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Targeted delivery of miRNA therapeutics for cardiovascular diseases: opportunities and challenges

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Multifunctional siRNA delivery system: Polyelectrolyte complex micelles of six‐arm PEG conjugate of siRNA and cell penetrating peptide with crosslinked fusogenic peptide
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Development and optimization of a process for automated recovery of single cells identified by microengraving
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Efficient suppression of murine intracellular adhesion molecule-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation
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MicroRNAs as gatekeepers of apoptosis
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Sonoporation mediated transduction of pDNA/siRNA into joint synovium in vivo
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Targeted Delivery of Nanoparticles Bearing Fibroblast Growth Factor‐2 by Ultrasonic Microbubble Destruction for Therapeutic Arteriogenesis
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Polymer Nanoneedle‐Mediated Intracellular Drug Delivery
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Adeno-Associated Virus
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AAV-Mediated Liver-Directed Gene Therapy
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microRNA-1 enhances the angiogenic differentiation of human cardiomyocyte progenitor cells
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Control of cardiovascular differentiation by microRNAs
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Tat-Conjugated PAMAM Dendrimers as Delivery Agents for Antisense and siRNA Oligonucleotides
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The Development and Mechanism Studies of Cationic Chitosan-Modified Biodegradable PLGA Nanoparticles for Efficient siRNA Drug Delivery
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Bioreducible Crosslinked Polyelectrolyte Complexes for MMP-2 siRNA Delivery into Human Vascular Smooth Muscle Cells
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MicroRNAs in Cardiac Apoptosis
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Non-viral systemic delivery of siRNA or antisense oligonucleotides targeted to Jun N-terminal kinase 1 prevents cellular hypoxic damage
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Microbubbles in ultrasound-triggered drug and gene delivery
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Approaches for the preparation of non-linear amphiphilic polymers and their applications to drug delivery
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The microRNA miR-132 targets Lrrfip1 to block vascular smooth muscle cell proliferation and neointimal hyperplasia
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A novel method for the intracellular delivery of siRNA using microbubble-enhanced focused ultrasound
inferredcites →https://doi.org/10.1016/j.bbrc.2005.08.052openalex-snapshot
Sonoporation using microbubble BR14 promotes pDNA/siRNA transduction to murine heart
inferredcites →https://doi.org/10.1016/j.biomaterials.2011.03.010openalex-snapshot
Excess polycation mediates efficient chitosan-based gene transfer by promoting lysosomal release of the polyplexes
inferredcites →https://doi.org/10.1016/j.biomaterials.2011.04.047openalex-snapshot
Endosomal escape and the knockdown efficiency of liposomal-siRNA by the fusogenic peptide shGALA
inferredcites →https://doi.org/10.1016/j.biomaterials.2011.09.061openalex-snapshot
Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors
inferredcites →https://doi.org/10.1016/j.biomaterials.2012.02.041openalex-snapshot
A mPEG-PLGA-b-PLL copolymer carrier for adriamycin and siRNA delivery
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Enhancing in vivo circulation and siRNA delivery with biodegradable polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol) copolymers
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Delivery of Nox2-NADPH oxidase siRNA with polyketal nanoparticles for improving cardiac function following myocardial infarction
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An LNA-based loss-of-function assay for micro-RNAs
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Human RISC Couples MicroRNA Biogenesis and Posttranscriptional Gene Silencing
inferredcites →https://doi.org/10.1016/j.cell.2007.05.056openalex-snapshot
Drosophila microRNAs Are Sorted into Functionally Distinct Argonaute Complexes after Production by Dicer-1
inferredcites →https://doi.org/10.1016/j.cell.2008.07.020openalex-snapshot
Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/j.cell.2012.03.029openalex-snapshot
A Cardiac MicroRNA Governs Systemic Energy Homeostasis by Regulation of MED13
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MicroRNA Biogenesis: Drosha Can't Cut It without a Partner
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Role of MicroRNA-214 in ginsenoside-Rg1-induced angiogenesis
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MicroRNA‐21 mediates the rapamycin‐induced suppression of endothelial proliferation and migration
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Regulation of cardiac and renal ischemia–reperfusion injury by microRNAs
inferredcites →https://doi.org/10.1016/j.gene.2005.12.031openalex-snapshot
LNA-modified oligonucleotides mediate specific inhibition of microRNA function
inferredcites →https://doi.org/10.1016/j.jconrel.2006.07.021openalex-snapshot
Development and characterisation of chitosan nanoparticles for siRNA delivery
inferredcites →https://doi.org/10.1016/j.jconrel.2009.06.008openalex-snapshot
A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo
inferredcites →https://doi.org/10.1016/j.jconrel.2009.06.019openalex-snapshot
Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery
inferredcites →https://doi.org/10.1016/j.jconrel.2009.08.026openalex-snapshot
Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy
inferredcites →https://doi.org/10.1016/j.jconrel.2009.12.007openalex-snapshot
Grafting of poly(ethylene glycol) to poly-lysine augments its lifetime in blood circulation and accumulation in tumors without loss of the ability to associate with siRNA
inferredcites →https://doi.org/10.1016/j.jconrel.2010.04.005openalex-snapshot
Pegylated poly-l-arginine derivatives of chitosan for effective delivery of siRNA
inferredcites →https://doi.org/10.1016/j.jconrel.2010.11.004openalex-snapshot
Endosomal escape pathways for delivery of biologicals
inferredcites →https://doi.org/10.1016/j.jconrel.2011.02.016openalex-snapshot
Molecular modeling and in vivo imaging can identify successful flexible triazine dendrimer-based siRNA delivery systems
inferredcites →https://doi.org/10.1016/j.jconrel.2011.08.023openalex-snapshot
Biophysical properties of chitosan/siRNA polyplexes: Profiling the polymer/siRNA interactions and bioactivity
inferredcites →https://doi.org/10.1016/j.jconrel.2011.10.009openalex-snapshot
Liposome based systems for systemic siRNA delivery: Stability in blood sets the requirements for optimal carrier design
inferredcites →https://doi.org/10.1016/j.jconrel.2012.01.015openalex-snapshot
Biodegradable copolymers with identical cationic segments and their performance in siRNA delivery
inferredcites →https://doi.org/10.1016/j.jconrel.2012.08.030openalex-snapshot
Efficient reduction of serum cholesterol by combining a liver-targeted gene delivery system with chemically modified apolipoprotein B siRNA
inferredcites →https://doi.org/10.1016/j.jconrel.2013.02.031openalex-snapshot
Anti-apoptotic cardioprotective effects of SHP-1 gene silencing against ischemia–reperfusion injury: Use of deoxycholic acid-modified low molecular weight polyethyleneimine as a cardiac siRNA-carrier
inferredcites →https://doi.org/10.1016/j.jmb.2005.03.013openalex-snapshot
Induction of Inflammatory Cytokines and Interferon Responses by Double-stranded and Single-stranded siRNAs is Sequence-dependent and Requires Endosomal Localization
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Microbubble-enhanced ultrasound to deliver an antisense oligodeoxynucleotide targeting the human androgen receptor into prostate tumours
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Synergistic effects of cell-penetrating peptide Tat and fusogenic peptide HA2-enhanced cellular internalization and gene transduction of organosilica nanoparticles
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Microbubble Stability is a Major Determinant of the Efficiency of Ultrasound and Microbubble Mediated in vivo Gene Transfer
inferredcites →https://doi.org/10.1016/j.ultrasmedbio.2010.05.014openalex-snapshot
Analysis of in vitro Transfection by Sonoporation Using Cationic and Neutral Microbubbles
inferredcites →https://doi.org/10.1016/j.yjmcc.2012.01.020openalex-snapshot
miR-1 mediated suppression of Sorcin regulates myocardial contractility through modulation of Ca2+ signaling
inferredcites →https://doi.org/10.1016/j.yjmcc.2012.07.016openalex-snapshot
A new method of ultrasonic nonviral gene delivery to the adult myocardium
inferredcites →https://doi.org/10.1016/j.yjmcc.2012.08.024openalex-snapshot
MicroRNA-204 is required for differentiation of human-derived cardiomyocyte progenitor cells
inferredcites →https://doi.org/10.1016/j.ymeth.2007.04.004openalex-snapshot
Detection of microRNAs by Northern blot analyses using LNA probes
inferredcites →https://doi.org/10.1016/s0065-2660(05)54001-xopenalex-snapshot
The Mechanism of Naked DNA Uptake and Expression
inferredcites →https://doi.org/10.1016/s0301-5629(03)00976-1openalex-snapshot
Targeted tissue transfection with ultrasound destruction of plasmid-bearing cationic microbubbles
inferredcites →https://doi.org/10.1021/bm201746topenalex-snapshot
Sterically Polymer-Based Liposomal Complexes with Dual-Shell Structure for Enhancing the siRNA Delivery
inferredcites →https://doi.org/10.1021/mp100067uopenalex-snapshot
STAT3 Silencing in Dendritic Cells by siRNA Polyplexes Encapsulated in PLGA Nanoparticles for the Modulation of Anticancer Immune Response
inferredcites →https://doi.org/10.1021/mp300188fopenalex-snapshot
Folate-PEG-Appended Dendrimer Conjugate with α-Cyclodextrin as a Novel Cancer Cell-Selective siRNA Delivery Carrier
inferredcites →https://doi.org/10.1021/mp9000124openalex-snapshot
Synthesis and Biological Evaluation of a Bioresponsive and Endosomolytic siRNA−Polymer Conjugate
inferredcites →https://doi.org/10.1038/35078107openalex-snapshot
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
inferredcites →https://doi.org/10.1038/ajh.2011.116openalex-snapshot
MicroRNA-130a Mediates Proliferation of Vascular Smooth Muscle Cells in Hypertension
inferredcites →https://doi.org/10.1038/gt.2008.135openalex-snapshot
Gene delivery into ischemic myocardium by double-targeted lipoplexes with anti-myosin antibody and TAT peptide
inferredcites →https://doi.org/10.1038/gt.2010.141openalex-snapshot
microRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors
inferredcites →https://doi.org/10.1038/gt.2010.44openalex-snapshot
Heart-targeted adeno-associated viral vectors selected by in vivo biopanning of a random viral display peptide library
inferredcites →https://doi.org/10.1038/gt.2013.16openalex-snapshot
Adeno-associated virus serotype 9 efficiently targets ischemic skeletal muscle following systemic delivery
inferredcites →https://doi.org/10.1038/jcbfm.2010.155openalex-snapshot
Noninvasive and Localized Blood—Brain Barrier Disruption using Focused Ultrasound can be Achieved at Short Pulse Lengths and Low Pulse Repetition Frequencies
inferredcites →https://doi.org/10.1038/mt.2009.91openalex-snapshot
The Effect of Chemical Modification and Nanoparticle Formulation on Stability and Biodistribution of siRNA in Mice
inferredcites →https://doi.org/10.1038/mt.2012.167openalex-snapshot
Cerebral Infusion of AAV9 Vector-encoding Non-self Proteins Can Elicit Cell-mediated Immune Responses
inferredcites →https://doi.org/10.1038/mt.2013.89openalex-snapshot
Local Inhibition of MicroRNA-24 Improves Reparative Angiogenesis and Left Ventricle Remodeling and Function in Mice With Myocardial Infarction
inferredcites →https://doi.org/10.1038/nature03868openalex-snapshot
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
inferredcites →https://doi.org/10.1038/nature04303openalex-snapshot
Silencing of microRNAs in vivo with ‘antagomirs’
inferredcites →https://doi.org/10.1038/nature06783openalex-snapshot
LNA-mediated microRNA silencing in non-human primates
inferredcites →https://doi.org/10.1038/nature07242openalex-snapshot
The impact of microRNAs on protein output
inferredcites →https://doi.org/10.1038/nature07511openalex-snapshot
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
inferredcites →https://doi.org/10.1038/nature09267openalex-snapshot
Mammalian microRNAs predominantly act to decrease target mRNA levels
inferredcites →https://doi.org/10.1038/nature11739openalex-snapshot
Functional screening identifies miRNAs inducing cardiac regeneration
inferredcites →https://doi.org/10.1038/nature11919openalex-snapshot
MicroRNA-34a regulates cardiac ageing and function
inferredcites →https://doi.org/10.1038/nbt.1515openalex-snapshot
Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes
inferredcites →https://doi.org/10.1038/nbt.1989openalex-snapshot
Therapeutic siRNA silencing in inflammatory monocytes in mice
inferredcites →https://doi.org/10.1038/nbt1081openalex-snapshot
Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
inferredcites →https://doi.org/10.1038/ncb0309-228openalex-snapshot
Many roads to maturity: microRNA biogenesis pathways and their regulation
inferredcites →https://doi.org/10.1038/ncb1596openalex-snapshot
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
inferredcites →https://doi.org/10.1038/ncb2126openalex-snapshot
MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling
inferredcites →https://doi.org/10.1038/ncb2210openalex-snapshot
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
inferredcites →https://doi.org/10.1038/ncb2866openalex-snapshot
Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure
inferredcites →https://doi.org/10.1038/ncomms2090openalex-snapshot
The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy
inferredcites →https://doi.org/10.1038/ng1725openalex-snapshot
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation
inferredcites →https://doi.org/10.1038/nm.2617openalex-snapshot
A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy
inferredcites →https://doi.org/10.1038/nm1582openalex-snapshot
MicroRNA-133 controls cardiac hypertrophy
inferredcites →https://doi.org/10.1038/nmeth843openalex-snapshot
In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes
inferredcites →https://doi.org/10.1038/nrcardio.2011.38openalex-snapshot
Innate immune signaling in cardiac ischemia
inferredcites →https://doi.org/10.1038/nrd2742openalex-snapshot
Knocking down barriers: advances in siRNA delivery
inferredcites →https://doi.org/10.1038/nrd3864openalex-snapshot
MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles
inferredcites →https://doi.org/10.1038/nrg2843openalex-snapshot
The widespread regulation of microRNA biogenesis, function and decay
inferredcites →https://doi.org/10.1038/nrm1644openalex-snapshot
MicroRNA biogenesis: coordinated cropping and dicing
inferredcites →https://doi.org/10.1038/nsmb.2293openalex-snapshot
Efficiency and specificity in microRNA biogenesis
inferredcites →https://doi.org/10.1038/sj.gt.3302777openalex-snapshot
A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium
inferredcites →https://doi.org/10.1038/sj.gt.3302778openalex-snapshot
RNA interference in the mouse vascular endothelium by systemic administration of siRNA-lipoplexes for cancer therapy
inferredcites →https://doi.org/10.1056/nejmoa1208760openalex-snapshot
Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis
inferredcites →https://doi.org/10.1056/nejmoa1209026openalex-snapshot
Treatment of HCV Infection by Targeting MicroRNA
inferredcites →https://doi.org/10.1073/pnas.0710228105openalex-snapshot
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure
inferredcites →https://doi.org/10.1073/pnas.0804597105openalex-snapshot
Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis
inferredcites →https://doi.org/10.1073/pnas.0805038105openalex-snapshot
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
inferredcites →https://doi.org/10.1073/pnas.1019055108openalex-snapshot
Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
inferredcites →https://doi.org/10.1073/pnas.1105254108openalex-snapshot
Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23∼27∼24 clusters
inferredcites →https://doi.org/10.1073/pnas.1208863110openalex-snapshot
Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family
inferredcites →https://doi.org/10.1073/pnas.1220038110openalex-snapshot
pH (low) insertion peptide (pHLIP) targets ischemic myocardium
inferredcites →https://doi.org/10.1074/jbc.m112.351791openalex-snapshot
DiGeorge Syndrome Critical Region 8 (DGCR8) Protein-mediated microRNA Biogenesis Is Essential for Vascular Smooth Muscle Cell Development in Mice
inferredcites →https://doi.org/10.1074/jbc.m112.364414openalex-snapshot
Vascular Endothelial Cell-specific MicroRNA-15a Inhibits Angiogenesis in Hindlimb Ischemia
inferredcites →https://doi.org/10.1089/hum.2008.123openalex-snapshot
Adeno-Associated Virus (AAV) Serotype 9 Provides Global Cardiac Gene Transfer Superior to AAV1, AAV6, AAV7, and AAV8 in the Mouse and Rat
inferredcites →https://doi.org/10.1089/hum.2009.182openalex-snapshot
Prevalence of Serum IgG and Neutralizing Factors Against Adeno-Associated Virus (AAV) Types 1, 2, 5, 6, 8, and 9 in the Healthy Population: Implications for Gene Therapy Using AAV Vectors
inferredcites →https://doi.org/10.1089/nat.2011.0293openalex-snapshot
Polymers in Small-Interfering RNA Delivery
inferredcites →https://doi.org/10.1089/oli.2010.0235openalex-snapshot
Efficient Gene Silencing in Lungs and Liver Using Imidazole-Modified Chitosan As a Nanocarrier for Small Interfering RNA
inferredcites →https://doi.org/10.1089/oli.2011.0278openalex-snapshot
PEI- g -PEG-RGD/Small Interference RNA Polyplex-Mediated Silencing of Vascular Endothelial Growth Factor Receptor and Its Potential as an Anti-Angiogenic Tumor Therapeutic Strategy
inferredcites →https://doi.org/10.1093/cvr/cvs003openalex-snapshot
MicroRNA-214 inhibits angiogenesis by targeting Quaking and reducing angiogenic growth factor release
inferredcites →https://doi.org/10.1093/nar/22.22.4681openalex-snapshot
Imporved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide
inferredcites →https://doi.org/10.1093/nar/gkm024openalex-snapshot
Specificity, duplex degradation and subcellular localization of antagomirs
inferredcites →https://doi.org/10.1093/nar/gkq167openalex-snapshot
A dictionary on microRNAs and their putative target pathways
inferredcites →https://doi.org/10.1093/nar/gkr148openalex-snapshot
Analysis of microRNA turnover in mammalian cells following Dicer1 ablation
inferredcites →https://doi.org/10.1093/nar/gnh140openalex-snapshot
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
inferredcites →https://doi.org/10.1093/protein/gzh055openalex-snapshot
Novel RGD lipopeptides for the targeting of liposomes to integrin-expressing endothelial and melanoma cells
inferredcites →https://doi.org/10.1101/gad.1158803openalex-snapshot
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
inferredcites →https://doi.org/10.1101/gad.1334005openalex-snapshot
Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila
inferredcites →https://doi.org/10.1111/j.1582-4934.2010.01104.xopenalex-snapshot
MicroRNA-155 prevents necrotic cell death in human cardiomyocyte progenitor cells via targeting RIP1
inferredcites →https://doi.org/10.1111/j.1742-4658.2011.08090.xopenalex-snapshot
MicroRNAs and cardiovascular diseases
inferredcites →https://doi.org/10.1126/science.1139089openalex-snapshot
Control of Stress-Dependent Cardiac Growth and Gene Expression by a MicroRNA
inferredcites →https://doi.org/10.1126/science.1174381openalex-snapshot
MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice
inferredcites →https://doi.org/10.1126/scitranslmed.3002097openalex-snapshot
Cardiac AAV9-S100A1 Gene Therapy Rescues Post-Ischemic Heart Failure in a Preclinical Large Animal Model
inferredcites →https://doi.org/10.1155/2013/593517openalex-snapshot
MicroRNAs in Cardiovascular Regenerative Medicine: Directing Tissue Repair and Cellular Differentiation
inferredcites →https://doi.org/10.1158/0008-5472.can-11-4079openalex-snapshot
Ultrasound-Targeted Microbubble Destruction to Deliver siRNA Cancer Therapy
inferredcites →https://doi.org/10.1158/1078-0432.ccr-04-1049openalex-snapshot
Antitumor Activity of Small Interfering RNA/Cationic Liposome Complex in Mouse Models of Cancer
inferredcites →https://doi.org/10.1158/1078-0432.ccr-10-0005openalex-snapshot
Targeted Gene Silencing Using RGD-Labeled Chitosan Nanoparticles
inferredcites →https://doi.org/10.1161/atvbaha.109.197434openalex-snapshot
MicroRNA-1 and -499 Regulate Differentiation and Proliferation in Human-Derived Cardiomyocyte Progenitor Cells
inferredcites →https://doi.org/10.1161/atvbaha.109.200873openalex-snapshot
MicroRNAs Are Necessary for Vascular Smooth Muscle Growth, Differentiation, and Function
inferredcites →https://doi.org/10.1161/circresaha.108.182535openalex-snapshot
miR-133 and miR-30 Regulate Connective Tissue Growth Factor
inferredcites →https://doi.org/10.1161/circresaha.108.183806openalex-snapshot
Ultrasound and Microbubble-Targeted Delivery of Macromolecules Is Regulated by Induction of Endocytosis and Pore Formation
inferredcites →https://doi.org/10.1161/circresaha.109.200451openalex-snapshot
Loss of Cardiac microRNA-Mediated Regulation Leads to Dilated Cardiomyopathy and Heart Failure
inferredcites →https://doi.org/10.1161/circresaha.111.243394openalex-snapshot
MicroRNAs and Stem Cells
inferredcites →https://doi.org/10.1161/circresaha.111.244442openalex-snapshot
Inhibition of miR-15 Protects Against Cardiac Ischemic Injury
inferredcites →https://doi.org/10.1161/circresaha.111.300418openalex-snapshot
MicroRNA-15a and MicroRNA-16 Impair Human Circulating Proangiogenic Cell Functions and Are Increased in the Proangiogenic Cells and Serum of Patients With Critical Limb Ischemia
inferredcites →https://doi.org/10.1161/circresaha.112.300658openalex-snapshot
mir-17–92 Cluster Is Required for and Sufficient to Induce Cardiomyocyte Proliferation in Postnatal and Adult Hearts
inferredcites →https://doi.org/10.1161/circresaha.112.300682openalex-snapshot
MicroRNA-22 Regulates Cardiac Hypertrophy and Remodeling in Response to Stress
inferredcites →https://doi.org/10.1161/circresaha.112.300806openalex-snapshot
In Vivo Suppression of MicroRNA-24 Prevents the Transition Toward Decompensated Hypertrophy in Aortic-Constricted Mice
inferredcites →https://doi.org/10.1161/circulationaha.109.889048openalex-snapshot
MicroRNAs Add a New Dimension to Cardiovascular Disease
inferredcites →https://doi.org/10.1161/circulationaha.110.000323openalex-snapshot
MicroRNA-100 Regulates Neovascularization by Suppression of Mammalian Target of Rapamycin in Endothelial and Vascular Smooth Muscle Cells
inferredcites →https://doi.org/10.1161/circulationaha.110.958967openalex-snapshot
MicroRNA-328 Contributes to Adverse Electrical Remodeling in Atrial Fibrillation
inferredcites →https://doi.org/10.1161/circulationaha.111.030932openalex-snapshot
Therapeutic Inhibition of miR-208a Improves Cardiac Function and Survival During Heart Failure
inferredcites →https://doi.org/10.1161/circulationaha.111.039008openalex-snapshot
MicroRNA-24 Regulates Vascularity After Myocardial Infarction
inferredcites →https://doi.org/10.1161/circulationaha.112.000116openalex-snapshot
Monocyte-Directed RNAi Targeting CCR2 Improves Infarct Healing in Atherosclerosis-Prone Mice
inferredcites →https://doi.org/10.1161/circulationaha.112.000882openalex-snapshot
MiR-378 Controls Cardiac Hypertrophy by Combined Repression of Mitogen-Activated Protein Kinase Pathway Factors
inferredcites →https://doi.org/10.1161/circulationaha.112.094524openalex-snapshot
MicroRNA-101 Inhibited Postinfarct Cardiac Fibrosis and Improved Left Ventricular Compliance via the FBJ Osteosarcoma Oncogene/Transforming Growth Factor-β1 Pathway
inferredcites →https://doi.org/10.1161/circulationaha.113.001904openalex-snapshot
Inhibition of MicroRNA-92a Protects Against Ischemia/Reperfusion Injury in a Large-Animal Model
inferredcites →https://doi.org/10.1172/jci36154openalex-snapshot
MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice
inferredcites →https://doi.org/10.1172/jci59327openalex-snapshot
MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca2+ overload and cell death
inferredcites →https://doi.org/10.1186/gb-2011-12-12-r126openalex-snapshot
MicroRNAs and their isomiRs function cooperatively to target common biological pathways
inferredcites →https://doi.org/10.1194/jlr.m012872openalex-snapshot
siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids
inferredcites →https://doi.org/10.1242/dev.029736openalex-snapshot
Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126
inferredcites →https://doi.org/10.1242/jcs.099200openalex-snapshot
MicroRNAs and their roles in aging
inferredcites →https://doi.org/10.1261/rna.5167604openalex-snapshot
Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
inferredcites →https://doi.org/10.1261/rna.5235104openalex-snapshot
Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing
inferredcites →https://doi.org/10.1261/rna.844108openalex-snapshot
miR-122 targeting with LNA/2′-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA–peptide conjugates
inferredcites →https://doi.org/10.1371/journal.pbio.0020098openalex-snapshot
Sequence-Specific Inhibition of Small RNA Function
inferredcites →https://doi.org/10.1371/journal.pone.0044138openalex-snapshot
A Novel In Vivo siRNA Delivery System Specifically Targeting Liver Cells for Protection of ConA-Induced Fulminant Hepatitis
inferredcites →https://doi.org/10.1371/journal.pone.0055214openalex-snapshot
On Measuring miRNAs after Transient Transfection of Mimics or Antisense Inhibitors
inferredcites →https://doi.org/10.1373/clinchem.2009.141580openalex-snapshot
Robust MicroRNA Stability in Degraded RNA Preparations from Human Tissue and Cell Samples
inferredcites →https://doi.org/10.2147/ijn.s17040openalex-snapshot
Research progress on siRNA delivery with nonviral carriers
inferredcites →https://doi.org/10.2147/ijn.s32900openalex-snapshot
An MRI-visible non-viral vector for targeted Bcl-2 siRNA delivery to neuroblastoma
inferredcites →https://doi.org/10.2174/138955709787316029openalex-snapshot
The Potential of Modulating Small RNA Activity In Vivo
inferredcites →https://doi.org/10.2174/15701611113119990129openalex-snapshot
Role, Function and Therapeutic Potential of microRNAs in Vascular Aging
inferredcites →https://doi.org/10.5414/cpp50076openalex-snapshot
Phase I clinical development of Atu027, a siRNA formulation targeting PKN3 in patients with advanced solid tumors

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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MiR-203 is an Anti-Obese miRNA by Targeting ASBT
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Nanomedicine Approaches for Advanced Diagnosis and Treatment of Atherosclerosis and Related Ischemic Diseases
inferred← citeshttps://doi.org/10.1007/16833_2024_201openalex-snapshot
Controlled Delivery of Target-Specific MicroRNA Analogs as a Key to RNAi Therapeutics in Cancer
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An Overview of Non-coding RNAs and Cardiovascular System
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Translational Potential of Non-coding RNAs for Cardiovascular Disease
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Non-coding RNAs in Cardiac Regeneration
inferred← citeshttps://doi.org/10.1007/s10528-024-10852-zopenalex-snapshot
miR-146b-5p Regulates the Enteric Nervous System Development in Hirschsprung Disease via Targeting RET Pathway
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RNA interference-based therapy and its delivery systems
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MicroRNA delivery based on nanoparticles of cardiovascular diseases
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Management of oxidative stress and inflammation in cardiovascular diseases: mechanisms and challenges
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The role of circular RNAs as miRNA sponges in the mechanisms and therapeutic potential of triple negative breast cancer
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MicroRNAs and Long Non-coding RNAs in Genetic Diseases
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MicroRNA-based nanomedicine for the treatment of head and neck cancer
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Redox nanotherapeutics: Fundamentals and applications
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Repairing the heart: State-of the art delivery strategies for biological therapeutics
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High inorganic phosphate concentration inhibits osteoclastogenesis by modulating miR-223
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microRNAs in the pathophysiology of CKD-MBD: Biomarkers and innovative drugs
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Achieving successful delivery of oligonucleotides — From physico-chemical characterization to in vivo evaluation
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MMISH: Multicolor microRNA in situ hybridization for paraffin embedded samples
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2019.118789openalex-snapshot
Efficient delivery of anti-miR-210 using Tachyplesin, a cell penetrating peptide, for glioblastoma treatment
inferred← citeshttps://doi.org/10.1016/j.isci.2022.104708openalex-snapshot
MiR-203 is an anti-obese microRNA by targeting apical sodium-dependent bile acid transporter
inferred← citeshttps://doi.org/10.1021/acsami.6b13295openalex-snapshot
A Neutralized Noncharged Polyethylenimine-Based System for Efficient Delivery of siRNA into Heart without Toxicity
inferred← citeshttps://doi.org/10.1038/s41434-020-00197-8openalex-snapshot
Gene therapy and gene correction: targets, progress, and challenges for treating human diseases
inferred← citeshttps://doi.org/10.1038/s41598-021-95234-wopenalex-snapshot
Plasma expression of microRNA-425-5p and microRNA-451a as biomarkers of cardiovascular disease in rheumatoid arthritis patients
inferred← citeshttps://doi.org/10.1039/c5mb00806aopenalex-snapshot
The regulatory function of microRNA-1 in arrhythmias
inferred← citeshttps://doi.org/10.1042/bst20170037openalex-snapshot
MicroRNA-based therapeutics in cardiovascular disease: screening and delivery to the target
inferred← citeshttps://doi.org/10.1080/17460441.2017.1263298openalex-snapshot
MicroRNA-targeted therapeutics for lung cancer treatment
inferred← citeshttps://doi.org/10.1080/26895293.2023.2255753openalex-snapshot
Experimental validation and bioinformatics analysis of hub genes in myocardial infarction
inferred← citeshttps://doi.org/10.1089/ars.2017.7328openalex-snapshot
MicroRNAs Regulating Reactive Oxygen Species in Cardiovascular Diseases
inferred← citeshttps://doi.org/10.1093/cvr/cvaa137openalex-snapshot
Stimulating pro-reparative immune responses to prevent adverse cardiac remodelling: consensus document from the joint 2019 meeting of the ESC Working Groups of cellular biology of the heart and myocardial function
inferred← citeshttps://doi.org/10.1093/rheumatology/keac483openalex-snapshot
A panel of plasma microRNAs improves the assessment of surrogate markers of cardiovascular disease in rheumatoid arthritis patients
inferred← citeshttps://doi.org/10.1097/cm9.0000000000002080openalex-snapshot
Role of epigenetic abnormalities and intervention in obstructive sleep apnea target organs
inferred← citeshttps://doi.org/10.1097/in9.0000000000000027openalex-snapshot
The role of extracellular vesicle-derived miRNAs in adipose tissue function and metabolic health
inferred← citeshttps://doi.org/10.1111/jcmm.12586openalex-snapshot
Micro RNA ‐132/212 family enhances arteriogenesis after hindlimb ischaemia through modulation of the Ras‐ MAPK pathway
inferred← citeshttps://doi.org/10.1155/2017/9158572openalex-snapshot
The Management of Cardiovascular Risk through Epigenetic Biomarkers
inferred← citeshttps://doi.org/10.1159/000450774openalex-snapshot
MicroRNAs Are Associated with Uremic Toxicity, Cardiovascular Calcification, and Disease
inferred← citeshttps://doi.org/10.1161/atvbaha.117.309233openalex-snapshot
The Involvement of miRNA in Carotid-Related Stroke
inferred← citeshttps://doi.org/10.1161/circresaha.116.310215openalex-snapshot
MicroRNAs
inferred← citeshttps://doi.org/10.1177/0960327120926254openalex-snapshot
MicroRNA: Potential biomarker and target of therapy in acute lung injury
inferred← citeshttps://doi.org/10.1186/1471-2164-15-s9-s16openalex-snapshot
Rule discovery and distance separation to detect reliable miRNA biomarkers for the diagnosis of lung squamous cell carcinoma
inferred← citeshttps://doi.org/10.1186/s11658-019-0196-3openalex-snapshot
Editorial focus: understanding off-target effects as the key to successful RNAi therapy
inferred← citeshttps://doi.org/10.20517/2394-4722.2019.18openalex-snapshot
Peptide nucleic acid-based targeting of microRNAs: possible therapeutic applications for glioblastoma
inferred← citeshttps://doi.org/10.21037/ncri.2018.07.04openalex-snapshot
Induction of cardiomyocyte proliferation, a new way forward for true myocardial regeneration?
inferred← citeshttps://doi.org/10.2147/ijn.s126310openalex-snapshot
Low-density lipoprotein-coupled micelles with reduction and pH dual sensitivity for intelligent co-delivery of paclitaxel and siRNA to breast tumor
inferred← citeshttps://doi.org/10.2174/1389202916999150120153344openalex-snapshot
Heart Failure in Chronic Myocarditis: A Role for microRNAs?
inferred← citeshttps://doi.org/10.2174/1389557519666190312161551openalex-snapshot
Follistatin-like 1 in Cardiovascular Disease and Inflammation
inferred← citeshttps://doi.org/10.31083/j.rcm.2020.01.577openalex-snapshot
Potential roles of microRNA-1 and microRNA-133 in cardiovascular disease
inferred← citeshttps://doi.org/10.3389/fbioe.2019.00489openalex-snapshot
Application of the Nano-Drug Delivery System in Treatment of Cardiovascular Diseases
inferred← citeshttps://doi.org/10.3389/fcvm.2021.592362openalex-snapshot
miR-132/212 Impairs Cardiomyocytes Contractility in the Failing Heart by Suppressing SERCA2a
inferred← citeshttps://doi.org/10.3389/fcvm.2021.716213openalex-snapshot
Roles of MicroRNAs in Glucose and Lipid Metabolism in the Heart
inferred← citeshttps://doi.org/10.3389/fgene.2015.00074openalex-snapshot
A snapshot of genetic and epigenetic basis of arrhythmia and heart failure
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Advances in vitiligo: Update on therapeutic targets
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MicroRNA Targeting to Modulate Tumor Microenvironment
inferred← citeshttps://doi.org/10.3389/fphar.2021.751487openalex-snapshot
Advances in miR-132-Based Biomarker and Therapeutic Potential in the Cardiovascular System
inferred← citeshttps://doi.org/10.3389/fphys.2020.00590openalex-snapshot
Loss of miR-132/212 Has No Long-Term Beneficial Effect on Cardiac Function After Permanent Coronary Occlusion in Mice
inferred← citeshttps://doi.org/10.3390/cancers12113119openalex-snapshot
The Effects of Single Nucleotide Polymorphisms in Cancer RNAi Therapies
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miRacle of microRNA-Driven Cancer Nanotherapeutics
inferred← citeshttps://doi.org/10.3390/cancers15112903openalex-snapshot
HIF-1-Induced hsa-miR-429: Understanding Its Direct Targets as the Key to Developing Cancer Diagnostics and Therapies
inferred← citeshttps://doi.org/10.3390/ijms17040502openalex-snapshot
MicroRNA and Heart Failure
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A MicroRNA Perspective on Cardiovascular Development and Diseases: An Update
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Encapsulation of miRNA and siRNA into Nanomaterials for Cancer Therapeutics
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Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: New trends in the development of miRNA therapeutic strategies in oncology (Review)
inferred← citeshttps://doi.org/10.3892/mmr.2018.8498openalex-snapshot
SLC35E3 identified as a target of novel‑m1061‑5p via microRNA profiling of patients with cardiovascular disease
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Targeting and modulation of the tumor stroma in pancreatic cancer
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miRNA Therapeutics: A New Class of Drugs with Potential Therapeutic Applications in the Heart
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Therapeutic Implication of miRNA in Human Disease
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MicroARNs, marqueurs de la pathologie valvulaire aortique
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Ultrasound and Microbubble-targeted Delivery of a microRNA Inhibitor to the Heart Suppresses Cardiac Hypertrophy and Preserves Cardiac Function
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The Role of Circulating MicroRNAs in Cardiovascular Diseases: A Novel Biomarker for Diagnosis and Potential Therapeutic Targets?
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