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An ESIPT-based AIE fluorescent probe to visualize mitochondrial hydrogen peroxide and its application in living cells and rheumatoid arthritis

https://doi.org/10.1039/d3ob00546a
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/adom.202100832openalex-snapshot
Insights into Optical Probes Based on Aggregation‐Induced Emission: from Restriction of Intramolecular Motions to Dark State
inferredcites →https://doi.org/10.1002/anie.201813935openalex-snapshot
Simultaneous Visualization of Endogenous Homocysteine, Cysteine, Glutathione, and their Transformation through Different Fluorescence Channels
inferredcites →https://doi.org/10.1002/art.41752openalex-snapshot
2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis
inferredcites →https://doi.org/10.1002/eji.202048952openalex-snapshot
Towards prevention of autoimmune diseases: The example of rheumatoid arthritis
inferredcites →https://doi.org/10.1007/s00296-001-0163-xopenalex-snapshot
Lipid peroxidation, some extracellular antioxidants, and antioxidant enzymes in serum of patients with rheumatoid arthritis
inferredcites →https://doi.org/10.1007/s00296-011-2135-0openalex-snapshot
Serum level of oxidative stress marker is dramatically low in patients with rheumatoid arthritis treated with tocilizumab
inferredcites →https://doi.org/10.1007/s10067-020-05001-xopenalex-snapshot
Treatment strategies are more important than drugs in the management of rheumatoid arthritis
inferredcites →https://doi.org/10.1007/s10753-021-01589-7openalex-snapshot
AGE/Non-AGE Glycation: An Important Event in Rheumatoid Arthritis Pathophysiology
inferredcites →https://doi.org/10.1016/j.bioorg.2022.106026openalex-snapshot
A combined “AIE + ESIPT” fluorescent probe for detection of lipase activity
inferredcites →https://doi.org/10.1016/j.cclet.2020.11.048openalex-snapshot
Nanotechnology for diagnosis and therapy of rheumatoid arthritis: Evolution towards theranostic approaches
inferredcites →https://doi.org/10.1016/j.cclet.2021.03.074openalex-snapshot
Monitoring intracellular pH fluctuation with an excited-state intramolecular proton transfer-based ratiometric fluorescent sensor
inferredcites →https://doi.org/10.1016/j.cclet.2021.09.036openalex-snapshot
A multisite-binding fluorescent probe for simultaneous monitoring of mitochondrial homocysteine, cysteine and glutathione in live cells and zebrafish
inferredcites →https://doi.org/10.1016/j.dyepig.2023.111137openalex-snapshot
Rational design AIE fluorescent probes for wash-free and lipid droplet specific imaging of fatty liver based on coumarin
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2019.12.007openalex-snapshot
Relevance of Nrf2 and heme oxygenase-1 in articular diseases
inferredcites →https://doi.org/10.1016/j.snb.2017.02.080openalex-snapshot
A fluorescent probe with “AIE + ESIPT” characteristics for Cu2+ and F− ions estimation
inferredcites →https://doi.org/10.1016/j.snb.2021.130038openalex-snapshot
Elegant cooperation of AIE, ESIPT and ICT effects into tetraarylimidazole-based fluorophore and its tuning for ratiometric detection of carbon monoxide
inferredcites →https://doi.org/10.1016/j.snb.2023.133320openalex-snapshot
AIE-based fluorescence probes with different torsional configurations for monitoring human serum albumin
inferredcites →https://doi.org/10.1016/j.tetlet.2017.08.016openalex-snapshot
A benzothizole-based fluorescent probe for Hg 2+ recognition utilizing ESIPT coupled AIE characteristics
inferredcites →https://doi.org/10.1016/s0891-5849(00)00261-6openalex-snapshot
Sensitive and nonenzymatic measurement of hydrogen peroxide in biological systems
inferredcites →https://doi.org/10.1016/s2215-0366(18)30255-4openalex-snapshot
Rheumatoid arthritis and depression: an inflammatory perspective
inferredcites →https://doi.org/10.1016/s2665-9913(20)30221-6openalex-snapshot
Cardiovascular risk in inflammatory arthritis: rheumatoid arthritis and gout
inferredcites →https://doi.org/10.1021/acs.analchem.0c05118openalex-snapshot
Highly Sensitive Near-Infrared Imaging of Peroxynitrite Fluxes in Inflammation Progress
inferredcites →https://doi.org/10.1021/acs.analchem.1c02831openalex-snapshot
A Fast-Responsive OFF–ON Near-Infrared-II Fluorescent Probe for In Vivo Detection of Hypochlorous Acid in Rheumatoid Arthritis
inferredcites →https://doi.org/10.1021/acs.jmedchem.7b01775openalex-snapshot
Synthesis and Evaluation of Hydrogen Peroxide Sensitive Prodrugs of Methotrexate and Aminopterin for the Treatment of Rheumatoid Arthritis
inferredcites →https://doi.org/10.1021/acssensors.2c01550openalex-snapshot
Schiff Base Aggregation-Induced Emission Luminogens for Sensing Applications: A Review
inferredcites →https://doi.org/10.1021/ja411547jopenalex-snapshot
In Vivo Targeting of Hydrogen Peroxide by Activatable Cell-Penetrating Peptides
inferredcites →https://doi.org/10.1021/ja510421qopenalex-snapshot
Mitochondrial Induced and Self-Monitored Intrinsic Apoptosis by Antitumor Theranostic Prodrug: In Vivo Imaging and Precise Cancer Treatment
inferredcites →https://doi.org/10.1038/nature01661openalex-snapshot
Evolving concepts of rheumatoid arthritis
inferredcites →https://doi.org/10.1038/ncprheum0047openalex-snapshot
Mechanisms of Disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis
inferredcites →https://doi.org/10.1038/s41590-020-00816-xopenalex-snapshot
The immunology of rheumatoid arthritis
inferredcites →https://doi.org/10.1039/c7cc07845eopenalex-snapshot
Long-wavelength fluorescent boronate probes for the detection and intracellular imaging of peroxynitrite
inferredcites →https://doi.org/10.1039/c9ob02561hopenalex-snapshot
Recent progress on the organic and metal complex-based fluorescent probes for monitoring nitric oxide in living biological systems
inferredcites →https://doi.org/10.1039/d1ce00317hopenalex-snapshot
Recent advances in excited state intramolecular proton transfer mechanism-based solid state fluorescent materials and stimuli-responsive fluorescence switching
inferredcites →https://doi.org/10.1039/d1cs00239bopenalex-snapshot
Twisted intramolecular charge transfer (TICT) and twists beyond TICT: from mechanisms to rational designs of bright and sensitive fluorophores
inferredcites →https://doi.org/10.1039/d1sc02165fopenalex-snapshot
Fluorescent probes for visualizing ROS-associated proteins in disease
inferredcites →https://doi.org/10.1039/d2an00543copenalex-snapshot
A novel AIE fluorescent probe for the monitoring of aluminum ions in living cells and zebrafish
inferredcites →https://doi.org/10.1039/d2cc06556hopenalex-snapshot
Excited-state intramolecular proton transfer (ESIPT)-based fluorescent probes for biomarker detection: design, mechanism, and application
inferredcites →https://doi.org/10.1039/d3ob00006kopenalex-snapshot
Effect of different substituents on the fluorescence properties of precursors of synthetic GFP analogues and a polarity-sensitive lipid droplet probe with AIE properties for imaging cells and zebrafish
inferredcites →https://doi.org/10.1042/cs20190728openalex-snapshot
Skeletal muscle redox signaling in rheumatoid arthritis
inferredcites →https://doi.org/10.1080/10715762.2019.1629586openalex-snapshot
Role of redox imbalance and cytokines in mediating oxidative damage and disease progression of patients with rheumatoid arthritis
inferredcites →https://doi.org/10.1089/ars.2010.3835openalex-snapshot
Deficiency of Nrf2 Accelerates the Effector Phase of Arthritis and Aggravates Joint Disease
inferredcites →https://doi.org/10.1136/ard.2009.111211openalex-snapshot
Oxidative damage in synovial tissue is associated with in vivo hypoxic status in the arthritic joint
inferredcites →https://doi.org/10.1186/ar3424openalex-snapshot
Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis
inferredcites →https://doi.org/10.1517/14712598.1.6.971openalex-snapshot
Gene therapy for rheumatoid arthritis
inferredcites →https://doi.org/10.3390/cells10113017openalex-snapshot
Recent Advances in Understanding the Pathogenesis of Rheumatoid Arthritis: New Treatment Strategies
inferredcites →https://doi.org/10.7326/0003-4819-153-1-201007060-00003openalex-snapshot
Sexually Transmitted Diseases Among Users of Erectile Dysfunction Drugs: Analysis of Claims Data

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4809863openalex-extracted
Mechanistic Insights into Excited-State Proton Transfer in 2-(2'-Hydroxy-5'-Bromo)Phenylbenzimidazole: A Spectroscopic and Tddft Study
inferred← citeshttps://doi.org/10.1002/idm2.12130openalex-snapshot
Emerging advances in fluorescence imaging and phototherapy of arthritis
inferred← citeshttps://doi.org/10.1002/tcr.202500109openalex-snapshot
Advancements in the Design and Development of Organic Fluorophores for the Excited State Intramolecular Proton Transfer Phenomenon
inferred← citeshttps://doi.org/10.1016/j.aca.2024.343442openalex-snapshot
An activatable “AIE + ESIPT” fluorescent probe for dual-imaging of lipid droplets and hydrogen peroxide in drug-induced liver injury model
inferred← citeshttps://doi.org/10.1016/j.bios.2024.117069openalex-snapshot
Innovations in aggregation-induced emission materials for theranostics in the musculoskeletal system
inferred← citeshttps://doi.org/10.1016/j.bios.2025.117862openalex-snapshot
Molecular crossbreeding-engineered self-calibrating probe with large emission shift for dual near-infrared imaging of therapy-induced senescence
inferred← citeshttps://doi.org/10.1016/j.ccr.2025.217441openalex-snapshot
Fluorescence visualization of small molecular biomarkers and microenvironmental factors in chronic diseases
inferred← citeshttps://doi.org/10.1016/j.ccr.2025.217462openalex-snapshot
Recent advances in fluorescent probes for the detection of biomarkers in arthritis
inferred← citeshttps://doi.org/10.1016/j.ccr.2026.217628openalex-snapshot
Optical probes for redox imaging: A comparative review of fluorescent, bioluminescent, and chemiluminescent strategies for in vivo sensing of ROS, RNS, and RSS
inferred← citeshttps://doi.org/10.1016/j.dyepig.2025.113125openalex-snapshot
Research progress in the design and synthesis of hydrogen peroxide fluorescent probe
inferred← citeshttps://doi.org/10.1016/j.jpha.2025.101509openalex-snapshot
Synovial microenvironment and fluorescence imaging for early rheumatoid arthritis diagnosis
inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.139262openalex-snapshot
Novel triphenylamine-pyrene-based AIEgens: Specific detection and imaging of H2O2 in aqueous solution and cells
inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.140429openalex-snapshot
Novel spiropyran fluorescent probes based on ESIPT and ICT: pH Response & Cyanide Detection
inferred← citeshttps://doi.org/10.1016/j.molstruc.2025.142876openalex-snapshot
A Schiff base dual mode“Turn-On” fluorescent probe for selective detection of HClO/ClO− in buffer
inferred← citeshttps://doi.org/10.1016/j.saa.2026.127580openalex-snapshot
Monitoring the upregulated hydrogen peroxide levels in cells and living organisms under the microcystin-LR exposure
inferred← citeshttps://doi.org/10.1016/j.snb.2024.135287openalex-snapshot
AIEgen-caged ultrafast photochemical delivery and visualization of nitric oxide
inferred← citeshttps://doi.org/10.1016/j.tet.2024.134134openalex-snapshot
Synthesis and application of the AIE-ESIPT fluorescent probe for Cystiene detection: Crystal structure analysis and DFT calculation
inferred← citeshttps://doi.org/10.1021/acs.analchem.4c02152openalex-snapshot
Coordination Synergistic-Induced J-Aggregation Enhanced Fluorescent Performance of HBT-Excimers and Imaging Applications
inferred← citeshttps://doi.org/10.1021/acs.chemrev.3c00892openalex-snapshot
Ex Tenebris Lux: Illuminating Reactive Oxygen and Nitrogen Species with Small Molecule Probes
inferred← citeshttps://doi.org/10.1039/9781837676453-00117openalex-snapshot
Aggregation-induced Emission for Bioimaging and Diagnostic Applications
inferred← citeshttps://doi.org/10.1039/d3cs01118fopenalex-snapshot
Twisted intramolecular charge transfer (TICT) based fluorescent probes and imaging agents
inferred← citeshttps://doi.org/10.1039/d4ra06147kopenalex-snapshot
Insights into ESIPT-induced multicolor fluorescence emission in 2-(2′-hydroxy-5′-bromo)phenylbenzimidazole: a spectroscopic and TDDFT study
inferred← citeshttps://doi.org/10.1039/d5cp03573bopenalex-snapshot
Computational unveiling of solvent-polarity-dependent ESDPT behavior in typical asymmetric PIQ fluorophores
inferred← citeshttps://doi.org/10.3390/molecules29215181openalex-snapshot
A Novel Benzothiazole-Based Fluorescent AIE Probe for the Detection of Hydrogen Peroxide in Living Cells
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