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Notch signaling regulates cardiomyocyte proliferation during zebrafish heart regeneration

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1 of the 49 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-21): 10.1073/pnas.0808357105 (notice 2019-09-30).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.cell.2006.08.052openalex-snapshot

A Dynamic Epicardial Injury Response Supports Progenitor Cell Activity during Zebrafish Heart Regeneration

inferredcites →https://doi.org/10.1016/j.devcel.2006.12.011openalex-snapshot

Notch Signaling Is Essential for Ventricular Chamber Development

inferredcites →https://doi.org/10.1016/j.devcel.2011.01.010openalex-snapshot

Retinoic Acid Production by Endocardium and Epicardium Is an Injury Response Essential for Zebrafish Heart Regeneration

inferredcites →https://doi.org/10.1016/j.devcel.2012.01.014openalex-snapshot

Coordinating Tissue Interactions: Notch Signaling in Cardiac Development and Disease

inferredcites →https://doi.org/10.1016/j.ydbio.2012.07.007openalex-snapshot

Pan-epicardial lineage tracing reveals that epicardium derived cells give rise to myofibroblasts and perivascular cells during zebrafish heart regeneration

inferredcites →https://doi.org/10.1016/s0925-4773(98)00209-3openalex-snapshot

Use of the Gal4-UAS technique for targeted gene expression in the zebrafish

inferredcites →https://doi.org/10.1016/s1050-1738(03)00082-3openalex-snapshot

Hey Genes in Cardiovascular Development

inferredcites →https://doi.org/10.1016/s1534-5807(02)00409-4openalex-snapshot

Mind Bomb Is a Ubiquitin Ligase that Is Essential for Efficient Activation of Notch Signaling by Delta

inferredcites →https://doi.org/10.1038/35102599openalex-snapshot

Gridlock signalling pathway fashions the first embryonic artery

inferredcites →https://doi.org/10.1038/nature08804openalex-snapshot

Primary contribution to zebrafish heart regeneration by gata4+ cardiomyocytes

inferredcites →https://doi.org/10.1038/nature08899openalex-snapshot

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

inferredcites →https://doi.org/10.1038/nature10147openalex-snapshot

Heart regeneration

inferredcites →https://doi.org/10.1038/nature11682openalex-snapshot

Mammalian heart renewal by pre-existing cardiomyocytes

inferredcites →https://doi.org/10.1038/nature12054openalex-snapshot

Meis1 regulates postnatal cardiomyocyte cell cycle arrest

inferredcites →https://doi.org/10.1038/nature12322openalex-snapshot

In vivo cardiac reprogramming contributes to zebrafish heart regeneration

inferredcites →https://doi.org/10.1038/nprot.2012.025openalex-snapshot

Cryoinjury as a myocardial infarction model for the study of cardiac regeneration in the zebrafish

inferredcites →https://doi.org/10.1073/pnas.0808357105openalex-snapshot

RETRACTED: Notch1 regulates the fate of cardiac progenitor cells

inferredcites →https://doi.org/10.1073/pnas.0915016107openalex-snapshot

PDGF signaling is required for epicardial function and blood vessel formation in regenerating zebrafish hearts

inferredcites →https://doi.org/10.1073/pnas.1208863110openalex-snapshot

Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family

inferredcites →https://doi.org/10.1073/pnas.1834204100openalex-snapshot

Activation of Notch signaling pathway precedes heart regeneration in zebrafish

inferredcites →https://doi.org/10.1083/jcb.200806091openalex-snapshot

Notch1 signaling stimulates proliferation of immature cardiomyocytes

inferredcites →https://doi.org/10.1083/jcb.200806104openalex-snapshot

Notch activates cell cycle reentry and progression in quiescent cardiomyocytes

inferredcites →https://doi.org/10.1084/jem.20081427openalex-snapshot

Control of the adaptive response of the heart to stress via the Notch1 receptor pathway

inferredcites →https://doi.org/10.1093/eurheartj/ehs269openalex-snapshot

The Notch pathway controls fibrotic and regenerative repair in the adult heart

inferredcites →https://doi.org/10.1101/gad.1629408openalex-snapshot

Foxn4 directly regulates tbx2b expression and atrioventricular canal formation

inferredcites →https://doi.org/10.1126/science.1077857openalex-snapshot

Heart Regeneration in Zebrafish

inferredcites →https://doi.org/10.1126/science.1164680openalex-snapshot

Evidence for Cardiomyocyte Renewal in Humans

inferredcites →https://doi.org/10.1126/science.1200708openalex-snapshot

Transient Regenerative Potential of the Neonatal Mouse Heart

inferredcites →https://doi.org/10.1128/mcb.23.2.655-664.2003openalex-snapshot

Growth Suppression of Pre-T Acute Lymphoblastic Leukemia Cells by Inhibition of Notch Signaling

inferredcites →https://doi.org/10.1161/cir.0b013e31828124adopenalex-snapshot

Heart Disease and Stroke Statistics—2013 Update

inferredcites →https://doi.org/10.1161/circresaha.107.164749openalex-snapshot

Activation of Notch-Mediated Protective Signaling in the Myocardium

inferredcites →https://doi.org/10.1161/circresaha.109.203034openalex-snapshot

Distinct Roles for Cell-Autonomous Notch Signaling in Cardiomyocytes of the Embryonic and Adult Heart

inferredcites →https://doi.org/10.1161/circresaha.110.233262openalex-snapshot

A Dynamic Notch Injury Response Activates Epicardium and Contributes to Fibrosis Repair

inferredcites →https://doi.org/10.1161/circresaha.111.259598openalex-snapshot

Cardiomyocyte Renewal in Humans

inferredcites →https://doi.org/10.1161/circulationaha.112.155911openalex-snapshot

The “Heart Disease and Stroke Statistics—2013 Update” and the Need for a National Cardiovascular Surveillance System

inferredcites →https://doi.org/10.1186/1471-213x-11-21openalex-snapshot

The zebrafish heart regenerates after cryoinjury-induced myocardial infarction

inferredcites →https://doi.org/10.1242/dev.059345openalex-snapshot

Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish

inferredcites →https://doi.org/10.1242/dev.060897openalex-snapshot

Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish

inferredcites →https://doi.org/10.1242/dev.067041openalex-snapshot

tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration

inferredcites →https://doi.org/10.1242/dev.068601openalex-snapshot

The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion

inferredcites →https://doi.org/10.1242/dev.078543openalex-snapshot

The regenerative capacity of the zebrafish heart is dependent on TGFβ signaling

inferredcites →https://doi.org/10.1242/dev.088526openalex-snapshot

In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration

inferredcites →https://doi.org/10.1242/dev.123.1.205openalex-snapshot

Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio

inferredcites →https://doi.org/10.1242/dev.126.9.1811openalex-snapshot

her4 , a zebrafish homologue of the Drosophila neurogenic gene E(spl) , is a target of NOTCH signalling

inferredcites →https://doi.org/10.1242/dev.128.7.1099openalex-snapshot

An instructive function for Notch in promoting gliogenesis in the zebrafish retina

inferredcites →https://doi.org/10.1371/journal.pone.0018503openalex-snapshot

Regeneration of Cryoinjury Induced Necrotic Heart Lesions in Zebrafish Is Associated with Epicardial Activation and Cardiomyocyte Proliferation

inferredcites →https://doi.org/10.1371/journal.pone.0053748openalex-snapshot

Hypoxia/Reoxygenation Cardiac Injury and Regeneration in Zebrafish Adult Heart

inferredcites →https://doi.org/10.3109/14017431.2010.511256openalex-snapshot

Activation of Notch signaling in cardiomyocytes during post-infarction remodeling

inferredcites →https://doi.org/10.3791/3666openalex-snapshot

Induction of Myocardial Infarction in Adult Zebrafish Using Cryoinjury

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3904965openalex-extracted

Macrophages Stimulate Epicardial vegfaa Expression to Trigger Cardiomyocyte Proliferation in Larval Zebrafish Heart Regeneration

inferred← citeshttps://doi.org/10.1002/9780470015902.a0022101.pub2openalex-snapshot

Regeneration of Organs and Appendages in Zebrafish: A Window into Underlying Control Mechanisms

inferred← citeshttps://doi.org/10.1002/9783527692156.ch60openalex-snapshot

The Inflammatory Response in Tissue Repair

inferred← citeshttps://doi.org/10.1002/ar.24028openalex-snapshot

Proepicardium: Current Understanding of its Structure, Induction, and Fate

inferred← citeshttps://doi.org/10.1002/cne.24489openalex-snapshot

Involvement of sonic hedgehog and notch signaling in regenerative neurogenesis in adult zebrafish optic tectum after stab injury

inferred← citeshttps://doi.org/10.1002/dvdy.229openalex-snapshot

Notch and Bmp signaling pathways act coordinately during the formation of the proepicardium

inferred← citeshttps://doi.org/10.1002/dvdy.24411openalex-snapshot

Cell migration during heart regeneration in zebrafish

inferred← citeshttps://doi.org/10.1002/dvdy.305openalex-snapshot

Zebrafish heart regenerates after chemoptogenetic cardiomyocyte depletion

inferred← citeshttps://doi.org/10.1002/glia.24075openalex-snapshot

Notch signaling via Hey1 and Id2b regulates Müller glia's regenerative response to retinal injury

inferred← citeshttps://doi.org/10.1002/iid3.70282openalex-snapshot

Role of Macrophages in Cardiac Remodeling: Cues From Zebrafish Heart

inferred← citeshttps://doi.org/10.1002/jcp.31060openalex-snapshot

The origin, progress, and application of cell‐based cardiac regeneration therapy

inferred← citeshttps://doi.org/10.1002/mco2.70407openalex-snapshot

Heart Regeneration and Repair: Molecular Mechanism and Therapeutic Targets

inferred← citeshttps://doi.org/10.1002/reg2.83openalex-snapshot

Zebrafish heart regeneration: 15 years of discoveries

inferred← citeshttps://doi.org/10.1002/wdev.321openalex-snapshot

Wound‐induced cell proliferation during animal regeneration

inferred← citeshttps://doi.org/10.1007/978-1-0716-2217-9_22openalex-snapshot

Modulation of VEGFA Signaling During Heart Regeneration in Zebrafish

inferred← citeshttps://doi.org/10.1007/978-3-030-23459-1_12openalex-snapshot

Cellular and Molecular Mechanisms of Hydra Regeneration

inferred← citeshttps://doi.org/10.1007/978-3-319-05392-9_135openalex-snapshot

Zebrafish

inferred← citeshttps://doi.org/10.1007/978-3-319-19387-8_68openalex-snapshot

Proliferation of cardiomyocytes in young infants, future implication in human heart regeneration

inferred← citeshttps://doi.org/10.1007/978-3-319-25427-2_11openalex-snapshot

Stem Cell Therapies for Cardiac Regeneration: Current Burden—Future Directions

inferred← citeshttps://doi.org/10.1007/978-3-319-25427-2_7openalex-snapshot

Epigenetic Regulation of Cardiac Regeneration

inferred← citeshttps://doi.org/10.1007/978-3-319-27583-3_10openalex-snapshot

Cardiac Regeneration in Zebrafish

inferred← citeshttps://doi.org/10.1007/978-3-642-27728-3_135-1openalex-snapshot

Zebrafish

inferred← citeshttps://doi.org/10.1007/978-3-662-56179-9_10openalex-snapshot

Dedifferentiation and Organ Regeneration

inferred← citeshttps://doi.org/10.1007/978-981-16-5217-2_10openalex-snapshot

Zebrafish Model and Cardiovascular System for Novel Therapies

inferred← citeshttps://doi.org/10.1007/s00395-020-0816-0openalex-snapshot

Non-coding RNAs: emerging players in cardiomyocyte proliferation and cardiac regeneration

inferred← citeshttps://doi.org/10.1007/s00395-021-00858-8openalex-snapshot

miR-106a–363 cluster in extracellular vesicles promotes endogenous myocardial repair via Notch3 pathway in ischemic heart injury

inferred← citeshttps://doi.org/10.1007/s00395-024-01049-xopenalex-snapshot

Targeting cardiomyocyte cell cycle regulation in heart failure

inferred← citeshttps://doi.org/10.1007/s10456-020-09761-7openalex-snapshot

To be or not to be: endothelial cell plasticity in development, repair, and disease

inferred← citeshttps://doi.org/10.1007/s10529-017-2327-0openalex-snapshot

MAPK/ERK signalling is required for zebrafish cardiac regeneration

inferred← citeshttps://doi.org/10.1007/s10741-016-9579-yopenalex-snapshot

Zebrafish models of cardiovascular disease

inferred← citeshttps://doi.org/10.1007/s11248-018-0098-6openalex-snapshot

Generation and characterization of a zebrafish muscle specific inducible Cre line

inferred← citeshttps://doi.org/10.1007/s11427-015-4838-zopenalex-snapshot

Using zebrafish as the model organism to understand organ regeneration

inferred← citeshttps://doi.org/10.1007/s11427-020-1915-yopenalex-snapshot

Biodiversity-based development and evolution: the emerging research systems in model and non-model organisms

inferred← citeshttps://doi.org/10.1007/s11886-021-01510-6openalex-snapshot

Mechanisms Underlying Cardiomyocyte Development: Can We Exploit Them to Regenerate the Heart?

inferred← citeshttps://doi.org/10.1007/s11886-024-02162-yopenalex-snapshot

Cardiac Regeneration in Adult Zebrafish: A Review of Signaling and Metabolic Coordination

inferred← citeshttps://doi.org/10.1007/s13238-020-00695-wopenalex-snapshot

Primary cilia mediate Klf2-dependant Notch activation in regenerating heart

inferred← citeshttps://doi.org/10.1007/s40139-015-0063-5openalex-snapshot

Dedifferentiation, Transdifferentiation, and Proliferation: Mechanisms Underlying Cardiac Muscle Regeneration in Zebrafish

inferred← citeshttps://doi.org/10.1007/s42995-023-00202-0openalex-snapshot

Comparative analysis of the cardiac structure and transcriptome of scallop and snail, perspectives on heart chamber evolution

inferred← citeshttps://doi.org/10.1016/b978-0-12-812431-4.00051-8openalex-snapshot

Zebrafish as a Platform for Drug Screening

inferred← citeshttps://doi.org/10.1016/b978-0-323-99570-2.00022-9openalex-snapshot

Notch signaling molecules

inferred← citeshttps://doi.org/10.1016/bs.fp.2017.09.004openalex-snapshot

Cardiac Preconditioning, Remodeling and Regeneration

inferred← citeshttps://doi.org/10.1016/bs.ircmb.2016.04.002openalex-snapshot

Endogenous Mechanisms of Cardiac Regeneration

inferred← citeshttps://doi.org/10.1016/bs.mcb.2016.01.009openalex-snapshot

Contemporary zebrafish transgenesis with Tol2 and application for Cre/lox recombination experiments

inferred← citeshttps://doi.org/10.1016/j.addr.2016.04.023openalex-snapshot

Stem cell-based therapy: Improving myocardial cell delivery

inferred← citeshttps://doi.org/10.1016/j.arr.2016.06.004openalex-snapshot

The emerging role of Notch pathway in ageing: Focus on the related mechanisms in age-related diseases

inferred← citeshttps://doi.org/10.1016/j.bbagrm.2014.07.021openalex-snapshot

The link between injury-induced stress and regenerative phenomena: A cellular and genetic synopsis

inferred← citeshttps://doi.org/10.1016/j.bbrc.2014.12.017openalex-snapshot

Tissue factor pathway inhibitor-2 is critical in zebrafish cardiogenesis

inferred← citeshttps://doi.org/10.1016/j.bbrc.2021.08.094openalex-snapshot

Noncanonical Notch signals have opposing roles during cardiac development

inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.152163openalex-snapshot

Vegfa signaling ameliorates cardiac fibrosis and restores endothelial regeneration in a point-mutated zebrafish model of pseudoxanthoma elasticum

inferred← citeshttps://doi.org/10.1016/j.biocel.2017.11.015openalex-snapshot

Glycerophosphodiesterase GDE2/GDPD5 affects pancreas differentiation in zebrafish

inferred← citeshttps://doi.org/10.1016/j.cdev.2021.203715openalex-snapshot

Notch signaling mediates olfactory multiciliated cell specification

inferred← citeshttps://doi.org/10.1016/j.cell.2018.12.023openalex-snapshot

A Unique Collateral Artery Development Program Promotes Neonatal Heart Regeneration

inferred← citeshttps://doi.org/10.1016/j.celrep.2018.12.048openalex-snapshot

Endocardial Notch Signaling Promotes Cardiomyocyte Proliferation in the Regenerating Zebrafish Heart through Wnt Pathway Antagonism

inferred← citeshttps://doi.org/10.1016/j.celrep.2019.01.061openalex-snapshot

Germline Stem Cells Drive Ovary Regeneration in Zebrafish

inferred← citeshttps://doi.org/10.1016/j.celrep.2026.117249openalex-snapshot

Time-resolved single-cell transcriptomics maps zebrafish heart development

inferred← citeshttps://doi.org/10.1016/j.celrep.2026.118050openalex-snapshot

A Gata4–Loxl2 axis controls ECM remodeling to enable scar-free spinal cord regeneration in zebrafish

inferred← citeshttps://doi.org/10.1016/j.cophys.2019.12.016openalex-snapshot

Talkin’ ‘bout regeneration: new advances in cardiac regeneration using the zebrafish

inferred← citeshttps://doi.org/10.1016/j.cophys.2020.02.002openalex-snapshot

Signals for cardiomyocyte proliferation during zebrafish heart regeneration

inferred← citeshttps://doi.org/10.1016/j.cr.2018.11.002openalex-snapshot

Molecular switch model for cardiomyocyte proliferation

inferred← citeshttps://doi.org/10.1016/j.devcel.2015.04.001openalex-snapshot

Chemokine-Guided Angiogenesis Directs Coronary Vasculature Formation in Zebrafish

inferred← citeshttps://doi.org/10.1016/j.devcel.2019.10.019openalex-snapshot

Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation

inferred← citeshttps://doi.org/10.1016/j.devcel.2021.09.005openalex-snapshot

Acute brain vascular regeneration occurs via lymphatic transdifferentiation

inferred← citeshttps://doi.org/10.1016/j.devcel.2022.05.014openalex-snapshot

Macrophages trigger cardiomyocyte proliferation by increasing epicardial vegfaa expression during larval zebrafish heart regeneration

inferred← citeshttps://doi.org/10.1016/j.drudis.2015.02.010openalex-snapshot

How to mend a broken heart: adult and induced pluripotent stem cell therapy for heart repair and regeneration

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2023.115112openalex-snapshot

Exposure to environmental concentrations of glyphosate induces cardiotoxicity through cellular senescence and reduced cell proliferation capacity

inferred← citeshttps://doi.org/10.1016/j.fmre.2021.11.025openalex-snapshot

Continuous live imaging reveals a subtle pathological alteration with cell behaviors in congenital heart malformation

inferred← citeshttps://doi.org/10.1016/j.gde.2016.05.011openalex-snapshot

Zebrafish fin and heart: what's special about regeneration?

inferred← citeshttps://doi.org/10.1016/j.gde.2016.05.029openalex-snapshot

Myocardial plasticity: cardiac development, regeneration and disease

inferred← citeshttps://doi.org/10.1016/j.gde.2020.05.020openalex-snapshot

Recent insights into zebrafish cardiac regeneration

inferred← citeshttps://doi.org/10.1016/j.gendis.2023.01.031openalex-snapshot

Cardiac regeneration: Pre-existing cardiomyocyte as the hub of novel signaling pathway

inferred← citeshttps://doi.org/10.1016/j.gene.2022.146242openalex-snapshot

Reconstruction of regulatory network predicts transcription factors driving the dynamics of zebrafish heart regeneration

inferred← citeshttps://doi.org/10.1016/j.isci.2019.04.009openalex-snapshot

RETRACTED: Modulation of TNFα Activity by the microRNA Let-7 Coordinates Zebrafish Heart Regeneration

inferred← citeshttps://doi.org/10.1016/j.jgg.2014.12.002openalex-snapshot

Regeneration across Metazoan Phylogeny: Lessons from Model Organisms

inferred← citeshttps://doi.org/10.1016/j.jgg.2021.12.002openalex-snapshot

Zebrafish Foxc1a controls ventricular chamber maturation by directly regulating wwtr1 and nkx2.5 expression

inferred← citeshttps://doi.org/10.1016/j.jgg.2022.04.005openalex-snapshot

The CXCR4-CXCL12 axis promotes T cell reconstitution via efficient hematopoietic immigration

inferred← citeshttps://doi.org/10.1016/j.jtcvs.2017.08.127openalex-snapshot

Angiogenesis precedes cardiomyocyte migration in regenerating mammalian hearts

inferred← citeshttps://doi.org/10.1016/j.jtcvs.2017.08.150openalex-snapshot

Discussion

inferred← citeshttps://doi.org/10.1016/j.omtm.2020.04.011openalex-snapshot

Delta-1 Functionalized Hydrogel Promotes hESC-Cardiomyocyte Graft Proliferation and Maintains Heart Function Post-Injury

inferred← citeshttps://doi.org/10.1016/j.scr.2014.06.003openalex-snapshot

A neonatal blueprint for cardiac regeneration

inferred← citeshttps://doi.org/10.1016/j.scr.2014.07.003openalex-snapshot

Advances in understanding the mechanism of zebrafish heart regeneration

inferred← citeshttps://doi.org/10.1016/j.semcdb.2019.09.005openalex-snapshot

Zebrafish heart regeneration: Factors that stimulate cardiomyocyte proliferation

inferred← citeshttps://doi.org/10.1016/j.semcdb.2025.103623openalex-snapshot

Force of change: How biomechanical cues drive endothelial plasticity and morphogenesis

inferred← citeshttps://doi.org/10.1016/j.stemcr.2021.05.014openalex-snapshot

Sequential regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium by Ezh1/2

inferred← citeshttps://doi.org/10.1016/j.stemcr.2025.102575openalex-snapshot

Progenitor neighborhoods function as transient niches to sustain olfactory neurogenesis

inferred← citeshttps://doi.org/10.1016/j.ydbio.2015.05.011openalex-snapshot

Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development

inferred← citeshttps://doi.org/10.1016/j.ydbio.2015.07.017openalex-snapshot

Evolution of the chordate regeneration blastema: Differential gene expression and conserved role of notch signaling during siphon regeneration in the ascidian Ciona

inferred← citeshttps://doi.org/10.1016/j.ydbio.2022.04.008openalex-snapshot

Zebrafish heart regeneration after coronary dysfunction-induced cardiac damage

inferred← citeshttps://doi.org/10.1016/j.ydbio.2022.05.010openalex-snapshot

Temporal cell fate determination in the spinal cord is mediated by the duration of Notch signalling

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2022.03.009openalex-snapshot

Coronary vessel formation in development and regeneration: origins and mechanisms

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2023.04.001openalex-snapshot

Regulation of endogenous cardiomyocyte proliferation: The known unknowns

inferred← citeshttps://doi.org/10.1016/j.ymthe.2018.10.021openalex-snapshot

Long Non-coding RNA ECRAR Triggers Post-natal Myocardial Regeneration by Activating ERK1/2 Signaling

inferred← citeshttps://doi.org/10.1038/cr.2015.109openalex-snapshot

G protein-coupled receptor 183 facilitates endothelial-to-hematopoietic transition via Notch1 inhibition

inferred← citeshttps://doi.org/10.1038/nature18310openalex-snapshot

Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesis

inferred← citeshttps://doi.org/10.1038/ncomms13991openalex-snapshot

Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization

inferred← citeshttps://doi.org/10.1038/nrd.2017.106openalex-snapshot

Heart regeneration and repair after myocardial infarction: translational opportunities for novel therapeutics

inferred← citeshttps://doi.org/10.1038/s41392-020-00413-2openalex-snapshot

Regulation of cardiomyocyte fate plasticity: a key strategy for cardiac regeneration

inferred← citeshttps://doi.org/10.1038/s41392-022-00925-zopenalex-snapshot

Signaling pathways and targeted therapy for myocardial infarction

inferred← citeshttps://doi.org/10.1038/s41392-023-01688-xopenalex-snapshot

Ischemia-reperfusion injury: molecular mechanisms and therapeutic targets

inferred← citeshttps://doi.org/10.1038/s41392-026-02673-wopenalex-snapshot

Biologics for cardiovascular diseases: from bench to bedside

inferred← citeshttps://doi.org/10.1038/s41419-020-02781-7openalex-snapshot

p53 isoform Δ113p53 promotes zebrafish heart regeneration by maintaining redox homeostasis

inferred← citeshttps://doi.org/10.1038/s41419-021-04160-2openalex-snapshot

Inhibition of Notch activity promotes pancreatic cytokeratin 5-positive cell differentiation to beta cells and improves glucose homeostasis following acute pancreatitis

inferred← citeshttps://doi.org/10.1038/s41420-023-01457-3openalex-snapshot

IGF2BP3 promotes adult myocardial regeneration by stabilizing MMP3 mRNA through interaction with m6A modification

inferred← citeshttps://doi.org/10.1038/s41467-022-30468-4openalex-snapshot

Activation of Nkx2.5 transcriptional program is required for adult myocardial repair

inferred← citeshttps://doi.org/10.1038/s41467-022-33836-2openalex-snapshot

Brain milieu induces early microglial maturation through the BAX-Notch axis

inferred← citeshttps://doi.org/10.1038/s41467-024-52365-8openalex-snapshot

Endolysosomal dysfunction in radial glia progenitor cells leads to defective cerebral angiogenesis and compromised blood-brain barrier integrity

inferred← citeshttps://doi.org/10.1038/s41467-024-54060-0openalex-snapshot

Harnessing the regenerative potential of interleukin11 to enhance heart repair

inferred← citeshttps://doi.org/10.1038/s41467-025-59070-0openalex-snapshot

An organ-wide spatiotemporal transcriptomic and cellular atlas of the regenerating zebrafish heart

inferred← citeshttps://doi.org/10.1038/s41536-018-0059-yopenalex-snapshot

Parallels between vertebrate cardiac and cutaneous wound healing and regeneration

inferred← citeshttps://doi.org/10.1038/s41536-021-00139-xopenalex-snapshot

Notch-Wnt signal crosstalk regulates proliferation and differentiation of osteoprogenitor cells during intramembranous bone healing

inferred← citeshttps://doi.org/10.1038/s41536-022-00209-8openalex-snapshot

Hippo-Yap/Taz signalling in zebrafish regeneration

inferred← citeshttps://doi.org/10.1038/s41536-023-00293-4openalex-snapshot

Endothelial Brg1 fine-tunes Notch signaling during zebrafish heart regeneration

inferred← citeshttps://doi.org/10.1038/s41536-025-00394-2openalex-snapshot

Revitalizing the heart: strategies and tools for cardiomyocyte regeneration post-myocardial infarction

inferred← citeshttps://doi.org/10.1038/s41569-018-0046-4openalex-snapshot

The epicardium as a hub for heart regeneration

inferred← citeshttps://doi.org/10.1038/s41569-018-0100-2openalex-snapshot

Notch and interacting signalling pathways in cardiac development, disease, and regeneration

inferred← citeshttps://doi.org/10.1038/s41569-020-0400-1openalex-snapshot

Coronary vessel formation in development and disease: mechanisms and insights for therapy

inferred← citeshttps://doi.org/10.1038/s41569-021-00635-zopenalex-snapshot

A change of heart: new roles for cilia in cardiac development and disease

inferred← citeshttps://doi.org/10.1038/s41569-023-00914-xopenalex-snapshot

Animal models to study cardiac regeneration

inferred← citeshttps://doi.org/10.1038/s41586-022-04766-2openalex-snapshot

Generation of specialized blood vessels via lymphatic transdifferentiation

inferred← citeshttps://doi.org/10.1038/s41598-017-02461-1openalex-snapshot

The zebrafish ventricle: A hub of cardiac endothelial cells for in vitro cell behavior studies

inferred← citeshttps://doi.org/10.1038/s41598-018-25490-wopenalex-snapshot

Matrix metalloproteinases (MMPs) mediate leukocyte recruitment during the inflammatory phase of zebrafish heart regeneration

inferred← citeshttps://doi.org/10.1038/s41598-019-45841-5openalex-snapshot

Etv2 transcriptionally regulates Yes1 and promotes cell proliferation during embryogenesis

inferred← citeshttps://doi.org/10.1038/s44161-024-00530-zopenalex-snapshot

Participation of ventricular trabeculae in neonatal cardiac regeneration leads to ectopic recruitment of Purkinje-like cells

inferred← citeshttps://doi.org/10.1038/srep23188openalex-snapshot

Cardiomyocytes in Young Infants With Congenital Heart Disease: a Three-Month Window of Proliferation

inferred← citeshttps://doi.org/10.1039/c9lc01044kopenalex-snapshot

Extended culture and imaging of normal and regenerating adult zebrafish hearts in a fluidic device

inferred← citeshttps://doi.org/10.1073/pnas.1511209112openalex-snapshot

Myocardial NF-κB activation is essential for zebrafish heart regeneration

inferred← citeshttps://doi.org/10.1073/pnas.1605431113openalex-snapshot

Fast revascularization of the injured area is essential to support zebrafish heart regeneration

inferred← citeshttps://doi.org/10.1073/pnas.1722594115openalex-snapshot

Vegfaa instructs cardiac muscle hyperplasia in adult zebrafish

inferred← citeshttps://doi.org/10.1080/26895293.2024.2308904openalex-snapshot

Cardiac regeneration: 20 years of development and update in zebrafish and mouse

inferred← citeshttps://doi.org/10.1083/jcb.201802113openalex-snapshot

Dual regulation of lin28a by Myc is necessary during zebrafish retina regeneration

inferred← citeshttps://doi.org/10.1089/scd.2018.0049openalex-snapshot

Hedgehog and Wnt Signaling Pathways Regulate Tail Regeneration

inferred← citeshttps://doi.org/10.1093/cvr/cvab214openalex-snapshot

Hooked on heart regeneration: the zebrafish guide to recovery

inferred← citeshttps://doi.org/10.1093/cvr/cvv190openalex-snapshot

Extracellular component hyaluronic acid and its receptor Hmmr are required for epicardial EMT during heart regeneration

inferred← citeshttps://doi.org/10.1093/cvr/cvx228openalex-snapshot

Reversible Notch1 acetylation tunes proliferative signalling in cardiomyocytes

inferred← citeshttps://doi.org/10.1093/eurheartj/ehw113openalex-snapshot

Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure

inferred← citeshttps://doi.org/10.1093/jmcb/mjaa046openalex-snapshot

Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation during zebrafish heart regeneration

inferred← citeshttps://doi.org/10.1093/med/9780198757269.003.0005openalex-snapshot

Origin and diversity of embryonic endothelium/endocardium

inferred← citeshttps://doi.org/10.1093/procel/pwac010openalex-snapshot

Single-cell analysis reveals an Angpt4-initiated EPDC-EC-CM cellular coordination cascade during heart regeneration

inferred← citeshttps://doi.org/10.1097/crd.0000000000000806openalex-snapshot

Research Progress on Epicardial Repair After Myocardial Injury

inferred← citeshttps://doi.org/10.1098/rsob.160102openalex-snapshot

Distinct effects of inflammation on preconditioning and regeneration of the adult zebrafish heart

inferred← citeshttps://doi.org/10.1101/2021.06.15.448575openalex-snapshot

Macrophages stimulate epicardial VEGFaa expression to trigger cardiomyocyte proliferation in larval zebrafish heart regeneration

inferred← citeshttps://doi.org/10.1101/2022.09.05.506659openalex-snapshot

Self-assembly of cellular neighborhoods converts stochastic signaling into sustained olfactory neurogenesis

inferred← citeshttps://doi.org/10.1101/2025.04.28.650985openalex-snapshot

A Conserved Venous Remodeling Program Governs Inferior Vena Cava Formation in Zebrafish

inferred← citeshttps://doi.org/10.1101/2025.05.20.655066openalex-snapshot

Bona fide hematopoietic stem cells in zebrafish originate from the supra-intestinal artery

inferred← citeshttps://doi.org/10.1101/490706openalex-snapshot

Retinoid X receptor alpha is a spatiotemporally-specific therapeutic target for doxorubicin-induced cardiomyopathy in adult zebrafish

inferred← citeshttps://doi.org/10.1101/cshperspect.a040766openalex-snapshot

Innate Mechanisms of Heart Regeneration

inferred← citeshttps://doi.org/10.1111/dgd.12602openalex-snapshot

Recovery of the Xenopus laevis heart from ROS‐induced stress utilizes conserved pathways of cardiac regeneration

inferred← citeshttps://doi.org/10.1111/jgh.14110openalex-snapshot

Notch signaling pathway regulates cell cycle in proliferating hepatocytes involved in liver regeneration

inferred← citeshttps://doi.org/10.1111/wrr.12892openalex-snapshot

Reactive oxygen species during heart regeneration in zebrafish: Lessons for future clinical therapies

inferred← citeshttps://doi.org/10.1124/mol.119.118018openalex-snapshot

Interventions in WNT Signaling to Induce Cardiomyocyte Proliferation: Crosstalk with Other Pathways

inferred← citeshttps://doi.org/10.1126/sciadv.adk4694openalex-snapshot

Single-cell chromatin profiling reveals genetic programs activating proregenerative states in nonmyocyte cells

inferred← citeshttps://doi.org/10.1126/sciadv.ady3541openalex-snapshot

A conserved biphasic venous remodeling program governs inferior vena cava formation in zebrafish

inferred← citeshttps://doi.org/10.1126/science.adw0855openalex-snapshot

Spatially resolved single-cell atlas reveals the macroevolutionary trajectory of animal hearts

inferred← citeshttps://doi.org/10.1152/ajpheart.00559.2015openalex-snapshot

Cardiomyocyte proliferation in cardiac development and regeneration: a guide to methodologies and interpretations

inferred← citeshttps://doi.org/10.1159/000490012openalex-snapshot

Gremlin2 Regulates the Differentiation and Function of Cardiac Progenitor Cells via the Notch Signaling Pathway

inferred← citeshttps://doi.org/10.1160/th14-05-0480openalex-snapshot

Vascularisation for cardiac tissue engineering: the extracellular matrix

inferred← citeshttps://doi.org/10.1161/atvbaha.120.314488openalex-snapshot

ETV2 (Ets Variant Transcription Factor 2)- Rhoj Cascade Regulates Endothelial Progenitor Cell Migration During Embryogenesis

inferred← citeshttps://doi.org/10.1161/atvbaha.126.325061openalex-snapshot

Targeting Thrombopoietin/MPL Signaling to Mitigate JAK2V617F-Driven Cardiac Microvascular Disease

inferred← citeshttps://doi.org/10.1161/circresaha.115.305350openalex-snapshot

Endocardial Notch Signaling in Cardiac Development and Disease

inferred← citeshttps://doi.org/10.1161/circresaha.116.309877openalex-snapshot

Notch-Mediated Epigenetic Regulation of Voltage-Gated Potassium Currents

inferred← citeshttps://doi.org/10.1161/circresaha.116.310156openalex-snapshot

Reprogramming of Cardiac Repolarization

inferred← citeshttps://doi.org/10.1161/circresaha.119.315857openalex-snapshot

The Role of the Epicardium During Heart Development and Repair

inferred← citeshttps://doi.org/10.1161/circresaha.119.316500openalex-snapshot

Somatic Gain of KRAS Function in the Endothelium Is Sufficient to Cause Vascular Malformations That Require MEK but Not PI3K Signaling

inferred← citeshttps://doi.org/10.1161/circresaha.124.321567openalex-snapshot

Exploring the Function of Epicardial Cells Beyond the Surface

inferred← citeshttps://doi.org/10.1172/jci.insight.125362openalex-snapshot

Displacement analysis of myocardial mechanical deformation (DIAMOND) reveals segmental susceptibility to doxorubicin-induced injury and regeneration

inferred← citeshttps://doi.org/10.1172/jci83496openalex-snapshot

4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation

inferred← citeshttps://doi.org/10.1172/jci89786openalex-snapshot

Redirecting cardiac growth mechanisms for therapeutic regeneration

inferred← citeshttps://doi.org/10.1172/jci95492openalex-snapshot

The relationship between cardiac endothelium and fibroblasts: it’s complicated

inferred← citeshttps://doi.org/10.1186/1471-2164-15-852openalex-snapshot

Transcriptional response to cardiac injury in the zebrafish: systematic identification of genes with highly concordant activity across in vivo models

inferred← citeshttps://doi.org/10.1186/s12931-025-03393-5openalex-snapshot

Integrative single-cell RNA and ATAC sequencing reveals the impact of chronic cigarette smoking on lung epithelial responses to influenza and hyperoxia

inferred← citeshttps://doi.org/10.1186/s13619-020-00060-6openalex-snapshot

The roles and activation of endocardial Notch signaling in heart regeneration

inferred← citeshttps://doi.org/10.1186/s13619-020-00065-1openalex-snapshot

Cardiac cell type-specific responses to injury and contributions to heart regeneration

inferred← citeshttps://doi.org/10.1186/s13619-020-00072-2openalex-snapshot

The interaction of Notch and Wnt signaling pathways in vertebrate regeneration

inferred← citeshttps://doi.org/10.1186/s13619-021-00075-7openalex-snapshot

Molecular regulation of myocardial proliferation and regeneration

inferred← citeshttps://doi.org/10.1186/s13619-026-00297-7openalex-snapshot

Signaling pathways regulating cardiac regeneration

inferred← citeshttps://doi.org/10.1186/s40779-023-00452-0openalex-snapshot

Regeneration of the heart: from molecular mechanisms to clinical therapeutics

inferred← citeshttps://doi.org/10.1186/s43556-021-00047-yopenalex-snapshot

Targeting cardiomyocyte proliferation as a key approach of promoting heart repair after injury

inferred← citeshttps://doi.org/10.1186/s43556-026-00504-6openalex-snapshot

Cardiac regeneration and repair: the emerging mechanisms and therapeutic approaches

inferred← citeshttps://doi.org/10.1242/bio.062374openalex-snapshot

Interferon signaling is required for early neutrophil recruitment after zebrafish heart injury

inferred← citeshttps://doi.org/10.1242/dev.118687openalex-snapshot

Myocardium and BMP signaling are required for endocardial differentiation

inferred← citeshttps://doi.org/10.1242/dev.126136openalex-snapshot

The AP-1 transcription factor component Fosl2 potentiates the rate of myocardial differentiation from the zebrafish second heart field

inferred← citeshttps://doi.org/10.1242/dev.126649openalex-snapshot

Dynamic microRNA-101a and Fosab expression controls zebrafish heart regeneration

inferred← citeshttps://doi.org/10.1242/dev.131425openalex-snapshot

The force within: endocardial development, mechanotransduction and signalling during cardiac morphogenesis

inferred← citeshttps://doi.org/10.1242/dev.143362openalex-snapshot

Notch signalling restricts inflammation and serpine1 expression in the dynamic endocardium of the regenerating zebrafish heart

inferred← citeshttps://doi.org/10.1242/dev.167692openalex-snapshot

Model systems for regeneration: zebrafish

inferred← citeshttps://doi.org/10.1242/dev.178632openalex-snapshot

H3K27me3-mediated silencing of structural genes is required for zebrafish heart regeneration

inferred← citeshttps://doi.org/10.1242/dev.200654openalex-snapshot

Coupled myovascular expansion directs cardiac growth and regeneration

inferred← citeshttps://doi.org/10.1242/dmm.016170openalex-snapshot

The zebrafish as a tool to identify novel therapies for human cardiovascular disease

inferred← citeshttps://doi.org/10.1242/jeb.205567openalex-snapshot

Cardiac remodeling in response to embryonic crude oil exposure involves unconventional NKX family members and innate immunity genes

inferred← citeshttps://doi.org/10.1371/journal.pone.0139712openalex-snapshot

Decreased Yes-Associated Protein-1 (YAP1) Expression in Pediatric Hearts with Ventricular Septal Defects

inferred← citeshttps://doi.org/10.1371/journal.pone.0232981openalex-snapshot

Active Notch signaling is required for arm regeneration in a brittle star

inferred← citeshttps://doi.org/10.1387/ijdb.200227dqopenalex-snapshot

A roadmap for intestinal regeneration

inferred← citeshttps://doi.org/10.15252/embr.202255764openalex-snapshot

The mitochondrial ribosomal protein mRpL4 regulates Notch signaling

inferred← citeshttps://doi.org/10.17615/2f5d-th16openalex-snapshot

Effect of adrenomedullin over-expression in the cardiovascular system during development and disease

inferred← citeshttps://doi.org/10.17760/d20248779openalex-snapshot

Role of proto-oncogenes, Pi3K, Her2, Braf and Yap1 and adult stem cells in regeneration

inferred← citeshttps://doi.org/10.2174/0929867328666210914115411openalex-snapshot

The Roles of Signaling Pathways in Cardiac Regeneration

inferred← citeshttps://doi.org/10.2174/1389450116666141205153258openalex-snapshot

Stem Cell Aging and Age-Related Cardiovascular Disease: Perspectives of Treatment by Ex-vivo Stem Cell Rejuvenation

inferred← citeshttps://doi.org/10.2174/1389450116666150630110821openalex-snapshot

Epigenetic Regulation of Myocardial Homeostasis, Self-Regeneration and Senescence

inferred← citeshttps://doi.org/10.2174/1574888x10666150113111320openalex-snapshot

Unconventional Players on the Striated Muscle Field: microRNAs, Signaling Pathways and Epigenetic Regulators

inferred← citeshttps://doi.org/10.2217/rme-2022-0161openalex-snapshot

How can the Adult Zebrafish and Neonatal Mice Teach us About Stimulating Cardiac Regeneration in the Human Heart?

inferred← citeshttps://doi.org/10.24310/enbio.v14i177.16701openalex-snapshot

Terapias celulares experimentales para el tratamiento del infarto de miocardio: lecciones de la regeneración y reparación cardíaca en vertebrados no humanos

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