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Natalamycin A, an ansamycin from a termite-associated Streptomyces sp.

https://doi.org/10.1039/c4sc01136h
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/anie.200902152openalex-snapshot
Insects: True Pioneers in Anti‐Infective Therapy and What We Can Learn from Them
inferredcites →https://doi.org/10.1002/anie.201006165openalex-snapshot
Divergolides A–D from a Mangrove Endophyte Reveal an Unparalleled Plasticity in ansa‐Macrolide Biosynthesis
inferredcites →https://doi.org/10.1002/cbic.200500441openalex-snapshot
Biosynthesis of the Heat‐Shock Protein 90 Inhibitor Geldanamycin: New Insight into the Formation of the Benzoquinone Moiety
inferredcites →https://doi.org/10.1002/cbic.200800763openalex-snapshot
Rational Biosynthetic Engineering for Optimization of Geldanamycin Analogues
inferredcites →https://doi.org/10.1002/chin.201123198openalex-snapshot
ChemInform Abstract: Divergolides A—D from a Mangrove Endophyte Reveal an Unparalleled Plasticity in ansa‐Macrolide Biosynthesis.
inferredcites →https://doi.org/10.1007/s00248-011-9987-4openalex-snapshot
Exploring the Potential for Actinobacteria as Defensive Symbionts in Fungus-Growing Termites
inferredcites →https://doi.org/10.1016/j.bmcl.2006.12.041openalex-snapshot
Geldanamycin derivatives and neuroprotective effect on cultured P19-derived neurons
inferredcites →https://doi.org/10.1016/j.canlet.2009.07.010openalex-snapshot
Geldanamycin and its anti-cancer activities
inferredcites →https://doi.org/10.1016/j.tim.2009.05.005openalex-snapshot
Symbiont-mediated protection in insect hosts
inferredcites →https://doi.org/10.1016/j.tim.2009.09.006openalex-snapshot
Actinobacteria as mutualists: general healthcare for insects?
inferredcites →https://doi.org/10.1016/s0378-1097(02)01148-5openalex-snapshot
Cloning and characterization of a gene cluster for geldanamycin production inStreptomyces hygroscopicusNRRL 3602
inferredcites →https://doi.org/10.1021/cr030112jopenalex-snapshot
RifamycinMode of Action, Resistance, and Biosynthesis
inferredcites →https://doi.org/10.1021/cr200106vopenalex-snapshot
Computational Prediction of 1 H and 13 C Chemical Shifts: A Useful Tool for Natural Product, Mechanistic, and Synthetic Organic Chemistry
inferredcites →https://doi.org/10.1021/ja047769mopenalex-snapshot
Inactivation of the Carbamoyltransferase Gene Refines Post-Polyketide Synthase Modification Steps in the Biosynthesis of the Antitumor Agent Geldanamycin
inferredcites →https://doi.org/10.1021/ja064863popenalex-snapshot
Relationship Among Ligand Conformations in Solution, in the Solid State, and at the Hsp90 Binding Site: Geldanamycin and Radicicol
inferredcites →https://doi.org/10.1021/ja2087147openalex-snapshot
Broad Substrate Specificity of the Amide Synthase in S. hygroscopicus—New 20-Membered Macrolactones Derived from Geldanamycin
inferredcites →https://doi.org/10.1021/ja3089394openalex-snapshot
The Correct Structure of Aquatolide—Experimental Validation of a Theoretically-Predicted Structural Revision
inferredcites →https://doi.org/10.1021/jo00088a047openalex-snapshot
Tandem [3,3]-Sigmatropic Rearrangements in an Ansamycin: Stereospecific Conversion of an (S)-Allylic Alcohol to an (S)-Allylic Amine Derivative
inferredcites →https://doi.org/10.1021/np2000446openalex-snapshot
Prediction of the Structure of Nobilisitine A Using Computed NMR Chemical Shifts
inferredcites →https://doi.org/10.1021/np3001738openalex-snapshot
Identification of 4,5-Dihydro-4-hydroxygeldanamycins As Shunt Products of Geldanamycin Biosynthesis
inferredcites →https://doi.org/10.1021/np4000679openalex-snapshot
19-[(1′S,4′R)-4′-Hydroxy-1′-methoxy-2′-oxopentyl]geldanamycin, a Natural Geldanamycin Analogue from Streptomyces hygroscopicus 17997
inferredcites →https://doi.org/10.1021/ol201383wopenalex-snapshot
The Missing C-17 O-Methyltransferase in Geldanamycin Biosynthesis
inferredcites →https://doi.org/10.1021/ol301043popenalex-snapshot
Microtermolides A and B from Termite-Associated Streptomyces sp. and Structural Revision of Vinylamycin
inferredcites →https://doi.org/10.1038/ismej.2011.14openalex-snapshot
Cellulose-degrading bacteria associated with the invasive woodwasp Sirex noctilio
inferredcites →https://doi.org/10.1038/ja.2011.39openalex-snapshot
A pair of sulfur-containing geldanamycin analogs, 19-S-methylgeldanamycin and 4,5-dihydro- 19-S-methylgeldanamycin, from Streptomyces hygroscopicus 17997
inferredcites →https://doi.org/10.1038/ja.2013.31openalex-snapshot
Methanethiol as a catabolite of methionine provides methylthio- group for chemical formation of 19-S-methylgeldanamycin and 17,19-dimethylthioherbimycin A
inferredcites →https://doi.org/10.1038/ja.2013.77openalex-snapshot
Bacterial symbionts in agricultural systems provide a strategic source for antibiotic discovery
inferredcites →https://doi.org/10.1038/ja.2013.94openalex-snapshot
Identification of 6-demethoxy-6-methylgeldanamycin and its implication of geldanamycin biosynthesis
inferredcites →https://doi.org/10.1038/nchem.1596openalex-snapshot
Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90
inferredcites →https://doi.org/10.1038/srep01030openalex-snapshot
Aerobic deconstruction of cellulosic biomass by an insect-associated Streptomyces
inferredcites →https://doi.org/10.1038/srep03250openalex-snapshot
The fungus-growing termite Macrotermes natalensis harbors bacillaene-producing Bacillus sp. that inhibit potentially antagonistic fungi
inferredcites →https://doi.org/10.1039/c1cc11574jopenalex-snapshot
Bacterial symbionts and natural products
inferredcites →https://doi.org/10.1039/c3np70012gopenalex-snapshot
Targeting heat-shock-protein 90 (Hsp90) by natural products: geldanamycin, a show case in cancer therapy
inferredcites →https://doi.org/10.1073/pnas.91.18.8324openalex-snapshot
Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation.
inferredcites →https://doi.org/10.1074/jbc.m312799200openalex-snapshot
Geldanamycin-associated Inhibition of Intracellular Trafficking Is Attributed to a Co-purified Activity
inferredcites →https://doi.org/10.1107/s0021889807059870openalex-snapshot
Determination of absolute structure using Bayesian statistics on Bijvoet differences
inferredcites →https://doi.org/10.1111/j.1574-6976.2011.00313.xopenalex-snapshot
Streptomyces as symbionts: an emerging and widespread theme?
inferredcites →https://doi.org/10.1128/aem.71.8.4862-4871.2005openalex-snapshot
Insights into the Biosynthesis of the Benzoquinone Ansamycins Geldanamycin and Herbimycin, Obtained by Gene Sequencing and Disruption
inferredcites →https://doi.org/10.1271/bbb.110361openalex-snapshot
Novel 4,5-Dihydro-thiazinogeldanamycin in agdmPMutant Strain ofStreptomyces hygroscopicus17997
inferredcites →https://doi.org/10.1371/journal.pone.0094166openalex-snapshot
Biochemical Properties and Atomic Resolution Structure of a Proteolytically Processed β-Mannanase from Cellulolytic Streptomyces sp. SirexAA-E
inferredcites →https://doi.org/10.4014/jmb.1206.06026openalex-snapshot
New Geldanamycin Analogs from Streptomyces hygroscopicus
inferredcites →https://doi.org/10.7164/antibiotics.23.442openalex-snapshot
GELDANAMYCIN, A NEW ANTIBIOTIC
inferredcites →https://doi.org/10.7164/antibiotics.53.1310openalex-snapshot
Reblastatin, a Novel Benzenoid Ansamycin-type Cell Cycle Inhibitor.
inferredcites →https://doi.org/10.7164/antibiotics.57.421openalex-snapshot
Isolation and Characterization of Novel Geldanamycin Analogues

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Termite sanitary behaviour and their associated bacteria protect against latent Xylaria and entomopathogenic Metarhizium
inferred← citeshttps://doi.org/10.1002/cbdv.202000140openalex-snapshot
Hexokinase II Inhibitory Effect of Secondary Metabolites Derived from a Streptomyces sp. Associated with Mud Dauber Wasp
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Expanding the Rubterolone Family: Intrinsic Reactivity and Directed Diversification of PKS‐derived Pyrans
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ChemInform Abstract: Natalamycin A, an Ansamycin from a Termite‐Associated Streptomyces sp.
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The Fungus-Growing Termites: Biology, Damage on Tropical Crops and Specific Management
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New Strategies to Activate Secondary Metabolism in Streptomyces
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Local hypoxia generated by live burial is effective in weed control within termite fungus farms
inferred← citeshttps://doi.org/10.1007/s00248-017-0972-4openalex-snapshot
Diversity, Antimicrobial Activity, and Biosynthetic Potential of Cultivable Actinomycetes Associated with Lichen Symbiosis
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In Vitro Studies Reveal that Pseudomonas, from Odontotermes obesus Colonies, can Function as a Defensive Mutualist as it Prevents the Weedy Fungus While Keeping the Crop Fungus Unaffected
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Streptomyces formicae sp. nov., a novel actinomycete isolated from the head of Camponotus japonicus Mayr
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Fungus-Farming Termites Selectively Bury Weedy Fungi that Smell Different from Crop Fungi
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Mikrobielle Interaktionen – eine chemische Schatztruhe
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Considerations of the chemical biology of microbial natural products provide an effective drug discovery strategy
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Diversity and antagonistic potential of Actinobacteria from the fungus-growing termite Odontotermes formosanus
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Building Castles on the Ground: Conversations Between Ecologists and Engineers
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Antileishmanial macrolides from ant-associated Streptomyces sp. ISID311
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Ansamycin derivatives from the marine-derived Streptomyces sp. SCSGAA 0027 and their cytotoxic and antiviral activities
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inferred← citeshttps://doi.org/10.1016/j.fitote.2024.106238openalex-snapshot
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Regenerative edible insects for food, feed, and sustainable livelihoods in Nigeria: Consumption, potential and prospects
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Extraction and purification of an antimicrobial bioactive element from lichen associated Streptomyces olivaceus LEP7 against wound inhabiting microbial pathogens
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Tryptoquivalines W and X, two new compounds from a Hawaiian fungal strain and their biological activities
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Geldanamycin, a Naturally Occurring Inhibitor of Hsp90 and a Lead Compound for Medicinal Chemistry
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Termisoflavones A–C, Isoflavonoid Glycosides from Termite-Associated Streptomyces sp. RB1
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.6c00814openalex-snapshot
N -Acetylcysteine-Conjugated Benzoxazomycins and Hydroxymycotrienin Derivatives from a Hymenoptera-Associated Streptomyces sp. SID10815
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.7b00426openalex-snapshot
Deinococcucins A–D, Aminoglycolipids from Deinococcus sp., a Gut Bacterium of the Carpenter Ant Camponotus japonicus
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Absolute Configuration and Corrected NMR Assignment of 17-Hydroxycyclooctatin, a Fused 5–8–5 Tricyclic Diterpene
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Pseudoxylallemycins A–F, Cyclic Tetrapeptides with Rare Allenyl Modifications Isolated from Pseudoxylaria sp. X802: A Competitor of Fungus-Growing Termite Cultivars
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Naphthoquinone–Oxindole Alkaloids, Coprisidins A and B, from a Gut-Associated Bacterium in the Dung Beetle, Copris tripartitus
inferred← citeshttps://doi.org/10.1021/acs.orglett.6b03831openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.orglett.7b00545openalex-snapshot
Linear Peptides Are the Major Products of a Biosynthetic Pathway That Encodes for Cyclic Depsipeptides
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Tundrenone: An Atypical Secondary Metabolite from Bacteria with Highly Restricted Primary Metabolism
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Microbial Cross-Talk: Unlocking the Cytochalasin Diversity from a Termite-Associated Xylaria
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inferred← citeshttps://doi.org/10.1038/s41467-019-08438-0openalex-snapshot
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inferred← citeshttps://doi.org/10.1038/s41598-022-22256-3openalex-snapshot
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Naphthomycin-derived macrolactams with two new carbon skeletons from endophytic Streptomyces
inferred← citeshttps://doi.org/10.1039/c9nj01619hopenalex-snapshot
Actinobacteria associated with stingless bees biosynthesize bioactive polyketides against bacterial pathogens
inferred← citeshttps://doi.org/10.1039/d1np00022eopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/d1np00044fopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/d1qo00610jopenalex-snapshot
Revised structural assignment of azalomycins based on genomic and chemical analysis
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Structural diversity and biological relevance of benzenoid and atypical ansamycins and their congeners
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Bacterial marginolactones trigger formation of algal gloeocapsoids, protective aggregates on the verge of multicellularity
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A new spectinabilin derivative with cytotoxic activity from ant-derived Streptomyces sp. 1H-GS5
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inferred← citeshttps://doi.org/10.1093/ismeco/ycae094openalex-snapshot
Non-ribosomal peptide synthase profiles remain structurally similar despite minimally shared features across fungus-farming termite microbiomes
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Genome mining for drug discovery: cyclic lipopeptides related to daptomycin
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Ubiquitous bacterial polyketides induce cross-kingdom microbial interactions
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Dynamic environments of fungus‐farming termite mounds exert growth‐modulating effects on fungal crop parasites
inferred← citeshttps://doi.org/10.1111/1744-7917.12799openalex-snapshot
Diversity of fungal isolates from fungus‐growing termite Macrotermes barneyi and characterization of bioactive compound from Xylaria escharoidea
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Community structure and antifungal activity of actinobacteria in a fungus‐growing termite
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Fungus-farming termites can protect their crop by confining weeds with fungistatic soil boluses
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Red Soils Harbor Diverse Culturable Actinomycetes That Are Promising Sources of Novel Secondary Metabolites
inferred← citeshttps://doi.org/10.1128/mbio.02781-21openalex-snapshot
Habitat Adaptation Drives Speciation of a Streptomyces Species with Distinct Habitats and Disparate Geographic Origins
inferred← citeshttps://doi.org/10.1128/msphere.01233-20openalex-snapshot
Comparative Genomics Reveals Prophylactic and Catabolic Capabilities of Actinobacteria within the Fungus-Farming Termite Symbiosis
inferred← citeshttps://doi.org/10.1146/annurev-micro-012420-081224openalex-snapshot
Chemical Mediators at the Bacterial-Fungal Interface
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Antimicrobial Production by an Actinomycetes Isolated from The Termite Nest
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inferred← citeshttps://doi.org/10.1177/1934578x241250236openalex-snapshot
Studies Toward the Total Synthesis of Natalamycin A: Stereoselective Synthesis of the C9–C21 Segment
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Pseudomonas Can Prevent the Parasitic Fungus, While Keeping the Crop Fungus Unaffected, in the Gardens of Odontotermes Obesus.
inferred← citeshttps://doi.org/10.21203/rs.3.rs-26431/v1openalex-snapshot
Antibacterial Potential of Streptomyces showdoensis BYC17 from the Nest of Odontotermes formosanus
inferred← citeshttps://doi.org/10.2174/0929867328666210806114949openalex-snapshot
A Comparative Insight on the Newly Emerging Rifamycins: Rifametane, Rifalazil, TNP-2092 and TNP-2198
inferred← citeshttps://doi.org/10.3389/fmicb.2019.01739openalex-snapshot
Efomycins K and L From a Termite-Associated Streptomyces sp. M56 and Their Putative Biosynthetic Origin
inferred← citeshttps://doi.org/10.3389/fmicb.2021.632637openalex-snapshot
Pollen Streptomyces Produce Antibiotic That Inhibits the Honey Bee Pathogen Paenibacillus larvae
inferred← citeshttps://doi.org/10.3389/fmicb.2021.649962openalex-snapshot
Polyene-Producing Streptomyces spp. From the Fungus-Growing Termite Macrotermes barneyi Exhibit High Inhibitory Activity Against the Antagonistic Fungus Xylaria
inferred← citeshttps://doi.org/10.3389/fmicb.2022.1061603openalex-snapshot
Antifungal metabolites, their novel sources, and targets to combat drug resistance
inferred← citeshttps://doi.org/10.3390/antibiotics10060621openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/antibiotics7020044openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/antibiotics7030083openalex-snapshot
Natural Products from Actinobacteria Associated with Fungus-Growing Termites
inferred← citeshttps://doi.org/10.3390/antibiotics9080494openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms19010174openalex-snapshot
Chemical Characterization of a Renoprotective Metabolite from Termite-Associated Streptomyces sp. RB1 against Cisplatin-Induced Cytotoxicity
inferred← citeshttps://doi.org/10.3390/ijms19092640openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms25010537openalex-snapshot
Animal Microbiomes as a Source of Novel Antibiotic-Producing Strains
inferred← citeshttps://doi.org/10.3390/insects14090741openalex-snapshot
Symbiotic Bacteria Regulating Insect–Insect/Fungus/Virus Mutualism
inferred← citeshttps://doi.org/10.3390/microorganisms8091390openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/molecules22050707openalex-snapshot
Sampling Terrestrial Environments for Bacterial Polyketides
inferred← citeshttps://doi.org/10.3390/molecules23102568openalex-snapshot
The Inhibitory Effects of Cyclodepsipeptides from the Entomopathogenic Fungus Beauveria bassiana on Myofibroblast Differentiation in A549 Alveolar Epithelial Cells
inferred← citeshttps://doi.org/10.3390/molecules23113003openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/molecules28114276openalex-snapshot
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inferred← citeshttps://doi.org/10.3762/bjoc.12.34openalex-snapshot
Natural products from microbes associated with insects
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ANTIFUNGAL ACTIVITY OF TWO STREPTOMYCES SPECIES ISOLATED FROM EGYPTIAN SOIL AGAINST SOME PHYTOPATHOGENIC FUNGI
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Streptomyces as a Source of Antimicrobials: Novel Approaches to Activate Cryptic Secondary Metabolite Pathways
inferred← citeshttps://doi.org/10.58837/chula.the.2020.34openalex-snapshot
Effects of valproic acid on fatty acid production in microorganisms and bioactive compounds from feroniella lucida (scheff.) Swingle and termite-associated fungus ISFB10
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