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Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ijc.22874openalex-snapshot

Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra‐cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum

inferredcites →https://doi.org/10.1007/s10555-006-9036-9openalex-snapshot

Bone marrow cells in the ‘pre-metastatic niche’: within bone and beyond

inferredcites →https://doi.org/10.1016/j.ccr.2006.10.008openalex-snapshot

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

inferredcites →https://doi.org/10.1016/j.ccr.2009.01.023openalex-snapshot

Cancer Metastasis Is Accelerated through Immunosuppression during Snail-Induced EMT of Cancer Cells

inferredcites →https://doi.org/10.1016/j.ccr.2009.03.016openalex-snapshot

Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion

inferredcites →https://doi.org/10.1016/j.cell.2004.06.006openalex-snapshot

Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis

inferredcites →https://doi.org/10.1016/j.cell.2008.03.027openalex-snapshot

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

inferredcites →https://doi.org/10.1016/j.cytogfr.2006.04.004openalex-snapshot

Signalling and functional diversity within the Axl subfamily of receptor tyrosine kinases

inferredcites →https://doi.org/10.1016/s0065-230x(08)00002-xopenalex-snapshot

TAM Receptor Tyrosine Kinases: Biologic Functions, Signaling, and Potential Therapeutic Targeting in Human Cancer

inferredcites →https://doi.org/10.1023/a:1008999403069openalex-snapshot

Mammography screening in Norway: results from the first screening round in four counties and cost-effectiveness of a modeled nationwide screening

inferredcites →https://doi.org/10.1038/35065016openalex-snapshot

Involvement of chemokine receptors in breast cancer metastasis

inferredcites →https://doi.org/10.1038/nmeth1085openalex-snapshot

Engineering tumors with 3D scaffolds

inferredcites →https://doi.org/10.1038/nrc2131openalex-snapshot

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

inferredcites →https://doi.org/10.1038/nrc2620openalex-snapshot

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

inferredcites →https://doi.org/10.1038/nrc822openalex-snapshot

Epithelial–mesenchymal transitions in tumour progression

inferredcites →https://doi.org/10.1038/nrm1835openalex-snapshot

Complex networks orchestrate epithelial–mesenchymal transitions

inferredcites →https://doi.org/10.1038/sj.onc.1210173openalex-snapshot

A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors

inferredcites →https://doi.org/10.1073/pnas.0510923103openalex-snapshot

Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival

inferredcites →https://doi.org/10.1073/pnas.0603948103openalex-snapshot

Phosphoproteomic analysis of Her2/neu signaling and inhibition

inferredcites →https://doi.org/10.1073/pnas.0808932106openalex-snapshot

Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement

inferredcites →https://doi.org/10.1073/pnas.89.19.9064openalex-snapshot

Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

inferredcites →https://doi.org/10.1093/carcin/bgn104openalex-snapshot

Mechanisms of malignant progression

inferredcites →https://doi.org/10.1101/sqb.2005.70.033openalex-snapshot

The Evolving Portrait of Cancer Metastasis

inferredcites →https://doi.org/10.1158/0008-5472.can-05-0993openalex-snapshot

Multiple Roles for the Receptor Tyrosine Kinase Axl in Tumor Formation

inferredcites →https://doi.org/10.1158/0008-5472.can-07-2661openalex-snapshot

AXL Is a Potential Target for Therapeutic Intervention in Breast Cancer Progression

inferredcites →https://doi.org/10.1158/1078-0432.ccr-07-0862openalex-snapshot

Axl and Growth Arrest–Specific Gene 6 Are Frequently Overexpressed in Human Gliomas and Predict Poor Prognosis in Patients with Glioblastoma Multiforme

inferredcites →https://doi.org/10.1186/1471-2407-8-228openalex-snapshot

Imagable 4T1 model for the study of late stage breast cancer

inferredcites →https://doi.org/10.2353/ajpath.2009.080545openalex-snapshot

Epithelial-Mesenchymal Transition

inferredcites →https://doi.org/10.4161/cbt.8.7.7923openalex-snapshot

The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3155728openalex-extracted

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade During HER2-Positive Breast Cancer Progression

inferred← citeshttps://doi.org/10.2139/ssrn.4178541openalex-extracted

Systemic Infection of Gut Pathobiont Klebsiella pneumoniae Is Prevented by Gas6/Axl Signals in the Intestinal Epithelium

inferred← citeshttps://doi.org/10.1001/jamainternmed.2017.5512openalex-snapshot

Association of Warfarin Use With Lower Overall Cancer Incidence Among Patients Older Than 50 Years

inferred← citeshttps://doi.org/10.1002/1878-0261.13347openalex-snapshot

GALNT2 promotes invasiveness of colorectal cancer cells partly through AXL

inferred← citeshttps://doi.org/10.1002/9780470015902.a0006049.pub2openalex-snapshot

Oncogenic Transcription Factors: Target Genes

inferred← citeshttps://doi.org/10.1002/adbi.202300271openalex-snapshot

Impact of Chemotherapeutic Stress Depends on The Nature of Breast Cancer Spheroid and Induce Behavioral Plasticity to Resistant Population

inferred← citeshttps://doi.org/10.1002/adfm.202006796openalex-snapshot

Bone‐on‐a‐Chip: Microfluidic Technologies and Microphysiologic Models of Bone Tissue

inferred← citeshttps://doi.org/10.1002/advs.202501388openalex-snapshot

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

inferred← citeshttps://doi.org/10.1002/cam4.2846openalex-snapshot

Detection of AXL expression in circulating tumor cells of lung cancer patients using an automated microcavity array system

inferred← citeshttps://doi.org/10.1002/cam4.6843openalex-snapshot

First evidence of AXL expression on circulating tumor cells in metastatic breast cancer patients: A proof‐of‐concept study

inferred← citeshttps://doi.org/10.1002/cjp2.167openalex-snapshot

Greater utility of molecular subtype rather than epithelial‐to‐mesenchymal transition ( EMT ) markers for prognosis in high‐risk non‐muscle‐invasive ( HGT1 ) bladder cancer

inferred← citeshttps://doi.org/10.1002/cncr.25483openalex-snapshot

Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma

inferred← citeshttps://doi.org/10.1002/hep.27492openalex-snapshot

Axl activates autocrine transforming growth factor‐β signaling in hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1002/ijc.28246openalex-snapshot

The receptor tyrosine kinase Axl in cancer: Biological functions and therapeutic implications

inferred← citeshttps://doi.org/10.1002/ijc.29394openalex-snapshot

Multicenter analysis of soluble A xl reveals diagnostic value for very early stage hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1002/ijc.32638openalex-snapshot

Serum levels of inflammation‐related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers

inferred← citeshttps://doi.org/10.1002/iub.1285openalex-snapshot

Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma

inferred← citeshttps://doi.org/10.1002/jcb.25561openalex-snapshot

The Tyrosine Kinome Dictates Breast Cancer Heterogeneity and Therapeutic Responsiveness

inferred← citeshttps://doi.org/10.1002/jcp.25427openalex-snapshot

Targeting the Breast Cancer Kinome

inferred← citeshttps://doi.org/10.1002/jcp.27246openalex-snapshot

MicroRNAs and breast cancer stem cells: Potential role in breast cancer therapy

inferred← citeshttps://doi.org/10.1002/path.2793openalex-snapshot

Cancer stem cells: problems for therapy?

inferred← citeshttps://doi.org/10.1002/path.4561openalex-snapshot

CBL controls a tyrosine kinase network involving AXL , SYK and LYN in nilotinib‐resistant chronic myeloid leukaemia

inferred← citeshttps://doi.org/10.1002/pmic.202000221openalex-snapshot

Transglutaminase‐2, RNA‐binding proteins and mitochondrial proteins selectively traffic to MDCK cell‐derived microvesicles following H‐Ras‐induced epithelial–mesenchymal transition

inferred← citeshttps://doi.org/10.1002/pros.23871openalex-snapshot

MicroRNA‐139 is a predictor of prostate cancer recurrence and inhibits growth and migration of prostate cancer cells through cell cycle arrest and targeting IGF1R and AXL

inferred← citeshttps://doi.org/10.1002/stem.1045openalex-snapshot

An Endogenous Vitamin K-Dependent Mechanism Regulates Cell Proliferation in the Brain Subventricular Stem Cell Niche

inferred← citeshttps://doi.org/10.1002/stem.2780openalex-snapshot

Epigenetic Silencing of TAP1 in Aldefluor+ Breast Cancer Stem Cells Contributes to Their Enhanced Immune Evasion

inferred← citeshttps://doi.org/10.1002/term.336openalex-snapshot

Efficient in vivo vascularization of tissue-engineering scaffolds

inferred← citeshttps://doi.org/10.1002/vms3.1323openalex-snapshot

Anticancer effect of superoxide dismutase on canine mammary gland tumour in vitro

inferred← citeshttps://doi.org/10.1007/978-1-4419-0717-2_114openalex-snapshot

AXL

inferred← citeshttps://doi.org/10.1007/978-1-4614-6613-0_114-1openalex-snapshot

AXL

inferred← citeshttps://doi.org/10.1007/978-1-4939-6740-7_17openalex-snapshot

In Silico Approach to Identify Potential Inhibitors for Axl-Gas6 Signaling

inferred← citeshttps://doi.org/10.1007/978-3-030-98950-7_11openalex-snapshot

Drivers of EMT and Immune Evasion

inferred← citeshttps://doi.org/10.1007/978-3-030-98950-7_18openalex-snapshot

The Role of AXL Receptor Tyrosine Kinase in Cancer Cell Plasticity and Therapy Resistance

inferred← citeshttps://doi.org/10.1007/978-3-031-93894-8_4openalex-snapshot

Role of Receptor Tyrosine Kinase AXL in Cancer

inferred← citeshttps://doi.org/10.1007/978-3-319-04843-7_3openalex-snapshot

Receptor Tyrosine Kinases in Osteosarcoma: Not Just the Usual Suspects

inferred← citeshttps://doi.org/10.1007/978-3-319-11888-8_2openalex-snapshot

The TAM Receptor Family

inferred← citeshttps://doi.org/10.1007/978-3-319-24223-1_7openalex-snapshot

Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors and Therapeutic Approaches: An Update

inferred← citeshttps://doi.org/10.1007/978-3-319-39147-2_15openalex-snapshot

The Role of Axl Receptor Tyrosine Kinase in Tumor Cell Plasticity and Therapy Resistance

inferred← citeshttps://doi.org/10.1007/978-3-319-39147-2_21openalex-snapshot

The Tumor Microenvironment in Cutaneous Melanoma: Friend or Foe

inferred← citeshttps://doi.org/10.1007/978-3-319-39147-2_9openalex-snapshot

Drivers of EMT and Immune Evasion

inferred← citeshttps://doi.org/10.1007/978-3-319-39406-0_5openalex-snapshot

Axl and Mer Receptor Tyrosine Kinases: Distinct and Nonoverlapping Roles in Inflammation and Cancer?

inferred← citeshttps://doi.org/10.1007/978-3-319-53659-0_3openalex-snapshot

Axl and Its Mediated Signaling Axis in Cancer

inferred← citeshttps://doi.org/10.1007/978-3-319-55947-6_12openalex-snapshot

Mesenchymal-Epithelial Transition and Circulating Tumor Cells in Small Cell Lung Cancer

inferred← citeshttps://doi.org/10.1007/978-94-007-6262-6_17openalex-snapshot

Role of Cancer Stem Cell in Mammary Carcinogenesis and Its Clinical Implication

inferred← citeshttps://doi.org/10.1007/s00018-017-2714-7openalex-snapshot

Signaling pathways and mesenchymal transition in pediatric high-grade glioma

inferred← citeshttps://doi.org/10.1007/s00018-022-04312-3openalex-snapshot

Endocytic trafficking of GAS6–AXL complexes is associated with sustained AKT activation

inferred← citeshttps://doi.org/10.1007/s00044-015-1416-7openalex-snapshot

Molecular modeling study on Mer kinase inhibitors using 3D-QSAR and docking approaches

inferred← citeshttps://doi.org/10.1007/s00262-024-03879-zopenalex-snapshot

Navigating TAM receptor dynamics in tumour immunotherapy

inferred← citeshttps://doi.org/10.1007/s00432-013-1376-6openalex-snapshot

Vimentin as a poor prognostic factor for triple-negative breast cancer

inferred← citeshttps://doi.org/10.1007/s10120-020-01066-4openalex-snapshot

Inhibiting the GAS6/AXL axis suppresses tumor progression by blocking the interaction between cancer-associated fibroblasts and cancer cells in gastric carcinoma

inferred← citeshttps://doi.org/10.1007/s10549-011-1534-yopenalex-snapshot

Prolonged mammosphere culture of MCF-7 cells induces an EMT and repression of the estrogen receptor by microRNAs

inferred← citeshttps://doi.org/10.1007/s10549-011-1690-0openalex-snapshot

Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA

inferred← citeshttps://doi.org/10.1007/s10549-011-1835-1openalex-snapshot

Identification of copy number alterations associated with the progression of DCIS to invasive ductal carcinoma

inferred← citeshttps://doi.org/10.1007/s10555-012-9345-0openalex-snapshot

Cancer stem cells and EMT in carcinoma

inferred← citeshttps://doi.org/10.1007/s10555-013-9483-zopenalex-snapshot

The role of epithelial plasticity in prostate cancer dissemination and treatment resistance

inferred← citeshttps://doi.org/10.1007/s10585-010-9367-3openalex-snapshot

A systems view of epithelial–mesenchymal transition signaling states

inferred← citeshttps://doi.org/10.1007/s10585-013-9566-9openalex-snapshot

In vivo animal models for studying brain metastasis: value and limitations

inferred← citeshttps://doi.org/10.1007/s10585-021-10093-zopenalex-snapshot

Inhibition of the Axl pathway impairs breast and prostate cancer metastasis to the bones and bone remodeling

inferred← citeshttps://doi.org/10.1007/s10637-012-9855-1openalex-snapshot

Mechanisms of acquired resistance to insulin-like growth factor 1 receptor inhibitor in MCF-7 breast cancer cell line

inferred← citeshttps://doi.org/10.1007/s10911-010-9175-zopenalex-snapshot

Epithelial Mesenchymal Transition Traits in Human Breast Cancer Cell Lines Parallel the CD44hi/CD24lo/- Stem Cell Phenotype in Human Breast Cancer

inferred← citeshttps://doi.org/10.1007/s10911-012-9242-8openalex-snapshot

Role of microRNAs in the Regulation of Breast Cancer Stem Cells

inferred← citeshttps://doi.org/10.1007/s11030-014-9556-0openalex-snapshot

3D-QSAR modeling and molecular docking study on Mer kinase inhibitors of pyridine-substituted pyrimidines

inferred← citeshttps://doi.org/10.1007/s11262-021-01882-5openalex-snapshot

Epstein–Barr virus miR-BART4-3p regulates cell proliferation, apoptosis, and migration by targeting AXL in gastric carcinoma

inferred← citeshttps://doi.org/10.1007/s11626-019-00403-xopenalex-snapshot

YKL-40/CHI3L1 facilitates migration and invasion in HER2 overexpressing breast epithelial progenitor cells and generates a niche for capillary-like network formation

inferred← citeshttps://doi.org/10.1007/s11684-018-0656-6openalex-snapshot

Epithelial-to-mesenchymal transition in cancer: complexity and opportunities

inferred← citeshttps://doi.org/10.1007/s11912-017-0579-4openalex-snapshot

Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies

inferred← citeshttps://doi.org/10.1007/s12032-013-0694-5openalex-snapshot

Low expression of long noncoding RNA GAS6-AS1 predicts a poor prognosis in patients with NSCLC

inferred← citeshttps://doi.org/10.1007/s12033-021-00445-1openalex-snapshot

SNHG1/miR-194-5p/MTFR1 Axis Promotes TGFβ1-Induced EMT, Migration and Invasion of Tongue Squamous Cell Carcinoma Cells

inferred← citeshttps://doi.org/10.1007/s12307-011-0083-6openalex-snapshot

Homing of Cancer Cells to the Bone

inferred← citeshttps://doi.org/10.1007/s13277-014-2254-9openalex-snapshot

Phyllodes tumor of the breast: role of Axl and ST6GalNAcII in the development of mammary phyllodes tumors

inferred← citeshttps://doi.org/10.1007/s13402-022-00680-xopenalex-snapshot

Role of ELMO1 in inflammation and cancer—clinical implications

inferred← citeshttps://doi.org/10.1016/b978-0-12-381422-7.10001-xopenalex-snapshot

Molecular Organization of Cells

inferred← citeshttps://doi.org/10.1016/b978-0-12-385942-6.00006-8openalex-snapshot

Molecular Organization of Cells

inferred← citeshttps://doi.org/10.1016/b978-0-12-394447-4.30001-3openalex-snapshot

Receptor Tyrosine Kinases and Their Ligands

inferred← citeshttps://doi.org/10.1016/b978-0-12-398358-9.00008-2openalex-snapshot

Molecular Organization of Cells

inferred← citeshttps://doi.org/10.1016/b978-0-12-804003-4.00011-6openalex-snapshot

Metastatic Cutaneous Squamous Cell Carcinomas

inferred← citeshttps://doi.org/10.1016/b978-0-12-809880-6.00001-1openalex-snapshot

Molecular Organization of Cells

inferred← citeshttps://doi.org/10.1016/b978-0-12-815720-6.00003-4openalex-snapshot

Overexpressed Receptors and Proteins in Lung Cancer

inferred← citeshttps://doi.org/10.1016/b978-0-12-817846-1.00023-0openalex-snapshot

Metastatic cancer: How one can address the therapeutic challenge

inferred← citeshttps://doi.org/10.1016/b978-0-12-817868-3.00008-1openalex-snapshot

TAM family proteins and therapy resistance

inferred← citeshttps://doi.org/10.1016/b978-0-12-818422-6.00006-xopenalex-snapshot

Molecular organization of cells

inferred← citeshttps://doi.org/10.1016/b978-0-12-822833-3.00005-xopenalex-snapshot

Role of epithelial to mesenchymal transition in the resistant mechanism of EGFR-TKIs

inferred← citeshttps://doi.org/10.1016/b978-0-443-42855-5.00010-8openalex-snapshot

The promising role of flavonoids in inhibiting epithelial to mesenchymal transition

inferred← citeshttps://doi.org/10.1016/bs.acr.2020.04.004openalex-snapshot

In vivo modeling of the EGFR family in breast cancer progression and therapeutic approaches

inferred← citeshttps://doi.org/10.1016/bs.ircmb.2020.09.003openalex-snapshot

TAM receptors: A phosphatidylserine receptor family and its implications in viral infections

inferred← citeshttps://doi.org/10.1016/bs.ircmb.2023.10.005openalex-snapshot

Advances in targets in inflammatory breast cancer

inferred← citeshttps://doi.org/10.1016/j.aca.2020.06.060openalex-snapshot

A microfluidic device for differential capture of heterogeneous rare tumor cells with epithelial and mesenchymal phenotypes

inferred← citeshttps://doi.org/10.1016/j.addr.2014.02.009openalex-snapshot

Molecular deconstruction, detection, and computational prediction of microenvironment-modulated cellular responses to cancer therapeutics

inferred← citeshttps://doi.org/10.1016/j.addr.2022.114415openalex-snapshot

Nanotherapeutic treatment of the invasive glioblastoma tumor microenvironment

inferred← citeshttps://doi.org/10.1016/j.anndiagpath.2013.01.005openalex-snapshot

Axl and prostasin are biomarkers for prognosis of ovarian adenocarcinoma

inferred← citeshttps://doi.org/10.1016/j.bbadis.2018.01.020openalex-snapshot

A web platform for the network analysis of high-throughput data in melanoma and its use to investigate mechanisms of resistance to anti-PD1 immunotherapy

inferred← citeshttps://doi.org/10.1016/j.bbamcr.2025.119928openalex-snapshot

AXL kinase inhibitor exhibits antitumor activity by inducing apoptotic cell death in triple-negative breast cancer cells

inferred← citeshttps://doi.org/10.1016/j.bbcan.2018.10.003openalex-snapshot

EMT: A mechanism for escape from EGFR-targeted therapy in lung cancer

inferred← citeshttps://doi.org/10.1016/j.bbcan.2026.189649openalex-snapshot

Redefining first-line standards: The role of next-generation HER2-Targeted therapies in HER2-positive metastatic breast cancer

inferred← citeshttps://doi.org/10.1016/j.bbrc.2013.03.082openalex-snapshot

Gas6 induces cancer cell migration and epithelial–mesenchymal transition through upregulation of MAPK and Slug

inferred← citeshttps://doi.org/10.1016/j.bbrc.2015.01.017openalex-snapshot

Inhibition of Mer and Axl receptor tyrosine kinases leads to increased apoptosis and improved chemosensitivity in human neuroblastoma

inferred← citeshttps://doi.org/10.1016/j.bbrc.2021.05.030openalex-snapshot

Biparatopic single-domain antibodies against Axl achieve ultra-high affinity through intramolecular engagement

inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.151889openalex-snapshot

Vestigial-like family member 1 (VGLL1): An emerging candidate in tumor progression

inferred← citeshttps://doi.org/10.1016/j.bcp.2020.114053openalex-snapshot

A novel small molecule STAT3 inhibitor SLSI-1216 suppresses proliferation and tumor growth of triple-negative breast cancer cells through apoptotic induction

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2013.11.050openalex-snapshot

A microfluidic 3D in vitro model for specificity of breast cancer metastasis to bone

inferred← citeshttps://doi.org/10.1016/j.bioorg.2025.108824openalex-snapshot

Dual inhibition of AXL and MER kinase: scope for lung and breast cancer therapeutics

inferred← citeshttps://doi.org/10.1016/j.biopha.2024.117714openalex-snapshot

RETRACTED: Decoding tumor microenvironment: EMT modulation in breast cancer metastasis and therapeutic resistance, and implications of novel immune checkpoint blockers

inferred← citeshttps://doi.org/10.1016/j.bmcl.2016.12.024openalex-snapshot

Structure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate

inferred← citeshttps://doi.org/10.1016/j.canlet.2012.06.013openalex-snapshot

Epithelial-to-mesenchymal transition and cancer stem(-like) cells in head and neck squamous cell carcinoma

inferred← citeshttps://doi.org/10.1016/j.canlet.2012.08.013openalex-snapshot

An in vivo model of epithelial to mesenchymal transition reveals a mitogenic switch

inferred← citeshttps://doi.org/10.1016/j.canlet.2014.03.036openalex-snapshot

Breast cancer stem cells: Multiple capacities in tumor metastasis

inferred← citeshttps://doi.org/10.1016/j.canlet.2015.05.031openalex-snapshot

Autocrine human growth hormone stimulates the tumor initiating capacity and metastasis of estrogen receptor-negative mammary carcinoma cells

inferred← citeshttps://doi.org/10.1016/j.canlet.2017.06.009openalex-snapshot

lncRNA DANCR promotes tumor progression and cancer stemness features in osteosarcoma by upregulating AXL via miR-33a-5p inhibition

inferred← citeshttps://doi.org/10.1016/j.canlet.2019.05.021openalex-snapshot

Impact of hypoxic tumor microenvironment and tumor cell plasticity on the expression of immune checkpoints

inferred← citeshttps://doi.org/10.1016/j.cell.2016.06.028openalex-snapshot

EMT: 2016

inferred← citeshttps://doi.org/10.1016/j.cellsig.2018.07.010openalex-snapshot

Advances in targeting epidermal growth factor receptor signaling pathway in mammary cancer

inferred← citeshttps://doi.org/10.1016/j.cellsig.2024.111120openalex-snapshot

VGLL1 stabilization of cytoplasmic TAZ promotes EGFR expression and maintains tumor initiating cells in breast cancer independent of TEAD

inferred← citeshttps://doi.org/10.1016/j.celrep.2015.11.025openalex-snapshot

Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization

inferred← citeshttps://doi.org/10.1016/j.celrep.2018.03.114openalex-snapshot

High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia

inferred← citeshttps://doi.org/10.1016/j.celrep.2018.04.019openalex-snapshot

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression

inferred← citeshttps://doi.org/10.1016/j.celrep.2026.117717openalex-snapshot

AXL phosphosite mapping links FAK1 and YAP1 signaling to erlotinib resistance in EGFR-mutant lung cancer

inferred← citeshttps://doi.org/10.1016/j.cels.2015.06.002openalex-snapshot

The AXL Receptor Is a Sensor of Ligand Spatial Heterogeneity

inferred← citeshttps://doi.org/10.1016/j.cels.2019.04.005openalex-snapshot

Simultaneous Integration of Multi-omics Data Improves the Identification of Cancer Driver Modules

inferred← citeshttps://doi.org/10.1016/j.clbc.2016.06.015openalex-snapshot

Impact of Expression of Vimentin and Axl in Breast Cancer

inferred← citeshttps://doi.org/10.1016/j.critrevonc.2015.03.009openalex-snapshot

Biology and immunology of cancer stem(-like) cells in head and neck cancer

inferred← citeshttps://doi.org/10.1016/j.critrevonc.2023.104043openalex-snapshot

Targeting AXL in mesothelioma: From functional characterization to clinical implication

inferred← citeshttps://doi.org/10.1016/j.ctrv.2012.03.003openalex-snapshot

Cancer stem cells: In the line of fire

inferred← citeshttps://doi.org/10.1016/j.ctrv.2023.102639openalex-snapshot

AXL – a new player in resistance to HER2 blockade

inferred← citeshttps://doi.org/10.1016/j.drudis.2020.09.022openalex-snapshot

Therapeutic aspects of the Axl/Gas6 molecular system

inferred← citeshttps://doi.org/10.1016/j.ebiom.2016.01.007openalex-snapshot

Phenotypic Plasticity Determines Cancer Stem Cell Therapeutic Resistance in Oral Squamous Cell Carcinoma

inferred← citeshttps://doi.org/10.1016/j.ebiom.2021.103797openalex-snapshot

Soluble AXL is a novel blood marker for early detection of pancreatic ductal adenocarcinoma and differential diagnosis from chronic pancreatitis

inferred← citeshttps://doi.org/10.1016/j.ejca.2010.10.012openalex-snapshot

S100A14 regulates the invasive potential of oral squamous cell carcinoma derived cell-lines in vitro by modulating expression of matrix metalloproteinases, MMP1 and MMP9

inferred← citeshttps://doi.org/10.1016/j.ejmech.2014.09.085openalex-snapshot

A new goniothalamin N-acylated aza-derivative strongly downregulates mediators of signaling transduction associated with pancreatic cancer aggressiveness

inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.01.065openalex-snapshot

Quinolone antibiotic derivatives as new selective Axl kinase inhibitors

inferred← citeshttps://doi.org/10.1016/j.ejmech.2021.113497openalex-snapshot

Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation

inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.116475openalex-snapshot

Recent discovery and development of AXL inhibitors as antitumor agents

inferred← citeshttps://doi.org/10.1016/j.ejphar.2021.174275openalex-snapshot

Anticancer effects of Traditional Chinese Medicine on epithelial-mesenchymal transition（EMT） in breast cancer: Cellular and molecular targets

inferred← citeshttps://doi.org/10.1016/j.gendis.2021.12.025openalex-snapshot

Decrypting a path based approach for identifying the interplay between PI3K and GSK3 signaling cascade from the perspective of cancer

inferred← citeshttps://doi.org/10.1016/j.gene.2013.03.029openalex-snapshot

Downregulation of Axl in non-MYCN amplified neuroblastoma cell lines reduces migration

inferred← citeshttps://doi.org/10.1016/j.genrep.2025.102209openalex-snapshot

Reduced expression of insulin like growth factor-2 mRNA binding protein 2 (IMP2) elevates TAZ via IMP3 in triple-negative breast cancer

inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e20182openalex-snapshot

Breast cancer stem cells tolerate chromosomal instability during tumor progression via c-Jun/AXL stress signaling

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e35208openalex-snapshot

Competing endogenous RNAs regulatory crosstalk networks: The messages from the RNA world to signaling pathways directing cancer stem cell development

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e37699openalex-snapshot

Boosting immunotherapy efficacy: Empowering the Potency of Dendritic cells loaded with breast cancer lysates through CTLA-4 suppression

inferred← citeshttps://doi.org/10.1016/j.humpath.2015.08.014openalex-snapshot

Coexpression of receptor tyrosine kinase AXL and EGFR in human primary lung adenocarcinomas

inferred← citeshttps://doi.org/10.1016/j.isci.2020.101649openalex-snapshot

AXL Is a Driver of Stemness in Normal Mammary Gland and Breast Cancer

inferred← citeshttps://doi.org/10.1016/j.isci.2023.108395openalex-snapshot

Lupeol synergizes with 5-fluorouracil to combat c-MET/EphA2 mediated chemoresistance in triple negative breast cancer

inferred← citeshttps://doi.org/10.1016/j.isci.2024.109801openalex-snapshot

Phase 1b study of batiraxcept in combination with durvalumab in patients with platinum-resistant ovarian cancer

inferred← citeshttps://doi.org/10.1016/j.isci.2026.117552openalex-snapshot

AXL at the nexus of therapeutic resistance, tumor vascularization, and immune evasion in cancer

inferred← citeshttps://doi.org/10.1016/j.jdermsci.2013.07.001openalex-snapshot

Epithelial to mesenchymal transition markers are associated with an increased metastatic risk in primary cutaneous squamous cell carcinomas but are attenuated in lymph node metastases

inferred← citeshttps://doi.org/10.1016/j.jdermsci.2021.05.002openalex-snapshot

Downregulation of ARMC8 promotes tumorigenesis through activating Wnt/β-catenin pathway and EMT in cutaneous squamous cell carcinomas

inferred← citeshttps://doi.org/10.1016/j.jhep.2015.04.013openalex-snapshot

Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation

inferred← citeshttps://doi.org/10.1016/j.jhep.2015.08.007openalex-snapshot

Loss of NDRG2 promotes epithelial-mesenchymal transition of gallbladder carcinoma cells through MMP-19-mediated Slug expression

inferred← citeshttps://doi.org/10.1016/j.jtho.2016.04.015openalex-snapshot

Axl Receptor Axis: A New Therapeutic Target in Lung Cancer

inferred← citeshttps://doi.org/10.1016/j.jtho.2020.01.015openalex-snapshot

AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells

inferred← citeshttps://doi.org/10.1016/j.lfs.2018.02.033openalex-snapshot

Axl inhibitors as novel cancer therapeutic agents

inferred← citeshttps://doi.org/10.1016/j.mcpro.2026.101574openalex-snapshot

N-Glycosylation of AXL Receptor Tyrosine Kinase Regulates Its Stability, Phosphorylation, and Oncogenic Function

inferred← citeshttps://doi.org/10.1016/j.molcel.2022.01.022openalex-snapshot

RETRACTED: A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells

inferred← citeshttps://doi.org/10.1016/j.neo.2014.03.009openalex-snapshot

Activation of HER3 Interferes with Antitumor Effects of Axl Receptor Tyrosine Kinase Inhibitors: Suggestion of Combination Therapy

inferred← citeshttps://doi.org/10.1016/j.neo.2018.08.005openalex-snapshot

AXL Mediates Esophageal Adenocarcinoma Cell Invasion through Regulation of Extracellular Acidification and Lysosome Trafficking

inferred← citeshttps://doi.org/10.1016/j.omtn.2017.06.023openalex-snapshot

Therapeutic Targeting of AXL Receptor Tyrosine Kinase Inhibits Tumor Growth and Intraperitoneal Metastasis in Ovarian Cancer Models

inferred← citeshttps://doi.org/10.1016/j.oraloncology.2015.04.004openalex-snapshot

Polarization of tumor-associated macrophages and Gas6/Axl signaling in oral squamous cell carcinoma

inferred← citeshttps://doi.org/10.1016/j.redox.2017.02.018openalex-snapshot

The diverse roles of glutathione-associated cell resistance against hypericin photodynamic therapy

inferred← citeshttps://doi.org/10.1016/j.semcancer.2022.12.002openalex-snapshot

Regulation of epithelial-mesenchymal transition by tumor microenvironmental signals and its implication in cancer therapeutics

inferred← citeshttps://doi.org/10.1016/j.tcb.2023.07.006openalex-snapshot

PYK2, a hub of signaling networks in breast cancer progression

inferred← citeshttps://doi.org/10.1016/j.tips.2014.06.006openalex-snapshot

Targeting EMT in cancer: opportunities for pharmacological intervention

inferred← citeshttps://doi.org/10.1016/j.tox.2012.09.017openalex-snapshot

Resveratrol inhibits TGF-β1-induced epithelial-to-mesenchymal transition and suppresses lung cancer invasion and metastasis

inferred← citeshttps://doi.org/10.1016/j.tranon.2020.100773openalex-snapshot

Epithelial-Mesenchymal Transition in Cancer: A Historical Overview

inferred← citeshttps://doi.org/10.1016/j.ydbio.2017.07.025openalex-snapshot

Reprogramming to developmental plasticity in cancer stem cells

inferred← citeshttps://doi.org/10.1016/j.yexcr.2017.03.040openalex-snapshot

Gas6-Axl signaling in presence of Sunitinib is enhanced, diversified and sustained in renal tumor cells, resulting in tumor-progressive advantages

inferred← citeshttps://doi.org/10.1016/j.ygyno.2018.08.008openalex-snapshot

SQ1274, a novel microtubule inhibitor, inhibits ovarian and uterine cancer cell growth

inferred← citeshttps://doi.org/10.1016/s0959-8049(14)50706-xopenalex-snapshot

801: Activation of HER3 interferes with antitumor effects of Axl receptor tyrosine kinase inhibitors − suggestion of combination therapy

inferred← citeshttps://doi.org/10.1021/acs.analchem.2c00297openalex-snapshot

Bioluminescent RAPPID Sensors for the Single-Step Detection of Soluble Axl and Multiplex Analysis of Cell Surface Cancer Biomarkers

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.0c02093openalex-snapshot

Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl Inhibitor

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5b01273openalex-snapshot

AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.6b00608openalex-snapshot

4-Oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as New Axl Kinase Inhibitors

inferred← citeshttps://doi.org/10.1021/acsmedchemlett.4c00511openalex-snapshot

A Hybrid Energy-Based and AI-Based Screening Approach for the Discovery of Novel Inhibitors of AXL

inferred← citeshttps://doi.org/10.1021/acsomega.6c04179openalex-snapshot

Structure-Based Drug Discovery of Triazine Derivatives as Potent and Orally Bioavailable AXL Inhibitors for Cancer Therapy

inferred← citeshttps://doi.org/10.1021/jp403156mopenalex-snapshot

Tristability in Cancer-Associated MicroRNA-TF Chimera Toggle Switch

inferred← citeshttps://doi.org/10.1021/ml200067topenalex-snapshot

Exploring Aigialomycin D and Its Analogues as Protein Kinase Inhibitors for Cancer Targets

inferred← citeshttps://doi.org/10.1021/mp500307topenalex-snapshot

Design, Synthesis, and Validation of Axl-Targeted Monoclonal Antibody Probe for microPET Imaging in Human Lung Cancer Xenograft

inferred← citeshttps://doi.org/10.1038/bjc.2013.9openalex-snapshot

The expression of Axl receptor tyrosine kinase influences the tumour phenotype and clinical outcome of patients with malignant pleural mesothelioma

inferred← citeshttps://doi.org/10.1038/bjc.2014.117openalex-snapshot

CD74: a new prognostic factor for patients with malignant pleural mesothelioma

inferred← citeshttps://doi.org/10.1038/bjc.2015.237openalex-snapshot

Axl receptor tyrosine kinase is a potential therapeutic target in renal cell carcinoma

inferred← citeshttps://doi.org/10.1038/cdd.2014.228openalex-snapshot

LAMC2 enhances the metastatic potential of lung adenocarcinoma

inferred← citeshttps://doi.org/10.1038/cddis.2014.186openalex-snapshot

Axl-altered microRNAs regulate tumorigenicity and gefitinib resistance in lung cancer

inferred← citeshttps://doi.org/10.1038/cddis.2017.113openalex-snapshot

Molecular insights of Gas6/TAM in cancer development and therapy

inferred← citeshttps://doi.org/10.1038/jid.2011.218openalex-snapshot

Human Cutaneous Melanomas Lacking MITF and Melanocyte Differentiation Antigens Express a Functional Axl Receptor Kinase

inferred← citeshttps://doi.org/10.1038/mt.2012.163openalex-snapshot

Targeting Axl With an High-affinity Inhibitory Aptamer

inferred← citeshttps://doi.org/10.1038/nbt0913-775aopenalex-snapshot

First Axl inhibitor enters clinical trials

inferred← citeshttps://doi.org/10.1038/nchembio.1636openalex-snapshot

An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis

inferred← citeshttps://doi.org/10.1038/ncomms10498openalex-snapshot

ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types

inferred← citeshttps://doi.org/10.1038/ncomms6712openalex-snapshot

Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

inferred← citeshttps://doi.org/10.1038/nmeth.4463openalex-snapshot

SCENIC: single-cell regulatory network inference and clustering

inferred← citeshttps://doi.org/10.1038/npjbcancer.2016.33openalex-snapshot

AXL-associated tumor inflammation as a poor prognostic signature in chemotherapy-treated triple-negative breast cancer patients

inferred← citeshttps://doi.org/10.1038/nrc3366openalex-snapshot

Controlling escape from angiogenesis inhibitors

inferred← citeshttps://doi.org/10.1038/nrclinonc.2013.253openalex-snapshot

Molecular analysis of circulating tumour cells—biology and biomarkers

inferred← citeshttps://doi.org/10.1038/nrclinonc.2017.44openalex-snapshot

EMT, CSCs, and drug resistance: the mechanistic link and clinical implications

inferred← citeshttps://doi.org/10.1038/nrd.2015.13openalex-snapshot

Epithelial–mesenchymal transition: a new target in anticancer drug discovery

inferred← citeshttps://doi.org/10.1038/onc.2010.268openalex-snapshot

An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies

inferred← citeshttps://doi.org/10.1038/onc.2010.509openalex-snapshot

Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer

inferred← citeshttps://doi.org/10.1038/onc.2011.544openalex-snapshot

Defining MAP3 kinases required for MDA-MB-231 cell tumor growth and metastasis

inferred← citeshttps://doi.org/10.1038/onc.2011.588openalex-snapshot

Mer receptor tyrosine kinase inhibition impedes glioblastoma multiforme migration and alters cellular morphology

inferred← citeshttps://doi.org/10.1038/onc.2012.355openalex-snapshot

Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer

inferred← citeshttps://doi.org/10.1038/onc.2012.378openalex-snapshot

Profiling phospho-signaling networks in breast cancer using reverse-phase protein arrays

inferred← citeshttps://doi.org/10.1038/onc.2012.89openalex-snapshot

The receptor tyrosine kinase Axl is an essential regulator of prostate cancer proliferation and tumor growth and represents a new therapeutic target

showing the first 200 of 570

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