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New Sesquiterpene Dimers fromInula britannicaInhibit NF-κB Activation and NO and TNF-α Production in LPS-Stimulated RAW264.7 Cells

https://doi.org/10.1055/s-2005-873189
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Identification of diverse sesquiterpenoids with anti-fibrotic potential from Inula japonica Thunb.
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Selective cytotoxicity, inhibition of cell cycle progression, and induction of apoptosis in human breast cancer cells by sesquiterpenoids from Inula lineariifolia Turcz.
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Differentiation of genuine Inula britannica L. and substitute specimens based on the determination of 15 components using LC–MS/MS and principal components analysis
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Eupatolide, isolated from Liriodendron tulipifera, sensitizes TNF-mediated dual modes of apoptosis and necroptosis by disrupting RIPK1 ubiquitination
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2022.10.008openalex-snapshot
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Britanin suppresses LPS-induced nitric oxide, PGE2 and cytokine production via NF-κB and MAPK inactivation in RAW 264.7 cells
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Nuclear factor kappaB-mediated down-regulation of adhesion molecules: Possible mechanism for inhibitory activity of bigelovin against inflammatory monocytes adhesion to endothelial cells
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Molecular cloning and functional analysis of a 10-epi-junenol synthase from Inula hupehensis
inferred← citeshttps://doi.org/10.1016/j.taap.2014.01.014openalex-snapshot
Sesquiterpene dimmer (DSF-27) inhibits the release of neuroinflammatory mediators from microglia by targeting spleen tyrosine kinase (Syk) and Janus kinase 2 (Jak2): Two major non-receptor tyrosine signaling proteins involved in inflammatory events
inferred← citeshttps://doi.org/10.1016/j.tet.2010.09.091openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.tifs.2019.02.003openalex-snapshot
Recent advances in the development of sesquiterpenoids in the treatment of type 2 diabetes
inferred← citeshttps://doi.org/10.1016/s1875-5364(17)30062-6openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/s1875-5364(25)60931-9openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/s1875-5364(26)61192-2openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.jafc.5b03075openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.jnatprod.4c00269openalex-snapshot
Characterization of Sesquiterpene Dimers from the Flowers of Inula japonica and the Structural Revisions of Related Compounds
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.5b01106openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.jnatprod.6b00810openalex-snapshot
Ochracenes A–I, Humulane-Derived Sesquiterpenoids from the Antarctic Fungus Aspergillus ochraceopetaliformis
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inferred← citeshttps://doi.org/10.1021/np200319xopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/b706427fopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/c0cc03572fopenalex-snapshot
Neojaponicone A, a bioactive sesquiterpene lactone dimer with an unprecedented carbon skeleton from Inula japonica
inferred← citeshttps://doi.org/10.1039/c0np00050gopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/c2ra01014copenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/c4ra11171kopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/c9np00037bopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/d2ob02220fopenalex-snapshot
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inferred← citeshttps://doi.org/10.1080/10286020.2021.1923012openalex-snapshot
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inferred← citeshttps://doi.org/10.1080/14786419.2024.2362967openalex-snapshot
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inferred← citeshttps://doi.org/10.1080/14786419.2026.2658760openalex-snapshot
New sesquiterpenoids from the flowers of Pentanema britannicum with cytotoxicity activities
inferred← citeshttps://doi.org/10.1097/tp.0b013e3181af66faopenalex-snapshot
Sesquiterpenes as Immunosuppressants
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-12-3258openalex-snapshot
Japonicone A Suppresses Growth of Burkitt Lymphoma Cells through Its Effect on NF-κB
inferred← citeshttps://doi.org/10.1201/b10852-27openalex-snapshot
Targeting Inflammatory Pathways by Nutraceuticals for Prevention and Treatment of Arthritis
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Simultaneous Quantification of Six Sesquiterpene Lactones in Inula britannica L. by RP-LC
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TNF: A master switch for inflammation to cancer
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In vitroimmunomodulatory activity andin vivoanti-inflammatory and analgesic potential with gastroprotective effect of the Mediterranean red algaLaurencia obtusa
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inferred← citeshttps://doi.org/10.3390/molecules29143289openalex-snapshot
Inhibitory Effect of Selected Guaianolide and Germacranolide Sesquiterpene Lactones on Nitric Oxide Production
inferred← citeshttps://doi.org/10.3390/molecules29235749openalex-snapshot
Chemical Profile and Biological Properties of Methanolic and Ethanolic Extracts from the Aerial Parts of Inula britannica L. Growing in Central Asia
inferred← citeshttps://doi.org/10.3892/mmr.2015.4042openalex-snapshot
1-O-acetylbritannilactone combined with gemcitabine elicits growth inhibition and apoptosis in A549 human non-small cell lung cancer cells
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Eupatolide inhibits the TGF‑β1‑induced migration of breast cancer cells via downregulation of SMAD3 phosphorylation and transcriptional repression of ALK5
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Britanin Suppresses IgE/Ag-Induced Mast Cell Activation by Inhibiting the Syk Pathway
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