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ALIX-CHMP4 interactions in the human ESCRT pathway

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1006/jmbi.1993.1351openalex-snapshot

Main-chain Bond Lengths and Bond Angles in Protein Structures

inferredcites →https://doi.org/10.1016/j.abb.2003.09.038openalex-snapshot

CHMP4b is a major binding partner of the ALG-2-interacting protein Alix among the three CHMP4 isoforms

inferredcites →https://doi.org/10.1016/j.cell.2007.01.035openalex-snapshot

Structural and Biochemical Studies of ALIX/AIP1 and Its Role in Retrovirus Budding

inferredcites →https://doi.org/10.1016/j.cub.2007.10.045openalex-snapshot

A Novel Requirement for C. elegans Alix/ALX-1 in RME-1-Mediated Membrane Transport

inferredcites →https://doi.org/10.1016/j.devcel.2005.04.001openalex-snapshot

Structural Basis for Endosomal Targeting by the Bro1 Domain

inferredcites →https://doi.org/10.1016/j.devcel.2006.03.013openalex-snapshot

Structural Basis for Budding by the ESCRT-III Factor CHMP3

inferredcites →https://doi.org/10.1016/j.devcel.2007.10.021openalex-snapshot

ESCRT-III Family Members Stimulate Vps4 ATPase Activity Directly or via Vta1

inferredcites →https://doi.org/10.1016/j.febslet.2006.05.005openalex-snapshot

POSH, a scaffold protein for JNK signaling, binds to ALG‐2 and ALIX in Drosophila

inferredcites →https://doi.org/10.1016/j.pep.2005.01.016openalex-snapshot

Protein production by auto-induction in high-density shaking cultures

inferredcites →https://doi.org/10.1016/j.tcb.2006.08.003openalex-snapshot

Intra-endosomal membrane traffic

inferredcites →https://doi.org/10.1016/j.virol.2005.09.044openalex-snapshot

Late budding domains and host proteins in enveloped virus release

inferredcites →https://doi.org/10.1016/j.virol.2006.12.017openalex-snapshot

The conserved carboxyl terminus of human parainfluenza virus type 2 V protein plays an important role in virus growth

inferredcites →https://doi.org/10.1016/j.virol.2007.03.039openalex-snapshot

Sendai virus budding in the course of an infection does not require Alix and VPS4A host factors

inferredcites →https://doi.org/10.1016/j.ygeno.2006.04.003openalex-snapshot

A systematic analysis of human CHMP protein interactions: Additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex

inferredcites →https://doi.org/10.1016/s0076-6879(97)76066-xopenalex-snapshot

[20] Processing of X-ray diffraction data collected in oscillation mode

inferredcites →https://doi.org/10.1016/s0092-8674(03)00653-6openalex-snapshot

AIP1/ALIX Is a Binding Partner for HIV-1 p6 and EIAV p9 Functioning in Virus Budding

inferredcites →https://doi.org/10.1016/s0092-8674(03)00714-1openalex-snapshot

The Protein Network of HIV Budding

inferredcites →https://doi.org/10.1038/nature06171openalex-snapshot

Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4

inferredcites →https://doi.org/10.1038/nature06172openalex-snapshot

ESCRT-III recognition by VPS4 ATPases

inferredcites →https://doi.org/10.1038/nrm2162openalex-snapshot

The emerging shape of the ESCRT machinery

inferredcites →https://doi.org/10.1038/nsmb1203openalex-snapshot

Structural basis for viral late-domain binding to Alix

inferredcites →https://doi.org/10.1038/nsmb1319openalex-snapshot

Structural and functional studies of ALIX interactions with YPXnL late domains of HIV-1 and EIAV

inferredcites →https://doi.org/10.1038/sj.emboj.7601850openalex-snapshot

Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis

inferredcites →https://doi.org/10.1042/bc20050007openalex-snapshot

Do Alix and ALG‐2 really control endosomes for better or for worse?

inferredcites →https://doi.org/10.1042/bj20031347openalex-snapshot

Structure and function of human Vps20 and Snf7 proteins

inferredcites →https://doi.org/10.1073/pnas.0603788103openalex-snapshot

Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 budding

inferredcites →https://doi.org/10.1073/pnas.0704000104openalex-snapshot

Involvement of host cellular multivesicular body functions in hepatitis B virus budding

inferredcites →https://doi.org/10.1073/pnas.2133846100openalex-snapshot

Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins

inferredcites →https://doi.org/10.1074/jbc.m204019200openalex-snapshot

Alix (ALG-2-interacting Protein X), a Protein Involved in Apoptosis, Binds to Endophilins and Induces Cytoplasmic Vacuolization

inferredcites →https://doi.org/10.1074/jbc.m301604200openalex-snapshot

The ALG-2-interacting Protein Alix Associates with CHMP4b, a Human Homologue of Yeast Snf7 That Is Involved in Multivesicular Body Sorting

inferredcites →https://doi.org/10.1074/jbc.m309243200openalex-snapshot

Alix, a Protein Regulating Endosomal Trafficking, Is Involved in Neuronal Death

inferredcites →https://doi.org/10.1074/jbc.m602263200openalex-snapshot

Involvement of the Conserved Adaptor Protein Alix in Actin Cytoskeleton Assembly

inferredcites →https://doi.org/10.1074/jbc.m607489200openalex-snapshot

An Alix Fragment Potently Inhibits HIV-1 Budding

inferredcites →https://doi.org/10.1074/jbc.m704009200openalex-snapshot

The MIT Domain of UBPY Constitutes a CHMP Binding and Endosomal Localization Signal Required for Efficient Epidermal Growth Factor Receptor Degradation

inferredcites →https://doi.org/10.1083/jcb.200707031openalex-snapshot

Plasma membrane deformation by circular arrays of ESCRT-III protein filaments

inferredcites →https://doi.org/10.1091/mbc.e04-08-0666openalex-snapshot

Multivesicular Body-ESCRT Components Function in pH Response Regulation in Saccharomyces cerevisiae and Candida albicans

inferredcites →https://doi.org/10.1093/jb/mvh014openalex-snapshot

The Penta-EF-Hand Protein ALG-2 Interacts with a Region Containing PxY Repeats in Alix/AIP1, Which Is Required for the Subcellular Punctate Distribution of the Amino-Terminal Truncation Form of Alix/AIP1

inferredcites →https://doi.org/10.1107/s0021889893002729openalex-snapshot

TLSANL: TLS parameter-analysis program for segmented anisotropic refinement of macromolecular structures

inferredcites →https://doi.org/10.1107/s0108767390010224openalex-snapshot

Improved methods for building protein models in electron density maps and the location of errors in these models

inferredcites →https://doi.org/10.1107/s0907444904019158openalex-snapshot

Coot : model-building tools for molecular graphics

inferredcites →https://doi.org/10.1107/s0907444994003112openalex-snapshot

The CCP4 suite: programs for protein crystallography

inferredcites →https://doi.org/10.1107/s090744499801405xopenalex-snapshot

Efficient anisotropic refinement of macromolecular structures using FFT

inferredcites →https://doi.org/10.1111/j.1600-0854.2004.00169.xopenalex-snapshot

Protein–Protein Interactions of ESCRT Complexes in the Yeast Saccharomyces cerevisiae

inferredcites →https://doi.org/10.1111/j.1600-0854.2004.0167.xopenalex-snapshot

Degradation of AP2 During Reticulocyte Maturation Enhances Binding of Hsc70 and Alix to a Common Site on TfR for Sorting into Exosomes

inferredcites →https://doi.org/10.1111/j.1742-4658.2007.06230.xopenalex-snapshot

Brox, a novel farnesylated Bro1 domain‐containing protein that associates with charged multivesicular body protein 4 (CHMP4)

inferredcites →https://doi.org/10.1126/science.1143422openalex-snapshot

Parallels Between Cytokinesis and Retroviral Budding: A Role for the ESCRT Machinery

inferredcites →https://doi.org/10.1128/jvi.00314-07openalex-snapshot

Potent Rescue of Human Immunodeficiency Virus Type 1 Late Domain Mutants by ALIX/AIP1 Depends on Its CHMP4 Binding Site

inferredcites →https://doi.org/10.1128/jvi.01912-07openalex-snapshot

Human Immunodeficiency Virus Type 1 Gag Engages the Bro1 Domain of ALIX/AIP1 through the Nucleocapsid

inferredcites →https://doi.org/10.1128/jvi.02218-06openalex-snapshot

The YLDL Sequence within Sendai Virus M Protein Is Critical for Budding of Virus-Like Particles and Interacts with Alix/AIP1 Independently of C Protein

inferredcites →https://doi.org/10.1128/mcb.23.5.1647-1655.2003openalex-snapshot

YPXL/I Is a Protein Interaction Motif Recognized by Aspergillus PalA and Its Human Homologue, AIP1/Alix

inferredcites →https://doi.org/10.1128/mcb.24.20.8981-8993.2004openalex-snapshot

Alix/AIP1 Antagonizes Epidermal Growth Factor Receptor Downregulation by the Cbl-SETA/CIN85 Complex

inferredcites →https://doi.org/10.1146/annurev.biophys.35.040405.102126openalex-snapshot

THE ESCRT COMPLEXES: Structure and Mechanism of a Membrane-Trafficking Network

inferredcites →https://doi.org/10.1242/jcs.00395openalex-snapshot

Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae

inferredcites →https://doi.org/10.1242/jcs.00522openalex-snapshot

SETA/CIN85/Ruk and its binding partner AIP1 associate with diverse cytoskeletal elements, including FAKs, and modulate cell adhesion

inferredcites →https://doi.org/10.1242/jcs.02382openalex-snapshot

Alix regulates cortical actin and the spatial distribution of endosomes

inferredcites →https://doi.org/10.1271/bbb.69.861openalex-snapshot

Identification of Rab GTPase-Activating Protein-Like Protein (RabGAPLP) as a Novel Alix/AIP1-Interacting Protein

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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A Mechanism for ER Exit Site Delivery Into Lysosomes Involving COPII, ALG2 and ESCRTs

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Bro1 family proteins harmonize cargo sorting with vesicle formation

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Mechanism of Centrosomal Protein 55 (CEP55) Loading Into Exosomes

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inferred← citeshttps://doi.org/10.1007/978-1-4614-7729-7_5openalex-snapshot

HIV-1 Budding

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The Molecular Convergence of Birdsong and Speech

inferred← citeshttps://doi.org/10.1007/978-3-030-67171-6_2openalex-snapshot

Biogenesis of Extracellular Vesicles

inferred← citeshttps://doi.org/10.1007/978-3-319-96704-2_4openalex-snapshot

ESCRT and Membrane Protein Ubiquitination

inferred← citeshttps://doi.org/10.1007/s00018-012-1035-0openalex-snapshot

Dynamics of ESCRT proteins

inferred← citeshttps://doi.org/10.1007/s00018-023-04864-yopenalex-snapshot

Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesis

inferred← citeshttps://doi.org/10.1007/s10571-016-0366-zopenalex-snapshot

Introduction to Extracellular Vesicles: Biogenesis, RNA Cargo Selection, Content, Release, and Uptake

inferred← citeshttps://doi.org/10.1007/s11060-013-1084-8openalex-snapshot

Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies

inferred← citeshttps://doi.org/10.1007/s12250-019-00157-6openalex-snapshot

Proteomic Profiling of Purified Rabies Virus Particles

inferred← citeshttps://doi.org/10.1007/s13238-011-1053-yopenalex-snapshot

Hrs inhibits citron kinase-mediated HIV-1 budding via its FYVE domain

inferred← citeshttps://doi.org/10.1007/s40618-020-01286-6openalex-snapshot

BROX haploinsufficiency in familial nonmedullary thyroid cancer

inferred← citeshttps://doi.org/10.1016/b978-0-12-386487-1.00004-3openalex-snapshot

Reconstituting Multivesicular Body Biogenesis with Purified Components

inferred← citeshttps://doi.org/10.1016/b978-0-323-89911-6.00003-0openalex-snapshot

ESCRT-mediated plasma membrane shaping

inferred← citeshttps://doi.org/10.1016/b978-0-323-99507-8.00067-6openalex-snapshot

ESCRT-mediated membrane fission

inferred← citeshttps://doi.org/10.1016/b978-0-443-15717-2.00091-3openalex-snapshot

Stem Cell-Derived Extracellular Vesicles and Their Potential Role in Medical Applications

inferred← citeshttps://doi.org/10.1016/j.antiviral.2023.105786openalex-snapshot

ESCRT machinery and virus infection

inferred← citeshttps://doi.org/10.1016/j.bbadva.2023.100109openalex-snapshot

WITHDRAWN: CHMP4B and VSP4A reverse GSDMD-mediated pyroptosis by cell membrane remodeling in endometrial carcinoma

inferred← citeshttps://doi.org/10.1016/j.bbagen.2023.130497openalex-snapshot

CHMP4B and VSP4A reverse GSDMD-mediated pyroptosis by cell membrane remodeling in endometrial carcinoma

inferred← citeshttps://doi.org/10.1016/j.bbamcr.2018.07.001openalex-snapshot

Lysosomal N-acetyltransferase interacts with ALIX and is detected in extracellular vesicles

inferred← citeshttps://doi.org/10.1016/j.bbamem.2013.08.020openalex-snapshot

Mutations in the feline immunodeficiency virus envelope glycoprotein confer resistance to a dominant–negative fragment of Tsg101 by enhancing infectivity and cell-to-cell virus transmission

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The ESCRT pathway and HIV-1 budding: A paradigm of viral exploitation of cellular regulation

inferred← citeshttps://doi.org/10.1016/j.bbapap.2013.01.006openalex-snapshot

Analysis of Molecular Recognition Features (MoRFs) in membrane proteins

inferred← citeshttps://doi.org/10.1016/j.bbcan.2019.08.001openalex-snapshot

From squamous intraepithelial lesions to cervical cancer: Circulating microRNAs as potential biomarkers in cervical carcinogenesis

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Role of exosomes in lung cancer: A comprehensive insight from immunomodulation to theragnostic applications

inferred← citeshttps://doi.org/10.1016/j.ceb.2012.10.012openalex-snapshot

Membrane dynamics during cytokinesis

inferred← citeshttps://doi.org/10.1016/j.celbio.2025.100344openalex-snapshot

Engineered exosomes as precision tools for brain-targeted drug delivery and treatment of central nervous system diseases

inferred← citeshttps://doi.org/10.1016/j.celrep.2016.07.068openalex-snapshot

Unique Requirement for ESCRT Factors in Flavivirus Particle Formation on the Endoplasmic Reticulum

inferred← citeshttps://doi.org/10.1016/j.cub.2019.09.025openalex-snapshot

Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding

inferred← citeshttps://doi.org/10.1016/j.devcel.2008.05.014openalex-snapshot

Two Distinct Modes of ESCRT-III Recognition Are Required for VPS4 Functions in Lysosomal Protein Targeting and HIV-1 Budding

inferred← citeshttps://doi.org/10.1016/j.devcel.2012.10.023openalex-snapshot

ALIX Is a Lys63-Specific Polyubiquitin Binding Protein that Functions in Retrovirus Budding

inferred← citeshttps://doi.org/10.1016/j.devcel.2016.01.001openalex-snapshot

Phosphorylation-Dependent Activation of the ESCRT Function of ALIX in Cytokinetic Abscission and Retroviral Budding

inferred← citeshttps://doi.org/10.1016/j.devcel.2024.03.027openalex-snapshot

COPII with ALG2 and ESCRTs control lysosome-dependent microautophagy of ER exit sites

inferred← citeshttps://doi.org/10.1016/j.devcel.2025.03.008openalex-snapshot

Bro1 proteins determine tumor immune evasion and metastasis by controlling secretion or degradation of multivesicular bodies

inferred← citeshttps://doi.org/10.1016/j.exer.2025.110260openalex-snapshot

Corneal stromal cells from patients with keratoconus exhibit alterations in the ESCRT-dependent machinery responsible for multivesicular body formation

inferred← citeshttps://doi.org/10.1016/j.fgb.2010.03.010openalex-snapshot

Characterization of Aspergillus nidulans DidBDid2, a non-essential component of the multivesicular body pathway

inferred← citeshttps://doi.org/10.1016/j.ibmb.2014.11.007openalex-snapshot

The vacuolar protein sorting genes in insects: A comparative genome view

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Mechanistic roles of tyrosine phosphorylation in reversible amyloids, autoinhibition, and endosomal membrane association of ALIX

inferred← citeshttps://doi.org/10.1016/j.jbc.2022.102425openalex-snapshot

Distinct functions of dimeric and monomeric scaffold protein Alix in regulating F-actin assembly and loading of exosomal cargo

inferred← citeshttps://doi.org/10.1016/j.jmb.2011.04.055openalex-snapshot

The Role of Cellular Factors in Promoting HIV Budding

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CC2D1A Is a Regulator of ESCRT-III CHMP4B

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Liaison alcaline: Pals entice non-endosomal ESCRTs to the plasma membrane for pH signaling

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Interaction between the yellow fever virus nonstructural protein NS3 and the host protein Alix contributes to the release of infectious particles

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Exosomes and their implications in central nervous system tumor biology

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ESCRT-dependent cargo sorting at multivesicular endosomes

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ESCRT-dependent control of membrane remodelling during cell division

inferred← citeshttps://doi.org/10.1016/j.str.2009.04.007openalex-snapshot

A Crescent-Shaped ALIX Dimer Targets ESCRT-III CHMP4 Filaments

inferred← citeshttps://doi.org/10.1016/j.str.2011.07.016openalex-snapshot

The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release

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Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B

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Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP

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Knowing when to cut and run: mechanisms that control cytokinetic abscission

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The Abscission Checkpoint: Making It to the Final Cut

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Divergent pathways lead to ESCRT-III-catalyzed membrane fission

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Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery

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Epigenetic modulation of BARD1 to enhance anti-VEGF therapy

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An Integrated Machine Learning Model To Spot Peptide Binding Pockets in 3D Protein Screening

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Molecular Characterization of the Coproduced Extracellular Vesicles in HEK293 during Virus-Like Particle Production

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Multiplexed Quantitative Proteomic Analysis of HEK293 Provides Insights into Molecular Changes Associated with the Cell Density Effect, Transient Transfection, and Virus-Like Particle Production

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A Background Assessable and Correctable Bimolecular Fluorescence Complementation System for Nanoscopic Single-Molecule Imaging of Intracellular Protein–Protein Interactions

inferred← citeshttps://doi.org/10.1038/celldisc.2015.18openalex-snapshot

ALG-2 activates the MVB sorting function of ALIX through relieving its intramolecular interaction

inferred← citeshttps://doi.org/10.1038/emboj.2013.4openalex-snapshot

Structure‐based in silico identification of ubiquitin‐binding domains provides insights into the ALIX‐V:ubiquitin complex and retrovirus budding

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The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

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GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

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Reflecting on a quarter century of HIV research

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Reverse-topology membrane scission by the ESCRT proteins

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Membrane budding and scission by the ESCRT machinery: it's all in the neck

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Host factors involved in retroviral budding and release

inferred← citeshttps://doi.org/10.1038/nrmicro2747openalex-snapshot

The structural biology of HIV-1: mechanistic and therapeutic insights

inferred← citeshttps://doi.org/10.1038/nsmb.1621openalex-snapshot

Structural basis for ESCRT-III protein autoinhibition

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CARM1-mediated hypoxanthine-enriched exosomes rewire inosine metabolism and impair CD8+ T cell antitumor function

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ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity

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A plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis

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Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation

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CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection

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Unravelling the human taste receptor interactome: machine learning and molecular modelling insights into protein-protein interactions

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Ceramide-rich microdomains facilitate nuclear envelope budding for non-conventional exosome formation

inferred← citeshttps://doi.org/10.1038/s41580-019-0177-4openalex-snapshot

The many functions of ESCRTs

inferred← citeshttps://doi.org/10.1038/s41594-022-00867-8openalex-snapshot

Structural basis of CHMP2A–CHMP3 ESCRT-III polymer assembly and membrane cleavage

inferred← citeshttps://doi.org/10.1038/s42003-025-08344-wopenalex-snapshot

The hepatocyte traffic network in the human hepatitis A virus biological cycle from an evolutionary perspective

inferred← citeshttps://doi.org/10.1038/srep26986openalex-snapshot

ALG-2 interacting protein-X (Alix) is essential for clathrin-independent endocytosis and signaling

inferred← citeshttps://doi.org/10.1042/bcj20250148openalex-snapshot

Cutting edge: ESCRT-mediated phagophore closure in mammals

inferred← citeshttps://doi.org/10.1042/bj20090957openalex-snapshot

Analysis of the dual function of the ESCRT-III protein Snf7 in endocytic trafficking and in gene expression

inferred← citeshttps://doi.org/10.1042/bj20100862openalex-snapshot

Decoding the intrinsic mechanism that prohibits ALIX interaction with ESCRT and viral proteins

inferred← citeshttps://doi.org/10.1042/bj20141156openalex-snapshot

Unravelling the pivotal role of Alix in MVB sorting and silencing of the activated EGFR

inferred← citeshttps://doi.org/10.1042/bj20151115openalex-snapshot

ESCRT-III on endosomes: new functions, new activation pathway

inferred← citeshttps://doi.org/10.1042/bsr20220765openalex-snapshot

Role of calcium-sensor proteins in cell membrane repair

inferred← citeshttps://doi.org/10.1042/bst0370143openalex-snapshot

Regulation of Vps4 ATPase activity by ESCRT-III

inferred← citeshttps://doi.org/10.1042/bst0370156openalex-snapshot

Structure and function of ESCRT-III

inferred← citeshttps://doi.org/10.1042/bst0370161openalex-snapshot

Piecing together the ESCRTs

inferred← citeshttps://doi.org/10.1042/bst0370181openalex-snapshot

The ESCRT pathway and HIV-1 budding

inferred← citeshttps://doi.org/10.1042/bst0381397openalex-snapshot

The ESCRT machinery: a cellular apparatus for sorting and scission

inferred← citeshttps://doi.org/10.1042/bst20160479openalex-snapshot

Growing functions of the ESCRT machinery in cell biology and viral replication

inferred← citeshttps://doi.org/10.1042/bst20180026openalex-snapshot

The role of VPS4 in ESCRT-III polymer remodeling

inferred← citeshttps://doi.org/10.1042/cs20220149openalex-snapshot

Preeclampsia and syncytiotrophoblast membrane extracellular vesicles (STB-EVs)

inferred← citeshttps://doi.org/10.1073/pnas.1619519114openalex-snapshot

Protein composition of the hepatitis A virus quasi-envelope

inferred← citeshttps://doi.org/10.1073/pnas.1805504115openalex-snapshot

A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability

inferred← citeshttps://doi.org/10.1073/pnas.2010635117openalex-snapshot

Proline-rich domain of human ALIX contains multiple TSG101-UEV interaction sites and forms phosphorylation-mediated reversible amyloids

inferred← citeshttps://doi.org/10.1073/pnas.2205590119openalex-snapshot

In vitro reconstitution of calcium-dependent recruitment of the human ESCRT machinery in lysosomal membrane repair

inferred← citeshttps://doi.org/10.1074/jbc.m114.560193openalex-snapshot

Interaction of HIV-1 Nef Protein with the Host Protein Alix Promotes Lysosomal Targeting of CD4 Receptor

inferred← citeshttps://doi.org/10.1074/jbc.m116.747618openalex-snapshot

Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner

inferred← citeshttps://doi.org/10.1080/15548627.2023.2169309openalex-snapshot

Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis

inferred← citeshttps://doi.org/10.1080/19768354.2024.2380294openalex-snapshot

ESCRT-III: a versatile membrane remodeling machinery and its implications in cellular processes and diseases

inferred← citeshttps://doi.org/10.1080/21691401.2019.1629950openalex-snapshot

Vacuolar protein sorting 4B regulates the proliferation and odontoblastic differentiation of human dental pulp stem cells through the Wnt-β-catenin signalling pathway

inferred← citeshttps://doi.org/10.1083/jcb.201007018openalex-snapshot

Bro1 binding to Snf7 regulates ESCRT-III membrane scission activity in yeast

inferred← citeshttps://doi.org/10.1083/jcb.201507009openalex-snapshot

ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission

inferred← citeshttps://doi.org/10.1083/jcb.201604003openalex-snapshot

Membrane curvature in cell biology: An integration of molecular mechanisms

inferred← citeshttps://doi.org/10.1083/jcb.201709005openalex-snapshot

The ESCRT protein Chmp4c regulates mitotic spindle checkpoint signaling

inferred← citeshttps://doi.org/10.1083/jcb.201904113openalex-snapshot

ALIX- and ESCRT-III–dependent sorting of tetraspanins to exosomes

inferred← citeshttps://doi.org/10.1083/jcb.202102070openalex-snapshot

Bro1 stimulates Vps4 to promote intralumenal vesicle formation during multivesicular body biogenesis

inferred← citeshttps://doi.org/10.1083/jcb.202601189openalex-snapshot

Components of an ESCRT-independent nuclear envelope assembly pathway

inferred← citeshttps://doi.org/10.1091/mbc.e15-05-0284openalex-snapshot

The α-arrestin ARRDC3 mediates ALIX ubiquitination and G protein–coupled receptor lysosomal sorting

inferred← citeshttps://doi.org/10.1101/049148openalex-snapshot

Chm7 and Heh1 form a nuclear envelope subdomain for nuclear pore complex quality control

inferred← citeshttps://doi.org/10.1101/2020.07.27.223255openalex-snapshot

Bro1 stimulates Vps4 activity to promote Intralumenal Vesicle Formation during Multivesicular Body biogenesis

inferred← citeshttps://doi.org/10.1101/2020.10.07.330290openalex-snapshot

Abscission Checkpoint Bodies Reveal a New Facet of Abscission Checkpoint Control

inferred← citeshttps://doi.org/10.1101/2022.02.09.479761openalex-snapshot

Ceramide-Rich Microdomains Facilitate Nuclear Envelope Budding during the Biogenesis of LTB 4 -containing Exosomes

inferred← citeshttps://doi.org/10.1101/2025.10.15.682724openalex-snapshot

Silencing the signal: The metastasis suppressor NDRG1 disrupts exosome-mediated crosstalk in pancreatic cancer

inferred← citeshttps://doi.org/10.1101/cshperspect.a006924openalex-snapshot

HIV-1 Assembly, Budding, and Maturation

inferred← citeshttps://doi.org/10.1101/cshperspect.a022343openalex-snapshot

Cytokinesis in Metazoa and Fungi

inferred← citeshttps://doi.org/10.1105/tpc.15.00393openalex-snapshot

ESCRT-III-Associated Protein ALIX Mediates High-Affinity Phosphate Transporter Trafficking to Maintain Phosphate Homeostasis in Arabidopsis

inferred← citeshttps://doi.org/10.1111/acel.70184openalex-snapshot

Aerobic Exercise Attenuates Autophagy‐Lysosomal Flux Deficits via β2‐AR‐Mediated ESCRT‐III Subunit CHMP4B in Mice With Human MAPT P301L

inferred← citeshttps://doi.org/10.1111/boc.202200116openalex-snapshot

Do different exosome biogenesis pathways and selective cargo enrichment contribute to exosomal heterogeneity?

inferred← citeshttps://doi.org/10.1111/cmi.13161openalex-snapshot

ESCRT‐II functions by linking to ESCRT‐I in human immunodeficiency virus‐1 budding

inferred← citeshttps://doi.org/10.1111/dgd.12023openalex-snapshot

Identification and characterization of P lAlix, the A lix homologue from the M editerranean sea urchin P aracentrotus lividus

inferred← citeshttps://doi.org/10.1111/febs.12243openalex-snapshot

Analysis of limited proteolytic activity of calpain‐7 using non‐physiological substrates in mammalian cells

inferred← citeshttps://doi.org/10.1111/febs.13688openalex-snapshot

ESCRT‐III and Vps4: a dynamic multipurpose tool for membrane budding and scission

inferred← citeshttps://doi.org/10.1111/j.1462-5822.2010.01557.xopenalex-snapshot

Alix regulates egress of hepatitis B virus naked capsid particles in an ESCRT-independent manner

inferred← citeshttps://doi.org/10.1111/j.1742-4658.2012.08560.xopenalex-snapshot

Evolutionary and physical linkage between calpains and penta‐EF‐hand Ca 2+ ‐binding proteins

inferred← citeshttps://doi.org/10.1111/odi.12861openalex-snapshot

Dentin dysplasia type I—A dental disease with genetic heterogeneity

inferred← citeshttps://doi.org/10.1111/tra.12237openalex-snapshot

Molecular Insights into Rab7‐Mediated Endosomal Recruitment of Core Retromer: Deciphering the Role of Vps26 and Vps35

inferred← citeshttps://doi.org/10.1111/tra.12828openalex-snapshot

Bro1 binds the Vps20 subunit of ESCRT‐III and promotes ESCRT‐III regulation by Doa4

inferred← citeshttps://doi.org/10.1126/sciadv.adg3913openalex-snapshot

Reversible phase separation of ESCRT protein ALIX through tyrosine phosphorylation

inferred← citeshttps://doi.org/10.1126/science.1162042openalex-snapshot

Midbody Targeting of the ESCRT Machinery by a Noncanonical Coiled Coil in CEP55

inferred← citeshttps://doi.org/10.1126/science.1247136openalex-snapshot

ESCRT Machinery Is Required for Plasma Membrane Repair

inferred← citeshttps://doi.org/10.1128/ec.00241-13openalex-snapshot

Interaction Maps of the Saccharomyces cerevisiae ESCRT-III Protein Snf7

inferred← citeshttps://doi.org/10.1128/jvi.00392-19openalex-snapshot

Seeking Closure: How Do Herpesviruses Recruit the Cellular ESCRT Apparatus?

inferred← citeshttps://doi.org/10.1128/jvi.00815-21openalex-snapshot

Structural Insight into the Interaction of Sendai Virus C Protein with Alix To Stimulate Viral Budding

inferred← citeshttps://doi.org/10.1128/jvi.00844-25openalex-snapshot

ESCRT-III is recruited by human herpesvirus 6A nuclear egress complex to promote nuclear egress of the nucleocapsid

inferred← citeshttps://doi.org/10.1128/jvi.01260-12openalex-snapshot

Identification of the HIV-1 NC Binding Interface in Alix Bro1 Reveals a Role for RNA

inferred← citeshttps://doi.org/10.1128/jvi.01562-10openalex-snapshot

Basic Residues in the Nucleocapsid Domain of Gag Are Critical for Late Events of HIV-1 Budding

inferred← citeshttps://doi.org/10.1128/jvi.01624-21openalex-snapshot

Roles of ESCRT Proteins ALIX and CHMP4A and Their Interplay with Interferon-Stimulated Gene 15 during Tick-Borne Flavivirus Infection

inferred← citeshttps://doi.org/10.1128/jvi.01641-19openalex-snapshot

The ESCRT-II Subunit EAP20/VPS25 and the Bro1 Domain Proteins HD-PTP and BROX Are Individually Dispensable for Herpes Simplex Virus 1 Replication

inferred← citeshttps://doi.org/10.1128/jvi.01683-10openalex-snapshot

Identification and Structural Characterization of the ALIX-Binding Late Domains of Simian Immunodeficiency Virus SIV mac239 and SIV agmTan-1

inferred← citeshttps://doi.org/10.1128/jvi.02019-19openalex-snapshot

Alix-Mediated Rescue of Feline Immunodeficiency Virus Budding Differs from That Observed with Human Immunodeficiency Virus

inferred← citeshttps://doi.org/10.1128/jvi.02653-10openalex-snapshot

Activation of the Retroviral Budding Factor ALIX

inferred← citeshttps://doi.org/10.1128/jvi.06539-11openalex-snapshot

Regulation of CHMP4/ESCRT-III Function in Human Immunodeficiency Virus Type 1 Budding by CC2D1A

inferred← citeshttps://doi.org/10.1128/jvi.07105-11openalex-snapshot

Budding of Retroviruses Utilizing Divergent L Domains Requires Nucleocapsid

inferred← citeshttps://doi.org/10.1128/mbio.02183-20openalex-snapshot

Novel Role for ESCRT-III Component CHMP4C in the Integrity of the Endocytic Network Utilized for Herpes Simplex Virus Envelopment

inferred← citeshttps://doi.org/10.1136/jmedgenet-2015-103619openalex-snapshot

A splicing mutation in VPS4B causes dentin dysplasia I

inferred← citeshttps://doi.org/10.1139/bcb-2017-0322openalex-snapshot

Structure and functions of His domain protein tyrosine phosphatase in receptor trafficking and cancer

inferred← citeshttps://doi.org/10.1146/annurev-biochem-072909-101058openalex-snapshot

Membrane Fission Reactions of the Mammalian ESCRT Pathway

inferred← citeshttps://doi.org/10.1146/annurev-cellbio-092910-154152openalex-snapshot

Multivesicular Body Morphogenesis

inferred← citeshttps://doi.org/10.1146/annurev-cellbio-100616-060600openalex-snapshot

Structures, Functions, and Dynamics of ESCRT-III/Vps4 Membrane Remodeling and Fission Complexes

inferred← citeshttps://doi.org/10.1146/annurev-physiol-042222-024535openalex-snapshot

Exosome-Mediated Impact on Systemic Metabolism

inferred← citeshttps://doi.org/10.1155/2010/419849openalex-snapshot

Immunology and Cell Biology of Parasitic Diseases

inferred← citeshttps://doi.org/10.1155/2012/657942openalex-snapshot

EhADH112 Is a Bro1 Domain-Containing Protein Involved in theEntamoeba histolyticaMultivesicular Bodies Pathway

inferred← citeshttps://doi.org/10.1159/000551438openalex-snapshot

The Human Immunodeficiency Virus Type 1 Budding Machinery: Deconstructing the Endosomal Sorting Complexes Required for Transport-Mediated Scission Pathway

inferred← citeshttps://doi.org/10.1186/1742-4690-10-104openalex-snapshot

ESCRT requirements for EIAV budding

inferred← citeshttps://doi.org/10.1186/1742-4690-10-143openalex-snapshot

The S40 residue in HIV-1 Gag p6 impacts local and distal budding determinants, revealing additional late domain activities

inferred← citeshttps://doi.org/10.1186/1742-4690-10-5openalex-snapshot

Wrapping up the bad news – HIV assembly and release

inferred← citeshttps://doi.org/10.1186/s12931-020-01423-yopenalex-snapshot

Extracellular vesicles: novel communicators in lung diseases

inferred← citeshttps://doi.org/10.1186/s12977-015-0197-xopenalex-snapshot

Evidence that the endosomal sorting complex required for transport-II (ESCRT-II) is required for efficient human immunodeficiency virus-1 (HIV-1) production

inferred← citeshttps://doi.org/10.1186/s13321-025-01055-8openalex-snapshot

Deep learning molecular interaction motifs from receptor structures alone

inferred← citeshttps://doi.org/10.1242/jcs.028308openalex-snapshot

No strings attached: the ESCRT machinery in viral budding and cytokinesis

inferred← citeshttps://doi.org/10.1242/jcs.029884openalex-snapshot

The ESCRT machinery at a glance

inferred← citeshttps://doi.org/10.1242/jcs.241455openalex-snapshot

The ubiquitin hydrolase Doa4 directly binds Snf7 to inhibit recruitment of ESCRT-III remodeling factors in S. cerevisiae

inferred← citeshttps://doi.org/10.1242/jcs.259192openalex-snapshot

His domain protein tyrosine phosphatase and Rabaptin-5 couple endo-lysosomal sorting of EGFR with endosomal maturation

inferred← citeshttps://doi.org/10.1242/jcs.260159openalex-snapshot

Toxoplasma gondii scavenges mammalian host organelles through the usurpation of host ESCRT-III and Vps4A

inferred← citeshttps://doi.org/10.1242/jcs.264719openalex-snapshot

A Golgi-bypass secretion mechanism for proTGFα involving TMED9 and GRASP65

inferred← citeshttps://doi.org/10.1360/ssv-2025-0354openalex-snapshot

Identification, phylogeny, and functional characterization of the ZCPS protein family—a unique component of the ESCRT complex in Asgard archaea

inferred← citeshttps://doi.org/10.1371/journal.pbio.2002354openalex-snapshot

The ESCRT-III pathway facilitates cardiomyocyte release of cBIN1-containing microparticles

inferred← citeshttps://doi.org/10.1371/journal.pcbi.1000274openalex-snapshot

A Factor Graph Nested Effects Model To Identify Networks from Genetic Perturbations

inferred← citeshttps://doi.org/10.1371/journal.pgen.1004904openalex-snapshot

ALIX and ESCRT-III Coordinately Control Cytokinetic Abscission during Germline Stem Cell Division In Vivo

inferred← citeshttps://doi.org/10.1371/journal.pone.0027466openalex-snapshot

Structure of the Bro1 Domain Protein BROX and Functional Analyses of the ALIX Bro1 Domain in HIV-1 Budding

inferred← citeshttps://doi.org/10.1371/journal.pone.0096950openalex-snapshot

ALIX Is Recruited Temporarily into HIV-1 Budding Sites at the End of Gag Assembly

inferred← citeshttps://doi.org/10.1371/journal.pone.0149113openalex-snapshot

Structural Study of the HD-PTP Bro1 Domain in a Complex with the Core Region of STAM2, a Subunit of ESCRT-0

inferred← citeshttps://doi.org/10.1371/journal.pone.0157587openalex-snapshot

ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y1 Purinergic Receptor via a YPX3L Motif

inferred← citeshttps://doi.org/10.1371/journal.ppat.1000339openalex-snapshot

The Nucleocapsid Region of HIV-1 Gag Cooperates with the PTAP and LYPXnL Late Domains to Recruit the Cellular Machinery Necessary for Viral Budding

inferred← citeshttps://doi.org/10.1371/journal.ppat.1001153openalex-snapshot

Functional Interchangeability of Late Domains, Late Domain Cofactors and Ubiquitin in Viral Budding

inferred← citeshttps://doi.org/10.1371/journal.ppat.1002232openalex-snapshot

Old World Arenaviruses Enter the Host Cell via the Multivesicular Body and Depend on the Endosomal Sorting Complex Required for Transport

inferred← citeshttps://doi.org/10.1371/journal.ppat.1004677openalex-snapshot

Super-Resolution Imaging of ESCRT-Proteins at HIV-1 Assembly Sites

inferred← citeshttps://doi.org/10.1371/journal.ppat.1008100openalex-snapshot

NEDD4 family ubiquitin ligases associate with LCMV Z’s PPXY domain and are required for virus budding, but not via direct ubiquitination of Z

inferred← citeshttps://doi.org/10.1371/journal.ppat.1010543openalex-snapshot

Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX

inferred← citeshttps://doi.org/10.14806/ej.18.a.443openalex-snapshot

Analysis of molecular recognition features in membrane proteins

inferred← citeshttps://doi.org/10.1515/bc.2011.091openalex-snapshot

Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis

inferred← citeshttps://doi.org/10.15252/embj.201694574openalex-snapshot

Chm7 and Heh1 collaborate to link nuclear pore complex quality control with nuclear envelope sealing

inferred← citeshttps://doi.org/10.1534/genetics.109.112029openalex-snapshot

Mutational Analysis of Candida albicans SNF7 Reveals Genetically Separable Rim101 and ESCRT Functions and Demonstrates Divergence in bro1-Domain Protein Interactions

inferred← citeshttps://doi.org/10.2217/fmb.11.100openalex-snapshot

Essential and supporting host cell factors for HIV-1 budding

inferred← citeshttps://doi.org/10.3109/10409238.2010.502516openalex-snapshot

The ESCRT complexes

inferred← citeshttps://doi.org/10.3109/10409238.2014.881777openalex-snapshot

The ESCRT machinery: From the plasma membrane to endosomes and back again

inferred← citeshttps://doi.org/10.3389/fcell.2021.634853openalex-snapshot

Potential Roles of Muscle-Derived Extracellular Vesicles in Remodeling Cellular Microenvironment: Proposed Implications of the Exercise-Induced Myokine, Irisin

inferred← citeshttps://doi.org/10.3389/fendo.2022.829103openalex-snapshot

Susceptibility Genes and Chromosomal Regions Associated With Non-Syndromic Familial Non-Medullary Thyroid Carcinoma: Some Pathogenetic and Diagnostic Keys

inferred← citeshttps://doi.org/10.3389/fonc.2024.1286426openalex-snapshot

Chromosomal localization of mutated genes in non-syndromic familial thyroid cancer

inferred← citeshttps://doi.org/10.3390/antiox14010108openalex-snapshot

Targeting Mitochondrial Dysfunction in Cerebral Ischemia: Advances in Pharmacological Interventions

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