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Health functions and structure–activity relationships of natural anthraquinones from plants
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/0891-5849(93)90012-jopenalex-snapshotPhotosensitization with anticancer agents 17. EPR studies of photodynamic action of hypericin: Formation of semiquinone radical and activated oxygen species on illumination
inferredcites →https://doi.org/10.1016/j.bmc.2006.02.036openalex-snapshotEffects of structural modification on the DNA binding properties and photo-induced cleavage reactivity of propargylic sulfones conjugated with an anthraquinone structure
inferredcites →https://doi.org/10.1016/j.jep.2016.06.037openalex-snapshotInhibitory activities of major anthraquinones and other constituents from Cassia obtusifolia against β-secretase and cholinesterases
inferredcites →https://doi.org/10.1016/j.phymed.2009.10.009openalex-snapshotMicrocalorimetric assay on the antimicrobial property of five hydroxyanthraquinone derivatives in rhubarb (Rheum palmatum L.) to Bifidobacterium adolescentis
inferredcites →https://doi.org/10.1016/j.ultsonch.2013.08.023openalex-snapshotComparisons between conventional, ultrasound-assisted and microwave-assisted methods for extraction of anthraquinones from Heterophyllaea pustulata Hook f. (Rubiaceae)
inferredcites →https://doi.org/10.1021/jf0489116openalex-snapshotAntioxidant Phenolic Constituents in Roots of Rheum officinale and Rubia cordifolia: Structure−Radical Scavenging Activity Relationships
inferredcites →https://doi.org/10.1021/np50123a005openalex-snapshotEffect of Anthraquinone Derivatives on Lipid Peroxidation in Rat Heart Mitochondria: Structure-Activity Relationship
inferredcites →https://doi.org/10.1021/tx100248sopenalex-snapshotDanthron, an Anthraquinone Derivative, Induces DNA Damage and Caspase Cascades-Mediated Apoptosis in SNU-1 Human Gastric Cancer Cells through Mitochondrial Permeability Transition Pores and Bax-Triggered Pathways
inferredcites →https://doi.org/10.1038/srep19267openalex-snapshotCalcium-chelating alizarin and other anthraquinones inhibit biofilm formation and the hemolytic activity of Staphylococcus aureus
inferredcites →https://doi.org/10.1080/14786419.2016.1160234openalex-snapshotPrisconnatanones A, a cytotoxic naphthoquinone from Prismatomeris connata, suppresses the proliferation of human laryngocarcinoma HEp-2 cells in vitro
inferredcites →https://doi.org/10.1159/000484120openalex-snapshotAloe-Emodin Relieves High-Fat Diet Induced QT Prolongation via MiR-1 Inhibition and IK1 Up-Regulation in Rats
inferredcites →https://doi.org/10.1186/s13071-017-2338-7openalex-snapshotNatural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana
inferredcites →https://doi.org/10.12659/msm.907163openalex-snapshotQuinalizarin Induces Apoptosis through Reactive Oxygen Species (ROS)-Mediated Mitogen-Activated Protein Kinase (MAPK) and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathways in Colorectal Cancer Cells
inferredcites →https://doi.org/10.1371/journal.pone.0027480openalex-snapshotCombined Phytochemistry and Chemotaxis Assays for Identification and Mechanistic Analysis of Anti-Inflammatory Phytochemicals in Fallopia japonica
inferredcites →https://doi.org/10.3390/ijms13022276openalex-snapshotEmodin Prevents Intrahepatic Fat Accumulation, Inflammation and Redox Status Imbalance During Diet-Induced Hepatosteatosis in Rats
inferredcites →https://doi.org/10.3390/md14040064openalex-snapshotAnthraquinones and Derivatives from Marine-Derived Fungi: Structural Diversity and Selected Biological Activities
inferredcites →https://doi.org/10.3390/molecules22020265openalex-snapshotStructure-Antioxidative and Anti-Inflammatory Activity Relationships of Purpurin and Related Anthraquinones in Chemical and Cell Assays
inferredcites →https://doi.org/10.3892/ol.2017.5915openalex-snapshotThe effect of aloe-emodin-induced photodynamic activity on the apoptosis of human gastric cancer cells: A pilot study
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4777267openalex-extractedThe Synergistic Effect of Titanium Dioxide with Aloe Vera and Apple Extract on Poly(Butylene Adipate-Co-Terephthalate) Biocomposites Films for Extended Shelf-Life of Banana
inferred← citeshttps://doi.org/10.1002/cbic.202400953openalex-snapshotRevealing the Monooxygenase Mechanism for Selective Ring Cleavage of Anthraquinone by BTG13 through Multiscale Simulations
inferred← citeshttps://doi.org/10.1002/ps.8177openalex-snapshotIsolation of anthraquinone derivatives from Rubia cordifolia (Rubiaceae) and their bioactivities against plant pathogenic microorganisms
inferred← citeshttps://doi.org/10.1002/slct.73819openalex-snapshotPotential Utilization of Natural Anthraquinone Aglycone Emodin for Alzheimer's Disease: A Comprehensive Review With Computational Insights
inferred← citeshttps://doi.org/10.1007/s00289-025-05782-8openalex-snapshotThe synergistic effect of titanium dioxide with aloe vera and apple extract on poly(butylene adipate-co-terephthalate) biocomposite films for extended shelf life of banana
inferred← citeshttps://doi.org/10.1007/s00894-024-05848-wopenalex-snapshotPossible NLO response and electrical/charge transfer capabilities of natural anthraquinones as p-type organic semiconductors: a DFT approach
inferred← citeshttps://doi.org/10.1007/s10787-023-01295-wopenalex-snapshotRhein methotrexate-decorated solid lipid nanoparticles altering adjuvant arthritis progression through endoplasmic reticulum stress-mediated apoptosis
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2023.108104openalex-snapshotRecent advances in the identification of biosynthetic genes and gene clusters of the polyketide-derived pathways for anthraquinone biosynthesis and biotechnological applications
inferred← citeshttps://doi.org/10.1016/j.fbio.2025.107831openalex-snapshotAnti-microbial activities of anthraquinones from Aspergillus cristatus derived from Fuzhuan brick tea against pathogenic bacteria via cell membrane disruption and genomic DNA binding
inferred← citeshttps://doi.org/10.1016/j.fct.2023.113802openalex-snapshotInduction of Nrf2-EpRE-mediated gene expression by hydroxyanthraquinones present in extracts from traditional Chinese medicine and herbs
inferred← citeshttps://doi.org/10.1016/j.foodchem.2021.130730openalex-snapshotColor-reflected chemical regulations of the scorched rhubarb (Rhei Radix et Rhizoma) revealed by the integration analysis of visible spectrophotometry, Fourier transform infrared spectroscopy and high performance liquid chromatography
inferred← citeshttps://doi.org/10.1016/j.insi.2026.100570openalex-snapshotIn silico prioritization of Cinchona officinalis-derived compounds against selected influenza and human parainfluenza viral targets: Molecular docking, MM-GBSA, DFT, and molecular dynamics simulation studies
inferred← citeshttps://doi.org/10.1016/j.intimp.2020.106936openalex-snapshotEmodin 8-O-glucoside primes macrophages more strongly than emodin aglycone via activation of phagocytic activity and TLR-2/MAPK/NF-κB signalling pathway
inferred← citeshttps://doi.org/10.1016/j.jep.2020.112861openalex-snapshotAqueous extraction from dachengqi formula granules reduces the severity of mouse acute pancreatitis via inhibition of pancreatic pro-inflammatory signalling pathways
inferred← citeshttps://doi.org/10.1016/j.jep.2021.113845openalex-snapshotExploration of components and mechanisms of Polygoni Multiflori Radix-induced hepatotoxicity using siRNA -mediated CYP3A4 or UGT1A1 knockdown liver cells
inferred← citeshttps://doi.org/10.1016/j.jpba.2023.115846openalex-snapshotSynergistic and attenuated effects and molecular biological mechanisms of Shouhui Tongbian capsule in the treatment of slow transit constipation based on UPLC-MS/MS, network pharmacology and animal experimental validation
inferred← citeshttps://doi.org/10.1016/j.lfs.2021.120131openalex-snapshotQuinizarin suppresses the differentiation of adipocytes and lipogenesis in vitro and in vivo via downregulation of C/EBP-beta/SREBP pathway
inferred← citeshttps://doi.org/10.1016/j.lfs.2022.120495openalex-snapshotAloe emodin 3-O-glucoside inhibits cell growth and migration and induces apoptosis of non-small-cell lung cancer cells via suppressing MEK/ERK and Akt signalling pathways
inferred← citeshttps://doi.org/10.1016/j.molstruc.2020.128307openalex-snapshotCascading chemical transitions of rhubarb (Rhei Radix et Rhizoma) during the scorching process revealed by heated ATR-FTIR spectroscopy and two-dimensional correlation analysis
inferred← citeshttps://doi.org/10.1016/j.prenap.2025.100414openalex-snapshotUnlocking the anticancer potential of Morinda citrifolia-derived anthraquinones: Preclinical evidence and molecular mechanisms in colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.saa.2022.120853openalex-snapshotTwo-dimensional correlation spectroscopy indicates the infrared spectral markers of the optimum scorching degree of rhubarb (Rhei Radix et Rhizoma) to enhance the anti-inflammatory activity
inferred← citeshttps://doi.org/10.1021/acs.jafc.3c00345openalex-snapshotAnthraquinone Removal from Cassia obtusifolia Seed Water Extract Using Baking, Stir-Frying, and Adsorption Treatments: Effects on the Chemical Composition, Physicochemical Properties of Polysaccharides, and Antioxidant Activities of the Water Extract
inferred← citeshttps://doi.org/10.1021/acsomega.3c03656openalex-snapshotUHPLC-QQQ-MS and RP-HPLC Detection of Bioactive Alizarin and Scopoletin Metabolites from Morinda citrifolia Root Extracts and Their Antitubercular, Antibacterial, and Antioxidant Activities
inferred← citeshttps://doi.org/10.1039/d0md00315hopenalex-snapshotDesign, synthesis, and biological evaluation of pyrazole-linked aloe emodin derivatives as potential anticancer agents
inferred← citeshttps://doi.org/10.1039/d0ra06414aopenalex-snapshot2-Bromoanthraquinone as a highly efficient photocatalyst for the oxidation of sec -aromatic alcohols: experimental and DFT study
inferred← citeshttps://doi.org/10.1039/d1dt00952dopenalex-snapshotAutocatalytic photodegradation of [Ru( ii )(2,2′-bipyridine) 2 DAD] + (DADH = 1,2-dihydroxyanthracene-9,10-dione) by hydrogen peroxide under acidic aqueous conditions
inferred← citeshttps://doi.org/10.1101/862029openalex-snapshotPhylobioactive hotspots identified through multidimensional profiling of botanical drugs used to treat Chagas disease in Bolivia and Dioscorides’ De Materia Medica
inferred← citeshttps://doi.org/10.1111/cbdd.14062openalex-snapshotSynergy between machine learning and natural products cheminformatics: Application to the lead discovery of anthraquinone derivatives
inferred← citeshttps://doi.org/10.1142/s0219519423500252openalex-snapshotA NETWORK PHARMACOLOGICAL INVESTIGATION INTO THE TREATMENT OF PERIMENOPAUSAL DEPRESSION WITH A WARMING AND TONIFYING KIDNEY-YANG RECIPE
inferred← citeshttps://doi.org/10.1177/00405175231167603openalex-snapshotFunctionalization of silk with chitosan and Rubia cordifolia L. dye extract for enhanced antimicrobial and ultraviolet protective properties
inferred← citeshttps://doi.org/10.1186/s12864-021-07658-3openalex-snapshotTissue-specific transcriptome analyses reveal candidate genes for stilbene, flavonoid and anthraquinone biosynthesis in the medicinal plant Polygonum cuspidatum
inferred← citeshttps://doi.org/10.14295/bjs.v3i11.694openalex-snapshotPhytochemical screening, phenolic and flavonoid contents, psilocybin, antioxidant, and acetylcholinesterase inhibition activities of the aqueous extract from the fungi Cyathus striatus, Laternea dringii, and Marasmius haematocephalus
inferred← citeshttps://doi.org/10.2147/dddt.s439633openalex-snapshotSynthesis of a New Series of Anthraquinone-Linked Cyclopentanone Derivatives: Investigating the Antioxidant, Antibacterial, Cytotoxic and Tyrosinase Inhibitory Activities of the Mushroom Tyrosinase Enzyme Using Molecular Docking
inferred← citeshttps://doi.org/10.3389/fmicb.2024.1393073openalex-snapshotUtilization of carbon catabolite repression for efficiently biotransformation of anthraquinone O-glucuronides by Streptomyces coeruleorubidus DM
inferred← citeshttps://doi.org/10.3389/fphar.2026.1844144openalex-snapshotHallachrome, a marine anthraquinone, impairs cell proliferation by acting as a functional mitochondrial uncoupler in A375 melanoma cells
inferred← citeshttps://doi.org/10.3390/agronomy12061295openalex-snapshotSimultaneous Estimation of Rhein and Aloe-Emodin in Traditional and Ultrasound-Based Extracts of Rheum palmatum L. (Rhubarb) Using Sustainable Reverse-Phase and Conventional Normal-Phase HPTLC Methods
inferred← citeshttps://doi.org/10.3390/antiox11020311openalex-snapshotVariability of Phenolic Compound Accumulation and Antioxidant Activity in Wild Plants of Some Rumex Species (Polygonaceae)
inferred← citeshttps://doi.org/10.3390/foods12091781openalex-snapshotFresh and Browned Lotus Root Extracts Promote Cholesterol Metabolism in FFA-Induced HepG2 Cells through Different Pathways
inferred← citeshttps://doi.org/10.3390/ijms23031694openalex-snapshotBacterial Inoculant and Sucrose Amendments Improve the Growth of Rheum palmatum L. by Reprograming Its Metabolite Composition and Altering Its Soil Microbial Community
inferred← citeshttps://doi.org/10.3390/molecules29010203openalex-snapshotIn Silico and In Vitro Identification of 1,8-Dihydroxy-4,5-dinitroanthraquinone as a New Antibacterial Agent against Staphylococcus aureus and Enterococcus faecalis
inferred← citeshttps://doi.org/10.3390/toxics10030142openalex-snapshotAnthraquinones: Genotoxic until Proven Otherwise? A Study on a Substance-Based Medical Device to Implement Available Data for a Correct Risk Assessment
inferred← citeshttps://doi.org/10.35516/jjps.v17i4.2448openalex-snapshotRumex conglomeratus Murr. Grown Wild in Syria: Phytochemical Analysis and in Vitro Antioxidant Activities of Aerial Parts and Rhizomes Extracts
inferred← citeshttps://doi.org/10.48130/mpb-0025-0020openalex-snapshotProfiling the accumulation of ten bioactive compounds in Rheum officinale across different growth years using integrated HPLC and transcriptomic approaches
inferred← citeshttps://doi.org/10.6084/m9.figshare.14609069openalex-snapshotAdditional file 1 of Tissue-specific transcriptome analyses reveal candidate genes for stilbene, flavonoid and anthraquinone biosynthesis in the medicinal plant Polygonum cuspidatum
inferred← citeshttps://doi.org/10.6084/m9.figshare.14609072openalex-snapshotAdditional file 2 of Tissue-specific transcriptome analyses reveal candidate genes for stilbene, flavonoid and anthraquinone biosynthesis in the medicinal plant Polygonum cuspidatum
inferred← citeshttps://doi.org/10.6084/m9.figshare.14609075openalex-snapshotAdditional file 3 of Tissue-specific transcriptome analyses reveal candidate genes for stilbene, flavonoid and anthraquinone biosynthesis in the medicinal plant Polygonum cuspidatum
inferred← citeshttps://doi.org/10.7783/kjmcs.2026.34.1.12openalex-snapshotAttenuating Effect of Geijigadaehwang-tang in Aggression Animal Model by Isolation Rearing Based on Experimental Study and Network Pharmacology
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