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Proteomics of Smad4 regulated transforming growth factor-beta signalling in colon cancer cells
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Binding to Intracellular Targets of the Metastasis-Inducing Protein, S100A4 (p9Ka)
inferredcites →https://doi.org/10.1007/s00109-007-0180-7openalex-snapshot
Involvement of deterioration in S100C/A11-mediated pathway in resistance of human squamous cancer cell lines to TGFβ-induced growth suppression
inferredcites →https://doi.org/10.1007/s11060-010-0277-7openalex-snapshot
The transglutaminase 2 gene is aberrantly hypermethylated in glioma
inferredcites →https://doi.org/10.1016/j.bbrc.2004.04.029openalex-snapshot
Proteomic analysis of the TGF-β signaling pathway in pancreatic carcinoma cells using stable RNA interference to silence Smad4 expression
inferredcites →https://doi.org/10.1016/j.canlet.2007.02.017openalex-snapshot
AKAP12 induces apoptotic cell death in human fibrosarcoma cells by regulating CDKI-cyclin D1 and caspase-3 activity
inferredcites →https://doi.org/10.1016/j.cellsig.2006.05.009openalex-snapshot
TGF-β receptor-binding proteins: Complex interactions
inferredcites →https://doi.org/10.1016/j.cytogfr.2005.09.009openalex-snapshot
Alterations in components of the TGF-β superfamily signaling pathways in human cancer
inferredcites →https://doi.org/10.1016/j.molcel.2007.02.005openalex-snapshot
Prolyl cis-trans Isomerization as a Molecular Timer in Crk Signaling
inferredcites →https://doi.org/10.1016/j.tibs.2004.03.008openalex-snapshot
New insights into TGF-β–Smad signalling
inferredcites →https://doi.org/10.1016/s0959-437x(01)00259-3openalex-snapshot
TGF-β signaling: positive and negative effects on tumorigenesis
inferredcites →https://doi.org/10.1021/pr050455topenalex-snapshot
Differential Protein Expression Profiling by iTRAQ−2DLC−MS/MS of Lung Cancer Cells Undergoing Epithelial-Mesenchymal Transition Reveals a Migratory/Invasive Phenotype
inferredcites →https://doi.org/10.1021/pr8006478openalex-snapshot
Temporal Quantitative Proteomics by iTRAQ 2D-LC-MS/MS and Corresponding mRNA Expression Analysis Identify Post-Transcriptional Modulation of Actin-Cytoskeleton Regulators During TGF-β-Induced Epithelial-Mesenchymal Transition
inferredcites →https://doi.org/10.1038/35087019openalex-snapshot
TGF-β-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation
inferredcites →https://doi.org/10.1038/labinvest.3780456openalex-snapshot
Cellular Retinol-Binding Protein-1 Expression and Modulation during In Vivo and In Vitro Myofibroblastic Differentiation of Rat Hepatic Stellate Cells and Portal Fibroblasts
inferredcites →https://doi.org/10.1038/nature02006openalex-snapshot
Smad-dependent and Smad-independent pathways in TGF-β family signalling
inferredcites →https://doi.org/10.1038/sj.onc.1202641openalex-snapshot
DPC4/SMAD4 mediated tumor suppression of colon carcinoma cells is associated with reduced urokinase expression
inferredcites →https://doi.org/10.1038/sj.onc.1206751openalex-snapshot
Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells
inferredcites →https://doi.org/10.1042/bj20090990openalex-snapshot
Functional interaction between Smad3 and S100A4 (metastatin-1) for TGF-β-mediated cancer cell invasiveness
inferredcites →https://doi.org/10.1074/jbc.275.15.11141openalex-snapshot
Interaction in Vivo and in Vitro of the Metastasis-inducing S100 Protein, S100A4 (p9Ka) with S100A1
inferredcites →https://doi.org/10.1074/jbc.m411580200openalex-snapshot
Galectin-1 Interacts with the α5β1 Fibronectin Receptor to Restrict Carcinoma Cell Growth via Induction of p21 and p27
inferredcites →https://doi.org/10.1074/mcp.m400129-mcp200openalex-snapshot
Multiplexed Protein Quantitation in Saccharomyces cerevisiae Using Amine-reactive Isobaric Tagging Reagents
inferredcites →https://doi.org/10.1074/mcp.t600050-mcp200openalex-snapshot
The Paragon Algorithm, a Next Generation Search Engine That Uses Sequence Temperature Values and Feature Probabilities to Identify Peptides from Tandem Mass Spectra
inferredcites →https://doi.org/10.1083/jcb.200312041openalex-snapshot
PKCα mediates TGFβ-induced growth inhibition of human keratinocytes via phosphorylation of S100C/A11
inferredcites →https://doi.org/10.1093/emboj/18.5.1345openalex-snapshot
TGF‐β induces fibronectin synthesis through a c‐Jun N‐terminal kinase‐dependent, Smad4‐independent pathway
inferredcites →https://doi.org/10.1093/emboj/19.8.1745openalex-snapshot
Transcriptional control by the TGF‐β/Smad signaling system
inferredcites →https://doi.org/10.1093/emboj/cdf366openalex-snapshot
TGF‐β receptor‐activated p38 MAP kinase mediates Smad‐independent TGF‐β responses
inferredcites →https://doi.org/10.1096/fj.07-083857openalex-snapshot
Transgelin is a direct target of TGF‐β/Smad3‐dependent epithelial cell migration in lung fibrosis
inferredcites →https://doi.org/10.1097/01.asn.0000108521.39082.e1openalex-snapshot
Chronic Renal Allograft Dysfunction
inferredcites →https://doi.org/10.1111/j.1349-7006.2007.00514.xopenalex-snapshot
Determination of metastasis‐associated proteins in non‐small cell lung cancer by comparative proteomic analysis
inferredcites →https://doi.org/10.1126/science.1071809openalex-snapshot
Signal Transduction by the TGF-β Superfamily
inferredcites →https://doi.org/10.1126/science.7761852openalex-snapshot
Inactivation of the Type II TGF-β Receptor in Colon Cancer Cells with Microsatellite Instability
inferredcites →https://doi.org/10.1128/mcb.25.18.8108-8125.2005openalex-snapshot
Smad4 Dependency Defines Two Classes of Transforming Growth Factor β (TGF-β) Target Genes and Distinguishes TGF-β-Induced Epithelial-Mesenchymal Transition from Its Antiproliferative and Migratory Responses
inferredcites →https://doi.org/10.1146/annurev.cb.06.110190.003121openalex-snapshot
The Transforming Growth Factor-beta Family
inferredcites →https://doi.org/10.1167/iovs.04-0535openalex-snapshot
Gene and Protein Expression Changes in Human Trabecular Meshwork Cells Treated with Transforming Growth Factor-
inferredcites →https://doi.org/10.1177/089686080802803s18openalex-snapshot
Transforming Growth Factor β1 Induces Epithelial–mesenchymal Transition by Activating the Jnk–SMAD3 Pathway in Rat Peritoneal Mesothelial Cells
inferredcites →https://doi.org/10.2217/fon.09.90openalex-snapshot
Mechanisms of the Epithelial–Mesenchymal Transition by TGF-β
inferredcites →https://doi.org/10.2741/1057openalex-snapshot
The 26S proteasome system in the signaling pathways of TGF-BETA superfamily
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Cadmium Hyperaccumulation Mechanism of Solanum Nigrum L. With Exploration from the Perspective of Differential Protein Expression Based on Itraq Proteomics Compared to its Zinc Accumulation Characteristic
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Cadmium Hyperaccumulation Mechanism of Solanum Nigrum L. With Exploration from the Perspective of Differential Protein Expression Based on Itraq Proteomics Compared to its Zinc Accumulation Characteristic
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Transgelin-2 in immunity: Its implication in cell therapy
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Quantitative proteomic analysis of cold‐responsive proteins in rice
inferred← citeshttps://doi.org/10.1002/pmic.201100036openalex-snapshot
Quantitative phosphoproteomics of transforming growth factor‐β signaling in colon cancer cells
inferred← citeshttps://doi.org/10.1002/pmic.201400147openalex-snapshot
From pathways to networks: Connecting dots by establishing protein–protein interaction networks in signaling pathways using affinity purification and mass spectrometry
inferred← citeshttps://doi.org/10.1002/prca.201200080openalex-snapshot
Quantitative mass spectrometry for colorectal cancer proteomics
inferred← citeshttps://doi.org/10.1002/prca.201500082openalex-snapshot
Mass spectrometry based translational proteomics for biomarker discovery and application in colorectal cancer
inferred← citeshttps://doi.org/10.1007/s10555-012-9360-1openalex-snapshot
Suppression of tumor and metastasis progression through the scaffolding functions of SSeCKS/Gravin/AKAP12
inferred← citeshttps://doi.org/10.1016/j.clinbiochem.2012.10.039openalex-snapshot
Proteomics in colorectal cancer translational research: Biomarker discovery for clinical applications
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2022.129717openalex-snapshot
Mechanism exploration of Solanum nigrum L. hyperaccumulating Cd compared to Zn from the perspective of metabolic pathways based on differentially expressed proteins using iTRAQ
inferred← citeshttps://doi.org/10.1016/j.plaphy.2016.03.024openalex-snapshot
iTRAQ-based proteomic analysis reveals the mechanisms of silicon-mediated cadmium tolerance in rice (Oryza sativa) cells
inferred← citeshttps://doi.org/10.1016/j.tibs.2019.05.004openalex-snapshot
Transgelin-2: Biochemical and Clinical Implications in Cancer and Asthma
inferred← citeshttps://doi.org/10.1021/acs.jproteome.2c00551openalex-snapshot
Multiomics of Colorectal Cancer Organoids Reveals Putative Mediators of Cancer Progression Resulting from SMAD4 Inactivation
inferred← citeshttps://doi.org/10.1038/s41598-018-32433-yopenalex-snapshot
A novel mechanism of plasminogen activation in epithelial and mesenchymal cells
inferred← citeshttps://doi.org/10.1097/md.0000000000045295openalex-snapshot
Exploration of upstream and downstream mechanisms of the TAGLN2 gene in pulmonary arterial hypertension
inferred← citeshttps://doi.org/10.1109/skima.2011.6163990openalex-snapshot
An ensemble greedy algorithm for feature selection in cancer genomics
inferred← citeshttps://doi.org/10.1111/age.12508openalex-snapshot
Genome‐wide proteomics analysis on longissimus muscles in Qinchuan beef cattle
inferred← citeshttps://doi.org/10.1126/scisignal.2004856openalex-snapshot
Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β
inferred← citeshttps://doi.org/10.1155/2012/289243openalex-snapshot
The Roles of Mitogen-Activated Protein Kinase Pathways in TGF-β-Induced Epithelial-Mesenchymal Transition
inferred← citeshttps://doi.org/10.1177/1010428317702650openalex-snapshot
Transgelin-2: A potential oncogenic factor
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Emerging Roles for SSeCKS/Gravin/AKAP12 in the Control of Cell Proliferation, Cancer Malignancy, and Barriergenesis
inferred← citeshttps://doi.org/10.1186/1479-5876-10-183openalex-snapshot
TGF-β – an excellent servant but a bad master
inferred← citeshttps://doi.org/10.1186/1756-9966-30-70openalex-snapshot
Reduced expression of SMAD4 in gliomas correlates with progression and survival of patients
inferred← citeshttps://doi.org/10.1186/s12885-024-12082-3openalex-snapshot
Transgelin-2, a novel cancer stem cell-related biomarker, is a diagnostic and therapeutic target for biliary tract cancer
inferred← citeshttps://doi.org/10.1186/s43141-021-00154-xopenalex-snapshot
Alterations of PTEN and SMAD4 methylation in diagnosis of breast cancer: implications of methyl II PCR assay
inferred← citeshttps://doi.org/10.12659/msm.883537openalex-snapshot
A proteomic study of potential VEGF-C-associated proteins in bladder cancer T24 cells
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Development and Validation of Serum Markers as Noninvasive Diagnostic Methods for Achalasia
inferred← citeshttps://doi.org/10.33540/1905openalex-snapshot
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inferred← citeshttps://doi.org/10.3389/fcell.2020.573859openalex-snapshot
Transgelins: Cytoskeletal Associated Proteins Implicated in the Metastasis of Colorectal Cancer
inferred← citeshttps://doi.org/10.3389/fcell.2021.606149openalex-snapshot
Transgelin-2: A Double-Edged Sword in Immunity and Cancer Metastasis
inferred← citeshttps://doi.org/10.3389/fcvm.2020.00115openalex-snapshot
Angiotensin Converting Enzyme Inhibitors (ACEIs) Decrease the Progression of Cardiac Fibrosis in Rheumatic Heart Disease Through the Inhibition of IL-33/sST2
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1627419openalex-snapshot
CXCR7-TAGLN2 protein complex regulates invasion and metastasis in papillary thyroid carcinoma: a potential therapeutic target
inferred← citeshttps://doi.org/10.3389/fpls.2013.00211openalex-snapshot
Proteomic comparison of basal endosperm in maize miniature1 mutant and its wild-type Mn1
inferred← citeshttps://doi.org/10.3390/biomedicines8120593openalex-snapshot
Oncolytic Adenovirus CD55-Smad4 Suppresses Cell Proliferation, Metastasis, and Tumor Stemness in Colorectal Cancer by Regulating Wnt/β-Catenin Signaling Pathway
inferred← citeshttps://doi.org/10.3390/ijms18102119openalex-snapshot
Transforming Growth Factor-β Drives the Transendothelial Migration of Hepatocellular Carcinoma Cells
inferred← citeshttps://doi.org/10.3390/ijms21103466openalex-snapshot
Proteomic Characterization of Colorectal Cancer Cells versus Normal-Derived Colon Mucosa Cells: Approaching Identification of Novel Diagnostic Protein Biomarkers in Colorectal Cancer
inferred← citeshttps://doi.org/10.3390/ijms242216076openalex-snapshot
Association of Germline Variation in Driver Genes with Breast Cancer Risk in Chilean Population
inferred← citeshttps://doi.org/10.3892/ol.2015.3442openalex-snapshot
SMAD4 expression in breast ductal carcinoma correlates with prognosis
inferred← citeshttps://doi.org/10.4172/jpb.1000412openalex-snapshot
Protein Markers Associated with an ALDH Sub-Population in Colorectal Cancer
inferred← citeshttps://doi.org/10.6084/m9.figshare.25449010openalex-snapshot
Additional file 1 of Transgelin-2, a novel cancer stem cell-related biomarker, is a diagnostic and therapeutic target for biliary tract cancer
inferred← citeshttps://doi.org/10.6084/m9.figshare.25449154openalex-snapshot
Additional file 2 of Transgelin-2, a novel cancer stem cell-related biomarker, is a diagnostic and therapeutic target for biliary tract cancer
inferred← citeshttps://doi.org/10.6084/m9.figshare.26695830openalex-snapshot
Additional file 3 of Transgelin-2, a novel cancer stem cell-related biomarker, is a diagnostic and therapeutic target for biliary tract cancer
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