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Enzymatic resolution and evaluation of enantiomers of cis-5′-hydroxythalidomide
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/(sici)1099-0461(2000)14:3<140::aid-jbt3>3.0.co;2-popenalex-snapshot
Metabolism of thalidomide in human microsomes, cloned human cytochrome P-450 isozymes, and Hansen?s disease patients
inferredcites →https://doi.org/10.1002/(sici)1520-636x(1996)8:5<390::aid-chir6>3.0.co;2-iopenalex-snapshot
Enantioselective inhibition of TNF-? release by thalidomide and thalidomide-analogues
inferredcites →https://doi.org/10.1002/(sici)1520-636x(1998)10:3<223::aid-chir4>3.0.co;2-aopenalex-snapshot
Enantiomers of thalidomide: blood distribution and the influence of serum albumin on chiral inversion and hydrolysis
inferredcites →https://doi.org/10.1002/(sici)1521-4184(199801)331:1<7::aid-ardp7>3.0.co;2-nopenalex-snapshot
5′-Substituted Thalidomide Analogs as Modulators of TNF-α
inferredcites →https://doi.org/10.1002/1522-2683(20000901)21:15<3270::aid-elps3270>3.0.co;2-nopenalex-snapshot
Investigation of the stereoselective in vitro biotransformation of thalidomide using a dual cyclodextrin system in capillary electrophoresis
inferredcites →https://doi.org/10.1002/chir.530070109openalex-snapshot
Stereospecific determination, chiral inversion in vitro and pharmacokinetics in humans of the enantiomers of thalidomide
inferredcites →https://doi.org/10.1002/tcm.1770140303openalex-snapshot
Embryotoxic effects of thalidomide derivatives in the non‐human primate Callithrix jacchus. IV. Teratogenicity of μg/kg doses of the EM12 enantiomers
inferredcites →https://doi.org/10.1002/tera.1420380307openalex-snapshot
Proposed mechanisms of action in thalidomide embryopathy
inferredcites →https://doi.org/10.1006/exer.1997.0292openalex-snapshot
Effects of Thalidomide and Related Metabolites in a Mouse Corneal Model of Neovascularization
inferredcites →https://doi.org/10.1016/0021-9673(94)80385-4openalex-snapshot
Investigations on the in vitro racemization of thalidomide by high-performance liquid chromatography
inferredcites →https://doi.org/10.1016/0041-008x(86)90449-7openalex-snapshot
Teratogen metabolism: Thalidomide activation is mediated by cytochrome P-450
inferredcites →https://doi.org/10.1016/0140-6736(92)91685-2openalex-snapshot
Nifedipine and telangiectasias
inferredcites →https://doi.org/10.1016/0162-3109(95)00050-xopenalex-snapshot
Thalidomide selectively modulates the density of cell surface molecules involved in the adhesion cascade
inferredcites →https://doi.org/10.1016/0378-4347(95)00314-2openalex-snapshot
Investigation of the in vitro biotransformation and simultaneous enantioselective separation of thalidomide and its neutral metabolites by capillary electrophoresis
inferredcites →https://doi.org/10.1016/j.bmcl.2005.08.086openalex-snapshot
Angiogenesis inhibitors derived from thalidomide
inferredcites →https://doi.org/10.1016/j.exer.2006.11.007openalex-snapshot
New quantitative analysis, using high-resolution images, of oxygen-induced retinal neovascularization in mice
inferredcites →https://doi.org/10.1016/j.jpba.2007.06.010openalex-snapshot
Investigation of N-hydroxythalidomide in vitro stability and comparison to other N-substituted derivatives
inferredcites →https://doi.org/10.1016/j.tetasy.2004.09.019openalex-snapshot
Lipase-mediated chiral resolution of racemates in organic solvents
inferredcites →https://doi.org/10.1016/s0002-9440(10)64714-1openalex-snapshot
Thalidomide Inhibits Angiogenesis in Embryoid Bodies by the Generation of Hydroxyl Radicals
inferredcites →https://doi.org/10.1016/s0006-2952(98)00046-xopenalex-snapshot
Inhibition of Angiogenesis by Thalidomide Requires Metabolic Activation, Which Is Species-dependent
inferredcites →https://doi.org/10.1016/s0014-827x(02)01258-2openalex-snapshot
Recent results of biotransformation of drugs: investigation of the in vitro biotransformation of thalidomide using a dual cyclodextrin system in capillary electrophoresis
inferredcites →https://doi.org/10.1016/s0378-4347(98)00486-1openalex-snapshot
Investigation of the in vitro biotransformation of R-(+)-thalidomide by HPLC, nano-HPLC, CEC and HPLC–APCI-MS
inferredcites →https://doi.org/10.1016/s0968-0896(01)00308-xopenalex-snapshot
Structural development of biological response modifiers based on thalidomide
inferredcites →https://doi.org/10.1021/ac0203138openalex-snapshot
In Vitro Biotransformation of (R)-and (S)-Thalidomide: Application of Circular Dichroism Spectroscopy to the Stereochemical Characterization of the Hydroxylated Metabolites
inferredcites →https://doi.org/10.1021/jm0304820openalex-snapshot
Comparative Molecular Field Analysis and Comparative Molecular Similarity Indices Analysis of Thalidomide Analogues as Angiogenesis Inhibitors
inferredcites →https://doi.org/10.1021/jo0514772openalex-snapshot
Synthesis of Racemic cis-5-Hydroxy-3-phthalimidoglutarimide. A Metabolite of Thalidomide Isolated from Human Plasma
inferredcites →https://doi.org/10.1021/ol9902172openalex-snapshot
(R)- and (S)-3-Fluorothalidomides: Isosteric Analogues of Thalidomide
inferredcites →https://doi.org/10.1021/tx9801817openalex-snapshot
Chiral Inversion and Hydrolysis of Thalidomide: Mechanisms and Catalysis by Bases and Serum Albumin, and Chiral Stability of Teratogenic Metabolites
inferredcites →https://doi.org/10.1023/a:1021008016719openalex-snapshot
A Double-Blind Study of the Sedative Effects of the Thalidomide Enantiomers in Humans
inferredcites →https://doi.org/10.1038/8466openalex-snapshot
Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity
inferredcites →https://doi.org/10.1073/pnas.78.4.2545openalex-snapshot
Thalidomide teratogenesis: evidence for a toxic arene oxide metabolite.
inferredcites →https://doi.org/10.1073/pnas.91.9.4082openalex-snapshot
Thalidomide is an inhibitor of angiogenesis.
inferredcites →https://doi.org/10.1093/ecam/nem152openalex-snapshot
10‐Hydroxy‐2‐decenoic Acid, a Major Fatty Acid from Royal Jelly, Inhibits VEGF‐Induced Angiogenesis in Human Umbilical Vein Endothelial Cells
inferredcites →https://doi.org/10.1097/00007691-200202000-00017openalex-snapshot
5´-OH-Thalidomide, a Metabolite of Thalidomide, Inhibits Angiogenesis
inferredcites →https://doi.org/10.1111/j.2042-7158.1998.tb03368.xopenalex-snapshot
Hydroxylated Metabolites of Thalidomide: Formation In-vitro and In-vivo in Man
inferredcites →https://doi.org/10.1158/1078-0432.ccr-04-0421openalex-snapshot
Thalidomide Pharmacokinetics and Metabolite Formation in Mice, Rabbits, and Multiple Myeloma Patients
inferredcites →https://doi.org/10.1211/0022357001774660openalex-snapshot
Intravenous Formulations of the Enantiomers of Thalidomide: Pharmacokinetic and Initial Pharmacodynamic Characterization in Man
inferredcites →https://doi.org/10.1248/bpb.25.597openalex-snapshot
Effects of Putative Hydroxylated Thalidomide Metabolites on Blood Vessel Density in the Chorioallantoic Membrane (CAM) Assay and on Tumor and Endothelial Cell Proliferation.
inferredcites →https://doi.org/10.1248/bpb.28.563openalex-snapshot
Enhancement of All-trans Retinoic Acid-Induced HL-60 Cell Differentiation by Thalidomide and Its Metabolites
inferredcites →https://doi.org/10.1248/cpb.16.2289openalex-snapshot
Negative Effect of Thalidomide and Relative Substances on the Growth of HeLa Cells
inferredcites →https://doi.org/10.1248/cpb.42.1157openalex-snapshot
(S)-Form of .ALPHA.-Methyl-N(.ALPHA.)-phthalimidoglutarimide, but Not Its (R)-Form, Enhanced Phorbol Ester-Induced Tumor Necrosis Factor-.ALPHA. Production by Human Leukemia Cell HL-60: Implication of Optical Resolution of Thalidomidal Effects.
inferredcites →https://doi.org/10.1248/cpb.54.1709openalex-snapshot
Mono- and Dihydroxylated Metabolites of Thalidomide: Synthesis and TNF-.ALPHA. Production-Inhibitory Activity
inferredcites →https://doi.org/10.1517/14740338.3.1.47openalex-snapshot
Thalidomide: an old drug with new clinical applications
inferredcites →https://doi.org/10.2116/analscix.19.x51openalex-snapshot
Crystal Structure of 5'-Hydroxythalidomide In Vivo Metabolite of Thalidomide in Humans
inferredcites →https://doi.org/10.2174/138920006778017777openalex-snapshot
Thalidomide Metabolism and Hydrolysis: Mechanisms and Implications
inferredcites →https://doi.org/10.2535/ofaj.79.101openalex-snapshot
Effects of Thalidomide, Cytochrome P-450 and TNF-.ALPHA. on Angiogenesis in a Three-dimensional Collagen Gel-culture.
inferredcites →https://doi.org/10.3987/com-06-s(w)28openalex-snapshot
A Chiral Pool Approach toward the Synthesis of Thalidomide Metabolites
inferredcites →https://doi.org/10.4161/cbt.318openalex-snapshot
Pharmacogenetic Associations ofCYP2C19Genotype with In Vivo Metabolisms and Pharmacological Effects of Thalidomide
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4662555openalex-extracted
Enzymatic Synthesis and Biological Evaluation of Glycolipids as Potential Antibacterial, Antibiofilm and Antiquorum Sensing Agents
inferred← citeshttps://doi.org/10.1002/bmc.2892openalex-snapshot
Enantiomeric separation of tolperisone and eperisone by reversed‐phase HPLC with cellulose tris(3‐chloro‐4‐methylphenylcarbamate)‐coated chiral column
inferred← citeshttps://doi.org/10.1007/s00204-024-03930-zopenalex-snapshot
Thalidomide-induced limb malformations: an update and reevaluation
inferred← citeshttps://doi.org/10.1016/j.bioorg.2024.107855openalex-snapshot
Enhancing rhamnolipid production via immobilized Pseudomonas stutzeri lipase: A comparative study
inferred← citeshttps://doi.org/10.1016/j.bmcl.2009.02.108openalex-snapshot
Synthesis, configurational stability and stereochemical biological evaluations of (S)- and (R)-5-hydroxythalidomides
inferred← citeshttps://doi.org/10.1016/j.jbiotec.2021.06.021openalex-snapshot
Immobilization of Pseudomonas stutzeri lipase through Cross-linking Aggregates (CLEA) for reactions in Deep Eutectic Solvents
inferred← citeshttps://doi.org/10.1016/j.molcatb.2012.11.005openalex-snapshot
Lipase from Pseudomonas stutzeri: Purification, homology modelling and rational explanation of the substrate binding mode
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2008.12.043openalex-snapshot
Thalidomide protects against ischemic neuronal damage induced by focal cerebral ischemia in mice
inferred← citeshttps://doi.org/10.1016/j.tetasy.2013.09.022openalex-snapshot
Highly enantioselective enzymatic resolution of aromatic β-amino acid amides with Pd-catalyzed racemization
inferred← citeshttps://doi.org/10.1021/acs.cgd.3c01030openalex-snapshot
Chiral Inversion of Thalidomide During Crystal Growth by Sublimation
inferred← citeshttps://doi.org/10.1021/cr100287wopenalex-snapshot
Hydrolases in the Stereoselective Synthesis of N-Heterocyclic Amines and Amino Acid Derivatives
inferred← citeshttps://doi.org/10.1021/ol102818gopenalex-snapshot
Asymmetric Synthesis of Both Mirror Images of 3′-Fluorothalidomide by Enantiodivergent Fluorination Using a Single, Cinchona Alkaloid
inferred← citeshttps://doi.org/10.1021/ol201205topenalex-snapshot
Cu-Mediated Chemoselective Trifluoromethylation of Benzyl Bromides Using Shelf-Stable Electrophilic Trifluoromethylating Reagents
inferred← citeshttps://doi.org/10.1038/s41598-018-35457-6openalex-snapshot
Understanding the Thalidomide Chirality in Biological Processes by the Self-disproportionation of Enantiomers
inferred← citeshttps://doi.org/10.1039/c1gc15160fopenalex-snapshot
Pseudomonas stutzeri lipase: a useful biocatalyst for aminolysis reactions
inferred← citeshttps://doi.org/10.1039/c4sc03047hopenalex-snapshot
Self-disproportionation of enantiomers of thalidomide and its fluorinated analogue via gravity-driven achiral chromatography: mechanistic rationale and implications
inferred← citeshttps://doi.org/10.1080/10242422.2026.2731001openalex-snapshot
Biocatalytic carbohydrate modification using lipase from Stutzerimonas stutzeri : From regioselective hydrolysis to glycolipid synthesis
inferred← citeshttps://doi.org/10.1107/s1600536809002839openalex-snapshot
3-(2,6-Dioxopiperidin-3-yl)-3-azabicyclo[3.2.0]heptane-2,4-dione
inferred← citeshttps://doi.org/10.1246/cl.2009.1046openalex-snapshot
Design and Synthesis of Thalidomide–Deoxyribonucleoside Chimeras
inferred← citeshttps://doi.org/10.1248/cpb.58.110openalex-snapshot
Synthesis and Configurational Stability of (S)- and (R)-Deuteriothalidomides
inferred← citeshttps://doi.org/10.2174/187152009789735017openalex-snapshot
Current Status of Thalidomide and CC-5013 in the Treatment of Metastatic Prostate Cancer
inferred← citeshttps://doi.org/10.3390/ijms23042239openalex-snapshot
Enzymatic Synthesis and Molecular Modelling Studies of Rhamnose Esters Using Lipase from Pseudomonas stutzeri
inferred← citeshttps://doi.org/10.3390/molecules25235683openalex-snapshot
Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs
inferred← citeshttps://doi.org/10.4236/abb.2014.513115openalex-snapshot
Characterization of a Novel Pseudomonas stutzeri Lipase/Esterase with Potential Application in the Production of Chiral Secondary Alcohols
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