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Kidney, heart and brain: three organs targeted by ageing and glycation
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1 of the 200 references listed on this page is in the Retraction Watch database as retracted (export 2026-11-04): 10.1111/j.1582-4934.2008.00547.x (notice 2023-05-07).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/cpt.148openalex-snapshotEmerging Targets for Therapeutic Development in Diabetes and Its Complications: The RAGE Signaling Pathway
inferredcites →https://doi.org/10.1002/hep.20045openalex-snapshotBlockade of receptor for advanced glycation end product (RAGE) attenuates ischemia and reperfusion injury to the liver in mice
inferredcites →https://doi.org/10.1002/mnfr.201600140openalex-snapshotQuantitative assessment of organ distribution of dietary protein‐bound 13C‐labeled Nɛ‐carboxymethyllysine after a chronic oral exposure in mice
inferredcites →https://doi.org/10.1007/bf00403957openalex-snapshotRenal fate of circulating advanced glycated end products (AGE): evidence for reabsorption and catabolism of AGE-peptides by renal proximal tubular cells
inferredcites →https://doi.org/10.1007/s00125-007-0687-zopenalex-snapshotIncreased serum levels of advanced glycation endproducts predict total, cardiovascular and coronary mortality in women with type 2 diabetes: a population-based 18 year follow-up study
inferredcites →https://doi.org/10.1007/s00418-010-0706-xopenalex-snapshotCombined immunoelectron microscopic and computer-assisted image analyses to detect advanced glycation end-products in human myocardium
inferredcites →https://doi.org/10.1007/s10719-016-9679-xopenalex-snapshotImplication of advanced glycation end products (Ages) and their receptor (Rage) on myocardial contractile and mitochondrial functions
inferredcites →https://doi.org/10.1007/s11064-015-1814-8openalex-snapshotEffects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-β Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus
inferredcites →https://doi.org/10.1016/j.abb.2015.11.003openalex-snapshotCarboxymethyl lysine induces EMT in podocytes through transcription factor ZEB2: Implications for podocyte depletion and proteinuria in diabetes mellitus
inferredcites →https://doi.org/10.1016/j.ejphar.2016.07.008openalex-snapshotBlockade of receptor for advanced glycation end products protects against systolic overload-induced heart failure after transverse aortic constriction in mice
inferredcites →https://doi.org/10.1016/j.lfs.2006.11.035openalex-snapshotAdvanced glycation endproduct induces ROS accumulation, apoptosis, MAP kinase activation and nuclear O-GlcNAcylation in human cardiac myocytes
inferredcites →https://doi.org/10.1016/j.mce.2014.08.014openalex-snapshotPolydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells
inferredcites →https://doi.org/10.1016/j.mvr.2005.10.001openalex-snapshotVascular endothelial growth factor receptor-2 and low affinity VEGF binding sites on human glomerular endothelial cells: Biological effects and advanced glycosilation end products modulation
inferredcites →https://doi.org/10.1016/j.mvr.2011.01.001openalex-snapshotIrbesartan inhibits advanced glycation end product (AGE)-induced up-regulation of vascular cell adhesion molecule-1 (VCAM-1) mRNA levels in glomerular endothelial cells
inferredcites →https://doi.org/10.1016/j.neurobiolaging.2013.01.012openalex-snapshotAdvanced glycation end-products disrupt the blood–brain barrier by stimulating the release of transforming growth factor–β by pericytes and vascular endothelial growth factor and matrix metalloproteinase–2 by endothelial cells in vitro
inferredcites →https://doi.org/10.1016/s0003-9861(02)00067-xopenalex-snapshotEffect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal
inferredcites →https://doi.org/10.1016/s0197-4580(00)00253-0openalex-snapshotIncreased protein glycation in cerebrospinal fluid of Alzheimer’s disease 2 2Abbreviations: AD, Alzheimer’s disease; AGEs, advanced glycation end products; apo, apolipoprotein; BSA, bovine serum albumin; CSF, cerebrospinal fluid; ELISA, enzyme-linked immunosorbent assay; PBS, phosphate buffer…
inferredcites →https://doi.org/10.1021/bi5013194openalex-snapshotComprehensive Analysis of Maillard Protein Modifications in Human Lenses: Effect of Age and Cataract
inferredcites →https://doi.org/10.1021/jf103116copenalex-snapshotFormation of Arginine Modifications in a Model System of N α - tert -Butoxycarbonyl (Boc)-Arginine with Methylglyoxal
inferredcites →https://doi.org/10.1021/jf302831dopenalex-snapshotResveratrol Upregulates Nrf2 Expression To Attenuate Methylglyoxal-Induced Insulin Resistance in Hep G2 Cells
inferredcites →https://doi.org/10.1021/jf501005nopenalex-snapshotAn Advanced Glycation End Product (AGE)-Rich Diet Promotes Nε-Carboxymethyl-lysine Accumulation in the Cardiac Tissue and Tendons of Rats
inferredcites →https://doi.org/10.1021/jf505063topenalex-snapshotIncreased Accumulation of Protein-BoundNε-(Carboxymethyl)lysine in Tissues of Healthy Rats after Chronic OralNε-(Carboxymethyl)lysine
inferredcites →https://doi.org/10.1038/ki.2012.184openalex-snapshotThe receptor of advanced glycation end products plays a central role in advanced oxidation protein products-induced podocyte apoptosis
inferredcites →https://doi.org/10.1042/bj20030763openalex-snapshotQuantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry
inferredcites →https://doi.org/10.1042/bj3640001openalex-snapshotAssay of advanced glycation endproducts (AGEs): surveying AGEs by chromatographic assay with derivatization by 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and application to N∊-carboxymethyl-lysine- and N∊-(1-carboxyethyl)lysine-modified albumin
inferredcites →https://doi.org/10.1073/pnas.91.20.9441openalex-snapshotModification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency.
inferredcites →https://doi.org/10.1074/jbc.m111.252395openalex-snapshotMuscle Creatine Kinase Deficiency Triggers Both Actin Depolymerization and Desmin Disorganization by Advanced Glycation End Products in Dilated Cardiomyopathy
inferredcites →https://doi.org/10.1074/jbc.m202634200openalex-snapshotAdvanced Glycation End Product-induced Apoptosis and Overexpression of Vascular Endothelial Growth Factor and Monocyte Chemoattractant Protein-1 in Human-cultured Mesangial Cells
inferredcites →https://doi.org/10.1093/brain/awq069openalex-snapshotPowerful beneficial effects of benfotiamine on cognitive impairment and -amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice
inferredcites →https://doi.org/10.1093/cercor/bhh123openalex-snapshotAge- and Stage-dependent Accumulation of Advanced Glycation End Products in Intracellular Deposits in Normal and Alzheimer's Disease Brains
inferredcites →https://doi.org/10.1093/eurjhf/hfp070openalex-snapshotBlockage of Receptor for Advanced Glycation End Products Prevents Development of Cardiac Dysfunction in db/db Type 2 Diabetic Mice
inferredcites →https://doi.org/10.1096/fj.02-1102fjeopenalex-snapshotThe breakdown of pre‐existing advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes
inferredcites →https://doi.org/10.1096/fj.03-1053fjeopenalex-snapshotRAGE‐ and TGF‐ β receptor‐mediated signals converge on STAT5 and p21 waf to control cell‐cycle progression of mesangial cells: a possible role in the development and progression of diabetic nephropathy
inferredcites →https://doi.org/10.1096/fj.08-109033openalex-snapshotA soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane‐bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)
inferredcites →https://doi.org/10.1096/fj.09-139634openalex-snapshotRAGE‐dependent signaling in microglia contributes to neuroinflammation, Aβ accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease
inferredcites →https://doi.org/10.1111/1440-1681.12194openalex-snapshotAdvanced glycation end‐products impair Na+/K+‐ ATP ase activity in diabetic cardiomyopathy: Role of the adenosine monophosphate‐activated protein kinase/sirtuin 1 pathway
inferredcites →https://doi.org/10.1111/nep.12526openalex-snapshotEzrin contributes to impaired podocyte migration and adhesion caused by advanced glycation end products
inferredcites →https://doi.org/10.1155/2015/684242openalex-snapshotAdvanced Glycation End Products Induce Endothelial-to-Mesenchymal Transition via Downregulating Sirt 1 and Upregulating TGF-βin Human Endothelial Cells
inferredcites →https://doi.org/10.1159/000075627openalex-snapshotRandomized Trial of an Inhibitor of Formation of Advanced Glycation End Products in Diabetic Nephropathy
inferredcites →https://doi.org/10.1159/000108104openalex-snapshotEffects of Pyridoxamine in Combined Phase 2 Studies of Patients with Type 1 and Type 2 Diabetes and Overt Nephropathy
inferredcites →https://doi.org/10.1159/000108757openalex-snapshotEffects of Advanced Glycation End Product Modification on Proximal Tubule Epithelial Cell Processing of Albumin
inferredcites →https://doi.org/10.1159/000381464openalex-snapshotHMGB1 Enhances the AGE-Induced Expression of CTGF and TGF-β via RAGE-Dependent Signaling in Renal Tubular Epithelial Cells
inferredcites →https://doi.org/10.1172/jci116552openalex-snapshotIncreased collagen-linked pentosidine levels and advanced glycosylation end products in early diabetic nephropathy.
inferredcites →https://doi.org/10.1172/jci119180openalex-snapshotIncreased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.
inferredcites →https://doi.org/10.1172/jci11951openalex-snapshotAdvanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)
inferredcites →https://doi.org/10.1172/jci119853openalex-snapshotImmunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.
inferredcites →https://doi.org/10.1172/jci58642openalex-snapshotA multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease
inferredcites →https://doi.org/10.1177/0961203312444495openalex-snapshotReceptor for advanced glycation end products (RAGE) polymorphisms are associated with systemic lupus erythematosus and disease severity in lupus nephritis
inferredcites →https://doi.org/10.1186/1475-2840-10-80openalex-snapshotImpact of type 2 diabetes and the metabolic syndrome on myocardial structure and microvasculature of men with coronary artery disease
inferredcites →https://doi.org/10.1186/s12933-016-0343-3openalex-snapshotSkin collagen fluorophore LW-1 versus skin fluorescence as markers for the long-term progression of subclinical macrovascular disease in type 1 diabetes
inferredcites →https://doi.org/10.1196/annals.1333.055openalex-snapshotRenal Effects of Oral Maillard Reaction Product Load in the Form of Bread Crusts in Healthy and Subtotally Nephrectomized Rats
inferredcites →https://doi.org/10.1210/jc.2009-0089openalex-snapshotProtection against Loss of Innate Defenses in Adulthood by Low Advanced Glycation End Products (AGE) Intake: Role of the Antiinflammatory AGE Receptor-1
inferredcites →https://doi.org/10.12659/aot.883223openalex-snapshotAdvanced glycation end product accumulation in the cardiomyocytes of heart failure patients with and without diabetes
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.3897/pharmacia.71.e124801zenodo-depositor-declaredCanagliflozin exerts anti-inflammatory and antioxidant effects in the heart and skin tissues: Biochemical and histopathological assessment in a model of accelerated aging induced by D-galactose in mice
inferred← citeshttps://doi.org/10.1002/jhet.3807openalex-snapshotDual anti‐inflammatory and antiglycation propensities of a potentially novel class of functionalized fluoroquinolones
inferred← citeshttps://doi.org/10.1016/j.bioorg.2026.110044openalex-snapshotShared pathophysiology and therapeutic repurposing in Alzheimer's disease and type 2 diabetes: a critical review of convergent mechanisms and clinical challenges
inferred← citeshttps://doi.org/10.1016/j.cca.2026.121273openalex-snapshotDetermination of pentosidine in fingernails by liquid chromatography with fluorescence detection (LC-FL) – Methodology and association with glycated hemoglobin (HbA1c), skin autofluorescence (SAF) and other ungual glycation biomarkers among people with diabetes.
inferred← citeshttps://doi.org/10.1016/j.exger.2019.110823openalex-snapshotl-Theanine attenuates liver aging by inhibiting advanced glycation end products in d-galactose-induced rats and reversing an imbalance of oxidative stress and inflammation
inferred← citeshttps://doi.org/10.1016/j.jep.2021.114784openalex-snapshotIntegrating network pharmacology and non-targeted metabolomics to explore the common mechanism of Coptis Categorized Formula improving T2DM zebrafish
inferred← citeshttps://doi.org/10.1016/j.phymed.2026.157772openalex-snapshotAdvanced glycation end products (AGEs) and in vitro and in vivo approaches to study their mechanisms of action and the protective properties of natural compounds
inferred← citeshttps://doi.org/10.1038/s41598-026-36667-zopenalex-snapshotOptical coherence tomography and histological assessment of cutaneous vasculature and neural changes in long-term smokers: an exploratory study
inferred← citeshttps://doi.org/10.1080/10408363.2026.2651310openalex-snapshotGlycation and disease: a systematic review of the analytical methods and applications of advanced glycation end products (AGEs) as biomarkers of disease
inferred← citeshttps://doi.org/10.1093/gerona/glae272openalex-snapshotAdvanced Glycation End-Products and Metabolomics Are Independently Associated With Frailty: The Longitudinal Doetinchem Cohort Study
inferred← citeshttps://doi.org/10.1155/2021/8850112openalex-snapshotl ‐Theanine Ameliorates d ‐Galactose‐Induced Brain Damage in Rats via Inhibiting AGE Formation and Regulating Sirtuin1 and BDNF Signaling Pathways
inferred← citeshttps://doi.org/10.21203/rs.3.rs-20659/v1openalex-snapshotThe ability of active fraction from Kappaphycus alvarezii (Doty) Doty Ex.P.C.Silva to Decrease Glucose Levels inhibit advanced Glycation End-Products (AGEs) Formation and RAGE (AGER) Gene Expression in Diabetic Rats
inferred← citeshttps://doi.org/10.2147/ijn.s416202openalex-snapshotArthrospira platensis Nanoparticles Mitigate Aging-Related Oxidative Injured Brain Induced by D-galactose in Rats Through Antioxidants, Anti-Inflammatory, and MAPK Pathways
inferred← citeshttps://doi.org/10.3390/antiox10121916openalex-snapshotCamphorquinone Promotes the Antisenescence Effect via Activating AMPK/SIRT1 in Stem Cells and D-Galactose-Induced Aging Mice
inferred← citeshttps://doi.org/10.3390/antiox7080098openalex-snapshotTargeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review
inferred← citeshttps://doi.org/10.3390/antiox8030073openalex-snapshotProtective Effect of the Hexanic Extract of Eryngium carlinae Inflorescences In Vitro, in Yeast, and in Streptozotocin-Induced Diabetic Male Rats
inferred← citeshttps://doi.org/10.3390/foods12244381openalex-snapshotAgrocybe aegerita Polysaccharide Combined with Bifidobacterium lactis Bb-12 Attenuates Aging-Related Oxidative Stress and Restores Gut Microbiota
inferred← citeshttps://doi.org/10.3390/ijms22136839openalex-snapshotRETRACTED: Thymoquinone and Curcumin Defeat Aging-Associated Oxidative Alterations Induced by D-Galactose in Rats’ Brain and Heart
inferred← citeshttps://doi.org/10.3390/jcm11154419openalex-snapshotParacrine IGF-1 Activates SOD2 Expression and Regulates ROS/p53 Axis in the Treatment of Cardiac Damage in D-Galactose-Induced Aging Rats after Receiving Mesenchymal Stem Cells
inferred← citeshttps://doi.org/10.3390/nu11081748openalex-snapshotThe Modern Western Diet Rich in Advanced Glycation End-Products (AGEs): An Overview of Its Impact on Obesity and Early Progression of Renal Pathology
inferred← citeshttps://doi.org/10.3724/abbs.2023222openalex-snapshotDiscovery of age-related early-stage glycated proteins based on deep quantitative serum glycated proteome analysis
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