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Development of a method for the quantitative metabolite profiling of pharmaceutical drugs using HPLC-ICP-MS following pre-column derivatization of their amino and hydroxyl groups using 4-aminopyridine as a model compound

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s00216-007-1303-2openalex-snapshot
Hyphenation of reverse-phase HPLC and ICP-MS for metabolite profiling—application to a novel antituberculosis compound as a case study
inferredcites →https://doi.org/10.1007/s00216-007-1761-6openalex-snapshot
Use of the bromine isotope ratio in HPLC-ICP-MS and HPLC-ESI-MS analysis of a new drug in development
inferredcites →https://doi.org/10.1007/s00216-010-3611-1openalex-snapshot
Organometallic derivatizing agents in bioanalysis
inferredcites →https://doi.org/10.1007/s00216-011-5339-yopenalex-snapshot
Speciation analysis of bromine-containing drug metabolites in feces samples from a human in vivo study by means of HPLC/ICP-MS combined with on-line isotope dilution
inferredcites →https://doi.org/10.1007/s00216-012-6145-xopenalex-snapshot
Determination of S-containing drug metabolites from in vitro and in vivo metabolism studies by using LC-ICP/MS
inferredcites →https://doi.org/10.1016/j.aca.2012.06.040openalex-snapshot
Elemental labelling combined with liquid chromatography inductively coupled plasma mass spectrometry for quantification of biomolecules: A review
inferredcites →https://doi.org/10.1016/j.chroma.2016.04.006openalex-snapshot
Benzoyl chloride derivatization with liquid chromatography–mass spectrometry for targeted metabolomics of neurochemicals in biological samples
inferredcites →https://doi.org/10.1016/j.chroma.2016.08.067openalex-snapshot
High-sensitivity detection of biogenic amines with multiple reaction monitoring in fish based on benzoyl chloride derivatization
inferredcites →https://doi.org/10.1016/j.jchromb.2015.12.008openalex-snapshot
Determination of multiple human arsenic metabolites employing high performance liquid chromatography inductively coupled plasma mass spectrometry
inferredcites →https://doi.org/10.1016/j.jpba.2016.02.019openalex-snapshot
Determination of the total drug-related chlorine and bromine contents in human blood plasma using high performance liquid chromatography–tandem ICP-mass spectrometry (HPLC–ICP-MS/MS)
inferredcites →https://doi.org/10.1016/j.jpba.2018.02.031openalex-snapshot
Comparative evaluation of ICP sample introduction systems to be used in the metabolite profiling of chlorine-containing pharmaceuticals via HPLC-ICP-MS
inferredcites →https://doi.org/10.1016/j.talanta.2010.10.039openalex-snapshot
Determination of polyamines in human urine by precolumn derivatization with benzoyl chloride and high-performance liquid chromatography coupled with Q-time-of-flight mass spectrometry
inferredcites →https://doi.org/10.1016/j.trac.2017.09.020openalex-snapshot
High-performance liquid chromatography coupled to inductively coupled plasma – Mass spectrometry (HPLC-ICP-MS) for quantitative metabolite profiling of non-metal drugs
inferredcites →https://doi.org/10.1021/ac00292a003openalex-snapshot
Mass spectrometry of inductively coupled plasmas
inferredcites →https://doi.org/10.1021/ac202794qopenalex-snapshot
In Vivo Neurochemical Monitoring Using Benzoyl Chloride Derivatization and Liquid Chromatography–Mass Spectrometry
inferredcites →https://doi.org/10.1021/ac203165popenalex-snapshot
HPLC/ICP-MS in Combination with “Reverse” Online Isotope Dilution in Drug Metabolism Studies
inferredcites →https://doi.org/10.1021/ac9005606openalex-snapshot
Capillary HPLC−ICPMS and Tyrosine Iodination for the Absolute Quantification of Peptides Using Generic Standards
inferredcites →https://doi.org/10.1021/acs.analchem.6b04388openalex-snapshot
Quantitative Metabolite Profiling of an Amino Group Containing Pharmaceutical in Human Plasma via Precolumn Derivatization and High-Performance Liquid Chromatography-Inductively Coupled Plasma Mass Spectrometry
inferredcites →https://doi.org/10.1039/b307970hopenalex-snapshot
Determination of levothyroxine and its degradation products in pharmaceutical tablets by HPLC-UV-ICP-MS
inferredcites →https://doi.org/10.1039/b309028kopenalex-snapshot
Application of HPLC-ICP-MS to speciation of cisplatin and its degradation products in water containing different chloride concentrations and in human urine
inferredcites →https://doi.org/10.1039/b310530jopenalex-snapshot
Sensitive, simultaneous determination of P, S, Cl, Br and I containing pesticides in environmental samples by GC hyphenated with collision-cell ICP-MS
inferredcites →https://doi.org/10.1039/b415003aopenalex-snapshot
HPLC-ICP-MS compared with radiochemical detection for metabolite profiling of 3 H-bromohexine in rat urine and faeces
inferredcites →https://doi.org/10.1039/b718074hopenalex-snapshot
Labelling of proteins by use of iodination and detection by ICP-MS
inferredcites →https://doi.org/10.1039/c1ja10090dopenalex-snapshot
Iodination of proteins, proteomes and antibodies with potassium triodide for LA-ICP-MS based proteomic analyses
inferredcites →https://doi.org/10.1039/c7ja00385dopenalex-snapshot
A pre-column derivatization method allowing quantitative metabolite profiling of carboxyl and phenolic hydroxyl group containing pharmaceuticals in human plasma via liquid chromatography-inductively coupled plasma-tandem mass spectrometry (LC-ICP-MS/MS)
inferredcites →https://doi.org/10.1111/j.1751-908x.2007.00132.xopenalex-snapshot
Speciation Analysis for Iodine in Groundwater Using High Performance Liquid Chromatography‐Inductively Coupled Plasma‐Mass Spectrometry (HPLC‐ICP‐MS)
inferredcites →https://doi.org/10.1185/03007995.2011.583229openalex-snapshot
Dalfampridine: a brief review of its mechanism of action and efficacy as a treatment to improve walking in patients with multiple sclerosis
inferredcites →https://doi.org/10.2116/analsci.30.377openalex-snapshot
Novel Sensitive Determination Method for a Genotoxic Alkylating Agent, 4-Chloro-1-butanol, in Active Pharmaceutical Ingredients by LC-ICP-MS Employing Iodo Derivatization
inferredcites →https://doi.org/10.2116/analsci.30.845openalex-snapshot
Sensitive Quantitation of Residual Phenylhydrazine in Antipyrine by LC-ICP-MS with Iodo Derivatization
inferredcites →https://doi.org/10.3390/molecules21010075openalex-snapshot
Chemical Structure-Related Drug-Like Criteria of Global Approved Drugs

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4672186openalex-extracted
inferred← citeshttps://doi.org/10.1007/s44211-025-00739-3openalex-snapshot
Quantitative analysis of related substances in acetaminophen tablets using pre-column derivatization coupled with HPLC–ICP-MS
inferred← citeshttps://doi.org/10.1016/j.jpba.2024.116026openalex-snapshot
Quantification of oxaliplatin- and ioversol-related compounds in pharmaceutical formulations using novel HPLC-ICP-MS methods
inferred← citeshttps://doi.org/10.1016/j.sab.2024.106858openalex-snapshot
Solution cathode glow discharge coupled to atmospheric pressure chemical ionization for elemental detection of S and P in organic compounds
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