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Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.tem.2005.03.010openalex-snapshot
FoxO proteins in insulin action and metabolism
inferredcites →https://doi.org/10.1016/j.tibs.2004.12.002openalex-snapshot
Regulation of FoxO activity by CBP/p300-mediated acetylation
inferredcites →https://doi.org/10.1016/s0092-8674(00)80595-4openalex-snapshot
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
inferredcites →https://doi.org/10.1016/s0092-8674(04)00126-6openalex-snapshot
Mammalian SIRT1 Represses Forkhead Transcription Factors
inferredcites →https://doi.org/10.1016/s0092-8674(04)00452-0openalex-snapshot
FoxOs at the Crossroads of Cellular Metabolism, Differentiation, and Transformation
inferredcites →https://doi.org/10.1016/s0955-0674(00)00200-3openalex-snapshot
HATs on and beyond chromatin
inferredcites →https://doi.org/10.1038/19328openalex-snapshot
Direct control of the Forkhead transcription factor AFX by protein kinase B
inferredcites →https://doi.org/10.1042/0264-6021:3540605openalex-snapshot
Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting
inferredcites →https://doi.org/10.1042/bj20040167openalex-snapshot
The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation
inferredcites →https://doi.org/10.1073/pnas.0308762101openalex-snapshot
Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo
inferredcites →https://doi.org/10.1073/pnas.0400593101openalex-snapshot
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
inferredcites →https://doi.org/10.1073/pnas.0405454101openalex-snapshot
Proteasomal degradation of the FoxO1 transcriptional regulator in cells transformed by the P3k and Akt oncoproteins
inferredcites →https://doi.org/10.1073/pnas.0406789102openalex-snapshot
Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation
inferredcites →https://doi.org/10.1073/pnas.1934283100openalex-snapshot
Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation
inferredcites →https://doi.org/10.1073/pnas.90.22.10421openalex-snapshot
Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function.
inferredcites →https://doi.org/10.1073/pnas.96.13.7421openalex-snapshot
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
inferredcites →https://doi.org/10.1073/pnas.96.21.11836openalex-snapshot
Regulation of nuclear translocation of Forkhead transcription factor AFX by protein kinase B
inferredcites →https://doi.org/10.1074/jbc.274.24.17179openalex-snapshot
Phosphorylation of the Transcription Factor Forkhead Family Member FKHR by Protein Kinase B
inferredcites →https://doi.org/10.1074/jbc.c200578200openalex-snapshot
Acetylation of p53 Inhibits Its Ubiquitination by Mdm2
inferredcites →https://doi.org/10.1074/jbc.m208063200openalex-snapshot
Phosphorylation of Serine 256 Suppresses Transactivation by FKHR (FOXO1) by Multiple Mechanisms
inferredcites →https://doi.org/10.1074/jbc.m212570200openalex-snapshot
The Three Insulin Response Sequences in the Glucose-6-phosphatase Catalytic Subunit Gene Promoter Are Functionally Distinct
inferredcites →https://doi.org/10.1074/jbc.m213069200openalex-snapshot
Akt Activation Promotes Degradation of Tuberin and FOXO3a via the Proteasome
inferredcites →https://doi.org/10.1074/jbc.m401138200openalex-snapshot
FOXO4 Is Acetylated upon Peroxide Stress and Deacetylated by the Longevity Protein hSir2
inferredcites →https://doi.org/10.1074/jbc.m412357200openalex-snapshot
Nuclear Trapping of the Forkhead Transcription Factor FoxO1 via Sirt-dependent Deacetylation Promotes Expression of Glucogenetic Genes
inferredcites →https://doi.org/10.1093/emboj/19.5.989openalex-snapshot
Differential regulation of gene expression by insulin and IGF‐1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR
inferredcites →https://doi.org/10.1126/science.1094637openalex-snapshot
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
inferredcites →https://doi.org/10.1126/stke.2003.172.re5openalex-snapshot
The Many Forks in FOXO's Road
inferredcites →https://doi.org/10.2337/diabetes.52.3.642openalex-snapshot
Regulation of PGC-1 Promoter Activity by Protein Kinase B and the Forkhead Transcription Factor FKHR
inferredcites →https://doi.org/10.3892/ijmm.12.4.503openalex-snapshot
Negative regulation of forkhead transcription factor AFX (Foxo4) by CBP-induced acetylation
inferredcites →https://doi.org/10.3892/ijmm.9.2.147openalex-snapshot
Regulation of alkaline phosphatase promoter activity by forkhead transcription factor FKHR
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Differential Expression Profiles of Transfer RNA-Derived Small RNAs and Their Potential Roles in Diabetic Cardiomyopathy
inferred← citeshttps://doi.org/10.1002/1873-3468.13314openalex-snapshot
TRB 1 negatively regulates gluconeogenesis by suppressing the transcriptional activity of FOXO 1
inferred← citeshttps://doi.org/10.1002/1873-3468.15057openalex-snapshot
FoxO1 signaling in B cell malignancies and its therapeutic targeting
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Simvastatin inhibits cysteine‐rich protein 61 expression in rheumatoid arthritis synovial fibroblasts through the regulation of sirtuin‐1/FoxO3a signaling
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FOXO in aging: Did evolutionary diversification of FOXO function distract it from prolonging life?
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The downstream network of STAT6 in promoting vascular smooth muscle cell phenotypic switch and neointimal formation
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Electrochemical Aptasensor Based on Proximity‐Dependent Surface Hybridization Assay for Protein Detection
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MicroRNA‐146b promotes adipogenesis by suppressing the SIRT1‐FOXO1 cascade
inferred← citeshttps://doi.org/10.1002/ijc.24295openalex-snapshot
Hyperforin and aristoforin inhibit lymphatic endothelial cell proliferation in vitro and suppress tumor‐induced lymphangiogenesis in vivo
inferred← citeshttps://doi.org/10.1002/ijc.29979openalex-snapshot
HDAC5 controls the functions of Foxp3+ T‐regulatory and CD8+ T cells
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2014.tb00548.xopenalex-snapshot
Energy Metabolism in the Liver
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Acetyltransferases CBP/p300 Control Transcriptional Switch of β-Catenin and Stat1 Promoting Osteoblast Differentiation
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Genistein suppresses ox‐LDL‐elicited oxidative stress and senescence in HUVECs through the SIRT1‐p66shc‐Foxo3a pathways
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The influential responsibility of sirtuins in senescence and associated diseases: A review
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Regulation of lysyl oxidase expression in THP‐1 cell‐derived M2‐like macrophages
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Regulation of autophagy by protein methylation and acetylation in cancer
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Maternal Obesity Programs Adipogenic Commitment in Neonatal Mesenchymal Stem Cells: A Link to Redox‐Dependent FOXO1 Signaling
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A “FOXO” in sight: Targeting Foxo proteins from conception to cancer
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The role of FOXOs and autophagy in cancer and metastasis—Implications in therapeutic development
inferred← citeshttps://doi.org/10.1002/mgg3.602openalex-snapshot
HDAC4 mutations cause diabetes and induce β‐cell FoxO1 nuclear exclusion
inferred← citeshttps://doi.org/10.1007/1-4020-5466-1_9openalex-snapshot
Reversible Acetylation Of Non Histone Proteins
inferred← citeshttps://doi.org/10.1007/7355_2019_71openalex-snapshot
Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors
inferred← citeshttps://doi.org/10.1007/978-1-4419-1599-3_11openalex-snapshot
New Insights for FOXO and Cell-Fate Decision in HIV Infection and HIV Associated Neurocognitive Disorder
inferred← citeshttps://doi.org/10.1007/978-1-4419-1599-3_18openalex-snapshot
The “O” Class: Crafting Clinical Care with FoxO Transcription Factors
inferred← citeshttps://doi.org/10.1007/978-1-4419-1599-3_6openalex-snapshot
FoxO Proteins and Cardiac Pathology
inferred← citeshttps://doi.org/10.1007/978-1-4614-6438-9_101601-1openalex-snapshot
Forkhead Box Protein O
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Role of PI3K–Akt and PTEN in the Growth and Progression of Prostate Cancer
inferred← citeshttps://doi.org/10.1007/978-1-60761-602-3_9openalex-snapshot
Novel Strategies for Neurovascular Longevity During Aging
inferred← citeshttps://doi.org/10.1007/978-3-319-41457-7_10openalex-snapshot
Cardiac Autophagy and Its Regulation by Reversible Protein Acetylation
inferred← citeshttps://doi.org/10.1007/978-3-319-67199-4_101601openalex-snapshot
Forkhead Box Protein O
inferred← citeshttps://doi.org/10.1007/978-3-7091-1824-5_3openalex-snapshot
Autophagy and Tumor Cell Metabolism
inferred← citeshttps://doi.org/10.1007/s00011-014-0780-yopenalex-snapshot
Role of farnesoid X receptor in inflammation and resolution
inferred← citeshttps://doi.org/10.1007/s00109-022-02219-xopenalex-snapshot
The FOXO family of transcription factors: key molecular players in gastric cancer
inferred← citeshttps://doi.org/10.1007/s00109-022-02281-5openalex-snapshot
FoxO3 and oxidative stress: a multifaceted role in cellular adaptation
inferred← citeshttps://doi.org/10.1007/s10495-016-1341-3openalex-snapshot
SIRT2-mediated FOXO3a deacetylation drives its nuclear translocation triggering FasL-induced cell apoptosis during renal ischemia reperfusion
inferred← citeshttps://doi.org/10.1007/s10495-023-01924-3openalex-snapshot
Acetylation of FOXO1 activates Bim expression involved in CVB3 induced cardiomyocyte apoptosis
inferred← citeshttps://doi.org/10.1007/s10522-014-9519-yopenalex-snapshot
The roles of FoxOs in modulation of aging by calorie restriction
inferred← citeshttps://doi.org/10.1007/s10522-017-9685-9openalex-snapshot
Sirtuins, a promising target in slowing down the ageing process
inferred← citeshttps://doi.org/10.1007/s10522-020-09864-0openalex-snapshot
The crosstalk of NAD, ROS and autophagy in cellular health and ageing
inferred← citeshttps://doi.org/10.1007/s10555-020-09883-wopenalex-snapshot
FOXO transcription factor family in cancer and metastasis
inferred← citeshttps://doi.org/10.1007/s10555-022-10077-9openalex-snapshot
Involvement of redox signalling in tumour cell dormancy and metastasis
inferred← citeshttps://doi.org/10.1007/s10565-020-09556-yopenalex-snapshot
In vitro study of the role of FOXO transcription factors in regulating cigarette smoke extract-induced autophagy
inferred← citeshttps://doi.org/10.1007/s11010-018-3392-yopenalex-snapshot
Maresin 1 attenuates pro-inflammatory reactions and ER stress in HUVECs via PPARα-mediated pathway
inferred← citeshttps://doi.org/10.1007/s11064-021-03364-4openalex-snapshot
Elucidating the Possible Role of FoxO in Depression
inferred← citeshttps://doi.org/10.1007/s12013-025-01903-2openalex-snapshot
Linking SIRT1 Variants to Metabolic and Cardiovascular Phenotypes: Insights from Population Genetics and In Silico Structural Analysis
inferred← citeshttps://doi.org/10.1007/s12265-010-9200-zopenalex-snapshot
FoxO, Autophagy, and Cardiac Remodeling
inferred← citeshttps://doi.org/10.1007/s13238-015-0204-yopenalex-snapshot
Role of transcription factor acetylation in the regulation of metabolic homeostasis
inferred← citeshttps://doi.org/10.1007/s13258-017-0593-9openalex-snapshot
Bioinformatic prediction and analysis of glucolipid metabolic regulation by miR-34a in Megalobrama amblycephala
inferred← citeshttps://doi.org/10.1007/s13277-015-3215-7openalex-snapshot
Posttranslational modifications of FOXO1 regulate epidermal growth factor receptor tyrosine kinase inhibitor resistance for non-small cell lung cancer cells
inferred← citeshttps://doi.org/10.1007/s13277-015-4297-yopenalex-snapshot
Involvement of Numb-mediated HIF-1α inhibition in anti-proliferative effect of PNA-antimiR-182 in trastuzumab-sensitive and -resistant SKBR3 cells
inferred← citeshttps://doi.org/10.1007/s44307-024-00027-7openalex-snapshot
Acetylation modification in the regulation of macroautophagy
inferred← citeshttps://doi.org/10.1016/b978-0-12-801816-3.00015-7openalex-snapshot
Aging and Its Dietary Modulation by FoxO1 Phosphorylation/Acetylation
inferred← citeshttps://doi.org/10.1016/b978-0-12-809965-0.00010-0openalex-snapshot
Diverse Mechanisms of Transcriptional Regulation by the Vitamin D Receptor
inferred← citeshttps://doi.org/10.1016/b978-0-12-814118-2.00001-xopenalex-snapshot
Novel treatment strategies for neurodegenerative disease with sirtuins
inferred← citeshttps://doi.org/10.1016/b978-0-12-816422-8.00003-9openalex-snapshot
HAT inhibitors in cancer therapy
inferred← citeshttps://doi.org/10.1016/b978-0-323-91386-7.00043-xopenalex-snapshot
The diverse genomic mechanisms of action of the vitamin D receptor
inferred← citeshttps://doi.org/10.1016/b978-0-323-91704-9.00018-5openalex-snapshot
Liver metabolism: the pathways underlying glucose utilization and production
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2017.10.005openalex-snapshot
Regulation of Hepatic Glucose Metabolism by FoxO Proteins, an Integrated Approach
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2017.10.006openalex-snapshot
Regulation of FOXO Factors in Mammalian Cells
inferred← citeshttps://doi.org/10.1016/bs.ircmb.2015.05.004openalex-snapshot
Insights into Transcriptional Regulation of Hepatic Glucose Production
inferred← citeshttps://doi.org/10.1016/j.apsb.2024.05.027openalex-snapshot
Aloe emodin promotes mucosal healing by modifying the differentiation fate of enteroendocrine cells via regulating cellular free fatty acid sensitivity
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2018.10.014openalex-snapshot
MiR-34a regulates the glucose metabolism of Blunt snout bream (Megalobrama amblycephala) fed high-carbohydrate diets through the mediation of the Sirt1/FoxO1 axis
inferred← citeshttps://doi.org/10.1016/j.autrev.2025.103878openalex-snapshot
The FOXO1-SIRT1 axis in ankylosing spondylitis: A cross-platform regulator linking immunometabolism, oxidative stress, and bone remodeling
inferred← citeshttps://doi.org/10.1016/j.bbadis.2010.11.011openalex-snapshot
Regulation of FXR transcriptional activity in health and disease: Emerging roles of FXR cofactors and post-translational modifications
inferred← citeshttps://doi.org/10.1016/j.bbadis.2016.08.011openalex-snapshot
Mechanisms of transcription factor acetylation and consequences in hearts
inferred← citeshttps://doi.org/10.1016/j.bbadis.2021.166261openalex-snapshot
Enhancing Acsl4 in absence of mTORC2/Rictor drove β-cell dedifferentiation via inhibiting FoxO1 and promoting ROS production
inferred← citeshttps://doi.org/10.1016/j.bbadis.2024.167129openalex-snapshot
Spinal sirtuin 2 attenuates bone cancer pain by deacetylating FoxO3a
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2010.10.002openalex-snapshot
Protein lysine acetylation in cellular function and its role in cancer manifestation
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2016.01.006openalex-snapshot
Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2019.04.001openalex-snapshot
Zbtb7c is a critical gluconeogenic transcription factor that induces glucose-6-phosphatase and phosphoenylpyruvate carboxykinase 1 genes expression during mice fasting
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2010.11.025openalex-snapshot
Structural basis for DNA recognition by FOXO proteins
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2011.01.029openalex-snapshot
Mitochondrial longevity pathways
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2011.02.008openalex-snapshot
CNK1 and other scaffolds for Akt/FoxO signaling
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2011.03.001openalex-snapshot
Regulation of FoxO transcription factors by acetylation and protein–protein interactions
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2011.06.002openalex-snapshot
FoxO transcription factors; Regulation by AKT and 14-3-3 proteins
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2018.01.007openalex-snapshot
Ras-Raf-MAPK signaling promotes nuclear localization of FOXA transcription factor SGF1 via Ser91 phosphorylation
inferred← citeshttps://doi.org/10.1016/j.bbcan.2007.10.003openalex-snapshot
FoxO tumor suppressors and BCR–ABL-induced leukemia: A matter of evasion of apoptosis
inferred← citeshttps://doi.org/10.1016/j.bbcan.2024.189083openalex-snapshot
Mechanistic regulation of FOXO transcription factors in the nucleus
inferred← citeshttps://doi.org/10.1016/j.bbrc.2009.01.014openalex-snapshot
Acetylation curtails nucleosome binding, not stable nucleosome remodeling, by FoxO1
inferred← citeshttps://doi.org/10.1016/j.bbrc.2010.11.028openalex-snapshot
Role of resveratrol in FOXO1-mediated gluconeogenic gene expression in the liver
inferred← citeshttps://doi.org/10.1016/j.bbrc.2021.03.122openalex-snapshot
Resveratrol attenuates radiation enteritis through the SIRT1/FOXO3a and PI3K/AKT signaling pathways
inferred← citeshttps://doi.org/10.1016/j.biocel.2011.10.001openalex-snapshot
Transcription factors and coactivators controlling nutrient and hormonal regulation of hepatic gluconeogenesis
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116802openalex-snapshot
Potential role of molecular hydrogen therapy on oxidative stress and redox signaling in chronic kidney disease
inferred← citeshttps://doi.org/10.1016/j.bpc.2013.09.002openalex-snapshot
Detailed kinetic analysis of the interaction between the FOXO4–DNA-binding domain and DNA
inferred← citeshttps://doi.org/10.1016/j.ceb.2008.02.005openalex-snapshot
FoxO transcription factors in the maintenance of cellular homeostasis during aging
inferred← citeshttps://doi.org/10.1016/j.cell.2011.03.043openalex-snapshot
Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis
inferred← citeshttps://doi.org/10.1016/j.cell.2011.04.013openalex-snapshot
A Hormone-Dependent Module Regulating Energy Balance
inferred← citeshttps://doi.org/10.1016/j.cell.2012.05.038openalex-snapshot
Acetylation-Dependent Regulation of Skp2 Function
inferred← citeshttps://doi.org/10.1016/j.cell.2015.04.025openalex-snapshot
A Receptor Pair with an Integrated Decoy Converts Pathogen Disabling of Transcription Factors to Immunity
inferred← citeshttps://doi.org/10.1016/j.cellsig.2008.12.004openalex-snapshot
Tubulin acetylation favors Hsp90 recruitment to microtubules and stimulates the signaling function of the Hsp90 clients Akt/PKB and p53
inferred← citeshttps://doi.org/10.1016/j.cellsig.2012.10.002openalex-snapshot
Beside the MEF2 axis: Unconventional functions of HDAC4
inferred← citeshttps://doi.org/10.1016/j.cellsig.2015.08.013openalex-snapshot
SIRT1 contributes to aldose reductase expression through modulating NFAT5 under osmotic stress: In vitro and in silico insights
inferred← citeshttps://doi.org/10.1016/j.cellsig.2016.05.011openalex-snapshot
Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.02.035openalex-snapshot
Ets1-Mediated Acetylation of FoxO1 Is Critical for Gluconeogenesis Regulation during Feed-Fast Cycles
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.114272openalex-snapshot
Decrypting lysine deacetylase inhibitor action and protein modifications by dose-resolved proteomics
inferred← citeshttps://doi.org/10.1016/j.cmet.2007.07.003openalex-snapshot
SIRT2 Regulates Adipocyte Differentiation through FoxO1 Acetylation/Deacetylation
inferred← citeshttps://doi.org/10.1016/j.cmet.2017.12.014openalex-snapshot
Metabolic Reprogramming via Targeting CD38 NADase Augments Adoptive T Cell Therapy
inferred← citeshttps://doi.org/10.1016/j.coi.2007.07.015openalex-snapshot
Histone deacetylase inhibitors and transplantation
inferred← citeshttps://doi.org/10.1016/j.devcel.2020.06.035openalex-snapshot
Exploring the Influence of Cell Metabolism on Cell Fate through Protein Post-translational Modifications
inferred← citeshttps://doi.org/10.1016/j.drup.2010.12.001openalex-snapshot
Interplay between SIRT proteins and tumour suppressor transcription factors in chemotherapeutic resistance of cancer
inferred← citeshttps://doi.org/10.1016/j.ejphar.2010.07.018openalex-snapshot
Effects of the novel Foxo1 inhibitor AS1708727 on plasma glucose and triglyceride levels in diabetic db/db mice
inferred← citeshttps://doi.org/10.1016/j.ejphar.2020.173758openalex-snapshot
FoxO1 signaling as a therapeutic target for type 2 diabetes and obesity
inferred← citeshttps://doi.org/10.1016/j.exger.2008.05.011openalex-snapshot
Calorie restriction minimizes activation of insulin signaling in response to glucose: Potential involvement of the growth hormone-insulin-like growth factor 1 axis
inferred← citeshttps://doi.org/10.1016/j.exger.2010.01.004openalex-snapshot
Oxidative stress: Biomarkers and novel therapeutic pathways
inferred← citeshttps://doi.org/10.1016/j.exphem.2019.10.004openalex-snapshot
Depletion of the transcriptional coactivators CREB-binding protein or EP300 downregulates CD20 in diffuse large B-cell lymphoma cells and impairs the cytotoxic effects of anti-CD20 antibodies
inferred← citeshttps://doi.org/10.1016/j.febslet.2007.11.025openalex-snapshot
The FoxO transcription factors and metabolic regulation
inferred← citeshttps://doi.org/10.1016/j.febslet.2014.06.053openalex-snapshot
Inhibition of FoxO1 acetylation by INHAT subunit SET/TAF‐Iβ induces p21 transcription
inferred← citeshttps://doi.org/10.1016/j.foodchem.2021.129696openalex-snapshot
Effects of acetylation on dissociation and phosphorylation of actomyosin in postmortem ovine muscle during incubation at 4 °C in vitro
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2013.05.002openalex-snapshot
SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.12.016openalex-snapshot
Quercetin induces autophagy via FOXO1-dependent pathways and autophagy suppression enhances quercetin-induced apoptosis in PASMCs in hypoxia
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.02.034openalex-snapshot
FOXO1 cysteine-612 mediates stimulatory effects of the coregulators CBP and PGC1α on FOXO1 basal transcriptional activity
inferred← citeshttps://doi.org/10.1016/j.gene.2010.03.008openalex-snapshot
Isolation of putative FOXO1 genomic elements using an improved in vitro technique to isolate genomic regulatory sequences
inferred← citeshttps://doi.org/10.1016/j.gene.2023.147672openalex-snapshot
Birth and death view of DNA, RNA, and proteins
inferred← citeshttps://doi.org/10.1016/j.ibmb.2023.103907openalex-snapshot
FoxO directly regulates the expression of odorant receptor genes to govern olfactory plasticity upon starvation in Bactrocera dorsalis
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2023.126025openalex-snapshot
FOXO1 regulates the formation of bovine fat by targeting CD36 and STEAP4
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.143119openalex-snapshot
Acetylation of Hsc70 at K512 inhibits goat ovarian granulosa cell senescence by restoring chaperone-mediated autophagy
inferred← citeshttps://doi.org/10.1016/j.ijcard.2017.07.096openalex-snapshot
The impact of FOXO-1 to cardiac pathology in diabetes mellitus and diabetes-related metabolic abnormalities
inferred← citeshttps://doi.org/10.1016/j.immuni.2021.07.009openalex-snapshot
Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113116openalex-snapshot
Ginkgolide A enhances FoxO1 expression and reduces endoplasmic reticulum stress to mitigate osteoarthritis in mice
inferred← citeshttps://doi.org/10.1016/j.isci.2019.100798openalex-snapshot
FCoR-Foxo1 Axis Regulates α-Cell Mass through Repression of Arx Expression
inferred← citeshttps://doi.org/10.1016/j.jbc.2024.107209openalex-snapshot
FOXO1 promotes cancer cell growth through MDM2-mediated p53 degradation
inferred← citeshttps://doi.org/10.1016/j.jmb.2021.166808openalex-snapshot
FOXO4 Transactivation Domain Interaction with Forkhead DNA Binding Domain and Effect on Selective DNA Recognition for Transcription Initiation
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2011.07.008openalex-snapshot
Modulation of FoxO1 phosphorylation/acetylation by baicalin during aging
inferred← citeshttps://doi.org/10.1016/j.joca.2021.07.015openalex-snapshot
TGFβ1 signaling protects chondrocytes against oxidative stress via FOXO1–autophagy axis
inferred← citeshttps://doi.org/10.1016/j.jot.2024.11.008openalex-snapshot
Sirt1 blocks nucleus pulposus and macrophages crosstalk by inhibiting RelA/Lipocalin 2 axis
inferred← citeshttps://doi.org/10.1016/j.jprot.2017.04.003openalex-snapshot
Understanding Alzheimer's disease by global quantification of protein phosphorylation and sialylated N-linked glycosylation profiles: A chance for new biomarkers in neuroproteomics?
inferred← citeshttps://doi.org/10.1016/j.jsbmb.2013.07.012openalex-snapshot
Non-classical mechanisms of transcriptional regulation by the vitamin D receptor: Insights into calcium homeostasis, immune system regulation and cancer chemoprevention
inferred← citeshttps://doi.org/10.1016/j.lfs.2020.118173openalex-snapshot
Flavonoids-mediated SIRT1 signaling activation in hepatic disorders
inferred← citeshttps://doi.org/10.1016/j.livres.2017.11.004openalex-snapshot
FOXO transcription factors in non-alcoholic fatty liver disease
inferred← citeshttps://doi.org/10.1016/j.mam.2015.09.003openalex-snapshot
Molecular pathophysiology of hepatic glucose production
inferred← citeshttps://doi.org/10.1016/j.mce.2012.05.011openalex-snapshot
Protein acetylation mechanisms in the regulation of insulin and insulin-like growth factor 1 signalling
inferred← citeshttps://doi.org/10.1016/j.mce.2015.02.006openalex-snapshot
FOXO1 is regulated by insulin and IGF1 in pituitary gonadotropes
inferred← citeshttps://doi.org/10.1016/j.mce.2018.02.015openalex-snapshot
SIRT1 suppresses high glucose and palmitate-induced osteoclast differentiation via deacetylating p66Shc
inferred← citeshttps://doi.org/10.1016/j.mcpro.2026.101619openalex-snapshot
A Temporal Phospho-acetylome Atlas of Human Myogenesis Identifies coordinated Post-Translational Regulation
inferred← citeshttps://doi.org/10.1016/j.molcel.2008.07.002openalex-snapshot
Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications
inferred← citeshttps://doi.org/10.1016/j.molcel.2008.09.013openalex-snapshot
Arginine Methylation of FOXO Transcription Factors Inhibits Their Phosphorylation by Akt
inferred← citeshttps://doi.org/10.1016/j.molcel.2026.03.020openalex-snapshot
FOXF1/2 establish a senescence-specific enhancer landscape to activate the pro-inflammatory senescence-associated secretory phenotype
inferred← citeshttps://doi.org/10.1016/j.molp.2025.08.002openalex-snapshot
HDT2-mediated lysine deacetylation promotes phytochrome A degradation during photomorphogenesis in Arabidopsis
inferred← citeshttps://doi.org/10.1016/j.pharep.2017.02.005openalex-snapshot
Esculetin ameliorates hepatic fibrosis in high fat diet induced non-alcoholic fatty liver disease by regulation of FoxO1 mediated pathway
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2006.07.004openalex-snapshot
The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2012.08.009openalex-snapshot
SIRT1 in metabolic syndrome: Where to target matters
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2025.108908openalex-snapshot
The role of lysine acetylation in metabolic sensing and proteostasis
inferred← citeshttps://doi.org/10.1016/j.phrs.2026.108122openalex-snapshot
Targeting FoxO1 in cardiovascular diseases: Mechanisms and therapeutic potential
inferred← citeshttps://doi.org/10.1016/j.placenta.2008.12.008openalex-snapshot
Localisation and Expression of FoxO1 Proteins in Human Gestational Tissues
inferred← citeshttps://doi.org/10.1016/j.plipres.2017.04.002openalex-snapshot
A global perspective on FOXO1 in lipid metabolism and lipid-related diseases
inferred← citeshttps://doi.org/10.1016/j.pneurobio.2019.101645openalex-snapshot
Roles of forkhead box O (FoxO) transcription factors in neurodegenerative diseases: A panoramic view
inferred← citeshttps://doi.org/10.1016/j.prp.2026.156527openalex-snapshot
Licochalcone A targets ADRB2 to enhance CD8+ T cell anti-leukemia activity via regulation involving the AKT2/FOXO1/GLUT2 axis
inferred← citeshttps://doi.org/10.1016/j.redox.2015.06.019openalex-snapshot
Redox regulation of FoxO transcription factors
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.174543openalex-snapshot
Insights into the role of FoxL2 in tebuconazole-induced male- biased sex differentiation of zebrafish
inferred← citeshttps://doi.org/10.1016/j.semcancer.2017.07.007openalex-snapshot
Role of Forkhead Box Class O proteins in cancer progression and metastasis
inferred← citeshttps://doi.org/10.1016/j.semcancer.2017.11.006openalex-snapshot
PAX3-FOXO1: Zooming in on an “undruggable” target
inferred← citeshttps://doi.org/10.1016/j.semcancer.2017.11.007openalex-snapshot
Mechanisms controlling the anti-neoplastic functions of FoxO proteins
inferred← citeshttps://doi.org/10.1016/j.semcancer.2018.01.004openalex-snapshot
FoxO transcription factors in cancer metabolism
inferred← citeshttps://doi.org/10.1016/j.semcancer.2018.01.011openalex-snapshot
Homeostatic interplay between FoxO proteins and ER proteostasis in cancer and other diseases
inferred← citeshttps://doi.org/10.1016/j.semcancer.2021.03.001openalex-snapshot
Targeting the acetylation signaling pathway in cancer therapy
inferred← citeshttps://doi.org/10.1016/j.stem.2007.07.017openalex-snapshot
FoxO Transcription Factors and Stem Cell Homeostasis: Insights from the Hematopoietic System
inferred← citeshttps://doi.org/10.1016/j.str.2008.06.013openalex-snapshot
Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification
inferred← citeshttps://doi.org/10.1016/j.tcb.2016.01.002openalex-snapshot
Nuclear Mechanisms of Insulin Resistance
inferred← citeshttps://doi.org/10.1016/j.tips.2013.11.005openalex-snapshot
Regulation of transcription factor activity by interconnected post-translational modifications
inferred← citeshttps://doi.org/10.1016/j.yexcr.2021.112612openalex-snapshot
PDGF-BB-mediated activation of CREB in vascular smooth muscle cells alters cell cycling via Rb, FoxO1 and p27kip1
inferred← citeshttps://doi.org/10.1021/acs.analchem.1c02808openalex-snapshot
Evaluation of FOXO1 Target Engagement Using a Single-Cell Microfluidic Platform
inferred← citeshttps://doi.org/10.1021/acs.biochem.6c00040openalex-snapshot
PAX3-FOXO1 Contacts BRD4 through Its Acetylated Intrinsically Disordered Region
inferred← citeshttps://doi.org/10.1021/bi1004427openalex-snapshot
Acetylation of GAGA Factor Modulates Its Interaction with DNA
inferred← citeshttps://doi.org/10.1038/bcj.2015.89openalex-snapshot
Mutation of chromatin modifiers; an emerging hallmark of germinal center B-cell lymphomas
inferred← citeshttps://doi.org/10.1038/cddis.2013.91openalex-snapshot
The E3 ubiquitin ligase Itch regulates tumor suppressor protein RASSF5/NORE1 stability in an acetylation-dependent manner
inferred← citeshttps://doi.org/10.1038/emboj.2012.116openalex-snapshot
Putting the brakes on FOXO1 in fat
inferred← citeshttps://doi.org/10.1038/embor.2012.25openalex-snapshot
Lysine methylation of FOXO3 regulates oxidative stress‐induced neuronal cell death
inferred← citeshttps://doi.org/10.1038/icb.2008.106openalex-snapshot
Using histone deacetylase inhibitors to enhance Foxp3+ regulatory T‐cell function and induce allograft tolerance
inferred← citeshttps://doi.org/10.1038/leu.2008.186openalex-snapshot
Acetylation of FOXO3a transcription factor in response to imatinib of chronic myeloid leukemia
inferred← citeshttps://doi.org/10.1038/nchembio.194openalex-snapshot
Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity
inferred← citeshttps://doi.org/10.1038/ncomms10968openalex-snapshot
Acetylation of C/EBPα inhibits its granulopoietic function
inferred← citeshttps://doi.org/10.1038/nm.3085openalex-snapshot
Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis
inferred← citeshttps://doi.org/10.1038/nm1652openalex-snapshot
Deacetylase inhibition promotes the generation and function of regulatory T cells
inferred← citeshttps://doi.org/10.1038/nn.4347openalex-snapshot
Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior
inferred← citeshttps://doi.org/10.1038/nri3278openalex-snapshot
FOXO transcription factors throughout T cell biology
inferred← citeshttps://doi.org/10.1038/nrm2190openalex-snapshot
Stressing the role of FoxO proteins in lifespan and disease
inferred← citeshttps://doi.org/10.1038/nrm3841openalex-snapshot
The growing landscape of lysine acetylation links metabolism and cell signalling
inferred← citeshttps://doi.org/10.1038/nsmb.1583openalex-snapshot
Acetylation by GCN5 regulates CDC6 phosphorylation in the S phase of the cell cycle
inferred← citeshttps://doi.org/10.1038/onc.2008.20openalex-snapshot
Structure/function relationships underlying regulation of FOXO transcription factors
inferred← citeshttps://doi.org/10.1038/onc.2011.347openalex-snapshot
Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation
inferred← citeshttps://doi.org/10.1038/onc.2011.45openalex-snapshot
Epigenetic regulation of aging stem cells
inferred← citeshttps://doi.org/10.1038/onc.2013.88openalex-snapshot
SIRT1 regulates YAP2-mediated cell proliferation and chemoresistance in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1038/s12276-021-00589-9openalex-snapshot
Sublytic C5b-9 induces glomerular mesangial cell proliferation via ERK1/2-dependent SOX9 phosphorylation and acetylation by enhancing Cyclin D1 in rat Thy-1 nephritis
inferred← citeshttps://doi.org/10.1038/s41388-023-02592-yopenalex-snapshot
NAD+ supplementation limits triple-negative breast cancer metastasis via SIRT1-P66Shc signaling
inferred← citeshttps://doi.org/10.1038/s41392-022-01245-yopenalex-snapshot
Protein acylation: mechanisms, biological functions and therapeutic targets
inferred← citeshttps://doi.org/10.1038/s41392-022-01300-8openalex-snapshot
Epigenetic and post-translational modifications in autophagy: biological functions and therapeutic targets
inferred← citeshttps://doi.org/10.1038/s41418-022-01065-1openalex-snapshot
NCOR1 maintains the homeostasis of vascular smooth muscle cells and protects against aortic aneurysm
inferred← citeshttps://doi.org/10.1038/s41419-020-02960-6openalex-snapshot
Selective inhibition of CBP/p300 HAT by A-485 results in suppression of lipogenesis and hepatic gluconeogenesis
inferred← citeshttps://doi.org/10.1038/s41419-023-05932-8openalex-snapshot
ATP-citrate lyase controls endothelial gluco-lipogenic metabolism and vascular inflammation in sepsis-associated organ injury
inferred← citeshttps://doi.org/10.1038/s41419-024-07177-5openalex-snapshot
Metformin improves HPRT1-targeted purine metabolism and repairs NR4A1-mediated autophagic flux by modulating FoxO1 nucleocytoplasmic shuttling to treat postmenopausal osteoporosis
inferred← citeshttps://doi.org/10.1038/s41423-025-01294-7openalex-snapshot
Malonate promotes CD8+ T cell memory formation via protein malonylation
inferred← citeshttps://doi.org/10.1038/s41467-017-01112-3openalex-snapshot
Role of influenza A virus NP acetylation on viral growth and replication
inferred← citeshttps://doi.org/10.1038/s41467-019-10025-2openalex-snapshot
Lnc-TALC promotes O6-methylguanine-DNA methyltransferase expression via regulating the c-Met pathway by competitively binding with miR-20b-3p
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