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Redesign of a cross-reactive antibody to dengue virus with broad-spectrum activity and increased in vivo potency

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/prot.10389openalex-snapshot

ZDOCK: An initial‐stage protein‐docking algorithm

inferredcites →https://doi.org/10.1002/prot.21373openalex-snapshot

ZRANK: Reranking protein docking predictions with an optimized energy function

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Identification of near‐native structures by clustering protein docking conformations

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An automated decision‐tree approach to predicting protein interaction hot spots

inferredcites →https://doi.org/10.1002/prot.22764openalex-snapshot

Performance of ZDOCK and ZRANK in CAPRI rounds 13–19

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Affinity Measurements by Competition ELISA

inferredcites →https://doi.org/10.1016/0022-1759(85)90044-4openalex-snapshot

Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay

inferredcites →https://doi.org/10.1016/j.bbapap.2011.12.007openalex-snapshot

Antigen–antibody interface properties: Composition, residue interactions, and features of 53 non-redundant structures

inferredcites →https://doi.org/10.1016/j.bmcl.2009.05.005openalex-snapshot

Improving the species cross-reactivity of an antibody using computational design

inferredcites →https://doi.org/10.1016/j.chom.2010.08.007openalex-snapshot

The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity

inferredcites →https://doi.org/10.1016/j.jmb.2005.03.041openalex-snapshot

Molecular Recognition by a Binary Code

inferredcites →https://doi.org/10.1016/j.jmb.2009.12.053openalex-snapshot

Rapid Structural Characterization of Human Antibody–Antigen Complexes through Experimentally Validated Computational Docking

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Community-Wide Assessment of Protein-Interface Modeling Suggests Improvements to Design Methodology

inferredcites →https://doi.org/10.1016/j.str.2012.01.001openalex-snapshot

Mechanism of Dengue Virus Broad Cross-Neutralization by a Monoclonal Antibody

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Basic Local Alignment Search Tool

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Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial

inferredcites →https://doi.org/10.1016/s0165-022x(03)00145-3openalex-snapshot

Determination of antibody affinity by ELISA. Theory

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Designing and optimizing library selection strategies for generating high-affinity antibodies

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A recombinant Fab neutralizes dengue virus in vitro

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Strategies for selection of antibodies by phage display

inferredcites →https://doi.org/10.1016/s1286-4579(00)01258-2openalex-snapshot

Dengue viral infections; pathogenesisand epidemiology

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Redesigning an Antibody Fragment for Faster Association with Its Antigen

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Rational design of faster associating and tighter binding protein complexes.

inferredcites →https://doi.org/10.1038/nbt1336openalex-snapshot

Computational design of antibody-affinity improvement beyond in vivo maturation

inferredcites →https://doi.org/10.1038/nri1837openalex-snapshot

Potent antibody therapeutics by design

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Prospects for a dengue virus vaccine

inferredcites →https://doi.org/10.1038/nrmicro2460openalex-snapshot

Dengue: a continuing global threat

inferredcites →https://doi.org/10.1038/nsb0596-427openalex-snapshot

Rapid, electrostatically assisted association of proteins

inferredcites →https://doi.org/10.1038/nsmb.1382openalex-snapshot

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins

inferredcites →https://doi.org/10.1073/pnas.0401786101openalex-snapshot

Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition

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Affinity maturation of antibodies assisted by in silico modeling

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Principles of protein-protein interactions.

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Relationship of Preexisting Dengue Virus (DV) Neutralizing Antibody Levels to Viremia and Severity of Disease in a Prospective Cohort Study of DV Infection in Thailand

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Dengue Virus (DV) Enhancing Antibody Activity in Preillness Plasma Does Not Predict Subsequent Disease Severity or Viremia in Secondary DV Infection

inferredcites →https://doi.org/10.1093/bioinformatics/btg371openalex-snapshot

ClusPro: an automated docking and discrimination method for the prediction of protein complexes

inferredcites →https://doi.org/10.1093/protein/gzs024openalex-snapshot

Computer-aided antibody design

inferredcites →https://doi.org/10.1097/qco.0b013e32834a1b0bopenalex-snapshot

Critical issues in dengue vaccine development

inferredcites →https://doi.org/10.1099/0022-1317-82-8-1885openalex-snapshot

Mapping of a dengue virus neutralizing epitope critical for the infectivity of all serotypes: insight into the neutralization mechanism

inferredcites →https://doi.org/10.1099/vir.0.83028-0openalex-snapshot

Mapping to completeness and transplantation of a group-specific, discontinuous, neutralizing epitope in the envelope protein of dengue virus

inferredcites →https://doi.org/10.1110/ps.052030506openalex-snapshot

Affinity enhancement of an in vivo matured therapeutic antibody using structure‐based computational design

inferredcites →https://doi.org/10.1111/j.1742-4658.2005.05045.xopenalex-snapshot

Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus

inferredcites →https://doi.org/10.1126/science.1205669openalex-snapshot

A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins

inferredcites →https://doi.org/10.1128/jvi.00316-08openalex-snapshot

Antibodies to Envelope Glycoprotein of Dengue Virus during the Natural Course of Infection Are Predominantly Cross-Reactive and Recognize Epitopes Containing Highly Conserved Residues at the Fusion Loop of Domain II

inferredcites →https://doi.org/10.1128/jvi.69.8.4792-4796.1995openalex-snapshot

Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors

inferredcites →https://doi.org/10.1128/jvi.73.1.783-786.1999openalex-snapshot

New Mouse Model for Dengue Virus Vaccine Testing

inferredcites →https://doi.org/10.1136/pgmj.2004.019638openalex-snapshot

Dengue viral infections

inferredcites →https://doi.org/10.1146/annurev-immunol-031210-101315openalex-snapshot

Immune Response to Dengue Virus and Prospects for a Vaccine

inferredcites →https://doi.org/10.1146/annurev.micro.62.081307.163005openalex-snapshot

Global Spread and Persistence of Dengue

inferredcites →https://doi.org/10.2149/tmh.2010-21openalex-snapshot

An Updated Loop-Mediated Isothermal Amplification Method for Rapid Diagnosis of H5N1 Avian Influenza Viruses

inferredcites →https://doi.org/10.2149/tmh.2011-s05openalex-snapshot

Dengue, Urbanization and Globalization: The Unholy Trinity of the 21st Century

inferredcites →https://doi.org/10.2174/1381612053382106openalex-snapshot

Docking: Successes and Challenges

inferredcites →https://doi.org/10.3390/ijms12010226openalex-snapshot

Computational Docking of Antibody-Antigen Complexes, Opportunities and Pitfalls Illustrated by Influenza Hemagglutinin

inferredcites →https://doi.org/10.3390/v3122374openalex-snapshot

The Human Antibody Response to Dengue Virus Infection

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Safety and Preliminary Efficacy of Dengue Monoclonal Antibody in Adult Patients

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The validation of artificial anti‐monkeypox antibodies by in silico and experimental approaches

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Feature Design for Protein Interface Hotspots Using KFC2 and Rosetta

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Chimeric protein probes for C5a receptors through fusion of the anaphylatoxin C5a core region with a small-molecule antagonist

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Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope

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Molecular dynamics simulations and Gaussian network model for designing antibody mimicking protein towards dengue envelope protein

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Structural and Functional Characterization of a Cross-Reactive Dengue Virus Neutralizing Antibody that Recognizes a Cryptic Epitope

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A complex between the Zika virion and the Fab of a broadly cross-reactive neutralizing monoclonal antibody revealed by cryo-EM and single particle analysis at 4.1 Å resolution

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An Engineered N-Glycosylated Dengue Envelope Protein Domain III Facilitates Epitope-Directed Selection of Potently Neutralizing and Minimally Enhancing Antibodies

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Potent Cross-Serotype Dengue Neutralization with Low ADE by AG-Strand-Targeting Anti-EDIII Antibodies

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Temperature-dependent folding allows stable dimerization of secretory and virus-associated E proteins of Dengue and Zika viruses in mammalian cells

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