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Cross talk between cancer and immune cells: exploring complex dynamics in a microfluidic environment

https://doi.org/10.1039/c2lc40887b
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1 of the 50 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-21): 10.1158/0008-5472.can-10-1296 (notice 2017-07-02).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Type I IFN regulate DC turnover in vivo
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Evolutionary method for the assembly of rigid protein fragments
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Human macrophage function and physical exercise: phagocytic and histochemical studies
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Stepping out of the flow: capillary extravasation in cancer metastasis
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A multi-functional role of interferon regulatory factor-8 in solid tumor and myeloid cell biology
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Peptide vaccines derived from a malarial surface antigen: effects of dose and adjuvants on immunogenicity
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Role of chemokines in tumor growth
inferredcites →https://doi.org/10.1016/j.cbpa.2010.08.016openalex-snapshot
Tumors on chips: oncology meets microfluidics
inferredcites →https://doi.org/10.1016/j.clim.2009.09.008openalex-snapshot
IFNβ-1a therapy for multiple sclerosis expands regulatory CD8+ T cells and decreases memory CD8+ subset: A longitudinal 1-year study
inferredcites →https://doi.org/10.1016/j.copbio.2006.08.009openalex-snapshot
Engineering tissues for in vitro applications
inferredcites →https://doi.org/10.1016/j.molmed.2010.01.003openalex-snapshot
Chemokines and chemokine receptors: new insights into cancer-related inflammation
inferredcites →https://doi.org/10.1016/j.molonc.2010.06.006openalex-snapshot
Progress in understanding melanoma propagation
inferredcites →https://doi.org/10.1016/s0092-8674(00)81348-3openalex-snapshot
Immunodeficiency and Chronic Myelogenous Leukemia-like Syndrome in Mice with a Targeted Mutation of the ICSBP Gene
inferredcites →https://doi.org/10.1038/nature05058openalex-snapshot
The origins and the future of microfluidics
inferredcites →https://doi.org/10.1038/nature05063openalex-snapshot
Cells on chips
inferredcites →https://doi.org/10.1038/nature06385openalex-snapshot
Isolation of rare circulating tumour cells in cancer patients by microchip technology
inferredcites →https://doi.org/10.1038/nature07567openalex-snapshot
Efficient tumour formation by single human melanoma cells
inferredcites →https://doi.org/10.1038/ni.f.212openalex-snapshot
Interstitial leukocyte migration and immune function
inferredcites →https://doi.org/10.1038/ni1102-991openalex-snapshot
Cancer immunoediting: from immunosurveillance to tumor escape
inferredcites →https://doi.org/10.1038/nmat2013openalex-snapshot
The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder
inferredcites →https://doi.org/10.1038/nprot.2006.316openalex-snapshot
Microfluidic culture platform for neuroscience research
inferredcites →https://doi.org/10.1038/nprot.2007.30openalex-snapshot
In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro
inferredcites →https://doi.org/10.1038/nprot.2009.234openalex-snapshot
Soft lithography for micro- and nanoscale patterning
inferredcites →https://doi.org/10.1038/nprot.2012.051openalex-snapshot
Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels
inferredcites →https://doi.org/10.1038/nrc3080openalex-snapshot
The physics of cancer: the role of physical interactions and mechanical forces in metastasis
inferredcites →https://doi.org/10.1038/nrd3681openalex-snapshot
Diagnosing the decline in pharmaceutical R&D efficiency
inferredcites →https://doi.org/10.1038/nri2102openalex-snapshot
Real and artificial immune systems: computing the state of the body
inferredcites →https://doi.org/10.1039/b707399mopenalex-snapshot
Multi-step microfluidic device for studying cancer metastasis
inferredcites →https://doi.org/10.1039/b807585aopenalex-snapshot
Cell migration into scaffolds under co-culture conditions in a microfluidic platform
inferredcites →https://doi.org/10.1039/b818401aopenalex-snapshot
Engineering microscale cellular niches for three-dimensional multicellular co-cultures
inferredcites →https://doi.org/10.1039/b901377fopenalex-snapshot
A micro cell culture analog (µCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs
inferredcites →https://doi.org/10.1039/b908595eopenalex-snapshot
Spontaneous migration of cancer cells under conditions of mechanical confinement
inferredcites →https://doi.org/10.1039/b915147hopenalex-snapshot
Towards a human-on-chip: Culturing multiple cell types on a chip with compartmentalized microenvironments
inferredcites →https://doi.org/10.1039/c004675bopenalex-snapshot
A microfluidic platform for probing small artery structure and function
inferredcites →https://doi.org/10.1039/c0ib00055hopenalex-snapshot
Biological applications of microfluidic gradient devices
inferredcites →https://doi.org/10.1039/c0ib00063aopenalex-snapshot
Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects
inferredcites →https://doi.org/10.1039/c1lc20557aopenalex-snapshot
Ensembles of engineered cardiac tissues for physiological and pharmacological study: Heart on a chip
inferredcites →https://doi.org/10.1039/c2ib00176dopenalex-snapshot
Organs-on-chips: breaking the in vitro impasse
inferredcites →https://doi.org/10.1039/c2lc40089hopenalex-snapshot
Microengineered physiological biomimicry: Organs-on-Chips
inferredcites →https://doi.org/10.1073/pnas.0903269107openalex-snapshot
Geometric cues for directing the differentiation of mesenchymal stem cells
inferredcites →https://doi.org/10.1073/pnas.0906504107openalex-snapshot
Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs
inferredcites →https://doi.org/10.1073/pnas.1014920108openalex-snapshot
Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19
inferredcites →https://doi.org/10.1126/science.1221063openalex-snapshot
A Decade of Imaging Cellular Motility and Interaction Dynamics in the Immune System
inferredcites →https://doi.org/10.1158/0008-5472.can-07-1228openalex-snapshot
Host Immunosurveillance Controls Tumor Growth via IFN Regulatory Factor-8–Dependent Mechanisms
inferredcites →https://doi.org/10.1158/0008-5472.can-10-1296openalex-snapshot
Molecular Mechanism of MART-1+/A*0201+ Human Melanoma Resistance to Specific CTL-Killing Despite Functional Tumor–CTL Interaction
inferredcites →https://doi.org/10.1158/1078-0432.ccr-11-2232openalex-snapshot
Role of Apollon in Human Melanoma Resistance to Antitumor Agents That Activate the Intrinsic or the Extrinsic Apoptosis Pathways
inferredcites →https://doi.org/10.1182/blood-2003-09-3007openalex-snapshot
ICSBP is critically involved in the normal development and trafficking of Langerhans cells and dermal dendritic cells
inferredcites →https://doi.org/10.1182/blood-2005-11-4490openalex-snapshot
ICSBP/IRF-8 differentially regulates antigen uptake during dendritic-cell development and affects antigen presentation to CD4+ T cells
inferredcites →https://doi.org/10.1182/blood.v99.9.3263openalex-snapshot
Type I interferons produced by dendritic cells promote their phenotypic and functional activation
inferredcites →https://doi.org/10.4049/jimmunol.134.4.2405openalex-snapshot
The murine IL 2 receptor. III. Cellular requirements for the induction of IL 2 receptor expression on T cell subpopulations.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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The Intersection of Biomaterials, Tissue Engineering, and Immuno-oncology
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Fluid dynamic design for mitigating undesired cell effects and its application to testis cell response testing to endocrine disruptors
inferred← citeshttps://doi.org/10.1186/s13046-019-1086-2openalex-snapshot
3D models in the new era of immune oncology: focus on T cells, CAF and ECM
inferred← citeshttps://doi.org/10.1186/s13046-022-02335-zopenalex-snapshot
A roadmap for translational cancer glycoimmunology at single cell resolution
inferred← citeshttps://doi.org/10.1360/n972015-01055openalex-snapshot
Cell migration with microfluidic chips
inferred← citeshttps://doi.org/10.1371/journal.pone.0341962openalex-snapshot
Validation of an agent-based model for cell interactions in a microfluidic chip
inferred← citeshttps://doi.org/10.1557/adv.2016.337openalex-snapshot
Single Cell Interrogation using Optofluidic Platforms for Systems Immunology
inferred← citeshttps://doi.org/10.17816/onco516562openalex-snapshot
Three-dimensional cell models for studying tumor–immune interactions and testing immunotherapeutic drugs
inferred← citeshttps://doi.org/10.18609/ioi.2022.41openalex-snapshot
Preclinical models for development of immune–oncology therapies
inferred← citeshttps://doi.org/10.18632/oncotarget.26306openalex-snapshot
A combined microfluidic-transcriptomic approach to characterize the extravasation potential of cancer cells
inferred← citeshttps://doi.org/10.18632/oncotarget.6070openalex-snapshot
A bladder cancer microenvironment simulation system based on a microfluidic co-culture model
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2357747/v1openalex-snapshot
Validation of in vitro and in vivo personalized cancer treatment assays for head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.21203/rs.3.rs-4093618/v1openalex-snapshot
Germinal Center Dark Zone harbors ATR-dependent determinants of T-cell exclusion that are also identified in aggressive lymphoma
inferred← citeshttps://doi.org/10.2174/0113816128305296240523112043openalex-snapshot
Construction, Features and Regulatory Aspects of Organ-chip for Drug Delivery Applications: Advances and Prospective
inferred← citeshttps://doi.org/10.3109/1547691x.2014.891677openalex-snapshot
A multidisciplinary study usingin vivotumor models and microfluidic cell-on-chip approach to explore the cross-talk between cancer and immune cells
inferred← citeshttps://doi.org/10.3389/fbioe.2022.945149openalex-snapshot
A multi-organ-on-chip to recapitulate the infiltration and the cytotoxic activity of circulating NK cells in 3D matrix-based tumor model
inferred← citeshttps://doi.org/10.3389/fgene.2022.969723openalex-snapshot
Microfluidic devices: The application in TME modeling and the potential in immunotherapy optimization
inferred← citeshttps://doi.org/10.3389/fimmu.2022.770465openalex-snapshot
Organoid Models for Precision Cancer Immunotherapy
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1175503openalex-snapshot
3D cancer models: One step closer to in vitro human studies
inferred← citeshttps://doi.org/10.3389/fmed.2022.971726openalex-snapshot
In vitro models as tools for screening treatment options of head and neck cancer
inferred← citeshttps://doi.org/10.3389/fmolb.2021.627454openalex-snapshot
Oncoimmunology Meets Organs-on-Chip
inferred← citeshttps://doi.org/10.3389/fonc.2013.00090openalex-snapshot
The Tumor Microenvironment: A Pitch for Multiple Players
inferred← citeshttps://doi.org/10.3389/fonc.2013.00256openalex-snapshot
Getting to Know Ovarian Cancer Ascites: Opportunities for Targeted Therapy-Based Translational Research
inferred← citeshttps://doi.org/10.3389/fphar.2019.00100openalex-snapshot
From Petri Dishes to Organ on Chip Platform: The Increasing Importance of Machine Learning and Image Analysis
inferred← citeshttps://doi.org/10.3390/axioms10040243openalex-snapshot
Estimation Algorithm for a Hybrid PDE–ODE Model Inspired by Immunocompetent Cancer-on-Chip Experiment
inferred← citeshttps://doi.org/10.3390/axioms12100930openalex-snapshot
Sensitivity Analysis of a 2D Stochastic Agent-Based and PDE Diffusion Model for Cancer-on-Chip Experiments
inferred← citeshttps://doi.org/10.3390/bioengineering5020029openalex-snapshot
A 3D Microfluidic Model to Recapitulate Cancer Cell Migration and Invasion
inferred← citeshttps://doi.org/10.3390/books978-3-03897-232-7openalex-snapshot
Advances in Micro-Bioreactor Design for Organ Cell Studies
inferred← citeshttps://doi.org/10.3390/books978-3-03921-563-8openalex-snapshot
Microfluidics for Cells and Other Organisms
inferred← citeshttps://doi.org/10.3390/cancers10050151openalex-snapshot
Organoids Provide an Important Window on Inflammation in Cancer
inferred← citeshttps://doi.org/10.3390/cancers11111664openalex-snapshot
IL-33 Promotes CD11b/CD18-Mediated Adhesion of Eosinophils to Cancer Cells and Synapse-Polarized Degranulation Leading to Tumor Cell Killing
inferred← citeshttps://doi.org/10.3390/cancers12051173openalex-snapshot
Breast Fibroblasts and ECM Components Modulate Breast Cancer Cell Migration through the Secretion of MMPs in a 3D Microfluidic Co-Culture Model
inferred← citeshttps://doi.org/10.3390/cancers13215586openalex-snapshot
Interplay between Cellular and Non-Cellular Components of the Tumour Microenvironment in Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.3390/condmat4020058openalex-snapshot
Efficient Spatial Sampling for AFM-Based Cancer Diagnostics: A Comparison between Neural Networks and Conventional Data Analysis
inferred← citeshttps://doi.org/10.3390/ma12182945openalex-snapshot
The Tumor-on-Chip: Recent Advances in the Development of Microfluidic Systems to Recapitulate the Physiology of Solid Tumors
inferred← citeshttps://doi.org/10.3390/math10081338openalex-snapshot
An Agent-Based Interpretation of Leukocyte Chemotaxis in Cancer-on-Chip Experiments
inferred← citeshttps://doi.org/10.3390/math9060688openalex-snapshot
Mass-Preserving Approximation of a Chemotaxis Multi-Domain Transmission Model for Microfluidic Chips
inferred← citeshttps://doi.org/10.3390/mi13040587openalex-snapshot
Uniform Tumor Spheroids on Surface-Optimized Microfluidic Biochips for Reproducible Drug Screening and Personalized Medicine
inferred← citeshttps://doi.org/10.3390/mi15101195openalex-snapshot
Microfluidic Applications in Prostate Cancer Research
inferred← citeshttps://doi.org/10.3390/mi15121444openalex-snapshot
Microfluidic Technologies in Advancing Cancer Research
inferred← citeshttps://doi.org/10.3390/mi9120665openalex-snapshot
In Situ Analysis of Interactions between Fibroblast and Tumor Cells for Drug Assays with Microfluidic Non-Contact Co-Culture
inferred← citeshttps://doi.org/10.3390/microarrays5020011openalex-snapshot
Living Cell Microarrays: An Overview of Concepts
inferred← citeshttps://doi.org/10.3390/nano11061476openalex-snapshot
Recent Advances in the Label-Free Characterization of Exosomes for Cancer Liquid Biopsy: From Scattering and Spectroscopy to Nanoindentation and Nanodevices
inferred← citeshttps://doi.org/10.34133/bmef.0110openalex-snapshot
Graph-Based 3-Dimensional Spatial Gene Neighborhood Networks of Single Cells in Gels and Tissues
inferred← citeshttps://doi.org/10.4018/ijgbl.2016040101openalex-snapshot
Board Games and Board Game Design as Learning Tools for Complex Scientific Concepts
inferred← citeshttps://doi.org/10.4155/fsoa-2016-0084openalex-snapshot
Microfluidic On-Chip Biomimicry for 3D Cell Culture: a Fit-For-Purpose Investigation From the End User Standpoint
inferred← citeshttps://doi.org/10.4161/onci.25476openalex-snapshot
The dual role of IRF8 in cancer immunosurveillance
inferred← citeshttps://doi.org/10.6084/m9.figshare.23902959openalex-snapshot
Additional file 2 of Fluid dynamic design for mitigating undesired cell effects and its application to testis cell response testing to endocrine disruptors
inferred← citeshttps://doi.org/10.70675/26c1db27za511z4c6fza617z433f0d0d141dopenalex-snapshot
the Role of the immunogenetic Profile of patients in response to chemotherapy
inferred← citeshttps://doi.org/10.70675/59967b38z299fz4ac9z8908zb34f743143d2openalex-snapshot
Mathematical modeling of cell migration in response to chemical and physical stimuli : from immune to endothelial cells
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