer
inferredcites →https://doi.org/10.1038/ng.3424openalex-snapshot
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
inferredcites →https://doi.org/10.1038/ng.3623openalex-snapshot
Identification of 15 genetic loci associated with risk of major depression in individuals of European descent
inferredcites →https://doi.org/10.1038/ng1474openalex-snapshot
'Racial' differences in genetic effects for complex diseases
inferredcites →https://doi.org/10.1038/nrn3670openalex-snapshot
Gephyrin: a master regulator of neuronal function?
inferredcites →https://doi.org/10.1086/519795openalex-snapshot
PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses
inferredcites →https://doi.org/10.1093/hmg/10.10.1077openalex-snapshot
Trans-ethnic fine mapping of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE)
inferredcites →https://doi.org/10.1093/hmg/ddu183openalex-snapshot
Multi-ethnic fine-mapping of 14 central adiposity loci
inferredcites →https://doi.org/10.1093/hmg/ddu401openalex-snapshot
Trans-ethnic meta-analysis of white blood cell phenotypes
inferredcites →https://doi.org/10.1097/ede.0000000000000168openalex-snapshot
Evidence of Heterogeneity by Race/Ethnicity in Genetic Determinants of QT Interval
inferredcites →https://doi.org/10.1111/j.1600-0047.2004.00329.xopenalex-snapshot
Disability and quality of life impact of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project
inferredcites →https://doi.org/10.1159/000444713openalex-snapshot
Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy
inferredcites →https://doi.org/10.1176/appi.ajp.157.10.1552openalex-snapshot
Genetic Epidemiology of Major Depression: Review and Meta-Analysis
inferredcites →https://doi.org/10.1192/bjp.184.5.386openalex-snapshot
Global burden of depressive disorders in the year 2000
inferredcites →https://doi.org/10.1371/journal.pgen.1000529openalex-snapshot
A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies
inferredcites →https://doi.org/10.1371/journal.pgen.1003379openalex-snapshot
Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained
inferredcites →https://doi.org/10.1371/journal.pgen.1004517openalex-snapshot
Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes
inferredcites →https://doi.org/10.1371/journal.pone.0086449openalex-snapshot
New Susceptibility and Resistance HLA-DP Alleles to HBV-Related Diseases Identified by a Trans-Ethnic Association Study in Asia

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Genetic Architecture of Bipolar Disorder in Individuals of Han Chinese and European Ancestries
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The Genetic Architecture of Depression in Individuals of East Asian Ancestry
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Major Depressive Disorder and Depressive Symptoms
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Evaluating marginal genetic correlation of associated loci for complex diseases and traits between European and East Asian populations
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Serotonin in psychiatry: in vitro disease modeling using patient-derived neurons
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Polygenic Scores for ADHD: A Meta-Analysis
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Genetics of Depression: Progress at Last
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Genomic Basis of Psychiatric Illnesses and Response to Psychiatric Drug Treatment Modalities
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Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations
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Genetic evidence of increased schizophrenia risk due to antidepressant use in European and East Asian populations
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Genome-wide copy number variation-, validation- and screening study implicates a new copy number polymorphism associated with suicide attempts in major depressive disorder
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Do depressive symptoms predict cognitive function decline in middle-aged and older adults? A three-wave longitudinal study
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Genome-wide association study of depressive symptoms in the Hispanic Community Health Study/Study of Latinos
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Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders
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Depression
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Mood Disorders in Prader-Willi Syndrome
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Gene–environment interactions between HPA-axis genes and stressful life events in depression: a systematic review
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Polygenic risk for severe psychopathology among Europeans is associated with major depressive disorder in Han Chinese women
inferred← citeshttps://doi.org/10.1017/s0033291718003641openalex-snapshot
Translating GWAS findings into therapies for depression and anxiety disorders: gene-set analyses reveal enrichment of psychiatric drug classes and implications for drug repositioning
inferred← citeshttps://doi.org/10.1017/s0033291721000441openalex-snapshot
The genetic basis of major depression
inferred← citeshttps://doi.org/10.1017/s003329172610498xopenalex-snapshot
Peripheral transcriptomic aging acceleration in major depressive disorder: the mediating role of insular cortex alterations
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Validating psychosocial pathways of risk between neuroticism and late life depression using a polygenic score approach.
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The Gene Encoding Protocadherin 9 (PCDH9), a Novel Risk Factor for Major Depressive Disorder
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CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research
inferred← citeshttps://doi.org/10.1038/s41380-020-0689-5openalex-snapshot
Association of polygenic score for major depression with response to lithium in patients with bipolar disorder
inferred← citeshttps://doi.org/10.1038/s41386-018-0078-9openalex-snapshot
Common variants on 6q16.2, 12q24.31 and 16p13.3 are associated with major depressive disorder
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Integrative analyses of major histocompatibility complex loci in the genome-wide association studies of major depressive disorder
inferred← citeshttps://doi.org/10.1038/s41398-020-0777-yopenalex-snapshot
Further confirmation of netrin 1 receptor (DCC) as a depression risk gene via integrations of multi-omics data
inferred← citeshttps://doi.org/10.1038/s41398-021-01522-4openalex-snapshot
Phenotypic and genetic associations between anhedonia and brain structure in UK Biobank
inferred← citeshttps://doi.org/10.1038/s41398-022-02074-xopenalex-snapshot
Multivariate genome-wide association study of depression, cognition, and memory phenotypes and validation analysis identify 12 cross-ethnic variants
inferred← citeshttps://doi.org/10.1038/s41398-024-02959-zopenalex-snapshot
Inflammation and immune system pathways as biological signatures of adolescent depression—the IDEA-RiSCo study
inferred← citeshttps://doi.org/10.1038/s41588-018-0090-3openalex-snapshot
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
inferred← citeshttps://doi.org/10.1038/s41588-023-01596-4openalex-snapshot
Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference
inferred← citeshttps://doi.org/10.1038/s41598-021-84739-zopenalex-snapshot
Quantifying genetic heterogeneity between continental populations for human height and body mass index
inferred← citeshttps://doi.org/10.1038/s43586-022-00191-xopenalex-snapshot
Behavioural genetics methods
inferred← citeshttps://doi.org/10.1038/s44220-026-00667-9openalex-snapshot
Vertex-wise cortical abnormalities in major depressive disorder from 64 cohorts from the DIRECT and ENIGMA MDD consortia
inferred← citeshttps://doi.org/10.1093/cercor/bhad002openalex-snapshot
Global diversity in individualized cortical network topography
inferred← citeshttps://doi.org/10.1093/hmg/ddaa115openalex-snapshot
Reviewing the genetics of heterogeneity in depression: operationalizations, manifestations and etiologies
inferred← citeshttps://doi.org/10.1093/hmg/ddaa192openalex-snapshot
Implicit bias of encoded variables: frameworks for addressing structured bias in EHR–GWAS data
inferred← citeshttps://doi.org/10.1093/psyrad/kkac005openalex-snapshot
The DIRECT consortium and the REST-meta-MDD project: towards neuroimaging biomarkers of major depressive disorder
inferred← citeshttps://doi.org/10.1093/schbul/sby140openalex-snapshot
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect
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Body size reference norms and subjective weight status: A gender and life course approach
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Elucidating the Joint Genetic Architecture of Mood Disorder and Schizophrenia
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Phenotype Risk Scores: moving beyond ‘cases’ and ‘controls’ to classify psychiatric disease in hospital-based biobanks
inferred← citeshttps://doi.org/10.1101/2021.06.30.21259731openalex-snapshot
DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses
inferred← citeshttps://doi.org/10.1101/2022.07.20.500802openalex-snapshot
Multi-ancestry GWAS of major depression aids locus discovery, fine-mapping, gene prioritisation, and causal inference
inferred← citeshttps://doi.org/10.1101/2025.02.22.25322721openalex-snapshot
Trans-ancestry Genome-Wide Analyses in UK Biobank Yield Novel Risk Loci for Major Depression
inferred← citeshttps://doi.org/10.1101/2025.05.09.653064openalex-snapshot
Lifestyle, Early-life, and Genetic Health Risk Factors Underlying the Brain Age Gap: A Mega-Analysis Across 3,934 Individuals from the ENIGMA MDD Consortium
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Polygenic risk for depression, anxiety and neuroticism are associated with the severity and rate of change in depressive symptoms across adolescence
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Polygenic Risk Scores in Clinical Psychology: Bridging Genomic Risk to Individual Differences
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VRK2, a Candidate Gene for Psychiatric and Neurological Disorders
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Efeito de poliformismos genéticos do gene HSD11b1 sobre o risco para desenvolver depressão na população brasileira
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Efeitos do exercício físico aeróbico com e sem complexidade motora na desesperança, percepção afetiva e na volumetria da amígdala, tálamo e do núcleo accumbens em indivíduos com depressão maior do Sistema Único de Saúde
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Molecular Genetic Analysis Subdivided by Adversity Exposure Suggests Etiologic Heterogeneity in Major Depression
inferred← citeshttps://doi.org/10.1186/s12864-023-09425-yopenalex-snapshot
Evaluating significance of European-associated index SNPs in the East Asian population for 31 complex phenotypes
inferred← citeshttps://doi.org/10.1186/s12864-023-09434-xopenalex-snapshot
Similarity and diversity of genetic architecture for complex traits between East Asian and European populations
inferred← citeshttps://doi.org/10.1186/s12888-020-02798-4openalex-snapshot
Influence of genetic polymorphisms in homocysteine and lipid metabolism systems on antidepressant drug response
inferred← citeshttps://doi.org/10.1186/s12967-022-03637-8openalex-snapshot
Detecting associated genes for complex traits shared across East Asian and European populations under the framework of composite null hypothesis testing
inferred← citeshttps://doi.org/10.1186/s12967-024-05053-6openalex-snapshot
Incorporating genetic similarity of auxiliary samples into eGene identification under the transfer learning framework
inferred← citeshttps://doi.org/10.1186/s12993-025-00309-7openalex-snapshot
Overexpression of Hspa1b in the mouse hippocampus may be associated with major depressive disorder
inferred← citeshttps://doi.org/10.1186/s13073-022-01039-5openalex-snapshot
DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses
inferred← citeshttps://doi.org/10.1186/s13148-019-0769-zopenalex-snapshot
DNA methylation associated with postpartum depressive symptoms overlaps findings from a genome-wide association meta-analysis of depression
inferred← citeshttps://doi.org/10.12677/acm.2022.125615openalex-snapshot
Research Status of Related Influencing Factors of Depressive Disorder
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On the utilization of polygenic risk scores for therapeutic targeting
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THE ROLE OF OXIDATIVE STRESS IN THE ETIOPATHOGENESIS OF DEPRESSION
inferred← citeshttps://doi.org/10.21203/rs.3.rs-6192393/v1openalex-snapshot
Overexpression of Hspa1b in the Mouse Hippocampus Is Associated with Major Depressive Disorder
inferred← citeshttps://doi.org/10.2217/pgs-2020-0157openalex-snapshot
Therapy Response Prediction in Major Depressive Disorder: Current and Novel Genomic Markers Influencing Pharmacokinetics and Pharmacodynamics
inferred← citeshttps://doi.org/10.25557/2073-7998.2021.06.27-32openalex-snapshot
Structural features of the gene SIRT1 in residents of the Siberian region
inferred← citeshttps://doi.org/10.3389/fpsyt.2018.00334openalex-snapshot
Genetics Factors in Major Depression Disease
inferred← citeshttps://doi.org/10.3389/fpsyt.2021.705998openalex-snapshot
Common and Distinct Alterations of Cognitive Function and Brain Structure in Schizophrenia and Major Depressive Disorder: A Pilot Study
inferred← citeshttps://doi.org/10.3389/frai.2026.1823559openalex-snapshot
MCEEGNet: a multi-cue EEG network for quantitative assessment of depression using emotional stimuli-induced EEG signals
inferred← citeshttps://doi.org/10.3390/ijerph17124457openalex-snapshot
Positive Youth Development and Adolescent Depression: A Longitudinal Study Based on Mainland Chinese High School Students
inferred← citeshttps://doi.org/10.3390/nu9070659openalex-snapshot
Does Vitamin C Influence Neurodegenerative Diseases and Psychiatric Disorders?
inferred← citeshttps://doi.org/10.3758/s13428-023-02103-7openalex-snapshot
Real-time detection of mean and variance changes in experience sampling data: A comparison of existing and novel statistical process control approaches
inferred← citeshttps://doi.org/10.3928/00485713-20210315-01openalex-snapshot
The Genetics of Major Depression: Perspectives on the State of Research and Opportunities for Precision Medicine
inferred← citeshttps://doi.org/10.6035/14109.2020.261277openalex-snapshot
Eficacia de una intervención psicológica breve basada en mindfulness para el tratamiento de la depresión en atención primaria: aplicación cara a cara, aplicación mediante TICs versus tratamiento habitual
inferred← citeshttps://doi.org/10.6084/m9.figshare.21192253openalex-snapshot
Additional file 1 of Detecting associated genes for complex traits shared across East Asian and European populations under the framework of composite null hypothesis testing
inferred← citeshttps://doi.org/10.6084/m9.figshare.23505076openalex-snapshot
Additional file 1 of Similarity and diversity of genetic architecture for complex traits between East Asian and European populations
inferred← citeshttps://doi.org/10.6084/m9.figshare.23505079openalex-snapshot
Additional file 2 of Similarity and diversity of genetic architecture for complex traits between East Asian and European populations
inferred← citeshttps://doi.org/10.6084/m9.figshare.25376120openalex-snapshot
Additional file 1 of Incorporating genetic similarity of auxiliary samples into eGene identification under the transfer learning framework
inferred← citeshttps://doi.org/10.7551/mitpress/15380.003.0024openalex-snapshot
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