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Biosynthesis of polyamines and polyamine-containing molecules
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/bf00232509openalex-snapshotEvidence for the occurrence of polyamine oxidase in the dicotyledonous plant Medicago sativa L. (alfalfa)
inferredcites →https://doi.org/10.1007/s00425-009-0960-0openalex-snapshotAccumulation of hydroxycinnamic acid amides induced by pathogen infection and identification of agmatine coumaroyltransferase in Arabidopsis thaliana
inferredcites →https://doi.org/10.1016/0006-291x(78)91630-3openalex-snapshotAnti-proliferative properties of DL-α-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase
inferredcites →https://doi.org/10.1016/0378-1097(88)90214-5openalex-snapshotOccurrence of aminopropylcadaverine and its aminopropyl derivatives aminopentylnorspermidine and N, N′ -bis(3-aminopropyl)cadaverine in Halococcus acetoinfaciens
inferredcites →https://doi.org/10.1016/0378-1119(84)90113-6openalex-snapshotExpression of the cloned genes encoding the putrescine biosynthetic enzymes and methionine adenosyltransferase of Escherichia coli (speA, speB, speC and metK)
inferredcites →https://doi.org/10.1016/j.febslet.2011.07.038openalex-snapshotMolecular machines encoded by bacterially-derived multi-domain gene fusions that potentially synthesize,N-methylate and transfer long chain polyamines in diatoms
inferredcites →https://doi.org/10.1016/j.ijfoodmicro.2014.01.009openalex-snapshotPutrescine production via the ornithine decarboxylation pathway improves the acid stress survival of Lactobacillus brevis and is part of a horizontally transferred acid resistance locus
inferredcites →https://doi.org/10.1016/s0378-1119(98)00027-4openalex-snapshotSpermine is not essential for growth of Saccharomyces cerevisiae: identification of the SPE4 gene (spermine synthase) and characterization of a spe4 deletion mutant
inferredcites →https://doi.org/10.1021/bi001651aopenalex-snapshotVibriobactin Biosynthesis in Vibrio cholerae: VibH Is an Amide Synthase Homologous to Nonribosomal Peptide Synthetase Condensation Domains
inferredcites →https://doi.org/10.1021/bi0016523openalex-snapshotReconstitution and Characterization of the Vibrio cholerae Vibriobactin Synthetase from VibB, VibE, VibF, and VibH
inferredcites →https://doi.org/10.1021/bi6023447openalex-snapshotX-ray Structure of Paramecium bursaria Chlorella Virus Arginine Decarboxylase: Insight into the Structural Basis for Substrate Specificity
inferredcites →https://doi.org/10.1021/bi802277hopenalex-snapshotEvolution of Enzymatic Activities in the Enolase Superfamily: Stereochemically Distinct Mechanisms in Two Families of cis,cis-Muconate Lactonizing Enzymes
inferredcites →https://doi.org/10.1021/bi900075dopenalex-snapshotCrystal Structure of the Acid-Induced Arginine Decarboxylase from Escherichia coli : Reversible Decamer Assembly Controls Enzyme Activity
inferredcites →https://doi.org/10.1021/bi9915115openalex-snapshotX-ray Structure of Ornithine Decarboxylase from Trypanosoma brucei: The Native Structure and the Structure in Complex with α-Difluoromethylornithine,
inferredcites →https://doi.org/10.1021/ja00476a050openalex-snapshotCatalytic irreversible inhibition of mammalian ornithine decarboxylase (E.C.4.1.1.17) by substrate and product analogs
inferredcites →https://doi.org/10.1021/ja0119088openalex-snapshotPetrobactin, a Photoreactive Siderophore Produced by the Oil-Degrading Marine Bacterium Marinobacter hydrocarbonoclasticus
inferredcites →https://doi.org/10.1021/np0499766openalex-snapshotPalmitoylputrescine, an Antibiotic Isolated from the Heterologous Expression of DNA Extracted from Bromeliad Tank Water
inferredcites →https://doi.org/10.1038/emboj.2011.5openalex-snapshotLinkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase
inferredcites →https://doi.org/10.1038/nsmb.1889openalex-snapshotA paralog of lysyl-tRNA synthetase aminoacylates a conserved lysine residue in translation elongation factor P
inferredcites →https://doi.org/10.1038/srep19501openalex-snapshotComprehensive Structural Characterization of the Bacterial Homospermidine Synthase–an Essential Enzyme of the Polyamine Metabolism
inferredcites →https://doi.org/10.1039/b809353aopenalex-snapshotPetrobactin biosynthesis: AsbB catalyzes condensation of spermidine with N8-citryl-spermidine and its N1-(3,4-dihydroxybenzoyl) derivative
inferredcites →https://doi.org/10.1039/b823147hopenalex-snapshotEnantioselective desymmetrisation of citric acid catalysed by the substrate-tolerant petrobactin biosynthetic enzyme AsbA
inferredcites →https://doi.org/10.1042/0264-6021:3530403openalex-snapshotCharacterization of monocot and dicot plant S-adenosyl-l-methionine decarboxylase gene families including identification in the mRNA of a highly conserved pair of upstream overlapping open reading frames
inferredcites →https://doi.org/10.1042/0264-6021:3600657openalex-snapshotIdentification of essential active-site residues in ornithine decarboxylase of Nicotiana glutinosa decarboxylating both l-ornithine and l-lysine
inferredcites →https://doi.org/10.1042/bj1170017openalex-snapshotConcentrations of putrescine and polyamines and their enzymic synthesis during androgen-induced prostatic growth
inferredcites →https://doi.org/10.1042/bj3120083openalex-snapshotA new model for disruption of the ornithine decarboxylase gene, SPE1, in Saccharomyces cerevisiae exhibits growth arrest and genetic instability at the MAT locus
inferredcites →https://doi.org/10.1073/pnas.78.5.2869openalex-snapshotIdentification of hypusine, an unusual amino acid, in a protein from human lymphocytes and of spermidine as its biosynthetic precursor.
inferredcites →https://doi.org/10.1073/pnas.96.26.14777openalex-snapshotHomospermidine synthase, the first pathway-specific enzyme of pyrrolizidine alkaloid biosynthesis, evolved from deoxyhypusine synthase
inferredcites →https://doi.org/10.1074/jbc.271.47.29576openalex-snapshotThe Upstream Open Reading Frame of the mRNA Encoding S-Adenosylmethionine Decarboxylase Is a Polyamine-responsive Translational Control Element
inferredcites →https://doi.org/10.1074/jbc.273.49.32500openalex-snapshotThe Inhibitory Upstream Open Reading Frame from Mammalian S-Adenosylmethionine Decarboxylase mRNA Has a Strict Sequence Specificity in Critical Positions
inferredcites →https://doi.org/10.1074/jbc.275.11.8097openalex-snapshotIn the Human Malaria Parasite Plasmodium falciparum,Polyamines Are Synthesized by a Bifunctional Ornithine Decarboxylase,S-Adenosylmethionine Decarboxylase
inferredcites →https://doi.org/10.1074/jbc.m110.107219openalex-snapshotEvolution and Multifarious Horizontal Transfer of an Alternative Biosynthetic Pathway for the Alternative Polyamine sym-Homospermidine
inferredcites →https://doi.org/10.1074/jbc.m110.163154openalex-snapshotEvolution and Multiplicity of Arginine Decarboxylases in Polyamine Biosynthesis and Essential Role in Bacillus subtilis Biofilm Formation
inferredcites →https://doi.org/10.1074/jbc.m111.307835openalex-snapshotAlternative Spermidine Biosynthetic Route Is Critical for Growth of Campylobacter jejuni and Is the Dominant Polyamine Pathway in Human Gut Microbiota
inferredcites →https://doi.org/10.1074/jbc.m115.656785openalex-snapshotDeoxyhypusine Modification of Eukaryotic Translation Initiation Factor 5A (eIF5A) Is Essential for Trypanosoma brucei Growth and for Expression of Polyprolyl-containing Proteins
inferredcites →https://doi.org/10.1074/jbc.m205699200openalex-snapshotPlant C-N Hydrolases and the Identification of a Plant N-Carbamoylputrescine Amidohydrolase Involved in Polyamine Biosynthesis
inferredcites →https://doi.org/10.1074/jbc.m206161200openalex-snapshotAbrogation of Upstream Open Reading Frame-mediated Translational Control of a Plant S-Adenosylmethionine Decarboxylase Results in Polyamine Disruption and Growth Perturbations
inferredcites →https://doi.org/10.1074/jbc.m409246200openalex-snapshotCrystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily
inferredcites →https://doi.org/10.1074/jbc.m413332200openalex-snapshotN1-Aminopropylagmatine, a New Polyamine Produced as a Key Intermediate in Polyamine Biosynthesis of an Extreme Thermophile, Thermus thermophilus
inferredcites →https://doi.org/10.1074/jbc.m704066200openalex-snapshotPhylogenetic Diversity and the Structural Basis of Substrate Specificity in the β/α-Barrel Fold Basic Amino Acid Decarboxylases
inferredcites →https://doi.org/10.1074/jbc.m900110200openalex-snapshotAn Alternative Polyamine Biosynthetic Pathway Is Widespread in Bacteria and Essential for Biofilm Formation in Vibrio cholerae
inferredcites →https://doi.org/10.1093/jb/mvj034openalex-snapshotThe Post-Translational Synthesis of a Polyamine-Derived Amino Acid, Hypusine, in the Eukaryotic Translation Initiation Factor 5A (eIF5A)
inferredcites →https://doi.org/10.1093/pcp/pcu047openalex-snapshotPolyamine Oxidase 7 is a Terminal Catabolism-Type Enzyme in Oryza sativa and is Specifically Expressed in Anthers
inferredcites →https://doi.org/10.1099/00221287-137-7-1737openalex-snapshotPurification and some properties of carboxynorspermidine synthase participating in a novel biosynthetic pathway for norspermidine in Vibrio alginolyticus
inferredcites →https://doi.org/10.1099/mic.0.26009-0openalex-snapshotIdentification of the putrescine biosynthetic genes in Pseudomonas aeruginosa and characterization of agmatine deiminase and N-carbamoylputrescine amidohydrolase of the arginine decarboxylase pathway
inferredcites →https://doi.org/10.1104/pp.114.2.445openalex-snapshotPutrescine Aminopropyltransferase Is Responsible for Biosynthesis of Spermidine, Spermine, and Multiple Uncommon Polyamines in Osmotic Stress-Tolerant Alfalfa
inferredcites →https://doi.org/10.1105/tpc.112.095885openalex-snapshotLysine Decarboxylase Catalyzes the First Step of Quinolizidine Alkaloid Biosynthesis and Coevolved with Alkaloid Production in Leguminosae
inferredcites →https://doi.org/10.1111/mmi.13066openalex-snapshotDifferent polyamine pathways from bacteria have replaced eukaryotic spermidine biosynthesis in ciliates T etrahymena thermophila and P aramecium tetaurelia
inferredcites →https://doi.org/10.1128/aem.02169-09openalex-snapshotExpanding Small-Molecule Functional Metagenomics through Parallel Screening of Broad-Host-Range Cosmid Environmental DNA Libraries in Diverse Proteobacteria
inferredcites →https://doi.org/10.1128/aem.03461-13openalex-snapshotDisruption of Putrescine Biosynthesis in Shewanella oneidensis Enhances Biofilm Cohesiveness and Performance in Cr(VI) Immobilization
inferredcites →https://doi.org/10.1128/ec.00047-09openalex-snapshotRNA Interference-Mediated Silencing of Ornithine Decarboxylase and Spermidine Synthase Genes in Trypanosoma brucei Provides Insight into Regulation of Polyamine Biosynthesis
inferredcites →https://doi.org/10.1128/jb.00279-10openalex-snapshotDual Biosynthesis Pathway for Longer-Chain Polyamines in the Hyperthermophilic Archaeon Thermococcus kodakarensis
inferredcites →https://doi.org/10.1128/jb.00381-09openalex-snapshotPolyamines Are Not Required for Aerobic Growth of Escherichia coli : Preparation of a Strain with Deletions in All of the Genes for Polyamine Biosynthesis
inferredcites →https://doi.org/10.1128/jb.01515-14openalex-snapshotIdentification of a Novel Aminopropyltransferase Involved in the Synthesis of Branched-Chain Polyamines in Hyperthermophiles
inferredcites →https://doi.org/10.1128/jb.178.1.54-60.1996openalex-snapshotThe ornithine decarboxylase gene odc is required for alcaligin siderophore biosynthesis in Bordetella spp.: putrescine is a precursor of alcaligin
inferredcites →https://doi.org/10.1128/jb.179.16.5118-5125.1997openalex-snapshotIdentification and analysis of a gene encoding L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase involved in the 1,3-diaminopropane production pathway in Acinetobacter baumannii
inferredcites →https://doi.org/10.1128/jb.182.23.6732-6741.2000openalex-snapshotGene Cloning and Molecular Characterization of Lysine Decarboxylase from Selenomonas ruminantium Delineate Its Evolutionary Relationship to Ornithine Decarboxylases from Eukaryotes
inferredcites →https://doi.org/10.1371/journal.pone.0077188openalex-snapshotA Comprehensive Analysis of the Importance of Translation Initiation Factors for Haloferax volcanii Applying Deletion and Conditional Depletion Mutants
inferredcites →https://doi.org/10.2323/jgam.50.289openalex-snapshotDistribution of norspermidine as a cellular polyamine within micro green algae including non-photosynthetic achlorophyllous Polytoma, Polytomella, Prototheca and Helicosporidium
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/app.71115openalex-snapshotHighly Thermally Stable Bio‐Based Polyimides Derived From 2,5‐Thiophenedicarboxylic Acid: Synthesis and Structure–Property Relationships
inferred← citeshttps://doi.org/10.1002/jms.4770openalex-snapshotFragmentation reactions of protonated α,ω‐diamino carboxylic acids: The importance of functional group interactions
inferred← citeshttps://doi.org/10.1007/s00253-022-12110-xopenalex-snapshotHighly efficient biosynthesis of spermidine from L-homoserine and putrescine using an engineered Escherichia coli with NADPH self-sufficient system
inferred← citeshttps://doi.org/10.1016/j.aca.2019.02.001openalex-snapshotAn extendable all-in-one injection twin derivatization LC-MS/MS strategy for the absolute quantification of multiple chemical-group-based submetabolomes
inferred← citeshttps://doi.org/10.1016/j.biocel.2017.10.015openalex-snapshotComprehensive analysis of polyamine transport and biosynthesis in the dominant human gut bacteria: Potential presence of novel polyamine metabolism and transport genes
inferred← citeshttps://doi.org/10.1016/j.cej.2025.167413openalex-snapshotMulti-strategy metabolic reprogramming of Serratia marcescens HBQA7 for high-efficiency spermidine biosynthesis via the carboxyaminopropylagmatine pathway
inferred← citeshttps://doi.org/10.1016/j.cmet.2018.04.009openalex-snapshotArginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity
inferred← citeshttps://doi.org/10.1016/j.fbio.2026.110083openalex-snapshotEfficient ergothioneine production in Saccharomyces cerevisiae through synergistic multilevel metabolic engineering and adaptive process development
inferred← citeshttps://doi.org/10.1016/j.fsi.2019.03.075openalex-snapshotRainbow trout (Oncorhynchus mykiss) urea cycle and polyamine synthesis gene families show dynamic expression responses to inflammation
inferred← citeshttps://doi.org/10.1016/j.fsi.2020.01.026openalex-snapshotArginine, ornithine and citrulline supplementation in rainbow trout: Free amino acid dynamics and gene expression responses to bacterial infection
inferred← citeshttps://doi.org/10.1016/j.jbc.2021.101219openalex-snapshotDiscovery of ancestral L-ornithine and L-lysine decarboxylases reveals parallel, pseudoconvergent evolution of polyamine biosynthesis
inferred← citeshttps://doi.org/10.1016/j.jbc.2023.105005openalex-snapshotNeofunctionalization of S-adenosylmethionine decarboxylase into pyruvoyl-dependent L-ornithine and L-arginine decarboxylases is widespread in bacteria and archaea
inferred← citeshttps://doi.org/10.1016/j.jece.2023.109926openalex-snapshotGreen polyampholytic ionic scavengers as an alternative to crude oil derived chelating resins for removal of toxic metals from aqueous solutions
inferred← citeshttps://doi.org/10.1038/s41598-020-71652-0openalex-snapshotPlant growth promoting rhizobacteria isolated from halophytes and drought-tolerant plants: genomic characterisation and exploration of phyto-beneficial traits
inferred← citeshttps://doi.org/10.1038/s42003-022-03276-1openalex-snapshotStructural and biochemical characterisation of the Providencia stuartii arginine decarboxylase shows distinct polymerisation and regulation
inferred← citeshttps://doi.org/10.1039/d0np00064gopenalex-snapshotIdentification and characterization of enzymes involved in the biosynthesis of pyrimidine nucleoside antibiotics
inferred← citeshttps://doi.org/10.1042/bcj20170900openalex-snapshotCrystal structure of thermospermine synthase from Medicago truncatula and substrate discriminatory features of plant aminopropyltransferases
inferred← citeshttps://doi.org/10.1080/15592324.2020.1761080openalex-snapshotThe unknown soldier in citrus plants: polyamines-based defensive mechanisms against biotic and abiotic stresses and their relationship with other stress-associated metabolites
inferred← citeshttps://doi.org/10.1093/gbe/evy228openalex-snapshotA novel subfamily of bacterial AAT-fold basic amino acid decarboxylases and functional characterization of its first representative: Pseudomonas aeruginosa LdcA
inferred← citeshttps://doi.org/10.1093/jas/skad196openalex-snapshotCompound organic acid could improve the growth performance, immunity and antioxidant properties, and intestinal health by altering the microbiota profile of weaned piglets
inferred← citeshttps://doi.org/10.1099/mic.0.001293openalex-snapshotThe Sinorhizobium meliloti NspS-MbaA system affects biofilm formation, exopolysaccharide production and motility in response to specific polyamines
inferred← citeshttps://doi.org/10.1111/1462-2920.14020openalex-snapshotMetabolomics of tomato xylem sap during bacterial wilt reveals Ralstonia solanacearum produces abundant putrescine, a metabolite that accelerates wilt disease
inferred← citeshttps://doi.org/10.1111/mmi.14006openalex-snapshotHomospermidine biosynthesis in the cyanobacterium Anabaena requires a deoxyhypusine synthase homologue and is essential for normal diazotrophic growth
inferred← citeshttps://doi.org/10.1111/pbi.14208openalex-snapshotAn ancient cis‐element targeted by Ralstonia solanacearum TALE‐like effectors facilitates the development of a promoter trap that could confer broad‐spectrum wilt resistance
inferred← citeshttps://doi.org/10.1111/pbi.14227openalex-snapshotOverexpression of OsACL5 triggers environmentally‐dependent leaf rolling and reduces grain size in rice
inferred← citeshttps://doi.org/10.1111/tpj.70455openalex-snapshotFunctional characterization of NLG14 provides novel insights into the synergistic improvement of grain length, grain quality and salt tolerance in rice
inferred← citeshttps://doi.org/10.1128/msystems.01003-20openalex-snapshotProduction and Excretion of Polyamines To Tolerate High Ammonia, a Case Study on Soil Ammonia-Oxidizing Archaeon “ Candidatus Nitrosocosmicus agrestis”
inferred← citeshttps://doi.org/10.1128/spectrum.01633-22openalex-snapshotTarget of Rapamycin Mediated Ornithine Decarboxylase Antizyme Modulate Intracellular Putrescine and Ganoderic Acid Content in Ganoderma lucidum
inferred← citeshttps://doi.org/10.1371/journal.ppat.1007404openalex-snapshotA dual regulatory circuit consisting of S-adenosylmethionine decarboxylase protein and its reaction product controls expression of the paralogous activator prozyme in Trypanosoma brucei
inferred← citeshttps://doi.org/10.1515/hsz-2025-0158openalex-snapshotNew polyamine oxidases from Ogataea parapolymorpha DL-1: expanding view on non-conventional yeast polyamine catabolism
inferred← citeshttps://doi.org/10.3389/fmicb.2023.1273211openalex-snapshotGenomic insight into strategy, interaction and evolution of nitrifiers in metabolizing key labile-dissolved organic nitrogen in different environmental niches
inferred← citeshttps://doi.org/10.3389/fpls.2019.00320openalex-snapshotStructural Study of Agmatine Iminohydrolase From Medicago truncatula, the Second Enzyme of the Agmatine Route of Putrescine Biosynthesis in Plants
inferred← citeshttps://doi.org/10.3389/fpls.2025.1483417openalex-snapshotOrnithine enhances common bean growth and defense against white mold disease via interfering with SsOAH and diminishing the biosynthesis of oxalic acid in Sclerotinia sclerotiorum
inferred← citeshttps://doi.org/10.3389/fpls.2025.1636076openalex-snapshotOptimized LC-MS method for simultaneous polyamine profiling and ADC/ODC activity quantification and evidence that ADCs are indispensable for flower development in tomato
inferred← citeshttps://doi.org/10.3390/agronomy11040735openalex-snapshotExogenously Applied Polyamines Reduce Reactive Oxygen Species, Enhancing Cell Division and the Shoot Regeneration from Brassica oleracea L. var. capitata Protoplasts
inferred← citeshttps://doi.org/10.3390/biom14040463openalex-snapshotCharacterization of an Arginine Decarboxylase from Streptococcus pneumoniae by Ultrahigh-Performance Liquid Chromatography–Tandem Mass Spectrometry
inferred← citeshttps://doi.org/10.3390/cancers14061375openalex-snapshotPotential Metabolite Markers for Pancreatic Cancer Identified by Metabolomic Analysis of Induced Cancer-Associated Fibroblasts
inferred← citeshttps://doi.org/10.3390/cells12141829openalex-snapshotStructural and Kinetic Characterization of the SpeG Spermidine/Spermine N-acetyltransferase from Methicillin-Resistant Staphylococcus aureus USA300
inferred← citeshttps://doi.org/10.3390/ijms242417503openalex-snapshotTranslation Fidelity and Respiration Deficits in CLPP-Deficient Tissues: Mechanistic Insights from Mitochondrial Complexome Profiling
inferred← citeshttps://doi.org/10.3390/ijms26020534openalex-snapshotNeohesperidin Mitigates High-Fat-Diet-Induced Colitis In Vivo by Modulating Gut Microbiota and Enhancing SCFAs Synthesis
inferred← citeshttps://doi.org/10.3390/nu11051076openalex-snapshotNutritional Modulation of Immune and Central Nervous System Homeostasis: The Role of Diet in Development of Neuroinflammation and Neurological Disease
inferred← citeshttps://doi.org/10.64898/2026.04.30.721942openalex-snapshotAn ancient cis- element regulates translation of arginine decarboxylase to control downstream polyamine biosynthesis and stress responses
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