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Protective effects of sesamol on systemic oxidative stress-induced cognitive impairments via regulation of Nrf2/Keap1 pathway

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jnr.10749openalex-snapshot

Protective effects of sesamin and sesamolin on hypoxic neuronal and PC12 cells

inferredcites →https://doi.org/10.1002/jnr.20770openalex-snapshot

Inhibition of nociceptive responses of spinal cord neurones during hypertension involves the spinal GABAergic system and a pain modulatory center located at the caudal ventrolateral medulla

inferredcites →https://doi.org/10.1002/jnr.20845openalex-snapshot

Chronic systemic D‐galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: Protective effects of R‐α‐lipoic acid

inferredcites →https://doi.org/10.1002/jnr.20899openalex-snapshot

Chronic systemic D ‐galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: Protective effects of R‐α‐lipoic acid

inferredcites →https://doi.org/10.1002/mnfr.201600734openalex-snapshot

Sesamol supplementation prevents systemic inflammation‐induced memory impairment and amyloidogenesis via inhibition of nuclear factor kappaB

inferredcites →https://doi.org/10.1006/nbdi.2002.0515openalex-snapshot

Oxidative Stress Increases Expression and Activity of BACE in NT2 Neurons

inferredcites →https://doi.org/10.1007/978-1-4020-6051-9_17openalex-snapshot

Peroxiredoxins in the Central Nervous System

inferredcites →https://doi.org/10.1007/s00394-012-0482-6openalex-snapshot

Attenuation of adjuvant-induced arthritis by dietary sesamol via modulation of inflammatory mediators, extracellular matrix degrading enzymes and antioxidant status

inferredcites →https://doi.org/10.1007/s11746-011-1994-6openalex-snapshot

Structural Effect of Lignans and Sesamol on Polymerization of Soybean Oil at Frying Temperature

inferredcites →https://doi.org/10.1007/s11746-013-2204-5openalex-snapshot

Antioxidant Activity of Sesamol in Soybean Oil Under Frying Conditions

inferredcites →https://doi.org/10.1007/s12035-015-9604-5openalex-snapshot

Anthocyanins Reversed D-Galactose-Induced Oxidative Stress and Neuroinflammation Mediated Cognitive Impairment in Adult Rats

inferredcites →https://doi.org/10.1007/s12551-016-0244-4openalex-snapshot

The Keap1–Nrf2 pathway: promising therapeutic target to counteract ROS-mediated damage in cancers and neurodegenerative diseases

inferredcites →https://doi.org/10.1016/j.bbadis.2015.03.015openalex-snapshot

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

inferredcites →https://doi.org/10.1016/j.bbamcr.2015.01.017openalex-snapshot

Metformin increases APP expression and processing via oxidative stress, mitochondrial dysfunction and NF-κB activation: Use of insulin to attenuate metformin's effect

inferredcites →https://doi.org/10.1016/j.bbr.2004.07.003openalex-snapshot

Behavioural study of the -galactose induced aging model in C57BL/6J mice

inferredcites →https://doi.org/10.1016/j.bcp.2008.07.017openalex-snapshot

Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis

inferredcites →https://doi.org/10.1016/j.biopha.2003.11.004openalex-snapshot

Neurodegenerative diseases and oxidative stress

inferredcites →https://doi.org/10.1016/j.biopsych.2008.07.024openalex-snapshot

Systemic Inflammation Induces Acute Behavioral and Cognitive Changes and Accelerates Neurodegenerative Disease

inferredcites →https://doi.org/10.1016/j.brainres.2010.09.052openalex-snapshot

Neuroprotective effect of osthole against acute ischemic stroke on middle cerebral ischemia occlusion in rats

inferredcites →https://doi.org/10.1016/j.ejphar.2014.11.014openalex-snapshot

Neuroprotective potential of sesamol and its loaded solid lipid nanoparticles in ICV-STZ-induced cognitive deficits: Behavioral and biochemical evidence

inferredcites →https://doi.org/10.1016/j.fct.2008.12.005openalex-snapshot

Purple sweet potato color attenuates oxidative stress and inflammatory response induced by d-galactose in mouse liver

inferredcites →https://doi.org/10.1016/j.fct.2017.01.022openalex-snapshot

Protective effects of rambutan (Nephelium lappaceum) peel phenolics on H2O2-induced oxidative damages in HepG2 cells and d-galactose-induced aging mice

inferredcites →https://doi.org/10.1016/j.fct.2017.09.050openalex-snapshot

Supplementation of lycopene attenuates oxidative stress induced neuroinflammation and cognitive impairment via Nrf2/NF-κB transcriptional pathway

inferredcites →https://doi.org/10.1016/j.freeradbiomed.2008.09.001openalex-snapshot

Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease?

inferredcites →https://doi.org/10.1016/j.jff.2017.02.003openalex-snapshot

High-accuracy mass spectrometry for identification of sulphur-containing bioactive constituents and flavonoids in extracts of Raphanus sativus var. caudatus Alef (Thai rat-tailed radish)

inferredcites →https://doi.org/10.1016/j.jff.2018.01.005openalex-snapshot

Extract of sesame cake and sesamol alleviate chronic unpredictable mild stress-induced depressive-like behaviors and memory deficits

inferredcites →https://doi.org/10.1016/j.nbd.2009.06.003openalex-snapshot

Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice

inferredcites →https://doi.org/10.1016/j.neulet.2004.06.077openalex-snapshot

APP and PS-1 mutations induce brain oxidative stress independent of dietary cholesterol: implications for Alzheimer’s disease

inferredcites →https://doi.org/10.1016/j.pbb.2015.03.020openalex-snapshot

Fibroblast growth factor 21 protects mouse brain against d-galactose induced aging via suppression of oxidative stress response and advanced glycation end products formation

inferredcites →https://doi.org/10.1016/s0047-6374(99)00022-6openalex-snapshot

Advanced glycation in d-galactose induced mouse aging model

inferredcites →https://doi.org/10.1016/s0197-4580(02)00019-2openalex-snapshot

Oxidative stress in brain agingImplications for therapeutics of neurodegenerative diseases

inferredcites →https://doi.org/10.1021/acs.jafc.6b01237openalex-snapshot

Effects of Sesaminol Feeding on Brain Aβ Accumulation in a Senescence-Accelerated Mouse-Prone 8

inferredcites →https://doi.org/10.1021/jf8012647openalex-snapshot

Bioavailability and Tissue Distribution of Sesamol in Rat

inferredcites →https://doi.org/10.1038/nature05292openalex-snapshot

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

inferredcites →https://doi.org/10.1038/nrd1330openalex-snapshot

Neurodegenerative diseases and oxidative stress

inferredcites →https://doi.org/10.1039/c6fo01562jopenalex-snapshot

Sesamol ameliorates high-fat and high-fructose induced cognitive defects via improving insulin signaling disruption in the central nervous system

inferredcites →https://doi.org/10.1039/c7ra06325copenalex-snapshot

Chicoric acid supplementation ameliorates cognitive impairment induced by oxidative stress via promotion of antioxidant defense system

inferredcites →https://doi.org/10.1046/j.1365-277x.1997.00488.xopenalex-snapshot

Natural antioxidants and food quality in atherosclerosis and cancer prevention

inferredcites →https://doi.org/10.1073/pnas.0305799101openalex-snapshot

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

inferredcites →https://doi.org/10.1073/pnas.0908397106openalex-snapshot

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease

inferredcites →https://doi.org/10.1074/jbc.r900010200openalex-snapshot

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

inferredcites →https://doi.org/10.1080/03602530600971974openalex-snapshot

Mechanistic Studies of the Nrf2-Keap1 Signaling Pathway

inferredcites →https://doi.org/10.1089/ars.2010.3567openalex-snapshot

CNS Peroxiredoxins and Their Regulation in Health and Disease

inferredcites →https://doi.org/10.1093/jn/128.6.1018openalex-snapshot

Sesamolin Inhibits Lipid Peroxidation in Rat Liver and Kidney

inferredcites →https://doi.org/10.1111/j.1742-7843.2010.00537.xopenalex-snapshot

Protective Effect of Sesamol against 3‐Nitropropionic Acid‐Induced Cognitive Dysfunction and Altered Glutathione Redox Balance in Rats

inferredcites →https://doi.org/10.1126/science.7901908openalex-snapshot

Oxidative Stress, Glutamate, and Neurodegenerative Disorders

inferredcites →https://doi.org/10.1186/1742-2094-8-57openalex-snapshot

Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation

inferredcites →https://doi.org/10.1371/journal.pone.0088562openalex-snapshot

Hippocampal Neurochemical Changes in Senescent Mice Induced with Chronic Injection of D-Galactose and NaNO2: An In Vitro High-Resolution NMR Spectroscopy Study at 9.4T

inferredcites →https://doi.org/10.2174/138161210793176572openalex-snapshot

Neuroinflammation, Oxidative Stress and the Pathogenesis of Alzheimers Disease

inferredcites →https://doi.org/10.2174/157340609788681476openalex-snapshot

Sesamol: An Efficient Antioxidant with Potential Therapeutic Benefits

inferredcites →https://doi.org/10.2174/1871520613666131224123346openalex-snapshot

Sesamol Ameliorates Cyclophosphamide-Induced Hepatotoxicity by Modulating Oxidative Stress and Inflammatory Mediators

inferredcites →https://doi.org/10.22159/ijpps.2016v8i12.14529openalex-snapshot

SESAMOL ANTAGONIZES ROTENONE-INDUCED CELL DEATH IN SH-SY5Y NEURONAL CELLS

inferredcites →https://doi.org/10.3892/etm.2017.4550openalex-snapshot

Sesamol attenuates oxidative stress, apoptosis and inflammation in focal cerebral ischemia/reperfusion injury

inferredcites →https://doi.org/10.4172/2168-9296.1000e122openalex-snapshot

Rise and Fall of Reactive Oxygen Species (ROS): Implications in Aging and Neurodegenerative Disorders

inferredcites →https://doi.org/10.5603/fhc.a2015.0034openalex-snapshot

Effects of rosmarinic acid on cognitive and biochemical alterations in ovariectomized rats treated with D-galactose

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Gastrodia elata Polysaccharide Attenuates Aging by Modulating Oxidative Stress, Inflammation, and Gut Microbiota

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Sesamol Alleviated Lipotoxicity‐Induced Dysfunction in MIN6 Cells via Facilitating Cellular Senescence Caused by Endoplasmic Reticulum Stress

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Preventive Effects of Sesamol on Deep‐Frying Oil‐Induced Liver Metabolism Disorders by Altering Gut Microbiota and Protecting Gut Barrier Integrity

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Sesamol Mitigates Chronic Iron Overload‐Induced Cognitive Impairment and Systemic Inflammation via IL‐6 and DMT1 Regulation

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Sesamol as a multifunctional antioxidant in tissue injury and repair: mechanistic insights and therapeutic perspectives

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Sesamol prevents mitochondrial impairment and pro-inflammatory alterations in the human neuroblastoma SH-SY5Y cells: role for Nrf2

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A computational study to identify Sesamol derivatives as NRF2 activator for protection against drug-induced liver injury (DILI)

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Neuroprotective effect of sesamol against aluminum nanoparticle-induced toxicity in rats

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In Silico Analysis to Link Insulin Resistance, Obesity and Ageing with Alzheimer’s Disease

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Nrf2 Signaling Pathway: a Potential Therapeutic Target in Combating Oxidative Stress and Neurotoxicity in Chemotherapy-Induced Cognitive Impairment

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Advanced drug delivery systems to treat Huntington’s disease: challenges and opportunities

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Natural compounds as an alternative to counteract the neurotoxic effects of quinolinic acid

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Sesamol as a potential small molecule in inhibiting the induction of neurotoxic amyloids fibrils involved in the pathophysiology of alzheimer's disease

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Targeting the Nrf2/HO-1 aixs: A therapeutic strategy against regulated cell death in Alzheimer’s disease

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Harnessing role of sesamol and its nanoformulations against neurodegenerative diseases

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Preventive effects of pomegranate seed oil on transient middle cerebral artery occlusion via the Keap1/Nrf2/NQO1 pathway in the rats cortex

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Sulforaphane improves cognitive dysfunction after surgery and anesthesia in mice: The role of Keap1-Nrf2 signaling

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Roles of homopolymeric apoferritin in alleviating alcohol-induced liver injury

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Food and nutraceutical functions of sesame oil: An underutilized crop for nutritional and health benefits

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Sesame oil mitigates memory impairment, oxidative stress, and neurodegeneration in a rat model of Alzheimer's disease. A pivotal role of NF-κB/p38MAPK/BDNF/PPAR-γ pathways

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Neuroprotection of round scad (Decapterus maruadsi) hydrolysate in glutamate-damaged PC12 cells: Possible involved signaling pathways and potential bioactive peptides

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Recent advances and possibilities for the use of plant phenolic compounds to manage ageing-related diseases

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Ferroptosis: An important mechanism of disease mediated by the gut-liver-brain axis

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Targeting the Nrf2 signaling pathway using phytochemical ingredients: A novel therapeutic road map to combat neurodegenerative diseases

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Sesamol as a potential candidate for the treatment of hepatic fibrosis, based on its regulation of FXR/LXR axis-mediated inhibition of autophagy through crosstalk between hepatic cells and macrophage

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Protective Effects of Sesamol on Renal Ischemia-Reperfusion Injury Via Regulation of Nuclear Factor Erythroid 2-Related Factor 2 Pathway

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Sea-Buckthorn Flavonoids Alleviate High-Fat and High-Fructose Diet-Induced Cognitive Impairment by Inhibiting Insulin Resistance and Neuroinflammation

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Sea Cucumber-Derived Peptide Attenuates Scopolamine-Induced Cognitive Impairment by Preventing Hippocampal Cholinergic Dysfunction and Neuronal Cell Death

inferred← citeshttps://doi.org/10.1021/acs.jafc.2c04292openalex-snapshot

Sesamol Attenuates Scopolamine-Induced Cholinergic Disorders, Neuroinflammation, and Cognitive Deficits in Mice

inferred← citeshttps://doi.org/10.1021/acs.jafc.4c06106openalex-snapshot

Supplementation of 3′-Sialyllactose During the Growth Period Improves Learning and Memory Development in Mice

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ApoE-Dependent Protective Effects of Sesamol on High-Fat Diet-Induced Behavioral Disorders: Regulation of the Microbiome-Gut–Brain Axis

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Protective Effects of Sesamol on Systemic Inflammation and Cognitive Impairment in Aging Mice

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Computationally Designed Sesamol Derivatives Proposed as Potent Antioxidants

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Parapyruvate Induces Neurodegeneration in C57BL/6JNarl Mice via Inhibition of the α-Ketoglutarate Dehydrogenase Complex

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Sesamol supplementation alleviates nonalcoholic steatohepatitis and atherosclerosis in high-fat, high carbohydrate and high-cholesterol diet-fed rats

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Crateva unilocularis Buch. shoots attenuate d -galactose-induced brain injury and cognitive disorders of mice through the PI3K/Akt/Nrf2 pathway

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Sesamol ameliorates dextran sulfate sodium-induced depression-like and anxiety-like behaviors in colitis mice: the potential involvement of the gut–brain axis

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Lycopene attenuates d -galactose-induced insulin signaling impairment by enhancing mitochondrial function and suppressing the oxidative stress/inflammatory response in mouse kidneys and livers

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Quercetin modulates the liver metabolic profile in a chronic unpredictable mild stress rat model based on metabolomics technology

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A novel neuroprotective peptide YVYAETY identified and screened from Flammulina velutipes protein hydrolysates attenuates scopolamine-induced cognitive impairment in mice

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Sesamol alleviates chronic intermittent hypoxia-induced cognitive deficits via inhibiting oxidative stress and inflammation in rats

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Icaritin activates Nrf2/Keap1 signaling to protect neuronal cells from oxidative stress

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Icaritin inhibits oxidative stress in murine astrocytes by binding to Orai1 to block store‐operated calcium channel

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Alginate oligosaccharide alleviates D‐galactose‐induced cardiac ageing via regulating myocardial mitochondria function and integrity in mice

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Sesamol protects the function and structure of rat ovaries against side effects of cyclophosphamide by decreasing oxidative stress and apoptosis

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Sesamol Protects Testis from Ischemia-Reperfusion Injury through Scavenging Reactive Oxygen Species and Upregulating CREM τ Expression

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Sesamol Attenuates Neuroinflammation by Regulating the AMPK/SIRT1/NF‐ κ B Signaling Pathway after Spinal Cord Injury in Mice

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Immunomodulation in Multiple Sclerosis by Phytotherapy

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Effect of sesamol on damaged peripheral nerves: Evaluation of functional, histological, molecular, and oxidative stress parameters.

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Neuroprotective effects of sesamol against LPS-induced spatial learning and memory deficits are mediated via anti-inflammatory and antioxidant activities in the rat brain.

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Sesamol promotes browning of white adipocytes to ameliorate obesity by inducing mitochondrial biogenesis and inhibition mitophagy via β3-AR/PKA signaling pathway

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Mechanism analysis and intervention strategies of the inflammatory microenvironment in traumatic spinal cord injury

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Suk-SaiYasna Remedy, a Traditional Thai Medicine, Mitigates Stress-Induced Cognitive Impairment via Keap1-Nrf2 Pathway

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Sesamol Increases Ucp1 Expression in White Adipose Tissues and Stimulates Energy Expenditure in High-Fat Diet-Fed Obese Mice

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Protective Effects of Sesamol against Liver Oxidative Stress and Inflammation in High-Fat Diet-Induced Hepatic Steatosis

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Characterization and Exploration of the Neuroprotective Potential of Oat-Protein-Derived Peptides in PC12 Cells and Scopolamine-Treated Zebrafish

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Sesamol Loaded Albumin Nanoparticles: A Boosted Protective Property in Animal Models of Oxidative Stress

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