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Three-component reactions of isocyanoacetates, amines and 3-formylchromones initiated by an unexpected aza-Michael addition

https://doi.org/10.1039/c7cc03468g
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/anie.200460548openalex-snapshot
Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
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Pyrrole Syntheses by Multicomponent Coupling Reactions
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Versatile Direct Synthesis of Oligosubstituted Pyrroles by Cycloaddition of α‐Metalated Isocyanides to Acetylenes
inferredcites →https://doi.org/10.1002/anie.200605005openalex-snapshot
Modulating the Reactivity of α‐Isocyanoacetates: Multicomponent Synthesis of 5‐Methoxyoxazoles and Furopyrrolones
inferredcites →https://doi.org/10.1002/anie.200902385openalex-snapshot
Brønsted Acid Catalyzed Enantioselective Three‐Component Reaction Involving the α Addition of Isocyanides to Imines
inferredcites →https://doi.org/10.1002/anie.201302024openalex-snapshot
Silver‐Catalyzed Isocyanide‐Alkyne Cycloaddition: A General and Practical Method to Oligosubstituted Pyrroles
inferredcites →https://doi.org/10.1002/anie.201302604openalex-snapshot
Synthesis of Pyrroles by Click Reaction: Silver‐Catalyzed Cycloaddition of Terminal Alkynes with Isocyanides
inferredcites →https://doi.org/10.1002/anie.201309719openalex-snapshot
Direct Catalytic Enantio‐ and Diastereoselective Mannich Reaction of Isocyanoacetates and Ketimines
inferredcites →https://doi.org/10.1002/anie.201402788openalex-snapshot
Highly Diastereo‐ and Enantioselective Silver‐Catalyzed Double [3+2] Cyclization of α‐Imino Esters with Isocyanoacetate
inferredcites →https://doi.org/10.1002/anie.201404629openalex-snapshot
Direct Asymmetric Mannich‐Type Reaction of α‐Isocyanoacetates with Ketimines using Cinchona Alkaloid/Copper(II) Catalysts
inferredcites →https://doi.org/10.1002/cctc.201200135openalex-snapshot
Advances and Applications in Organocatalytic Asymmetric aza‐Michael Addition
inferredcites →https://doi.org/10.1002/chem.200800271openalex-snapshot
Selective Formation of 2‐Imidazolines and 2‐Substituted Oxazoles by Using a Three‐Component Reaction
inferredcites →https://doi.org/10.1002/chem.200802140openalex-snapshot
Applications of Multicomponent Reactions to the Synthesis of Diverse Heterocyclic Scaffolds
inferredcites →https://doi.org/10.1002/chem.200902236openalex-snapshot
Organocatalytic Asymmetric Aza‐Michael Additions
inferredcites →https://doi.org/10.1002/chem.201002098openalex-snapshot
Exploiting the Divergent Reactivity of α‐Isocyanoacetate: Multicomponent Synthesis of 5‐Alkoxyoxazoles and Related Heterocycles
inferredcites →https://doi.org/10.1002/chem.201202174openalex-snapshot
Organocatalytic Enantioselective One‐Pot Four‐Component Ugi‐Type Multicomponent Reaction for the Synthesis of Epoxy‐tetrahydropyrrolo[3,4‐b]pyridin‐5‐ones
inferredcites →https://doi.org/10.1002/chin.200405056openalex-snapshot
Novel Multicomponent Reaction for the Combinatorial Synthesis of 2‐Imidazolines.
inferredcites →https://doi.org/10.1002/jhet.5570450601openalex-snapshot
Chemistry and application of 4‐oxo‐4H‐1‐benzopyran‐3‐carboxaldehyde
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The M06 suite of density functionals for main group thermochemistry, thermochemical kinetics, noncovalent interactions, excited states, and transition elements: two new functionals and systematic testing of four M06-class functionals and 12 other functionals
inferredcites →https://doi.org/10.1016/j.dyepig.2016.03.016openalex-snapshot
Improved synthesis dimethylhomoecoerdianthrone (HOCD) and its functionalization through facile amination reactions
inferredcites →https://doi.org/10.1016/j.tet.2012.01.077openalex-snapshot
Recyclizations of 3-formylchromones with binucleophiles
inferredcites →https://doi.org/10.1016/j.tet.2014.06.124openalex-snapshot
Uncatalyzed, green aza-Michael addition of amines to dimethyl maleate
inferredcites →https://doi.org/10.1016/j.tetasy.2005.08.033openalex-snapshot
Amination/annulation of chlorobutenones with chiral amine compounds: synthesis of 1,2,4-trisubstituted pyrroles
inferredcites →https://doi.org/10.1016/j.tetasy.2008.07.027openalex-snapshot
Chiral palladium-pincer complex catalyzed asymmetric condensation of sulfonimines and isocyanoacetate
inferredcites →https://doi.org/10.1016/j.tetasy.2010.04.029openalex-snapshot
Organocatalytic asymmetric Mannich-type reaction of N-sulfonylimines with isocyanoacetate leading to optically active 2-imidazoline-4-carboxylates
inferredcites →https://doi.org/10.1016/j.tetlet.2016.11.005openalex-snapshot
Silver-catalyzed organic reactions of isocyanides
inferredcites →https://doi.org/10.1016/s0040-4020(01)89069-4openalex-snapshot
A useful synthesis of pyrroles from nitroolefins
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A general synthesis of 2-substituted-5-aminooxazoles: building blocks for multifunctional heterocycles
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In Silico Design of Halogen-Bonding-Based Organocatalyst for Diels–Alder Reaction, Claisen Rearrangement, and Cope-Type Hydroamination
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Brønsted-Acid-Catalyzed Asymmetric Multicomponent Reactions for the Facile Synthesis of Highly Enantioenriched Structurally Diverse Nitrogenous Heterocycles
inferredcites →https://doi.org/10.1021/cr020095iopenalex-snapshot
Transition-Metal-Catalyzed Reactions in Heterocyclic Synthesis
inferredcites →https://doi.org/10.1021/cr0505728openalex-snapshot
Recent Developments in Isocyanide Based Multicomponent Reactions in Applied Chemistry
inferredcites →https://doi.org/10.1021/cr900411fopenalex-snapshot
Isocyanoacetate Derivatives: Synthesis, Reactivity, and Application
inferredcites →https://doi.org/10.1021/ja051875mopenalex-snapshot
Copper- or Phosphine-Catalyzed Reaction of Alkynes with Isocyanides. Regioselective Synthesis of Substituted Pyrroles Controlled by the Catalyst
inferredcites →https://doi.org/10.1021/ja4005893openalex-snapshot
Oxyanion Hole Stabilization by C–H···O Interaction in a Transition State—A Three-Point Interaction Model for Cinchona Alkaloid-Catalyzed Asymmetric Methanolysis of meso -Cyclic Anhydrides
inferredcites →https://doi.org/10.1021/ja511895qopenalex-snapshot
Catalytic Divergent Synthesis of 3H or 1H Pyrroles by [3 + 2] Cyclization of Allenoates with Activated Isocyanides
inferredcites →https://doi.org/10.1021/jm030990+openalex-snapshot
3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 2. Effect of Pyrrole-C2 and/or -C4 Substitutions on Biological Activity
inferredcites →https://doi.org/10.1021/jo050132gopenalex-snapshot
Multicomponent Synthesis of 2-Imidazolines
inferredcites →https://doi.org/10.1021/jo070840xopenalex-snapshot
A Resource-Efficient and Highly Flexible Procedure for a Three-Component Synthesis of 2-Imidazolines
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Understanding α,β-Unsaturated Imine Formation from Amine Additions to α,β-Unsaturated Aldehydes and Ketones: An Analytical and Theoretical Investigation
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An Investigation of Imidazole and Oxazole Syntheses Using Aryl-Substituted TosMIC Reagents1
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Universal Solvation Model Based on Solute Electron Density and on a Continuum Model of the Solvent Defined by the Bulk Dielectric Constant and Atomic Surface Tensions
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Annulation Reactions of Allene-Derived 1,3-Dipole with 3-Substituted-Chromones: Unusual Recognition of 4π-Component in 3-(N-Aryliminomethyl)chromones through [4 + 3] Annulation
inferredcites →https://doi.org/10.1021/ol007055qopenalex-snapshot
A Novel Multicomponent Synthesis of Polysubstituted 5-Aminooxazole and Its New Scaffold-Generating Reaction to Pyrrolo[3,4-b]pyridine
inferredcites →https://doi.org/10.1021/ol035521gopenalex-snapshot
Novel Multicomponent Reaction for the Combinatorial Synthesis of 2-Imidazolines
inferredcites →https://doi.org/10.1021/ol061782popenalex-snapshot
One-Pot Synthesis of Macrocycles by a Tandem Three-Component Reaction and Intramolecular [3+2] Cycloaddition
inferredcites →https://doi.org/10.1021/ol102826fopenalex-snapshot
Copper-Catalyzed Tandem Reactions of 1-(2-Iodoary)-2-yn-1-ones with Isocyanides for the Synthesis of 4-Oxo-indeno[1,2-b]pyrroles
inferredcites →https://doi.org/10.1021/ol202708fopenalex-snapshot
An Efficient Route to Tetrahydroindeno[2,1-b]pyrroles via a Base-Promoted Reaction of (E)-2-Alkynylphenylchalcone with 2-Isocyanoacetate
inferredcites →https://doi.org/10.1021/ol301256qopenalex-snapshot
Enantioselective Synthesis of Imidazolines with Quaternary Stereocenters by Organocatalytic Reaction of N-(Heteroarenesulfonyl)imines with Isocyanoacetates
inferredcites →https://doi.org/10.1021/ol502123zopenalex-snapshot
Cinchona Alkaloid Squaramide/AgOAc Cooperatively Catalyzed Diastereo- and Enantioselective Mannich/Cyclization Cascade Reaction of Isocyanoacetates and Cyclic Trifluoromethyl Ketimines
inferredcites →https://doi.org/10.1021/om070168uopenalex-snapshot
Multicomponent Synthesis of N-Heterocyclic Carbene Complexes
inferredcites →https://doi.org/10.1039/b917644fopenalex-snapshot
Multicomponent reactions for the synthesis of pyrroles
inferredcites →https://doi.org/10.1039/c0cc00500bopenalex-snapshot
Domino allylic amination/Sonogashira/heterocyclisation reactions: palladium-catalysed three-component synthesis of pyrroles
inferredcites →https://doi.org/10.1039/c3ra44595jopenalex-snapshot
Copper-catalyzed synthesis of 1,2,4-trisubstituted pyrroles via cascade reactions of aryloxy-enynes with amines
inferredcites →https://doi.org/10.1039/c6cc02911fopenalex-snapshot
Enantioselective construction of imidazolines having vicinal tetra-substituted stereocenters by direct Mannich reaction of α-substituted α-isocyanoacetates with ketimines
inferredcites →https://doi.org/10.1039/c6qo00555aopenalex-snapshot
Formal [3 + 2] cycloaddition of α-unsubstituted isocyanoacetates and methyleneindolinones: enantioselective synthesis of spirooxindoles
inferredcites →https://doi.org/10.1039/p19870001995openalex-snapshot
Studies on chromone derivatives. Novel 1,3 dipolar cycloadditions of 4-oxo-1-benzopyran-3-carbaldehyde imines and imine oxides
inferredcites →https://doi.org/10.3390/10080937openalex-snapshot
Reactions of 3-Formylchromone with Active Methylene and Methyl Compounds and Some Subsequent Reactions of the Resulting Condensation Products
inferredcites →https://doi.org/10.7164/antibiotics.56.931openalex-snapshot
Bhimamycin A-E and Bhimanone: Isolation, Structure Elucidation and Biological Activity of Novel Quinone Antibiotics from a Terrestrial Streptomycete

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4651066openalex-extracted
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inferred← citeshttps://doi.org/10.1002/9783527832439.ch1openalex-snapshot
Heterocycles as Inputs in MCRs : An Update
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Metal‐Free N‐Annulation of 3‐Formylchromones with α‐Amino Ketones for the Construction of Diverse N‐Functionalized Pyrroles
inferred← citeshttps://doi.org/10.1002/ajoc.202200448openalex-snapshot
Efficient Synthesis of Pyrazoles by pH Dependent Isomerization of Enaminodiones
inferred← citeshttps://doi.org/10.1002/ange.202202679openalex-snapshot
Diastereo‐ and Enantioselective Silver‐Catalyzed [3+3] Cycloaddition and Kinetic Resolution of Azomethine Imines with Activated Isocyanides
inferred← citeshttps://doi.org/10.1002/anie.202202679openalex-snapshot
Diastereo‐ and Enantioselective Silver‐Catalyzed [3+3] Cycloaddition and Kinetic Resolution of Azomethine Imines with Activated Isocyanides
inferred← citeshttps://doi.org/10.1002/app.52747openalex-snapshot
Self‐dispersible waterborne comb‐like polyester with alkali resistance and pigment‐dispersion capability
inferred← citeshttps://doi.org/10.1002/chem.201801768openalex-snapshot
Divergent, Enantioselective Synthesis of Pyrroles, 3 H ‐Pyrroles and Bicyclic Imidazolines by Ag‐ or P‐Catalyzed [3+2] Cycloaddition of Allenoates with Activated Isocyanides
inferred← citeshttps://doi.org/10.1002/ejoc.202000890openalex-snapshot
Recent Advances in the Chemistry of Isocyanides with Activated Methylene Group
inferred← citeshttps://doi.org/10.1002/ejoc.202001460openalex-snapshot
Silver‐Catalyzed Acyl Nitrene Transfer Reactions Involving Dioxazolones: Direct Assembly of N‐Acylureas
inferred← citeshttps://doi.org/10.1007/s11030-023-10625-7openalex-snapshot
Copper-catalyzed C2-selective alkynylation of chromones via 1,4-conjugate addition
inferred← citeshttps://doi.org/10.1016/b978-0-12-818584-1.00003-3openalex-snapshot
Synthesis of heterocycles via MCRs, using a name reaction in combination with another reaction
inferred← citeshttps://doi.org/10.1016/bs.aihch.2023.04.004openalex-snapshot
Recent advances in the synthesis of five-membered heterocycles via multicomponent and domino reactions (from 2017 to 2022)
inferred← citeshttps://doi.org/10.1016/j.gresc.2022.05.002openalex-snapshot
Multicomponent cascade reaction of 3-formylchromones: Highly regioselective synthesis of functionalized pyridin-2(1H)-ones
inferred← citeshttps://doi.org/10.1016/j.gresc.2022.10.003openalex-snapshot
Cascade reaction of 3-formylchromones: Highly selective synthesis of 4-oxo-3-(1H-pyrrol-3-yl)-4H-chromenes
inferred← citeshttps://doi.org/10.1016/j.gresc.2022.10.014openalex-snapshot
Highly selective synthesis of functionalized morphan derivatives through a multi-component cascade reaction of 3-formylchromones, 2-naphthols, and enaminones
inferred← citeshttps://doi.org/10.1021/acs.joc.1c02434openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.joc.2c00695openalex-snapshot
An Environmentally Benign Multicomponent Cascade Reaction of 3-Formylchromones, 2-Naphthols, and Heterocyclic Ketal Aminals: Site-Selective Synthesis of Functionalized Morphan Derivatives
inferred← citeshttps://doi.org/10.1021/acs.joc.2c01719openalex-snapshot
Multicomponent Cascade Reaction of 3-Cyanochromones: Highly Site-Selective Synthesis of 2-(1H-Imidazol-1-yl)-4H-chromen-4-one Derivatives
inferred← citeshttps://doi.org/10.1021/acs.joc.8b00099openalex-snapshot
Three-Component Site-Selective Synthesis of Highly Substituted 5H-Chromeno-[4,3-b]pyridines
inferred← citeshttps://doi.org/10.1021/acs.orglett.1c01632openalex-snapshot
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Multicomponent Cascade Reaction of 3-Formylchromones: Highly Selective Synthesis of Functionalized 9-Azabicyclo[3.3.1]nonane Derivatives
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inferred← citeshttps://doi.org/10.1021/acs.orglett.8b01948openalex-snapshot
Cu-Catalyzed [3 + 3] Cycloaddition of Isocyanoacetates with Aziridines and Stereoselective Access to α,γ-Diamino Acids
inferred← citeshttps://doi.org/10.1021/acs.orglett.8b02383openalex-snapshot
Enantioselective Silver-Catalyzed Cascade Synthesis of Fused Lactone and Lactam Oxazolines
inferred← citeshttps://doi.org/10.1039/c7ob02933kopenalex-snapshot
An approach towards the synthesis of novel fused nitrogen tricyclic heterocyclic scaffolds via GBB reaction
inferred← citeshttps://doi.org/10.1039/c7qo00692fopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/c8ob01558aopenalex-snapshot
Transition-metal-free synthesis of polysubstituted pyrrole derivatives via cyclization of methyl isocyanoacetate with aurone analogues
inferred← citeshttps://doi.org/10.1039/c8ob03034kopenalex-snapshot
Recent advances in the asymmetric synthesis of pharmacology-relevant nitrogen heterocycles via stereoselective aza-Michael reactions
inferred← citeshttps://doi.org/10.1039/c9qo01044kopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/c9ra06778gopenalex-snapshot
Transition metal-free one-pot synthesis of substituted pyrroles by employing aza-Wittig reaction
inferred← citeshttps://doi.org/10.1039/d0nj02315aopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/d1cc02437jopenalex-snapshot
Multi-component cascade reaction of 3-formylchromones: highly selective synthesis of 4,5-dihydro-[4,5′-bipyrimidin]-6(1 H )-one derivatives
inferred← citeshttps://doi.org/10.1039/d1nj04514hopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/d2cc01625gopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/d2cc03816aopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/d2gc01689copenalex-snapshot
Practical synthesis of quinolone drugs via a novel TsCl-mediated domino reaction sequence
inferred← citeshttps://doi.org/10.1039/d3qo00524kopenalex-snapshot
Cu-catalyzed decarboxylative annulation of proline derivatives: multi-component synthesis of functionalized chromeno[2,3- c ]-pyrrol-9(1 H )-one derivatives
inferred← citeshttps://doi.org/10.1039/d4nj01648copenalex-snapshot
Cu( ii )-catalyzed annulation of α,β-unsaturated ketoxime acetates with 3-formylchromones for the synthesis of functionalized 2,4-diarylpyridines
inferred← citeshttps://doi.org/10.1039/d5nj03333kopenalex-snapshot
Silver or copper-catalyzed ring opening [3+2] annulation of 2-polyfluoroalkyl chromones/6-polyfluoroalkyl pyran-4 H -ones with methylene isocyanides: regioselective synthesis of 3-polyfluoroalkyl pyrroles
inferred← citeshttps://doi.org/10.1039/d6qo00608fopenalex-snapshot
Unexpected products in isocyanide-based multicomponent reactions
inferred← citeshttps://doi.org/10.1055/a-1681-7480openalex-snapshot
Iron-Catalyzed One-Pot Synthesis of Indole-Tethered Tetrasubstituted Pyrroles and Their Transformations to Indolizino[8,7-b]indole Derivatives
inferred← citeshttps://doi.org/10.1055/a-1904-0582openalex-snapshot
Catalytic Asymmetric [3+3] Cycloaddition of Activated Isocyanides with Azomethine Imines
inferred← citeshttps://doi.org/10.2174/1385272826666220610162605openalex-snapshot
Asymmetric Synthesis: A Glance at Various Methodologies for Different Frameworks
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