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Applications of asymmetric organocatalysis in medicinal chemistry

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Chirality in Drug Research
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Asymmetric Phase Transfer Catalysis
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Hydrogen Bonding in Organic Synthesis
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Primary Amine‐Thioureas based on tert‐Butyl Esters of Natural Amino Acids as Organocatalysts for the Michael Reaction
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Asymmetric Synthesis of Maraviroc (UK‐427,857)
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Enantioselective Synthesis of Cyclic Thioureas via Mannich Reaction and Concise Synthesis of Highly Optically Active Methylthioimidazolines: Discovery of a More Potent Antipyretic Agent
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The Growing Impact of Catalysis in the Pharmaceutical Industry
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Primary Amine‐Thioureas with Improved Catalytic Properties for “Difficult” Michael Reactions: Efficient Organocatalytic Syntheses of (S)‐Baclofen, (R)‐Baclofen and (S)‐Phenibut
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High‐Yielding Synthesis of the Anti‐Influenza Neuramidase Inhibitor (−)‐Oseltamivir by Three “One‐Pot” Operations
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New Type of Asymmetric Cyclization to Optically Active Steroid CD Partial Structures
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Organocatalytic Asymmetric Michael Reaction of Cyclic 1,3‐Dicarbonyl Compounds and α,β‐Unsaturated Ketones—A Highly Atom‐Economic Catalytic One‐Step Formation of Optically Active Warfarin Anticoagulant
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In the Golden Age of Organocatalysis
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Organocatalytic Conjugate Addition of Malonates to α,β‐Unsaturated Aldehydes: Asymmetric Formal Synthesis of (−)‐Paroxetine, Chiral Lactams, and Lactones
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Asymmetric Aminocatalysis—Gold Rush in Organic Chemistry
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High‐Yielding Synthesis of the Anti‐Influenza Neuramidase Inhibitor (−)‐Oseltamivir by Three “One‐Pot” Operations
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Organocatalytic Michael Addition of Aldehydes to Protected 2‐Amino‐1‐Nitroethenes: The Practical Syntheses of Oseltamivir (Tamiflu) and Substituted 3‐Aminopyrrolidines
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One‐Pot Reactions Accelerate the Synthesis of Active Pharmaceutical Ingredients
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N‐Heterocyclic Carbene Catalyzed Domino Reactions
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A Rotaxane‐Based Switchable Organocatalyst
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Potent Inhibition of HIV‐1 Entry with a Chemically Programmed Antibody Aided by an Efficient Organocatalytic Synthesis
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Organocatalytic Michael Reaction of Nitroenamine Derivatives with Aldehydes: Short and Efficient Asymmetric Synthesis of (−)‐Oseltamivir
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High‐Yielding Synthesis of the Anti‐Influenza Neuraminidase Inhibitor (−)‐Oseltamivir by Two “One‐Pot” Sequences
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Squaramides: Bridging from Molecular Recognition to Bifunctional Organocatalysis
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Norstatines from Aldehydes by Sequential Organocatalytic α‐Amination and Passerini Reaction
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Organocatalytic Synthesis of Drugs and Bioactive Natural Products
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New Phenylglycine‐Derived Primary Amine Organocatalysts for the Preparation of Optically Active Warfarin
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Organocatalytic Enantioselective Michael Addition of 4‐Hydroxycoumarin to α,β‐Unsaturated Ketones: A Simple Synthesis of Warfarin
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Chiral Ionic Liquids Bearing O‐Silylated α,α‐Diphenyl (S)‐ or (R)‐Prolinol Units: Recoverable Organocatalysts for Asymmetric Michael Addition of Nitroalkanes to α,β‐Enals
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Organische Katalysatoren, LXI. Asymmetrische Synthesen mit Ketenen, I. Alkaloid‐katalysierte asymmetrische Synthesen von α‐Phenyl‐propionsäureestern
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Organische Katalysatoren. LXXI Asymmetrische Synthesen mit Ketenen. IV. Zusammenhänge zwischen dem räumlichen Bau einiger alkaloidartiger Katalysatoren und ihren stereospezifischen Wirkungen bei asymmetrischen Estersynthesen
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Peptide-Based Drug Design: Here and Now
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Organocatalyzed highly atom economic one pot synthesis of tetrahydropyridines as antimalarials
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Synthesis and HIV-1 integrase inhibitory activity of spiroundecane(ene) derivatives
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Organocatalytic synthesis and sterol 14α-demethylase binding interactions of enantioriched 3-(1H-1,2,4-triazol-1-yl)butyl benzoates
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Structure-based design and synthesis of novel P2/P3 modified, non-peptidic β-secretase (BACE-1) inhibitors
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Synthesis and comparative evaluation of 4-oxa- and 4-aza-podophyllotoxins as antiproliferative microtubule destabilizing agents
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Highly enantioselective organocatalytic synthesis of piperidines. Formal synthesis of (−)-Paroxetine
inferredcites →https://doi.org/10.1016/s0960-894x(99)00693-9openalex-snapshot
4-Aza-2,3-dehydro-4-deoxypodophyllotoxins: simple aza-podophyllotoxin analogues possessing potent cytotoxicity
inferredcites →https://doi.org/10.1021/cc100003copenalex-snapshot
Regioselective Synthesis and in Vitro Anticancer Activity of 4-Aza-podophyllotoxin Derivatives Catalyzed by l -Proline
inferredcites →https://doi.org/10.1021/cr068373ropenalex-snapshot
Small-Molecule H-Bond Donors in Asymmetric Catalysis
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Stronger Brønsted Acids
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New Strategies for Organic Catalysis: The First Highly Enantioselective Organocatalytic Diels−Alder Reaction
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Design of Potent Inhibitors for Human Brain Memapsin 2 (β-Secretase)
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Efficient catalytic asymmetric alkylations. 1. Enantioselective synthesis of (+)-indacrinone via chiral phase-transfer catalysis
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A Unique Approach to the Concise Synthesis of Highly Optically Active Spirooxazolines and the Discovery of a More Potent Oxindole-Type Phytoalexin Analogue
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Inotropic Activity of Hydroindene Amidinohydrazones
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Design, Synthesis, and Biological Evaluation of the Combinatorial Library with a New Spirodiketopiperazine Scaffold. Discovery of Novel Potent and Selective Low-Molecular-Weight CCR5 Antagonists
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Antitumor Compounds Based on a Natural Product Consensus Pharmacophore
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Asymmetric synthesis of bicyclic intermediates of natural product chemistry
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Efficient Synthesis of Novel NK1 Receptor Antagonists: Selective 1,4-Addition of Grignard Reagents to 6-Chloronicotinic Acid Derivatives
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Substrate-Controlled and Organocatalytic Asymmetric Synthesis of Carbocyclic Amino Acid Dipeptide Mimetics
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Organocatalytic Asymmetric Tandem Michael Addition−Hemiacetalization: A Route to Chiral Dihydrocoumarins, Chromanes, and 4H-Chromenes
inferredcites →https://doi.org/10.1021/jo101704bopenalex-snapshot
Asymmetric Synthesis of Telcagepant, a CGRP Receptor Antagonist for the Treatment of Migraine
inferredcites →https://doi.org/10.1021/jo202020mopenalex-snapshot
One-Pot Enantioselective Synthesis of Functionalized Pyranocoumarins and 2-Amino-4 H -chromenes: Discovery of a Type of Potent Antibacterial Agent
inferredcites →https://doi.org/10.1021/jo901409dopenalex-snapshot
Organocatalytic Asymmetric Friedel−Crafts Alkylation/Cyclization Cascade Reaction of 1-Naphthols and α,β-Unsaturated Aldehydes: An Enantioselective Synthesis of Chromanes and Dihydrobenzopyranes
inferredcites →https://doi.org/10.1021/ol0485417openalex-snapshot
Direct Organocatalytic Asymmetric Aldol Reactions of α-Amino Aldehydes: Expedient Syntheses of Highly Enantiomerically Enriched anti-β-Hydroxy-α-amino Acids
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Substrate-Directed Stereoselectivity in Vicinal Diamine-Catalyzed Synthesis of Warfarin
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Asymmetric Aza-Mannich Addition: Synthesis of Modified Chiral 2-(Ethylthio)-thiazolone Derivatives with Anticancer Potency
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Asymmetric Synthesis of γ-Nitroesters by an Organocatalytic One-Pot Strategy
inferredcites →https://doi.org/10.1021/ol800108uopenalex-snapshot
Organocatalytic Asymmetric Total Synthesis of (R)-Rolipram and Formal Synthesis of (3S,4R)-Paroxetine
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Pilot-Plant Preparation of 3,4-Dihydropyridin-2-one Derivatives, the Core Structures of P2X 7 Receptor Antagonists
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Asymmetric and Diastereoselective Conjugate Addition Reactions: C–C Bond Formation at Large Scale
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Practical Syntheses of Chiral α-Amino Acids and Chiral Half-Esters by Kinetic Resolution of Urethane-Protected α-Amino Acid N-Carboxyanhydrides and Desymmetrization of Cyclic meso-Anhydrides with New Modified Cinchona Alkaloid Catalysts
inferredcites →https://doi.org/10.1038/nchem.215openalex-snapshot
Concise synthesis of ricciocarpin A and discovery of a more potent analogue
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Organocatalytic cascade reactions as a new tool in total synthesis
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New medicines to improve control and contribute to the eradication of malaria
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Metal-free organocatalysis through explicit hydrogen bonding interactions
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The synthesis of chromenes, chromanes, coumarins and related heterocycles via tandem reactions of salicylic aldehydes or salicylic imines with α,β-unsaturated compounds
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Binaphthol-derived phosphoric acid as a versatile catalyst for enantioselective carbon–carbon bond forming reactions
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Asymmetric organocatalysis in total synthesis – a trial by fire
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Mechanisms in aminocatalysis
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Squaramides: physical properties, synthesis and applications
inferredcites →https://doi.org/10.1039/c1cc14379dopenalex-snapshot
Highly enantioselective Friedel–Crafts alkylation reaction catalyzed by rosin-derived tertiary amine–thiourea: synthesis of modified chromanes with anticancer potency
inferredcites →https://doi.org/10.1039/c1gc15118eopenalex-snapshot
Efficient “on water” organocatalytic protocol for the synthesis of optically pure warfarin anticoagulant
inferredcites →https://doi.org/10.1039/c1ob06133jopenalex-snapshot
Design, synthesis and biological evaluation of optically pure functionalized spiro[5,5]undecane-1,5,9-triones as HIV-1 inhibitors
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Discovery of 2-aminobuta-1,3-enynes in asymmetric organocascade catalysis: construction of drug-like spirocyclic cyclohexanes having five to six contiguous stereocenters
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Cinchona Alkaloids in Asymmetric Organocatalysis
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Chiral Phosphoric Acids as Versatile Catalysts for Enantioselective Transformations
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Metal-Free Chiral Phosphoric Acid or Chiral Metal Phosphate as Active Catalyst in the Activation of N-Acyl Aldimines
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Thiol-Free Synthesis of Oseltamivir and Its Analogues via Organocatalytic Michael Additions of Oxyacetaldehydes to 2-Acylaminonitroalkenes
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Efficient Asymmetric Synthesis of β-Amino Acid BAY 10-8888/PLD-118, a Novel Antifungal for the Treatment of Yeast Infections
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Discovery of new antimalarial chemotypes through chemical methodology and library development
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Substrate and Inhibitor Profile of BACE (β-Secretase) and Comparison with Other Mammalian Aspartic Proteases
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Deletion of μ-Opioid Receptor in Mice Alters the Development of Acute Neuroinflammation
inferredcites →https://doi.org/10.1126/science.290.5489.150openalex-snapshot
Structure of the Protease Domain of Memapsin 2 (β-Secretase) Complexed with Inhibitor
inferredcites →https://doi.org/10.1128/aac.42.9.2197openalex-snapshot
Molecular Mode of Action of the Antifungal β-Amino Acid BAY 10-8888
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Chiral Phosphoric Acids as Versatile Catalysts for Enantioselective Carbon–Carbon Bond Forming Reactions
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CCR5 inhibitors in HIV-1 therapy
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Aspartic Proteases in Drug Discovery
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Enantioselective Carbon-Carbon Bond Forming Reactions Catalyzed by Chiral Phosphoric Acid Catalysts
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Chirality - A New Era of Therapeutics
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New Targets, New Hope: Novel Drug Targets for Curbing Malaria

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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γ′‐Selective Functionalization of Cyclic Enones: Construction of a Chiral Quaternary Carbon Center by [4+2] Cycloaddition/Retro‐Mannich Reaction with 3‐Substituted Maleimides
inferred← citeshttps://doi.org/10.1002/anie.201609390openalex-snapshot
Organocatalytic Friedel–Crafts Alkylation/Lactonization Reaction of Naphthols with 3‐Trifluoroethylidene Oxindoles: The Asymmetric Synthesis of Dihydrocoumarins
inferred← citeshttps://doi.org/10.1002/anie.201807134openalex-snapshot
The Hydrazine–O 2 Redox Couple as a Platform for Organocatalytic Oxidation: Benzo[ c ]cinnoline‐Catalyzed Oxidation of Alkyl Halides to Aldehydes
inferred← citeshttps://doi.org/10.1002/anie.201912043openalex-snapshot
Enantioenriched Methylene‐Bridged Benzazocanes Synthesis by Organocatalytic and Superacid Activations
inferred← citeshttps://doi.org/10.1002/anie.202205633openalex-snapshot
Excitation‐Dependent Circularly Polarized Luminescence from Helical Assemblies Based on Tartaric Acid‐Derived Acylhydrazones
inferred← citeshttps://doi.org/10.1002/anie.202217724openalex-snapshot
Highly Enantioselective Construction of Multifunctional Silicon‐Stereogenic Silacycles by Asymmetric Enamine Catalysis
inferred← citeshttps://doi.org/10.1002/asia.201301549openalex-snapshot
Synergy, Compatibility, and Innovation: Merging Lewis Acids with Stereoselective Enamine Catalysis
inferred← citeshttps://doi.org/10.1002/asia.201600013openalex-snapshot
Hydrogen‐Bonding Network Promoted [3+2] Cycloaddition: Asymmetric Catalytic Construction of Spiro‐pseudoindoxyl Derivatives
inferred← citeshttps://doi.org/10.1002/asia.201800608openalex-snapshot
Transition‐Metal‐Free Multicomponent Approach to Stereoenriched Cyclopentyl‐isoxazoles through C−C Bond Cleavage
inferred← citeshttps://doi.org/10.1002/asia.201801296openalex-snapshot
Organocatalysts Derived from Unnatural α‐Amino Acids: Scope and Applications
inferred← citeshttps://doi.org/10.1002/asia.202300370openalex-snapshot
Blossoming of Polyenamine Catalysis in Asymmetric Synthesis: Scope and Future Applications
inferred← citeshttps://doi.org/10.1002/cctc.201300399openalex-snapshot
Electrosteric Activation by using Ion‐Tagged Prolines: A Combined Experimental and Computational Investigation
inferred← citeshttps://doi.org/10.1002/cctc.201402973openalex-snapshot
Efficient Organocatalyst Supported on a Simple Ionic Liquid as a Recoverable System for the Asymmetric Diels–Alder Reaction in the Presence of Water
inferred← citeshttps://doi.org/10.1002/cctc.201500455openalex-snapshot
Recent Advances in Organocatalytic Kinetic Resolution for the Synthesis of Functionalized Products
inferred← citeshttps://doi.org/10.1002/cctc.201601527openalex-snapshot
Gold(I)‐Mediated Thiourea Organocatalyst Activation: A Synergic Effect for Asymmetric Catalysis
inferred← citeshttps://doi.org/10.1002/cctc.201701975openalex-snapshot
Serendipitous Observation of Liquid‐Phase Size Selectivity inside a Mesoporous Silica Nanoreactor in the Reaction of Chromene with Formic Acid
inferred← citeshttps://doi.org/10.1002/cctc.201901129openalex-snapshot
From Immobilization to Catalyst Use: A Complete Continuous‐Flow Approach Towards the Use of Immobilized Organocatalysts
inferred← citeshttps://doi.org/10.1002/cctc.202000463openalex-snapshot
Synthesis of Polycyclic Spiro Pyrrolidone Derivatives via DBU‐Catalyzed Diastereoselective Vinylogous Aldol‐Michael Cascade Reaction
inferred← citeshttps://doi.org/10.1002/cctc.202400031openalex-snapshot
A C3‐Symmetric Amino Organocatalyst for Asymmetric Synthesis of Warfarin and Analogues: Mechanistic Insight from ESI‐MS Spectrometry and Computational Calculations
inferred← citeshttps://doi.org/10.1002/cctc.202402021openalex-snapshot
Enantioselective Preparation of Chiral Succinimide Derivatives by Mechanochemical Catalytic Michael Addition
inferred← citeshttps://doi.org/10.1002/celc.201600187openalex-snapshot
N‐Heterocyclic Carbenes and Parent Cations: Acidity, Nucleophilicity, Stability, and Hydrogen Bonding—Electrochemical Study and Ab Initio Calculations
inferred← citeshttps://doi.org/10.1002/celc.201700992openalex-snapshot
Electrogenerated N‐Heterocyclic Olefins: Stability and Catalytic Ability
inferred← citeshttps://doi.org/10.1002/chem.201302127openalex-snapshot
Organocatalytic Asymmetric Synthesis of Tetracyclic Pyridocarbazole Derivatives by Using a Diels–Alder/aza‐Michael/Aldol Condensation Domino Reaction
inferred← citeshttps://doi.org/10.1002/chem.201302220openalex-snapshot
Chiral Hypervalent Iodine Reagents: Synthesis and Reactivity
inferred← citeshttps://doi.org/10.1002/chem.201402373openalex-snapshot
Organocatalyzed Step‐Growth Polymerization through Desymmetrization of Cyclic Anhydrides: Synthesis of Chiral Polyesters
inferred← citeshttps://doi.org/10.1002/chem.201402947openalex-snapshot
One‐Pot Asymmetric Synthesis of Quaternary Pyrroloindolones through a Multicatalytic N‐Allylation/Hydroacylation Sequence
inferred← citeshttps://doi.org/10.1002/chem.201405038openalex-snapshot
Aminocatalysis: Beyond Steric Shielding and Hydrogen‐Bonding
inferred← citeshttps://doi.org/10.1002/chem.201500660openalex-snapshot
Dienamine and Friedel–Crafts One‐Pot Synthesis, and Antitumor Evaluation of Diheteroarylalkanals
inferred← citeshttps://doi.org/10.1002/chem.201503063openalex-snapshot
Core‐Scaffold‐Inspired Asymmetric Synthesis of Polysubstituted Chiral Hexahydropyridazines that Potently Inhibit Breast Cancer Cell Proliferation by Inducing Apoptosis
inferred← citeshttps://doi.org/10.1002/chem.201503352openalex-snapshot
Organocatalytic Asymmetric Conjugate Additions to Cyclopent‐1‐enecarbaldehyde: A Critical Assessment of Organocatalytic Approaches towards the Telaprevir Bicyclic Core
inferred← citeshttps://doi.org/10.1002/chem.201602884openalex-snapshot
Design of Selenium‐Based Chiral Chemical Probes for Simultaneous Enantio‐ and Chemosensing of Chiral Carboxylic Acids with Remote Stereogenic Centers by NMR Spectroscopy
inferred← citeshttps://doi.org/10.1002/chem.201705010openalex-snapshot
Chemo‐ and Stereoselective Cross Rauhut–Currier‐Type Reaction of Tri‐substituted Alkenes Containing Trifluoromethyl Groups
inferred← citeshttps://doi.org/10.1002/chem.201905704openalex-snapshot
Ambident Reactivity of Imidazolium Cations as Evidence of the Dynamic Nature of N‐Heterocyclic Carbene‐Mediated Organocatalysis
inferred← citeshttps://doi.org/10.1002/chem.202302764openalex-snapshot
Nucleophilicity of 4‐(Alkylthio)‐3‐imidazoline Derived Enamines
inferred← citeshttps://doi.org/10.1002/chin.201322216openalex-snapshot
ChemInform Abstract: Applications of Asymmetric Organocatalysis in Medicinal Chemistry
inferred← citeshttps://doi.org/10.1002/chir.22303openalex-snapshot
A Practical and Stereoselective Organocatalytic Alkylation of Aldehydes with Benzodithiolylium Tetrafluoroborate
inferred← citeshttps://doi.org/10.1002/chir.22794openalex-snapshot
High‐performance liquid chromatographic enantioseparation of N‐aryl‐thioureidoalkylphosphonates and thiourylenedi(alkylphosphonates) on polysaccharide‐based chiral stationary phases
inferred← citeshttps://doi.org/10.1002/chir.23137openalex-snapshot
Chiral Imidazolidin‐4‐one with catalytic amount of Dicationic ionic liquid act as a recoverable and reusable Organocatalyst for asymmetric Diels‐Alder reaction
inferred← citeshttps://doi.org/10.1002/chir.23633openalex-snapshot
Chiral measure of chiral polyhedrons
inferred← citeshttps://doi.org/10.1002/cjoc.201400836openalex-snapshot
One‐Pot Synthesis of Aliphatic Nitro Compounds by Michael/retro‐Claisen Fragmentation Domino Reaction
inferred← citeshttps://doi.org/10.1002/cmdc.202200104openalex-snapshot
Design, Synthesis, and Biological Evaluation of Tetrahydro‐α‐carbolines as Akt1 Inhibitors That Inhibit Colorectal Cancer Cell Proliferation
inferred← citeshttps://doi.org/10.1002/cphc.201501063openalex-snapshot
Catalysts Encapsulated in Molecular Machines
inferred← citeshttps://doi.org/10.1002/cplu.201600062openalex-snapshot
A pH‐Responsive Soluble‐Polymer‐Based Homogeneous Ruthenium Catalyst for Highly Efficient Asymmetric Transfer Hydrogenation (ATH)
inferred← citeshttps://doi.org/10.1002/cssc.201902500openalex-snapshot
Valorization of Waste: Sustainable Organocatalysts from Renewable Resources
inferred← citeshttps://doi.org/10.1002/ejoc.201300331openalex-snapshot
Bifunctional Primary Amine‐Squaramide Catalyzed Enantioselective Intramolecular Michael Addition of Keto‐enones: A Convenient Process to the Stereocontrolled Construction of trans‐Dihydrobenzofuran Skeletons
inferred← citeshttps://doi.org/10.1002/ejoc.201402243openalex-snapshot
Highly Enantioselective Michael Addition of Malonates to β‐CF3‐β‐(3‐Indolyl)nitroalkenes: Construction of Trifluoromethylated All‐Carbon Quaternary Stereogenic Centres
inferred← citeshttps://doi.org/10.1002/ejoc.201403180openalex-snapshot
Cinchona‐Derived Picolinamides: Effective Organocatalysts for Stereoselective Imine Hydrosilylation
inferred← citeshttps://doi.org/10.1002/ejoc.201500616openalex-snapshot
Construction of Diverse and Functionalized 2H‐Chromenes by Organocatalytic Multicomponent Reactions
inferred← citeshttps://doi.org/10.1002/ejoc.201501618openalex-snapshot
Enantioselective Catalytic Domino Aza‐Michael–Henry Reactions: One‐Pot Asymmetric Synthesis of 3‐Nitro‐1,2‐dihydroquinolines via Iminium Activation
inferred← citeshttps://doi.org/10.1002/ejoc.201601357openalex-snapshot
Organocatalyst Efficiency in the α‐Aminoxylation and α‐Hydrazination of Carbonyl Derivatives in Aqueous Media or in a Ball‐Mill
inferred← citeshttps://doi.org/10.1002/ejoc.201700133openalex-snapshot
Chiral Imidazolium Ionic Liquids Derived from (S)‐Prolinamine as Organocatalysts in the Asymmetric Michael Reaction and Michael‐Aldol Cascade Reaction under Solvent‐Free Conditions
inferred← citeshttps://doi.org/10.1002/ejoc.201800236openalex-snapshot
Organocatalytic Enantioselective Synthesis of Tetrahydropyridines
inferred← citeshttps://doi.org/10.1002/ejoc.201800746openalex-snapshot
Divergent Synthesis of Quinazolines Using Organocatalytic Domino Strategies under Aerobic Conditions
inferred← citeshttps://doi.org/10.1002/ejoc.201801339openalex-snapshot
Synthesis of a New N‐Diaminophosphoryl‐N′‐[(2S)‐2‐pyrrolidinylmethyl]thiourea as a Chiral Organocatalyst for the Stereoselective Michael Addition of Cyclohexanone to Nitrostyrenes and Chalcones – Application in Cascade Processes for the Synthesis of Polycyclic Systems
inferred← citeshttps://doi.org/10.1002/ejoc.201901344openalex-snapshot
Hydrogen Bonding and Internal or External Lewis or Brønsted Acid Assisted (Thio)urea Catalysts
inferred← citeshttps://doi.org/10.1002/ejoc.202000235openalex-snapshot
Synthesis of Chiral 3,4‐Disubstituted Pyrrolidines with Antibacterial Properties
inferred← citeshttps://doi.org/10.1002/ejoc.202100502openalex-snapshot
Organocatalytic Desymmetrization of Meso‐Aziridines Via Asymmetric Intramolecular Rearrangement
inferred← citeshttps://doi.org/10.1002/ejoc.202101042openalex-snapshot
Asymmetric Organocatalysis Accelerated via Self‐Assembled Minimal Structures
inferred← citeshttps://doi.org/10.1002/ejoc.202101171openalex-snapshot
Enantioselective Povarov Reactions: An Update of a Powerful Catalytic Synthetic Methodology
inferred← citeshttps://doi.org/10.1002/ejoc.202200962openalex-snapshot
Fast Transition Metal‐Free Synthesis of Functionalized Oxindoles and Dihydroquinoline‐2‐ones Under Microwave Irradiation
inferred← citeshttps://doi.org/10.1002/ejoc.202400373openalex-snapshot
2‐Methylene‐1,2‐dihydropyridines (2‐pyNHOs): Highly Nucleophilic Enamines
inferred← citeshttps://doi.org/10.1002/ejoc.202401048openalex-snapshot
Synthetic Approaches for the Construction of Chiral Aziridines
inferred← citeshttps://doi.org/10.1002/ejoc.202500338openalex-snapshot
A C 3 ‐Symmetric Diphenylethylendiamine‐Based Catalyst in the Asymmetric Michael Addition of α,β‐Unsaturated Ketones with 4‐Hydroxycoumarin and 4‐Hydroxyquinolin‐2‐One
inferred← citeshttps://doi.org/10.1002/ejoc.70549openalex-snapshot
Redox Properties of Catalytically Generated Iminium Ions From α,β‐Unsaturated Aldehydes and Chiral Secondary Amines
inferred← citeshttps://doi.org/10.1002/elps.70061openalex-snapshot
Mirror‐Image β‐ l ‐Cyclodextrin as a Chiral Pseudophase in Capillary Electrophoresis
inferred← citeshttps://doi.org/10.1002/slct.201601165openalex-snapshot
Phenyl (2‐quinolyl) methanol: A Valuable Reagent for Metal‐Free Reduction of Aromatic Nitro Compounds and Imines
inferred← citeshttps://doi.org/10.1002/slct.201601213openalex-snapshot
Short Synthesis of Novel Recyclable Chiral Bifunctional Thioureas from Aminoalkyl Polystyrene and their use as Organocatalysts in Stereoselective aza‐Henry Reaction.
inferred← citeshttps://doi.org/10.1002/slct.201601859openalex-snapshot
Recyclable Silica‐Supported Proline Sulphonamide Organocatalysts for Asymmetric Direct Aldol Reaction.
inferred← citeshttps://doi.org/10.1002/slct.201904059openalex-snapshot
Amino‐Acid‐Mediated Aerobic Oxidation of Organoborons for the Synthesis of Phenolic Derivatives Using Single Electron Transfer
inferred← citeshttps://doi.org/10.1002/slct.202002765openalex-snapshot
Recent Advances in Pyridine‐Based Organocatalysis and its Application towards Valuable Chemical Transformations
inferred← citeshttps://doi.org/10.1002/slct.202100679openalex-snapshot
Recent Advances in Organocatalytic Asymmetric Michael Addition Reactions to α, β‐Unsaturated Nitroolefins
inferred← citeshttps://doi.org/10.1002/slct.202300204openalex-snapshot
The Importance of Organocatalysis (Asymmetric and Non‐Asymmetric) in Agrochemicals
inferred← citeshttps://doi.org/10.1002/slct.202403964openalex-snapshot
Dipeptidic Proline Amide–Isothiouronium Salt Organocatalysts for Enantiodivergent Conjugate Addition Reactions Between Aldehydes and Nitroolefins
inferred← citeshttps://doi.org/10.1002/tcr.201500286openalex-snapshot
Harnessing the Versatility of Continuous-Flow Processes: Selective and Efficient Reactions
inferred← citeshttps://doi.org/10.1002/tcr.201800047openalex-snapshot
Organocatalytic Asymmetric Cascade Reactions Based on Gamma‐Nitro Carbonyl Compound
inferred← citeshttps://doi.org/10.1002/tcr.201800190openalex-snapshot
Organocatalyzed Asymmetric Friedel‐Crafts Reactions: An Update
inferred← citeshttps://doi.org/10.1002/tcr.201800199openalex-snapshot
Catalytic Asymmetric Synthesis of Spiropyrazolones and their Application in Medicinal Chemistry
inferred← citeshttps://doi.org/10.1007/7355_2021_119openalex-snapshot
Organocatalysis in Continuous Flow for Drug Discovery
inferred← citeshttps://doi.org/10.1007/978-3-642-36199-9_127-2openalex-snapshot
Polymer Catalysts
inferred← citeshttps://doi.org/10.1007/s00044-016-1589-8openalex-snapshot
POM analyses and evaluation of in vitro antimicrobial, antitumor activity of 4H-pyrimido[2,1-b]benzothiazole derivatives
inferred← citeshttps://doi.org/10.1007/s00253-026-13717-0openalex-snapshot
Highly enantioselective reduction of benzophenones by engineered Geotrichum candidum alcohol dehydrogenase
inferred← citeshttps://doi.org/10.1007/s00706-015-1486-8openalex-snapshot
Optimization of stereoselective Michael addition of 2-(pentan-3-yloxy)acetaldehyde to N-[(Z)-2-nitroethenyl]acetamide with the aid of design of experiments
inferred← citeshttps://doi.org/10.1007/s10562-017-2015-7openalex-snapshot
A New Type of Magnetically-Recoverable Heteropolyacid Nanocatalyst Supported on Zirconia-Encapsulated Fe3O4 Nanoparticles as a Stable and Strong Solid Acid for Multicomponent Reactions
inferred← citeshttps://doi.org/10.1007/s11164-015-2249-1openalex-snapshot
Recyclable task-specific acidic ionic liquid [NMP]H2PO4: Microwave-assisted, efficient one-pot, two-step tandem synthesis of fused thiazolo[2,3-b]quinazolinone and thiazolo[2,3-b]quinazoline derivatives
inferred← citeshttps://doi.org/10.1007/s11164-020-04361-yopenalex-snapshot
Synthesis of a novel acidic ionic liquid catalyst and its application for preparation of pyridines via a cooperative vinylogous anomeric-based oxidation
inferred← citeshttps://doi.org/10.1007/s11164-025-05635-zopenalex-snapshot
Chiral guanidine-functionalized chloramphenicol base: a novel ultra-low-loading bifunctional organocatalyst for highly enantioselective alcoholysis of meso-cyclic anhydride
inferred← citeshttps://doi.org/10.1007/s11172-021-3163-xopenalex-snapshot
Novel C2-symmetric phenylglycine derivatives as organocatalysts of the Michael reaction between nitroalkenes and ketones
inferred← citeshttps://doi.org/10.1007/s11237-022-09710-zopenalex-snapshot
Modern Approaches to Synthetic Design of Chiral α-Tertiary Amines Based on Trifluoromethylcontaining Ketimines: A Review
inferred← citeshttps://doi.org/10.1007/s13738-017-1157-2openalex-snapshot
Magnetic nanoparticles grafted l-carnosine dipeptide: remarkable catalytic activity in water at room temperature
inferred← citeshttps://doi.org/10.1016/b978-0-12-813594-5.00010-2openalex-snapshot
Nanomagnetic-Supported Catalysts
inferred← citeshttps://doi.org/10.1016/b978-0-443-18611-0.00025-5openalex-snapshot
Organic synthetic methodology-based new scaffolds in drug discovery
inferred← citeshttps://doi.org/10.1016/bs.acat.2025.10.003openalex-snapshot
Homogeneous catalysis in continuous flow. Metal and organo-catalysis
inferred← citeshttps://doi.org/10.1016/bs.aihch.2015.04.002openalex-snapshot
The Literature of Heterocyclic Chemistry, Part XIII, 2012–2013
inferred← citeshttps://doi.org/10.1016/j.catcom.2013.08.015openalex-snapshot
1,4-Michael additions of cyclic-β-ketoesters catalyzed by DNA in aqueous media
inferred← citeshttps://doi.org/10.1016/j.chroma.2014.04.080openalex-snapshot
Enantiomeric separation of biaryl atropisomers using cyclofructan based chiral stationary phases
inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.12.002openalex-snapshot
Synthesis and biological evaluation of cyanoaziridine phosphine oxides and phosphonates with antiproliferative activity
inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.115009openalex-snapshot
Discovery of tetrahydrofuranyl spirooxindole-based SMYD3 inhibitors against gastric cancer via inducing lethal autophagy
inferred← citeshttps://doi.org/10.1016/j.jcat.2013.05.010openalex-snapshot
Potassium fluoride: A convenient, non-covalent support for the immobilization of organocatalysts through strong hydrogen bonds
inferred← citeshttps://doi.org/10.1016/j.jcat.2024.115366openalex-snapshot
Novel porous organic polymer supported chloramphenicol base derivatives: A highly enantioselective, recyclable heterogeneous organocatalyst for asymmetric desymmetrization reaction
inferred← citeshttps://doi.org/10.1016/j.jcou.2020.01.024openalex-snapshot
Carboxylative cyclization of propargylic alcohols with carbon dioxide: A facile and Green route to α-methylene cyclic carbonates
inferred← citeshttps://doi.org/10.1016/j.jiec.2015.03.035openalex-snapshot
Sustainable alternative protocols for the multicomponent synthesis of spiro-4H-pyrans catalyzed by 4-dimethylaminopyridine
inferred← citeshttps://doi.org/10.1016/j.matchemphys.2019.122298openalex-snapshot
Graphene-based recyclable and bifunctional heterogeneous chiral catalyst for direct asymmetric aldol reaction
inferred← citeshttps://doi.org/10.1016/j.mcat.2017.03.003openalex-snapshot
9-Amino(9-deoxy)epi-cinchona alkaloid-tethered aluminium phosphonate architectures for heterogeneous cooperative catalysis: asymmetric aldol and double-Michael cascade reaction
inferred← citeshttps://doi.org/10.1016/j.mcat.2019.110744openalex-snapshot
Knoevenagel-Doebner condensation promoted by chitosan as a reusable solid base catalyst
inferred← citeshttps://doi.org/10.1016/j.mcat.2020.110814openalex-snapshot
Innovative catalysis in Michael addition reactions for C-X bond formation
inferred← citeshttps://doi.org/10.1016/j.mcat.2020.111071openalex-snapshot
Co-catalyst and solvent free nitrogen rich triazole based organocatalysts for cycloaddition of CO2 into epoxide
inferred← citeshttps://doi.org/10.1016/j.mencom.2015.11.001openalex-snapshot
Novel approaches to pharmacology-oriented and energy rich organic nitrogen–oxygen systems
inferred← citeshttps://doi.org/10.1016/j.mencom.2016.09.001openalex-snapshot
Challenges in the development of organic and hybrid molecular systems
inferred← citeshttps://doi.org/10.1016/j.mencom.2017.11.001openalex-snapshot
Recent advances in synthesis of organic nitrogen–oxygen systems for medicine and materials science
inferred← citeshttps://doi.org/10.1016/j.molcata.2016.03.013openalex-snapshot
Weakly bounded intermediates as a previous step towards highly-enantioselective iminium type additions of β-keto-sulfoxides and -sulfones
inferred← citeshttps://doi.org/10.1016/j.nantod.2013.07.002openalex-snapshot
Superhydrophobic, chiral, and mesoporous TsDPEN copolymer coordinated to ruthenium species as an efficient catalyst for asymmetric transfer hydrogenation
inferred← citeshttps://doi.org/10.1016/j.nantod.2026.103136openalex-snapshot
Nanocarbons as organocatalysts for asymmetric reactions: A critical evaluation against conventional catalysis
inferred← citeshttps://doi.org/10.1016/j.rechem.2026.103825openalex-snapshot
Unravelling the mechanism of thiourea-enabled N-heterocyclic carbene catalysis in dihydrocoumarin synthesis: A theoretical investigation
inferred← citeshttps://doi.org/10.1016/j.supflu.2015.11.004openalex-snapshot
Asymmetric catalytic synthesis of functionalized tetrahydroquinolines in supercritical fluids
inferred← citeshttps://doi.org/10.1016/j.tet.2013.05.116openalex-snapshot
Asymmetric Michael addition of 4H-thiopyran-4-one to nitroolefins catalyzed by diamine mono-N-sulfonamide and its application to concise synthesis of enantiopure multiring heterocycles
inferred← citeshttps://doi.org/10.1016/j.tet.2013.10.033openalex-snapshot
Task-specific ionic liquid incorporating anionic heteropolyacid-catalyzed Hantzsch and Mannich multicomponent reactions. Ionic liquid effect probed by ESI-MS(/MS)
inferred← citeshttps://doi.org/10.1016/j.tet.2013.12.007openalex-snapshot
tert-Butyl esters of tripeptides based on Pro-Phe as organocatalysts for the asymmetric aldol reaction in aqueous or organic medium
inferred← citeshttps://doi.org/10.1016/j.tet.2014.04.016openalex-snapshot
Evaluation of mono- and dipeptides as organocatalysts for enantioselective aldol reaction
inferred← citeshttps://doi.org/10.1016/j.tet.2014.07.023openalex-snapshot
Organocatalytic transformations of alkynals, alkynones, propriolates, and related electron-deficient alkynes
inferred← citeshttps://doi.org/10.1016/j.tet.2014.12.078openalex-snapshot
tert-Butyl ester or benzylamide of the dipeptide Pro-Gly as organocatalysts for the asymmetric aldol reaction
inferred← citeshttps://doi.org/10.1016/j.tet.2016.07.067openalex-snapshot
Stereoselective reactions of nitro compounds in the synthesis of natural compound analogs and active pharmaceutical ingredients
inferred← citeshttps://doi.org/10.1016/j.tet.2018.03.054openalex-snapshot
Combining prolinamides with 2-pyrrolidinone: Novel organocatalysts for the asymmetric aldol reaction
inferred← citeshttps://doi.org/10.1016/j.tet.2018.06.015openalex-snapshot
Recent advances in the asymmetric catalytic synthesis of chiral 3-hydroxy and 3-aminooxindoles and derivatives: Medicinally relevant compounds
inferred← citeshttps://doi.org/10.1016/j.tet.2018.07.043openalex-snapshot
Recyclable C2-symmetric tertiary amine-squaramide organocatalysts: Design and application to asymmetric synthesis of γ-nitrocarbonyl compounds
inferred← citeshttps://doi.org/10.1016/j.tet.2018.08.038openalex-snapshot
Proline dipeptides containing fluorine moieties as oganocatalysts for the asymmetric aldol reaction
inferred← citeshttps://doi.org/10.1016/j.tet.2018.11.052openalex-snapshot
Phosphinoyl-aziridines as a new class of chiral catalysts for enantioselective Michael addition
inferred← citeshttps://doi.org/10.1016/j.tet.2021.132143openalex-snapshot
Recent developments in next generation (S)-proline-derived chiral organocatalysts
inferred← citeshttps://doi.org/10.1016/j.tet.2024.134112openalex-snapshot
Novel centratherin derivatives: Molecular docking design, asymmetric synthesis, and antitumoral activity
inferred← citeshttps://doi.org/10.1016/j.tet.2024.134129openalex-snapshot
Some contributions to three relevant areas in organic stereochemistry during the last decade: (1) conformational effects, (2) asymmetric organocatalysis, and (3) mechanoenzymatic processes
inferred← citeshttps://doi.org/10.1016/j.tetasy.2013.03.002openalex-snapshot
Organocatalytic asymmetric synthesis of 3-amino-2-oxindole derivatives bearing a tetra-substituted stereocenter
inferred← citeshttps://doi.org/10.1016/j.tetasy.2014.06.009openalex-snapshot
Enantioselective Michael addition of α,α-disubstituted aldehydes to nitroolefins catalyzed by a pyrrolidine-pyrazole
inferred← citeshttps://doi.org/10.1016/j.tetasy.2014.07.005openalex-snapshot
Asymmetric Michael addition of aldehydes to nitroolefins catalyzed by a pyrrolidine–pyrazole
inferred← citeshttps://doi.org/10.1016/j.tetasy.2014.10.014openalex-snapshot
Pyrrolidine-oxyimides: new chiral catalysts for enantioselective Michael addition of ketones to nitroolefins in water
inferred← citeshttps://doi.org/10.1016/j.tetasy.2014.12.007openalex-snapshot
tert-Butyl esters of peptides as organocatalysts for the asymmetric aldol reaction
inferred← citeshttps://doi.org/10.1016/j.tetasy.2015.04.010openalex-snapshot
A highly enantio- and diastereoselective direct aldol reaction in aqueous medium catalyzed by thiazolidine-based compounds
inferred← citeshttps://doi.org/10.1016/j.tetasy.2015.07.009openalex-snapshot
Pyrrolidine–oxyimide catalyzed asymmetric Michael addition of α,α-disubstituted aldehydes to nitroolefins
inferred← citeshttps://doi.org/10.1016/j.tetasy.2016.08.006openalex-snapshot
Pyrrolidine-HOBt: an oxytriazole catalyst for the enantioselective Michael addition of cyclohexanone to nitroolefins in water
inferred← citeshttps://doi.org/10.1016/j.tetasy.2017.02.005openalex-snapshot
Enantioselective Michael addition of aldehydes to nitroolefins catalyzed by pyrrolidine-HOBt
inferred← citeshttps://doi.org/10.1016/j.tetasy.2017.02.006openalex-snapshot
Evolution of synthetic routes towards homochiral Tapentadol
inferred← citeshttps://doi.org/10.1016/j.tetasy.2017.03.002openalex-snapshot
Solvent free, fast and asymmetric Michael additions of ketones to nitroolefins using chiral pyrrolidine–pyridone conjugate bases as organocatalysts
inferred← citeshttps://doi.org/10.1016/j.tetasy.2017.09.006openalex-snapshot
Thermal racemization of biaryl atropisomers
inferred← citeshttps://doi.org/10.1016/j.tetlet.2013.12.068openalex-snapshot
p-tert-Butylcalix[8]arene catalysed synthesis of 3,5-dinitrothiophene scaffolds: antiproliferative effect of some representative compounds on selective anticancer cell lines
inferred← citeshttps://doi.org/10.1016/j.tetlet.2014.07.075openalex-snapshot
Catalytic asymmetric reactions in alkaloid and terpenoid syntheses
inferred← citeshttps://doi.org/10.1016/j.tetlet.2015.04.053openalex-snapshot
Organocatalytic aldol addition reaction of cyclic hemiacetals to aldehydes
inferred← citeshttps://doi.org/10.1016/j.tetlet.2016.05.012openalex-snapshot
The impact of asymmetric organocatalysis in dearomatization and aromatization of carbocycles: increasing molecular complexity and diversity
inferred← citeshttps://doi.org/10.1016/j.tetlet.2018.05.053openalex-snapshot
Enantioselective organocatalytic approach to δ-lactones bearing a fused cyclohexanone scaffold
inferred← citeshttps://doi.org/10.1016/j.tetlet.2018.07.020openalex-snapshot
Asymmetric synthesis and antiviral activity of novel chiral amino-pyrimidine derivatives
inferred← citeshttps://doi.org/10.1016/j.tetlet.2019.05.065openalex-snapshot
Recent applications of mechanochemistry in enantioselective synthesis
inferred← citeshttps://doi.org/10.1016/j.tetlet.2019.151131openalex-snapshot
N-Heterocyclic carbene as a Brønsted base catalyst for the amination of naphthol derivatives and alcoholysis of glutaric anhydrides
inferred← citeshttps://doi.org/10.1016/j.tetlet.2020.152792openalex-snapshot
Polysulfonate supported chiral diamine-nickel catalysts: Synthesis and applications
inferred← citeshttps://doi.org/10.1016/j.trechm.2021.12.010openalex-snapshot
Recent advances towards organocatalytic enantioselective desymmetrizing reactions
inferred← citeshttps://doi.org/10.1021/acs.accounts.9b00549openalex-snapshot
Organocatalytic Asymmetric Synthesis of Indole-Based Chiral Heterocycles: Strategies, Reactions, and Outreach
inferred← citeshttps://doi.org/10.1021/acs.chemmater.8b02884openalex-snapshot
Hierarchically Porous Single Nanocrystals of Bimetallic Metal–Organic Framework for Nanoreactors with Enhanced Conversion
inferred← citeshttps://doi.org/10.1021/acs.chemrev.6b00156openalex-snapshot
Enantioselective Organocatalyzed Transformations of β-Ketoesters
inferred← citeshttps://doi.org/10.1021/acs.chemrev.6b00657openalex-snapshot
Organocatalysis in Inert C–H Bond Functionalization
inferred← citeshttps://doi.org/10.1021/acs.chemrev.7b00183openalex-snapshot
The Hitchhiker’s Guide to Flow Chemistry
inferred← citeshttps://doi.org/10.1021/acs.chemrev.9b00338openalex-snapshot
Chiral Hypervalent Iodines: Active Players in Asymmetric Synthesis
inferred← citeshttps://doi.org/10.1021/acs.joc.0c02081openalex-snapshot
Organocatalyzed Sulfa-Michael Addition of Thiophenols on Trisubstituted α-Fluoroacrylates, a Straightforward Access to Chiral Fluorinated Compounds
inferred← citeshttps://doi.org/10.1021/acs.joc.1c00124openalex-snapshot
Asymmetric 1,4-Michael Addition in Aqueous Medium Using Hydrophobic Chiral Organocatalysts
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