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The unique cytoarchitecture of human pancreatic islets has implications for islet cell function

https://doi.org/10.1073/pnas.0510790103
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/bf00251826openalex-snapshot
Cellular composition of the human diabetic pancreas
inferredcites →https://doi.org/10.1007/bf00550880openalex-snapshot
Widespread synchronous [Ca2+]i oscillations due to bursting electrical activity in single pancreatic islets
inferredcites →https://doi.org/10.1007/s125-002-8248-zopenalex-snapshot
Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients
inferredcites →https://doi.org/10.1016/0014-5793(89)81484-xopenalex-snapshot
Glucose‐induced oscillations of intracellular Ca2+ concentration resembling bursting electrical activity in single mouse islets of Langerhans
inferredcites →https://doi.org/10.1016/0024-3205(76)90112-0openalex-snapshot
Pancreatic polypeptide and glucagon: Non-random distribution in pancreatic islets
inferredcites →https://doi.org/10.1016/s0025-6196(11)62275-1openalex-snapshot
Endocrinology: An Integrated Approach
inferredcites →https://doi.org/10.1016/s0031-3025(16)34850-4openalex-snapshot
Functional endocrine pathology
inferredcites →https://doi.org/10.1016/s0065-1281(11)80167-4openalex-snapshot
A morphological and immunohistochemical investigation of endocrine pancreata from obese ob+/ob+ mice
inferredcites →https://doi.org/10.1016/s0140-6736(75)92078-4openalex-snapshot
FUNCTIONAL SUBDIVISION OF ISLETS OF LANGERHANS AND POSSIBLE ROLE OF D CELLS
inferredcites →https://doi.org/10.1016/s0940-2993(98)80078-xopenalex-snapshot
A comparative immunohistochemical study of pancreatic islets inlaboratory animals (rats, dogs, minipigs, nonhuman primates)
inferredcites →https://doi.org/10.1046/j.1439-0264.1999.00148.xopenalex-snapshot
Proportions of Various Endocrine Cells in the Pancreatic Islets of Wood Mice (Apodemus speciosus)
inferredcites →https://doi.org/10.1073/pnas.96.14.8132openalex-snapshot
Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154
inferredcites →https://doi.org/10.1097/00006676-199201000-00005openalex-snapshot
Perfusion with Anti-Insulin Gamma Globulin Indicates a B to A to D Cellular Perfusion Sequence in the Pancreas of the Rhesus Monkey, Macaca mulatta
inferredcites →https://doi.org/10.1097/00006676-199511000-00012openalex-snapshot
Quantitative Immunohistochemical Changes in the Endocrine Pancreas of Nonobese Diabetic (NOD) Mice
inferredcites →https://doi.org/10.1097/00007890-198809000-00027openalex-snapshot
A NEW, SIMPLE METHOD FOR COLD STORAGE OF THE PANCREAS USING PERFLUOROCHEMICAL
inferredcites →https://doi.org/10.1097/00007890-198810000-00004openalex-snapshot
PANCREATIC SECRETORY TRYPSIN INHIBITOR AS A MARKER FOR EARLY DETECTION OF REJECTION IN CANINE PANCREAS ALLOTRANSPLANTATION
inferredcites →https://doi.org/10.1097/00007890-200101150-00020openalex-snapshot
ENDOTOXIN-MEDIATED DELAYED ISLET GRAFT FUNCTION IS ASSOCIATED WITH INCREASED INTRA-ISLET CYTOKINE PRODUCTION AND ISLET CELL APOPTOSIS1
inferredcites →https://doi.org/10.1111/j.1469-7793.1999.0085z.xopenalex-snapshot
Homologous and heterologous asynchronicity between identified α‐, β‐ and δ‐cells within intact islets of Langerhans in the mouse
inferredcites →https://doi.org/10.1111/j.1600-6143.2005.00913.xopenalex-snapshot
A Novel Method for the Assessment of Cellular Composition and Beta-Cell Viability in Human Islet Preparations
inferredcites →https://doi.org/10.1172/jci114574openalex-snapshot
Islets of Langerhans: the puzzle of intraislet interactions and their relevance to diabetes.
inferredcites →https://doi.org/10.1369/jhc.5c6684.2005openalex-snapshot
Assessment of Human Pancreatic Islet Architecture and Composition by Laser Scanning Confocal Microscopy
inferredcites →https://doi.org/10.2337/diab.31.10.883openalex-snapshot
New Perspectives on the Microvasculature of the Islets of Langerhans in the Rat
inferredcites →https://doi.org/10.2337/diab.31.8.694openalex-snapshot
Quantitation of Endocrine Cell Content in the Pancreas of Nondiabetic and Diabetic Humans
inferredcites →https://doi.org/10.2337/diab.37.4.413openalex-snapshot
Automated Method for Isolation of Human Pancreatic Islets
inferredcites →https://doi.org/10.2337/diab.38.6.808openalex-snapshot
Three-Dimensional Imaging of Intact Isolated Islets of Langerhans With Confocal Microscopy
inferredcites →https://doi.org/10.2337/diab.45.4.385openalex-snapshot
Microcirculation of the Islets of Langerhans: Long Beach Veterans Administration Regional Medical Education Center Symposium
inferredcites →https://doi.org/10.2337/diabetes.48.12.2390openalex-snapshot
Different effects of tolbutamide and diazoxide in alpha, beta-, and delta-cells within intact islets of Langerhans.
inferredcites →https://doi.org/10.2337/diabetes.53.12.3107openalex-snapshot
Islet Graft Assessment in the Edmonton Protocol
inferredcites →https://doi.org/10.2337/diabetes.54.6.1798openalex-snapshot
Loss of Connexin36 Channels Alters β-Cell Coupling, Islet Synchronization of Glucose-Induced Ca2+ and Insulin Oscillations, and Basal Insulin Release

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3155818openalex-extracted
Local Integrin Activation in Pancreatic ß Cells Targets Insulin Secretion to the Vasculature
inferred← citeshttps://doi.org/10.2139/ssrn.3273389openalex-extracted
Glucagon Switches between GLP-1 and Glucagon Receptors in Normal and Hyperglycemic Mice
inferred← citeshttps://doi.org/10.1001/jama.2009.482openalex-snapshot
Human Pancreatic Islets and Diabetes Research
inferred← citeshttps://doi.org/10.1002/9781118387658.ch24openalex-snapshot
β‐Cell mass and function in human type 2 diabetes
inferred← citeshttps://doi.org/10.1002/9781118387658.ch5openalex-snapshot
Pancreatic morphology in normal and diabetic states
inferred← citeshttps://doi.org/10.1002/9781118903681.ch7openalex-snapshot
Endocrine Therapeutic Delivery
inferred← citeshttps://doi.org/10.1002/9781118924853.ch6openalex-snapshot
Islet Function and Insulin Secretion
inferred← citeshttps://doi.org/10.1002/9781118924853.ch7openalex-snapshot
Glucagon in Islet and Metabolic Regulation
inferred← citeshttps://doi.org/10.1002/9781119697473.ch7openalex-snapshot
Islet Function and Insulin Secretion
inferred← citeshttps://doi.org/10.1002/9781119697473.ch8openalex-snapshot
Glucagon in Islet and Metabolic Regulation
inferred← citeshttps://doi.org/10.1002/9781444316728.ch19openalex-snapshot
Hypoglycemia: Assessment and Management
inferred← citeshttps://doi.org/10.1002/9781444324808.ch6openalex-snapshot
Islet Function and Insulin Secretion
inferred← citeshttps://doi.org/10.1002/adbi.201900291openalex-snapshot
In Vitro Platform for Studying Human Insulin Release Dynamics of Single Pancreatic Islet Microtissues at High Resolution
inferred← citeshttps://doi.org/10.1002/adfm.201200138openalex-snapshot
Ultrathin Polymeric Coatings Based on Hydrogen‐Bonded Polyphenol for Protection of Pancreatic Islet Cells
inferred← citeshttps://doi.org/10.1002/adfm.202000134openalex-snapshot
Engineered Biomaterials for Enhanced Function of Insulin‐Secreting β‐Cell Organoids
inferred← citeshttps://doi.org/10.1002/adfm.202106020openalex-snapshot
Sensing Intra‐ and Extra‐Cellular Ca2+ in the Islet of Langerhans
inferred← citeshttps://doi.org/10.1002/adfm.202315488openalex-snapshot
3D Bioprinting of Multicellular Stem Cell‐Derived Constructs to Model Pancreatic Cell Differentiation
inferred← citeshttps://doi.org/10.1002/adhm.201701111openalex-snapshot
Microphysiological Analysis Platform of Pancreatic Islet β‐Cell Spheroids
inferred← citeshttps://doi.org/10.1002/adhm.201801631openalex-snapshot
3D Bioprinting of Functional Islets of Langerhans in an Alginate/Methylcellulose Hydrogel Blend
inferred← citeshttps://doi.org/10.1002/advs.202204846openalex-snapshot
TRPC3 Regulates Islet Beta‐Cell Insulin Secretion
inferred← citeshttps://doi.org/10.1002/advs.202306128openalex-snapshot
The Sympathetic‐Immune Milieu in Metabolic Health and Diseases: Insights from Pancreas, Liver, Intestine, and Adipose Tissues
inferred← citeshttps://doi.org/10.1002/advs.202508734openalex-snapshot
Rethinking Matrigel: The Complex Journey to Matrix Alternatives in Organoid Culture
inferred← citeshttps://doi.org/10.1002/ana.23582openalex-snapshot
Glucose metabolism and pancreatic defects in spinal muscular atrophy
inferred← citeshttps://doi.org/10.1002/bdr2.2132openalex-snapshot
Tris(4‐chlorophenyl)methane and tris(4‐chlorophenyl)methanol disrupt pancreatic organogenesis and gene expression in zebrafish embryos
inferred← citeshttps://doi.org/10.1002/bip.21196openalex-snapshot
Adhesion of pancreatic beta cells to biopolymer films
inferred← citeshttps://doi.org/10.1002/bit.26442openalex-snapshot
Glucose‐stimulated insulin release: Parallel perifusion studies of free and hydrogel encapsulated human pancreatic islets
inferred← citeshttps://doi.org/10.1002/cbic.201700077openalex-snapshot
Biochemical, Cellular, Physiological, and Pathological Consequences of Human Loss of N‐Glycolylneuraminic Acid
inferred← citeshttps://doi.org/10.1002/cnm.3296openalex-snapshot
Electrophysiological models of the human pancreatic δ‐cell: From single channels to the firing of action potentials
inferred← citeshttps://doi.org/10.1002/cph4.70198openalex-snapshot
Sensing and Communicating β‐Cell Stress in the Context of T1D Etiology: New Opportunities for Therapeutic Impact
inferred← citeshttps://doi.org/10.1002/cphy.c160050openalex-snapshot
Pancreatic Blood Flow with Special Emphasis on Blood Perfusion of the Islets of Langerhans
inferred← citeshttps://doi.org/10.1002/cphy.c200026openalex-snapshot
Intercellular Communication in the Islet of Langerhans in Health and Disease
inferred← citeshttps://doi.org/10.1002/cphy.c210004openalex-snapshot
Beta‐Cell Ion Channels and Their Role in Regulating Insulin Secretion
inferred← citeshttps://doi.org/10.1002/cphy.c210031openalex-snapshot
Cell Networks in Endocrine/Neuroendocrine Gland Function
inferred← citeshttps://doi.org/10.1002/cphy.c230002openalex-snapshot
Advanced Imaging Techniques for the Characterization of Subcellular Organelle Structure in Pancreatic Islet β Cells
inferred← citeshttps://doi.org/10.1002/cphy.c230008openalex-snapshot
Pancreatic Crosstalk in the Disease Setting: Understanding the Impact of Exocrine Disease on Endocrine Function
inferred← citeshttps://doi.org/10.1002/dmrr.3609openalex-snapshot
Glucagon in type 2 diabetes: Friend or foe?
inferred← citeshttps://doi.org/10.1002/dmrr.959openalex-snapshot
Taurine supplementation enhances nutrient‐induced insulin secretion in pancreatic mice islets
inferred← citeshttps://doi.org/10.1002/dvdy.21207openalex-snapshot
Tissue surface tensions guide in vitro self‐assembly of rodent pancreatic islet cells
inferred← citeshttps://doi.org/10.1002/elps.202300095openalex-snapshot
Simultaneous LC–MS determination of glucose regulatory peptides secreted by stem cell–derived islet organoids
inferred← citeshttps://doi.org/10.1002/gepi.22494openalex-snapshot
Deconvolution analysis of cell‐type expression from bulk tissues by integrating with single‐cell expression reference
inferred← citeshttps://doi.org/10.1002/iub.1391openalex-snapshot
Biphasic decline of β‐cell function with age in euglycemic nonobese diabetic mice parallels diabetes onset
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2019.tb00068.xopenalex-snapshot
Pancreatic Blood Flow with Special Emphasis on Blood Perfusion of the Islets of Langerhans
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2021.tb00177.xopenalex-snapshot
Intercellular Communication in the Islet of Langerhans in Health and Disease
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2021.tb00189.xopenalex-snapshot
Beta‐Cell Ion Channels and Their Role in Regulating Insulin Secretion
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2022.tb00216.xopenalex-snapshot
Cell Networks in Endocrine/Neuroendocrine Gland Function
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2024.tb00288.xopenalex-snapshot
Advanced Imaging Techniques for the Characterization of Subcellular Organelle Structure in Pancreatic Islet β Cells
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2024.tb00294.xopenalex-snapshot
Pancreatic Crosstalk in the Disease Setting: Understanding the Impact of Exocrine Disease on Endocrine Function
inferred← citeshttps://doi.org/10.1002/jbio.202100257openalex-snapshot
Stimulatory responses in α‐ and β‐cells by near‐infrared (810 nm) photobiomodulation
inferred← citeshttps://doi.org/10.1002/jcp.25176openalex-snapshot
Neurotransmitters and Neuropeptides: New Players in the Control of Islet of Langerhans' Cell Mass and Function
inferred← citeshttps://doi.org/10.1002/jemt.22773openalex-snapshot
Secretory glands and microvascular systems imaged in aqueous solution by atmospheric scanning electron microscopy (ASEM)
inferred← citeshttps://doi.org/10.1002/jmor.20775openalex-snapshot
Ultrastructure of endocrine pancreatic granules during pancreatic differentiation in the grass snake, Natrix natrix L. (Lepidosauria, Serpentes)
inferred← citeshttps://doi.org/10.1002/jum.16712openalex-snapshot
Mechanosensitive Channels Mediate Pancreatic β Cells Reactive Oxygen Species Formation and Downregulation of Essential Genes During Therapeutic Ultrasound Treatment
inferred← citeshttps://doi.org/10.1002/mco2.70359openalex-snapshot
Pancreatic Islet Cell Hormones: Secretion, Function, and Diabetes Therapy
inferred← citeshttps://doi.org/10.1002/pmic.201300376openalex-snapshot
Mitochondria in metabolic disease: Getting clues from proteomic studies
inferred← citeshttps://doi.org/10.1002/smll.202402526openalex-snapshot
Circulating B Cell‐Derived Small RNA Delivered by Extracellular Vesicles: A Dialogue Mechanism for Long‐Range Targeted Renal Mitochondrial Injury in Obesity
inferred← citeshttps://doi.org/10.1002/stem.3134openalex-snapshot
Optimizing beta cell function through mesenchymal stromal cell-mediated mitochondria transfer
inferred← citeshttps://doi.org/10.1007/164_2026_804openalex-snapshot
Microvasculature of the Pancreatic Islets of Langerhans in Health and Diabetes
inferred← citeshttps://doi.org/10.1007/978-0-387-69252-4_8openalex-snapshot
Development of the Endocrine and Exocrine Pancreas
inferred← citeshttps://doi.org/10.1007/978-1-0716-0385-7_17openalex-snapshot
Assessing Mouse Islet Function
inferred← citeshttps://doi.org/10.1007/978-1-0716-2525-5_6openalex-snapshot
High-Throughput Image-Guided Microprobe Mass Spectrometric Analysis of Single Cells
inferred← citeshttps://doi.org/10.1007/978-1-0716-2807-2_8openalex-snapshot
MicroRNAs in Type 2 Diabetes: Focus on MicroRNA Profiling in Islets of Langerhans
inferred← citeshttps://doi.org/10.1007/978-1-4471-4171-6_18openalex-snapshot
Human Pancreatic Progenitors: Implications for Clinical Transplantation in Diabetes
inferred← citeshttps://doi.org/10.1007/978-1-4614-1028-7_16openalex-snapshot
Reversal of Diabetes: Islet Cell Transplantation
inferred← citeshttps://doi.org/10.1007/978-1-4939-0398-6_9openalex-snapshot
Emerging Roles for A20 in Islet Biology and Pathology
inferred← citeshttps://doi.org/10.1007/978-1-4939-6386-7_10openalex-snapshot
The Implications of Maternal Obesity on Offspring Physiology and Behavior in the Nonhuman Primate
inferred← citeshttps://doi.org/10.1007/978-1-4939-9882-1_1openalex-snapshot
Sixty Years of Drug Discovery for Type 2 Diabetes: Where Are We Now?
inferred← citeshttps://doi.org/10.1007/978-1-4939-9882-1_10openalex-snapshot
Characterization of Islet Leukocyte Populations in Human and Murine Islets by Flow Cytometry
inferred← citeshttps://doi.org/10.1007/978-1-59745-448-3_5openalex-snapshot
The Incubation and Monitoring of Cell Viability in Primary Rat Islets of Langerhans and Pancreatic β-Cell Lines
inferred← citeshttps://doi.org/10.1007/978-1-59745-448-3_7openalex-snapshot
Single-Cell RT-PCR Identification of Genes Expressed by Human Islet Endocrine Cells
inferred← citeshttps://doi.org/10.1007/978-1-60327-478-4_23openalex-snapshot
Islet and Pancreas Transplantation
inferred← citeshttps://doi.org/10.1007/978-1-60761-132-5_1openalex-snapshot
The Pancreas
inferred← citeshttps://doi.org/10.1007/978-1-60761-132-5_5openalex-snapshot
Embryonic Stem Cells and Pancreatic Differentiation
inferred← citeshttps://doi.org/10.1007/978-1-60761-132-5_7openalex-snapshot
Transdifferentiation
inferred← citeshttps://doi.org/10.1007/978-1-60761-366-4_2openalex-snapshot
Islet and Pancreas Transplantation
inferred← citeshttps://doi.org/10.1007/978-1-60761-366-4_3openalex-snapshot
Cell Cycle Regulation in Human Pancreatic Beta Cells
inferred← citeshttps://doi.org/10.1007/978-1-61779-367-7_5openalex-snapshot
Functional Analysis of Human Islets of Langerhans Maintained in Culture
inferred← citeshttps://doi.org/10.1007/978-1-62703-098-4_8openalex-snapshot
Pancreatic Reprogramming
inferred← citeshttps://doi.org/10.1007/978-1-62703-676-4_4openalex-snapshot
Imaging of Insulin Exocytosis from Pancreatic Beta Cells
inferred← citeshttps://doi.org/10.1007/978-1-84628-881-4_35openalex-snapshot
Pancreas: Embryology, Anatomy, and Physiology
inferred← citeshttps://doi.org/10.1007/978-3-030-53370-0_13openalex-snapshot
Pancreatic Islets of Langerhans: Adapting Cell and Molecular Biology to Changes of Metabolism
inferred← citeshttps://doi.org/10.1007/978-3-030-78101-9_7openalex-snapshot
Differentiation of Stem Cells into Pancreatic Lineage: In vitro Cell Culture, in vivo Transplantation in Animal Models
inferred← citeshttps://doi.org/10.1007/978-3-031-20999-4_84openalex-snapshot
Islet Allotransplantation
inferred← citeshttps://doi.org/10.1007/978-3-031-62232-8_6openalex-snapshot
Pancreatic δ Cells: An Overlooked Cell in Focus
inferred← citeshttps://doi.org/10.1007/978-3-031-96019-2_21openalex-snapshot
Pancreas: Overview
inferred← citeshttps://doi.org/10.1007/978-3-032-28826-4_5openalex-snapshot
Exploring the intrinsic and extrinsic determinants of heterogeneity in a β-cell network
inferred← citeshttps://doi.org/10.1007/978-3-319-27318-1_31-1openalex-snapshot
The Endocrine Pancreas
inferred← citeshttps://doi.org/10.1007/978-3-319-31143-2_70-1openalex-snapshot
Butyrate, a Short-Chain Fatty Acid and Histone Deacetylases Inhibitor: Nutritional, Physiological, and Pharmacological Aspects in Diabetes
inferred← citeshttps://doi.org/10.1007/978-3-319-39824-2_1openalex-snapshot
Historical Background of Pancreatic Islet Isolation
inferred← citeshttps://doi.org/10.1007/978-3-319-39824-2_2openalex-snapshot
The Different Faces of the Pancreatic Islet
inferred← citeshttps://doi.org/10.1007/978-3-319-39824-2_3openalex-snapshot
Isolation of Mouse Pancreatic Islets of Langerhans
inferred← citeshttps://doi.org/10.1007/978-3-319-39824-2_4openalex-snapshot
Pancreatic Islets: Methods for Isolation and Purification of Juvenile and Adult Pig Islets
inferred← citeshttps://doi.org/10.1007/978-3-319-39824-2_5openalex-snapshot
Isolation of Pancreatic Islets from Nonhuman Primates
inferred← citeshttps://doi.org/10.1007/978-3-319-39824-2_6openalex-snapshot
Necessities for a Clinical Islet Program
inferred← citeshttps://doi.org/10.1007/978-3-319-44675-2_31openalex-snapshot
The Endocrine Pancreas
inferred← citeshttps://doi.org/10.1007/978-3-319-45307-1_1openalex-snapshot
The Pathobiology of Diabetes Mellitus
inferred← citeshttps://doi.org/10.1007/978-3-319-45307-1_2openalex-snapshot
Comparative Analysis of Islet Development
inferred← citeshttps://doi.org/10.1007/978-3-319-45307-1_3openalex-snapshot
Mathematical Modeling of Islet Generation, Degeneration and Regeneration
inferred← citeshttps://doi.org/10.1007/978-3-319-55530-0_70openalex-snapshot
Butyrate, a Short-Chain Fatty Acid and Histone Deacetylases Inhibitor: Nutritional, Physiological, and Pharmacological Aspects in Diabetes
inferred← citeshttps://doi.org/10.1007/978-3-319-55687-1_2openalex-snapshot
Stem Cell Therapy for Type-1 Diabetes Mellitus
inferred← citeshttps://doi.org/10.1007/978-3-319-61401-4_8openalex-snapshot
Imaging in Diabetes
inferred← citeshttps://doi.org/10.1007/978-3-319-70178-3_24openalex-snapshot
Sex Differences in Androgen Regulation of Metabolism in Nonhuman Primates
inferred← citeshttps://doi.org/10.1007/978-3-642-34303-2_20openalex-snapshot
Molecular Imaging Methods in Diabetes-Related Studies
inferred← citeshttps://doi.org/10.1007/978-3-7091-0715-7_25openalex-snapshot
Overview
inferred← citeshttps://doi.org/10.1007/978-4-431-75452-7_1openalex-snapshot
Architecture of Pancreatic Islets
inferred← citeshttps://doi.org/10.1007/978-90-481-3271-3_1openalex-snapshot
Microscopic Anatomy of the Human Islet of Langerhans
inferred← citeshttps://doi.org/10.1007/978-90-481-3271-3_11openalex-snapshot
Calcium Signaling in the Islets
inferred← citeshttps://doi.org/10.1007/978-90-481-3271-3_18openalex-snapshot
Molecular Pathways Underlying the Pathogenesis of Pancreatic α-Cell Dysfunction
inferred← citeshttps://doi.org/10.1007/978-94-007-6262-6_25openalex-snapshot
Co-transplantation of Islets with Mesenychymal Stem Cells Improves Islet Revascularization and Reversal of Hyperglycemia
inferred← citeshttps://doi.org/10.1007/978-94-007-6686-0_1openalex-snapshot
Microscopic Anatomy of the Human Islet of Langerhans
inferred← citeshttps://doi.org/10.1007/978-94-007-6686-0_27openalex-snapshot
Pancreatic β Cells in Metabolic Syndrome
inferred← citeshttps://doi.org/10.1007/978-94-007-6686-0_33openalex-snapshot
Mouse Islet Isolation
inferred← citeshttps://doi.org/10.1007/978-94-007-6686-0_36openalex-snapshot
Regulation of Pancreatic Islet Formation
inferred← citeshttps://doi.org/10.1007/978-94-007-6686-0_37openalex-snapshot
Physiological and Pathophysiological Control of Glucagon Secretion by Pancreatic α-Cells
inferred← citeshttps://doi.org/10.1007/978-94-007-6686-0_9openalex-snapshot
Calcium Signaling in the Islets
inferred← citeshttps://doi.org/10.1007/978-94-007-6884-0_1-2openalex-snapshot
Microscopic Anatomy of the Human Islet of Langerhans
inferred← citeshttps://doi.org/10.1007/978-94-007-6884-0_27-2openalex-snapshot
Pancreatic Beta Cells in Metabolic Syndrome
inferred← citeshttps://doi.org/10.1007/978-94-007-6884-0_33-2openalex-snapshot
Mouse Islet Isolation
inferred← citeshttps://doi.org/10.1007/978-94-007-6884-0_36-2openalex-snapshot
Regulation of Pancreatic Islet Formation
inferred← citeshttps://doi.org/10.1007/978-94-007-6884-0_37-2openalex-snapshot
Physiological and Pathophysiological Control of Glucagon Secretion by Pancreatic α-Cells
inferred← citeshttps://doi.org/10.1007/978-94-007-6884-0_9-2openalex-snapshot
Calcium Signaling in the Islets
inferred← citeshttps://doi.org/10.1007/978-981-15-4494-1_16openalex-snapshot
Single Cell RNA Sequencing in Human Disease: Renal, Pancreatic, and Viral Diseases
inferred← citeshttps://doi.org/10.1007/978-981-16-5123-6_1openalex-snapshot
Glucose Metabolism
inferred← citeshttps://doi.org/10.1007/978-981-32-9393-9_14openalex-snapshot
Exosomes: Mediators and Therapeutic Targets of Diabetes and Pancreatic Cancer
inferred← citeshttps://doi.org/10.1007/s00005-013-0266-6openalex-snapshot
Nicotinic Cholinergic Signaling in Adipose Tissue and Pancreatic Islets Biology: Revisited Function and Therapeutic Perspectives
inferred← citeshttps://doi.org/10.1007/s00018-013-1510-2openalex-snapshot
Transcriptional control of mammalian pancreas organogenesis
inferred← citeshttps://doi.org/10.1007/s00018-014-1755-4openalex-snapshot
Beta cell connectivity in pancreatic islets: a type 2 diabetes target?
inferred← citeshttps://doi.org/10.1007/s00018-018-2778-zopenalex-snapshot
Defining G protein-coupled receptor peptide ligand expressomes and signalomes in human and mouse islets
inferred← citeshttps://doi.org/10.1007/s00018-019-03433-6openalex-snapshot
The cannabinoid ligands SR141716A and AM251 enhance human and mouse islet function via GPR55-independent signalling
inferred← citeshttps://doi.org/10.1007/s00018-023-04815-7openalex-snapshot
Pancreatic β-cell heterogeneity in adult human islets and stem cell-derived islets
inferred← citeshttps://doi.org/10.1007/s00125-006-0411-4openalex-snapshot
Comment on: Meier JJ, Lin JC, Butler AE, Galasso R, Martinez DS, Butler PC (2006) Direct evidence of attempted beta cell regeneration in an 89-year-old patient with recent-onset type 1 diabetes. Diabetologia 49:1838–1844
inferred← citeshttps://doi.org/10.1007/s00125-007-0909-4openalex-snapshot
Expanding human beta cells
inferred← citeshttps://doi.org/10.1007/s00125-008-0997-9openalex-snapshot
Blood vessels of human islets of Langerhans are surrounded by a double basement membrane
inferred← citeshttps://doi.org/10.1007/s00125-008-1103-zopenalex-snapshot
Insulin secretion from human beta cells is heterogeneous and dependent on cell-to-cell contacts
inferred← citeshttps://doi.org/10.1007/s00125-008-1238-yopenalex-snapshot
Ghrelin-producing epsilon cells in the developing and adult human pancreas
inferred← citeshttps://doi.org/10.1007/s00125-009-1382-zopenalex-snapshot
Somatostatin release, electrical activity, membrane currents and exocytosis in human pancreatic delta cells
inferred← citeshttps://doi.org/10.1007/s00125-010-1919-1openalex-snapshot
Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD–severe combined immunodeficiency (SCID) mice
inferred← citeshttps://doi.org/10.1007/s00125-011-2118-4openalex-snapshot
Pancreatic alpha cell mass in European subjects with type 2 diabetes
inferred← citeshttps://doi.org/10.1007/s00125-011-2181-xopenalex-snapshot
Stromal cell-derived factor-1 (SDF-1)/chemokine (C-X-C motif) receptor 4 (CXCR4) axis activation induces intra-islet glucagon-like peptide-1 (GLP-1) production and enhances beta cell survival
inferred← citeshttps://doi.org/10.1007/s00125-011-2369-0openalex-snapshot
Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets
inferred← citeshttps://doi.org/10.1007/s00125-012-2546-9openalex-snapshot
Delta cell secretory responses to insulin secretagogues are not mediated indirectly by insulin
inferred← citeshttps://doi.org/10.1007/s00125-012-2699-6openalex-snapshot
3-D imaging and illustration of the perfusive mouse islet sympathetic innervation and its remodelling in injury
inferred← citeshttps://doi.org/10.1007/s00125-013-3073-zopenalex-snapshot
Glucose-stimulated insulin secretion: the hierarchy of its multiple cellular and subcellular mechanisms
inferred← citeshttps://doi.org/10.1007/s00125-013-3116-5openalex-snapshot
Association of proinflammatory cytokines and islet resident leucocytes with islet dysfunction in type 2 diabetes
inferred← citeshttps://doi.org/10.1007/s00125-014-3252-6openalex-snapshot
Insulin secretion from beta cells in intact mouse islets is targeted towards the vasculature
inferred← citeshttps://doi.org/10.1007/s00125-014-3266-0openalex-snapshot
Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+ in pancreatic beta cells
inferred← citeshttps://doi.org/10.1007/s00125-014-3418-2openalex-snapshot
The dark side of islet vasculature
inferred← citeshttps://doi.org/10.1007/s00125-015-3598-4openalex-snapshot
Human islet function following 20 years of cryogenic biobanking
inferred← citeshttps://doi.org/10.1007/s00125-015-3625-5openalex-snapshot
Delta cell death in the islet of Langerhans and the progression from normal glucose tolerance to type 2 diabetes in non-human primates (baboon, Papio hamadryas)
inferred← citeshttps://doi.org/10.1007/s00125-015-3699-0openalex-snapshot
New insights into the architecture of the islet of Langerhans: a focused cross-species assessment
inferred← citeshttps://doi.org/10.1007/s00125-015-3747-9openalex-snapshot
Spatial and temporal coordination of insulin granule exocytosis in intact human pancreatic islets
inferred← citeshttps://doi.org/10.1007/s00125-017-4409-xopenalex-snapshot
Human pancreatic neuro-insular network in health and fatty infiltration
inferred← citeshttps://doi.org/10.1007/s00125-018-4743-7openalex-snapshot
Disruption of beta cell acetyl-CoA carboxylase-1 in mice impairs insulin secretion and beta cell mass
inferred← citeshttps://doi.org/10.1007/s00125-018-4772-2openalex-snapshot
Use of human islets to understand islet biology and diabetes: progress, challenges and suggestions
inferred← citeshttps://doi.org/10.1007/s00125-020-05196-3openalex-snapshot
Alpha cell regulation of beta cell function
inferred← citeshttps://doi.org/10.1007/s00125-020-05288-0openalex-snapshot
Paracrine regulation of somatostatin secretion by insulin and glucagon in mouse pancreatic islets
inferred← citeshttps://doi.org/10.1007/s00125-020-05345-8openalex-snapshot
Structural and functional polarisation of human pancreatic beta cells in islets from organ donors with and without type 2 diabetes
inferred← citeshttps://doi.org/10.1007/s00125-020-05346-7openalex-snapshot
SUR1-mutant iPS cell-derived islets recapitulate the pathophysiology of congenital hyperinsulinism
inferred← citeshttps://doi.org/10.1007/s00125-021-05504-5openalex-snapshot
Local islet remodelling associated with duct lesion–islet complex in adult human pancreas
inferred← citeshttps://doi.org/10.1007/s00125-021-05563-8openalex-snapshot
Immunoregulated insulitis and slow-progressing type 1 diabetes after duodenopancreatectomy
inferred← citeshttps://doi.org/10.1007/s00125-023-05931-6openalex-snapshot
RELA governs a network of islet-specific metabolic genes necessary for beta cell function
inferred← citeshttps://doi.org/10.1007/s00125-023-05970-zopenalex-snapshot
Islet autoimmunity in human type 1 diabetes: initiation and progression from the perspective of the beta cell
inferred← citeshttps://doi.org/10.1007/s00125-024-06341-yopenalex-snapshot
Single-cell RNA sequencing identifies endothelial-derived HBEGF as promoting pancreatic beta cell proliferation in mice via the EGFR–Kmt5a–H4K20me pathway
inferred← citeshttps://doi.org/10.1007/s00125-025-06376-9openalex-snapshot
Beyond the loss of beta cells: a quantitative analysis of islet architecture in adults with and without type 1 diabetes
inferred← citeshttps://doi.org/10.1007/s00125-025-06425-3openalex-snapshot
Proinflammatory cytokine-induced alpha cell impairment in human islet microtissues is partially restored by dual incretin receptor agonism
inferred← citeshttps://doi.org/10.1007/s00125-025-06474-8openalex-snapshot
Stem-cell-derived beta cells mature metabolically upon murine engraftment
inferred← citeshttps://doi.org/10.1007/s00125-025-06541-0openalex-snapshot
I-BET151 modulates glucokinase gene expression and beta cell function in part through changes in FOXO1 expression
inferred← citeshttps://doi.org/10.1007/s00125-026-06769-4openalex-snapshot
Somatostatin receptors shape insulin and glucagon output within the pancreatic islet in mice through direct and paracrine effects
inferred← citeshttps://doi.org/10.1007/s00125-026-06839-7openalex-snapshot
Pancreatic islets: new discoveries for innovative treatments of diabetes?
inferred← citeshttps://doi.org/10.1007/s00125-026-06884-2openalex-snapshot
BAF60A governs beta cell identity to control systemic glucose homeostasis
inferred← citeshttps://doi.org/10.1007/s00216-026-06557-4openalex-snapshot
Spatially resolved lipid compartmentalization in human pancreatic islets revealed by high-resolution ultra-low-flow-rate desorption electrospray ionization mass spectrometry imaging
inferred← citeshttps://doi.org/10.1007/s00268-006-0474-xopenalex-snapshot
Re: Postoperative Glycemic Control in Patients Undergoing Central Pancreatectomy for Mid‐gland Lesions
inferred← citeshttps://doi.org/10.1007/s00268-006-0719-8openalex-snapshot
Islet Vasculature as a Regulator of Endocrine Pancreas Function
inferred← citeshttps://doi.org/10.1007/s00418-006-0248-4openalex-snapshot
Catalase expression in pancreatic alpha cells of diabetic and non-diabetic mice
inferred← citeshttps://doi.org/10.1007/s00418-014-1292-0openalex-snapshot
Co-expression of the homologous proteases fibroblast activation protein and dipeptidyl peptidase-IV in the adult human Langerhans islets
inferred← citeshttps://doi.org/10.1007/s00424-024-03045-5openalex-snapshot
Hyperglucagonemia and glucagon hypersecretion in early type 2 diabetes result from multifaceted dysregulation of pancreatic mouse α-cells
inferred← citeshttps://doi.org/10.1007/s00435-024-00667-2openalex-snapshot
Microscopic investigation of the exocrine and endocrine pancreas in the southern white-breasted hedgehog (Erinaceus concolor)
inferred← citeshttps://doi.org/10.1007/s00441-008-0733-2openalex-snapshot
Impact of Sur1 gene inactivation on the morphology of mouse pancreatic endocrine tissue
inferred← citeshttps://doi.org/10.1007/s00441-013-1593-yopenalex-snapshot
Different ghrelin localisation in adult human and rat endocrine pancreas
inferred← citeshttps://doi.org/10.1007/s00592-021-01737-3openalex-snapshot
Felix dies natalis, insulin… ceterum autem censeo “beta is better”
inferred← citeshttps://doi.org/10.1007/s00726-015-1988-zopenalex-snapshot
Taurine supplementation ameliorates glucose homeostasis, prevents insulin and glucagon hypersecretion, and controls β, α, and δ-cell masses in genetic obese mice
inferred← citeshttps://doi.org/10.1007/s00726-018-2650-3openalex-snapshot
Regulation of glucose and lipid metabolism by the pancreatic and extra-pancreatic actions of taurine
inferred← citeshttps://doi.org/10.1007/s10441-010-9115-8openalex-snapshot
Modeling Mechanisms of Cell Secretion
inferred← citeshttps://doi.org/10.1007/s10495-016-1212-yopenalex-snapshot
Human islet cells are killed by BID-independent mechanisms in response to FAS ligand
inferred← citeshttps://doi.org/10.1007/s10517-013-2255-5openalex-snapshot
Immunohistochemical Study of α- and β-Cell Distribution in Human Pancreatic Langerhans Islets of Various Types
inferred← citeshttps://doi.org/10.1007/s10544-019-0443-4openalex-snapshot
Compact fluidic system for functional assessment of pancreatic islets
inferred← citeshttps://doi.org/10.1007/s10616-014-9690-7openalex-snapshot
Filtration is a time-efficient option to Histopaque, providing good-quality islets in mouse islet isolation
inferred← citeshttps://doi.org/10.1007/s10735-026-10901-4openalex-snapshot
Syntaxin-4, a key exocytosis mediating protein, shows heterogeneous expression in insulin-positive cells of human donors with new-onset and longer duration of type 1 diabetes: comparison with non-diabetic autoantibody-positive and -negative donors
inferred← citeshttps://doi.org/10.1007/s11892-015-0635-0openalex-snapshot
Transcriptional Regulation of the Pancreatic Islet: Implications for Islet Function
inferred← citeshttps://doi.org/10.1007/s11892-015-0655-9openalex-snapshot
Genes Affecting β-Cell Function in Type 1 Diabetes
inferred← citeshttps://doi.org/10.1007/s11892-018-1059-4openalex-snapshot
Biomarkers in Islet Cell Transplantation for Type 1 Diabetes
inferred← citeshttps://doi.org/10.1007/s11892-018-1083-4openalex-snapshot
The Effect of Age on the Progression and Severity of Type 1 Diabetes: Potential Effects on Disease Mechanisms
inferred← citeshttps://doi.org/10.1007/s11892-019-1194-6openalex-snapshot
Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes
inferred← citeshttps://doi.org/10.1007/s12015-017-9783-8openalex-snapshot
3D-Models of Insulin-Producing β-Cells: from Primary Islet Cells to Stem Cell-Derived Islets
inferred← citeshttps://doi.org/10.1007/s12015-018-9845-6openalex-snapshot
Islet-Like Structures Generated In Vitro from Adult Human Liver Stem Cells Revert Hyperglycemia in Diabetic SCID Mice
inferred← citeshttps://doi.org/10.1007/s12016-010-8220-4openalex-snapshot
Viruses and Cytotoxic T Lymphocytes in Type 1 Diabetes
inferred← citeshttps://doi.org/10.1007/s12018-014-9168-3openalex-snapshot
The Role of PTHrP in Pancreatic Beta-Cells and Implications for Diabetes Pathophysiology and Treatment
inferred← citeshttps://doi.org/10.1007/s12020-007-0004-0openalex-snapshot
Islet α-cells do not influence insulin secretion from β-cells through cell–cell contact
inferred← citeshttps://doi.org/10.1007/s12020-013-0032-xopenalex-snapshot
Zinc and insulin in pancreatic beta-cells
inferred← citeshttps://doi.org/10.1007/s12020-014-0212-3openalex-snapshot
Episodic hormone secretion: a comparison of the basis of pulsatile secretion of insulin and GnRH
inferred← citeshttps://doi.org/10.1007/s12020-015-0534-9openalex-snapshot
Beta-cell destruction and preservation in childhood and adult onset type 1 diabetes
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