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Exosome isolation: a microfluidic road-map

https://doi.org/10.1039/c5lc00240k
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s10544-014-9891-zopenalex-snapshot
Microfluidic isolation of cancer-cell-derived microvesicles from hetergeneous extracellular shed vesicle populations
inferredcites →https://doi.org/10.1016/j.addr.2012.08.008openalex-snapshot
Exosomes for targeted siRNA delivery across biological barriers
inferredcites →https://doi.org/10.1016/j.bios.2012.12.046openalex-snapshot
Detection of exosomal biomarker by electric field-induced release and measurement (EFIRM)
inferredcites →https://doi.org/10.1016/j.ceb.2014.05.004openalex-snapshot
Biogenesis and secretion of exosomes
inferredcites →https://doi.org/10.1016/j.toxlet.2014.01.013openalex-snapshot
Circulating extracellular vesicles as a potential source of new biomarkers of drug-induced liver injury
inferredcites →https://doi.org/10.1016/j.ymeth.2012.01.002openalex-snapshot
Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes
inferredcites →https://doi.org/10.1016/s0022-1759(02)00330-7openalex-snapshot
Production and characterization of clinical grade exosomes derived from dendritic cells
inferredcites →https://doi.org/10.1016/s0022-2275(20)41889-9openalex-snapshot
Quantitative measurement of lipoprotein surface charge by agarose gel electrophoresis.
inferredcites →https://doi.org/10.1021/ac502082bopenalex-snapshot
Detecting Exosomes Specifically: A Multiplexed Device Based on Alternating Current Electrohydrodynamic Induced Nanoshearing
inferredcites →https://doi.org/10.1021/nn405016yopenalex-snapshot
Magnetic Nanosensor for Detection and Profiling of Erythrocyte-Derived Microvesicles
inferredcites →https://doi.org/10.1038/nbt.1807openalex-snapshot
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
inferredcites →https://doi.org/10.1038/nbt.2886openalex-snapshot
Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor
inferredcites →https://doi.org/10.1038/ncb1596openalex-snapshot
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
inferredcites →https://doi.org/10.1038/ncb1800openalex-snapshot
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
inferredcites →https://doi.org/10.1038/nm.2994openalex-snapshot
Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy
inferredcites →https://doi.org/10.1038/sj.ki.5000273openalex-snapshot
Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery
inferredcites →https://doi.org/10.1039/b916199fopenalex-snapshot
Microfluidic isolation and transcriptome analysis of serum microvesicles
inferredcites →https://doi.org/10.1039/c2lc41006kopenalex-snapshot
Microfluidic filtration system to isolate extracellular vesicles from blood
inferredcites →https://doi.org/10.1039/c3lc41343hopenalex-snapshot
Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles
inferredcites →https://doi.org/10.1039/c4lc00136bopenalex-snapshot
Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes
inferredcites →https://doi.org/10.1039/c4lc00662copenalex-snapshot
Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology
inferredcites →https://doi.org/10.1039/c5lc00036jopenalex-snapshot
On-chip surface acoustic wave lysis and ion-exchange nanomembrane detection of exosomal RNA for pancreatic cancer study and diagnosis
inferredcites →https://doi.org/10.1063/1.4907807openalex-snapshot
Rapid inertial solution exchange for enrichment and flow cytometric detection of microvesicles
inferredcites →https://doi.org/10.1073/pnas.0403453101openalex-snapshot
Identification and proteomic profiling of exosomes in human urine
inferredcites →https://doi.org/10.1073/pnas.1220998110openalex-snapshot
Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
inferredcites →https://doi.org/10.1093/nar/gkr1079openalex-snapshot
NCBI Reference Sequences (RefSeq): current status, new features and genome annotation policy
inferredcites →https://doi.org/10.1093/nar/gks463openalex-snapshot
Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes
inferredcites →https://doi.org/10.1113/jphysiol.2013.264069openalex-snapshot
Quantification of human urinary exosomes by nanoparticle tracking analysis
inferredcites →https://doi.org/10.1124/pr.112.005983openalex-snapshot
Classification, Functions, and Clinical Relevance of Extracellular Vesicles
inferredcites →https://doi.org/10.1371/journal.pone.0030679openalex-snapshot
The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes
inferredcites →https://doi.org/10.1515/hsz-2013-0141openalex-snapshot
Current methods for the isolation of extracellular vesicles
inferredcites →https://doi.org/10.1681/asn.2013101066openalex-snapshot
Human Urinary Exosomes as Innate Immune Effectors
inferredcites →https://doi.org/10.3402/jev.v1i0.18396openalex-snapshot
Cellular stress conditions are reflected in the protein and RNA content of endothelial cell‐derived exosomes
inferredcites →https://doi.org/10.3402/jev.v2i0.20360openalex-snapshot
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
inferredcites →https://doi.org/10.3402/jev.v3.23743openalex-snapshot
Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell‐free blood
inferredcites →https://doi.org/10.3402/jev.v3.24858openalex-snapshot
The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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THE PRESENT AND FUTURE OF THE MASS SPECTROMETRY‐BASED INVESTIGATION OF THE EXOSOME LANDSCAPE
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In Situ Monitoring of the Movement of a Single Nanovesicle: Toward Elucidating Their Biological Activities in Human Cells
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Laser‐Patterning of Micromagnets for Immuno‐Magnetophoretic Exosome Capture
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Potential of on‐chip analysis and engineering techniques for extracellular vesicle bioproduction for therapeutics
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The Future Prospects in Effective Management of Glioblastoma Multiforme Using Exosomes: A Comprehensive Review
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Extracellular Vesicle Biomarkers for Renal Diseases
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Current and emerging molecular diagnostic approaches in the detection of human parasites
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Latest developments in advanced exosome engineering for optimized site-specific drug delivery by modulating exosome functionalities in breast cancer
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Engineered exosome nanocarriers for targeted cardiovascular therapy
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Diagnostic Potential of Tumor Exosomes
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Urine Exosomes
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Exosomes isolated from two different cell lines using three different isolation techniques show variation in physical and molecular characteristics
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Emerging technologies and commercial products in exosome-based cancer diagnosis and prognosis
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Electrochemical nano-sensing interface for exosomes analysis and cancer diagnosis
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Surface plasmon resonance: A promising approach for label-free early cancer diagnosis
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Molecular markers in cancer
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Extracellular Vesicles Move Toward Use in Clinical Laboratories
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Recent advances on extracellular vesicles in therapeutic delivery: Challenges, solutions, and opportunities
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An overview of challenges associated with exosomal miRNA isolation toward liquid biopsy-based ovarian cancer detection
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New insight into isolation, identification techniques and medical applications of exosomes
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Emerging prospects of extracellular vesicles for brain disease theranostics
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Plant-derived extracellular vesicles as oral drug delivery carriers
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Exosomes as next-generation drug carriers: Transforming cancer therapy
inferred← citeshttps://doi.org/10.1016/j.jddst.2021.103057openalex-snapshot
Exosomes and exosome-mimetics as targeted drug carriers: Where we stand and what the future holds?
inferred← citeshttps://doi.org/10.1016/j.jddst.2024.105618openalex-snapshot
Plant-derived extracellular vesicles as potential smart nano drug delivery systems for antioxidant vitamins C and E in Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.jid.2017.04.021openalex-snapshot
Extracellular Vesicles as Biomarkers and Therapeutics in Dermatology: A Focus on Exosomes
inferred← citeshttps://doi.org/10.1016/j.jtos.2025.05.001openalex-snapshot
Tear fluid derived extracellular vesicles for new biomarker discovery
inferred← citeshttps://doi.org/10.1016/j.matpr.2019.03.162openalex-snapshot
Dielectrophoretic manipulation of exosomes in a multi-section microfluidic device
inferred← citeshttps://doi.org/10.1016/j.mcn.2024.103982openalex-snapshot
Microfluidics in neural extracellular vesicles characterization for early Alzheimer's disease diagnosis
inferred← citeshttps://doi.org/10.1016/j.mee.2019.111094openalex-snapshot
Isolation and detection of exosomes via AAO membrane and QCM measurement
inferred← citeshttps://doi.org/10.1016/j.mtbio.2022.100371openalex-snapshot
Nanomaterials assisted exosomes isolation and analysis towards liquid biopsy
inferred← citeshttps://doi.org/10.1016/j.mtbio.2023.100556openalex-snapshot
Exosomes and ultrasound: The future of theranostic applications
inferred← citeshttps://doi.org/10.1016/j.mtnano.2021.100148openalex-snapshot
Converting extracellular vesicles into nanomedicine: loading and unloading of cargo
inferred← citeshttps://doi.org/10.1016/j.nano.2017.10.008openalex-snapshot
Exosome function in aerodigestive mucosa
inferred← citeshttps://doi.org/10.1016/j.nantod.2020.100964openalex-snapshot
Efficient encapsulation of biocompatible nanoparticles in exosomes for cancer theranostics
inferred← citeshttps://doi.org/10.1016/j.nantod.2020.101066openalex-snapshot
Towards microfluidic-based exosome isolation and detection for tumor therapy
inferred← citeshttps://doi.org/10.1016/j.nantod.2024.102169openalex-snapshot
The landscape of extracellular vesicles combined with intranasal delivery towards brain diseases
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2023.09.001openalex-snapshot
The Biology, Pathological Roles of Exosomes and Their Clinical Application in Parkinson’s Disease
inferred← citeshttps://doi.org/10.1016/j.omtn.2017.11.014openalex-snapshot
Exosomes in Cancer Liquid Biopsy: A Focus on Breast Cancer
inferred← citeshttps://doi.org/10.1016/j.omtn.2021.11.027openalex-snapshot
RETRACTED: Promotion of tumor progression by exosome transmission of circular RNA circSKA3
inferred← citeshttps://doi.org/10.1016/j.pdpdt.2026.105370openalex-snapshot
Milk-derived exosomes (MDE) for photosensitizer delivery in photodynamic therapy: A review
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2018.08.002openalex-snapshot
Extracellular vesicles and their nucleic acids for biomarker discovery
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2024.108754openalex-snapshot
The pharmacodynamic and pharmacological mechanisms underlying nanovesicles of natural products: Developments and challenges
inferred← citeshttps://doi.org/10.1016/j.phymed.2025.157104openalex-snapshot
Advances of Chinese medicine-derived exosomes in disease intervention and drug delivery system
inferred← citeshttps://doi.org/10.1016/j.prp.2025.155950openalex-snapshot
Exosomes in melanoma: Future potential for clinical theranostics
inferred← citeshttps://doi.org/10.1016/j.smaim.2021.06.001openalex-snapshot
Recent advances of emerging microfluidic chips for exosome mediated cancer diagnosis
inferred← citeshttps://doi.org/10.1016/j.snb.2016.04.091openalex-snapshot
Isolation of extracellular vesicle from blood plasma using electrophoretic migration through porous membrane
inferred← citeshttps://doi.org/10.1016/j.snb.2021.129559openalex-snapshot
Rapid exosomes concentration and in situ detection of exosomal microRNA on agarose-based microfluidic chip
inferred← citeshttps://doi.org/10.1016/j.snb.2022.133193openalex-snapshot
Self-directed molecular diagnostics (SdMDx) system for COVID-19 via one-pot processing
inferred← citeshttps://doi.org/10.1016/j.talanta.2021.122870openalex-snapshot
ExoPRIME: Solid-phase immunoisolation and OMICS analysis of surface-marker-specific exosomal subpopulations
inferred← citeshttps://doi.org/10.1016/j.theriogenology.2023.09.026openalex-snapshot
The effects of boar seminal plasma extracellular vesicles on sperm fertility
inferred← citeshttps://doi.org/10.1016/j.thromres.2020.09.020openalex-snapshot
A new hybrid immunocapture bioassay with improved reproducibility to measure tissue factor-dependent procoagulant activity of microvesicles from body fluids
inferred← citeshttps://doi.org/10.1016/j.tibtech.2020.05.012openalex-snapshot
Technologies and Standardization in Research on Extracellular Vesicles
inferred← citeshttps://doi.org/10.1016/j.tice.2025.103068openalex-snapshot
Unlocking the potential of EXOs in regenerative medicine: A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.trac.2018.07.014openalex-snapshot
Characterization and applications of extracellular vesicle proteome with post-translational modifications
inferred← citeshttps://doi.org/10.1016/j.trac.2021.116179openalex-snapshot
Recent electrokinetic strategies for isolation, enrichment and separation of extracellular vesicles
inferred← citeshttps://doi.org/10.1016/j.trac.2022.116840openalex-snapshot
Recent advances in exosomal RNAs analysis towards diagnostic and therapeutic applications
inferred← citeshttps://doi.org/10.1016/j.trac.2022.116912openalex-snapshot
Recent advances in microfluidic approaches for the isolation and detection of exosomes
inferred← citeshttps://doi.org/10.1016/j.trac.2026.118915openalex-snapshot
Plant-derived exosome-like nanovesicles: Recent advances in isolation technologies and neurodegenerative applications
inferred← citeshttps://doi.org/10.1016/j.tranon.2022.101439openalex-snapshot
Exosomes: Insights and therapeutic applications in cancer
inferred← citeshttps://doi.org/10.1016/j.trsl.2018.05.007openalex-snapshot
Molecular assessment of circulating exosomes toward liquid biopsy diagnosis of Ewing sarcoma family of tumors
inferred← citeshttps://doi.org/10.1021/acs.analchem.0c04152openalex-snapshot
Circulating Tumor Marker Isolation with the Chemically Stable and Instantly Degradable (CSID) Hydrogel ImmunoSpheres
inferred← citeshttps://doi.org/10.1021/acs.analchem.3c02224openalex-snapshot
Exploring the Versatility of Exosomes: A Review on Isolation, Characterization, Detection Methods, and Diverse Applications
inferred← citeshttps://doi.org/10.1021/acs.analchem.3c03303openalex-snapshot
Enhancing Extracellular Vesicle Analysis by Integration of Large-Volume Sample Stacking in Capillary Electrophoresis with Asymmetrical Flow Field-Flow Fractionation
inferred← citeshttps://doi.org/10.1021/acs.analchem.4c06172openalex-snapshot
Digital Lasing Biochip for Tumor-Derived Exosome Analysis
inferred← citeshttps://doi.org/10.1021/acs.analchem.5b04532openalex-snapshot
Cellular Analysis Using Microfluidics
inferred← citeshttps://doi.org/10.1021/acs.analchem.5c02003openalex-snapshot
Sensitive Detection of Exosomal Biomarkers via a Drop-Shaped Porous Microfluidic Chip for Potential Diagnosis of Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1021/acs.analchem.6b05037openalex-snapshot
Concentration-Normalized Electroanalytical Assaying of Exosomal Markers
inferred← citeshttps://doi.org/10.1021/acs.analchem.7b04861openalex-snapshot
Highly Efficient Exosome Isolation and Protein Analysis by an Integrated Nanomaterial-Based Platform
inferred← citeshttps://doi.org/10.1021/acs.analchem.8b01187openalex-snapshot
Quantification of Exosome Based on a Copper-Mediated Signal Amplification Strategy
inferred← citeshttps://doi.org/10.1021/acs.analchem.8b03031openalex-snapshot
Isolation and Visible Detection of Tumor-Derived Exosomes from Plasma
inferred← citeshttps://doi.org/10.1021/acs.analchem.9b03448openalex-snapshot
Electrokinetically Driven Exosome Separation and Concentration Using Dielectrophoretic-Enhanced PDMS-Based Microfluidics
inferred← citeshttps://doi.org/10.1021/acs.nanolett.0c00950openalex-snapshot
Immunoavidity-Based Capture of Tumor Exosomes Using Poly(amidoamine) Dendrimer Surfaces
inferred← citeshttps://doi.org/10.1021/acs.nanolett.0c02558openalex-snapshot
Nanofluidics for Simultaneous Size and Charge Profiling of Extracellular Vesicles
inferred← citeshttps://doi.org/10.1021/acsami.7b06464openalex-snapshot
Chemically Edited Exosomes with Dual Ligand Purified by Microfluidic Device for Active Targeted Drug Delivery to Tumor Cells
inferred← citeshttps://doi.org/10.1021/acsami.9b20990openalex-snapshot
Rapid Size-Based Isolation of Extracellular Vesicles by Three-Dimensional Carbon Nanotube Arrays
inferred← citeshttps://doi.org/10.1021/acsanm.3c04537openalex-snapshot
Synergizing Proteolysis-Targeting Chimeras and Nanoscale Exosome-Based Delivery Mechanisms for HIV and Antiviral Therapeutics
inferred← citeshttps://doi.org/10.1021/acsanm.8b00267openalex-snapshot
Review: Isolation and Detection of Tumor-Derived Extracellular Vesicles
inferred← citeshttps://doi.org/10.1021/acsnano.2c04337openalex-snapshot
Future of Digital Assays to Resolve Clinical Heterogeneity of Single Extracellular Vesicles
inferred← citeshttps://doi.org/10.1021/acsnano.7b02277openalex-snapshot
Field-Free Isolation of Exosomes from Extracellular Vesicles by Microfluidic Viscoelastic Flows
inferred← citeshttps://doi.org/10.1021/acsnano.7b04878openalex-snapshot
The Exosome Total Isolation Chip
inferred← citeshttps://doi.org/10.1021/acsnano.9b06459openalex-snapshot
Nanophotonic Array-Induced Dynamic Behavior for Label-Free Shape-Selective Bacteria Sieving
inferred← citeshttps://doi.org/10.1021/acsomega.8b00033openalex-snapshot
Enhanced Optical Collection of Micro- and Nanovesicles in the Presence of Gold Nanoparticles
inferred← citeshttps://doi.org/10.1038/nnano.2016.134openalex-snapshot
Nanoscale lateral displacement arrays for the separation of exosomes and colloids down to 20 nm
inferred← citeshttps://doi.org/10.1038/nrc.2017.83openalex-snapshot
Engineering and physical sciences in oncology: challenges and opportunities
inferred← citeshttps://doi.org/10.1038/nrgastro.2017.71openalex-snapshot
Extracellular vesicles in liver disease and potential as biomarkers and therapeutic targets
inferred← citeshttps://doi.org/10.1038/s41368-025-00370-yopenalex-snapshot
Isolation methods of exosomes derived from dental stem cells
inferred← citeshttps://doi.org/10.1038/s41392-024-02021-wopenalex-snapshot
Liquid biopsy in cancer: current status, challenges and future prospects
inferred← citeshttps://doi.org/10.1038/s41392-025-02312-wopenalex-snapshot
Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies
inferred← citeshttps://doi.org/10.1038/s41413-020-0100-9openalex-snapshot
Exosomes: roles and therapeutic potential in osteoarthritis
inferred← citeshttps://doi.org/10.1038/s41440-025-02109-yopenalex-snapshot
Clinical studies in Myxomatous Mitral Valve Disease dogs: most prescribed ACEI inhibits ACE2 enzyme activity and ARB increases AngII pool in plasma
inferred← citeshttps://doi.org/10.1038/s41551-017-0058openalex-snapshot
Rapid magnetic isolation of extracellular vesicles via lipid-based nanoprobes
inferred← citeshttps://doi.org/10.1038/s41551-017-0061openalex-snapshot
Cancer diagnostics: Extracting extracellular vesicles
inferred← citeshttps://doi.org/10.1038/s41585-022-00660-8openalex-snapshot
Microfluidics facilitating the use of small extracellular vesicles in innovative approaches to male infertility
inferred← citeshttps://doi.org/10.1038/s41598-017-08826-wopenalex-snapshot
Separation of extracellular nanovesicles and apoptotic bodies from cancer cell culture broth using tunable microfluidic systems
inferred← citeshttps://doi.org/10.1038/s41598-020-65995-xopenalex-snapshot
Design and Fabrication of Low-cost Microfluidic Channel for Biomedical Application
inferred← citeshttps://doi.org/10.1038/s41598-021-86910-yopenalex-snapshot
Immunomagnetic sequential ultrafiltration (iSUF) platform for enrichment and purification of extracellular vesicles from biofluids
inferred← citeshttps://doi.org/10.1038/s41598-024-65209-8openalex-snapshot
Differential extracellular vesicle concentration and their biomarker expression of integrin αv/β5, EpCAM, and glypican-1 in pancreatic cancer models
inferred← citeshttps://doi.org/10.1039/c5an01762aopenalex-snapshot
Isolation and enrichment of circulating biomarkers for cancer screening, detection, and diagnostics
showing the first 200 of 380
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