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Attachment figures activate a safety signal-related neural region and reduce pain experience

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Continuous Emotional Support During Labor in a US Hospital
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Continuous emotional support during labor in a US hospital. A randomized controlled trial
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Influence of social support and emotional context on pain processing and magnetic brain responses in fibromyalgia
inferredcites →https://doi.org/10.1002/hbm.21017openalex-snapshot
Reward and motivation systems: A brain mapping study of early‐stage intense romantic love in Chinese participants
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Psychophysiological and Modulatory Interactions in Neuroimaging
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Affective neuroscience of pleasure: reward in humans and animals
inferredcites →https://doi.org/10.1016/0304-3959(78)90020-9openalex-snapshot
Ratio scales of sensory and affective verbal pain descriptors
inferredcites →https://doi.org/10.1016/0304-3959(85)90026-0openalex-snapshot
A psychophysical analysis of morphine analgesia
inferredcites →https://doi.org/10.1016/0304-3959(88)90023-1openalex-snapshot
A multiple random staircase method of psychophysical pain assessment
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Prefrontal Mechanisms in Extinction of Conditioned Fear
inferredcites →https://doi.org/10.1016/j.biopsych.2006.10.011openalex-snapshot
Recall of Fear Extinction in Humans Activates the Ventromedial Prefrontal Cortex and Hippocampus in Concert
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Deactivation of the Limbic System During Acute Psychosocial Stress: Evidence from Positron Emission Tomography and Functional Magnetic Resonance Imaging Studies
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Extending animal models of fear conditioning to humans
inferredcites →https://doi.org/10.1016/j.conb.2004.10.016openalex-snapshot
Reward representations and reward-related learning in the human brain: insights from neuroimaging
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Human brain mechanisms of pain perception and regulation in health and disease
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The neural correlates of maternal and romantic love
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Brain mediators of cardiovascular responses to social threat
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Brain mediators of cardiovascular responses to social threat, Part II: Prefrontal-subcortical pathways and relationship with anxiety
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Extinction Learning in Humans
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Distinct Neural Signatures for Safety and Danger in the Amygdala and Striatum of the Mouse
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Phobias and preparedness
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Brain mechanisms of pain affect and pain modulation
inferredcites →https://doi.org/10.1037//0022-3514.52.3.511openalex-snapshot
Romantic love conceptualized as an attachment process.
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Social support and recovery from surgery.
inferredcites →https://doi.org/10.1037/0022-3514.52.3.511openalex-snapshot
Romantic love conceptualized as an attachment process.
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Fears, phobias, and preparedness: Toward an evolved module of fear and fear learning.
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Opioid Receptors Regulate the Extinction of Pavlovian Fear Conditioning.
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Neurons in medial prefrontal cortex signal memory for fear extinction
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Human orbitofrontal cortex mediates extinction learning while accessing conditioned representations of value
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The Reward Circuit: Linking Primate Anatomy and Human Imaging
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The human orbitofrontal cortex: linking reward to hedonic experience
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The Nucleus Accumbens is not Critically Involved in Mediating the Effects of a Safety Signal on Behavior
inferredcites →https://doi.org/10.1073/pnas.1009076107openalex-snapshot
Neural activity associated with monitoring the oscillating threat value of a tarantula
inferredcites →https://doi.org/10.1093/brain/awg216openalex-snapshot
Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence
inferredcites →https://doi.org/10.1093/oso/9780195096736.001.0001openalex-snapshot
Affective Neuroscience
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Type I and Type II error concerns in fMRI research: re-balancing the scale
inferredcites →https://doi.org/10.1093/scan/nsq092openalex-snapshot
Neural correlates of long-term intense romantic love
inferredcites →https://doi.org/10.1101/lm.1282309openalex-snapshot
The effect of the μ-opioid receptor antagonist naloxone on extinction of conditioned fear in the developing rat
inferredcites →https://doi.org/10.1111/j.1467-9280.2006.01832.xopenalex-snapshot
Lending a Hand
inferredcites →https://doi.org/10.1111/j.1467-9280.2009.02444.xopenalex-snapshot
A Picture's Worth
inferredcites →https://doi.org/10.1111/j.1469-7793.2000.t01-1-00259.xopenalex-snapshot
Cerebral correlates of autonomic cardiovascular arousal: a functional neuroimaging investigation in humans
inferredcites →https://doi.org/10.1111/j.1743-6109.2010.01999.xopenalex-snapshot
Neuroimaging of Love: fMRI Meta-Analysis Evidence toward New Perspectives in Sexual Medicine
inferredcites →https://doi.org/10.1126/science.288.5472.1769openalex-snapshot
Psychological and Neural Mechanisms of the Affective Dimension of Pain
inferredcites →https://doi.org/10.1152/jn.00838.2004openalex-snapshot
Reward, Motivation, and Emotion Systems Associated With Early-Stage Intense Romantic Love
inferredcites →https://doi.org/10.1177/0956797610368061openalex-snapshot
Of Snakes and Succor
inferredcites →https://doi.org/10.1371/journal.pone.0013309openalex-snapshot
Viewing Pictures of a Romantic Partner Reduces Experimental Pain: Involvement of Neural Reward Systems
inferredcites →https://doi.org/10.1523/jneurosci.0057-10.2010openalex-snapshot
Brain Mediators of Predictive Cue Effects on Perceived Pain
inferredcites →https://doi.org/10.1523/jneurosci.1828-04.2004openalex-snapshot
Opioid Receptors in the Midbrain Periaqueductal Gray Regulate Extinction of Pavlovian Fear Conditioning
inferredcites →https://doi.org/10.1523/jneurosci.2021-06.2006openalex-snapshot
Context-Dependent Human Extinction Memory Is Mediated by a Ventromedial Prefrontal and Hippocampal Network
inferredcites →https://doi.org/10.1523/jneurosci.2265-08.2008openalex-snapshot
From Fear to Safety and Back: Reversal of Fear in the Human Brain
inferredcites →https://doi.org/10.1523/jneurosci.5336-07.2008openalex-snapshot
Blockade of Endogenous Opioid Neurotransmission Enhances Acquisition of Conditioned Fear in Humans
inferredcites →https://doi.org/10.5860/choice.26-4750openalex-snapshot
A secure base: parent-child attachment and healthy human development

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Stress and Reward: A Multimodal Assessment of Resilience after Childhood Sexual Abuse
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Help me if you can: Evaluating the effectiveness of interpersonal compared to intrapersonal emotion regulation in reducing distress
inferred← citeshttps://doi.org/10.1016/j.jesp.2016.04.001openalex-snapshot
Keep in touch: The effects of imagined touch support on stress and exploration
inferred← citeshttps://doi.org/10.1016/j.jpain.2014.06.004openalex-snapshot
Partners' Empathy Increases Pain Ratings: Effects of Perceived Empathy and Attachment Style on Pain Report and Display
inferred← citeshttps://doi.org/10.1016/j.jpain.2016.12.009openalex-snapshot
Experiencing Pain in the Presence of Others: A Structured Experimental Investigation of Older Adults
inferred← citeshttps://doi.org/10.1016/j.jpain.2017.12.007openalex-snapshot
The Social Regulation of Pain: Autonomic and Neurophysiological Changes Associated With Perceived Threat
inferred← citeshttps://doi.org/10.1016/j.jpain.2019.10.007openalex-snapshot
Shared Sensitivity to Physical Pain and Social Evaluation
inferred← citeshttps://doi.org/10.1016/j.jpain.2023.06.012openalex-snapshot
Familiarity From Facial Appearance Leads to Hypoalgesia
inferred← citeshttps://doi.org/10.1016/j.jpain.2024.104599openalex-snapshot
Verbal Support From a Stranger Reduces the Development of Mechanical Hypersensitivity: Behavioral and Neurophysiological Evidence
inferred← citeshttps://doi.org/10.1016/j.jpain.2024.104608openalex-snapshot
Social Determinants and Consequences of Pain: Toward Multilevel, Intersectional, and Life Course Perspectives
inferred← citeshttps://doi.org/10.1016/j.jpain.2024.104619openalex-snapshot
Could Relationship-Based Learnt Beliefs and Expectations Contribute to Physiological Vulnerability of Chronic Pain? Making a Case to Consider Attachment in Pain Research
inferred← citeshttps://doi.org/10.1016/j.jpain.2025.105392openalex-snapshot
The effect of online social support on experimental pain
inferred← citeshttps://doi.org/10.1016/j.jpain.2026.106247openalex-snapshot
Neurophysiological potentials mediating the influence of social support on pain
inferred← citeshttps://doi.org/10.1016/j.jpain.2026.106388openalex-snapshot
The impact of social support cues on pain-related fear and avoidance learning
inferred← citeshttps://doi.org/10.1016/j.jpsychores.2015.10.008openalex-snapshot
Attachment security and pain — The disrupting effect of captivity and PTSS
inferred← citeshttps://doi.org/10.1016/j.jpsychores.2018.01.005openalex-snapshot
Heart rate variability is associated with psychosocial stress in distinct social domains
inferred← citeshttps://doi.org/10.1016/j.jrp.2014.10.003openalex-snapshot
The moderating role of attachment insecurities in the association between social and physical pain
inferred← citeshttps://doi.org/10.1016/j.jveb.2014.06.006openalex-snapshot
The importance of safety signals in animal handling and training
inferred← citeshttps://doi.org/10.1016/j.msard.2022.103643openalex-snapshot
Improving mental health in Multiple Sclerosis with an interpersonal emotion regulation intervention: A prospective, randomized controlled trial
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2018.07.005openalex-snapshot
Investigating the influence of social support on experimental pain and related physiological arousal: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2018.10.014openalex-snapshot
The role of brain reward pathways in stress resilience and health
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2021.09.053openalex-snapshot
Understanding identification-based trust in the light of affiliative bonding: Meta-analytic neuroimaging evidence
inferred← citeshttps://doi.org/10.1016/j.neulet.2017.09.017openalex-snapshot
Capacity and tendency: A neuroscientific framework for the study of emotion regulation
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2014.06.024openalex-snapshot
Ventral medial prefrontal cortex and person evaluation: Forming impressions of others varying in financial and moral status
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2016.04.015openalex-snapshot
How do you make me feel better? Social cognitive emotion regulation and the default mode network
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2019.116053openalex-snapshot
The dorsomedial prefrontal cortex as a flexible hub mediating behavioral as well as local and distributed neural effects of social support context on pain: A Theta Burst Stimulation and TMS-EEG study
inferred← citeshttps://doi.org/10.1016/j.neuropsychologia.2014.07.035openalex-snapshot
Synchronous activation within the default mode network correlates with perceived social support
inferred← citeshttps://doi.org/10.1016/j.neuropsychologia.2024.109003openalex-snapshot
Joyful growth vs. compulsive hedonism: A meta-analysis of brain activation on romantic love and addictive disorders
inferred← citeshttps://doi.org/10.1016/j.nlm.2023.107762openalex-snapshot
Amygdala circuit transitions supporting developmentally-appropriate social behavior
inferred← citeshttps://doi.org/10.1016/j.pec.2012.10.021openalex-snapshot
Patient-centered interviewing is associated with decreased responses to painful stimuli: An initial fMRI study
inferred← citeshttps://doi.org/10.1016/j.physbeh.2021.113490openalex-snapshot
Effects of social support on performance outputs and perceived difficulty during physical exercise
inferred← citeshttps://doi.org/10.1016/j.plrev.2014.09.002openalex-snapshot
Personality from a cognitive-biological perspective
inferred← citeshttps://doi.org/10.1016/j.pnpbp.2018.01.017openalex-snapshot
Evaluating psychosocial contributions to chronic pain outcomes
inferred← citeshttps://doi.org/10.1016/j.pnpbp.2018.08.019openalex-snapshot
How do adolescents regulate distress according to attachment style? A combined eye-tracking and neurophysiological approach
inferred← citeshttps://doi.org/10.1016/j.psyneuen.2015.06.004openalex-snapshot
Thinking of attachments reduces noradrenergic stress response
inferred← citeshttps://doi.org/10.1016/j.psyneuen.2024.107254openalex-snapshot
Share-the-load vs bring-your-own-judge: The effects of friends on social evaluative stress in early adolescence
inferred← citeshttps://doi.org/10.1016/j.psyneuen.2025.107535openalex-snapshot
Value affirmation or emotional support: The buffering effect of social rewards on psychological stress
inferred← citeshttps://doi.org/10.1016/j.psyneuen.2025.107673openalex-snapshot
Consummatory deficits in close social reward predict inflammation-induced depressed mood
inferred← citeshttps://doi.org/10.1016/j.puhe.2021.05.032openalex-snapshot
Developing a framework for arts in health programs targeting individuals with chronic pain: a mixed-methods study of practitioners
inferred← citeshttps://doi.org/10.1016/j.puhe.2025.02.037openalex-snapshot
Associations amongst poverty, loneliness, and a defensive symptom cluster characterised by pain, fatigue, and low mood
inferred← citeshttps://doi.org/10.1016/j.tics.2015.09.003openalex-snapshot
The Social Regulation of Emotion: An Integrative, Cross-Disciplinary Model
inferred← citeshttps://doi.org/10.1016/j.tsc.2023.101366openalex-snapshot
Distinct inter-brain synchronization patterns during group creativity under threats in cooperative and competitive contexts
inferred← citeshttps://doi.org/10.1016/j.ynpai.2023.100122openalex-snapshot
The association of spouse interactions and emotional learning in interference related to chronic back pain
inferred← citeshttps://doi.org/10.1016/j.ynpai.2023.100143openalex-snapshot
Exercise therapy for chronic pain: How does exercise change the limbic brain function?
inferred← citeshttps://doi.org/10.1016/j.ynstr.2022.100498openalex-snapshot
Stress and reward: A multimodal assessment of childhood sexual abuse
inferred← citeshttps://doi.org/10.1017/9781009342919.012openalex-snapshot
Emotion Perception and Elicitation
inferred← citeshttps://doi.org/10.1017/9781009342919.016openalex-snapshot
Pain in the Brain
inferred← citeshttps://doi.org/10.1017/9781009381949.016openalex-snapshot
Relationship Neuroscience
inferred← citeshttps://doi.org/10.1017/9781108264822openalex-snapshot
The Cambridge Handbook of Personality Psychology
inferred← citeshttps://doi.org/10.1017/9781108264822.001openalex-snapshot
Preface
inferred← citeshttps://doi.org/10.1017/9781108264822.002openalex-snapshot
General Introduction
inferred← citeshttps://doi.org/10.1017/9781108264822.004openalex-snapshot
Conceptual and Historical Perspectives
inferred← citeshttps://doi.org/10.1017/9781108264822.005openalex-snapshot
The Trait Approach
inferred← citeshttps://doi.org/10.1017/9781108264822.006openalex-snapshot
Accuracy in Person Perception
inferred← citeshttps://doi.org/10.1017/9781108264822.007openalex-snapshot
States and Situations, Traits and Environments
inferred← citeshttps://doi.org/10.1017/9781108264822.008openalex-snapshot
Personality and the Unconscious
inferred← citeshttps://doi.org/10.1017/9781108264822.009openalex-snapshot
Personality and Emotion
inferred← citeshttps://doi.org/10.1017/9781108264822.011openalex-snapshot
Personality Assessment Methods
inferred← citeshttps://doi.org/10.1017/9781108264822.012openalex-snapshot
Models of Personality Structure
inferred← citeshttps://doi.org/10.1017/9781108264822.013openalex-snapshot
The Five-Factor Model of Personality: Consensus and Controversy
inferred← citeshttps://doi.org/10.1017/9781108264822.014openalex-snapshot
Personality and Intelligence
inferred← citeshttps://doi.org/10.1017/9781108264822.016openalex-snapshot
Temperament and Brain Networks of Attention
inferred← citeshttps://doi.org/10.1017/9781108264822.017openalex-snapshot
Development of Personality across the Life Span
inferred← citeshttps://doi.org/10.1017/9781108264822.018openalex-snapshot
Personality Traits and Mental Disorders
inferred← citeshttps://doi.org/10.1017/9781108264822.019openalex-snapshot
Models of Physical Health and Personality
inferred← citeshttps://doi.org/10.1017/9781108264822.020openalex-snapshot
Attachment Theory
inferred← citeshttps://doi.org/10.1017/9781108264822.022openalex-snapshot
Evolutionary Personality Psychology
inferred← citeshttps://doi.org/10.1017/9781108264822.023openalex-snapshot
Personality in Nonhuman Animals
inferred← citeshttps://doi.org/10.1017/9781108264822.024openalex-snapshot
Genetics of Personality
inferred← citeshttps://doi.org/10.1017/9781108264822.025openalex-snapshot
Approach–Avoidance Theories of Personality
inferred← citeshttps://doi.org/10.1017/9781108264822.026openalex-snapshot
Personality Neuroscience
inferred← citeshttps://doi.org/10.1017/9781108264822.028openalex-snapshot
Cognitive Processes and Models
inferred← citeshttps://doi.org/10.1017/9781108264822.029openalex-snapshot
Self-Regulation and Control in Personality Functioning
inferred← citeshttps://doi.org/10.1017/9781108264822.030openalex-snapshot
Basic Needs, Goals and Motivation
inferred← citeshttps://doi.org/10.1017/9781108264822.031openalex-snapshot
Personality and the Self
inferred← citeshttps://doi.org/10.1017/9781108264822.032openalex-snapshot
Traits and Dynamic Processes
inferred← citeshttps://doi.org/10.1017/9781108264822.033openalex-snapshot
Anxiety, Depression and Cognitive Dysfunction
inferred← citeshttps://doi.org/10.1017/9781108264822.035openalex-snapshot
Narrative Identity in the Social World
inferred← citeshttps://doi.org/10.1017/9781108264822.036openalex-snapshot
Social Relations and Social Support
inferred← citeshttps://doi.org/10.1017/9781108264822.037openalex-snapshot
Personality in Cross-Cultural Perspective
inferred← citeshttps://doi.org/10.1017/9781108264822.038openalex-snapshot
Personality and Politics
inferred← citeshttps://doi.org/10.1017/9781108264822.040openalex-snapshot
Personality at Work
inferred← citeshttps://doi.org/10.1017/9781108264822.041openalex-snapshot
Educational Psychology
inferred← citeshttps://doi.org/10.1017/9781108264822.042openalex-snapshot
Personality in Clinical Psychology
inferred← citeshttps://doi.org/10.1017/9781108264822.043openalex-snapshot
Personality and Crime
inferred← citeshttps://doi.org/10.1017/9781108264822.044openalex-snapshot
Personality, Preferences and Socioeconomic Behavior
inferred← citeshttps://doi.org/10.1017/9781108264822.045openalex-snapshot
Addendum: Statistical Analyses and Computer Programming in Personality
inferred← citeshttps://doi.org/10.1017/9781108264822.046openalex-snapshot
Index
inferred← citeshttps://doi.org/10.1017/cts.2022.392openalex-snapshot
The transition from in-person to virtual museum programing for individuals living with chronic pain – A formative evaluation
inferred← citeshttps://doi.org/10.1017/s0954579413000692openalex-snapshot
Contributions of attachment theory and research: A framework for future research, translation, and policy
inferred← citeshttps://doi.org/10.1017/s0954579417001705openalex-snapshot
Attachment security moderates the link between adverse childhood experiences and cellular aging
inferred← citeshttps://doi.org/10.1017/s0954579424000841openalex-snapshot
The extraordinary “ordinary magic” of resilience
inferred← citeshttps://doi.org/10.1017/sjp.2017.56openalex-snapshot
Post-Traumatic Stress Disorder Symptomatology in People affected by Home Eviction in Spain
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