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Ionic liquids for oral insulin delivery

https://doi.org/10.1073/pnas.1722338115
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/adhm.201600086openalex-snapshot
Choline and Geranate Deep Eutectic Solvent as a Broad‐Spectrum Antiseptic Agent for Preventive and Therapeutic Applications
inferredcites →https://doi.org/10.1002/adhm.201601411openalex-snapshot
Transdermal Protein Delivery Using Choline and Geranate (CAGE) Deep Eutectic Solvent
inferredcites →https://doi.org/10.1002/biot.201500603openalex-snapshot
Recent advances in exploiting ionic liquids for biomolecules: Solubility, stability and applications
inferredcites →https://doi.org/10.1002/jps.20750openalex-snapshot
Preparation of insulin loaded PLGA-Hp55 nanoparticles for oral delivery
inferredcites →https://doi.org/10.1002/jps.2600831020openalex-snapshot
Enhancement of Intestinal Insulin Absorption by Bile Salt–Fatty Acid Mixed Micelles in Dogs
inferredcites →https://doi.org/10.1007/978-1-4899-1236-7_11openalex-snapshot
Insulin Structure and Stability
inferredcites →https://doi.org/10.1007/s10439-016-1558-xopenalex-snapshot
Delivery of Exenatide and Insulin Using Mucoadhesive Intestinal Devices
inferredcites →https://doi.org/10.1007/s12010-014-0813-6openalex-snapshot
Recent Advances in the Applications of Ionic Liquids in Protein Stability and Activity: A Review
inferredcites →https://doi.org/10.1007/s41061-017-0110-2openalex-snapshot
Proteins in Ionic Liquids: Current Status of Experiments and Simulations
inferredcites →https://doi.org/10.1016/0024-3205(78)90568-4openalex-snapshot
Choline chloride in methylphenidate- and apomorphine-induced stereotypy
inferredcites →https://doi.org/10.1016/j.addr.2016.02.004openalex-snapshot
Current status of selected oral peptide technologies in advanced preclinical development and in clinical trials
inferredcites →https://doi.org/10.1016/j.bbrc.2005.07.142openalex-snapshot
Insulin-cell penetrating peptide hybrids with improved intestinal absorption efficiency
inferredcites →https://doi.org/10.1016/j.biomaterials.2009.06.055openalex-snapshot
Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery
inferredcites →https://doi.org/10.1016/j.biomaterials.2012.09.051openalex-snapshot
Sodium caprate as an enhancer of macromolecule permeation across tricellular tight junctions of intestinal cells
inferredcites →https://doi.org/10.1016/j.biotechadv.2015.02.010openalex-snapshot
Polymer-based nanoparticles for oral insulin delivery: Revisited approaches
inferredcites →https://doi.org/10.1016/j.ijpharm.2005.04.016openalex-snapshot
A lecithin-based microemulsion of rh-insulin with aprotinin for oral administration: Investigation of hypoglycemic effects in non-diabetic and STZ-induced diabetic rats
inferredcites →https://doi.org/10.1016/j.ijpharm.2006.07.026openalex-snapshot
Lectin-modified solid lipid nanoparticles as carriers for oral administration of insulin
inferredcites →https://doi.org/10.1016/j.jconrel.2007.05.019openalex-snapshot
Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles
inferredcites →https://doi.org/10.1016/j.jmb.2004.05.023openalex-snapshot
How Insulin Binds: the B-Chain α-Helix Contacts the L1 β-Helix of the Insulin Receptor
inferredcites →https://doi.org/10.1016/j.nano.2015.02.016openalex-snapshot
Intestinal absorption of fluorescently labeled nanoparticles
inferredcites →https://doi.org/10.1016/j.tiv.2005.03.006openalex-snapshot
Correlation of in vitro cytotoxicity with paracellular permeability in Caco-2 cells
inferredcites →https://doi.org/10.1016/s0015-6264(79)80035-8openalex-snapshot
Geranic acid
inferredcites →https://doi.org/10.1016/s0378-5173(02)00486-6openalex-snapshot
Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo
inferredcites →https://doi.org/10.1021/acs.chemrev.7b00246openalex-snapshot
Introduction: Ionic Liquids
inferredcites →https://doi.org/10.1021/bm0703923openalex-snapshot
Oral Bioavailability of Insulin Contained in Polysaccharide Nanoparticles
inferredcites →https://doi.org/10.1021/jp0766050openalex-snapshot
Protein Structure and Dynamics in Ionic Liquids. Insights from Molecular Dynamics Simulation Studies
inferredcites →https://doi.org/10.1021/js9601400openalex-snapshot
Transcellular Delivery of an Insulin-Transferrin Conjugate in Enterocyte-like Caco-2 Cells
inferredcites →https://doi.org/10.1021/mp500790topenalex-snapshot
Transformation of Poorly Water-Soluble Drugs into Lipophilic Ionic Liquids Enhances Oral Drug Exposure from Lipid Based Formulations
inferredcites →https://doi.org/10.1039/c2ra22277aopenalex-snapshot
Prevention of insulin self-aggregation by a protic ionic liquid
inferredcites →https://doi.org/10.1039/c3cc48650hopenalex-snapshot
Ionic liquids provide unique opportunities for oral drug delivery: structure optimization and in vivo evidence of utility
inferredcites →https://doi.org/10.1039/c6md00358copenalex-snapshot
Ionic liquids as a potential tool for drug delivery systems
inferredcites →https://doi.org/10.1073/pnas.1403995111openalex-snapshot
Ionic liquids as a class of materials for transdermal delivery and pathogen neutralization
inferredcites →https://doi.org/10.1080/10611860290022688openalex-snapshot
Absorption Enhancing Effect of Labrasol on the Intestinal Absorption of Insulin in Rats
inferredcites →https://doi.org/10.1111/j.1753-4887.2009.00246.xopenalex-snapshot
Choline: an essential nutrient for public health
inferredcites →https://doi.org/10.1111/jphp.12607openalex-snapshot
Oral delivery of insulin for treatment of diabetes: status quo, challenges and opportunities
inferredcites →https://doi.org/10.1126/science.1090313openalex-snapshot
Ionic Liquids--Solvents of the Future?
inferredcites →https://doi.org/10.1177/193229681300700228openalex-snapshot
Oral Insulin Delivery: How Far are We?
inferredcites →https://doi.org/10.1177/1932296814529988openalex-snapshot
Oral Insulin Reloaded
inferredcites →https://doi.org/10.1177/1932296817691303openalex-snapshot
Oral Insulin Delivery in a Physiologic Context: Review
inferredcites →https://doi.org/10.1185/03007990902905724openalex-snapshot
Impact of fear of insulin or fear of injection on treatment outcomes of patients with diabetes
inferredcites →https://doi.org/10.1186/preaccept-2071959743130788openalex-snapshot
Using ionic liquids in whole-cell biocatalysis for the nucleoside acylation
inferredcites →https://doi.org/10.1201/9781315117584openalex-snapshot
Drug Delivery
inferredcites →https://doi.org/10.1517/17425247.2013.736962openalex-snapshot
Eudragit®: a technology evaluation
inferredcites →https://doi.org/10.1517/17425247.2013.808185openalex-snapshot
Ionic liquids in drug delivery
inferredcites →https://doi.org/10.2147/dddt.s79322openalex-snapshot
Insulin administration: present strategies and future directions for a noninvasive (possibly more physiological) delivery
inferredcites →https://doi.org/10.2337/dc09-1348openalex-snapshot
Correlates of Insulin Injection Omission
inferredcites →https://doi.org/10.4103/0250-474x.42967openalex-snapshot
Protein and peptide drug delivery: Oral approaches
inferredcites →https://doi.org/10.4239/wjd.v6.i6.850openalex-snapshot
Diabetes mellitus: The epidemic of the century

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3967508openalex-extracted
inferred← citeshttps://doi.org/10.2139/ssrn.4096144openalex-extracted
Rheology of the Electric Double Layer In Ionic Liquid Solutions: Effects of Ion Concentration and Anion Structures
inferred← citeshttps://doi.org/10.1002/9781119660699.ch31openalex-snapshot
Oral Delivery of Therapeutic Peptides: Strategies for Product Development
inferred← citeshttps://doi.org/10.1002/adfm.201910168openalex-snapshot
Liver‐Target and Glucose‐Responsive Polymersomes toward Mimicking Endogenous Insulin Secretion with Improved Hepatic Glucose Utilization
inferred← citeshttps://doi.org/10.1002/adfm.202004257openalex-snapshot
Comparison of Ionic Liquids and Chemical Permeation Enhancers for Transdermal Drug Delivery
inferred← citeshttps://doi.org/10.1002/adfm.202104148openalex-snapshot
Antimicrobial Ionic Liquid‐Based Materials for Biomedical Applications
inferred← citeshttps://doi.org/10.1002/adfm.202306644openalex-snapshot
Interactions of Choline and Geranate (CAGE) and Choline Octanoate (CAOT) Deep Eutectic Solvents with Lipid Bilayers
inferred← citeshttps://doi.org/10.1002/adhm.201801123openalex-snapshot
Protein Corona Liposomes Achieve Efficient Oral Insulin Delivery by Overcoming Mucus and Epithelial Barriers
inferred← citeshttps://doi.org/10.1002/adhm.202001455openalex-snapshot
Enhancement of Anticancer Efficacy and Tumor Penetration of Sorafenib by Ionic Liquids
inferred← citeshttps://doi.org/10.1002/adhm.202002192openalex-snapshot
Modulation of Gastrointestinal Mucus Properties with Ionic Liquids for Drug Delivery
inferred← citeshttps://doi.org/10.1002/adhm.202100585openalex-snapshot
A Deep Eutectic Solvent‐Based Approach to Intravenous Formulation
inferred← citeshttps://doi.org/10.1002/adhm.202102685openalex-snapshot
Ionic Liquid‐Mediated Transdermal Delivery of Thrombosis‐Detecting Nanosensors
inferred← citeshttps://doi.org/10.1002/adhm.202400327openalex-snapshot
Localization of Intramuscular mRNA Delivery Using Deep Eutectic‐Lipid Nanocomposites
inferred← citeshttps://doi.org/10.1002/adhm.202500946openalex-snapshot
Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery
inferred← citeshttps://doi.org/10.1002/adhm.71494openalex-snapshot
Selective Blood Cell Hitchhiking in Whole Blood With Ionic Liquid‐Coated PLGA Nanoparticles to Redirect Biodistribution After Intravenous Injection
inferred← citeshttps://doi.org/10.1002/adma.201901103openalex-snapshot
Design Principles of Ionic Liquids for Transdermal Drug Delivery
inferred← citeshttps://doi.org/10.1002/adma.201901935openalex-snapshot
Oral Delivery of Biologics for Precision Medicine
inferred← citeshttps://doi.org/10.1002/adma.201902004openalex-snapshot
Glucose‐Responsive Insulin and Delivery Systems: Innovation and Translation
inferred← citeshttps://doi.org/10.1002/adma.202102044openalex-snapshot
A pH‐Triggered Self‐Unpacking Capsule Containing Zwitterionic Hydrogel‐Coated MOF Nanoparticles for Efficient Oral Exendin‐4 Delivery
inferred← citeshttps://doi.org/10.1002/adma.202206821openalex-snapshot
Oral Delivery of siRNA Using Fluorinated, Small‐Sized Nanocapsules toward Anti‐Inflammation Treatment
inferred← citeshttps://doi.org/10.1002/admt.202501893openalex-snapshot
Unveiling Tunable “Ghost” to “Non‐Ghost” Matrix Transition Facilitated Through Green Bio‐Ionic Liquid (BIL) Resins Using CPIP‐3D Printing
inferred← citeshttps://doi.org/10.1002/adtp.201900125openalex-snapshot
Robotics in the Gut
inferred← citeshttps://doi.org/10.1002/adtp.202000041openalex-snapshot
Stabilization and Topical Skin Delivery of Framework Nucleic Acids using Ionic Liquids
inferred← citeshttps://doi.org/10.1002/adtp.202000180openalex-snapshot
Choline‐Geranate Deep Eutectic Solvent Improves Stability and Half‐Life of Glucagon‐Like Peptide‐1
inferred← citeshttps://doi.org/10.1002/adtp.202200096openalex-snapshot
The Impact of Water on Choline‐2‐Octenoic Ionic Liquid‐Facilitated Transdermal Transport
inferred← citeshttps://doi.org/10.1002/adtp.202200332openalex-snapshot
Ionic Liquids: Momentous Tools in Transdermal Delivery of Biomacromolecules
inferred← citeshttps://doi.org/10.1002/adtp.202300127openalex-snapshot
Managing Diabetes with Hydrogel Drug Delivery
inferred← citeshttps://doi.org/10.1002/adtp.202400090openalex-snapshot
Designer Solvents for Pharmaceutics: Role of Ionic Liquids/ Deep Eutectic Solvents in Pharmaceutical Formulations
inferred← citeshttps://doi.org/10.1002/adts.202400943openalex-snapshot
Hydration Pattern of Ionic Liquids in the Stabilization of Insulin Dimer: A Computational Perspective
inferred← citeshttps://doi.org/10.1002/advs.202004819openalex-snapshot
Recent Advances in Ionic Liquids in Biomedicine
inferred← citeshttps://doi.org/10.1002/advs.202206756openalex-snapshot
An Ionic Liquid Ablation Agent for Local Ablation and Immune Activation in Pancreatic Cancer
inferred← citeshttps://doi.org/10.1002/advs.202207381openalex-snapshot
Regulating Type H Vessel Formation and Bone Metabolism via Bone‐Targeting Oral Micro/Nano‐Hydrogel Microspheres to Prevent Bone Loss
inferred← citeshttps://doi.org/10.1002/advs.202400843openalex-snapshot
Gastrointestinal Permeation Enhancers Beyond Sodium Caprate and SNAC ‐ What is Coming Next?
inferred← citeshttps://doi.org/10.1002/ange.202205609openalex-snapshot
Enabling Sustainable Chemistry with Ionic Liquids and Deep Eutectic Solvents: A Fad or the Future?
inferred← citeshttps://doi.org/10.1002/ange.202214795openalex-snapshot
Recent Advances in Oral and Transdermal Protein Delivery Systems
inferred← citeshttps://doi.org/10.1002/anie.202205609openalex-snapshot
Enabling Sustainable Chemistry with Ionic Liquids and Deep Eutectic Solvents: A Fad or the Future?
inferred← citeshttps://doi.org/10.1002/anie.202214795openalex-snapshot
Recent Advances in Oral and Transdermal Protein Delivery Systems
inferred← citeshttps://doi.org/10.1002/btm2.10191openalex-snapshot
Clinical translation of choline and geranic acid deep eutectic solvent
inferred← citeshttps://doi.org/10.1002/btm2.10405openalex-snapshot
Translation of ionic liquids to be enteric nanoparticles for facilitating oral absorption of cyclosporine A
inferred← citeshttps://doi.org/10.1002/cben.202300051openalex-snapshot
Unlocking the Anticancer Potential of Ionic Liquids
inferred← citeshttps://doi.org/10.1002/cbic.202300540openalex-snapshot
Ligand‐Independent Activation of Aryl Hydrocarbon Receptor and Attenuation of Glutamine Levels by Natural Deep Eutectic Solvent
inferred← citeshttps://doi.org/10.1002/gch2.202200064openalex-snapshot
A Long‐Lasting Skin Protectant Based on CG‐101, a Deep Eutectic Solvent Comprising Choline and Geranic Acid
inferred← citeshttps://doi.org/10.1002/jbm.a.37485openalex-snapshot
Choline and geranic acid (CAGE) ionic liquids inhibit both elastase activity and growth of oral bacteria
inferred← citeshttps://doi.org/10.1002/jpen.2577openalex-snapshot
Association between dietary total choline and abdominal aorta calcification among older US adults: A cross‐sectional study of the National Health and Nutrition Examination Survey
inferred← citeshttps://doi.org/10.1002/slct.202002026openalex-snapshot
Ultrasound‐Assisted Natural Deep Eutectic Solvents as Separation‐Free Extraction Media for Hydroxytyrosol from Olives
inferred← citeshttps://doi.org/10.1002/smll.202409936openalex-snapshot
Regulating Mitochondrial Aging via Targeting the Gut‐Bone Axis in BMSCs With Oral Hydrogel Microspheres to Inhibit Bone Loss
inferred← citeshttps://doi.org/10.1002/smll.202500403openalex-snapshot
Microrheology of Ionic Liquid Doped Mucus for an Efficient Delivery of Protein‐Based Oral Drugs
inferred← citeshttps://doi.org/10.1002/smtd.202401355openalex-snapshot
Oral Delivery Strategies for Biological Drugs
inferred← citeshttps://doi.org/10.1002/tcr.202300026openalex-snapshot
Pharmaceutical Applications of Ionic Liquids: A Personal Account
inferred← citeshttps://doi.org/10.1007/978-3-030-53069-3_2openalex-snapshot
Deep Eutectic Solvents for Innovative Pharmaceutical Formulations
inferred← citeshttps://doi.org/10.1007/978-3-030-55359-3_6openalex-snapshot
Stem Cell Applications in Metabolic Disorders: Diabetes Mellitus
inferred← citeshttps://doi.org/10.1007/978-3-030-96534-1_7openalex-snapshot
Ionic Liquids as Greener Solvents for Sample Pretreatment of Environmental, Pharmaceutical, and Biological Samples
inferred← citeshttps://doi.org/10.1007/978-981-16-4365-1_1openalex-snapshot
Design Principles for Ionic Liquids in Drug Delivery Systems
inferred← citeshttps://doi.org/10.1007/978-981-16-4365-1_10openalex-snapshot
Ionic Liquids for Transdermal Vaccination
inferred← citeshttps://doi.org/10.1007/978-981-16-4365-1_3openalex-snapshot
Ionic Liquids for Transdermal Drug Delivery: Choline Geranate System as a Case Study
inferred← citeshttps://doi.org/10.1007/978-981-16-4365-1_6openalex-snapshot
Ionic Liquid-Based Oral Drug Delivery Systems
inferred← citeshttps://doi.org/10.1007/978-981-16-7483-9_18openalex-snapshot
Ionogels for Biomedical Applications
inferred← citeshttps://doi.org/10.1007/978-981-19-2572-6_8openalex-snapshot
Exploring the Scope of Developing Ionic Liquid-Based Drugs
inferred← citeshttps://doi.org/10.1007/978-981-97-9230-6_15openalex-snapshot
Herbal Formulations: Development, Challenges, Testing, Stability, and Regulatory Guidelines
inferred← citeshttps://doi.org/10.1007/s00216-018-1559-8openalex-snapshot
Cost-effective imprinting to minimize consumption of template in room-temperature ionic liquid for fast purification of chlorogenic acid from the extract of E. ulmoides leaves
inferred← citeshttps://doi.org/10.1007/s11095-022-03260-8openalex-snapshot
Ionic Liquids: Promising Approach for Oral Drug Delivery
inferred← citeshttps://doi.org/10.1007/s11095-022-03322-xopenalex-snapshot
Recent Developments in Ionic Liquid-Assisted Topical and Transdermal Drug Delivery
inferred← citeshttps://doi.org/10.1007/s11095-023-03641-7openalex-snapshot
Exploiting Apical Sodium-Dependent Bile Acid Transporter (ASBT)-Mediated Endocytosis with Multi-Functional Deoxycholic Acid Grafted Alginate Amide Nanoparticles as an Oral Insulin Delivery System
inferred← citeshttps://doi.org/10.1007/s11581-021-04201-yopenalex-snapshot
Ionic liquids: a state of the art for biomedical applications
inferred← citeshttps://doi.org/10.1007/s11581-026-07526-8openalex-snapshot
Ionic liquids for metal nanoparticle synthesis and bio-functionalization: trends and future perspectives
inferred← citeshttps://doi.org/10.1007/s12039-020-01866-2openalex-snapshot
Rational design, preparation and characterization of a ternary non-ionic room-temperature deep eutectic solvent derived from urea, acetamide, and sorbitol
inferred← citeshttps://doi.org/10.1007/s12551-020-00754-wopenalex-snapshot
Mechanisms of action of ionic liquids on living cells: the state of the art
inferred← citeshttps://doi.org/10.1007/s12551-023-01173-3openalex-snapshot
Ionic liquids meet lipid bilayers: a state-of-the-art review
inferred← citeshttps://doi.org/10.1007/s12551-024-01261-yopenalex-snapshot
Ionic liquids as stabilisers of therapeutic protein formulations: a review of insulin and monoclonal antibodies
inferred← citeshttps://doi.org/10.1007/s13346-021-00905-wopenalex-snapshot
Nanocomposite systems for precise oral delivery of drugs and biologics
inferred← citeshttps://doi.org/10.1007/s13346-026-02179-6openalex-snapshot
A self-unfolding polymer foil loaded with a permeation enhancer Ionogel for superior oral peptide delivery
inferred← citeshttps://doi.org/10.1016/b978-0-12-817386-2.00008-1openalex-snapshot
Recent insights on solubility and stability of biomolecules in ionic liquid
inferred← citeshttps://doi.org/10.1016/b978-0-12-821061-1.00001-0openalex-snapshot
Landscape for oral delivery of peptides
inferred← citeshttps://doi.org/10.1016/b978-0-12-821352-0.00015-0openalex-snapshot
Ionic solvents for transdermal drug delivery
inferred← citeshttps://doi.org/10.1016/b978-0-12-821885-3.00010-4openalex-snapshot
Emerging trends in ionic liquid-based drugs: An update
inferred← citeshttps://doi.org/10.1016/b978-0-443-15960-2.00002-7openalex-snapshot
Emerging need of delivery systems for plant metabolites
inferred← citeshttps://doi.org/10.1016/b978-0-443-30272-5.00012-3openalex-snapshot
Oral insulin delivery—Challenges and strategies
inferred← citeshttps://doi.org/10.1016/j.ab.2024.115616openalex-snapshot
Molecularly imprinted polymers in the analysis of chlorogenic acid: A review
inferred← citeshttps://doi.org/10.1016/j.actbio.2019.05.051openalex-snapshot
Engineering the vasculature for islet transplantation
inferred← citeshttps://doi.org/10.1016/j.addr.2020.05.007openalex-snapshot
Systemic delivery of peptides by the oral route: Formulation and medicinal chemistry approaches
inferred← citeshttps://doi.org/10.1016/j.addr.2021.02.001openalex-snapshot
Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
inferred← citeshttps://doi.org/10.1016/j.addr.2021.113899openalex-snapshot
Nanotechnologies for the delivery of biologicals: Historical perspective and current landscape
inferred← citeshttps://doi.org/10.1016/j.addr.2021.113925openalex-snapshot
Formulation strategies to improve the efficacy of intestinal permeation enhancers,
inferred← citeshttps://doi.org/10.1016/j.addr.2021.114097openalex-snapshot
Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
inferred← citeshttps://doi.org/10.1016/j.addr.2023.114861openalex-snapshot
Lipid nanoparticle-mediated drug delivery to the brain
inferred← citeshttps://doi.org/10.1016/j.addr.2023.115157openalex-snapshot
Potentials of ionic liquids to overcome physical and biological barriers
inferred← citeshttps://doi.org/10.1016/j.ajps.2024.100900openalex-snapshot
Ionic liquids as the effective technology for enhancing transdermal drug delivery: Design principles, roles, mechanisms, and future challenges
inferred← citeshttps://doi.org/10.1016/j.apsb.2021.04.001openalex-snapshot
Oral delivery of proteins and peptides: Challenges, status quo and future perspectives
inferred← citeshttps://doi.org/10.1016/j.apsb.2024.02.019openalex-snapshot
Oral peptide therapeutics for diabetes treatment: State-of-the-art and future perspectives
inferred← citeshttps://doi.org/10.1016/j.apsb.2025.10.037openalex-snapshot
Deep eutectic solvents@enteric technology for orally delivering anticoagulant macromolecule drug
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2020.120323openalex-snapshot
Tailored elasticity combined with biomimetic surface promotes nanoparticle transcytosis to overcome mucosal epithelial barrier
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2021.121069openalex-snapshot
Topical treatment of periodontitis using an iongel
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2024.108316openalex-snapshot
Ionic liquids and deep eutectic solvents for the stabilization of biopharmaceuticals: A review
inferred← citeshttps://doi.org/10.1016/j.cclet.2020.02.035openalex-snapshot
The application of biomacromolecules to improve oral absorption by enhanced intestinal permeability: A mini-review
inferred← citeshttps://doi.org/10.1016/j.cclet.2025.111170openalex-snapshot
Emerging trends in permeation-enhancing technologies for oral peptide delivery
inferred← citeshttps://doi.org/10.1016/j.cclet.2025.111818openalex-snapshot
Natural products self-assembling permeation enhancer for intestinal delivery of calcitonin
inferred← citeshttps://doi.org/10.1016/j.cej.2022.134928openalex-snapshot
Impact of bile salt on solution-mediated phase transformation of pharmaceutical cocrystals: The importance of coformer release kinetics
inferred← citeshttps://doi.org/10.1016/j.cis.2024.103244openalex-snapshot
Review of ionic liquid and ionogel-based biomaterials for advanced drug delivery
inferred← citeshttps://doi.org/10.1016/j.cjche.2020.11.015openalex-snapshot
The potential of ionic liquids in biopharmaceutical engineering
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2019.110443openalex-snapshot
Smart pH-responsive polymeric micelles for programmed oral delivery of insulin
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2026.116082openalex-snapshot
Functional ionic liquids for enhanced transdermal drug delivery: Recent advances and future perspectives
inferred← citeshttps://doi.org/10.1016/j.crbiot.2022.10.005openalex-snapshot
Ionic liquid-mediated skin technologies: Recent advances and prospects
inferred← citeshttps://doi.org/10.1016/j.drudis.2019.09.018openalex-snapshot
Ionic liquids: green and tailor-made solvents in drug delivery
inferred← citeshttps://doi.org/10.1016/j.drudis.2021.03.003openalex-snapshot
Computational avenues in oral protein and peptide therapeutics
inferred← citeshttps://doi.org/10.1016/j.drudis.2024.104109openalex-snapshot
Ionic liquid-based formulation approaches for enhanced transmucosal drug delivery
inferred← citeshttps://doi.org/10.1016/j.ejmech.2025.117273openalex-snapshot
Sequential pH/GSH-responsive stealth nanoparticles for co-delivery of anti-PD-1 antibody and paclitaxel to enhance chemoimmunotherapy of lung cancer
inferred← citeshttps://doi.org/10.1016/j.ejphar.2019.172625openalex-snapshot
Treatment strategies against diabetes: Success so far and challenges ahead
inferred← citeshttps://doi.org/10.1016/j.ejps.2020.105685openalex-snapshot
Comparison of the effects of the intestinal permeation enhancers, SNAC and sodium caprate (C10): Isolated rat intestinal mucosae and sacs
inferred← citeshttps://doi.org/10.1016/j.ejps.2021.105931openalex-snapshot
Novel amorphous solid dispersion based on natural deep eutectic solvent for enhancing delivery of anti-tumor RA-XII by oral administration in rats
inferred← citeshttps://doi.org/10.1016/j.ejps.2026.107484openalex-snapshot
Deep eutectic systems as enabling pharmaceutical formulations: mechanisms and applications
inferred← citeshttps://doi.org/10.1016/j.fluid.2020.112919openalex-snapshot
The impact of oligomeric anions on the speciation of protic ionic liquids
inferred← citeshttps://doi.org/10.1016/j.fmre.2023.12.013openalex-snapshot
Ionic liquids inhibit the dynamic transition from α-helices to β-sheets in peptides
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2022.01.048openalex-snapshot
Glucose sensitive konjac glucomannan/concanavalin A nanoparticles as oral insulin delivery system
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2022.01.134openalex-snapshot
Recent progress in polymeric non-invasive insulin delivery
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2022.03.144openalex-snapshot
An overview of oral insulin delivery strategies (OIDS)
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2022.09.165openalex-snapshot
Ionically cross-linked alginate-chitosan core-shell hydrogel beads for oral delivery of insulin
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2023.125114openalex-snapshot
Oral insulin delivery: Barriers, strategies, and formulation approaches: A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.132208openalex-snapshot
Dissecting the stability of Atezolizumab with renewable amino acid-based ionic liquids: Colloidal stability and anticancer activity under thermal stress
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.135988openalex-snapshot
A review of biopolymer-based hydrogels and IoT integration for enhanced diabetes diagnosis, management, and treatment
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2020.119953openalex-snapshot
Development of piroxicam mini-tablets enabled by spherical cocrystallization
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.121129openalex-snapshot
Methotrexate-based ionic liquid as a potent anticancer drug for oral delivery: In vivo pharmacokinetics, biodistribution, and antitumor efficacy
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.121203openalex-snapshot
Deep eutectic systems: An overview of fundamental aspects, current understanding and drug delivery applications
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.121366openalex-snapshot
Applications of choline-based ionic liquids in drug delivery
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2022.121811openalex-snapshot
Deep eutectic solvents: Recent advances in fabrication approaches and pharmaceutical applications
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2022.122083openalex-snapshot
Oil-in-ionic liquid nanoemulsion-based adjuvant simultaneously enhances the stability and immune responses of inactivated foot-and-mouth disease virus
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2025.126369openalex-snapshot
Choline chloride–malic acid Natural Deep Eutectic Solvent containing hydrophobic drugs: Insights into solubility and permeability behavior in digestive tract models
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2026.127374openalex-snapshot
Antifungal drug-loaded ionic liquid-in-water emulsion for nail fungal infections
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2026.127486openalex-snapshot
Ionic liquid self-assembly enables high-loading inhalable delivery of remdesivir
inferred← citeshttps://doi.org/10.1016/j.ipha.2026.03.001openalex-snapshot
Advancements in transdermal drug delivery using ionic liquids: Design strategies, functional roles, mechanisms, and future challenges
inferred← citeshttps://doi.org/10.1016/j.jcis.2021.02.002openalex-snapshot
Effect of ionic liquids on the fluorescence properties and aggregation of superfolder green fluorescence protein
inferred← citeshttps://doi.org/10.1016/j.jcis.2024.12.187openalex-snapshot
Colloidal ionogels: Controlled assembly and self-propulsion upon tunable swelling
inferred← citeshttps://doi.org/10.1016/j.jcis.2025.139463openalex-snapshot
Engineered choline–Salcaprozate ionic liquids for enhanced non-invasive delivery of macromolecular antidiabetics
inferred← citeshttps://doi.org/10.1016/j.jconrel.2019.01.037openalex-snapshot
Intestinal iontophoresis from mucoadhesive patches: a strategy for oral delivery
inferred← citeshttps://doi.org/10.1016/j.jconrel.2019.08.008openalex-snapshot
Labrasol® is an efficacious intestinal permeation enhancer across rat intestine: Ex vivo and in vivo rat studies
inferred← citeshttps://doi.org/10.1016/j.jconrel.2019.09.019openalex-snapshot
Emerging frontiers of deep eutectic solvents in drug discovery and drug delivery systems
inferred← citeshttps://doi.org/10.1016/j.jconrel.2020.03.018openalex-snapshot
Oral delivery of sorafenib through spontaneous formation of ionic liquid nanocomplexes
inferred← citeshttps://doi.org/10.1016/j.jconrel.2020.07.021openalex-snapshot
Silica nanoparticles: A promising platform for enhanced oral delivery of macromolecules
inferred← citeshttps://doi.org/10.1016/j.jconrel.2020.07.037openalex-snapshot
Ionic liquid-mediated delivery of insulin to buccal mucosa
inferred← citeshttps://doi.org/10.1016/j.jconrel.2020.10.024openalex-snapshot
Design of a self-unfolding delivery concept for oral administration of macromolecules
inferred← citeshttps://doi.org/10.1016/j.jconrel.2021.08.032openalex-snapshot
Ionic liquids as a useful tool for tailoring active pharmaceutical ingredients
inferred← citeshttps://doi.org/10.1016/j.jconrel.2021.11.020openalex-snapshot
Oral insulin delivery by epithelium microenvironment-adaptive nanoparticles
inferred← citeshttps://doi.org/10.1016/j.jconrel.2022.04.036openalex-snapshot
Oil-in-ionic liquid nanoemulsion-based intranasal delivery system for influenza split-virus vaccine
inferred← citeshttps://doi.org/10.1016/j.jconrel.2022.10.031openalex-snapshot
Core-shell nanosystems designed for effective oral delivery of polypeptide drugs
inferred← citeshttps://doi.org/10.1016/j.jconrel.2022.11.032openalex-snapshot
Insulin-loaded liposomes packaged in alginate hydrogels promote the oral bioavailability of insulin
inferred← citeshttps://doi.org/10.1016/j.jconrel.2023.12.045openalex-snapshot
Recent advances in oral insulin delivery technologies
inferred← citeshttps://doi.org/10.1016/j.jconrel.2024.01.008openalex-snapshot
Electromechanical convective drug delivery devices for overcoming diffusion barriers
inferred← citeshttps://doi.org/10.1016/j.jconrel.2024.09.035openalex-snapshot
Mechanism and performance of choline-based ionic liquids in enhancing nasal delivery of glucagon
inferred← citeshttps://doi.org/10.1016/j.jconrel.2024.10.034openalex-snapshot
Choline geranate (CAGE): A multifaceted ionic liquid for drug delivery
inferred← citeshttps://doi.org/10.1016/j.jconrel.2024.10.038openalex-snapshot
An ionic liquid-based adjuvant for modulating cellular and humoral immune responses
inferred← citeshttps://doi.org/10.1016/j.jconrel.2024.11.016openalex-snapshot
Bioinspired orthogonal-shaped protein–biometal nanocrystals enable oral protein absorption
inferred← citeshttps://doi.org/10.1016/j.jconrel.2024.11.036openalex-snapshot
Salcaprozate-based ionic liquids for GLP-1 gastric delivery: A mechanistic understanding of in vivo performance
inferred← citeshttps://doi.org/10.1016/j.jconrel.2026.115214openalex-snapshot
Transdermal delivery of biologics
inferred← citeshttps://doi.org/10.1016/j.jddst.2021.102694openalex-snapshot
Ionic liquids: Formulation avenues, drug delivery and therapeutic updates
inferred← citeshttps://doi.org/10.1016/j.jddst.2022.103912openalex-snapshot
Preparation and evaluation of ibrutinib lipid-based formulations
inferred← citeshttps://doi.org/10.1016/j.jddst.2023.104664openalex-snapshot
Ionic liquid combined with bile acid pathway for oral delivery of rhGH
inferred← citeshttps://doi.org/10.1016/j.jddst.2026.108624openalex-snapshot
Global research trends and conceptual evolution in nanoparticle-based insulin delivery: A scientometric analysis (2015–2024)
inferred← citeshttps://doi.org/10.1016/j.jddst.2026.108941openalex-snapshot
Molecular engineering of insulin analogues for oral bioavailability: A systematic review of structural modifications and formulation stability
inferred← citeshttps://doi.org/10.1016/j.jfo.2022.04.008openalex-snapshot
Physicochemical and microbiological stability of insulin eye drops in an artificial tear vehicle used in the treatment of refractory neurotrophic keratopathy
inferred← citeshttps://doi.org/10.1016/j.jgar.2020.03.022openalex-snapshot
Synergistic activity between colistin and the ionic liquids 1-methyl-3-dodecylimidazolium bromide, 1-dodecyl-1-methylpyrrolidinium bromide, or 1-dodecyl-1-methylpiperidinium bromide against Gram-negative bacteria
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2021.125215openalex-snapshot
Evaluating the hazardous impact of ionic liquids – Challenges and opportunities
inferred← citeshttps://doi.org/10.1016/j.jpha.2025.101359openalex-snapshot
Butyrate-based ionic liquid for improved oral bioavailability and synergistic anti-colorectal cancer activity of glycyrol
inferred← citeshttps://doi.org/10.1016/j.matdes.2026.115933openalex-snapshot
Designing biomaterial-based oral protein drug-delivery systems for therapeutics
inferred← citeshttps://doi.org/10.1016/j.matt.2021.08.011openalex-snapshot
Glucose-responsive oral insulin delivery platform for one treatment a day in diabetes
inferred← citeshttps://doi.org/10.1016/j.matt.2024.05.012openalex-snapshot
Ionic liquids: An innovative approach in drug delivery
inferred← citeshttps://doi.org/10.1016/j.matt.2024.101948openalex-snapshot
Efficient oral insulin delivery with sustained release by folate-conjugated metal-organic framework nanoparticles
inferred← citeshttps://doi.org/10.1016/j.medidd.2020.100079openalex-snapshot
Patient-centric design for peptide delivery: Trends in routes of administration and advancement in drug delivery technologies
inferred← citeshttps://doi.org/10.1016/j.molliq.2018.09.025openalex-snapshot
Fundamental importance of ionic interactions in the liquid phase: A review of recent studies of ionic liquids in biomedical and pharmaceutical applications
inferred← citeshttps://doi.org/10.1016/j.molliq.2020.114870openalex-snapshot
Synergistic/antagonistic cytotoxic effects in mixtures of ionic liquids with doxorubicin or mitoxantrone
inferred← citeshttps://doi.org/10.1016/j.molliq.2021.115283openalex-snapshot
Intermolecular interactions in natural deep eutectic solvents and their effects on the ultrasound-assisted extraction of artemisinin from Artemisia annua
inferred← citeshttps://doi.org/10.1016/j.molliq.2021.118145openalex-snapshot
Ionic liquids in pharmaceutical industry: A systematic review on applications and future perspectives
inferred← citeshttps://doi.org/10.1016/j.molliq.2022.118643openalex-snapshot
Ionic liquid transdermal delivery system: Progress, prospects, and challenges
inferred← citeshttps://doi.org/10.1016/j.molliq.2022.120529openalex-snapshot
Highly efficient conotoxin delivery enabled by a bio-derived ionic liquid
inferred← citeshttps://doi.org/10.1016/j.molliq.2022.120580openalex-snapshot
Insights into the applications and prospects of ionic liquids towards the chemistry of biomolecules
inferred← citeshttps://doi.org/10.1016/j.molliq.2022.121029openalex-snapshot
Bioderived deep eutectic solvent-based topical chemotherapy for squamous cell carcinoma of the skin
inferred← citeshttps://doi.org/10.1016/j.molliq.2023.122048openalex-snapshot
CO2 capture with green ionic liquid and deep eutectic solvent: A comparative study
inferred← citeshttps://doi.org/10.1016/j.molliq.2024.125841openalex-snapshot
Ionic liquid-based Ionogel: A novel strategy to improve dermal delivery and in vivo efficacy of etodolac in rheumatoid arthritis management
inferred← citeshttps://doi.org/10.1016/j.molliq.2024.126179openalex-snapshot
Low-melting mixture solvents as novel solubilizing agents: Improving tolvaptan formulation and therapeutic efficacy
inferred← citeshttps://doi.org/10.1016/j.molliq.2025.127454openalex-snapshot
Emerging applicative areas of ionic liquids in biomedical sciences: Unveiling new biological insights
inferred← citeshttps://doi.org/10.1016/j.molmed.2020.12.001openalex-snapshot
Avoiding a Sticky Situation: Bypassing the Mucus Barrier for Improved Local Drug Delivery
inferred← citeshttps://doi.org/10.1016/j.mtphys.2022.100925openalex-snapshot
Liquid formulations based on ionic liquids in biomedicine
inferred← citeshttps://doi.org/10.1016/j.mtsust.2025.101160openalex-snapshot
A review on the evolution of ionic liquids: Sustainable synthesis, applications, and future prospects
inferred← citeshttps://doi.org/10.1016/j.nantod.2023.101834openalex-snapshot
Oral delivery of anti-PD-L1 antibody for cancer immunotherapy against orthotopic colorectal tumors
inferred← citeshttps://doi.org/10.1016/j.phymed.2021.153890openalex-snapshot
Herbal nanomedicines: Recent advancements, challenges, opportunities and regulatory overview
inferred← citeshttps://doi.org/10.1016/j.procbio.2024.12.010openalex-snapshot
A comprehensive review on integration of cellular metabolic engineering and cell-free systems for microbial platforms
inferred← citeshttps://doi.org/10.1016/j.rineng.2023.101529openalex-snapshot
Malic acid-based deep eutectic solvent and its application in Insulin's structural stability
inferred← citeshttps://doi.org/10.1016/j.scp.2025.102046openalex-snapshot
Sustainable ionic liquid design for enhanced solubility and safety of Tamoxifen: A computational exploration
inferred← citeshttps://doi.org/10.1016/j.seppur.2025.135584openalex-snapshot
Preservation of biological systems and materials using deep eutectic solvents: Pinnacles and pitfalls
inferred← citeshttps://doi.org/10.1016/j.snb.2023.135227openalex-snapshot
Artificial muscle based on coiled CNT yarns and biofriendly ionogels
inferred← citeshttps://doi.org/10.1016/j.supflu.2019.02.026openalex-snapshot
3D aerogel of cellulose triacetate with supercritical antisolvent process for drug delivery
inferred← citeshttps://doi.org/10.1016/j.tips.2020.11.002openalex-snapshot
Developing Insulin Delivery Devices with Glucose Responsiveness
inferred← citeshttps://doi.org/10.1016/j.xphs.2026.104534openalex-snapshot
CAGE ionic liquid–mediated co-solubilization of lapatinib and resveratrol enhances cytotoxicity in lung cancer cells with uniform aerosolization for pulmonary delivery
inferred← citeshttps://doi.org/10.1016/s1875-5364(24)60742-9openalex-snapshot
Natural endogenous material-based vehicles for delivery of macromolecular drugs
inferred← citeshttps://doi.org/10.1021/acs.biomac.8b01530openalex-snapshot
Scalable Manufacturing of Enteric Encapsulation Systems for Site-Specific Oral Insulin Delivery
inferred← citeshttps://doi.org/10.1021/acs.chemrev.2c00344openalex-snapshot
Zwitterionic Biomaterials
inferred← citeshttps://doi.org/10.1021/acs.chemrev.3c00551openalex-snapshot
Do Ionic Liquids Exhibit the Required Characteristics to Dissolve, Extract, Stabilize, and Purify Proteins? Past-Present-Future Assessment
inferred← citeshttps://doi.org/10.1021/acs.jced.0c00746openalex-snapshot
Expanding the Applications of the SAFT-γ Mie Group-Contribution Equation of State: Prediction of Thermodynamic Properties and Phase Behavior of Mixtures
inferred← citeshttps://doi.org/10.1021/acs.jpcb.0c02328openalex-snapshot
MAS NMR Investigation of Molecular Order in an Ionic Liquid Crystal
inferred← citeshttps://doi.org/10.1021/acs.jpcb.1c00586openalex-snapshot
Effects of Ionic Liquids on Aqueous Urea Solutions: Insights into the Ionic Liquid-Assisted Protein Renaturation
inferred← citeshttps://doi.org/10.1021/acs.jpcb.3c02720openalex-snapshot
Transition Mechanism from the Metastable Two-Dimensional Gel to the Stable Three-Dimensional Crystal of Imidazolium-Based Ionic Liquids
inferred← citeshttps://doi.org/10.1021/acs.jpcb.5c01687openalex-snapshot
Hydrophobicity-Driven Enhancement of Hydrogen Bonding in Ionic Liquid Hybrid Solvents
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