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Human Bub1 protects centromeric sister-chromatid cohesion through Shugoshin during mitosis

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/1097-0320(20010201)43:2<101::aid-cyto1024>3.0.co;2-8openalex-snapshot
Improvements in cytogenetic slide preparation: Controlled chromosome spreading, chemical aging and gradual denaturing
inferredcites →https://doi.org/10.1007/bf00291909openalex-snapshot
Mechanisms of chromosome orientation revealed by two meiotic mutants in Drosophila melanogaster
inferredcites →https://doi.org/10.1007/s004120050392openalex-snapshot
The mitotic centromeric protein MEI-S332 and its role in sister-chromatid cohesion
inferredcites →https://doi.org/10.1016/0092-8674(95)90166-3openalex-snapshot
Mei-S332, a drosophila protein required for sister-chromatid cohesion, can localize to meiotic centromere regions
inferredcites →https://doi.org/10.1016/j.cell.2004.08.016openalex-snapshot
Vertebrate Shugoshin Links Sister Centromere Cohesion and Kinetochore Microtubule Stability in Mitosis
inferredcites →https://doi.org/10.1016/j.cub.2004.01.051openalex-snapshot
Two Fission Yeast Homologs of Drosophila Mei-S332 Are Required for Chromosome Segregation during Meiosis I and II
inferredcites →https://doi.org/10.1016/j.cub.2004.03.001openalex-snapshot
Maintenance of Cohesin at Centromeres after Meiosis I in Budding Yeast Requires a Kinetochore-Associated Protein Related to MEI-S332
inferredcites →https://doi.org/10.1016/j.cub.2004.07.011openalex-snapshot
Taste Perception: Drosophila – A Model of Good Taste
inferredcites →https://doi.org/10.1016/j.devcel.2004.06.006openalex-snapshot
Timing and Checkpoints in the Regulation of Mitotic Progression
inferredcites →https://doi.org/10.1016/j.molcel.2004.09.031openalex-snapshot
Phosphorylation of Cdc20 by Bub1 Provides a Catalytic Mechanism for APC/C Inhibition by the Spindle Checkpoint
inferredcites →https://doi.org/10.1016/s0092-8674(00)00130-6openalex-snapshot
Cleavage of Cohesin by the CD Clan Protease Separin Triggers Anaphase in Yeast
inferredcites →https://doi.org/10.1016/s0092-8674(00)00132-xopenalex-snapshot
Two Distinct Pathways Remove Mammalian Cohesin from Chromosome Arms in Prophase and from Centromeres in Anaphase
inferredcites →https://doi.org/10.1016/s0092-8674(03)00083-7openalex-snapshot
Un Ménage à Quatre
inferredcites →https://doi.org/10.1016/s0092-8674(03)00115-6openalex-snapshot
Centromeres and Kinetochores
inferredcites →https://doi.org/10.1016/s0955-0674(00)00092-2openalex-snapshot
Sister chromatid cohesion: the beginning of a long and beautiful relationship
inferredcites →https://doi.org/10.1016/s0955-0674(02)00328-9openalex-snapshot
Bi-orienting chromosomes on the mitotic spindle
inferredcites →https://doi.org/10.1016/s0955-0674(02)00382-4openalex-snapshot
Regulation of APC–Cdc20 by the spindle checkpoint
inferredcites →https://doi.org/10.1016/s1097-2765(00)80126-4openalex-snapshot
Direct Binding of CDC20 Protein Family Members Activates the Anaphase-Promoting Complex in Mitosis and G1
inferredcites →https://doi.org/10.1016/s1097-2765(02)00473-2openalex-snapshot
The Dissociation of Cohesin from Chromosomes in Prophase Is Regulated by Polo-like Kinase
inferredcites →https://doi.org/10.1016/s1097-2765(02)00540-3openalex-snapshot
The Anaphase-Promoting Complex
inferredcites →https://doi.org/10.1016/s1534-5807(01)00019-3openalex-snapshot
Mad2-Independent Inhibition of APCCdc20 by the Mitotic Checkpoint Protein BubR1
inferredcites →https://doi.org/10.1038/35074598openalex-snapshot
Fission yeast Bub1 is essential in setting up the meiotic pattern of chromosome segregation
inferredcites →https://doi.org/10.1038/35078107openalex-snapshot
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
inferredcites →https://doi.org/10.1038/nature02312openalex-snapshot
The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis
inferredcites →https://doi.org/10.1038/nrm929openalex-snapshot
The spindle checkpoint: structural insights into dynamic signalling
inferredcites →https://doi.org/10.1038/nsmb748openalex-snapshot
The Mad2 spindle checkpoint protein has two distinct natively folded states
inferredcites →https://doi.org/10.1038/sj.onc.1207374openalex-snapshot
The spindle checkpoint, aneuploidy, and cancer
inferredcites →https://doi.org/10.1083/jcb.153.1.137openalex-snapshot
Anaphase-Promoting Complex/Cyclosome–Dependent Proteolysis of Human Cyclin a Starts at the Beginning of Mitosis and Is Not Subject to the Spindle Assembly Checkpoint
inferredcites →https://doi.org/10.1093/genetics/130.4.827openalex-snapshot
The Drosophila mei-S332 gene promotes sister-chromatid cohesion in meiosis following kinetochore differentiation.
inferredcites →https://doi.org/10.1101/gad.1013102openalex-snapshot
The anaphase-promoting complex: it's not just for mitosis any more
inferredcites →https://doi.org/10.1101/gad.12.13.1986openalex-snapshot
Identification of Xenopus SMC protein complexes required for sister chromatid cohesion
inferredcites →https://doi.org/10.1101/gad.12.24.3843openalex-snapshot
Maintenance of sister-chromatid cohesion at the centromere by the Drosophila MEI-S332 protein
inferredcites →https://doi.org/10.1101/gad.249202openalex-snapshot
Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis
inferredcites →https://doi.org/10.1101/gad.955102openalex-snapshot
The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion, and repair
inferredcites →https://doi.org/10.1126/science.1061376openalex-snapshot
Cohesin Cleavage by Separase Required for Anaphase and Cytokinesis in Human Cells
inferredcites →https://doi.org/10.1126/science.1074757openalex-snapshot
Segregating Sister Genomes: The Molecular Biology of Chromosome Separation
inferredcites →https://doi.org/10.1126/science.1094220openalex-snapshot
A Genome-Wide Screen Identifies Genes Required for Centromeric Cohesion
inferredcites →https://doi.org/10.1126/science.285.5426.418openalex-snapshot
Identification of a Vertebrate Sister-Chromatid Separation Inhibitor Involved in Transformation and Tumorigenesis
inferredcites →https://doi.org/10.1242/jcs.01352openalex-snapshot
Modifying sister chromatid cohesion for meiosis

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3193407openalex-extracted
The RZZ Complex Facilitates Mad1 Binding to Bub1 Ensuring Efficient Checkpoint Signaling
inferred← citeshttps://doi.org/10.1002/9780470015902.a0022413.pub2openalex-snapshot
Sister Chromatid Cohesion, Chromosome Instability ( CIN ) and Diseases
inferred← citeshttps://doi.org/10.1002/bies.202000018openalex-snapshot
Meiosis I Kinase Regulators: Conserved Orchestrators of Reductional Chromosome Segregation
inferred← citeshttps://doi.org/10.1002/bies.20240openalex-snapshot
Shugoshin: a centromeric guardian senses tension
inferred← citeshttps://doi.org/10.1002/bies.20448openalex-snapshot
Shugoshin and PP2A, shared duties at the centromere
inferred← citeshttps://doi.org/10.1002/cbin.70220openalex-snapshot
Sister Chromatid Cohesion: A Multilayered Regulatory Network Beyond the Cohesin Ring
inferred← citeshttps://doi.org/10.1002/hep.21330openalex-snapshot
Comparison of gene expression profiles between Opisthorchis viverrini and non‐Opisthorchis viverrini associated human intrahepatic cholangiocarcinoma†
inferred← citeshttps://doi.org/10.1007/7050_2007_027openalex-snapshot
Sister Chromatid Cohesion and Centromere Organization in Meiosis
inferred← citeshttps://doi.org/10.1007/978-0-387-69076-6_10openalex-snapshot
Post-Translational Modifications that Regulate Kinetochore Activity
inferred← citeshttps://doi.org/10.1007/978-0-387-69076-6_13openalex-snapshot
Roles of Centromeres and Kinetochores in Meiosis
inferred← citeshttps://doi.org/10.1007/978-1-4614-0016-5_14openalex-snapshot
Polyomaviruses and Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4939-3542-0_10openalex-snapshot
Measuring Kinetochore–Microtubule Attachment Stability in Cultured Cells
inferred← citeshttps://doi.org/10.1007/978-3-540-73855-8_2openalex-snapshot
Getting In and Out of Mitosis
inferred← citeshttps://doi.org/10.1007/s00412-005-0010-zopenalex-snapshot
Kiss and break up—a safe passage to anaphase in mitosis and meiosis
inferred← citeshttps://doi.org/10.1007/s00412-005-0331-yopenalex-snapshot
Rephrasing anaphase: separase FEARs shugoshin
inferred← citeshttps://doi.org/10.1007/s00412-007-0125-5openalex-snapshot
Functional links between Drosophila Nipped-B and cohesin in somatic and meiotic cells
inferred← citeshttps://doi.org/10.1007/s00412-007-0139-zopenalex-snapshot
The Suv39h–HP1 histone methylation pathway is dispensable for enrichment and protection of cohesin at centromeres in mammalian cells
inferred← citeshttps://doi.org/10.1007/s00412-007-0141-5openalex-snapshot
Arabidopsis sister chromatids often show complete alignment or separation along a 1.2-Mb euchromatic region but no cohesion “hot spots”
inferred← citeshttps://doi.org/10.1007/s00412-008-0190-4openalex-snapshot
Shugoshin regulates cohesion by driving relocalization of PP2A in Xenopus extracts
inferred← citeshttps://doi.org/10.1007/s00412-009-0250-4openalex-snapshot
Haspin: a newly discovered regulator of mitotic chromosome behavior
inferred← citeshttps://doi.org/10.1007/s00412-013-0437-6openalex-snapshot
Cell division: control of the chromosomal passenger complex in time and space
inferred← citeshttps://doi.org/10.1007/s00412-016-0592-7openalex-snapshot
Bub1 targeting to centromeres is sufficient for Sgo1 recruitment in the absence of kinetochores
inferred← citeshttps://doi.org/10.1007/s00438-007-0242-0openalex-snapshot
Random homologous pairing and incomplete sister chromatid alignment are common in angiosperm interphase nuclei
inferred← citeshttps://doi.org/10.1007/s10577-008-9013-yopenalex-snapshot
Studies of meiosis disclose distinct roles of cohesion in the core centromere and pericentromeric regions
inferred← citeshttps://doi.org/10.1007/s10577-012-9289-9openalex-snapshot
Establishment of the vertebrate kinetochores
inferred← citeshttps://doi.org/10.1007/s11427-015-4956-7openalex-snapshot
Regulation of sister chromatid cohesion during the mitotic cell cycle
inferred← citeshttps://doi.org/10.1007/s11427-023-2604-8openalex-snapshot
TIP60 acetylation of Bub1 regulates centromeric H2AT120 phosphorylation for faithful chromosome segregation
inferred← citeshttps://doi.org/10.1007/s13277-011-0284-0openalex-snapshot
Lentivirus-mediated siRNA interference targeting SGO-1 inhibits human NSCLC cell growth
inferred← citeshttps://doi.org/10.1007/s13277-013-0758-3openalex-snapshot
Shugoshin1 enhances multidrug resistance of gastric cancer cells by regulating MRP1, Bcl-2, and Bax genes
inferred← citeshttps://doi.org/10.1016/j.aqrep.2024.102039openalex-snapshot
Transcriptome analysis of the bipotential gonads of hermaphroditic bivalve species Tridacna crocea unravels the potential genes responsible for spermatogenesis
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2012.05.027openalex-snapshot
Cohesin: A guardian of genome integrity
inferred← citeshttps://doi.org/10.1016/j.bbcan.2008.04.001openalex-snapshot
Preventing aneuploidy: The contribution of mitotic checkpoint proteins
inferred← citeshttps://doi.org/10.1016/j.bbcan.2008.04.003openalex-snapshot
The regulation of sister chromatid cohesion
inferred← citeshttps://doi.org/10.1016/j.bpj.2015.10.024openalex-snapshot
Erroneous Silencing of the Mitotic Checkpoint by Aberrant Spindle Pole-Kinetochore Coordination
inferred← citeshttps://doi.org/10.1016/j.ceb.2005.10.003openalex-snapshot
Shugoshin: guardian spirit at the centromere
inferred← citeshttps://doi.org/10.1016/j.cell.2006.09.040openalex-snapshot
Wapl Controls the Dynamic Association of Cohesin with Chromatin
inferred← citeshttps://doi.org/10.1016/j.cell.2007.11.046openalex-snapshot
Mps1 Phosphorylates Borealin to Control Aurora B Activity and Chromosome Alignment
inferred← citeshttps://doi.org/10.1016/j.celrep.2015.08.045openalex-snapshot
An Alternatively Spliced Bifunctional Localization Signal Reprograms Human Shugoshin 1 to Protect Centrosomal Instead of Centromeric Cohesin
inferred← citeshttps://doi.org/10.1016/j.celrep.2021.109740openalex-snapshot
Bub1 and CENP-U redundantly recruit Plk1 to stabilize kinetochore-microtubule attachments and ensure accurate chromosome segregation
inferred← citeshttps://doi.org/10.1016/j.cub.2006.03.049openalex-snapshot
Human Scc4 Is Required for Cohesin Binding to Chromatin, Sister-Chromatid Cohesion, and Mitotic Progression
inferred← citeshttps://doi.org/10.1016/j.cub.2006.10.061openalex-snapshot
Human Wapl Is a Cohesin-Binding Protein that Promotes Sister-Chromatid Resolution in Mitotic Prophase
inferred← citeshttps://doi.org/10.1016/j.cub.2007.02.029openalex-snapshot
Sororin Is Required for Stable Binding of Cohesin to Chromatin and for Sister Chromatid Cohesion in Interphase
inferred← citeshttps://doi.org/10.1016/j.cub.2007.07.009openalex-snapshot
PHB2 Protects Sister-Chromatid Cohesion in Mitosis
inferred← citeshttps://doi.org/10.1016/j.cub.2009.07.017openalex-snapshot
Ska3 Is Required for Spindle Checkpoint Silencing and the Maintenance of Chromosome Cohesion in Mitosis
inferred← citeshttps://doi.org/10.1016/j.cub.2013.02.028openalex-snapshot
Chromosome Segregation: Disarming the Protector
inferred← citeshttps://doi.org/10.1016/j.cub.2013.07.078openalex-snapshot
Phospho-H2A and Cohesin Specify Distinct Tension-Regulated Sgo1 Pools at Kinetochores and Inner Centromeres
inferred← citeshttps://doi.org/10.1016/j.cub.2023.11.061openalex-snapshot
Age-dependent loss of cohesion protection in human oocytes
inferred← citeshttps://doi.org/10.1016/j.devcel.2006.03.010openalex-snapshot
PP2A Is Required for Centromeric Localization of Sgo1 and Proper Chromosome Segregation
inferred← citeshttps://doi.org/10.1016/j.devcel.2006.09.018openalex-snapshot
Regulation of Mitotic Chromosome Cohesion by Haspin and Aurora B
inferred← citeshttps://doi.org/10.1016/j.devcel.2007.08.008openalex-snapshot
Bub1 Maintains Centromeric Cohesion by Activation of the Spindle Checkpoint
inferred← citeshttps://doi.org/10.1016/j.devcel.2007.12.007openalex-snapshot
sSgo1, a Major Splice Variant of Sgo1, Functions in Centriole Cohesion Where It Is Regulated by Plk1
inferred← citeshttps://doi.org/10.1016/j.exer.2019.04.005openalex-snapshot
Comparative transcriptome analysis of human conjunctiva between normal and conjunctivochalasis persons by RNA sequencing
inferred← citeshttps://doi.org/10.1016/j.febslet.2006.03.081openalex-snapshot
The spindle assembly checkpoint: Preventing chromosome mis‐segregation during mitosis and meiosis
inferred← citeshttps://doi.org/10.1016/j.febslet.2008.10.023openalex-snapshot
Nucleophosmin is required for chromosome congression, proper mitotic spindle formation, and kinetochore‐microtubule attachment in HeLa cells
inferred← citeshttps://doi.org/10.1016/j.leukres.2012.10.002openalex-snapshot
A novel treatment strategy targeting shugoshin 1 in hematological malignancies
inferred← citeshttps://doi.org/10.1016/j.molcel.2015.06.018openalex-snapshot
Mitotic Transcription Installs Sgo1 at Centromeres to Coordinate Chromosome Segregation
inferred← citeshttps://doi.org/10.1016/j.molcel.2018.03.032openalex-snapshot
The BUB3-BUB1 Complex Promotes Telomere DNA Replication
inferred← citeshttps://doi.org/10.1016/j.molcel.2026.07.023openalex-snapshot
α-Satellite RNA maintains centromeric cohesion through R-loops
inferred← citeshttps://doi.org/10.1016/j.mrgentox.2007.10.015openalex-snapshot
Spindle formation, chromosome segregation and the spindle checkpoint in mammalian oocytes and susceptibility to meiotic error
inferred← citeshttps://doi.org/10.1016/j.neo.2020.02.001openalex-snapshot
TGFBR2 mediated phosphorylation of BUB1 at Ser-318 is required for transforming growth factor-β signaling
inferred← citeshttps://doi.org/10.1016/j.semcdb.2011.03.008openalex-snapshot
Mutual regulation between the spindle checkpoint and APC/C
inferred← citeshttps://doi.org/10.1016/j.semcdb.2011.03.013openalex-snapshot
The sister bonding of duplicated chromosomes
inferred← citeshttps://doi.org/10.1016/j.str.2014.08.020openalex-snapshot
Substrate-Specific Activation of the Mitotic Kinase Bub1 through Intramolecular Autophosphorylation and Kinetochore Targeting
inferred← citeshttps://doi.org/10.1016/j.tcb.2005.07.005openalex-snapshot
The spindle checkpoint: tension versus attachment
inferred← citeshttps://doi.org/10.1016/j.tcb.2005.11.006openalex-snapshot
Mitosis: a matter of getting rid of the right protein at the right time
inferred← citeshttps://doi.org/10.1016/j.tig.2005.05.009openalex-snapshot
Sister chromatid cohesion along arms and at centromeres
inferred← citeshttps://doi.org/10.1016/j.tig.2012.03.003openalex-snapshot
Shugoshins: from protectors of cohesion to versatile adaptors at the centromere
inferred← citeshttps://doi.org/10.1016/j.wneu.2020.02.159openalex-snapshot
Bioinformatical Analysis of Gene Expression Omnibus Database Associates TAF7/CCNB1, TAF7/CCNA2, and GTF2E2/CDC20 Pathways with Glioblastoma Development and Prognosis
inferred← citeshttps://doi.org/10.1016/j.yexcr.2005.07.018openalex-snapshot
Shugoshin, a guardian for sister chromatid segregation
inferred← citeshttps://doi.org/10.1016/s0929-6646(10)60002-2openalex-snapshot
Suppression of Genomic Instabilities Caused by Chromosome Mis-segregation: A Perspective From Studying BubR1 and Sgo1
inferred← citeshttps://doi.org/10.1038/cr.2007.55openalex-snapshot
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
inferred← citeshttps://doi.org/10.1038/emboj.2011.187openalex-snapshot
Shugoshin is a Mad1/Cdc20‐like interactor of Mad2
inferred← citeshttps://doi.org/10.1038/emboj.2011.226openalex-snapshot
PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution
inferred← citeshttps://doi.org/10.1038/emboj.2013.16openalex-snapshot
Structural insights into the regulation of cohesion establishment by Wpl1
inferred← citeshttps://doi.org/10.1038/nature04663openalex-snapshot
Shugoshin collaborates with protein phosphatase 2A to protect cohesin
inferred← citeshttps://doi.org/10.1038/nature09390openalex-snapshot
Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation
inferred← citeshttps://doi.org/10.1038/ncb2280openalex-snapshot
Cleavage of cohesin rings coordinates the separation of centrioles and chromatids
inferred← citeshttps://doi.org/10.1038/ncb2637openalex-snapshot
Phosphorylation-enabled binding of SGO1–PP2A to cohesin protects sororin and centromeric cohesion during mitosis
inferred← citeshttps://doi.org/10.1038/ncomms3677openalex-snapshot
Bod1 regulates protein phosphatase 2A at mitotic kinetochores
inferred← citeshttps://doi.org/10.1038/ncomms4445openalex-snapshot
Dynamic phosphorylation of HP1α regulates mitotic progression in human cells
inferred← citeshttps://doi.org/10.1038/ncomms7775openalex-snapshot
Borealin dimerization mediates optimal CPC checkpoint function by enhancing localization to centromeres and kinetochores
inferred← citeshttps://doi.org/10.1038/ncomms9364openalex-snapshot
Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation
inferred← citeshttps://doi.org/10.1038/nrm2163openalex-snapshot
The spindle-assembly checkpoint in space and time
inferred← citeshttps://doi.org/10.1038/nrm3349openalex-snapshot
Geometry and force behind kinetochore orientation: lessons from meiosis
inferred← citeshttps://doi.org/10.1038/onc.2011.152openalex-snapshot
A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion
inferred← citeshttps://doi.org/10.1038/s41366-021-01002-1openalex-snapshot
Key signaling networks are dysregulated in patients with the adipose tissue disorder, lipedema
inferred← citeshttps://doi.org/10.1038/s41467-017-00774-3openalex-snapshot
Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I
inferred← citeshttps://doi.org/10.1038/s41467-019-12255-wopenalex-snapshot
Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection
inferred← citeshttps://doi.org/10.1038/s41467-025-62316-6openalex-snapshot
CENcyclopedia: dynamic landscape of kinetochore architecture throughout the cell cycle
inferred← citeshttps://doi.org/10.1038/s41580-023-00609-8openalex-snapshot
Genome control by SMC complexes
inferred← citeshttps://doi.org/10.1038/s41580-025-00933-1openalex-snapshot
Organization of replicated chromosomes by DNA loops and sister chromatid cohesion
inferred← citeshttps://doi.org/10.1038/s41586-020-2187-yopenalex-snapshot
Separase-triggered apoptosis enforces minimal length of mitosis
inferred← citeshttps://doi.org/10.1038/s41594-023-00968-yopenalex-snapshot
Structural basis of centromeric cohesion protection
inferred← citeshttps://doi.org/10.1038/s41598-019-39479-6openalex-snapshot
Bub1 kinase- and H2A phosphorylation-independent regulation of Shugoshin proteins under glucose-restricted conditions
inferred← citeshttps://doi.org/10.1038/s41598-019-46064-4openalex-snapshot
The Homeobox gene, HOXB13, Regulates a Mitotic Protein-Kinase Interaction Network in Metastatic Prostate Cancers
inferred← citeshttps://doi.org/10.1038/s44318-024-00104-6openalex-snapshot
A non-canonical role of the inner kinetochore in regulating sister-chromatid cohesion at centromeres
inferred← citeshttps://doi.org/10.1038/s44318-024-00228-9openalex-snapshot
Requirement of Nek2a and cyclin A2 for Wapl-dependent removal of cohesin from prophase chromatin
inferred← citeshttps://doi.org/10.1038/s44318-025-00465-6openalex-snapshot
A chromatin-remodeling-independent role for ATRX in protecting centromeric cohesion
inferred← citeshttps://doi.org/10.1038/sj.emboj.7600641openalex-snapshot
A dual role for Bub1 in the spindle checkpoint and chromosome congression
inferred← citeshttps://doi.org/10.1042/bst0370971openalex-snapshot
Dividing the goods: co-ordination of chromosome biorientation and mitotic checkpoint signalling by mitotic kinases
inferred← citeshttps://doi.org/10.1042/ebc20190077openalex-snapshot
Functioning mechanisms of Shugoshin-1 in centromeric cohesion during mitosis
inferred← citeshttps://doi.org/10.1073/pnas.0703164104openalex-snapshot
Surveillance mechanism linking Bub1 loss to the p53 pathway
inferred← citeshttps://doi.org/10.1073/pnas.0708582104openalex-snapshot
PP2A as a mercenary for warring kinases in the egg
inferred← citeshttps://doi.org/10.1073/pnas.0903075106openalex-snapshot
Heterozygosity for a Bub1 mutation causes female-specific germ cell aneuploidy in mice
inferred← citeshttps://doi.org/10.1073/pnas.2405177121openalex-snapshot
Molecular mechanism and functional significance of Wapl interaction with the Cohesin complex
inferred← citeshttps://doi.org/10.1074/jbc.m113.510388openalex-snapshot
Phosphorylation of Myosin II-interacting Guanine Nucleotide Exchange Factor (MyoGEF) at Threonine 544 by Aurora B Kinase Promotes the Binding of Polo-like Kinase 1 to MyoGEF
inferred← citeshttps://doi.org/10.1074/jbc.m611279200openalex-snapshot
The DYNLT3 Light Chain Directly Links Cytoplasmic Dynein to a Spindle Checkpoint Protein, Bub3
inferred← citeshttps://doi.org/10.1074/jbc.m807083200openalex-snapshot
Multiple Anaphase-promoting Complex/Cyclosome Degrons Mediate the Degradation of Human Sgo1
inferred← citeshttps://doi.org/10.1074/jbc.r900005200openalex-snapshot
Kinase Signaling in the Spindle Checkpoint
inferred← citeshttps://doi.org/10.1074/jbc.ra118.005978openalex-snapshot
Aurora B kinase activity–dependent and –independent functions of the chromosomal passenger complex in regulating sister chromatid cohesion
inferred← citeshttps://doi.org/10.1074/jbc.ra118.006046openalex-snapshot
A positive feedback mechanism ensures proper assembly of the functional inner centromere during mitosis in human cells
inferred← citeshttps://doi.org/10.1083/jcb.200502163openalex-snapshot
Plx1 is the 3F3/2 kinase responsible for targeting spindle checkpoint proteins to kinetochores
inferred← citeshttps://doi.org/10.1083/jcb.200606020openalex-snapshot
Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells
inferred← citeshttps://doi.org/10.1083/jcb.200609044openalex-snapshot
Bub1 is essential for assembly of the functional inner centromere
inferred← citeshttps://doi.org/10.1083/jcb.200701043openalex-snapshot
The acetyltransferase activity of San stabilizes the mitotic cohesin at the centromeres in a shugoshin-independent manner
inferred← citeshttps://doi.org/10.1083/jcb.200701122openalex-snapshot
Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments
inferred← citeshttps://doi.org/10.1083/jcb.200703133openalex-snapshot
PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores
inferred← citeshttps://doi.org/10.1083/jcb.200706015openalex-snapshot
Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis
inferred← citeshttps://doi.org/10.1083/jcb.200902128openalex-snapshot
Bub1 regulates chromosome segregation in a kinetochore-independent manner
inferred← citeshttps://doi.org/10.1083/jcb.200909005openalex-snapshot
Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases
inferred← citeshttps://doi.org/10.1083/jcb.201012035openalex-snapshot
Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation
inferred← citeshttps://doi.org/10.1083/jcb.201110013openalex-snapshot
Structural analysis reveals features of the spindle checkpoint kinase Bub1–kinetochore subunit Knl1 interaction
inferred← citeshttps://doi.org/10.1083/jcb.201205115openalex-snapshot
Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression
inferred← citeshttps://doi.org/10.1083/jcb.201907087openalex-snapshot
Untangling the contribution of Haspin and Bub1 to Aurora B function during mitosis
inferred← citeshttps://doi.org/10.1083/jcb.202108156openalex-snapshot
Mechanistic basis for Sgo1-mediated centromere localization and function of the CPC
inferred← citeshttps://doi.org/10.1091/mbc.e05-03-0190openalex-snapshot
Securin and Separase Phosphorylation Act Redundantly to Maintain Sister Chromatid Cohesion in Mammalian Cells
inferred← citeshttps://doi.org/10.1091/mbc.e05-08-0802openalex-snapshot
The V260I Mutation in Fission Yeast α-Tubulin Atb2 Affects Microtubule Dynamics and EB1-Mal3 Localization and Activates the Bub1 Branch of the Spindle Checkpoint
inferred← citeshttps://doi.org/10.1091/mbc.e06-03-0240openalex-snapshot
Phosphorylation- and Polo-Box–dependent Binding of Plk1 to Bub1 Is Required for the Kinetochore Localization of Plk1
inferred← citeshttps://doi.org/10.1091/mbc.e07-06-0556openalex-snapshot
CENP-O Class Proteins Form a Stable Complex and Are Required for Proper Kinetochore Function
inferred← citeshttps://doi.org/10.1091/mbc.e07-07-0633openalex-snapshot
The Human Spindle Assembly Checkpoint Protein Bub3 Is Required for the Establishment of Efficient Kinetochore–Microtubule Attachments
inferred← citeshttps://doi.org/10.1091/mbc.e08-10-1047openalex-snapshot
Systematic Analysis in Caenorhabditis elegans Reveals that the Spindle Checkpoint Is Composed of Two Largely Independent Branches
inferred← citeshttps://doi.org/10.1091/mbc.e11-01-0009openalex-snapshot
Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells
inferred← citeshttps://doi.org/10.1091/mbc.e20-12-0778openalex-snapshot
SET levels contribute to cohesion fatigue
inferred← citeshttps://doi.org/10.1091/mbc.e23-08-0303openalex-snapshot
CDK11 facilitates centromeric transcription to maintain centromeric cohesion during mitosis
inferred← citeshttps://doi.org/10.1093/jmcb/mjad061openalex-snapshot
Sgo1 interacts with CENP-A to guide accurate chromosome segregation in mitosis
inferred← citeshttps://doi.org/10.1093/molehr/gaq065openalex-snapshot
Reduced expression of Mad2 and Bub1 proteins is associated with spontaneous miscarriages
inferred← citeshttps://doi.org/10.1093/nar/gku696openalex-snapshot
The CHR site: definition and genome-wide identification of a cell cycle transcriptional element
inferred← citeshttps://doi.org/10.1097/01.aids.0000180788.92627.e7openalex-snapshot
Premature sister chromatid separation in HIV-1-infected peripheral blood lymphocytes
inferred← citeshttps://doi.org/10.1101/2021.02.01.429225openalex-snapshot
Molecular mechanism underlying the non-essentiality of Bub1 for the fidelity of chromosome segregation in human cells
inferred← citeshttps://doi.org/10.1101/2022.02.01.478617openalex-snapshot
CDK11 Promotes Centromeric Transcription to Maintain Centromeric Cohesion during Mitosis
inferred← citeshttps://doi.org/10.1101/2024.06.27.600994openalex-snapshot
Molecular evolution of the mammalian kinetochore complex
inferred← citeshttps://doi.org/10.1101/gad.1320505openalex-snapshot
Dynamic molecular linkers of the genome: the first decade of SMC proteins
inferred← citeshttps://doi.org/10.1101/gad.1373005openalex-snapshot
The core centromere and Sgo1 establish a 50-kb cohesin-protected domain around centromeres during meiosis I
inferred← citeshttps://doi.org/10.1101/gad.1724308openalex-snapshot
The cohesin complex and its roles in chromosome biology
inferred← citeshttps://doi.org/10.1101/gad.1819409openalex-snapshot
The Scc2/Scc4 cohesin loader determines the distribution of cohesin on budding yeast chromosomes
inferred← citeshttps://doi.org/10.1101/gad.210377.112openalex-snapshot
Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin
inferred← citeshttps://doi.org/10.1111/j.1365-2443.2007.01093.xopenalex-snapshot
Sister chromatid cohesion: the cohesin cleavage model does not ring true
inferred← citeshttps://doi.org/10.1111/j.1365-313x.2012.04979.xopenalex-snapshot
The Arabidopsis SYN3 cohesin protein is important for early meiotic events
inferred← citeshttps://doi.org/10.1111/nph.14415openalex-snapshot
Dynamic location changes of Bub1‐phosphorylated‐H2AThr133 with CENH3 nucleosome in maize centromeric regions
inferred← citeshttps://doi.org/10.1126/sciadv.abk0114openalex-snapshot
Biallelic BUB1 mutations cause microcephaly, developmental delay, and variable effects on cohesion and chromosome segregation
inferred← citeshttps://doi.org/10.1126/science.1180189openalex-snapshot
Phosphorylation of H2A by Bub1 Prevents Chromosomal Instability Through Localizing Shugoshin
inferred← citeshttps://doi.org/10.1126/science.1184770openalex-snapshot
Directing the Centromere Guardian
inferred← citeshttps://doi.org/10.1126/sciimmunol.adq2055openalex-snapshot
A noncanonical cytoplasmic role for BUB1 in restraining DNA damage–induced dsRNA accumulation and sensing within stress granules
inferred← citeshttps://doi.org/10.1128/jvi.00713-10openalex-snapshot
Bub1 and CENP-F Can Contribute to Kaposi's Sarcoma-Associated Herpesvirus Genome Persistence by Targeting LANA to Kinetochores
inferred← citeshttps://doi.org/10.1128/jvi.02224-13openalex-snapshot
Replication Stress and Mitotic Dysfunction in Cells Expressing Simian Virus 40 Large T Antigen
inferred← citeshttps://doi.org/10.1128/mcb.00161-14openalex-snapshot
TRF1 Ensures the Centromeric Function of Aurora-B and Proper Chromosome Segregation
inferred← citeshttps://doi.org/10.1128/mcb.00980-09openalex-snapshot
Histone H3 Exerts a Key Function in Mitotic Checkpoint Control
inferred← citeshttps://doi.org/10.1128/mcb.01176-14openalex-snapshot
Shugoshins: Tension-Sensitive Pericentromeric Adaptors Safeguarding Chromosome Segregation
inferred← citeshttps://doi.org/10.1128/mcb.05326-11openalex-snapshot
Bub1 and BubR1: at the Interface between Chromosome Attachment and the Spindle Checkpoint
inferred← citeshttps://doi.org/10.1146/annurev.cellbio.24.110707.175350openalex-snapshot
Sister Chromatid Cohesion: A Simple Concept with a Complex Reality
inferred← citeshttps://doi.org/10.1155/2012/195903openalex-snapshot
Mitotic Kinases and p53 Signaling
inferred← citeshttps://doi.org/10.1158/0008-5472.can-07-6330openalex-snapshot
Impaired Bub1 Function In vivo Compromises Tension-Dependent Checkpoint Function Leading to Aneuploidy and Tumorigenesis
inferred← citeshttps://doi.org/10.1158/0008-5472.can-10-0015openalex-snapshot
A Chemosensitization Screen Identifies TP53RK, a Kinase that Restrains Apoptosis after Mitotic Stress
inferred← citeshttps://doi.org/10.1159/000218126openalex-snapshot
SMC Proteins and Their Multiple Functions in Higher Plants
inferred← citeshttps://doi.org/10.1159/000323793openalex-snapshot
The Role of Shugoshin in Meiotic Chromosome Segregation
inferred← citeshttps://doi.org/10.1177/1535370219881360openalex-snapshot
Role of E2Fs and mitotic regulators controlled by E2Fs in the epithelial to mesenchymal transition
inferred← citeshttps://doi.org/10.1177/1535370221991094openalex-snapshot
Mitotic kinases as drivers of the epithelial-to-mesenchymal transition and as therapeutic targets against breast cancers
inferred← citeshttps://doi.org/10.1177/1947601909358184openalex-snapshot
Germinal Cell Aplasia in Kif18a Mutant Male Mice Due to Impaired Chromosome Congression and Dysregulated BubR1 and CENP-E
inferred← citeshttps://doi.org/10.1186/1747-1028-1-9openalex-snapshot
The Yin and Yang of centromeric cohesion of sister chromatids: mitotic kinases meet protein phosphatase 2A.
inferred← citeshttps://doi.org/10.1186/1747-1028-3-10openalex-snapshot
The chromosomal passenger complex and the spindle assembly checkpoint: kinetochore-microtubule error correction and beyond
inferred← citeshttps://doi.org/10.1186/1747-1028-9-3openalex-snapshot
Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells
inferred← citeshttps://doi.org/10.1186/1756-8935-8-3openalex-snapshot
Constitutive heterochromatin formation and transcription in mammals
inferred← citeshttps://doi.org/10.1186/s13008-023-00088-5openalex-snapshot
Sustained Shugoshin 1 downregulation reduces tumor growth and metastasis in a mouse xenograft tumor model of triple-negative breast cancer
inferred← citeshttps://doi.org/10.1186/s13045-016-0238-5openalex-snapshot
Haplo-insufficiency of both BubR1 and SGO1 accelerates cellular senescence
inferred← citeshttps://doi.org/10.1186/s13046-021-02179-zopenalex-snapshot
BUB1 drives the occurrence and development of bladder cancer by mediating the STAT3 signaling pathway
inferred← citeshttps://doi.org/10.1186/s13046-024-03086-9openalex-snapshot
BUB1 regulates non-homologous end joining pathway to mediate radioresistance in triple-negative breast cancer
inferred← citeshttps://doi.org/10.1186/s43042-025-00809-1openalex-snapshot
Budding Uninhibited by Benzimidazole 1 in pancreatic cancer: theoretical, mechanistic and bioinformatic insights
inferred← citeshttps://doi.org/10.1242/jcs.007963openalex-snapshot
CDK11p58 is required for the maintenance of sister chromatid cohesion
inferred← citeshttps://doi.org/10.1242/jcs.011528openalex-snapshot
The complete removal of cohesin from chromosome arms depends on separase
inferred← citeshttps://doi.org/10.1242/jcs.02487openalex-snapshot
Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20
inferred← citeshttps://doi.org/10.1242/jcs.02614openalex-snapshot
Silencing Cenp-F weakens centromeric cohesion, prevents chromosome alignment and activates the spindle checkpoint
inferred← citeshttps://doi.org/10.1242/jcs.027862openalex-snapshot
Arabidopsis SMG7 protein is required for exit from meiosis
inferred← citeshttps://doi.org/10.1242/jcs.03425openalex-snapshot
Aurora B controls the association of condensin I but not condensin II with mitotic chromosomes
inferred← citeshttps://doi.org/10.1242/jcs.059501openalex-snapshot
Sgo1 establishes the centromeric cohesion protection mechanism in G2 before subsequent Bub1-dependent recruitment in mitosis
inferred← citeshttps://doi.org/10.1242/jcs.063347openalex-snapshot
The nuclear scaffold protein SAF-A is required for kinetochore–microtubule attachment and contributes to the targeting of Aurora-A to mitotic spindles
inferred← citeshttps://doi.org/10.1242/jcs.087106openalex-snapshot
Protein phosphatases and the regulation of mitosis
inferred← citeshttps://doi.org/10.1242/jcs.161273openalex-snapshot
Sgo1 recruits PP2A to chromosomes to ensure sister chromatid bi-orientation in mitosis
inferred← citeshttps://doi.org/10.1371/journal.pgen.0030213openalex-snapshot
Bub1 Kinase Targets Sgo1 to Ensure Efficient Chromosome Biorientation in Budding Yeast Mitosis
inferred← citeshttps://doi.org/10.1371/journal.pgen.0030213.eoropenalex-snapshot
Bub1 Kinase Targets Sgo1 to Ensure Efficient Chromosome Biorientation in Budding Yeast Mitosis
inferred← citeshttps://doi.org/10.1371/journal.pgen.1000817openalex-snapshot
The MCM-Binding Protein ETG1 Aids Sister Chromatid Cohesion Required for Postreplicative Homologous Recombination Repair
inferred← citeshttps://doi.org/10.1371/journal.pone.0000053openalex-snapshot
PIASγ Is Required for Faithful Chromosome Segregation in Human Cells
inferred← citeshttps://doi.org/10.1371/journal.pone.0000318openalex-snapshot
Cohesin Is Dispensable for Centromere Cohesion in Human Cells
inferred← citeshttps://doi.org/10.1371/journal.pone.0003516openalex-snapshot
Shugoshin1 May Play Important Roles in Separation of Homologous Chromosomes and Sister Chromatids during Mouse Oocyte Meiosis
inferred← citeshttps://doi.org/10.1371/journal.pone.0073636openalex-snapshot
SGO1 Maintains Bovine Meiotic and Mitotic Centromeric Cohesions of Sister Chromatids and Directly Affects Embryo Development
inferred← citeshttps://doi.org/10.1371/journal.pone.0144673openalex-snapshot
Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1
inferred← citeshttps://doi.org/10.1371/journal.pone.0187660openalex-snapshot
Intravital longitudinal wide-area imaging of dynamic bone marrow engraftment and multilineage differentiation through nuclear-cytoplasmic labeling
inferred← citeshttps://doi.org/10.15252/embj.201695607openalex-snapshot
Drosophila Dalmatian combines sororin and shugoshin roles in establishment and protection of cohesion
inferred← citeshttps://doi.org/10.15252/embr.201744737openalex-snapshot
A kinase‐dependent role for Haspin in antagonizing Wapl and protecting mitotic centromere cohesion
inferred← citeshttps://doi.org/10.1534/genetics.105.048363openalex-snapshot
Sister Chromatids Are Often Incompletely Aligned in Meristematic and Endopolyploid Interphase Nuclei of Arabidopsis thaliana
inferred← citeshttps://doi.org/10.1586/eog.10.62openalex-snapshot
Advances in understanding the genetic causes and mechanisms of female germ cell aneuploidy
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