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Prefrontal neurons encode context-based response execution and inhibition in reward seeking and extinction

https://doi.org/10.1073/pnas.1507611112
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/syn.10279openalex-snapshot
Differential projections of the infralimbic and prelimbic cortex in the rat
inferredcites →https://doi.org/10.1002/syn.20129openalex-snapshot
Prefrontal cortical cell firing during maintenance, extinction, and reinstatement of goal‐directed behavior for natural reward
inferredcites →https://doi.org/10.1007/s00213-004-2068-3openalex-snapshot
Local glutamate receptor antagonism in the rat prefrontal cortex disrupts response inhibition in a visuospatial attentional task
inferredcites →https://doi.org/10.1016/j.bbr.2003.09.016openalex-snapshot
Learning-related changes in response patterns of prefrontal neurons during instrumental conditioning
inferredcites →https://doi.org/10.1016/j.bbr.2003.09.025openalex-snapshot
Inactivation of the infralimbic prefrontal cortex reinstates goal-directed responding in overtrained rats
inferredcites →https://doi.org/10.1016/j.brainres.2014.12.024openalex-snapshot
Differential roles of medial prefrontal subregions in the regulation of drug seeking
inferredcites →https://doi.org/10.1016/j.neubiorev.2004.09.006openalex-snapshot
Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates
inferredcites →https://doi.org/10.1016/j.neuron.2006.10.021openalex-snapshot
Top-Down Control of Motor Cortex Ensembles by Dorsomedial Prefrontal Cortex
inferredcites →https://doi.org/10.1016/j.neuron.2010.03.029openalex-snapshot
Abrupt Transitions between Prefrontal Neural Ensemble States Accompany Behavioral Transitions during Rule Learning
inferredcites →https://doi.org/10.1016/j.neuron.2010.03.033openalex-snapshot
Distinct Roles of Rodent Orbitofrontal and Medial Prefrontal Cortex in Decision Making
inferredcites →https://doi.org/10.1016/j.neuron.2012.12.002openalex-snapshot
The Role of Medial Prefrontal Cortex in Memory and Decision Making
inferredcites →https://doi.org/10.1016/j.neuron.2013.05.038openalex-snapshot
A Dual Operator View of Habitual Behavior Reflecting Cortical and Striatal Dynamics
inferredcites →https://doi.org/10.1016/j.neuroscience.2008.06.037openalex-snapshot
Contributions of the amygdala and medial prefrontal cortex to incentive cue responding
inferredcites →https://doi.org/10.1037//0735-7044.109.4.681openalex-snapshot
Differential contribution of dorsal and ventral medial prefrontal cortex to the acquisition and extinction of conditioned fear in rats.
inferredcites →https://doi.org/10.1037/0735-7044.109.4.681openalex-snapshot
Differential contribution of dorsal and ventral medial prefrontal cortex to the acquisition and extinction of conditioned fear in rats.
inferredcites →https://doi.org/10.1037/a0016330openalex-snapshot
The rat prelimbic cortex mediates inhibitory response control but not the consolidation of instrumental learning.
inferredcites →https://doi.org/10.1038/nn2066openalex-snapshot
Choice, uncertainty and value in prefrontal and cingulate cortex
inferredcites →https://doi.org/10.1038/npp.2009.131openalex-snapshot
Human and Rodent Homologies in Action Control: Corticostriatal Determinants of Goal-Directed and Habitual Action
inferredcites →https://doi.org/10.1038/nrn1535openalex-snapshot
Neuronal signalling of fear memory
inferredcites →https://doi.org/10.1073/pnas.0407332102openalex-snapshot
Coding for spatial goals in the prelimbic/infralimbic area of the rat frontal cortex
inferredcites →https://doi.org/10.1073/pnas.1114415109openalex-snapshot
Contextual encoding by ensembles of medial prefrontal cortex neurons
inferredcites →https://doi.org/10.1093/cercor/13.4.400openalex-snapshot
Coordination of Actions and Habits in the Medial Prefrontal Cortex of Rats
inferredcites →https://doi.org/10.1101/lm.1041309openalex-snapshot
Extinction circuits for fear and addiction overlap in prefrontal cortex
inferredcites →https://doi.org/10.1111/j.1460-9568.2004.03526.xopenalex-snapshot
Reward expectation, orientation of attention and locus coeruleus‐medial frontal cortex interplay during learning
inferredcites →https://doi.org/10.1111/j.1460-9568.2007.05486.xopenalex-snapshot
Lesions of rat infralimbic cortex enhance renewal of extinguished appetitive Pavlovian responding
inferredcites →https://doi.org/10.1111/j.1460-9568.2009.06834.xopenalex-snapshot
Transient role of the rat prelimbic cortex in goal‐directed behaviour
inferredcites →https://doi.org/10.1146/annurev.neuro.24.1.167openalex-snapshot
An Integrative Theory of Prefrontal Cortex Function
inferredcites →https://doi.org/10.1186/1756-6606-5-36openalex-snapshot
Modulation of medial prefrontal cortical activity using in vivo recordings and optogenetics
inferredcites →https://doi.org/10.1371/journal.pone.0057575openalex-snapshot
Prelimbic and Infralimbic Neurons Signal Distinct Aspects of Appetitive Instrumental Behavior
inferredcites →https://doi.org/10.1523/jneurosci.1142-09.2009openalex-snapshot
Anterior Cingulate Neurons Represent Errors and Preparatory Attention within the Same Behavioral Sequence
inferredcites →https://doi.org/10.1523/jneurosci.1543-11.2011openalex-snapshot
Prefrontal and Monoaminergic Contributions to Stop-Signal Task Performance in Rats
inferredcites →https://doi.org/10.1523/jneurosci.3216-13.2014openalex-snapshot
Orbitofrontal Cortical Neurons Encode Expectation-Driven Initiation of Reward-Seeking
inferredcites →https://doi.org/10.1523/jneurosci.3891-11.2012openalex-snapshot
Prefrontal Cortex Mediates Extinction of Responding by Two Distinct Neural Mechanisms in Accumbens Shell
inferredcites →https://doi.org/10.1523/jneurosci.4240-09.2010openalex-snapshot
Amygdala Neural Encoding of the Absence of Reward during Extinction
inferredcites →https://doi.org/10.1523/jneurosci.6068-08.2009openalex-snapshot
Rat Prefrontal Cortical Neurons Selectively Code Strategy Switches

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Basal Forebrain Projections to the Retrosplenial and Cingulate Cortex in Rats
inferred← citeshttps://doi.org/10.1002/jnr.23736openalex-snapshot
Prefrontal infralimbic cortex mediates competition between excitation and inhibition of body movements during pavlovian fear conditioning
inferred← citeshttps://doi.org/10.1002/jnr.25025openalex-snapshot
Comparison of prefrontal cortex sucrose seeking ensembles engaged in multiple seeking sessions: Context is key
inferred← citeshttps://doi.org/10.1002/jnr.70150openalex-snapshot
A Selective Cortico‐Limbic Network Organizes Behavior During Reward Seeking Under Threat
inferred← citeshttps://doi.org/10.1007/s00213-018-5024-3openalex-snapshot
Common neurocircuitry mediating drug and fear relapse in preclinical models
inferred← citeshttps://doi.org/10.1007/s00213-022-06287-2openalex-snapshot
Prelimbic and infralimbic medial prefrontal cortex neuron activity signals cocaine seeking variables across multiple timescales
inferred← citeshttps://doi.org/10.1007/s00213-024-06597-7openalex-snapshot
The secondary visual cortex mediated the enhancement of associative learning on methamphetamine self-administration behaviors
inferred← citeshttps://doi.org/10.1007/s00213-024-06633-6openalex-snapshot
Effects of chronic naltrexone treatment on relapse-related behavior and neural responses to fentanyl in awake nonhuman primates
inferred← citeshttps://doi.org/10.1007/s00429-025-03055-8openalex-snapshot
Medial prefrontal cortex circuit dynamics involved in stage-specific addiction
inferred← citeshttps://doi.org/10.1007/s00429-026-03071-2openalex-snapshot
VTA-forebrain connectivity moderates adaptive behavior
inferred← citeshttps://doi.org/10.1007/s11726-017-0980-4openalex-snapshot
Effect of reward alteration following acupuncture for morphine withdrawal rats on neuronal discharges in the ventral medial prefrontal cortex
inferred← citeshttps://doi.org/10.1016/b978-0-12-823453-2.00001-1openalex-snapshot
Prefrontal Cortical (PFC) circuits
inferred← citeshttps://doi.org/10.1016/b978-0-443-29867-7.00037-2openalex-snapshot
Dopamine modulation of synaptic transmission in drug addiction
inferred← citeshttps://doi.org/10.1016/bs.irn.2020.11.007openalex-snapshot
Integration of value and action in medial prefrontal neural systems
inferred← citeshttps://doi.org/10.1016/bs.irn.2020.11.010openalex-snapshot
Prefrontal contributions to action control in rodents
inferred← citeshttps://doi.org/10.1016/j.alcohol.2021.08.006openalex-snapshot
Replicability in measures of attentional set-shifting task performance predicting chronic heavy drinking in rhesus monkeys
inferred← citeshttps://doi.org/10.1016/j.arcmed.2019.09.003openalex-snapshot
Drug-related Virtual Reality Cue Reactivity is Associated with Gamma Activity in Reward and Executive Control Circuit in Methamphetamine Use Disorders
inferred← citeshttps://doi.org/10.1016/j.bbi.2021.08.216openalex-snapshot
Acute neuroinflammation increases excitability of prefrontal parvalbumin interneurons and their functional recruitment during novel object recognition
inferred← citeshttps://doi.org/10.1016/j.bbr.2022.114248openalex-snapshot
Neural correlates of recall and extinction in a rat model of appetitive Pavlovian conditioning
inferred← citeshttps://doi.org/10.1016/j.biopha.2026.119801openalex-snapshot
Individual differences in brain cocaine pharmacokinetics predict cocaine intake patterns in rats
inferred← citeshttps://doi.org/10.1016/j.biopsych.2020.04.005openalex-snapshot
Cortical Regulation of the Ability to Resist Temptation for Punishment-Paired Alcohol
inferred← citeshttps://doi.org/10.1016/j.biopsych.2021.08.008openalex-snapshot
Extinction of Cocaine Memory Depends on a Feed-Forward Inhibition Circuit Within the Medial Prefrontal Cortex
inferred← citeshttps://doi.org/10.1016/j.brainres.2014.12.024openalex-snapshot
Differential roles of medial prefrontal subregions in the regulation of drug seeking
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.01.023openalex-snapshot
Opposing Regulation of Cocaine Seeking by Glutamate and GABA Neurons in the Ventral Pallidum
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111487openalex-snapshot
Visuomotor learning promotes visually evoked activity in the medial prefrontal cortex
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.113618openalex-snapshot
Distributed and specific encoding of sensory, motor, and decision information in the mouse neocortex during goal-directed behavior
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.115022openalex-snapshot
Individual differences in prelimbic neural representation of food and cocaine seeking
inferred← citeshttps://doi.org/10.1016/j.cortex.2016.01.005openalex-snapshot
Human ventromedial prefrontal lesions alter incentivisation by reward
inferred← citeshttps://doi.org/10.1016/j.cub.2016.08.034openalex-snapshot
Imbalanced Activity in the Orbitofrontal Cortex and Nucleus Accumbens Impairs Behavioral Inhibition
inferred← citeshttps://doi.org/10.1016/j.cub.2021.11.004openalex-snapshot
Neural reinstatement reveals divided organization of fear and extinction memories in the human brain
inferred← citeshttps://doi.org/10.1016/j.cub.2025.07.035openalex-snapshot
Dopaminergic projections to the prefrontal cortex are critical for rapid threat avoidance learning
inferred← citeshttps://doi.org/10.1016/j.drugalcdep.2024.112475openalex-snapshot
Distinct populations suppress or escalate intake of cocaine paired with aversive quinine
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2019.11.007openalex-snapshot
Neural circuits linking sleep and addiction: Animal models to understand why select individuals are more vulnerable to substance use disorders after sleep deprivation
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2021.02.021openalex-snapshot
Motivational competition and the paraventricular thalamus
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2021.10.002openalex-snapshot
Infralimbic cortex functioning across motivated behaviors: Can the differences be reconciled?
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2022.104569openalex-snapshot
The rodent medial prefrontal cortex and associated circuits in orchestrating adaptive behavior under variable demands
inferred← citeshttps://doi.org/10.1016/j.neulet.2017.09.015openalex-snapshot
Nitric oxide in the medial prefrontal cortex contributes to the acquisition of cocaine place preference and synaptic plasticity in the laterodorsal tegmental nucleus
inferred← citeshttps://doi.org/10.1016/j.neulet.2022.136710openalex-snapshot
Prelimbic medial prefrontal cortex has bidirectional control over the expression of behavioral sensitization to 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) depending on the context of drug administration
inferred← citeshttps://doi.org/10.1016/j.neulet.2026.138506openalex-snapshot
Medial prefrontal Cortex, dopamine and glutamate modulation in regulating Reward-Seeking and frustration responses
inferred← citeshttps://doi.org/10.1016/j.neures.2018.08.017openalex-snapshot
Prefrontal circuit organization for executive control
inferred← citeshttps://doi.org/10.1016/j.neuron.2019.04.015openalex-snapshot
Increased Cocaine Motivation Is Associated with Degraded Spatial and Temporal Representations in IL-NAc Neurons
inferred← citeshttps://doi.org/10.1016/j.neuron.2019.05.024openalex-snapshot
Embracing Complexity in Defensive Networks
inferred← citeshttps://doi.org/10.1016/j.neuron.2019.11.018openalex-snapshot
Dopaminergic and Prefrontal Basis of Learning from Sensory Confidence and Reward Value
inferred← citeshttps://doi.org/10.1016/j.neuron.2020.05.039openalex-snapshot
Different Multidimensional Representations across the Amygdalo-Prefrontal Network during an Approach-Avoidance Task
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2017.10.024openalex-snapshot
Endogenous glutamate within the prelimbic and infralimbic cortices regulates the incubation of cocaine-seeking in rats
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2018.10.027openalex-snapshot
Muscarinic receptors regulate auditory and prefrontal cortical communication during auditory processing
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2019.107672openalex-snapshot
Glutamate receptor interacting protein acts within the prefrontal cortex to blunt cocaine seeking
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2021.108496openalex-snapshot
Alcohol and sweet reward are encoded by distinct meta-ensembles
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2021.108501openalex-snapshot
Alcohol reduces the activity of somatostatin interneurons in the mouse prefrontal cortex: A neural basis for its disinhibitory effect?
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2022.109046openalex-snapshot
Blockade of corticotropin-releasing factor-1 receptors in the infralimbic cortex prevents stress-induced reinstatement of alcohol seeking in male Wistar rats: Evidence of interaction between CRF1 and orexin receptor signaling
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2023.109762openalex-snapshot
Non-Consummatory Behavior Signals Predict Aversion-Resistant Alcohol Drinking in Head-Fixed Mice
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2024.110114openalex-snapshot
Alcohol, flexible behavior, and the prefrontal cortex: Functional changes underlying impaired cognitive flexibility
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2026.110895openalex-snapshot
Functional interaction between orexin/CRF and orexin/dynorphin transmission in the infralimbic cortex modulates the stress-induced reinstatement of alcohol-seeking behavior in male and female Wistar rats
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2016.08.022openalex-snapshot
Ifenprodil attenuates the acquisition and expression of methamphetamine-induced behavioral sensitization and activation of Ras-ERK1/2 cascade in the caudate putamen
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2016.10.043openalex-snapshot
A food-predictive cue attributed with incentive salience engages subcortical afferents and efferents of the paraventricular nucleus of the thalamus
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2024.03.012openalex-snapshot
VTA Excitatory Neurons Control Reward-driven Behavior by Modulating Infralimbic Cortical Firing
inferred← citeshttps://doi.org/10.1016/j.nlm.2025.108038openalex-snapshot
The Infralimbic, but not the Prelimbic Cortex is needed for a Complex Olfactory Memory Task
inferred← citeshttps://doi.org/10.1016/j.pbb.2017.07.006openalex-snapshot
Neural systems mediating the inhibition of cocaine-seeking behaviors
inferred← citeshttps://doi.org/10.1016/j.pbb.2025.173958openalex-snapshot
Differential reductions in alcohol consumption and cue-induced alcohol-seeking behavior following mGlu5 receptor inhibition in the prelimbic vs. infralimbic subregions of the rat prefrontal cortex
inferred← citeshttps://doi.org/10.1016/j.pbb.2025.174088openalex-snapshot
Biomolecular correlates of incubated sucrose-seeking within ventromedial prefrontal cortex are sex- and subregion-selective
inferred← citeshttps://doi.org/10.1016/j.physbeh.2022.113938openalex-snapshot
Prelimbic cortex neural encoding dynamically tracks expected outcome value
inferred← citeshttps://doi.org/10.1016/j.pnpbp.2022.110523openalex-snapshot
Corticotropin-releasing factor receptor 1 in infralimbic cortex modulates social stress-altered decision-making
inferred← citeshttps://doi.org/10.1016/j.tins.2018.08.011openalex-snapshot
Neural Circuits for Goal-Directed Sensorimotor Transformations
inferred← citeshttps://doi.org/10.1016/j.ynstr.2024.100695openalex-snapshot
Interaction between corticotropin-releasing factor, orexin, and dynorphin in the infralimbic cortex may mediate exacerbated alcohol-seeking behavior
inferred← citeshttps://doi.org/10.1037/bne0000349openalex-snapshot
The basolateral amygdala-medial prefrontal cortex circuitry regulates behavioral flexibility during appetitive reversal learning.
inferred← citeshttps://doi.org/10.1037/bne0000426openalex-snapshot
Dopamine and noradrenaline modulation of goal-directed behavior in orbital and medial prefrontal cortex: Toward a division of labor?
inferred← citeshttps://doi.org/10.1037/bne0000570openalex-snapshot
Prelimbic cortex inactivation prevents ABA renewal based on stress state.
inferred← citeshttps://doi.org/10.1037/pne0000207openalex-snapshot
The role of the ventromedial prefrontal cortex and context in regulating fear learning and extinction.
inferred← citeshttps://doi.org/10.1038/nature21376openalex-snapshot
Prefrontal cortex output circuits guide reward seeking through divergent cue encoding
inferred← citeshttps://doi.org/10.1038/nn.4553openalex-snapshot
Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment
inferred← citeshttps://doi.org/10.1038/s41386-018-0235-1openalex-snapshot
Drug-taking in a socio-sexual context enhances vulnerability for addiction in male rats
inferred← citeshttps://doi.org/10.1038/s41386-019-0469-6openalex-snapshot
Response-contingent optogenetics to discover the mechanisms of nicotine-cue associations
inferred← citeshttps://doi.org/10.1038/s41386-019-0557-7openalex-snapshot
Dissociable roles for the ventral and dorsal medial prefrontal cortex in cue-guided risk/reward decision making
inferred← citeshttps://doi.org/10.1038/s41386-021-01067-6openalex-snapshot
Inactivation of the infralimbic cortex decreases discriminative stimulus-controlled relapse to cocaine seeking in rats
inferred← citeshttps://doi.org/10.1038/s41386-021-01131-1openalex-snapshot
Prefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stopping model
inferred← citeshttps://doi.org/10.1038/s41386-022-01428-9openalex-snapshot
Altered neuronal activity in the ventromedial prefrontal cortex drives nicotine intake escalation
inferred← citeshttps://doi.org/10.1038/s41386-026-02452-9openalex-snapshot
Top-down control of sustained attention by medial prefrontal cortex—locus coeruleus (mPFC-LC) projection neurons during the rodent continuous performance test (rCPT)
inferred← citeshttps://doi.org/10.1038/s41401-026-01909-3openalex-snapshot
A prelimbic cortex-lateral hypothalamus circuit regulates acquisition of alprazolam-induced conditioned place preference in male mice
inferred← citeshttps://doi.org/10.1038/s41467-019-11799-1openalex-snapshot
Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues
inferred← citeshttps://doi.org/10.1038/s41467-022-31731-4openalex-snapshot
Compulsive alcohol drinking in rodents is associated with altered representations of behavioral control and seeking in dorsal medial prefrontal cortex
inferred← citeshttps://doi.org/10.1038/s41583-020-0276-4openalex-snapshot
The neural and computational systems of social learning
inferred← citeshttps://doi.org/10.1038/s41586-025-09902-2openalex-snapshot
Prefrontal neural geometry of learned cues guides motivated behaviours
inferred← citeshttps://doi.org/10.1038/s41598-019-40532-7openalex-snapshot
Prelimbic and infralimbic cortical inactivations attenuate contextually driven discriminative responding for reward
inferred← citeshttps://doi.org/10.1038/s41598-023-35898-8openalex-snapshot
Circadian desynchronization disrupts physiological rhythms of prefrontal cortex pyramidal neurons in mice
inferred← citeshttps://doi.org/10.1073/pnas.2505378122openalex-snapshot
Distinct prelimbic cortex ensembles encode response execution and inhibition
inferred← citeshttps://doi.org/10.1080/01621459.2015.1116988openalex-snapshot
A Dynamic Bayesian Model for Characterizing Cross-Neuronal Interactions During Decision-Making
inferred← citeshttps://doi.org/10.1093/cercor/bhad211openalex-snapshot
Neuroanatomical signatures associated with dispositional optimism predict COVID-19-related posttraumatic stress symptoms
inferred← citeshttps://doi.org/10.1098/rsob.250177openalex-snapshot
Parental rearing shapes brain functional networks and socio-sexual behaviours in the prairie vole
inferred← citeshttps://doi.org/10.1101/2020.04.06.027888openalex-snapshot
Punishment history biases corticothalamic responses to motivationally-significant stimuli
inferred← citeshttps://doi.org/10.1101/2020.10.30.362962openalex-snapshot
Oscillatory activity in alpha/beta frequencies coordinates auditory and prefrontal cortices during extinction learning
inferred← citeshttps://doi.org/10.1101/2021.03.15.435169openalex-snapshot
Compulsive drinking is associated with neural activity patterns reflecting diminished behavioral control and enhanced seeking representations in dorsal medial prefrontal cortex
inferred← citeshttps://doi.org/10.1101/2022.09.28.509892openalex-snapshot
Neural Correlates of Extinction in a Rat Model of Appetitive Pavlovian Conditioning
inferred← citeshttps://doi.org/10.1101/2023.03.02.530902openalex-snapshot
Glutamatergic neurons in the infralimbic cortex for motivational response of pain relief induced by electroacupuncture
inferred← citeshttps://doi.org/10.1101/2023.11.07.565069openalex-snapshot
Divergent reward cue representations in prefrontal cortex underlie differences in reward motivation between adolescents and adults
inferred← citeshttps://doi.org/10.1101/2024.05.20.595065openalex-snapshot
The Prefrontal Cortex to the Hippocampus Glutamatergic Pathway Regulates Reward Effects of Methamphetamine
inferred← citeshttps://doi.org/10.1101/2024.10.16.618207openalex-snapshot
Prefrontal orchestration: a cortical network for rodent motor inhibition
inferred← citeshttps://doi.org/10.1101/2024.11.08.622733openalex-snapshot
Medial prefrontal cortical neurotransmitters reactive to relapse-promoting and relapse-suppressing cues in rats trained to self-administer cocaine or alcohol
inferred← citeshttps://doi.org/10.1101/2025.10.06.680770openalex-snapshot
Non-overlapping social and food reward representations in the basolateral amygdala
inferred← citeshttps://doi.org/10.1101/2025.11.06.687050openalex-snapshot
Basolateral Amygdala Projections to the Prelimbic Cortex Suppress the Motivational Value of Reward-Associated Cues
inferred← citeshttps://doi.org/10.1101/411413openalex-snapshot
Neural basis of learning guided by sensory confidence and reward value
inferred← citeshttps://doi.org/10.1111/acer.14264openalex-snapshot
Possible Role of CRF‐Hcrt Interaction in the Infralimbic Cortex in the Emergence and Maintenance of Compulsive Alcohol‐Seeking Behavior
inferred← citeshttps://doi.org/10.1111/adb.12434openalex-snapshot
The infralimbic and prelimbic cortices contribute to the inhibitory control of cocaine‐seeking behavior during a discriminative stimulus task in rats
inferred← citeshttps://doi.org/10.1111/bph.16015openalex-snapshot
Blockade of orexin receptors in the infralimbic cortex prevents stress‐induced reinstatement of alcohol‐seeking behaviour in alcohol‐dependent rats
inferred← citeshttps://doi.org/10.1111/ejn.13905openalex-snapshot
Synchronization in the prefrontal–striatal circuit tracks behavioural choice in a go–no‐go task in rats
inferred← citeshttps://doi.org/10.1111/ejn.70574openalex-snapshot
Psilocybin Decreases Preference for Large Rewards Accompanied by Increased Activity of Parvalbumin Neurons With Perineuronal Nets in the Medial Prefrontal Cortex
inferred← citeshttps://doi.org/10.1111/gbb.12344openalex-snapshot
Reprogramming of mPFC transcriptome and function in alcohol dependence
inferred← citeshttps://doi.org/10.1146/annurev-neuro-070815-014106openalex-snapshot
Reward and Aversion
inferred← citeshttps://doi.org/10.1152/physrev.00016.2020openalex-snapshot
Behavioral and neurobiological mechanisms of pavlovian and instrumental extinction learning
inferred← citeshttps://doi.org/10.1155/2022/3759181openalex-snapshot
Multidimensional Pain Modulation by Acupuncture Analgesia: The Reward Effect of Acupuncture on Pain Relief
inferred← citeshttps://doi.org/10.1172/jci.insight.126283openalex-snapshot
VIPergic neurons of the infralimbic and prelimbic cortices control palatable food intake through separate cognitive pathways
inferred← citeshttps://doi.org/10.1177/0269881119844180openalex-snapshot
The medial prefrontal cortex is required for responding to alcohol-predictive cues but only in the absence of alcohol delivery
inferred← citeshttps://doi.org/10.1177/0269881119874414openalex-snapshot
The presence of a social stimulus reduces cocaine-seeking in a place preference conditioning paradigm
inferred← citeshttps://doi.org/10.1177/13872877251376293openalex-snapshot
Amyloid-β alters medial prefrontal cortex encoding of temporal order task
inferred← citeshttps://doi.org/10.1186/s13020-026-01349-5openalex-snapshot
A top–down neural circuit for affective-motivational responses of pain relief induced by electroacupuncture
inferred← citeshttps://doi.org/10.1371/journal.pone.0286209openalex-snapshot
Selective ablation of VIP interneurons in the rodent prefrontal cortex results in increased impulsivity
inferred← citeshttps://doi.org/10.1523/eneuro.0105-16.2016openalex-snapshot
Frontostriatal Circuit Dynamics Correlate with Cocaine Cue-Evoked Behavioral Arousal during Early Abstinence
inferred← citeshttps://doi.org/10.1523/eneuro.0229-25.2025openalex-snapshot
Disrupted Neuronal Dynamics of Reward Encoding in the Medial Prefrontal Cortex and the Ventral Tegmental Area after Episodic Social Stress
inferred← citeshttps://doi.org/10.1523/eneuro.0246-20.2020openalex-snapshot
Pharmacological Inactivation of Medial Prefrontal Cortex Does Not Support Dichotomous “Go/Stop” Roles for Dorsal and Ventral Subdivisions in Natural Reward Seeking in Rats
inferred← citeshttps://doi.org/10.1523/eneuro.0296-19.2019openalex-snapshot
Differential Effects of Dorsal and Ventral Medial Prefrontal Cortex Inactivation during Natural Reward Seeking, Extinction, and Cue-Induced Reinstatement
inferred← citeshttps://doi.org/10.1523/eneuro.0373-20.2021openalex-snapshot
Food-Seeking Behavior Is Mediated by Fos-Expressing Neuronal Ensembles Formed at First Learning in Rats
inferred← citeshttps://doi.org/10.1523/eneuro.0402-19.2020openalex-snapshot
Orbitofrontal Cortex Encodes Preference for Alcohol
inferred← citeshttps://doi.org/10.1523/eneuro.0460-19.2020openalex-snapshot
Infralimbic Cortex Biases Preference Decision Making for Offspring over Competing Cocaine-Associated Stimuli in New Mother Rats
inferred← citeshttps://doi.org/10.1523/jneurosci.0026-18.2018openalex-snapshot
Choice for Drug or Natural Reward Engages Largely Overlapping Neuronal Ensembles in the Infralimbic Prefrontal Cortex
inferred← citeshttps://doi.org/10.1523/jneurosci.0146-26.2026openalex-snapshot
Medial Prefrontal Cortex Innervation of the Basal Forebrain Regulates Behavioral Activation with Prelimbic and Infralimbic Projections Contributing to Distinct Affective Functions in Rats
inferred← citeshttps://doi.org/10.1523/jneurosci.0374-25.2025openalex-snapshot
The Top-Down of Prefrontal Cortex to the Hippocampus Glutamatergic Pathway Regulates Reward Memory of Methamphetamine
inferred← citeshttps://doi.org/10.1523/jneurosci.0414-20.2020openalex-snapshot
Prelimbic and Infralimbic Prefrontal Regulation of Active and Inhibitory Avoidance and Reward-Seeking
inferred← citeshttps://doi.org/10.1523/jneurosci.1291-15.2016openalex-snapshot
Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine-Dependent Manner to Drive Cued Reinstatement of Cocaine Seeking
inferred← citeshttps://doi.org/10.1523/jneurosci.1387-25.2026openalex-snapshot
Aberrant Medial Prefrontal Cortex Activity and Flexible Behavior in the TgF344-AD Rat Model of Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1523/jneurosci.2175-21.2022openalex-snapshot
Cortico-Striatal Control over Adaptive Goal-Directed Responding Elicited by Cues Signaling Sucrose Reward or Punishment
inferred← citeshttps://doi.org/10.1523/jneurosci.2532-18.2019openalex-snapshot
Prelimbic Cortical Neurons Track Preferred Reward Value and Reflect Impulsive Choice during Delay Discounting Behavior
inferred← citeshttps://doi.org/10.1523/jneurosci.2579-17.2018openalex-snapshot
Neural Activity in Ventral Medial Prefrontal Cortex Is Modulated More Before Approach Than Avoidance During Reinforced and Extinction Trial Blocks
inferred← citeshttps://doi.org/10.1523/jneurosci.2588-20.2021openalex-snapshot
Coordinated Prefrontal State Transition Leads Extinction of Reward-Seeking Behaviors
inferred← citeshttps://doi.org/10.1523/jneurosci.2873-16.2017openalex-snapshot
Prefrontal Cortex KCa2 Channels Regulate mGlu5-Dependent Plasticity and Extinction of Alcohol-Seeking Behavior
inferred← citeshttps://doi.org/10.1523/jneurosci.3761-16.2017openalex-snapshot
Bidirectional Modulation of Intrinsic Excitability in Rat Prelimbic Cortex Neuronal Ensembles and Non-Ensembles after Operant Learning
inferred← citeshttps://doi.org/10.1523/jneurosci.3821-16.2017openalex-snapshot
Extinction of Cocaine Seeking Requires a Window of Infralimbic Pyramidal Neuron Activity after Unreinforced Lever Presses
inferred← citeshttps://doi.org/10.22122/ahj.v10i3.613openalex-snapshot
Modulation of Drug Craving in Crystalline-Heroin Users by Transcranial Direct Current Stimulation of Dorsolateral Prefrontal Cortex.
inferred← citeshttps://doi.org/10.25394/pgs.11337296.v1openalex-snapshot
Impact of Acute Ethanol Injections on Medial Prefrontal Cortex Neural Activity
inferred← citeshttps://doi.org/10.31234/osf.io/b7euxopenalex-snapshot
An arbiter model of motivational selection
inferred← citeshttps://doi.org/10.31234/osf.io/gt5fdopenalex-snapshot
Dopamine and noradrenaline modulation of goal-directed behaviour in prefrontal areas: Toward a division of labour?
inferred← citeshttps://doi.org/10.3389/fnbeh.2015.00298openalex-snapshot
The Role of the Medial Prefrontal Cortex in the Conditioning and Extinction of Fear
inferred← citeshttps://doi.org/10.3389/fnbeh.2021.737960openalex-snapshot
Effects of Biological Sex and Stress Exposure on Ventromedial Prefrontal Regulation of Mood-Related Behaviors
inferred← citeshttps://doi.org/10.3389/fnbeh.2022.977474openalex-snapshot
From ensembles to meta-ensembles: Specific reward encoding by correlated network activity
inferred← citeshttps://doi.org/10.3389/fnbeh.2025.1552055openalex-snapshot
Higher levels of D2R and D3R in the frontal–striatal regions are associated with reduced perseverative reward seeking after opioid abstinence
inferred← citeshttps://doi.org/10.3389/fneur.2016.00114openalex-snapshot
Intrusive Thoughts Elicited by Direct Electrical Stimulation during Stereo-Electroencephalography
inferred← citeshttps://doi.org/10.3389/fnins.2023.1201345openalex-snapshot
Maternal neglect alters reward-anticipatory behavior, social status stability, and reward circuit activation in adult male rats
inferred← citeshttps://doi.org/10.3389/fnins.2026.1756644openalex-snapshot
Pairing extinction training with vagus nerve stimulation reduces drug-seeking by altering activity in afferents to the medial prefrontal cortex
inferred← citeshttps://doi.org/10.3389/fnsys.2026.1702298openalex-snapshot
dCA1 cells encode and update contextual place preference
inferred← citeshttps://doi.org/10.3389/fpsyt.2020.00011openalex-snapshot
Transgenic Analyses of Homer2 Function Within Nucleus Accumbens Subregions in the Regulation of Methamphetamine Reward and Reinforcement in Mice
inferred← citeshttps://doi.org/10.3724/sp.j.1041.2023.00556openalex-snapshot
The function of mPFC-NAc circuit in decision impulsivity: A study based on an animal model
inferred← citeshttps://doi.org/10.64898/2025.12.01.691673openalex-snapshot
Top-down control of sustained attention by the medial prefrontal cortex (mPFC) - locus coeruleus (LC) circuit during the rodent continuous performance test (rCPT)
inferred← citeshttps://doi.org/10.64898/2025.12.22.696123openalex-snapshot
Psilocybin decreases reward-seeking behavior accompanied by increased activity of parvalbumin neurons with perineuronal nets in the medial prefrontal cortex
inferred← citeshttps://doi.org/10.7554/elife.21920openalex-snapshot
Distinct memory engrams in the infralimbic cortex of rats control opposing environmental actions on a learned behavior
inferred← citeshttps://doi.org/10.7554/elife.33107openalex-snapshot
Ventral pallidal encoding of reward-seeking behavior depends on the underlying associative structure
inferred← citeshttps://doi.org/10.7554/elife.57634openalex-snapshot
Aversive stimuli bias corticothalamic responses to motivationally significant cues
inferred← citeshttps://doi.org/10.7554/elife.65764openalex-snapshot
Specialized coding patterns among dorsomedial prefrontal neuronal ensembles predict conditioned reward seeking
inferred← citeshttps://doi.org/10.7554/elife.74950openalex-snapshot
Neural correlates and determinants of approach–avoidance conflict in the prelimbic prefrontal cortex
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