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West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H

https://doi.org/10.1073/pnas.0605668103
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jmv.10261openalex-snapshot
Antibodies from dengue patient sera cross‐react with endothelial cells and induce damage
inferredcites →https://doi.org/10.1006/viro.1996.0307openalex-snapshot
Immunolocalization of the Dengue Virus Nonstructural Glycoprotein NS1 Suggests a Role in Viral RNA Replication
inferredcites →https://doi.org/10.1006/viro.1996.0406openalex-snapshot
Mutagenesis of the N-Linked Glycosylation Sites of the Yellow Fever Virus NS1 Protein: Effects on Virus Replication and Mouse Neurovirulence
inferredcites →https://doi.org/10.1006/viro.1998.9205openalex-snapshot
Mechanisms of Resistance of HIV-1 Primary Isolates to Complement-Mediated Lysis
inferredcites →https://doi.org/10.1007/978-3-662-04700-2_4openalex-snapshot
The Role of Complement in Innate and Adaptive Immunity
inferredcites →https://doi.org/10.1007/s007050050127openalex-snapshot
The dengue virus nonstructural-1 protein (NS1) generatesantibodies to common epitopes on human blood clotting,integrin/adhesin proteins and binds to humanendothelial cells: potential implications in haemorrhagic fever pathogenesis
inferredcites →https://doi.org/10.1016/0042-6822(88)90408-4openalex-snapshot
Evidence that the mature form of the flavivirus nonstructural protein NS1 is a dimer
inferredcites →https://doi.org/10.1016/0042-6822(89)90161-xopenalex-snapshot
Maturation of Japanese encephalitis virus glycoproteins produced by infected mammalian and mosquito cells
inferredcites →https://doi.org/10.1016/0042-6822(89)90544-8openalex-snapshot
Newly synthesized dengue-2 virus nonstructural protein NS1 is a soluble protein but becomes partially hydrophobic and membrane-associated after dimerization
inferredcites →https://doi.org/10.1016/j.molimm.2005.06.016openalex-snapshot
Complement escape of human pathogenic bacteria by acquisition of complement regulators
inferredcites →https://doi.org/10.1016/s0161-5890(03)00108-1openalex-snapshot
Complement resistance mechanisms of streptococci
inferredcites →https://doi.org/10.1016/s0161-5890(99)00038-3openalex-snapshot
Factor H and disease: a complement regulator affects vital body functions
inferredcites →https://doi.org/10.1016/s0167-5699(00)01754-0openalex-snapshot
Natural antibodies and complement link innate and acquired immunity
inferredcites →https://doi.org/10.1016/s1074-7613(02)00338-2openalex-snapshot
Autoreactive CD8 T Cells in Organ-Specific Autoimmunity
inferredcites →https://doi.org/10.1016/s1074-7613(02)00369-2openalex-snapshot
Critical Role of Complement and Viral Evasion of Complement in Acute, Persistent, and Latent γ-Herpesvirus Infection
inferredcites →https://doi.org/10.1021/ac026136sopenalex-snapshot
Fast-Response Proteomics by Accelerated In-Gel Digestion of Proteins
inferredcites →https://doi.org/10.1038/nm0402-373openalex-snapshot
Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection
inferredcites →https://doi.org/10.1038/nm1240openalex-snapshot
Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus
inferredcites →https://doi.org/10.1042/bst0300971openalex-snapshot
Factor H family proteins: on complement, microbes and human diseases
inferredcites →https://doi.org/10.1056/nejm197311082891902openalex-snapshot
The Potential Pathogenic Role of Complement in Dengue Hemorrhagic Shock Syndrome
inferredcites →https://doi.org/10.1056/nejm200104053441406openalex-snapshot
Complement
inferredcites →https://doi.org/10.1056/nejm200104123441506openalex-snapshot
Complement
inferredcites →https://doi.org/10.1073/pnas.0402353101openalex-snapshot
A proteomic approach for the discovery of protease substrates
inferredcites →https://doi.org/10.1073/pnas.82.5.1490openalex-snapshot
gp140, the C3d receptor of human B lymphocytes, is also the Epstein-Barr virus receptor.
inferredcites →https://doi.org/10.1073/pnas.85.5.1657openalex-snapshot
Antiphagocytic activity of streptococcal M protein: selective binding of complement control protein factor H.
inferredcites →https://doi.org/10.1073/pnas.96.22.12708openalex-snapshot
Humoral response to herpes simplex virus is complement-dependent
inferredcites →https://doi.org/10.1074/jbc.m004650200openalex-snapshot
Dissecting Sites Important for Complement Regulatory Activity in Membrane Cofactor Protein (MCP; CD46)
inferredcites →https://doi.org/10.1084/jem.146.1.257openalex-snapshot
Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution.
inferredcites →https://doi.org/10.1084/jem.182.2.501openalex-snapshot
Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1.
inferredcites →https://doi.org/10.1084/jem.188.4.671openalex-snapshot
Binding of Complement Factor H to Loop 5 of Porin Protein 1A: A Molecular Mechanism of Serum Resistance of Nonsialylated Neisseria gonorrhoeae
inferredcites →https://doi.org/10.1084/jem.190.8.1165openalex-snapshot
Protective T Cell–Independent Antiviral Antibody Responses Are Dependent on Complement
inferredcites →https://doi.org/10.1084/jem.20052388openalex-snapshot
Protective immune responses against West Nile virus are primed by distinct complement activation pathways
inferredcites →https://doi.org/10.1086/342600openalex-snapshot
Facilitation of Cell Adhesion by Immobilized Dengue Viral Nonstructural Protein 1 (NS1): Arginine‐Glycine‐Aspartic Acid Structural Mimicry within the Dengue Viral NS1 Antigen
inferredcites →https://doi.org/10.1086/343813openalex-snapshot
High Circulating Levels of the Dengue Virus Nonstructural Protein NS1 Early in Dengue Illness Correlate with the Development of Dengue Hemorrhagic Fever
inferredcites →https://doi.org/10.1086/500949openalex-snapshot
Vascular Leakage in Severe Dengue Virus Infections: A Potential Role for the Nonstructural Viral Protein NS1 and Complement
inferredcites →https://doi.org/10.1099/0022-1317-72-4-961openalex-snapshot
Production of dimer-specific and dengue virus group cross-reactive mouse monoclonal antibodies to the dengue 2 virus non-structural glycoprotein NS1
inferredcites →https://doi.org/10.1128/iai.30.3.899-901.1980openalex-snapshot
Role of complement in viral infections: participation of terminal complement components (C5 to C9) in recovery of mice from Sindbis virus infection
inferredcites →https://doi.org/10.1128/iai.61.8.3129-3136.1993openalex-snapshot
Role of the YadA protein in prevention of opsonization of Yersinia enterocolitica by C3b molecules
inferredcites →https://doi.org/10.1128/jcm.38.3.1053-1057.2000openalex-snapshot
An Antigen Capture Enzyme-Linked Immunosorbent Assay Reveals High Levels of the Dengue Virus Protein NS1 in the Sera of Infected Patients
inferredcites →https://doi.org/10.1128/jcm.40.02.376-381.2002openalex-snapshot
Enzyme-Linked Immunosorbent Assay Specific to Dengue Virus Type 1 Nonstructural Protein NS1 Reveals Circulation of the Antigen in the Blood during the Acute Phase of Disease in Patients Experiencing Primary or Secondary Infections
inferredcites →https://doi.org/10.1128/jvi.71.12.9608-9617.1997openalex-snapshot
trans-Complementation of yellow fever virus NS1 reveals a role in early RNA replication
inferredcites →https://doi.org/10.1128/jvi.73.12.10272-10280.1999openalex-snapshot
Efficient trans -Complementation of the Flavivirus Kunjin NS5 Protein but Not of the NS1 Protein Requires Its Coexpression with Other Components of the Viral Replicase
inferredcites →https://doi.org/10.1128/jvi.79.12.7466-7477.2005openalex-snapshot
Complement Activation Is Required for Induction of a Protective Antibody Response against West Nile Virus Infection
inferredcites →https://doi.org/10.1128/jvi.79.17.11403-11411.2005openalex-snapshot
The Secreted Form of Dengue Virus Nonstructural Protein NS1 Is Endocytosed by Hepatocytes and Accumulates in Late Endosomes: Implications for Viral Infectivity
inferredcites →https://doi.org/10.1128/jvi.79.22.13924-13933.2005openalex-snapshot
NS1 Protein Secretion during the Acute Phase of West Nile Virus Infection
inferredcites →https://doi.org/10.1128/jvi.80.3.1340-1351.2006openalex-snapshot
Antibodies against West Nile Virus Nonstructural Protein NS1 Prevent Lethal Infection through Fc γ Receptor-Dependent and -Independent Mechanisms
inferredcites →https://doi.org/10.1186/1743-422x-2-53openalex-snapshot
Actively replicating West Nile virus is resistant to cytoplasmic delivery of siRNA
inferredcites →https://doi.org/10.4049/jimmunol.105.6.1565openalex-snapshot
Partial Purification and Characterization of a Dengue Virus Soluble Complement-Fixing Antigen
inferredcites →https://doi.org/10.4049/jimmunol.121.4.1437openalex-snapshot
The Importance of an Intact Complement Pathway in Recovery from a Primary Viral Infection: Influenza in Decomplemented and in C5-Deficient Mice
inferredcites →https://doi.org/10.4049/jimmunol.156.11.4415openalex-snapshot
Membrane cofactor protein (MCP; CD46). Isoforms differ in protection against the classical pathway of complement
inferredcites →https://doi.org/10.4049/jimmunol.167.5.2446openalex-snapshot
Cutting Edge: Myeloid Complement C3 Enhances the Humoral Response To Peripheral Viral Infection
inferredcites →https://doi.org/10.4049/jimmunol.168.12.6298openalex-snapshot
Role of Membrane Cofactor Protein (CD46) in Regulation of C4b and C3b Deposited on Cells
inferredcites →https://doi.org/10.4049/jimmunol.169.2.657openalex-snapshot
Endothelial Cell Apoptosis Induced by Antibodies Against Dengue Virus Nonstructural Protein 1 Via Production of Nitric Oxide
inferredcites →https://doi.org/10.4049/jimmunol.172.10.6195openalex-snapshot
Lysine-Dependent Multipoint Binding of the Borrelia burgdorferi Virulence Factor Outer Surface Protein E to the C Terminus of Factor H
inferredcites →https://doi.org/10.4049/jimmunol.174.1.395openalex-snapshot
Expression of Cytokine, Chemokine, and Adhesion Molecules during Endothelial Cell Activation Induced by Antibodies against Dengue Virus Nonstructural Protein 1

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Recombination and positive selection identified in complete genome sequences of Japanese encephalitis virus
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Bovine viral diarrhea virus structural protein E2 as a complement regulatory protein
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Inhibition of Viruses
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Intrinsically disordered proteins of viruses: Involvement in the mechanism of cell regulation and pathogenesis
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The flavivirus NS1 protein: Molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker
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CCP domain containing protein from complement factor H of Paralichthys olivaceus has potential effects against Edwardsiella piscicida infection
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Secreted complement regulatory protein clusterin interacts with dengue virus nonstructural protein 1
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Pathogenesis of Flavivirus Infections: Using and Abusing the Host Cell
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Yellow Fever: A Reemerging Threat
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Flavivirus NS1 as a pivotal virulence factor and a tractable target for next-generation antivirals, vaccines, and immunodiagnostics
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A cDNA Clone-Launched Platform for High-Yield Production of Inactivated Zika Vaccine
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Potential targets for therapeutic intervention and structure based vaccine design against Zika virus
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Complement factor H gene (CFH) polymorphisms C-257T, G257A and haplotypes are associated with protection against severe dengue phenotype, possible related with high CFH expression
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Utilizing complement evasion strategies to design complement-based antibacterial immunotherapeutics: Lessons from the pathogenic Neisseriae
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The grand escape – how pathogens outsmart the human complement system
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Dengue nonstructural protein-1 status is not associated to circulating levels of interleukin-17, C-reactive protein and complement in children with acute dengue
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Novel short peptide tag from a bacterial toxin for versatile applications
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Flaviviruses are neurotropic, but how do they invade the CNS?
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A specific and sensitive antigen capture assay for NS1 protein quantitation in Japanese encephalitis virus infection
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NS1-based DNA vaccination confers mouse protective immunity against ZIKV challenge
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A potential bimodal interplay between heme and complement factor H 402H in the deregulation of the complement alternative pathway by SARS-CoV-2
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Complement evasion of pathogens: Common strategies are shared by diverse organisms
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Immune evasion by acquisition of complement inhibitors: The mould Aspergillus binds both factor H and C4b binding protein
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Evaluating the clinical utility of measuring levels of factor H and the related proteins
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Novel approaches for the rapid development of rationally designed arbovirus vaccines
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Antibodies generated by immunization with the NS1 protein of West Nile virus confer partial protection against lethal Japanese encephalitis virus challenge
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Complement modulates pathogenesis and antibody-dependent neutralization of West Nile virus infection through a C5-independent mechanism
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Direct random insertion of an influenza virus immunologic determinant into the NS1 glycoprotein of a vaccine flavivirus
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Nonstructural NS1 proteins of several mosquito-borne Flavivirus do not inhibit TLR3 signaling
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Complement and viral pathogenesis
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N-linked glycosylation of dengue virus NS1 protein modulates secretion, cell-surface expression, hexamer stability, and interactions with human complement
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Abrogation of TLR3 inhibition by discrete amino acid changes in the C-terminal half of the West Nile virus NS1 protein
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Modulation of innate immune signaling by the secreted form of the West Nile virus NS1 glycoprotein
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Parainfluenza virus 5 upregulates CD55 expression to produce virions with enhanced resistance to complement-mediated neutralization
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Modulation of innate immune responses by virus-host interactions in Orthoflavivirus
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Recent advances in understanding the adaptive immune response to Zika virus and the effect of previous flavivirus exposure
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Roles of NS1 Protein in Flavivirus Pathogenesis
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Drug Discovery of Antiviral Inhibitors Targeting Dengue Virus NS4B Protein
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Structural Disorder in Viral Proteins
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West Nile virus infection and immunity
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Zika virus NS1 structure reveals diversity of electrostatic surfaces among flaviviruses
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Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy
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A replication-defective Japanese encephalitis virus (JEV) vaccine candidate with NS1 deletion confers dual protection against JEV and West Nile virus in mice
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Experimental Adaptation of the Yellow Fever Virus to the Mosquito Aedes albopictus and Potential risk of urban epidemics in Brazil, South America
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Development of a quantitative NS1 antigen enzyme-linked immunosorbent assay (ELISA) for Zika virus detection using a novel virus-specific mAb
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The interaction of GRP78 and Zika virus E and NS1 proteins occurs in a chaperone-client manner
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Kinetics of NS1 and anti-NS1 IgG following dengue infection reveals likely early formation of immune complexes in secondary infected patients
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SARS-CoV-2 nucleocapsid protein forms complexes with soluble complement regulatory proteins that can bind to the virion
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A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro
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Phenotypic Screening to Discover Inhibitors of Dengue Virus
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Multi-scale computational insights into West Nile virus E-protein adsorption on graphene and phosphorene nanomaterials
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Flavivirus nonstructural protein NS1: Complementary surprises
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Secreted dengue virus nonstructural protein NS1 is an atypical barrel-shaped high-density lipoprotein
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Structural basis of Flavivirus NS1 assembly and antibody recognition
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Glycan recognition by collectin-11 drives SARS-CoV-2 infectivity and membrane injury of respiratory epithelial cells
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Oligomeric viral proteins: small in size, large in presence
inferred← citeshttps://doi.org/10.1080/17460441.2020.1714586openalex-snapshot
New avenues for therapeutic discovery against West Nile virus
inferred← citeshttps://doi.org/10.1080/22221751.2024.2417868openalex-snapshot
SARS-CoV-2 hijacks host CD55, CD59 and factor H to impair antibody-dependent complement-mediated lysis
inferred← citeshttps://doi.org/10.1084/jem.20092545openalex-snapshot
Antagonism of the complement component C4 by flavivirus nonstructural protein NS1
inferred← citeshttps://doi.org/10.1089/jir.2009.0069openalex-snapshot
Mechanisms of Evasion of the Type I Interferon Antiviral Response by Flaviviruses
inferred← citeshttps://doi.org/10.1089/vim.2007.0061openalex-snapshot
Role of Complement in Immune Regulation and Its Exploitation by Virus
inferred← citeshttps://doi.org/10.1089/vim.2012.0102openalex-snapshot
Serotype-Specific Anti-Dengue Virus NS1 Mouse Antibodies Cross-React with prM and Are Potentially Involved in Virus Production
inferred← citeshttps://doi.org/10.1089/vim.2017.0046openalex-snapshot
Zika Virus: Immune Evasion Mechanisms, Currently Available Therapeutic Regimens, and Vaccines
inferred← citeshttps://doi.org/10.1089/vim.2019.0082openalex-snapshot
Immune Evasion Strategies Used by Zika Virus to Infect the Fetal Eye and Brain
inferred← citeshttps://doi.org/10.1093/infdis/jiad122openalex-snapshot
Soluble NS1 Antagonizes IgG- and IgA- Mediated Monocytic Phagocytosis of DENV Infected Cells
inferred← citeshttps://doi.org/10.1097/qco.0b013e32811ebfb0openalex-snapshot
Adverse events following immunization: perception and evidence
inferred← citeshttps://doi.org/10.1099/jgv.0.001547openalex-snapshot
Changes in complement alternative pathway components, factor B and factor H during dengue virus infection in the AG129 mouse
inferred← citeshttps://doi.org/10.1099/vir.0.000053openalex-snapshot
Last 20 aa of the West Nile virus NS1′ protein are responsible for its retention in cells and the formation of unique heat-stable dimers
inferred← citeshttps://doi.org/10.1099/vir.0.030460-0openalex-snapshot
The vaccinia virus A56 protein: a multifunctional transmembrane glycoprotein that anchors two secreted viral proteins
inferred← citeshttps://doi.org/10.1099/vir.0.033159-0openalex-snapshot
Structural gene (prME) chimeras of St Louis encephalitis virus and West Nile virus exhibit altered in vitro cytopathic and growth phenotypes
inferred← citeshttps://doi.org/10.1099/vir.0.034900-0openalex-snapshot
Comprehensive mapping of West Nile virus (WNV)- and Japanese encephalitis virus serocomplex-specific linear B-cell epitopes from WNV non-structural protein 1
inferred← citeshttps://doi.org/10.1099/vir.0.036640-0openalex-snapshot
A cross-protective mAb recognizes a novel epitope within the flavivirus NS1 protein
inferred← citeshttps://doi.org/10.1099/vir.0.039321-0openalex-snapshot
Structure of the dengue virus glycoprotein non-structural protein 1 by electron microscopy and single-particle analysis
inferred← citeshttps://doi.org/10.1099/vir.0.057968-0openalex-snapshot
NS1′ protein expression facilitates production of Japanese encephalitis virus in avian cells and embryonated chicken eggs
inferred← citeshttps://doi.org/10.1101/2023.09.15.557969openalex-snapshot
Mapping the interaction sites of Influenza A viruses and human complement Factor H
inferred← citeshttps://doi.org/10.1101/2023.12.11.571109openalex-snapshot
The complement pattern recognition molecule CL-11 promotes invasion and injury of respiratory epithelial cells by SARS-CoV-2
inferred← citeshttps://doi.org/10.1101/2025.11.19.689067openalex-snapshot
Dengue Virus NS1 Binds Ephrin B1 to Trigger Endothelial Dysfunction
inferred← citeshttps://doi.org/10.1111/cei.12184openalex-snapshot
Complement alternative pathway genetic variation and Dengue infection in the Thai population
inferred← citeshttps://doi.org/10.1126/science.1247749openalex-snapshot
Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System
inferred← citeshttps://doi.org/10.1126/science.1251249openalex-snapshot
Unraveling a Flavivirus Enigma
inferred← citeshttps://doi.org/10.1128/cmr.00045-12openalex-snapshot
West Nile Virus: Biology, Transmission, and Human Infection
inferred← citeshttps://doi.org/10.1128/cvi.00070-07openalex-snapshot
Complex Adenovirus-Mediated Expression of West Nile Virus C, PreM, E, and NS1 Proteins Induces both Humoral and Cellular Immune Responses
inferred← citeshttps://doi.org/10.1128/iai.01037-07openalex-snapshot
The Opportunistic Human Pathogenic FungusAspergillus fumigatusEvades the Host Complement System
inferred← citeshttps://doi.org/10.1128/jvi.00157-12openalex-snapshot
Evidence for a Genetic and Physical Interaction between Nonstructural Proteins NS1 and NS4B That Modulates Replication of West Nile Virus
inferred← citeshttps://doi.org/10.1128/jvi.00193-11openalex-snapshot
Interactions of Human Complement with Virus Particles Containing the Nipah Virus Glycoproteins
inferred← citeshttps://doi.org/10.1128/jvi.00226-08openalex-snapshot
West Nile Virus Nonstructural Protein 1 Inhibits TLR3 Signal Transduction
inferred← citeshttps://doi.org/10.1128/jvi.00372-10openalex-snapshot
Poxvirus Complement Control Proteins Are Expressed on the Cell Surface through an Intermolecular Disulfide Bridge with the Viral A56 Protein
inferred← citeshttps://doi.org/10.1128/jvi.00375-12openalex-snapshot
Trafficking and Replication Patterns Reveal Splenic Macrophages as Major Targets of Dengue Virus in Mice
inferred← citeshttps://doi.org/10.1128/jvi.00661-22openalex-snapshot
Molecular Determinants of Tissue Specificity of Flavivirus Nonstructural Protein 1 Interaction with Endothelial Cells
inferred← citeshttps://doi.org/10.1128/jvi.00713-09openalex-snapshot
The Paramyxoviruses Simian Virus 5 and Mumps Virus Recruit Host Cell CD46 To Evade Complement-Mediated Neutralization
inferred← citeshttps://doi.org/10.1128/jvi.00775-10openalex-snapshot
A Short N-Terminal Peptide Motif on Flavivirus Nonstructural Protein NS1 Modulates Cellular Targeting and Immune Recognition
inferred← citeshttps://doi.org/10.1128/jvi.00844-21openalex-snapshot
Levels of Circulating NS1 Impact West Nile Virus Spread to the Brain
inferred← citeshttps://doi.org/10.1128/jvi.00849-11openalex-snapshot
Immunization with a Vaccine Combining Herpes Simplex Virus 2 (HSV-2) Glycoprotein C (gC) and gD Subunits Improves the Protection of Dorsal Root Ganglia in Mice and Reduces the Frequency of Recurrent Vaginal Shedding of HSV-2 DNA in Guinea Pigs Compared to Immunization with gD Alone
inferred← citeshttps://doi.org/10.1128/jvi.00886-12openalex-snapshot
Incorporation of Host Complement Regulatory Proteins into Newcastle Disease Virus Enhances Complement Evasion
inferred← citeshttps://doi.org/10.1128/jvi.00912-16openalex-snapshot
Inhibition of the Membrane Attack Complex by Dengue Virus NS1 through Interaction with Vitronectin and Terminal Complement Proteins
inferred← citeshttps://doi.org/10.1128/jvi.01101-13openalex-snapshot
NS1′ Colocalizes with NS1 and Can Substitute for NS1 in West Nile Virus Replication
inferred← citeshttps://doi.org/10.1128/jvi.01342-15openalex-snapshot
Dengue Virus NS1 Protein Modulates Cellular Energy Metabolism by Increasing Glyceraldehyde-3-Phosphate Dehydrogenase Activity
inferred← citeshttps://doi.org/10.1128/jvi.01847-07openalex-snapshot
Human Astrovirus Coat Protein Inhibits Serum Complement Activation via C1, the First Component of the Classical Pathway
inferred← citeshttps://doi.org/10.1128/jvi.01850-08openalex-snapshot
Virus-Specific Cytolytic Antibodies to Nonstructural Protein 1 of Japanese Encephalitis Virus Effect Reduction of Virus Output from Infected Cells
inferred← citeshttps://doi.org/10.1128/jvi.01868-17openalex-snapshot
Structural Study of the C-Terminal Domain of Nonstructural Protein 1 from Japanese Encephalitis Virus
inferred← citeshttps://doi.org/10.1128/jvi.01990-07openalex-snapshot
Complement Is an Essential Component of the Immune Response to Adeno-Associated Virus Vectors
inferred← citeshttps://doi.org/10.1128/jvi.02062-19openalex-snapshot
A Factor I-Like Activity Associated with Chikungunya Virus Contributes to Its Resistance to the Human Complement System
inferred← citeshttps://doi.org/10.1128/jvi.02141-25openalex-snapshot
Impact of cellular proteases on the function of antiviral antibodies
inferred← citeshttps://doi.org/10.1128/jvi.02396-16openalex-snapshot
West Nile Virus NS1 Antagonizes Interferon Beta Production by Targeting RIG-I and MDA5
inferred← citeshttps://doi.org/10.1128/jvi.02426-07openalex-snapshot
Cell Surface Expression of the Vaccinia Virus Complement Control Protein Is Mediated by Interaction with the Viral A56 Protein and Protects Infected Cells from Complement Attack
inferred← citeshttps://doi.org/10.1128/jvi.02427-14openalex-snapshot
A Novel Factor I Activity in Nipah Virus Inhibits Human Complement Pathways through Cleavage of C3b
inferred← citeshttps://doi.org/10.1128/jvi.02449-10openalex-snapshot
Transcriptional Repression of C4 Complement by Hepatitis C Virus Proteins
inferred← citeshttps://doi.org/10.1128/jvi.02510-10openalex-snapshot
Inhibition of Dengue Virus through Suppression of Host Pyrimidine Biosynthesis
inferred← citeshttps://doi.org/10.1128/mbio.02440-21openalex-snapshot
Human Monoclonal Antibodies against NS1 Protein Protect against Lethal West Nile Virus Infection
inferred← citeshttps://doi.org/10.1128/mbio.02861-18openalex-snapshot
Antibodies Elicited by an NS1-Based Vaccine Protect Mice against Zika Virus
inferred← citeshttps://doi.org/10.1128/spectrum.02192-23openalex-snapshot
Secreted NS1 proteins of tick-borne encephalitis virus and West Nile virus block dendritic cell activation and effector functions
inferred← citeshttps://doi.org/10.1155/2012/379738openalex-snapshot
Approaches for the Development of Rapid Serological Assays for Surveillance and Diagnosis of Infections Caused by Zoonotic Flaviviruses of the Japanese Encephalitis Virus Serocomplex
inferred← citeshttps://doi.org/10.1155/2015/376230openalex-snapshot
The Global Ecology and Epidemiology of West Nile Virus
inferred← citeshttps://doi.org/10.1159/000328320openalex-snapshot
West Nile Virus: The Complex Biology of an Emerging Pathogen
inferred← citeshttps://doi.org/10.1159/000452160openalex-snapshot
Nonstructural Protein 1 of Tick-Borne Encephalitis Virus Induces Oxidative Stress and Activates Antioxidant Defense by the Nrf2/ARE Pathway
inferred← citeshttps://doi.org/10.11604/pamj.2016.23.116.7249openalex-snapshot
Analysis of Culex and Aedes mosquitoes in southwestern Nigeria revealed no West Nile virus activity
inferred← citeshttps://doi.org/10.11606/d.17.2019.tde-30052019-154431openalex-snapshot
Estudo do efeito adjuvante do peptídeo derivado da proteína NS3 na resposta imunológica de camundongos vacinados com vírus Zika inativado
inferred← citeshttps://doi.org/10.11606/d.85.2018.tde-26102017-123523openalex-snapshot
Renaturação das proteínas não estruturais 1(NS1) dos vírus da zika e da dengue utilizando altas pressões
inferred← citeshttps://doi.org/10.1177/1535370216675772openalex-snapshot
Viral-derived complement inhibitors: current status and potential role in immunomodulation
inferred← citeshttps://doi.org/10.1186/1297-9716-43-16openalex-snapshot
Recent progress in West Nile virus diagnosis and vaccination
inferred← citeshttps://doi.org/10.1186/1471-2180-11-160openalex-snapshot
Identification of two linear B-cell epitopes from West Nile virus NS1 by screening a phage-displayed random peptide library
inferred← citeshttps://doi.org/10.1186/1742-2094-11-97openalex-snapshot
miR-155 induction in microglial cells suppresses Japanese encephalitis virus replication and negatively modulates innate immune responses
inferred← citeshttps://doi.org/10.1186/1743-422x-10-339openalex-snapshot
Non-structural protein-1 is required for West Nile virus replication complex formation and viral RNA synthesis
inferred← citeshttps://doi.org/10.1186/1743-422x-9-135openalex-snapshot
Protective immunity to Japanese encephalitis virus associated with anti-NS1 antibodies in a mouse model
inferred← citeshttps://doi.org/10.1186/s12014-019-9227-3openalex-snapshot
Characterization of the plasma proteome of nonhuman primates during Ebola virus disease or melioidosis: a host response comparison
inferred← citeshttps://doi.org/10.1186/s12985-016-0590-7openalex-snapshot
Flavivirus NS1: a multifaceted enigmatic viral protein
inferred← citeshttps://doi.org/10.1186/s13071-015-1210-xopenalex-snapshot
Ixodes scapularis and Ixodes ricinus tick cell lines respond to infection with tick-borne encephalitis virus: transcriptomic and proteomic analysis
inferred← citeshttps://doi.org/10.1309/lm5yws85njpcweswopenalex-snapshot
Overview of theFlaviviridaeWith an Emphasis on the Japanese Encephalitis Group Viruses
inferred← citeshttps://doi.org/10.1360/tb-2024-0305openalex-snapshot
寨卡病毒E蛋白和NS1蛋白关键氨基酸突变可促进病毒在小鼠睾丸中的复制
inferred← citeshttps://doi.org/10.1371/journal.pntd.0004277openalex-snapshot
Cooperation between CD4+ T Cells and Humoral Immunity Is Critical for Protection against Dengue Using a DNA Vaccine Based on the NS1 Antigen
inferred← citeshttps://doi.org/10.1371/journal.pntd.0004938openalex-snapshot
West Nile Virus Temperature Sensitivity and Avian Virulence Are Modulated by NS1-2B Polymorphisms
inferred← citeshttps://doi.org/10.1371/journal.pntd.0012823openalex-snapshot
The Japanese encephalitis virus NS1′ protein facilitates virus infection in mosquitoes
inferred← citeshttps://doi.org/10.1371/journal.pone.0001400openalex-snapshot
Variability and Action Mechanism of a Family of Anticomplement Proteins in Ixodes ricinus
inferred← citeshttps://doi.org/10.1371/journal.pone.0006782openalex-snapshot
Alternative Complement Pathway Deregulation Is Correlated with Dengue Severity
inferred← citeshttps://doi.org/10.1371/journal.pone.0031434openalex-snapshot
Comprehensive Mapping of Common Immunodominant Epitopes in the West Nile Virus Nonstructural Protein 1 Recognized by Avian Antibody Responses
inferred← citeshttps://doi.org/10.1371/journal.pone.0057514openalex-snapshot
Mapping the Interactions of Dengue Virus NS1 Protein with Human Liver Proteins Using a Yeast Two-Hybrid System: Identification of C1q as an Interacting Partner
inferred← citeshttps://doi.org/10.1371/journal.pone.0266136openalex-snapshot
Cross-reactive antibodies targeting surface-exposed non-structural protein 1 (NS1) of dengue virus-infected cells recognize epitopes on the spaghetti loop of the β-ladder domain
inferred← citeshttps://doi.org/10.1371/journal.ppat.0030183openalex-snapshot
Secreted NS1 of Dengue Virus Attaches to the Surface of Cells via Interactions with Heparan Sulfate and Chondroitin Sulfate E
inferred← citeshttps://doi.org/10.1371/journal.ppat.1000614openalex-snapshot
A Mouse Model for Studying Viscerotropic Disease Caused by Yellow Fever Virus Infection
inferred← citeshttps://doi.org/10.1371/journal.ppat.1004447openalex-snapshot
Programmed Ribosomal Frameshift Alters Expression of West Nile Virus Genes and Facilitates Virus Replication in Birds and Mosquitoes
inferred← citeshttps://doi.org/10.1371/journal.ppat.1005277openalex-snapshot
Dengue Virus Non-structural Protein 1 Modulates Infectious Particle Production via Interaction with the Structural Proteins
inferred← citeshttps://doi.org/10.1371/journal.ppat.1012844openalex-snapshot
Key virulence factors responsible for differences in pathogenicity between clinically proven live-attenuated Japanese encephalitis vaccine SA14-14-2 and its pre-attenuated highly virulent parent SA14
inferred← citeshttps://doi.org/10.1371/journal.ppat.1014408openalex-snapshot
N-linked glycosylation of NS1 protein modulates progeny virion assembly in orthoflaviviruses
inferred← citeshttps://doi.org/10.1517/17460441.2012.673579openalex-snapshot
Novel approaches to flavivirus drug discovery
inferred← citeshttps://doi.org/10.15212/zoonoses-2026-0038openalex-snapshot
NS1 in Mosquito-Borne Flaviviruses: Roles in Viral Life Cycles, Pathogenesis, and Therapeutic Development
inferred← citeshttps://doi.org/10.15252/embj.201695290openalex-snapshot
Contribution of intertwined loop to membrane association revealed by Zika virus full‐length NS1 structure
inferred← citeshttps://doi.org/10.15252/embr.202153600openalex-snapshot
Dengue virus NS1 protein conveys pro‐inflammatory signals by docking onto high‐density lipoproteins
inferred← citeshttps://doi.org/10.2217/fmb.14.67openalex-snapshot
Technologies for the Development of West Nile Virus Vaccines
inferred← citeshttps://doi.org/10.2217/fvl-2019-0037openalex-snapshot
Evasion Strategies of Zika Virus Antagonizing Host Innate Immunity
inferred← citeshttps://doi.org/10.2217/fvl.10.60openalex-snapshot
Virus–Complement Interactions: An Assiduous Struggle for Dominance
inferred← citeshttps://doi.org/10.2222/jsv.61.221openalex-snapshot
Flaviviruses
inferred← citeshttps://doi.org/10.25560/25758openalex-snapshot
Factors that influence the severity of Dengue infection
inferred← citeshttps://doi.org/10.25904/1912/2151openalex-snapshot
The Antiviral Properties of Melaleuca alternifolia concentrate (MAC) against West Nile virus
inferred← citeshttps://doi.org/10.2741/3432openalex-snapshot
The host immunologic response to West Nile encephalitis virus
inferred← citeshttps://doi.org/10.2807/ese.16.10.19812-enopenalex-snapshot
Increasing West Nile virus antibody titres in central European plasma donors from 2006 to 2010
inferred← citeshttps://doi.org/10.32657/10220/46782openalex-snapshot
Structural and biochemical characterization of non-structural protein 3 from flavivirus
inferred← citeshttps://doi.org/10.3389/fcimb.2021.701362openalex-snapshot
Interactions Between Pathogenic Burkholderia and the Complement System: A Review of Potential Immune Evasion Mechanisms
inferred← citeshttps://doi.org/10.3389/fcimb.2025.1690827openalex-snapshot
West Nile virus unmasked: from gene variability to future challenges
inferred← citeshttps://doi.org/10.3389/fimmu.2020.01450openalex-snapshot
Viral Evasion of the Complement System and Its Importance for Vaccines and Therapeutics
inferred← citeshttps://doi.org/10.3389/fimmu.2020.569549openalex-snapshot
Interference of the Zika Virus E-Protein With the Membrane Attack Complex of the Complement System
inferred← citeshttps://doi.org/10.3389/fimmu.2020.573583openalex-snapshot
In the Crosshairs: RNA Viruses OR Complement?
inferred← citeshttps://doi.org/10.3389/fimmu.2021.602277openalex-snapshot
Hijacking Factor H for Complement Immune Evasion
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1205002openalex-snapshot
Secretory pathways and multiple functions of nonstructural protein 1 in flavivirus infection
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1281096openalex-snapshot
Microbial evasion of the complement system: a continuous and evolving story
inferred← citeshttps://doi.org/10.3389/fimmu.2024.1135490openalex-snapshot
The human factor H protein family – an update
inferred← citeshttps://doi.org/10.3389/fimmu.2024.1352022openalex-snapshot
Mapping the interaction sites of human and avian influenza A viruses and complement factor H
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