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Modified diterpenoids from the tuber of Icacina oliviformis as protein tyrosine phosphatase 1B inhibitors
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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LINCS: A linear constraint solver for molecular simulations
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Cytotoxic (9βH)‐Pimarane and (9βH)‐17‐Norpimarane Diterpenes from the Tuber of Icacina trichantha
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Bioactive Pimarane‐Type Diterpenes from Marine Organisms
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Pimarane diterpenes: Natural source, stereochemical configuration, and biological activity
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AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
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CHARMM : A program for macromolecular energy, minimization, and dynamics calculations
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Icacina oliviformis (Icacinaceae): A close look at an underexploited crop. I. Overview and ethnobotany
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Kinetics and molecular docking studies of pimarane-type diterpenes as protein tyrosine phosphatase (PTP1B) inhibitors from Aralia continentalis roots
inferredcites →https://doi.org/10.1016/j.bmc.2010.01.055openalex-snapshot
Novel thiophene derivatives as PTP1B inhibitors with selectivity and cellular activity
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The design strategy of selective PTP1B inhibitors over TCPTP
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Competitive protein tyrosine phosphatase 1B (PTP1B) inhibitors, prenylated caged xanthones from Garcinia hanburyi and their inhibitory mechanism
inferredcites →https://doi.org/10.1016/j.bmcl.2006.02.053openalex-snapshot
Inhibition of protein tyrosine phosphatase 1B by diterpenoids isolated from Acanthopanax koreanum
inferredcites →https://doi.org/10.1016/j.ejmech.2009.03.009openalex-snapshot
Synthesis and evaluation of some novel isochroman carboxylic acid derivatives as potential anti-diabetic agents
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Synthesis and evaluation of some novel dibenzo[b,d]furan carboxylic acids as potential anti-diabetic agents
inferredcites →https://doi.org/10.1016/j.ejmech.2014.09.036openalex-snapshot
Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition
inferredcites →https://doi.org/10.1016/j.ejmech.2016.04.014openalex-snapshot
Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity
inferredcites →https://doi.org/10.1016/j.lfs.2016.11.012openalex-snapshot
Trivaric acid, a new inhibitor of PTP1b with potent beneficial effect on diabetes
inferredcites →https://doi.org/10.1016/s0014-5793(03)00603-3openalex-snapshot
PTP1B: From the sidelines to the front lines!
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Diterpenoids from Humirianthera ampla
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Medicinal natural products: A biosynthetic approach
inferredcites →https://doi.org/10.1016/s1381-1177(97)00027-1openalex-snapshot
Enzyme-catalysed Baeyer–Villiger oxidations
inferredcites →https://doi.org/10.1021/acs.biochem.6b01025openalex-snapshot
Characterization of Protein Tyrosine Phosphatase 1B Inhibition by Chlorogenic Acid and Cichoric Acid
inferredcites →https://doi.org/10.1021/acs.jafc.8b02602openalex-snapshot
Momilactone and Related Diterpenoids as Potential Agricultural Chemicals
inferredcites →https://doi.org/10.1021/acs.jnatprod.5b00688openalex-snapshot
(9βH)-Pimaranes and Derivatives from the Tuber of Icacina trichantha
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Natural Products as Sources of New Drugs from 1981 to 2014
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Di-nor- and 17-nor-pimaranes from Icacina trichantha
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Evaluation of Diarylheptanoid–Terpene Adduct Enantiomers from Alpinia officinarum for Neuroprotective Activities
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Icacinlactone H and Icacintrichantholide from the Tuber of Icacina trichantha
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Pierisketolide A and Pierisketones B and C, Three Diterpenes with an Unusual Carbon Skeleton from the Roots of Pieris formosa
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Rhodomollacetals A–C, PTP1B Inhibitory Diterpenoids with a 2,3:5,6-Di-seco-grayanane Skeleton from the Leaves of Rhododendron molle
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Mollebenzylanols A and B, Highly Modified and Functionalized Diterpenoids with a 9-Benzyl-8,10-dioxatricyclo[5.2.1.01,5]decane Core from Rhododendron molle
inferredcites →https://doi.org/10.1021/bi035238popenalex-snapshot
Cellular Effects of Small Molecule PTP1B Inhibitors on Insulin Signaling
inferredcites →https://doi.org/10.1021/cm0342952openalex-snapshot
Molecular Dynamics Simulation of Organic−Inorganic Nanocomposites: Layering Behavior and Interlayer Structure of Organoclays
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Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked-Fragment Strategy
inferredcites →https://doi.org/10.1021/ja105035ropenalex-snapshot
Assigning Stereochemistry to Single Diastereoisomers by GIAO NMR Calculation: The DP4 Probability
inferredcites →https://doi.org/10.1021/jm100528popenalex-snapshot
A Focused Library of Protein Tyrosine Phosphatase Inhibitors
inferredcites →https://doi.org/10.1021/np50050a048openalex-snapshot
Terpenic Constituents from Icacina senegalensis
inferredcites →https://doi.org/10.1021/np5010328openalex-snapshot
17-Norpimaranes and (9βH)-17-Norpimaranes from the Tuber of Icacina trichantha
inferredcites →https://doi.org/10.1038/aps.2012.90openalex-snapshot
Natural products possessing protein tyrosine phosphatase 1B (PTP1B) inhibitory activity found in the last decades
inferredcites →https://doi.org/10.1038/s41598-016-0028-xopenalex-snapshot
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
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In-Silico Drug discovery approach targeting receptor tyrosine kinase-like orphan receptor 1 for cancer treatment
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Correction: Corrigendum: A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma
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Application of electronic circular dichroism in the study of supramolecular systems
inferredcites →https://doi.org/10.1039/c5ra01754hopenalex-snapshot
Natural and semisynthetic protein tyrosine phosphatase 1B (PTP1B) inhibitors as anti-diabetic agents
inferredcites →https://doi.org/10.1055/s-2006-960030openalex-snapshot
Terpenic Constituents fromIcacina senegalensis
inferredcites →https://doi.org/10.1063/1.470043openalex-snapshot
Accuracy and efficiency of the particle mesh Ewald method
inferredcites →https://doi.org/10.1063/1.4811291openalex-snapshot
Water polarization induced by thermal gradients: The extended simple point charge model (SPC/E)
inferredcites →https://doi.org/10.1074/jbc.273.41.26368openalex-snapshot
Molecular Basis for Substrate Specificity of Protein-tyrosine Phosphatase 1B
inferredcites →https://doi.org/10.1074/jbc.275.9.6308openalex-snapshot
Dynamics of Protein-tyrosine Phosphatases in Rat Adipocytes
inferredcites →https://doi.org/10.1096/fasebj.10.4.8647346openalex-snapshot
S‐Adenosylmetliionine and methylation
inferredcites →https://doi.org/10.1126/science.1187409openalex-snapshot
Atomic-Level Characterization of the Structural Dynamics of Proteins
inferredcites →https://doi.org/10.1126/science.282.5389.740openalex-snapshot
Pathways to a Protein Folding Intermediate Observed in a 1-Microsecond Simulation in Aqueous Solution
inferredcites →https://doi.org/10.1172/jci119552openalex-snapshot
Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes.
inferredcites →https://doi.org/10.1210/rp.59.1.287openalex-snapshot
Leptin Receptor Signaling and the Regulation of Mammalian Physiology
inferredcites →https://doi.org/10.3109/10409238.2013.819830openalex-snapshot
PTP1B: A simple enzyme for a complex world
inferredcites →https://doi.org/10.3109/14756366.2011.645240openalex-snapshot
Classification of difference between inhibition constants of an inhibitor to facilitate identifying the inhibition type
inferredcites →https://doi.org/10.3109/14756366.2015.1047358openalex-snapshot
Protein tyrosine phosphatase 1B inhibitors isolated from Artemisia roxburghiana
inferredcites →https://doi.org/10.3390/ani3010158openalex-snapshot
Ethnopharmacological Survey of Plants Used in the Traditional Treatment of Gastrointestinal Pain, Inflammation and Diarrhea in Africa: Future Perspectives for Integration into Modern Medicine
inferredcites →https://doi.org/10.4014/jmb.1303.03078openalex-snapshot
PTP1B Inhibitory Secondary Metabolites from Marine-Derived Fungal Strains Penicillium spp. and Eurotium sp.
inferredcites →https://doi.org/10.4172/2161-0398.1000206openalex-snapshot
MD Simulation Studies of Fumarase Reveal Thermo Dynamical Stability
inferredcites →https://doi.org/10.9790/2402-08734953openalex-snapshot
Nutritional and Phytochemical Composition of Utu (Icacina Senegalensis) and Sycamore (Ficus Sycomorus). Seeds
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Callnudoids A–H: Highly modified labdane diterpenoids with anti-inflammation from the leaves of Callicarpa nudiflora
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Naturally Occurring Cleistanthane Diterpenoids and Their Biological Activities
inferred← citeshttps://doi.org/10.1002/cjoc.202100764openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/978-981-99-7329-3_3openalex-snapshot
Classification of Diverse Novel Diterpenoids
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Secondary metabolites with fungicide potentials from the deep-sea seamount-derived fungus Talaromyces scorteus AS-242
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inferred← citeshttps://doi.org/10.1016/j.biopha.2022.113990openalex-snapshot
Status of research on natural protein tyrosine phosphatase 1B inhibitors as potential antidiabetic agents: Update
inferred← citeshttps://doi.org/10.1016/j.bse.2025.105093openalex-snapshot
Lignans from the leaves of Pieris formosa and their chemotaxonomic significance
inferred← citeshttps://doi.org/10.1016/j.cclet.2025.112289openalex-snapshot
Unprecedented ent-kaurane heterodimers from Icacina oliviformis: Potent anti-Helicobacter pylori leads targeting enoyl-ACP reductase FabI
inferred← citeshttps://doi.org/10.1016/j.molstruc.2023.136258openalex-snapshot
Structural and molecular insights of protein tyrosine phosphatase 1B (PTP1B) and its inhibitors as anti-diabetic agents
inferred← citeshttps://doi.org/10.1016/j.phrs.2022.106158openalex-snapshot
Potential of diterpenes as antidiabetic agents: Evidence from clinical and pre-clinical studies
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Isolation, absolute configurations and bioactivities of pestaphilones A–I: Undescribed methylated side chain containing-azaphilones from Pestalotiopsis oxyanthi
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Structurally diverse (9β-H)-pimarane derivatives with six frameworks from the leaves of Icacina oliviformis and their cytotoxic activities
inferred← citeshttps://doi.org/10.1021/acs.jafc.0c02720openalex-snapshot
Novel Protein Tyrosine Phosphatase 1B Inhibitor-Geranylated Flavonoid from Mulberry Leaves Ameliorates Insulin Resistance
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.0c01180openalex-snapshot
Structurally Diverse Diterpenoids from the Roots of Salvia deserta Based on Nine Different Skeletal Types
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Gelstriamine A, a Triamino Monoterpene Indole Alkaloid with a Caged 6/5/7/6/6/5 Scaffold and Analgesic Alkaloids from Gelsemium elegans Stems
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.6c00224openalex-snapshot
Modified Cytotoxic Terpenoids from the Tuber of Icacina trichantha
inferred← citeshttps://doi.org/10.1021/acs.orglett.6c00495openalex-snapshot
Discovery of seco -(9β-H)-Pimarane Diterpenoids from Icacina oliviformis with Synergistic Anti-Colorectal Cancer Activity
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Spirodesertols A and B, two highly modified spirocyclic diterpenoids with an unprecedented 6-isopropyl-3 H -spiro[benzofuran-2,1′-cyclohexane] motif from Salvia deserta
inferred← citeshttps://doi.org/10.1039/d1qo00374gopenalex-snapshot
Pimarane-derived diterpenoids with anti- Helicobacter pylori activity from the tuber of Icacina trichantha
inferred← citeshttps://doi.org/10.1093/bioadv/vbae205openalex-snapshot
Identification of promising dipeptidyl peptidase-4 and protein tyrosine phosphatase 1B inhibitors from selected terpenoids through molecular modeling
inferred← citeshttps://doi.org/10.3389/fchem.2022.882404openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/diabetology5050035openalex-snapshot
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